Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0056 | 0.0098 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0038 | 0.0045 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0038 | 0.0265 | 0.5772 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0017 | 0.001 | 0.0018 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0261 | 0.3088 | 0.3676 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0038 | 0.0045 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0169 | 0.1926 | 0.3368 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0459 | 0.7815 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0252 | 0.0441 |
Echinococcus multilocularis | smad | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0017 | 0.001 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0133 | 0.4453 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0252 | 0.0812 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0056 | 0.0056 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 0.0459 | 0.0459 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 0.0459 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0082 | 0.0823 | 0.0979 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0252 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1205 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0056 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0056 | 0.0066 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0252 | 0.5498 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0255 | 0.3008 | 0.5261 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0056 | 0.0544 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0038 | 0.8041 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0252 | 0.5498 |
Schistosoma mansoni | tar DNA-binding protein | 0.027 | 0.3201 | 0.3811 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0038 | 0.5 |
Onchocerca volvulus | 0.0096 | 0.1 | 0.975 | |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1205 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0056 | 0.0056 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0133 | 0.0233 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 0.0459 | 0.7665 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.027 | 0.3201 | 0.5598 |
Echinococcus granulosus | tar DNA binding protein | 0.027 | 0.3201 | 0.3811 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0133 | 0.2268 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0056 | 0.0098 |
Onchocerca volvulus | 0.0027 | 0.0133 | 0.1298 | |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0038 | 0.0265 | 0.0463 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0133 | 0.4453 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0265 | 0.2198 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0417 | 0.7098 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0096 | 0.1 | 0.1749 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0587 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0053 | 0.0459 | 0.0802 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0259 | 0.3051 | 0.5336 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0038 | 0.0639 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0017 | 0.001 | 0.0012 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0038 | 0.0818 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0056 | 0.0098 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0056 | 0.0066 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0133 | 0.0371 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 0.0459 | 0.7665 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0038 | 0.5 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0047 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0112 | 0.1205 | 0.1434 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.0047 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0133 | 0.0233 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0133 | 0.4453 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0252 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0252 | 0.0441 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0252 | 0.5498 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0439 | 0.0523 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0056 | 0.0544 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0252 | 0.0441 |
Onchocerca volvulus | 0.0021 | 0.0056 | 0.0544 | |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 0.0459 | 0.0546 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0252 | 0.0812 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0459 | 0.7815 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0056 | 0.0098 |
Brugia malayi | Smad1 | 0.0017 | 0.001 | 0.0018 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0056 | 0.0056 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 0.0459 | 0.0546 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0082 | 0.0823 | 0.1439 |
Echinococcus multilocularis | GPCR, family 2 | 0.0082 | 0.0823 | 0.0823 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0252 | 0.0441 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0823 | 0.1439 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0265 | 0.5772 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0133 | 0.0233 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0683 | 0.8401 | 0.8401 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0056 | 0.0066 |
Schistosoma mansoni | alpha-glucosidase | 0.0146 | 0.1629 | 0.1939 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0265 | 0.5772 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0252 | 0.4296 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.2737 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0056 | 0.0056 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0056 | 0.0098 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0252 | 0.5498 |
Onchocerca volvulus | 0.0051 | 0.0439 | 0.4281 | |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0038 | 0.0265 | 0.0315 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0252 | 0.4296 |
Schistosoma mansoni | survival motor neuron protein | 0.0096 | 0.1 | 0.119 |
Brugia malayi | MH2 domain containing protein | 0.0255 | 0.3008 | 0.5261 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0056 | 0.0066 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.202 | 0.2404 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0082 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0112 | 0.1205 | 0.1205 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0056 | 0.0098 |
Echinococcus multilocularis | Smad4 | 0.0017 | 0.001 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1205 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0252 | 0.0812 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0038 | 0.0265 | 0.0463 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0252 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0252 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0056 | 0.0056 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0056 | 0.0066 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0056 | 0.0056 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0252 | 0.03 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.0133 | 0.1105 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1205 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1 | 0.119 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.027 | 0.3201 | 0.5598 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0252 | 0.0812 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0082 | 0.0823 | 0.1439 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0252 | 0.5498 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0252 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0056 | 0.0098 |
Onchocerca volvulus | 0.0037 | 0.0252 | 0.2459 | |
Schistosoma mansoni | hypothetical protein | 0.0261 | 0.3088 | 0.3676 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0252 | 0.0812 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0252 | 0.0812 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0823 | 0.0979 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0056 | 0.0066 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0047 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0056 | 0.0066 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0056 | 0.0544 |
Echinococcus granulosus | Smad4 | 0.0017 | 0.001 | 0.0012 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0082 | 0.0823 | 0.0823 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0056 | 0.0098 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 0.0459 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0056 | 0.0098 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 0.0459 | 0.7815 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0265 | 0.4511 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0133 | 0.2268 |
Brugia malayi | hypothetical protein | 0.047 | 0.5718 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.047 | 0.5718 | 0.6807 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0056 | 0.0056 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.001 | 0.0018 |
Schistosoma mansoni | smad | 0.0017 | 0.001 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0252 | 0.0441 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0133 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0082 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0056 | 0.0098 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0133 | 0.4453 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0252 | 0.0812 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0133 | 0.4453 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Echinococcus multilocularis | tar DNA binding protein | 0.027 | 0.3201 | 0.3201 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0252 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0056 | 0.0098 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0252 | 0.03 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 0.0459 | 0.7815 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0082 | 0.0823 | 0.0979 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0056 | 0.0098 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0056 | 0.0098 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0265 | 0.4511 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0038 | 0.0265 | 0.5772 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0133 | 0.0371 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0252 | 0.0441 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.0012 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0082 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0459 | 0.0546 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0169 | 0.1926 | 0.2292 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0056 | 0.0098 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0082 | 0.0823 | 0.1439 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0038 | 0.0066 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0459 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.001 | 0.0018 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0252 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0252 | 0.0252 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0683 | 0.8401 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0252 | 0.0812 |
Trypanosoma brucei | glucosidase, putative | 0.0038 | 0.0265 | 0.4136 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | alpha-glucosidase | 0.0146 | 0.1629 | 0.1939 |
Schistosoma mansoni | Smad4 | 0.0017 | 0.001 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0082 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0259 | 0.3051 | 0.5336 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.001 | 0.0018 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0252 | 0.0441 |
Echinococcus granulosus | smad | 0.0017 | 0.001 | 0.0012 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0133 | 0.1105 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0265 | 0.5772 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0252 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0017 | 0.001 | 0.0012 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0255 | 0.3008 | 0.5261 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0265 | 0.5772 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0056 | 0.0066 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0252 | 0.5498 |
Schistosoma mansoni | alpha glucosidase | 0.0038 | 0.0265 | 0.0315 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0017 | 0.001 | 0.001 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0459 | 1 |
Onchocerca volvulus | 0.0037 | 0.0252 | 0.2459 | |
Leishmania major | alpha glucosidase II subunit, putative | 0.0038 | 0.0265 | 0.4511 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0082 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0265 | 0.2198 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0056 | 0.0098 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0587 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.0047 | 0.0426 |
Brugia malayi | hypothetical protein | 0.0112 | 0.1205 | 0.2107 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0252 | 0.0441 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0056 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0133 | 0.0233 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0038 | 0.1487 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0056 | 0.0066 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0177 | 0.202 | 0.3532 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0252 | 0.5498 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0133 | 0.4453 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0038 | 0.0311 |
Echinococcus multilocularis | tumor protein p63 | 0.0351 | 0.4218 | 0.4218 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0038 | 0.0265 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0252 | 0.0441 |
Onchocerca volvulus | 0.0098 | 0.1026 | 1 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0056 | 0.0066 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0252 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0038 | 0.0818 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 0.0459 | 0.0459 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 0.0459 | 0.7815 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0038 | 0.0066 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.0518 | 0.8824 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0587 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 0.0459 | 0.7815 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0056 | 0.0066 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0056 | 0.0098 |
Brugia malayi | TAR-binding protein | 0.027 | 0.3201 | 0.5598 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0056 | 0.0098 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0252 | 0.0441 |
Schistosoma mansoni | tar DNA-binding protein | 0.027 | 0.3201 | 0.3811 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0823 | 0.0979 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0265 | 0.5772 |
Loa Loa (eye worm) | TAR-binding protein | 0.027 | 0.3201 | 0.5598 |
Schistosoma mansoni | thyroid hormone receptor | 0.0282 | 0.3353 | 0.3991 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0038 | 0.0045 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0038 | 0.0018 |
Schistosoma mansoni | tar DNA-binding protein | 0.027 | 0.3201 | 0.3811 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0282 | 0.3353 | 0.3353 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.0587 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0261 | 0.3088 | 0.3088 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0683 | 0.8401 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0587 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0056 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.047 | 0.5718 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0112 | 0.1205 | 0.1434 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0265 | 0.5772 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.1926 | 0.1926 |
Loa Loa (eye worm) | Smad1 | 0.0017 | 0.001 | 0.0018 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0056 | 0.0056 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0252 | 0.0441 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0252 | 0.3907 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0169 | 0.1926 | 0.3368 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0056 | 0.0098 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0133 | 0.1105 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0056 | 0.0066 |
Brugia malayi | RNA binding protein | 0.027 | 0.3201 | 0.5598 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0017 | 0.001 | 0.0012 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0038 | 0.0818 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.3051 | 0.5336 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0439 | 0.0768 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.1205 | 0.1434 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0823 | 0.0979 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0587 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.0012 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.0047 | 0.185 |
Echinococcus granulosus | GPCR family 2 | 0.0082 | 0.0823 | 0.0979 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0133 | 0.4453 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0038 | 0.0639 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0056 | 0.0066 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.001 | 0.0018 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.1926 | 0.1926 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0056 | 0.0066 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0587 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0459 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0056 | 0.0066 |
Schistosoma mansoni | thyroid hormone receptor | 0.0282 | 0.3353 | 0.3991 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0056 | 0.0098 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0038 | 0.0639 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0252 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0252 | 0.0441 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0056 | 0.0066 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0082 | 0.0823 | 0.0823 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 0.0459 | 0.0802 |
Brugia malayi | RNA recognition motif domain containing protein | 0.027 | 0.3201 | 0.5598 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0252 | 0.0812 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0265 | 0.5772 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.047 | 0.5718 | 0.5718 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0056 | 0.0098 |
Echinococcus granulosus | tumor protein p63 | 0.0351 | 0.4218 | 0.5021 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0133 | 0.4453 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0133 | 0.2268 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0823 | 0.0979 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0259 | 0.3051 | 0.5336 |
Schistosoma mansoni | tar DNA-binding protein | 0.027 | 0.3201 | 0.3811 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0265 | 0.5772 |
Onchocerca volvulus | 0.0037 | 0.0252 | 0.2459 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0587 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0133 | 0.0233 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0056 | 0.0098 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0459 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0252 | 0.4296 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0056 | 0.0066 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0056 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.027 | 0.3201 | 0.3811 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.202 | 0.3532 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0056 | 0.0098 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0017 | 0.001 | 0.001 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.