Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0745 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0071 | 0.1137 | 0.1065 |
Echinococcus granulosus | pyruvate kinase | 0.0032 | 0.034 | 0.0327 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0399 | 0.0386 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0083 | 0.0069 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | TAR-binding protein | 0.0278 | 0.5441 | 0.6154 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Brugia malayi | isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0858 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0083 | 0.0069 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.6626 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0138 | 0.0062 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0083 | 0.0069 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0032 | 0.0329 | 0.1547 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | pyruvate kinase | 0.0032 | 0.034 | 0.0327 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0032 | 0.0329 | 0.2803 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0052 | 0.0758 | 0.0745 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0704 | 0.0691 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0083 | 0.0069 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0083 | 0.0069 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0886 | 0.0873 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0442 | 0.8841 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0442 | 0.8841 | 1 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0032 | 0.034 | 0.2611 |
Echinococcus multilocularis | heat shock protein 90 | 0.0032 | 0.0329 | 0.0315 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0071 | 0.1137 | 0.1065 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.0329 | 0.0315 |
Trichomonas vaginalis | heat shock protein, putative | 0.0025 | 0.0195 | 0.013 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0083 | 0.0069 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.1137 | 0.1065 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0181 | 0.1486 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0032 | 0.034 | 0.0385 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0071 | 0.1137 | 0.1065 |
Trichomonas vaginalis | esterase, putative | 0.0071 | 0.1137 | 0.115 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0032 | 0.0329 | 0.2504 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0278 | 0.5441 | 0.6118 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0071 | 0.1137 | 0.1286 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.2572 | 0.2842 |
Brugia malayi | heat shock protein 90 | 0.0032 | 0.0329 | 0.0372 |
Echinococcus granulosus | heat shock protein | 0.0032 | 0.0329 | 0.0315 |
Echinococcus granulosus | endoplasmin | 0.0025 | 0.0195 | 0.0181 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0025 | 0.0195 | 0.0181 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0032 | 0.0329 | 0.9647 |
Plasmodium vivax | SET domain protein, putative | 0.0059 | 0.0886 | 0.7765 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0032 | 0.034 | 0.0279 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0704 | 0.0797 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1137 | 0.1204 |
Leishmania major | pyruvate kinase | 0.0032 | 0.034 | 0.1667 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0032 | 0.0329 | 0.0281 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0181 | 0.2243 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0083 | 0.0069 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0083 | 0.0069 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0032 | 0.034 | 0.0279 |
Onchocerca volvulus | 0.0071 | 0.1137 | 0.1141 | |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1137 | 0.1204 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0083 | 0.0094 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0083 | 0.0094 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.2572 | 0.2561 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0771 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0052 | 0.0758 | 0.6626 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0181 | 0.0205 |
Loa Loa (eye worm) | endoplasmin | 0.0032 | 0.0329 | 0.0281 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1137 | 0.115 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.014 | 0.2572 | 0.2561 |
Loa Loa (eye worm) | pyruvate kinase | 0.0032 | 0.034 | 0.0294 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.0329 | 0.2504 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0071 | 0.1137 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.1137 | 0.1065 |
Echinococcus granulosus | heat shock protein 90 | 0.0032 | 0.0329 | 0.0315 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.014 | 0.2572 | 0.2909 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0025 | 0.0195 | 0.0144 |
Mycobacterium leprae | conserved hypothetical protein | 0.0071 | 0.1137 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0704 | 0.0691 |
Trichomonas vaginalis | set domain proteins, putative | 0.0465 | 0.9319 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0704 | 0.0691 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0032 | 0.034 | 0.0385 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0071 | 0.1137 | 0.1065 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.034 | 0.0294 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0745 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0886 | 0.0873 |
Echinococcus multilocularis | pyruvate kinase | 0.0025 | 0.0199 | 0.0185 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0052 | 0.0758 | 0.6037 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.0329 | 0.2504 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0032 | 0.0329 | 0.2803 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.0329 | 0.0315 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0032 | 0.034 | 0.2906 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0083 | 0.0094 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0032 | 0.034 | 0.1546 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0745 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0032 | 0.034 | 0.1667 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0083 | 0.0069 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0052 | 0.0758 | 0.0637 |
Mycobacterium ulcerans | beta-lactamase | 0.0071 | 0.1137 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.014 | 0.2572 | 0.2909 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0083 | 0.0094 |
Loa Loa (eye worm) | beta-lactamase | 0.0071 | 0.1137 | 0.1204 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0083 | 0.0094 |
Plasmodium falciparum | endoplasmin, putative | 0.0019 | 0.0074 | 0.0807 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0059 | 0.0886 | 0.0873 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0181 | 0.1486 |
Plasmodium falciparum | pyruvate kinase | 0.0032 | 0.034 | 0.4385 |
Brugia malayi | RNA binding protein | 0.0278 | 0.5441 | 0.6154 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0886 | 0.0873 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0032 | 0.0329 | 0.1547 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0025 | 0.0195 | 0.1259 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1137 | 0.1204 |
Plasmodium vivax | hypothetical protein, conserved | 0.0071 | 0.1137 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0071 | 0.1137 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0071 | 0.1137 | 0.1124 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0704 | 0.0691 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.6626 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0399 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0025 | 0.0195 | 0.0181 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0083 | 0.0094 |
Echinococcus multilocularis | tar DNA binding protein | 0.0278 | 0.5441 | 0.5434 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Chlamydia trachomatis | pyruvate kinase | 0.0032 | 0.034 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0025 | 0.0195 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.014 | 0.2572 | 0.2561 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0083 | 0.0069 |
Mycobacterium leprae | Probable lipase LipE | 0.0071 | 0.1137 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0032 | 0.0329 | 0.7309 |
Schistosoma mansoni | tar DNA-binding protein | 0.0278 | 0.5441 | 0.5434 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0083 | 0.0069 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0032 | 0.034 | 0.0279 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.0329 | 0.0315 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0083 | 0.0069 |
Plasmodium vivax | pyruvate kinase, putative | 0.0032 | 0.034 | 0.2906 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0052 | 0.0758 | 0.6486 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.1137 | 0.115 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0059 | 0.0886 | 0.0873 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0181 | 0.2243 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0032 | 0.0329 | 0.2504 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0399 | 0.0386 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.014 | 0.2572 | 0.2561 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0083 | 0.0094 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1137 | 0.1204 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0886 | 0.0917 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0083 | 0.0069 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0181 | 0.1132 |
Echinococcus granulosus | tar DNA binding protein | 0.0278 | 0.5441 | 0.5434 |
Echinococcus granulosus | GPCR family 2 | 0.014 | 0.2572 | 0.2561 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0083 | 0.0069 |
Giardia lamblia | Grp94/Hsp90 | 0.0025 | 0.0195 | 0.5535 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0399 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0278 | 0.5441 | 0.5434 |
Loa Loa (eye worm) | pyruvate kinase | 0.0032 | 0.034 | 0.0294 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.2572 | 0.2561 |
Onchocerca volvulus | 0.0071 | 0.1137 | 0.1141 | |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0032 | 0.034 | 0.0288 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0083 | 0.0069 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0745 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0071 | 0.1137 | 0.1204 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Schistosoma mansoni | tar DNA-binding protein | 0.0278 | 0.5441 | 0.5434 |
Brugia malayi | Endoplasmin precursor | 0.0032 | 0.0329 | 0.0372 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0399 | 0.0386 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0025 | 0.0195 | 0.1259 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0071 | 0.1137 | 0.1065 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0052 | 0.0758 | 1 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0032 | 0.0329 | 0.1547 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0408 | 0.8148 | 0.9209 |
Loa Loa (eye worm) | hypothetical protein | 0.0442 | 0.8841 | 1 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0023 | 0.0138 | 0.0062 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.1137 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0059 | 0.0886 | 0.0873 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0083 | 0.0094 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0083 | 0.0094 |
Loa Loa (eye worm) | pyruvate kinase | 0.0032 | 0.034 | 0.0294 |
Plasmodium vivax | heat shock protein 86, putative | 0.0032 | 0.0329 | 0.2803 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.5939 | 0.6687 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1137 | 0.115 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | Pre-SET motif family protein | 0.0059 | 0.0886 | 0.1002 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.1137 | 0.1065 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1137 | 0.115 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.1137 | 0.1286 |
Echinococcus multilocularis | endoplasmin | 0.0025 | 0.0195 | 0.0181 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0052 | 0.0758 | 0.6037 |
Echinococcus multilocularis | GPCR, family 2 | 0.014 | 0.2572 | 0.2561 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.209 | 0.2292 |
Treponema pallidum | heat shock protein 90 | 0.0025 | 0.0195 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0083 | 0.0094 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0071 | 0.1137 | 0.1065 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0083 | 0.0094 |
Schistosoma mansoni | tar DNA-binding protein | 0.0278 | 0.5441 | 0.5434 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.0329 | 0.0315 |
Leishmania major | pyruvate kinase | 0.0032 | 0.034 | 0.1667 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0025 | 0.0195 | 0.5535 |
Mycobacterium ulcerans | pyruvate kinase | 0.0032 | 0.034 | 0.1546 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.209 | 0.2292 |
Giardia lamblia | Pyruvate kinase | 0.0032 | 0.034 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0071 | 0.1137 | 0.1065 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0083 | 0.0094 |
Plasmodium falciparum | heat shock protein 90 | 0.0032 | 0.0329 | 0.423 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.209 | 0.2364 |
Toxoplasma gondii | ABC1 family protein | 0.0071 | 0.1137 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0745 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0442 | 0.8841 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0181 | 0.1132 |
Schistosoma mansoni | tar DNA-binding protein | 0.0278 | 0.5441 | 0.5434 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0302 | 0.5939 | 0.6718 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0083 | 0.0069 |
Loa Loa (eye worm) | TAR-binding protein | 0.0278 | 0.5441 | 0.6118 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.1137 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0704 | 0.0691 |
Echinococcus granulosus | heat shock protein 90 | 0.0025 | 0.0195 | 0.0181 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.1137 | 0.1124 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0071 | 0.1137 | 0.1124 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.2572 | 0.2561 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0452 | 0.9042 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0302 | 0.5939 | 0.5933 |
Loa Loa (eye worm) | RNA binding protein | 0.0278 | 0.5441 | 0.6118 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0083 | 0.0069 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.0329 | 0.0275 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0278 | 0.5441 | 0.6154 |
Trichomonas vaginalis | heat shock protein, putative | 0.0025 | 0.0195 | 0.013 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0083 | 0.0069 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0071 | 0.1137 | 1 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0032 | 0.034 | 0.1667 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0052 | 0.0758 | 0.6037 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.1137 | 0.115 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0059 | 0.0886 | 0.7765 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0083 | 0.0094 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0083 | 0.0069 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0841 | 0.0828 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0083 | 0.0069 |
Onchocerca volvulus | 0.0059 | 0.0886 | 0.0869 | |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Echinococcus granulosus | pyruvate kinase | 0.0032 | 0.034 | 0.0327 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.014 | 0.2572 | 0.2842 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0083 | 0.0069 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0083 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1137 | 0.1204 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0083 | 0.0094 |
Echinococcus multilocularis | heat shock protein | 0.0032 | 0.0329 | 0.0315 |
Brugia malayi | Pre-SET motif family protein | 0.0408 | 0.8148 | 0.9216 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0704 | 0.0691 |
Trichomonas vaginalis | heat shock protein, putative | 0.0025 | 0.0195 | 0.013 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0399 | 1 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0032 | 0.034 | 0.0288 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0745 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0083 | 0.0094 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0399 | 0.0386 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0032 | 0.034 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0181 | 0.0112 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.0329 | 0.1547 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1137 | 0.1204 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0083 | 0.0094 |
Mycobacterium ulcerans | lipase LipD | 0.0071 | 0.1137 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0052 | 0.0758 | 0.0858 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.014 | 0.2572 | 0.2561 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0399 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0032 | 0.0329 | 0.7309 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0083 | 0.0069 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0329 | 0.1547 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0399 | 0.0452 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.2572 | 0.2561 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0083 | 0.0094 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0704 | 0.0709 |
Echinococcus multilocularis | pyruvate kinase | 0.0032 | 0.034 | 0.0327 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0052 | 0.0758 | 0.6486 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0083 | 0.0094 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.1137 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.1137 | 0.1124 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0704 | 0.0691 |
Schistosoma mansoni | pyruvate kinase | 0.0032 | 0.034 | 0.0327 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.1137 | 0.1286 |
Plasmodium vivax | endoplasmin, putative | 0.0032 | 0.0329 | 0.2803 |
Onchocerca volvulus | 0.0465 | 0.9319 | 1 | |
Schistosoma mansoni | pyruvate kinase | 0.0032 | 0.034 | 0.0327 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0032 | 0.034 | 0.2611 |
Onchocerca volvulus | 0.0071 | 0.1137 | 0.1141 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0083 | 0.0094 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.0329 | 0.2504 |
Mycobacterium ulcerans | hypothetical protein | 0.0071 | 0.1137 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0083 | 0.0069 |
Brugia malayi | beta-lactamase | 0.0071 | 0.1137 | 0.1286 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0059 | 0.0886 | 0.0873 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 23 uM | Inhibition of PTP1B | ChEMBL. | 19783142 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.