Detailed information for compound 1078410

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 694.708 | Formula: C38H36F6N4O2
  • H donors: 0 H acceptors: 2 LogP: 7.37 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCN(CCN(C(=O)Cn1c(CCc2c(F)ccc(c2F)F)nc(=O)c2c1cccc2)Cc1ccc(cc1)c1ccc(cc1)C(F)(F)F)CC
  • InChi: 1S/C38H36F6N4O2/c1-3-46(4-2)21-22-47(23-25-9-11-26(12-10-25)27-13-15-28(16-14-27)38(42,43)44)35(49)24-48-33-8-6-5-7-30(33)37(50)45-34(48)20-17-29-31(39)18-19-32(40)36(29)41/h5-16,18-19H,3-4,17,20-24H2,1-2H3
  • InChiKey: PWLGDLXIDVHFPY-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0224 0.0436
Schistosoma mansoni axis inhibition protein axin 0.0045 0.007 0.0082
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0101 0.0179
Mycobacterium tuberculosis Probable dehydrogenase 0.0238 0.0612 0.4992
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.007 0.0131
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0004
Schistosoma mansoni tubulin subunit beta 0.183 0.5093 0.6137
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Plasmodium falciparum ataxin-2 like protein, putative 0.0111 0.0255 0.0482
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0064 0.0123 0.0237
Treponema pallidum fructose-bisphosphate aldolase 0.0311 0.0819 0.6664
Giardia lamblia Kinase, CMGC CLK 0.0068 0.0134 0.0202
Echinococcus granulosus caspase 3 0.008 0.0167 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0166 0.0323
Brugia malayi 6-phosphofructokinase 0.0118 0.0276 0.0535
Plasmodium vivax metacaspase 1, putative 0.0029 0.0025 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0033 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0181
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.01 0.0224 0.0393
Trichomonas vaginalis tubulin epsilon chain, putative 0.183 0.5093 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0153 0.0375 0.0736
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0072 0.0145 0.0664
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0118 0.0275 0.2229
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0031 0.0021
Brugia malayi hypothetical protein 0.0879 0.2418 0.4743
Giardia lamblia Alpha-tubulin 0.1386 0.3845 0.7534
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.0031 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0072 0.0145 0.0279
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.0031 0.0042
Schistosoma mansoni steroid hormone receptor ad4bp 0.0072 0.0145 0.0173
Echinococcus granulosus TGF beta signal transducer SmadC 0.0044 0.0068 0.0071
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0085 0.0182 0.0311
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0059 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0145 0.0173
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0293 0.2377
Onchocerca volvulus 0.0068 0.0134 0.0614
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0057 0.0058
Loa Loa (eye worm) tubulin alpha chain 0.1386 0.3845 0.7549
Echinococcus granulosus CREB binding protein 0.0127 0.0301 0.0352
Trichomonas vaginalis tubulin alpha chain, putative 0.183 0.5093 1
Leishmania major ATP-dependent phosphofructokinase 0.0118 0.0275 0.0521
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.001 0.0016
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.007 0.0082
Entamoeba histolytica hypothetical protein 0.0197 0.0496 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0181
Entamoeba histolytica hypothetical protein 0.0045 0.007 0.0118
Brugia malayi MH1 domain containing protein 0.0025 0.0012 0.0017
Schistosoma mansoni lipoxygenase 0.0794 0.2179 0.2624
Loa Loa (eye worm) hypothetical protein 0.0101 0.0226 0.0443
Brugia malayi Tubulin alpha chain 0.0455 0.1222 0.2395
Onchocerca volvulus Cell death protein 3 homolog 0.0029 0.0025 0.01
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0038 0.0034
Trypanosoma brucei beta tubulin 0.183 0.5093 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Trypanosoma brucei zeta tubulin 0.0771 0.2114 0.4136
Onchocerca volvulus Putative organic anion transporter 0.0094 0.0206 0.0951
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0101 0.0803
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0068 0.0134 0.026
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0069 0.0132
Loa Loa (eye worm) MH2 domain-containing protein 0.0044 0.0068 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0134 0.026
Trichomonas vaginalis tubulin beta chain, putative 0.1386 0.3845 0.7548
Echinococcus granulosus CREB binding protein 0.0034 0.0038 0.0035
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0031 0.0021
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.001 0.0016
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0035 0.004 0.0046
Trypanosoma cruzi tubulin delta chain 0.0644 0.1756 0.3415
Trichomonas vaginalis tubulin beta chain, putative 0.183 0.5093 1
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0057 0.0106
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0037 0.0048
Leishmania major beta tubulin 0.183 0.5093 1
Brugia malayi Tubulin beta chain 0.0455 0.1222 0.2395
Trichomonas vaginalis tubulin alpha chain, putative 0.101 0.2787 0.5469
Echinococcus multilocularis Tubulin alpha 1 chain 0.1386 0.3845 0.3839
Echinococcus granulosus tubulin subunit TubB 0.1386 0.3845 0.4628
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0047 0.0076 0.0148
Loa Loa (eye worm) cytochrome P450 family protein 0.0153 0.0375 0.0736
Echinococcus multilocularis caspase 0.0109 0.025 0.024
Echinococcus multilocularis beta adrenergic receptor kinase 0.0047 0.0076 0.0066
Schistosoma mansoni cpg binding protein 0.0128 0.0304 0.0364
Echinococcus multilocularis mitogen activated protein kinase 3 0.0165 0.0408 0.0399
Echinococcus granulosus FTZ F1 alpha 0.0072 0.0145 0.0164
Schistosoma mansoni tubulin subunit beta 0.183 0.5093 0.6137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0057 0.0048
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Brugia malayi tubulin alpha-2 chain 0.1386 0.3845 0.7548
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0013 0.0165
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0031 0.0054
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0644 0.1756 0.3445
Leishmania major cytochrome p450-like protein 0.007 0.0139 0.0254
Echinococcus multilocularis tubulin alpha chain 0.1386 0.3845 0.3839
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0033 0.0002
Echinococcus multilocularis CREB binding protein 0.0034 0.0038 0.0029
Leishmania major beta tubulin 0.183 0.5093 1
Brugia malayi Cell death protein 3 precursor 0.0029 0.0025 0.0042
Leishmania major beta tubulin 0.183 0.5093 1
Loa Loa (eye worm) hypothetical protein 0.0399 0.1067 0.2095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0072 0.0145 0.0285
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0145 0.0173
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0556 0.1507 0.2956
Trichomonas vaginalis taga, putative 0.0024 0.001 0.0016
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0068 0.0134 0.0215
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0112
Brugia malayi Doublecortin family protein 0.0212 0.0538 0.1051
Echinococcus multilocularis lipoxygenase domain containing protein 0.0212 0.0538 0.0529
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0072 0.0145 0.0285
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0112
Echinococcus multilocularis 0.0066 0.0128 0.0119
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0033 0.1372
Mycobacterium tuberculosis Cell division protein FtsZ 0.0455 0.1222 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Loa Loa (eye worm) BEN-1 protein 0.183 0.5093 1
Trichomonas vaginalis tubulin beta chain, putative 0.1386 0.3845 0.7548
Echinococcus multilocularis lysine specific demethylase 5A 0.0066 0.0127 0.0118
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0085 0.0182 0.0358
Echinococcus multilocularis tubulin delta chain 0.0455 0.1222 0.1214
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0044 0.0083
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.0371 0.3014
Onchocerca volvulus 0.0116 0.0268 0.124
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0137
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0275 0.0329
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0057 0.0051
Brugia malayi hypoxia-induced factor 1 0.0811 0.2226 0.4367
Brugia malayi prostaglandin transporter 0.0094 0.0206 0.0399
Schistosoma mansoni hypothetical protein 0.005 0.0083 0.0098
Plasmodium falciparum LCCL domain-containing protein 0.0212 0.0538 0.1039
Echinococcus granulosus nuclear factor of activated T cells 5 0.0082 0.0174 0.0199
Brugia malayi MH2 domain containing protein 0.0653 0.1781 0.3493
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0072 0.0145 0.0279
Echinococcus granulosus neuropeptide receptor A26 0.1014 0.2798 0.3365
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0165 0.0408 0.0756
Echinococcus granulosus cpg binding protein 0.0128 0.0304 0.0356
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0101 0.0226 0.044
Echinococcus granulosus Protein patched homolog 1 0.0092 0.0202 0.0233
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Leishmania major beta tubulin 0.183 0.5093 1
Trypanosoma brucei zeta tubulin, putative 0.0771 0.2114 0.4136
Leishmania major beta tubulin 0.183 0.5093 1
Plasmodium falciparum metacaspase 1 0.0029 0.0025 0.0029
Loa Loa (eye worm) isocitrate dehydrogenase 0.0035 0.004 0.0078
Entamoeba histolytica tubulin alpha-1 chain 0.1386 0.3845 0.7544
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0068 0.0134 0.026
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0069 0.0132
Brugia malayi hypothetical protein 0.0215 0.0548 0.107
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0111 0.0214
Schistosoma mansoni coup transcription factor 0.0072 0.0145 0.0173
Brugia malayi Intermediate filament tail domain containing protein 0.0116 0.0268 0.052
Loa Loa (eye worm) hypothetical protein 0.083 0.2281 0.4478
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0037 0.0028
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.007 0.0139 0.1116
Brugia malayi sodium-independent organic anion transporter family protein 0.0094 0.0206 0.0399
Brugia malayi cytoplasmic intermediate filament protein 0.0062 0.0117 0.0223
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.007 0.0073
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0044 0.0067
Schistosoma mansoni polycystin 1-related 0.0212 0.0538 0.0646
Trichomonas vaginalis adenylate cyclase, putative 0.0068 0.0134 0.026
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0033 0.1372
Loa Loa (eye worm) hypothetical protein 0.0212 0.0538 0.1057
Brugia malayi secreted modular calcium-binding protein 1 0.0064 0.0123 0.0234
Schistosoma mansoni nuclear receptor 0.0031 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0112
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0064 0.0123 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0069
Brugia malayi hypothetical protein 0.0094 0.0206 0.0399
Entamoeba histolytica hypothetical protein 0.0025 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Mycobacterium ulcerans cell division protein FtsZ 0.0455 0.1222 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0025 0.0045
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.001 0.0016
Brugia malayi intermediate filament protein 0.0116 0.0268 0.052
Echinococcus granulosus Polycystic kidney disease protein 0.0212 0.0538 0.0638
Trypanosoma brucei alpha tubulin 0.1386 0.3845 0.7543
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.004 0.003
Onchocerca volvulus 0.0116 0.0268 0.124
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.007 0.0082
Trypanosoma cruzi epsilon tubulin, putative 0.104 0.2872 0.5617
Giardia lamblia Delta tubulin 0.0455 0.1222 0.2353
Echinococcus granulosus lamin dm0 0.0116 0.0268 0.0312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0057 0.0444
Echinococcus granulosus Tubulin beta 2C chain 0.183 0.5093 0.6134
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0101 0.0803
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.0371 0.3014
Loa Loa (eye worm) hypothetical protein 0.0092 0.0202 0.0398
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.007 0.0139 0.1116
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0145 0.0279
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0013 0.0078
Echinococcus multilocularis tubulin alpha chain 0.1386 0.3845 0.3839
Trichomonas vaginalis tubulin beta chain, putative 0.1386 0.3845 0.7548
Loa Loa (eye worm) hypothetical protein 0.0267 0.0693 0.1361
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0031 0.0054
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0072 0.0145 0.0173
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0197 0.0496 0.0487
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0064 0.0123 0.0237
Brugia malayi isocitrate dehydrogenase 0.0035 0.004 0.0072
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0064 0.0123 0.0234
Echinococcus multilocularis expressed conserved protein 0.0202 0.0511 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0045
Brugia malayi ecdysteroid receptor 0.0072 0.0145 0.0279
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Leishmania major gamma-tubulin 0.1041 0.2873 0.5632
Brugia malayi MH2 domain containing protein 0.0044 0.0068 0.0127
Trypanosoma brucei epsilon tubulin 0.104 0.2872 0.5627
Toxoplasma gondii thioredoxin reductase 0.0104 0.0236 0.046
Echinococcus multilocularis neuropeptide receptor A26 0.1014 0.2798 0.2791
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0064 0.0123 0.0234
Schistosoma mansoni caspase-7 (C14 family) 0.0109 0.025 0.0298
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.007 0.0139 0.1116
Schistosoma mansoni alpha tubulin 0.1386 0.3845 0.4632
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0044 0.0042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0264 0.0687 0.5605
Onchocerca volvulus 0.0194 0.0489 0.2275
Onchocerca volvulus Huntingtin homolog 0.0399 0.1067 0.4984
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0293 0.0342
Loa Loa (eye worm) tubulin beta-1 chain 0.183 0.5093 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.015 0.0247
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0062
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0094 0.0206 0.0237
Brugia malayi glutathione reductase 0.0104 0.0236 0.0457
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0192 0.022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0408 0.0756
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.015 0.0295
Loa Loa (eye worm) thioredoxin reductase 0.0104 0.0236 0.0463
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0013 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0202 0.0394
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0075 0.0088
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0134 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Brugia malayi jmjC domain containing protein 0.0073 0.0147 0.0282
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0072 0.0145 0.0173
Echinococcus multilocularis expressed protein 0.0064 0.0123 0.0113
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.015 0.0141
Echinococcus multilocularis aryl hydrocarbon receptor 0.0068 0.0134 0.0125
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0018
Schistosoma mansoni hypothetical protein 0.0197 0.0496 0.0596
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0147 0.0175
Loa Loa (eye worm) hypothetical protein 0.0097 0.0216 0.0424
Entamoeba histolytica hypothetical protein 0.0045 0.007 0.0118
Toxoplasma gondii tubulin, putative 0.003 0.0028 0.0051
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0068 0.0134 0.0263
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0275 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0069
Toxoplasma gondii histone lysine methyltransferase SET1 0.0237 0.0611 0.1196
Trypanosoma brucei alpha tubulin 0.1386 0.3845 0.7543
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0173 0.0321
Entamoeba histolytica tubulin family protein 0.183 0.5093 1
Brugia malayi PXA domain containing protein 0.0045 0.007 0.0131
Echinococcus granulosus ubiquitin specific protease 41 0.0085 0.0182 0.0209
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0013 0.0021
Leishmania major beta tubulin 0.183 0.5093 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0039
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0145 0.0279
Schistosoma mansoni lamin 0.0116 0.0268 0.0321
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0044 0.0062
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0044 0.0039
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0059 0.0059
Leishmania major beta tubulin 0.183 0.5093 1
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0031 0.0035
Echinococcus granulosus aryl hydrocarbon receptor 0.0068 0.0134 0.0151
Onchocerca volvulus 0.0121 0.0285 0.1319
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0044 0.0062
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.0031 0.0022
Toxoplasma gondii transporter, major facilitator family protein 0.0094 0.0206 0.0401
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.007 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0131 0.0254
Schistosoma mansoni tubulin subunit alpha 0.1386 0.3845 0.4632
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0455 0.1222 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0153 0.0375 0.3046
Brugia malayi hypothetical protein 0.0212 0.0538 0.1051
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0033 0.006
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0085 0.0182 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.1222 0.2397
Loa Loa (eye worm) hypothetical protein 0.0089 0.0192 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Schistosoma mansoni patched 1 0.0092 0.0202 0.0242
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Schistosoma mansoni hypothetical protein 0.0212 0.0538 0.0646
Trypanosoma cruzi MFS transporter, putative 0.0094 0.0206 0.0358
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0063 0.0064
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0067
Onchocerca volvulus 0.0089 0.0192 0.0884
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0101 0.0226 0.0217
Plasmodium falciparum tubulin beta chain 0.183 0.5093 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0094 0.0206 0.0399
Trichomonas vaginalis set domain proteins, putative 0.0779 0.2137 0.4193
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0039 0.0057
Brugia malayi Cytochrome P450 family protein 0.007 0.0139 0.0267
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0072 0.0145 0.0164
Brugia malayi F/Y-rich N-terminus family protein 0.0041 0.0057 0.0106
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0275 0.0536
Loa Loa (eye worm) hypothetical protein 0.0399 0.1067 0.2095
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0035 0.004 0.003
Echinococcus multilocularis ecdysone induced protein 78C 0.0072 0.0145 0.0136
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.001 0.0016
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0037 0.0042
Loa Loa (eye worm) phosphofructokinase 0.0118 0.0275 0.054
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Echinococcus multilocularis CREB binding protein 0.0034 0.0038 0.0029
Brugia malayi PAS domain containing protein 0.0262 0.068 0.133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0182
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.015 0.0288
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.01 0.0224 0.042
Mycobacterium leprae Conserved hypothetical protein 0.007 0.0139 0.1116
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.007 0.0133
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0069 0.0129
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0275 0.0521
Brugia malayi nuclear receptor NHR-88 0.0072 0.0145 0.0279
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0085 0.0182 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0182
Echinococcus multilocularis tubulin subunit beta 0.183 0.5093 0.5089
Echinococcus multilocularis beta tubulin 0.183 0.5093 0.5089
Toxoplasma gondii LsmAD domain-containing protein 0.0111 0.0255 0.0498
Trypanosoma brucei beta tubulin 0.183 0.5093 1
Brugia malayi Tubulin gamma chain 0.1041 0.2873 0.5638
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Plasmodium vivax tubulin gamma chain, putative 0.1041 0.2873 0.5632
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0134 0.026
Schistosoma mansoni hypothetical protein 0.0089 0.0193 0.0231
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0016 0.0028
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0082 0.0174 0.0165
Echinococcus granulosus tubulin alpha chain 0.1386 0.3845 0.4628
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0137
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Onchocerca volvulus 0.0103 0.0232 0.1071
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0165 0.0408 0.0797
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Schistosoma mansoni hypothetical protein 0.0926 0.2549 0.307
Trichomonas vaginalis tubulin, putative 0.0485 0.1309 0.2567
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Onchocerca volvulus 0.0215 0.0548 0.2552
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0031 0.0058
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.007 0.0139 0.1116
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0232 0.0449
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0045 0.007 0.0061
Loa Loa (eye worm) transcription factor SMAD2 0.0653 0.1781 0.3497
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0013 0.0005
Brugia malayi Tubulin alpha chain 0.1386 0.3845 0.7548
Schistosoma mansoni regulator of G protein signaling 0.0045 0.007 0.0082
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0072 0.0145 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0072 0.0145 0.0279
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0455 0.1222 0.2397
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0264 0.0687 0.5605
Brugia malayi Pre-SET motif family protein 0.0685 0.1871 0.367
Loa Loa (eye worm) cytochrome P450 0.007 0.0139 0.0274
Trichomonas vaginalis tubulin epsilon chain, putative 0.183 0.5093 1
Leishmania major beta tubulin 0.183 0.5093 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0025 0.0045
Trypanosoma brucei Metacaspase-4 0.0029 0.0025 0.0023
Echinococcus multilocularis CREB binding protein 0.0034 0.0038 0.0029
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0017 0.0028
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0017 0.0028
Echinococcus multilocularis tubulin alpha 1C chain 0.1386 0.3845 0.3839
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0068 0.0134 0.0216
Echinococcus multilocularis sterol regulatory element binding protein 0.0092 0.0202 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Trichomonas vaginalis tubulin beta chain, putative 0.1386 0.3845 0.7548
Brugia malayi steroid hormone receptor 0.0072 0.0145 0.0279
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0057 0.0369
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0031 0.0035
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0165 0.0408 0.0778
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0275 0.0536
Brugia malayi Isocitrate dehydrogenase 0.0035 0.004 0.0072
Echinococcus granulosus lipoxygenase domain containing protein 0.0212 0.0538 0.0638
Brugia malayi Steroid receptor seven-up type 2 0.0072 0.0145 0.0279
Onchocerca volvulus 0.0024 0.001 0.0032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0031 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0145 0.0279
Trypanosoma brucei alpha tubulin 0.1386 0.3845 0.7543
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0094 0.0208 0.024
Echinococcus granulosus Smad4 0.0044 0.0068 0.0071
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0101 0.0803
Brugia malayi Tubulin alpha-2 chain 0.1386 0.3845 0.7548
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0127 0.0151
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.001 0.0016
Schistosoma mansoni tubulin subunit beta 0.183 0.5093 0.6137
Trichomonas vaginalis tubulin gamma chain, putative 0.183 0.5093 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0215 0.0548 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.007 0.0061
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.0031 0.0027
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.005 0.0083 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.007 0.0133
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0238 0.0612 0.4992
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0072 0.0145 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Plasmodium vivax multidomain scavenger receptor, putative 0.0212 0.0538 0.1039
Toxoplasma gondii beta-tubulin, putative 0.183 0.5093 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0085 0.0182 0.0209
Schistosoma mansoni tubulin subunit beta 0.0455 0.1222 0.1471
Brugia malayi Pax transcription factor protein 2 0.0269 0.0699 0.1366
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Echinococcus multilocularis tubulin alpha 3 chain 0.1386 0.3845 0.3839
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0109 0.021
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0031 0.006
Leishmania major beta tubulin 0.183 0.5093 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0261 0.0512
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0181
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0408 0.0797
Echinococcus multilocularis Tubulin beta 2C chain 0.183 0.5093 0.5089
Loa Loa (eye worm) tubulin alpha chain 0.1386 0.3845 0.7549
Loa Loa (eye worm) PXA domain-containing protein 0.0045 0.007 0.0137
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Echinococcus granulosus Tubulin alpha 1 chain 0.1386 0.3845 0.4628
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0166 0.0323
Echinococcus granulosus Tubulin alpha 1 chain 0.1386 0.3845 0.4628
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0068 0.0134 0.0259
Schistosoma mansoni hypothetical protein 0.0089 0.0193 0.0231
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0041 0.0057 0.0067
Brugia malayi hypothetical protein 0.0504 0.1361 0.2667
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0056 0.01 0.0196
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.007 0.0139 0.1116
Echinococcus multilocularis musashi 0.0116 0.0268 0.0259
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.014 0.0228
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.007 0.0073
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.01 0.0224 0.042
Loa Loa (eye worm) hypothetical protein 0.0212 0.0538 0.1057
Trypanosoma brucei alpha tubulin, putative 0.0556 0.1507 0.2941
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0192 0.0371
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Leishmania major protein kinase, putative 0.007 0.014 0.0256
Loa Loa (eye worm) tubulin beta-2A chain 0.183 0.5093 1
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.1222 0.2397
Echinococcus granulosus Regulator of G protein signaling 20 0.0045 0.007 0.0073
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0101 0.0226 0.0217
Toxoplasma gondii beta-1 tubulin, putative 0.183 0.5093 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.014 0.0228
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0072 0.0145 0.0285
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0013 0.0078
Echinococcus granulosus tubulin delta chain 0.0455 0.1222 0.1463
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0031 0.0054
Echinococcus granulosus caspase 2 0.0029 0.0025 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0025 0.0029
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0031 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0134 0.0159
Trichomonas vaginalis abcb9, putative 0.0024 0.001 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0085 0.0182 0.0311
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.007 0.0139 0.1116
Loa Loa (eye worm) hypothetical protein 0.0116 0.0268 0.0526
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.015 0.0179
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0033 0.006
Loa Loa (eye worm) tubulin alpha 2 0.0932 0.2565 0.5037
Echinococcus multilocularis isocitrate dehydrogenase 0.0035 0.004 0.003
Brugia malayi tailless protein 0.0031 0.0031 0.0054
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0116 0.0268 0.0526
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Schistosoma mansoni DNA helicase recq5 0.0032 0.0031 0.0036
Echinococcus granulosus caspase 8 0.0029 0.0025 0.0019
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0173 0.1394
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0072 0.0145 0.0164
Trypanosoma brucei tubulin gamma chain 0.1041 0.2873 0.563
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0037 0.0053
Trypanosoma cruzi alpha tubulin, putative 0.1386 0.3845 0.7537
Leishmania major beta tubulin 0.183 0.5093 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.007 0.0139 0.1116
Brugia malayi Cytochrome P450 family protein 0.0153 0.0375 0.0729
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0024
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0064 0.0123 0.0234
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0293 0.2377
Brugia malayi follicle stimulating hormone receptor 0.0271 0.0705 0.1378
Onchocerca volvulus Huntingtin homolog 0.0399 0.1067 0.4984
Echinococcus granulosus tubulin alpha chain 0.1386 0.3845 0.4628
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0094 0.0206 0.0405
Echinococcus granulosus axis inhibition protein axin 0.0045 0.007 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0072 0.0145 0.0279
Echinococcus granulosus histone lysine methyltransferase setb 0.0101 0.0226 0.0261
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Brugia malayi nuclear receptor RXR 0.0041 0.0057 0.0106
Brugia malayi MH2 domain containing protein 0.0044 0.0068 0.0127
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0094 0.0206 0.0197
Leishmania major beta tubulin 0.183 0.5093 1
Plasmodium falciparum metacaspase-like protein 0.0029 0.0025 0.0029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.004 0.003
Plasmodium falciparum tubulin gamma chain 0.1041 0.2873 0.5632
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0485 0.1307 0.2564
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0068 0.0134 0.0216
Plasmodium falciparum tubulin delta chain, putative 0.0455 0.1222 0.2385
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0275 0.0521
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0044 0.0062
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.007 0.0139 0.1116
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0057 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Loa Loa (eye worm) doublecortin family protein 0.0212 0.0538 0.1057
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0033 0.0163
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0137
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.0819 0.1591
Echinococcus granulosus caspase 0.0109 0.025 0.029
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.001 0.0016
Echinococcus multilocularis Tubulin beta 2C chain 0.183 0.5093 0.5089
Loa Loa (eye worm) tubulin alpha-3 chain 0.083 0.2281 0.4478
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0037 0.0073
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.007 0.0139 0.1116
Echinococcus granulosus Tubulin beta 2C chain 0.183 0.5093 0.6134
Brugia malayi hypothetical protein 0.0072 0.0145 0.0277
Trichomonas vaginalis ABC transporter, putative 0.0024 0.001 0.0016
Leishmania major delta tubulin, putative 0.0644 0.1756 0.3434
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0072 0.0145 0.0173
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.007 0.0139 0.1116
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0111 0.0214
Echinococcus granulosus jun protein 0.0274 0.0713 0.0849
Echinococcus granulosus dual specificity protein kinase clk2 0.0068 0.0134 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0274 0.0713 0.0849
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0031 0.0021
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0932 0.2565 0.5035
Brugia malayi Tubulin beta chain 0.0556 0.1507 0.2954
Echinococcus granulosus mixed lineage leukemia protein mll 0.0034 0.0038 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0137
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0044 0.0083
Echinococcus granulosus agrin 0.0064 0.0123 0.0137
Echinococcus multilocularis regulator of G protein signaling 0.0045 0.007 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.007 0.0139 0.1116
Echinococcus granulosus tubulin subunit beta 0.183 0.5093 0.6134
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.004 0.0074
Schistosoma mansoni follistatin 0.0064 0.0123 0.0146
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0031 0.0026
Plasmodium vivax glutathione reductase, putative 0.0104 0.0236 0.0444
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0057 0.0093
Giardia lamblia Alpha-tubulin 0.1386 0.3845 0.7534
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0031 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Schistosoma mansoni tubulin subunit alpha 0.0455 0.1222 0.1471
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.007 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0145 0.0164
Echinococcus granulosus Tubulin beta 2C chain 0.183 0.5093 0.6134
Schistosoma mansoni intermediate filament proteins 0.0116 0.0268 0.0321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0125 0.0242
Plasmodium falciparum thioredoxin reductase 0.0104 0.0236 0.0444
Onchocerca volvulus 0.0094 0.0206 0.0951
Schistosoma mansoni hypothetical protein 0.007 0.0139 0.0166
Loa Loa (eye worm) tubulin gamma chain 0.1041 0.2873 0.5641
Loa Loa (eye worm) hypothetical protein 0.0113 0.0262 0.0514
Onchocerca volvulus Putative organic anion transporter 0.0094 0.0206 0.0951
Echinococcus multilocularis tubulin alpha 1C chain 0.1386 0.3845 0.3839
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0068 0.0134 0.026
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.007 0.0139 0.1116
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.007 0.0139 0.1116
Onchocerca volvulus 0.0094 0.0206 0.0951
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0007
Giardia lamblia Beta tubulin 0.183 0.5093 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0197 0.0496 0.0587
Trichomonas vaginalis tubulin, putative 0.0556 0.1507 0.2956
Echinococcus granulosus tubulin alpha 1C chain 0.1386 0.3845 0.4628
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.007 0.0139 0.1116
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.007 0.0061
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0057 0.0088
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0068 0.0134 0.7624
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.007 0.0139 0.0249
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Loa Loa (eye worm) BEN-1 protein 0.183 0.5093 1
Schistosoma mansoni DNA helicase recq1 0.0032 0.0031 0.0036
Trichomonas vaginalis tubulin gamma chain, putative 0.104 0.2872 0.5637
Loa Loa (eye worm) hypothetical protein 0.0879 0.2418 0.4747
Loa Loa (eye worm) CBP-B 0.0143 0.0347 0.0681
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0035 0.004 0.0053
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.007 0.0139 0.1116
Brugia malayi cytochrome P450 0.007 0.0139 0.0267
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.004 0.0053
Trypanosoma cruzi zeta tubulin, putative 0.0771 0.2114 0.4122
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0147 0.0289
Schistosoma mansoni axis inhibition protein axin 0.0045 0.007 0.0082
Brugia malayi hypothetical protein 0.0212 0.0538 0.1051
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0039 0.0073
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.001 0.0001
Trichomonas vaginalis tubulin gamma chain, putative 0.0455 0.1222 0.2397
Schistosoma mansoni cytochrome P450 0.007 0.0139 0.0166
Echinococcus granulosus 6 phosphofructokinase 0.0118 0.0275 0.0321
Onchocerca volvulus 0.0212 0.0538 0.2506
Entamoeba histolytica tubulin family protein 0.183 0.5093 1
Brugia malayi conserved hypotetical protein 0.0031 0.0031 0.0054
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0408 0.0797
Mycobacterium ulcerans endonuclease IV 0.0082 0.0173 0.1394
Loa Loa (eye worm) RecQ helicase 0.0045 0.0069 0.0136
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.001 0.0001
Echinococcus granulosus mitogen activated protein kinase 3 0.0165 0.0408 0.0481
Echinococcus granulosus tubulin beta 1 chain 0.183 0.5093 0.6134
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0031 0.0021
Plasmodium vivax SET domain protein, putative 0.0101 0.0226 0.0424
Loa Loa (eye worm) hypothetical protein 0.0084 0.0178 0.0349
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0238 0.0612 0.4992
Echinococcus multilocularis Tubulin alpha 1 chain 0.1386 0.3845 0.3839
Schistosoma mansoni nuclear hormone receptor 0.0072 0.0145 0.0173
Schistosoma mansoni agrin 0.0064 0.0123 0.0146
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0044 0.0062
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Brugia malayi MH1 domain containing protein 0.0044 0.0068 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0166 0.0323
Trichomonas vaginalis tubulin beta chain, putative 0.0556 0.1507 0.2956
Trypanosoma brucei metacaspase 0.0029 0.0025 0.0023
Echinococcus granulosus tubulin alpha 3 chain 0.1386 0.3845 0.4628
Echinococcus multilocularis thyroid hormone receptor alpha 0.0072 0.0145 0.0136
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0033 0.006
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.001 0.0056
Loa Loa (eye worm) histone methyltransferase 0.0041 0.0059 0.0115
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.004 0.003
Schistosoma mansoni hypothetical protein 0.0089 0.0193 0.0231
Schistosoma mansoni tubulin subunit beta 0.183 0.5093 0.6137
Brugia malayi hypothetical protein 0.0045 0.007 0.0131
Schistosoma mansoni jun-related protein 0.0222 0.0569 0.0684
Leishmania major beta tubulin 0.183 0.5093 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Echinococcus granulosus Niemann Pick C1 protein 0.0307 0.0808 0.0963
Schistosoma mansoni organic anion transporter 0.0094 0.0206 0.0246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0275 0.054
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0013 0.0005
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0037 0.0053
Brugia malayi alpha-tubulin 0.1386 0.3845 0.7548
Schistosoma mansoni ap endonuclease 0.0041 0.0057 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0224 0.0436
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0085 0.0182 0.0352
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0057 0.0113
Echinococcus multilocularis expressed protein 0.0784 0.2148 0.2141
Trichomonas vaginalis abcb9, putative 0.0024 0.001 0.0016
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0079 0.0167 0.0303
Echinococcus multilocularis protein patched 0.0092 0.0202 0.0193
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0275 0.0516
Plasmodium vivax thioredoxin reductase, putative 0.0104 0.0236 0.0444
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0044 0.0337
Schistosoma mansoni hypothetical protein 0.1295 0.3587 0.4322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Brugia malayi hypothetical protein 0.0197 0.0496 0.0968
Echinococcus multilocularis agrin 0.0064 0.0123 0.0113
Loa Loa (eye worm) MH1 domain-containing protein 0.0044 0.0068 0.0133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0039
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0044 0.0067
Echinococcus multilocularis raf serine:threonine protein kinase 0.0047 0.0075 0.0065
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.007 0.0139 0.1116
Giardia lamblia Gamma tubulin 0.1041 0.2873 0.5614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0069
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0165 0.0408 0.0756
Mycobacterium leprae Possible regulatory protein 0.0068 0.0134 0.1076
Trypanosoma cruzi cytochrome p450-like protein, putative 0.007 0.0139 0.0226
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0173 0.1394
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0165 0.0408 0.0782
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0275 0.0329
Loa Loa (eye worm) raf kinase 0.0047 0.0075 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0145 0.0279
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0085 0.0182 0.0218
Echinococcus multilocularis survival motor neuron protein 1 0.0504 0.1361 0.1353
Echinococcus granulosus geminin 0.0926 0.2549 0.3064
Loa Loa (eye worm) hypoxia-induced factor 1 0.0811 0.2226 0.437
Loa Loa (eye worm) hypothetical protein 0.0504 0.1361 0.2672
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0035 0.004 0.0037
Trichomonas vaginalis tubulin alpha chain, putative 0.0556 0.1507 0.2956
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.01 0.0224 0.042
Echinococcus multilocularis peroxisome assembly protein 26 0.1386 0.3845 0.3839
Echinococcus multilocularis Tubulin alpha 1 chain 0.1386 0.3845 0.3839
Plasmodium falciparum tubulin epsilon chain, putative 0.104 0.2872 0.563
Echinococcus granulosus Niemann Pick C1 protein 0.0215 0.0548 0.065
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0068 0.0134 0.0238
Giardia lamblia GTOR 0.01 0.0224 0.038
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0072 0.0145 0.0164
Schistosoma mansoni tubulin subunit epsilon 0.104 0.2872 0.3459
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0044 0.0067
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0033 0.0044
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0037 0.0066
Trypanosoma brucei beta tubulin 0.183 0.5093 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0275 0.0494
Loa Loa (eye worm) hypothetical protein 0.0064 0.0123 0.0241
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0275 0.054
Leishmania major protein kinase, putative 0.0068 0.0134 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0069
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0264 0.0687 0.5605
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0091 0.0178
Trichomonas vaginalis tubulin epsilon chain, putative 0.1386 0.3845 0.7548
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.007 0.0139 0.1116
Onchocerca volvulus 0.0212 0.0538 0.2506
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.007 0.0061
Loa Loa (eye worm) hypothetical protein 0.0215 0.0548 0.1076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0145 0.0279
Schistosoma mansoni rab6-interacting 0.0212 0.0538 0.0646
Echinococcus multilocularis lamin 0.0116 0.0268 0.0259
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0145 0.0136
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0072 0.0145 0.0285
Onchocerca volvulus 0.0094 0.0206 0.0951
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0041 0.0057 0.0112
Echinococcus granulosus lamin 0.0116 0.0268 0.0312
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0033 0.0044
Leishmania major trypanothione reductase 0.0104 0.0236 0.0444
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Schistosoma mansoni regulator of G protein signaling 0.0045 0.007 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0111 0.0214
Loa Loa (eye worm) hypothetical protein 0.0266 0.0692 0.1359
Echinococcus multilocularis caspase 8 0.0029 0.0025 0.0015
Trypanosoma cruzi PAB1-binding protein , putative 0.0111 0.0255 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0045
Mycobacterium leprae cell division protein FtsZ 0.0455 0.1222 1
Plasmodium falciparum alpha tubulin 2 0.1386 0.3845 0.7544
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0068 0.0134 0.0264
Echinococcus multilocularis 6 phosphofructokinase 0.0118 0.0275 0.0266
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0044 0.0337
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.001 0.0001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0044 0.0067
Brugia malayi bZIP transcription factor family protein 0.0274 0.0713 0.1395
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0145 0.0279
Plasmodium vivax tubulin beta chain, putative 0.183 0.5093 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.005 0.0083 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Loa Loa (eye worm) alpha-tubulin 0.1386 0.3845 0.7549
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0034 0.0038 0.0028
Giardia lamblia Fructose-bisphosphate aldolase 0.0311 0.0819 0.1556
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.007 0.0139 0.1116
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0685 0.1871 0.3674
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0033 0.0044
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0044 0.0081
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.002
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0145 0.0173
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.083 0.2281 0.4476
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0072 0.0145 0.0164
Onchocerca volvulus 0.0064 0.0123 0.0559
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0044 0.0067
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0013 0.0078
Echinococcus granulosus axis inhibition protein axin 0.0045 0.007 0.0073
Echinococcus multilocularis FTZ F1 alpha 0.0072 0.0145 0.0136
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.0031 0.0062
Schistosoma mansoni transcription factor LCR-F1 0.0197 0.0496 0.0596
Echinococcus granulosus CREB binding protein 0.0207 0.0524 0.0621
Trypanosoma brucei epsilon tubulin 0.104 0.2872 0.5627
Mycobacterium tuberculosis Probable reductase 0.0238 0.0612 0.4992
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0101 0.0192
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.007 0.0139 0.1116
Brugia malayi photoreceptor-specific nuclear receptor 0.0072 0.0145 0.0279
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0047 0.0076 0.0148
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.007 0.0139 0.1116
Loa Loa (eye worm) CYP4Cod1 0.0153 0.0375 0.0736
Echinococcus multilocularis tubulin gamma 1 chain 0.1041 0.2873 0.2866
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0215 0.0548 0.1058
Schistosoma mansoni regulator of G protein signaling 0.0045 0.007 0.0082
Echinococcus granulosus cytochrome P450 2K1 0.007 0.0139 0.0157
Trypanosoma cruzi PAB1-binding protein , putative 0.0111 0.0255 0.0455
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0238 0.0612 0.4992
Echinococcus granulosus expressed protein 0.0784 0.2148 0.2581
Trypanosoma brucei metacaspase 5, putative 0.0029 0.0025 0.0023
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.007 0.0137
Loa Loa (eye worm) RGS-3 protein 0.0045 0.007 0.0137
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0037 0.0024
Brugia malayi CHE-14 protein 0.0092 0.0202 0.0391
Entamoeba histolytica hypothetical protein 0.0197 0.0496 0.0956
Trypanosoma cruzi trypanothione reductase, putative 0.0104 0.0236 0.0417
Trichomonas vaginalis tubulin, putative 0.0556 0.1507 0.2956
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.01 0.0224 0.0215
Schistosoma mansoni regulator of G protein signaling 0.0045 0.007 0.0082
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.002 0.0036
Brugia malayi A-kinase anchor protein 10, precursor 0.0045 0.007 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0408 0.0489
Loa Loa (eye worm) hypothetical protein 0.0054 0.0094 0.0184
Schistosoma mansoni tubulin subunit alpha 0.1386 0.3845 0.4632
Echinococcus multilocularis Tubulin beta 2C chain 0.183 0.5093 0.5089
Loa Loa (eye worm) hypothetical protein 0.0066 0.0128 0.0252
Echinococcus granulosus ecdysone induced protein 78C 0.0072 0.0145 0.0164
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Brugia malayi Thioredoxin reductase 0.0104 0.0236 0.0457
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.015 0.017
Echinococcus granulosus smad 0.0044 0.0068 0.0071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Echinococcus granulosus expressed conserved protein 0.0202 0.0511 0.0606
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0207 0.0524 0.063
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0147 0.0166
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0112
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0044 0.21
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0029 0.0025 0.0028
Schistosoma mansoni smad1 5 8 and 0.0044 0.0068 0.008
Echinococcus multilocularis caspase 2 0.0029 0.0025 0.0015
Echinococcus granulosus Solute carrier organic anion transporter family 0.0094 0.0206 0.0237
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0044 0.0067
Entamoeba histolytica hypothetical protein 0.0045 0.007 0.0118
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0044 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0031 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0224 0.0436
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0057 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0056 0.01 0.009
Schistosoma mansoni smad1 5 8 and 0.0044 0.0068 0.008
Schistosoma mansoni Smad4 0.0044 0.0068 0.008
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.007 0.0139 0.1116
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.01 0.0224 0.0267
Echinococcus multilocularis tubulin alpha chain 0.1386 0.3845 0.3839
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0044 0.0261
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0031 0.006
Brugia malayi Tubulin beta-1 chain 0.183 0.5093 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0044 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0134 0.0159
Brugia malayi jmjC domain containing protein 0.0066 0.0127 0.0244
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0068 0.0134 0.0238
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0293 0.0351
Brugia malayi hypothetical protein 0.0094 0.0206 0.0399
Brugia malayi beta-tubulin, identical 0.183 0.5093 1
Schistosoma mansoni retinoic acid receptor RXR 0.0072 0.0145 0.0173
Echinococcus granulosus bloom syndrome protein 0.0045 0.0069 0.0072
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.01 0.0224 0.0415
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0045 0.007 0.0082
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0049
Onchocerca volvulus 0.0031 0.0031 0.0128
Giardia lamblia Epsilon tubulin 0.0485 0.1307 0.2521
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.007 0.0133
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0092 0.0202 0.0398
Giardia lamblia Beta tubulin 0.183 0.5093 1
Schistosoma mansoni smad 0.0044 0.0068 0.008
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.007 0.0139 0.1116
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0085 0.0182 0.0218
Echinococcus granulosus alpha tubulin 0.1386 0.3845 0.4628
Echinococcus granulosus thioredoxin glutathione reductase 0.0104 0.0236 0.0273
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.007 0.0139 0.1116
Echinococcus granulosus sterol regulatory element binding protein 0.0092 0.0202 0.0233
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.004 0.003
Loa Loa (eye worm) tubulin beta chain 0.183 0.5093 1
Echinococcus multilocularis beta tubulin 0.183 0.5093 0.5089
Trypanosoma cruzi cytochrome P450, putative 0.0153 0.0375 0.069
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0044 0.0068 0.008
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Trypanosoma brucei tubulin delta chain 0.0644 0.1756 0.3431
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0068 0.0134 0.0215
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.0371 0.3014
Brugia malayi hypothetical protein 0.0111 0.0255 0.0495
Mycobacterium ulcerans 6-phosphofructokinase 0.0118 0.0275 0.2229
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0057 0.0369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Schistosoma mansoni hypothetical protein 0.0926 0.2549 0.307
Echinococcus granulosus tumor protein p63 0.1822 0.5071 0.6107
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0072 0.0145 0.0279
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0112
Leishmania major beta tubulin 0.183 0.5093 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0085 0.0183 0.0355
Mycobacterium tuberculosis Probable oxidoreductase 0.0264 0.0687 0.5605
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0033 0.006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0039
Brugia malayi regulator of G-protein signaling rgs-7 0.0045 0.007 0.0131
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0054 0.0094 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0045
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0011 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0056 0.01 0.0109
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.001 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0057 0.0106
Trichomonas vaginalis ABC transporter, putative 0.0024 0.001 0.0016
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0033 0.006
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.001 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0293 0.0284
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.01 0.0224 0.0433
Trypanosoma brucei cytochrome P450, putative 0.0153 0.0375 0.0712
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0275 0.0521
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0275 0.0536
Toxoplasma gondii endonuclease IV APN 0.0082 0.0173 0.0336
Echinococcus multilocularis 0.007 0.0139 0.013
Schistosoma mansoni survival motor neuron protein 0.0103 0.0232 0.0277
Trichomonas vaginalis ABC transporter, putative 0.0024 0.001 0.0016
Brugia malayi Cell division protein ftsZ 0.0455 0.1222 0.2395
Toxoplasma gondii alpha-tubulin I, putative 0.1386 0.3845 0.7548
Brugia malayi Cytochrome P450 family protein 0.0153 0.0375 0.0729
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0293 0.0572
Echinococcus multilocularis follistatin 0.0064 0.0123 0.0113
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0057 0.0064
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0066 0.0127 0.0142
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.0819 0.1591
Echinococcus granulosus intermediate filament protein 0.0116 0.0268 0.0312
Trypanosoma cruzi tubulin gamma chain 0.1041 0.2873 0.5619
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0045 0.007 0.0133
Schistosoma mansoni aryl hydrocarbon receptor 0.0262 0.068 0.0818
Loa Loa (eye worm) agrin synaptic family protein 0.0064 0.0123 0.0241
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0031 0.0054
Plasmodium falciparum glutathione reductase 0.0036 0.0044 0.0067
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Echinococcus granulosus tubulin gamma 1 chain 0.1041 0.2873 0.3455
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.001 0.0001
Echinococcus multilocularis hypothetical protein 0.1386 0.3845 0.3839
Schistosoma mansoni tubulin subunit alpha 0.1386 0.3845 0.4632
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0408 0.0756
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0044 0.0083
Onchocerca volvulus 0.0094 0.0206 0.0951
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0041 0.0059 0.0092
Plasmodium vivax serine/threonine kinase-1, putative 0.0068 0.0134 0.0243
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0062 0.0117 0.023
Toxoplasma gondii cytochrome p450 superfamily protein 0.007 0.0139 0.027
Echinococcus multilocularis neuropeptide s receptor 0.1014 0.2798 0.2791
Schistosoma mansoni organic anion transporter 0.0094 0.0206 0.0246
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.001 0.0001
Brugia malayi CXXC zinc finger family protein 0.0121 0.0285 0.0553
Echinococcus granulosus Tubulin beta 2C chain 0.183 0.5093 0.6134
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0173 0.0321
Brugia malayi nuclear hormone receptor 0.0072 0.0145 0.0279
Plasmodium vivax delta tubulin, putative 0.0455 0.1222 0.2385
Echinococcus multilocularis ubiquitin specific protease 41 0.0085 0.0182 0.0173
Plasmodium falciparum glutathione reductase 0.0104 0.0236 0.0444
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.007 0.0139 0.1116
Brugia malayi ABC transporter family protein 0.0024 0.001 0.0013
Schistosoma mansoni cpg binding protein 0.0121 0.0285 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0182 0.0354
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0031 0.0054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0038 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.007 0.0139 0.1116
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0101 0.0111
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0068 0.0134 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0182
Brugia malayi MH1 domain containing protein 0.0044 0.0068 0.0127
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0145 0.0136
Brugia malayi hypothetical protein 0.0031 0.0031 0.0054
Brugia malayi Protein kinase domain containing protein 0.0068 0.0134 0.0256
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.007 0.0139 0.1116
Echinococcus granulosus lipoxygenase domain containing protein 0.0212 0.0538 0.0638
Loa Loa (eye worm) tubulin beta-4 chain 0.183 0.5093 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Trichomonas vaginalis abcb9, putative 0.0024 0.001 0.0016
Echinococcus multilocularis CREB binding protein 0.0142 0.0342 0.0332
Echinococcus multilocularis Regulator of G protein signaling 20 0.0045 0.007 0.0061
Loa Loa (eye worm) DR-78 0.0031 0.0031 0.006
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0041 0.0057 0.0048
Echinococcus multilocularis tubulin beta 1 chain 0.183 0.5093 0.5089
Leishmania major beta tubulin 0.183 0.5093 1
Trichomonas vaginalis tubulin, putative 0.183 0.5093 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.0405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.002 0.0036
Schistosoma mansoni CREB-binding protein 2 0.0207 0.0524 0.063
Echinococcus multilocularis cpg binding protein 0.0128 0.0304 0.0295
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0018 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Echinococcus multilocularis tubulin alpha chain 0.1386 0.3845 0.3839
Echinococcus multilocularis lipoxygenase domain containing protein 0.0212 0.0538 0.0529
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0072 0.0145 0.0285
Plasmodium vivax ataxin-2 like protein, putative 0.0111 0.0255 0.0482
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0029 0.0025 0.0042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0293 0.2377
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0013 0.0005
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0192 0.0183
Trichomonas vaginalis guanylate cyclase, putative 0.0068 0.0134 0.026
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0064 0.0123 0.0237
Leishmania major protein kinase, putative 0.007 0.014 0.0256
Loa Loa (eye worm) CXXC zinc finger family protein 0.0121 0.0285 0.0559
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0039 0.0029
Echinococcus multilocularis caspase 3 0.008 0.0167 0.0158
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0011 0.0003
Trypanosoma cruzi epsilon tubulin, putative 0.104 0.2872 0.5617
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Echinococcus granulosus CREB binding protein 0.0034 0.0038 0.0035
Schistosoma mansoni zinc finger protein 0.0031 0.0031 0.0035
Echinococcus granulosus Tubulin alpha 1 chain 0.1386 0.3845 0.4628
Leishmania major hypothetical protein, conserved 0.0111 0.0255 0.0482
Echinococcus multilocularis smad 0.0044 0.0068 0.0059
Echinococcus multilocularis jun protein 0.0274 0.0713 0.0705
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0066 0.0127 0.0118
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0031 0.0026
Schistosoma mansoni lipoxygenase 0.0414 0.1107 0.1332
Echinococcus granulosus Tubulin beta 2C chain 0.183 0.5093 0.6134
Brugia malayi bHLH-PAS transcription factor 0.0194 0.0489 0.0954
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0039
Brugia malayi Smad1 0.0044 0.0068 0.0127
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0037 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.0145 0.0351 0.069
Echinococcus multilocularis dual specificity protein kinase clk2 0.0068 0.0134 0.0125
Trypanosoma brucei alpha tubulin 0.1386 0.3845 0.7543
Onchocerca volvulus 0.0556 0.1507 0.7047
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0794 0.2179 0.2617
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0226 0.027
Mycobacterium leprae putative cytochrome p450 0.007 0.0139 0.1116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0274 0.0713 0.0705
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0145 0.0164
Giardia lamblia Beta tubulin 0.183 0.5093 1
Echinococcus granulosus tubulin beta 4A class IVa 0.183 0.5093 0.6134
Echinococcus multilocularis Tubulin beta 2C chain 0.183 0.5093 0.5089
Echinococcus granulosus dnaJ subfamily B 0.1295 0.3587 0.4317
Loa Loa (eye worm) alpha-tubulin 0.1386 0.3845 0.7549
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.007 0.0061
Onchocerca volvulus 0.0031 0.0031 0.0128
Brugia malayi hypothetical protein 0.0031 0.0031 0.0054
Toxoplasma gondii alpha tubulin TUBA1 0.1386 0.3845 0.7548
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.001 0.0001
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.007 0.0139 0.1116
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.007 0.0139 0.1116
Leishmania major beta tubulin 0.183 0.5093 1
Treponema pallidum cell division protein FtsZ 0.0455 0.1222 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.015 0.0247
Echinococcus multilocularis transfer RNA-Lys 0.0194 0.0489 0.048
Schistosoma mansoni lamin 0.0116 0.0268 0.0321
Loa Loa (eye worm) tubulin alpha-2 chain 0.1386 0.3845 0.7549
Trichomonas vaginalis tubulin epsilon chain, putative 0.0455 0.1222 0.2397
Schistosoma mansoni tubulin subunit beta 0.183 0.5093 0.6137
Schistosoma mansoni single-minded 0.0262 0.068 0.0818
Leishmania major cytochrome p450-like protein 0.007 0.0139 0.0254
Leishmania major cytochrome p450-like protein 0.0153 0.0375 0.0717
Trypanosoma brucei PAB1-binding protein , putative 0.0111 0.0255 0.0477
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.01 0.0224 0.0415
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0085 0.0182 0.0334
Entamoeba histolytica tubulin alpha chain, putative 0.1386 0.3845 0.7544
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0192 0.0229
Trypanosoma cruzi cytochrome P450, putative 0.0153 0.0375 0.069
Onchocerca volvulus Protein ultraspiracle homolog 0.0072 0.0145 0.0664
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0085 0.0182 0.0173
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0035 0.004 0.03
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0033 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0072 0.0145 0.0285
Echinococcus granulosus tubulin epsilon chain 0.104 0.2872 0.3453
Trichomonas vaginalis tubulin beta chain, putative 0.1386 0.3845 0.7548
Onchocerca volvulus 0.0269 0.0699 0.3259
Echinococcus multilocularis Niemann Pick C1 protein 0.0307 0.0808 0.0799
Trichomonas vaginalis helicase, putative 0.0028 0.002 0.0036
Echinococcus granulosus tubulin alpha chain 0.1386 0.3845 0.4628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0226 0.027
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.007 0.0139 0.1116
Echinococcus granulosus tubulin alpha 0.101 0.2787 0.3351
Echinococcus granulosus hypothetical protein 0.0066 0.0128 0.0143
Plasmodium falciparum thioredoxin reductase 0.0036 0.0044 0.0067
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0035 0.004 0.0058
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0044 0.0337
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Echinococcus multilocularis mitogen activated protein kinase 0.0165 0.0408 0.0399
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.002 0.0036
Mycobacterium ulcerans putative regulatory protein 0.0194 0.0489 0.3982
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.007 0.0131
Echinococcus multilocularis thioredoxin glutathione reductase 0.0104 0.0236 0.0227
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0033 0.006
Schistosoma mansoni nuclear receptor 0.0031 0.0031 0.0035
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.004 0.0074
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0068 0.0134 0.026
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0072 0.0145 0.0164
Echinococcus multilocularis tubulin subunit TubB 0.1386 0.3845 0.3839
Echinococcus multilocularis tubulin alpha 0.101 0.2787 0.278
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0101 0.0226 0.027
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0137
Echinococcus granulosus follistatin 0.0064 0.0123 0.0137
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0044 0.0039
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.007 0.0139 0.1116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0819 0.1604
Brugia malayi sodium-independent organic anion transporter family protein 0.0094 0.0206 0.0399
Brugia malayi phosphofructokinase 0.0118 0.0275 0.0534
Echinococcus multilocularis microtubule associated protein 2 0.2968 0.8298 0.8296
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0031 0.0035
Onchocerca volvulus Putative organic anion transporter 0.0094 0.0206 0.0951
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.0024 0.0027
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0044 0.0051
Echinococcus granulosus mitogen activated protein kinase 0.0165 0.0408 0.0481
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0094 0.0206 0.0197
Entamoeba histolytica hypothetical protein 0.0197 0.0496 0.0956
Echinococcus granulosus tubulin alpha 3 chain 0.1386 0.3845 0.4628
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0218 0.0557 0.067
Trypanosoma brucei protein kinase, putative 0.0165 0.0408 0.0778
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0101 0.012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0123 0.0241
Echinococcus granulosus single minded 2 0.0194 0.0489 0.0578
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.007 0.0139 0.1116
Brugia malayi hypothetical protein 0.0399 0.1067 0.209
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0118 0.0275 0.2229
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0031 0.0026
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0932 0.2565 0.5037
Loa Loa (eye worm) tubulin alpha 2 0.0376 0.1001 0.1966
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Onchocerca volvulus 0.0101 0.0226 0.1042
Brugia malayi nuclear receptor RXR 0.0031 0.0031 0.0054
Echinococcus granulosus tubulin alpha chain 0.1386 0.3845 0.4628
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0104 0.0236 0.1909
Brugia malayi nuclear hormone receptor 0.0031 0.0031 0.0054
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.007 0.0073
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0147 0.0175
Loa Loa (eye worm) MH2 domain-containing protein 0.0653 0.1781 0.3497
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0063 0.0053
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0057 0.0106
Onchocerca volvulus 0.0094 0.0206 0.0951
Schistosoma mansoni RAR-like nuclear receptor 0.0072 0.0145 0.0173
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Toxoplasma gondii beta tubulin 0.183 0.5093 1
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0076 0.0089
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0047 0.0076 0.0142
Brugia malayi Cytochrome P450 family protein 0.0145 0.0351 0.0684
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.007 0.0082
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.006
Loa Loa (eye worm) phosphatidylinositol 3 0.01 0.0224 0.0439
Brugia malayi 6-phosphofructokinase 0.0118 0.0275 0.0534
Brugia malayi multidrug resistance protein 3 0.0024 0.001 0.0013
Echinococcus multilocularis tumor protein p63 0.1822 0.5071 0.5066
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.007 0.0061
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0045 0.007 0.0073
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0033 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.007 0.0133
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0072 0.0145 0.0136
Brugia malayi MAP kinase sur-1 0.0165 0.0408 0.0795
Echinococcus multilocularis RUN 0.0212 0.0538 0.0529
Leishmania major epsilon tubulin, putative 0.104 0.2872 0.563
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0013 0.0021
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0039 0.0052
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.004 0.0058
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.001 0.0001
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0085 0.0182 0.0173
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.001 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0109 0.021
Schistosoma mansoni hypothetical protein 0.0222 0.0569 0.0684
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.007 0.0139 0.1116
Echinococcus multilocularis Polycystic kidney disease protein 0.0212 0.0538 0.0529
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.007 0.0139 0.0226
Brugia malayi ecdysone receptor 0.0031 0.0031 0.0054
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0079 0.0167 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0045
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0057 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0145 0.0279
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0038 0.0028
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0068 0.0134 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.0036
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0072 0.0145 0.0136
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0044 0.0337
Onchocerca volvulus 0.078 0.2137 1
Schistosoma mansoni hypothetical protein 0.0089 0.0193 0.0231
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0057 0.0093
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.007 0.0139 0.0226
Plasmodium falciparum alpha tubulin 1 0.1386 0.3845 0.7544
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0109 0.025 0.024
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.001 0.0016
Leishmania major beta tubulin 0.183 0.5093 1
Trichomonas vaginalis tubulin gamma chain, putative 0.1041 0.2873 0.5639
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0057 0.0109
Echinococcus multilocularis lamin dm0 0.0116 0.0268 0.0259
Brugia malayi Raf kinase 0.0047 0.0075 0.014
Toxoplasma gondii target of rapamycin (TOR), putative 0.0074 0.0152 0.0294
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.015 0.027
Echinococcus multilocularis tubulin, beta 4A class IVa 0.183 0.5093 0.5089
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0118 0.0275 0.2168
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.101 0.2787 0.5469
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0035 0.004 0.003
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0044 0.0068 0.0059
Chlamydia trachomatis endonuclease IV 0.0082 0.0173 1
Loa Loa (eye worm) tubulin beta chain 0.0455 0.1222 0.24
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0044 0.0261
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0226 0.027
Brugia malayi nuclear receptor NHR-67 0.0031 0.0031 0.0054
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.0031 0.0022
Leishmania major lanosterol 14-alpha-demethylase, putative 0.007 0.0139 0.0254
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0031 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.0123 0.0241
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0068 0.0134 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0166 0.0323
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0047 0.0076 0.0124
Loa Loa (eye worm) tubulin alpha 2 0.0932 0.2565 0.5037
Loa Loa (eye worm) beta-tubulin 0.183 0.5093 1
Brugia malayi TAZ zinc finger family protein 0.0207 0.0524 0.1024
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.007 0.0073
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0031 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0076 0.0089
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0064 0.0123 0.0237
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0794 0.2179 0.2171
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0025 0.0045
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0068 0.0134 0.0245
Echinococcus granulosus beta-adrenergic receptor kinase 0.0047 0.0076 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.007 0.0133
Leishmania major protein kinase, putative 0.0068 0.0134 0.0243
Echinococcus granulosus microtubule associated protein 2 0.2968 0.8298 1
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0293 0.0351
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0165 0.0408 0.0782
Echinococcus multilocularis mothers against decapentaplegic 5 0.0044 0.0068 0.0059
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0137
Schistosoma mansoni regulator of G protein signaling 0.0046 0.0073 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0031 0.0026
Loa Loa (eye worm) glutathione reductase 0.0104 0.0236 0.0463
Trypanosoma brucei trypanothione reductase 0.0104 0.0236 0.0439
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0068 0.0134 0.0125
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.001 0.0001
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Trypanosoma brucei epsilon tubulin 0.101 0.2787 0.546
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0293 0.2377
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0271 0.0705 0.1384
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.01 0.0224 0.0393
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Echinococcus granulosus tubulin alpha 1C chain 0.1386 0.3845 0.4628
Schistosoma mansoni smad1 5 8 and 0.0044 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.034
Brugia malayi hypothetical protein 0.0041 0.0057 0.0106
Echinococcus granulosus peroxisome assembly protein 26 0.1386 0.3845 0.4628
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0238 0.0612 0.4992
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.002 0.0036
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0072 0.0145 0.0285
Loa Loa (eye worm) hypothetical protein 0.1386 0.3845 0.7549
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.007 0.0139 0.1116
Entamoeba histolytica hypothetical protein 0.0197 0.0496 0.0956
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0261 0.0678 0.0815
Schistosoma mansoni multidrug resistance protein 0.0024 0.001 0.001
Schistosoma mansoni ap endonuclease 0.0041 0.0057 0.0067
Trichomonas vaginalis guanylate cyclase, putative 0.0068 0.0134 0.026
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0069 0.006
Loa Loa (eye worm) hypothetical protein 0.0068 0.0134 0.0264
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0033 0.0044
Schistosoma mansoni smdr2 0.0024 0.001 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.002 0.0036
Echinococcus multilocularis tubulin alpha chain 0.1386 0.3845 0.3839
Schistosoma mansoni hypothetical protein 0.0285 0.0745 0.0896
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0031 0.0055
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0238 0.0612 0.4992
Echinococcus multilocularis tubulin alpha 3 chain 0.1386 0.3845 0.3839
Leishmania major beta tubulin 0.183 0.5093 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0041 0.0057 0.0058
Brugia malayi Pre-SET motif family protein 0.0101 0.0226 0.0437
Plasmodium vivax tubulin alpha chain, putative 0.1386 0.3845 0.7544
Schistosoma mansoni cellular tumor antigen P53 0.0267 0.0693 0.0833
Trypanosoma cruzi tubulin delta chain 0.0644 0.1756 0.3415
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1386 0.3845 0.7548
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0037 0.0033
Echinococcus granulosus neuropeptide s receptor 0.1014 0.2798 0.3365
Echinococcus granulosus mothers against decapentaplegic 5 0.0044 0.0068 0.0071
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0044 0.0025
Schistosoma mansoni loxhd1 0.0212 0.0538 0.0646
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.001 0.0001
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.007 0.0139 0.1116
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0031 0.0035
Brugia malayi hypothetical protein 0.0041 0.0057 0.0106
Brugia malayi SPARC precursor 0.0064 0.0123 0.0234
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.015 0.0275
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Echinococcus multilocularis Smad4 0.0044 0.0068 0.0059
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0293 0.0557
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0173 0.0334
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0057 0.0067
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0031 0.0026
Echinococcus multilocularis Tubulin beta 2C chain 0.183 0.5093 0.5089
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.007 0.0133
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.001 0.0016
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.001 0.002
Schistosoma mansoni rab6-interacting 0.0212 0.0538 0.0646
Schistosoma mansoni multidrug resistance protein 0.0024 0.001 0.001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0035 0.004 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0033 0.006
Echinococcus granulosus beta tubulin 0.183 0.5093 0.6134
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0109 0.025 0.029
Brugia malayi tubulin alpha chain - mouse 0.1386 0.3845 0.7548
Toxoplasma gondii protease inhibitor PI2 0.0064 0.0123 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.007 0.0139 0.1116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0018 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0408 0.0797
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.01 0.0224 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0094 0.0182
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0501
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.007 0.014 0.0228
Treponema pallidum NADH oxidase 0.0036 0.0044 0.0261
Schistosoma mansoni hypothetical protein 0.0103 0.0232 0.0277
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0031 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0111 0.0255 0.0482
Trypanosoma brucei metacaspase MCA3 0.0029 0.0025 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0031 0.0058
Trichomonas vaginalis ABC transporter, putative 0.0024 0.001 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0076 0.0089
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0031 0.006
Echinococcus multilocularis tubulin epsilon chain 0.104 0.2872 0.2865
Loa Loa (eye worm) steroid hormone receptor 0.0072 0.0145 0.0285
Echinococcus granulosus tubulin alpha chain 0.1386 0.3845 0.4628
Trichomonas vaginalis tubulin epsilon chain, putative 0.1386 0.3845 0.7548
Loa Loa (eye worm) intermediate filament protein 0.0116 0.0268 0.0526
Leishmania major zeta tubulin, putative 0.0771 0.2114 0.4139
Leishmania major metacaspase, putative 0.0029 0.0025 0.0029
Leishmania major alpha tubulin 0.1386 0.3845 0.7544
Schistosoma mansoni tubulin subunit beta 0.183 0.5093 0.6137
Echinococcus multilocularis dnaJ subfamily B 0.1295 0.3587 0.3581
Brugia malayi MH1 domain containing protein 0.0025 0.0012 0.0017
Schistosoma mansoni caspase-7 (C14 family) 0.0029 0.0025 0.0028
Trichomonas vaginalis tubulin alpha chain, putative 0.0556 0.1507 0.2956
Schistosoma mansoni alpha tubulin 0.1386 0.3845 0.4632
Echinococcus granulosus survival motor neuron protein 1 0.0504 0.1361 0.1631
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0932 0.2565 0.5037
Plasmodium falciparum protein serine/threonine kinase-1 0.0068 0.0134 0.0243
Schistosoma mansoni tubulin subunit delta 0.0455 0.1222 0.1471
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.007 0.0139 0.1116
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.007 0.0139 0.1116
Echinococcus granulosus beta tubulin 0.183 0.5093 0.6134
Trypanosoma brucei beta tubulin 0.183 0.5093 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Toxoplasma gondii exonuclease III APE 0.0041 0.0057 0.0109
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.007 0.014 0.0228
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.001 0.0016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0025 0.0045
Onchocerca volvulus Bile acid receptor homolog 0.0072 0.0145 0.0664
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0085 0.0182 0.0354
Brugia malayi nuclear receptor NHR-88 0.0031 0.0031 0.0054
Echinococcus multilocularis protein dispatched 1 0.0105 0.0239 0.023
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.007 0.0139 0.1116
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0072 0.0145 0.0279
Loa Loa (eye worm) pax transcription factor protein 2 0.0269 0.0699 0.1372
Loa Loa (eye worm) Smad1 0.0044 0.0068 0.0133
Brugia malayi PXA domain containing protein 0.0045 0.007 0.0131
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.015 0.0275
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0072 0.0145 0.0173
Onchocerca volvulus 0.0267 0.0693 0.3233
Schistosoma mansoni multidrug resistance protein 0.0024 0.001 0.001
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0068 0.0134 0.0215
Echinococcus granulosus raf serine:threonine protein kinase 0.0047 0.0075 0.0079
Schistosoma mansoni alpha tubulin 0.1386 0.3845 0.4632
Giardia lamblia Kinase, CMGC MAPK 0.0165 0.0408 0.0744
Loa Loa (eye worm) nuclear factor I 0.0025 0.0012 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0045
Echinococcus granulosus RUN 0.0212 0.0538 0.0638
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0037 0.0024
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0072 0.0145 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0072 0.0145 0.0279
Onchocerca volvulus 0.0072 0.0145 0.0664
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0064 0.0123 0.0234
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0101 0.0092
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0067
Trypanosoma brucei metacaspase MCA2 0.0029 0.0025 0.0023
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.01 0.0224 0.0259
Schistosoma mansoni cpg binding protein 0.0128 0.0304 0.0364
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.007 0.0139 0.1116
Leishmania major beta tubulin 0.183 0.5093 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.007 0.0139 0.1116
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0039 0.0057
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0044 0.0039
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0057 0.0093
Brugia malayi Tubulin alpha-2 chain 0.1386 0.3845 0.7548
Plasmodium vivax tubulin alpha chain, putative 0.1386 0.3845 0.7544
Trypanosoma cruzi zeta tubulin, putative 0.0771 0.2114 0.4122
Schistosoma mansoni microtubule-associated protein tau 0.2968 0.8298 1
Plasmodium vivax tubulin epsilon chain, putative 0.104 0.2872 0.563
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0165 0.0408 0.0801
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0031 0.0021
Loa Loa (eye worm) hypothetical protein 0.0072 0.0145 0.0285
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0085 0.0182 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0057 0.0109
Trypanosoma cruzi target of rapamycin kinase 3 0.0079 0.0167 0.028
Trichomonas vaginalis tubulin alpha chain, putative 0.0556 0.1507 0.2956
Brugia malayi Niemann-Pick C1 protein precursor 0.0215 0.0548 0.107
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0408 0.0797
Schistosoma mansoni tubulin subunit gamma 0.1041 0.2873 0.3461
Schistosoma mansoni caspase-3 (C14 family) 0.0109 0.025 0.0298
Trichomonas vaginalis tubulin beta chain, putative 0.1386 0.3845 0.7548
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0166 0.0323
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0085 0.0182 0.0339
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0061 0.0101
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0044 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0134 0.026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0085 0.0182 0.0354
Trypanosoma brucei beta tubulin 0.101 0.2787 0.546
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0033 0.0044
Brugia malayi hypothetical protein 0.0045 0.007 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0152 0.0294
Trypanosoma cruzi beta tubulin, putative 0.183 0.5093 1
Echinococcus multilocularis geminin 0.0926 0.2549 0.2542
Entamoeba histolytica tubulin gamma chain 0.1041 0.2873 0.5632
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0064 0.0123 0.0241

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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