Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.03 ug ml-1 | Antibacterial activity against Streptococcus pyogenes | ChEMBL. | 2115587 |
MIC (functional) | = 0.03 ug ml-1 | Antibacterial activity against E. coli TEM | ChEMBL. | 2115587 |
MIC (functional) | = 0.03 ug ml-1 | Antibacterial activity against E. coli TEM | ChEMBL. | 2115587 |
MIC (functional) | = 0.06 ug ml-1 | Antibacterial activity against Streptococcus pneumoniae | ChEMBL. | 2115587 |
MIC (functional) | = 0.06 ug ml-1 | Antibacterial activity against E. coli EC14 | ChEMBL. | 2115587 |
MIC (functional) | = 0.06 ug ml-1 | Antibacterial activity against Klebsiella pneumoniae X26 | ChEMBL. | 2115587 |
MIC (functional) | = 0.06 ug ml-1 | Antibacterial activity against E. coli EC14 | ChEMBL. | 2115587 |
MIC (functional) | = 0.25 ug ml-1 | Antibacterial activity against Enterobacter cloacae EB5 | ChEMBL. | 2115587 |
MIC (functional) | = 0.25 ug ml-1 | Antibacterial activity against S. marcens SE3 | ChEMBL. | 2115587 |
MIC (functional) | = 2 ug ml-1 | Antibacterial activity against penicillin G susceptable Staphylococcus aureus | ChEMBL. | 2115587 |
MIC (functional) | = 4 ug ml-1 | Antibacterial activity against penicillin G resistance Staphylococcus aureus | ChEMBL. | 2115587 |
MIC (functional) | = 4 ug ml-1 | Antibacterial activity against Klebsiella pneumoniae 1082E | ChEMBL. | 2115587 |
MIC (functional) | = 4 ug ml-1 | Antibacterial activity against Enterobacter cloacae 265A | ChEMBL. | 2115587 |
MIC (functional) | = 16 ug ml-1 | Antibacterial activity against Pseudomonas aeruginosa X528 | ChEMBL. | 2115587 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Enterococcus faecium | ChEMBL. | 2115587 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Pseudomonas aeruginosa PS18 | ChEMBL. | 2115587 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.