Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.1014 | 0.1014 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0081 | 0.0081 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.1014 | 0.1014 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.032 | 0.2267 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.141 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0437 | 0.0598 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0081 | 0.0081 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.1253 | 0.8891 |
Brugia malayi | MH1 domain containing protein | 0.0024 | 0.0299 | 0.0306 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.032 | 0.2267 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0127 | 0.3316 | 0.3316 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0081 | 0.0083 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0089 | 0.2191 | 0.8837 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.074 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0349 | 0.9758 | 1 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.1697 | 0.2323 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0172 | 0.0176 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.074 | 0.0759 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0067 | 0.1554 | 0.1554 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0172 | 0.0172 |
Echinococcus multilocularis | lamin | 0.0139 | 0.3641 | 0.3641 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0074 | 0.1768 | 0.1744 |
Schistosoma mansoni | Smad4 | 0.0024 | 0.0299 | 0.0409 |
Schistosoma mansoni | intermediate filament proteins | 0.0139 | 0.3641 | 0.4985 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.1778 | 0.2434 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0081 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0526 | 0.046 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0079 | 0.1921 | 0.263 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0081 | 0.0081 |
Entamoeba histolytica | hypothetical protein | 0.0079 | 0.1921 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0081 | 0.0081 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0081 | 0.0081 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.0081 | 0.0571 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.074 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.1014 | 0.0965 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0138 | 0.3614 | 0.4948 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0024 | 0.0299 | 0.0299 |
Onchocerca volvulus | 0.0052 | 0.1129 | 0.2944 | |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.074 | 1 |
Brugia malayi | RNA binding protein | 0.0075 | 0.1778 | 0.1822 |
Schistosoma mansoni | smad | 0.0024 | 0.0299 | 0.0409 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.0299 | 0.0409 |
Trichomonas vaginalis | glutaminase, putative | 0.0264 | 0.7304 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.1014 | 0.1014 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.074 | 0.0682 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0172 | 0.0235 |
Echinococcus multilocularis | Smad4 | 0.0024 | 0.0299 | 0.0299 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0172 | 0.0235 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0024 | 0.0299 | 0.0226 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0099 | 0.248 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0172 | 0.2317 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.0081 | 0.1088 |
Loa Loa (eye worm) | intermediate filament protein | 0.0139 | 0.3641 | 0.3679 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.032 | 0.2267 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0779 | 0.1066 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0081 | 0.0571 |
Echinococcus granulosus | Smad4 | 0.0024 | 0.0299 | 0.0299 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0081 | 0.0083 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0437 | 0.0598 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 0.3316 | 0.454 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0172 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0138 | 0.3614 | 0.4948 |
Onchocerca volvulus | 0.0032 | 0.0526 | 0.125 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Entamoeba histolytica | hypothetical protein | 0.0079 | 0.1921 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0024 | 0.0299 | 0.0409 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.0755 | 0.0755 |
Loa Loa (eye worm) | TAR-binding protein | 0.0075 | 0.1778 | 0.1754 |
Leishmania major | trypanothione reductase | 0.0039 | 0.074 | 0.525 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0172 | 0.0172 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.074 | 0.0682 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0868 | 0.1188 |
Brugia malayi | Smad1 | 0.0024 | 0.0299 | 0.0306 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0081 | 0.0571 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Schistosoma mansoni | lamin | 0.0139 | 0.3641 | 0.4985 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0172 | 0.2317 |
Onchocerca volvulus | 0.0139 | 0.3641 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0081 | 0.0571 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0868 | 0.2211 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0079 | 0.1921 | 0.1921 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0127 | 0.3316 | 0.3316 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0075 | 0.1778 | 0.1822 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0089 | 0.2191 | 0.8837 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.141 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0089 | 0.2191 | 0.8837 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.141 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.1697 | 0.2323 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.074 | 0.525 |
Onchocerca volvulus | 0.0139 | 0.3641 | 1 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.032 | 0.2267 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0081 | 0.0571 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.1697 | 0.2323 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.1129 | 0.1545 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.074 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0075 | 0.1778 | 0.1754 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0089 | 0.2191 | 0.8837 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0081 | 0.011 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0172 | 0.0692 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0349 | 0.9758 | 1 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.141 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0172 | 0.1217 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0172 | 0.1217 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.032 | 0.4318 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1129 | 0.1083 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0172 | 0.2317 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0067 | 0.1554 | 0.1554 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.1778 | 0.2434 |
Leishmania major | cysteine peptidase A (CPA) | 0.0016 | 0.0081 | 0.0571 |
Loa Loa (eye worm) | Smad1 | 0.0024 | 0.0299 | 0.0226 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.1024 | 0.7264 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.1554 | 0.1523 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0081 | 0.011 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0172 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Brugia malayi | glutathione reductase | 0.0039 | 0.074 | 0.0759 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0024 | 0.0299 | 0.0299 |
Echinococcus granulosus | intermediate filament protein | 0.0139 | 0.3641 | 0.3641 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0138 | 0.3614 | 0.3614 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0081 | 0.1088 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0081 | 0.0571 |
Echinococcus multilocularis | tar DNA binding protein | 0.0075 | 0.1778 | 0.1778 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.0299 | 0.0409 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Toxoplasma gondii | cathepsin CPL | 0.0016 | 0.0081 | 0.1088 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0779 | 0.0722 |
Brugia malayi | intermediate filament protein | 0.0139 | 0.3641 | 0.3731 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0099 | 0.248 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0779 | 0.1961 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0081 | 0.0083 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.1014 | 0.1389 |
Echinococcus granulosus | tar DNA binding protein | 0.0075 | 0.1778 | 0.1778 |
Brugia malayi | hypothetical protein | 0.0024 | 0.032 | 0.0328 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.074 | 0.2985 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0139 | 0.3641 | 0.3731 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0081 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.032 | 0.0247 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.1778 | 0.2434 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0172 | 0.1217 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0081 | 0.0081 |
Echinococcus granulosus | geminin | 0.0175 | 0.4689 | 0.4689 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0072 | 0.1697 | 0.167 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.1697 | 0.1697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.141 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0024 | 0.0299 | 0.0299 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.1697 | 0.1697 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0024 | 0.0299 | 0.0299 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0081 | 0.0081 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.0081 | 0.1088 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0172 | 0.0235 |
Schistosoma mansoni | glutaminase | 0.0264 | 0.7304 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0264 | 0.7304 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0264 | 0.7304 | 0.7485 |
Loa Loa (eye worm) | glutaminase 2 | 0.0264 | 0.7304 | 0.7464 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0081 | 0.0083 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0172 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.1014 | 0.1389 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3641 | 0.3679 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.074 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.074 | 0.525 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0172 | 0.1217 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.1697 | 0.1697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.1014 | 0.104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0079 | 0.1921 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.0081 | 0.1088 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0172 | 0.0494 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.032 | 0.4318 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.4689 | 0.642 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0081 | 0.0083 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0081 | 0.1088 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0081 | 0.0081 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.032 | 0.4318 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.141 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.0299 | 0.0409 |
Echinococcus granulosus | smad | 0.0024 | 0.0299 | 0.0299 |
Brugia malayi | MH2 domain containing protein | 0.0024 | 0.0299 | 0.0306 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0089 | 0.2191 | 0.8837 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.0755 | 0.0755 |
Brugia malayi | Heterochromatin protein 1 | 0.0072 | 0.1697 | 0.1739 |
Echinococcus granulosus | lamin dm0 | 0.0139 | 0.3641 | 0.3641 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0099 | 0.248 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Echinococcus multilocularis | smad | 0.0024 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0024 | 0.0299 | 0.0226 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0172 | 0.0235 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.1778 | 0.2434 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0074 | 0.1768 | 0.1812 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.148 | 0.1446 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0172 | 0.0094 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Entamoeba histolytica | hypothetical protein | 0.0079 | 0.1921 | 1 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.1697 | 0.2323 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0075 | 0.1778 | 0.1754 |
Echinococcus multilocularis | lamin dm0 | 0.0139 | 0.3641 | 0.3641 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.1697 | 0.1697 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0172 | 0.0235 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.1014 | 0.1014 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0139 | 0.3641 | 0.3679 |
Brugia malayi | TAR-binding protein | 0.0075 | 0.1778 | 0.1822 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.3567 | 0.3603 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.148 | 0.1446 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.141 | 1 |
Schistosoma mansoni | lamin | 0.0139 | 0.3641 | 0.4985 |
Brugia malayi | MH2 domain containing protein | 0.0024 | 0.0299 | 0.0306 |
Brugia malayi | MH2 domain containing protein | 0.0349 | 0.9758 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.4689 | 0.642 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.1014 | 0.1389 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0779 | 0.1066 |
Echinococcus multilocularis | musashi | 0.0139 | 0.3641 | 0.3641 |
Echinococcus multilocularis | geminin | 0.0175 | 0.4689 | 0.4689 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Echinococcus granulosus | lamin | 0.0139 | 0.3641 | 0.3641 |
Brugia malayi | MH1 domain containing protein | 0.0024 | 0.0299 | 0.0306 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0779 | 0.0798 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.1778 | 0.2434 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0067 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.1921 | 0.263 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.032 | 0.4318 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1921 | 0.1968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0081 | 0.011 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0099 | 0.248 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0089 | 0.2191 | 0.8837 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0079 | 0.1921 | 0.1921 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0868 | 0.1188 |
Loa Loa (eye worm) | glutaminase | 0.0264 | 0.7304 | 0.7464 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | > 30 uM | Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells assessed as calcium flux by FLIPR assay | ChEMBL. | 19515567 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.