Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.4959 | 0.4959 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0 | 0.5 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0523 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2556 | 0.3078 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0459 | 0.0552 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0523 | 0.5 |
Brugia malayi | RNA binding protein | 0.0063 | 0.2556 | 0.2556 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0523 | 0.0523 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2556 | 0.3078 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0523 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0523 | 0.063 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.2556 | 0.2556 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0523 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0523 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0523 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0459 | 0.0459 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.2556 | 0.2556 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.2556 | 0.2556 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1557 | 0.1557 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0523 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0523 | 0.5 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0523 | 0.0523 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.2556 | 0.2556 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0523 | 0.0523 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.8304 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0523 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2556 | 0.3078 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0523 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2556 | 0.3078 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0459 | 0.0459 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2556 | 0.3078 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0523 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.4959 | 0.4959 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0523 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0459 | 0.0552 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0459 | 0.0459 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0523 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0523 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Onchocerca volvulus | 0.0093 | 0.4865 | 1 | |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.8304 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0523 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0161 | 1 | 1 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.2556 | 0.2556 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0854 | 0.0854 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.3492 | 0.4205 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0854 | 0.0854 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0523 | 0.0523 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.4959 | 0.4959 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.2556 | 0.2556 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0459 | 0.0459 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.2321 | 0.2321 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0523 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.2556 | 0.2556 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.