Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.7424 | 0.9414 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0068 | 0.708 | 0.9537 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.2951 | 0.3975 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.7424 | 0.9414 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.3391 | 0.3541 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.2951 | 0.3975 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0191 | 0.0242 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.7424 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.007 | 0.7424 | 0.715 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.3708 | 0.4995 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.7424 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0068 | 0.708 | 0.6769 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.7424 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.3708 | 0.4702 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.3378 | 0.2673 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.9228 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.7424 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.007 | 0.7424 | 0.9415 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0069 | 0.724 | 0.9751 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.007 | 0.7424 | 0.9999 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0068 | 0.708 | 0.9536 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.3708 | 0.4994 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.007 | 0.7424 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.3818 | 0.4014 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0068 | 0.708 | 0.9537 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.3708 | 0.3038 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.007 | 0.7424 | 0.9415 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0535 | 0.0679 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.7886 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.3708 | 0.4702 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.3708 | 0.4702 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.3708 | 0.4994 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.4163 | 0.4395 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.3708 | 0.4995 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.007 | 0.7424 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0535 | 0.0721 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.007 | 0.7424 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0068 | 0.708 | 0.8978 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.007 | 0.7424 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.3708 | 0.3892 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.7424 | 0.8004 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0069 | 0.724 | 0.9752 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0535 | 0.0721 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.