Detailed information for compound 1075965

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 912.158 | Formula: C47H81N3O14
  • H donors: 5 H acceptors: 6 LogP: 4.12 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1)CNC(=O)O[C@H]1[C@H](C)O[C@H](C[C@@]1(C)OC)O[C@@H]1[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@H](N(C[C@@H](C[C@]([C@@H]([C@H]1C)O[C@@H]1O[C@H](C)C[C@@H]([C@H]1O)N(C)C)(C)O)C)C)C
  • InChi: 1S/C47H81N3O14/c1-16-35-47(10,56)39(52)30(6)50(13)25-26(2)22-45(8,55)40(63-43-37(51)34(49(11)12)21-27(3)59-43)28(4)38(29(5)42(53)61-35)62-36-23-46(9,58-15)41(31(7)60-36)64-44(54)48-24-32-17-19-33(57-14)20-18-32/h17-20,26-31,34-41,43,51-52,55-56H,16,21-25H2,1-15H3,(H,48,54)/t26-,27-,28+,29-,30-,31+,34+,35-,36+,37-,38+,39-,40-,41+,43+,45+,46-,47-/m1/s1
  • InChiKey: FANLFNHBBLXBGJ-JHTOMOPBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.2441 0.4936
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.1014 0.1014
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.4776 0.4776
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.193 0.193
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.4776 0.4776
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0779 1
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0545 0.1803
Plasmodium vivax protein kinase Crk2 0.0046 0.163 0.5388
Trichomonas vaginalis CMGC family protein kinase 0.005 0.193 0.4041
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.2531 0.2531
Entamoeba histolytica protein kinase, putative 0.0058 0.2441 0.4936
Schistosoma mansoni kinase 0.005 0.1936 0.1936
Leishmania major protein kinase, putative 0.0068 0.3025 0.6117
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0046 0.163 0.163
Giardia lamblia Kinase, CMGC CLK 0.0068 0.3025 0.6334
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.163 0.3413
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.186 0.3895
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0545 0.1803
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.4776 0.9657
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0098 0.4945 0.4945
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.2087 0.4369
Loa Loa (eye worm) hypothetical protein 0.0028 0.0545 0.0545
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0545 0.0545
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0058 0.2441 0.4936
Plasmodium vivax serine/threonine kinase-1, putative 0.0068 0.3025 1
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Echinococcus multilocularis 0.0064 0.2776 0.2776
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0545 0.0545
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0159 0.8735 1
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.124 0.124
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0058 0.2441 0.4936
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.1039 0.1039
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.005 0.193 0.3902
Loa Loa (eye worm) hypothetical protein 0.0064 0.2776 0.2776
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0779 0.5
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0046 0.163 0.163
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.6898 0.6898
Echinococcus multilocularis dual specificity protein kinase clk2 0.0068 0.3025 0.3025
Schistosoma mansoni jumonji domain containing protein 0.0074 0.3387 0.3387
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1549 0.1549
Echinococcus granulosus zinc finger protein 0.002 0.0004 0.0004
Entamoeba histolytica protein kinase, putative 0.0098 0.4945 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.1812 0.1812
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.4776 0.5166
Brugia malayi serine/threonine-protein kinase 6 0.0058 0.2441 0.2441
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0545 0.0545
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1549 0.1549
Brugia malayi Bromodomain containing protein 0.0038 0.1183 0.1183
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.4776 0.4776
Trypanosoma cruzi cdc2-related kinase 1 0.0046 0.163 0.3296
Trichomonas vaginalis AGC family protein kinase 0.0058 0.2441 0.5111
Schistosoma mansoni tar DNA-binding protein 0.013 0.6898 0.6898
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.2087 0.422
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.005 0.193 0.3902
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.1014 0.2124
Echinococcus multilocularis aurora kinase A 0.0058 0.2441 0.2441
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1549 0.1549
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.1798 0.1798
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0159 0.8735 0.8735
Schistosoma mansoni tar DNA-binding protein 0.013 0.6898 0.6898
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0094 0.4696 0.4696
Giardia lamblia Kinase, CMGC GSK 0.005 0.193 0.4041
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.4776 0.9657
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.186 0.3895
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1549 0.1549
Entamoeba histolytica protein kinase domain containing protein 0.005 0.193 0.3902
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0841 0.0841
Trypanosoma cruzi cdc2-related kinase 3 0.0046 0.163 0.3296
Trypanosoma brucei aurora B kinase 0.0058 0.2441 0.4936
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.2087 0.422
Echinococcus granulosus tar DNA binding protein 0.013 0.6898 0.6898
Loa Loa (eye worm) hypothetical protein 0.0033 0.0841 0.0841
Echinococcus granulosus peregrin 0.0031 0.0694 0.0694
Trichomonas vaginalis AGC family protein kinase 0.0058 0.2441 0.5111
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0046 0.163 0.163
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0159 0.8735 0.8735
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.1014 0.2051
Echinococcus granulosus cyclin dependent kinase 5 0.0046 0.163 0.163
Loa Loa (eye worm) TAR-binding protein 0.013 0.6898 0.6898
Brugia malayi serine/threonine protein kinase 6 0.0058 0.2441 0.2441
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.2087 0.2087
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.2087 0.422
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0098 0.4945 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.1337 0.1337
Brugia malayi jmjC domain containing protein 0.0036 0.1039 0.1039
Brugia malayi Protein kinase domain containing protein 0.0046 0.163 0.163
Trypanosoma cruzi aurora B kinase, putative 0.0058 0.2441 0.4936
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0545 0.1803
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.3025 0.3025
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0068 0.3025 0.3025
Trypanosoma brucei protein kinase, putative 0.0053 0.2087 0.422
Echinococcus multilocularis cyclin dependent kinase 5 0.0046 0.163 0.163
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0046 0.163 0.163
Schistosoma mansoni hypothetical protein 0.0028 0.0545 0.0545
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.4945 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0191 0.0191
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.1014 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0046 0.163 0.163
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.4945 1
Schistosoma mansoni protein kinase 0.0058 0.2441 0.2441
Trypanosoma cruzi cdc2-related kinase 3 0.0046 0.163 0.3296
Loa Loa (eye worm) hypothetical protein 0.0048 0.1798 0.1798
Echinococcus multilocularis cyclin dependent kinase 0.0046 0.163 0.163
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0046 0.163 0.3296
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0046 0.163 0.5388
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0068 0.3025 1
Brugia malayi cell division control protein 2 homolog 0.0046 0.163 0.163
Trypanosoma cruzi cdc2-related kinase 1 0.0046 0.163 0.3296
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.8735 0.8735
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.2087 0.2087
Brugia malayi serine/threonine kinase 12 0.0058 0.2441 0.2441
Brugia malayi Protein kinase domain containing protein 0.0068 0.3025 0.3025
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2087 0.4369
Echinococcus multilocularis dual specificity 0.0098 0.4945 0.4945
Giardia lamblia Kinase, PLK 0.0096 0.4776 1
Loa Loa (eye worm) inositol-1 0.0036 0.1014 0.1014
Schistosoma mansoni inositol monophosphatase 0.0036 0.1014 0.1014
Trichomonas vaginalis AGC family protein kinase 0.0058 0.2441 0.5111
Entamoeba histolytica protein kinase, putative 0.0098 0.4945 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.2087 0.422
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.2087 0.2087
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2087 0.4369
Echinococcus granulosus hypothetical protein 0.0064 0.2776 0.2776
Leishmania major protein kinase, putative 0.0068 0.3025 0.6117
Echinococcus multilocularis zinc finger protein 0.002 0.0004 0.0004
Schistosoma mansoni bromodomain containing protein 0.0064 0.2756 0.2756
Loa Loa (eye worm) AUR protein kinase 0.0058 0.2441 0.2441
Entamoeba histolytica protein kinase , putative 0.0058 0.2441 0.4936
Leishmania major protein kinase, putative 0.0058 0.2441 0.4936
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0545 0.0545
Trypanosoma brucei protein kinase, putative 0.005 0.193 0.3902
Brugia malayi intracellular kinase 0.005 0.193 0.193
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.3025 0.6334
Entamoeba histolytica cell division protein kinase 2, putative 0.0046 0.163 0.3296
Onchocerca volvulus 0.005 0.193 0.1691
Brugia malayi RNA recognition motif domain containing protein 0.013 0.6898 0.6898
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0098 0.4945 1
Entamoeba histolytica hypothetical protein 0.0098 0.4945 1
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.1014 0.1014
Entamoeba histolytica protein kinase, putative 0.005 0.193 0.3902
Trichomonas vaginalis CMGC family protein kinase 0.005 0.193 0.4041
Giardia lamblia Kinase, CMGC CDK 0.0046 0.163 0.3413
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0159 0.8735 0.8735
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.1014 0.2051
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0068 0.3025 0.6117
Entamoeba histolytica cell division protein kinase 2, putative 0.0046 0.163 0.3296
Trypanosoma brucei polo-like protein kinase 0.0096 0.4776 0.9657
Schistosoma mansoni tar DNA-binding protein 0.013 0.6898 0.6898
Giardia lamblia Kinase, CMGC CDK 0.0046 0.163 0.3413
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2087 0.4369
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0068 0.3025 0.6117
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.4776 0.9657
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0046 0.163 0.3296
Brugia malayi jmjC domain containing protein 0.0093 0.4581 0.4581
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.2087 0.422
Schistosoma mansoni inositol monophosphatase 0.0036 0.1014 0.1014
Loa Loa (eye worm) AUR protein kinase 0.0058 0.2441 0.2441
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.2087 0.422
Toxoplasma gondii aurora kinase 0.0058 0.2441 0.8069
Loa Loa (eye worm) hypothetical protein 0.0042 0.1381 0.1381
Entamoeba histolytica protein kinase, putative 0.0058 0.2441 0.4936
Giardia lamblia Aurora kinase 0.0058 0.2441 0.5111
Echinococcus multilocularis peregrin 0.0031 0.0694 0.0694
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1549 0.1549
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0159 0.8735 0.8735
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0058 0.2441 0.2441
Echinococcus multilocularis protein kinase shaggy 0.005 0.193 0.193
Giardia lamblia Kinase, CMGC GSK 0.005 0.193 0.4041
Trypanosoma brucei cdc2-related kinase 1 0.0046 0.163 0.3296
Plasmodium falciparum glycogen synthase kinase 3 0.005 0.193 0.638
Echinococcus multilocularis cyclin dependent kinase 1 0.0046 0.163 0.163
Schistosoma mansoni hypothetical protein 0.0033 0.0841 0.0841
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.1014 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0068 0.3025 0.6117
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0058 0.2441 0.2441
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0068 0.3025 0.6117
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.1039 0.1039
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Brugia malayi RNA binding protein 0.013 0.6898 0.6898
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0191 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.2087 0.2087
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.163 0.163
Brugia malayi TAR-binding protein 0.013 0.6898 0.6898
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.2087 0.2087
Brugia malayi Protein kinase domain containing protein 0.0098 0.4945 0.4945
Echinococcus granulosus aurora kinase A 0.0058 0.2441 0.2441
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0068 0.3025 0.6117
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.1014 0.3353
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.4945 0.4945
Loa Loa (eye worm) hypothetical protein 0.0043 0.1457 0.1457
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.1014 0.2051
Schistosoma mansoni zinc finger protein 0.002 0.0004 0.0004
Echinococcus granulosus protein kinase shaggy 0.005 0.193 0.193
Plasmodium falciparum phd finger protein, putative 0.0028 0.0545 0.1803
Echinococcus granulosus dual specificity protein kinase clk2 0.0068 0.3025 0.3025
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.4776 0.9657
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.193 0.193
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.1549 0.1549
Trypanosoma brucei cdc2-related kinase 3 0.0046 0.163 0.3296
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0068 0.3025 0.6117
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.1039 0.1039
Schistosoma mansoni tar DNA-binding protein 0.013 0.6898 0.6898
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1549 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.2441 0.2441
Brugia malayi Protein kinase domain containing protein 0.0159 0.8735 0.8735
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.4581 0.4581
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.1034 0.1034
Loa Loa (eye worm) AUR protein kinase 0.0058 0.2441 0.2441
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.1014 0.2051
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.4776 0.4776
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.2087 0.2087
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.1039 0.1039
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.4776 0.4776
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.2087 0.422
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.1034 0.1034
Plasmodium falciparum protein kinase 5 0.0046 0.163 0.5388
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Echinococcus granulosus glycogen synthase kinase 3 beta 0.005 0.193 0.193
Schistosoma mansoni hypothetical protein 0.0021 0.0071 0.0071
Echinococcus granulosus cyclin dependent kinase 1 0.0046 0.163 0.163
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.005 0.193 0.193
Plasmodium falciparum serine/threonine protein kinase, putative 0.0058 0.2441 0.8069
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.1014 0.2124
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0071 0.3225 0.3225
Brugia malayi Inositol-1 0.0036 0.1014 0.1014
Brugia malayi MAP kinase sur-1 0.0053 0.2087 0.2087
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.2087 0.6899
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.1014 0.2124
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.2434 0.2434
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0058 0.2441 0.4936
Plasmodium falciparum protein serine/threonine kinase-1 0.0068 0.3025 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.1798 0.1798
Schistosoma mansoni tar DNA-binding protein 0.013 0.6898 0.6898
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0918 0.0918
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.005 0.193 0.193
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.3025 0.3025
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.4581 0.4581
Trichomonas vaginalis AGC family protein kinase 0.0058 0.2441 0.5111
Echinococcus granulosus jumonji domain containing protein 0.0039 0.124 0.124
Entamoeba histolytica protein kinase domain containing protein 0.005 0.193 0.3902
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.163 0.163
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.4776 1
Echinococcus multilocularis tar DNA binding protein 0.013 0.6898 0.6898
Loa Loa (eye worm) RNA binding protein 0.013 0.6898 0.6898
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0159 0.8735 0.8735
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.1549 0.1549
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2087 0.4369
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.005 0.193 0.638
Brugia malayi PHD-finger family protein 0.0025 0.034 0.034
Brugia malayi Bromodomain containing protein 0.0075 0.3494 0.3494
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.1798 0.1798
Giardia lamblia PHD finger protein 15 0.0028 0.0545 0.1142
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0191 0.0191
Brugia malayi PHD-finger family protein 0.0028 0.0545 0.0545
Echinococcus granulosus dual specificity 0.0098 0.4945 0.4945
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.163 0.3413
Echinococcus granulosus cyclin dependent kinase 0.0046 0.163 0.163
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0058 0.2441 0.8069
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.1014 0.2051
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.4945 1
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.163 0.3413
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.2531 0.2531
Brugia malayi Bromodomain containing protein 0.0031 0.0694 0.0694
Loa Loa (eye worm) hypothetical protein 0.0094 0.4696 0.4696
Loa Loa (eye worm) hypothetical protein 0.0039 0.1188 0.1188
Plasmodium vivax glycogen synthase kinase 3, putative 0.005 0.193 0.638

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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