Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.065 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6567 | 0.6567 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1131 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.065 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.065 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.6567 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.6567 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.024 | 0.024 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.4688 | 0.703 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0339 | 0.0339 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.1168 | 0.1168 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.1168 | 0.2229 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.6567 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1168 | 0.1467 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.1168 | 0.2229 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4403 | 0.4403 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.024 | 0.024 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1131 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.1168 | 0.1168 |
Onchocerca volvulus | 0.0032 | 0.4403 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6567 | 0.6567 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.1168 | 0.2229 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0956 | 0.1131 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6567 | 0.6567 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.024 | 0.024 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0339 | 0.0157 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.8869 | 0.5 |
Onchocerca volvulus | 0.0011 | 0.1168 | 0.2229 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.1168 | 0.1168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0127 | 0.0127 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.024 | 0.024 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.658 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.6567 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.4688 | 0.703 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0339 | 0.0339 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.658 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.6567 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0157 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.1168 | 0.1168 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0936 | 0.11 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.065 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.1168 | 0.1168 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.024 | 0.024 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.1168 | 0.1168 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.6567 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.