Detailed information for compound 1080916

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 824.959 | Formula: C42H60N6O11
  • H donors: 8 H acceptors: 11 LogP: 4.22 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCCCC(=O)N([C@@H](C(=O)N[C@@H](C(=O)NCC(=O)N([C@@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](Cc2cc(c3cc1ccc3O)c(O)cc2)C(=O)O)C)C)CO)C
  • InChi: 1S/C42H60N6O11/c1-6-7-8-9-10-11-12-13-14-15-35(52)47(4)32(24-49)40(56)44-25(2)38(54)43-23-36(53)48(5)37-28-17-19-34(51)30(22-28)29-20-27(16-18-33(29)50)21-31(42(58)59)46-39(55)26(3)45-41(37)57/h16-20,22,25-26,31-32,37,49-51H,6-15,21,23-24H2,1-5H3,(H,43,54)(H,44,56)(H,45,57)(H,46,55)(H,58,59)/t25-,26+,31+,32-,37+/m1/s1
  • InChiKey: QAHUKEDKLUUKAN-JBBOGOJTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0047 0.0025 0.0028
Echinococcus granulosus endoplasmin 0.0048 0.0027 0.0027
Trypanosoma cruzi heat shock protein, putative 0.0034 0.0006 0.0008
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0011 0.0011
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0091 0.009 0.0131
Onchocerca volvulus 0.0042 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0032 0.0002 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.0418 0.0576 0.0576
Mycobacterium ulcerans lipase LipD 0.0411 0.0567 0.0556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0017 0.0059
Trypanosoma cruzi carnitine O-palmitoyltransferase II, putative 0.0042 0.0018 0.0025
Brugia malayi Augmenter of liver regeneration 0.0041 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0063 0.0217
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0006 0.0008
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0011 0.0038
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.005 0.0029 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0999 0.1442 0.1442
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.005 0.0029 0.0017
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0173 0.0212 0.0211
Echinococcus granulosus dna polymerase eta 0.0038 0.0011 0.0011
Echinococcus multilocularis endoplasmin 0.0048 0.0027 0.0027
Echinococcus granulosus heat shock protein 90 0.0044 0.002 0.002
Toxoplasma gondii propionate-CoA ligase 0.005 0.0029 0.0034
Echinococcus granulosus snurportin 1 0.0999 0.1442 0.1442
Wolbachia endosymbiont of Brugia malayi Signal peptidase I 0.0239 0.0311 0.2686
Schistosoma mansoni tar DNA-binding protein 0.0653 0.0927 0.0927
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0041 0.0015 0.0022
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0092 0.0091 0.1561
Echinococcus granulosus histone acetyltransferase KAT2B 0.0163 0.0198 0.0198
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0352 0.0479 0.0479
Brugia malayi jmjC domain containing protein 0.0079 0.0072 0.0071
Trypanosoma brucei glucosidase, putative 0.0149 0.0176 0.0258
Schistosoma mansoni hypothetical protein 0.0403 0.0554 0.0554
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.6747 1 1
Brugia malayi PHD-finger family protein 0.006 0.0044 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0055 0.0036 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.005 0.0029 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0149 0.0176 0.0605
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.0231 0.0298 0.0437
Schistosoma mansoni chromobox protein 0.0139 0.0162 0.0162
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.017 0.0207 0.0196
Brugia malayi MH1 domain containing protein 0.0058 0.0041 0.004
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.008 0.0073 0.0073
Trichomonas vaginalis alpha-glucosidase, putative 0.0055 0.0037 0.0126
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0011 0.0011
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0092 0.0091 0.1561
Loa Loa (eye worm) hypothetical protein 0.0411 0.0567 0.0566
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0006 0.0006
Trichomonas vaginalis endoplasmin, putative 0.0038 0.001 0.0034
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0411 0.0567 0.0561
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0041 0.0041
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0042 0.3815
Trypanosoma cruzi ISWI complex protein 0.0031 0.0001 0.0001
Brugia malayi chromobox protein homolog 3 0.0078 0.0071 0.007
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.005 0.0029 0.0002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0043 0.0043
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0022 0.0024
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.005 0.0029 0.0017
Brugia malayi Fli-1 protein 0.024 0.0312 0.0312
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0759 0.1084 0.1061
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.0042 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0127 0.0143 0.0143
Brugia malayi Ets-domain containing protein 0.0079 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0165 0.0201 0.02
Toxoplasma gondii heat shock protein HSP90 0.0052 0.0031 0.0038
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0029 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0217 0.0277 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Echinococcus multilocularis choline O acetyltransferase 0.0042 0.0018 0.0018
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0011 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0274 0.0362 0.0362
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0068 0.0092
Mycobacterium ulcerans hypothetical protein 0.0341 0.0462 0.0451
Echinococcus multilocularis sterol regulatory element binding protein 0.0093 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0042 0.0018 0.0017
Plasmodium vivax ataxin-2 like protein, putative 0.0184 0.0228 0.0327
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Loa Loa (eye worm) heat shock protein 75 0.0034 0.0006 0.0005
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Entamoeba histolytica heat shock protein 90, putative 0.0052 0.0031 0.0471
Mycobacterium tuberculosis Probable signal peptidase I LepB (SPASE I) (leader peptidase I). 0.0239 0.0311 0.0305
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0092 0.0091 0.0134
Echinococcus granulosus TGF beta signal transducer SmadC 0.0058 0.0041 0.0041
Mycobacterium ulcerans signal peptidase I LepB 0.0239 0.0311 0.03
Echinococcus granulosus zinc finger protein 0.0049 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0055 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.017 0.0207 0.0207
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0231 0.0298 0.0437
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.005 0.0029 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.001
Brugia malayi Choline O-acetyltransferase 0.0042 0.0018 0.0017
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0411 0.0567 0.0566
Schistosoma mansoni cpg binding protein 0.0086 0.0083 0.0082
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0011 0.0016
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0042 0.0042
Echinococcus multilocularis heat shock protein 0.0052 0.0031 0.0031
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.005 0.0029 0.0017
Leishmania major acetyl-CoA synthetase, putative 0.005 0.0029 0.0042
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0068 0.0092
Brugia malayi PHD-finger family protein 0.0058 0.0041 0.004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0055 0.0036 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0184 0.0228 0.0334
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0251 0.0328 0.0474
Schistosoma mansoni cpg binding protein 0.0095 0.0096 0.0095
Mycobacterium ulcerans acetyl-CoA synthetase 0.005 0.0029 0.0017
Brugia malayi MAP kinase sur-1 0.0059 0.0042 0.0041
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0004 0.0013
Echinococcus granulosus muscleblind protein 0.0165 0.0201 0.0201
Onchocerca volvulus 0.109 0.1578 0.5431
Schistosoma mansoni survival motor neuron protein 0.0056 0.0038 0.0038
Echinococcus granulosus dihydrofolate reductase 0.6747 1 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0055 0.0036 0.0035
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0761 0.1087 0.1087
Giardia lamblia PHD finger protein 15 0.0058 0.0041 0.3664
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.017 0.0207 0.0201
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.001
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0043 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.0055 0.0037 0.0126
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0042 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0036 0.0124
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0043 0.0037
Brugia malayi Pre-SET motif family protein 0.0251 0.0328 0.0328
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0044 0.002 0.002
Schistosoma mansoni nuclear hormone receptor 0.0055 0.0036 0.0035
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0406 0.0559 0.0559
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0042 0.0061
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.009 0.0088 0.0088
Mycobacterium leprae Conserved hypothetical protein 0.2238 0.3286 0.3268
Echinococcus granulosus histone lysine methyltransferase setb 0.0286 0.038 0.038
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0029 0.0023
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.005 0.0029 0.0034
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0029 0.0029
Plasmodium falciparum acetyl-CoA synthetase, putative 0.005 0.0029 0.0034
Leishmania major heat shock protein, putative 0.0034 0.0006 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0139 0.0162 0.0557
Echinococcus granulosus lamin dm0 0.0081 0.0075 0.0075
Toxoplasma gondii hypothetical protein 0.0104 0.011 0.0153
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0036 0.0036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0055 0.0036 0.0036
Leishmania major importin beta-1 subunit, putative 0.0076 0.0068 0.0099
Mycobacterium tuberculosis Probable hydrolase 0.0411 0.0567 0.0561
Schistosoma mansoni hypothetical protein 0.0352 0.0479 0.0478
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0091 0.009 0.0131
Trypanosoma cruzi importin beta-1 subunit, putative 0.0076 0.0068 0.0099
Echinococcus granulosus ecdysone induced protein 78C 0.0055 0.0036 0.0036
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0092 0.0091 0.0091
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0042 0.0018 0.0025
Echinococcus multilocularis thymidylate synthase 0.109 0.1578 0.1578
Mycobacterium ulcerans recombinase A 0.0212 0.027 0.0259
Mycobacterium ulcerans hypothetical protein 0.0411 0.0567 0.0556
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.012 0.0133 0.0127
Echinococcus multilocularis peregrin 0.0067 0.0054 0.0054
Schistosoma mansoni dihydrofolate reductase 0.6747 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0008 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Echinococcus granulosus GTP binding nuclear protein Ran 0.0047 0.0025 0.0025
Trypanosoma brucei heat shock protein 84, putative 0.0034 0.0006 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0055 0.0036 0.0036
Echinococcus multilocularis geminin 0.0876 0.1259 0.1259
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Loa Loa (eye worm) heterochromatin protein 1 0.0139 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0041 0.0051
Onchocerca volvulus 0.0042 0.0018 0.0041
Brugia malayi acetyltransferase, GNAT family protein 0.0173 0.0212 0.0211
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0389 0.0533 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Trichomonas vaginalis ran, putative 0.0047 0.0025 0.0084
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0068 0.0068
Brugia malayi CHE-14 protein 0.0093 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Schistosoma mansoni hypothetical protein 0.0042 0.0017 0.0017
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0041 0.0015 0.0014
Onchocerca volvulus 0.005 0.0029 0.008
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0063 0.0093
Schistosoma mansoni hypothetical protein 0.0761 0.1087 0.1087
Schistosoma mansoni ap endonuclease 0.0059 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0043 0.0148
Trypanosoma brucei carnitine O-acetyltransferase, putative 0.0042 0.0018 0.0025
Brugia malayi Importin beta-1 subunit 0.0094 0.0094 0.0093
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0017 0.0059
Brugia malayi isocitrate dehydrogenase 0.0034 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0352 0.0479 0.0478
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0031 0.0046
Echinococcus granulosus smad 0.0058 0.0041 0.0041
Plasmodium vivax acetyl-CoA synthetase, putative 0.005 0.0029 0.0034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.012 0.0133 0.0127
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0217 0.0277 0.4954
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0047 0.0025 0.0025
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0032 0.0002 0.0001
Onchocerca volvulus Huntingtin homolog 0.0252 0.033 0.1121
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0047 0.0025 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0295 0.0394 0.0394
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0075 0.0075
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0092 0.0091 0.0134
Schistosoma mansoni gabp alpha 0.0079 0.0072 0.0072
Schistosoma mansoni Smad4 0.0058 0.0041 0.004
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0068
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0011 0.0006
Trypanosoma brucei protein kinase, putative 0.0059 0.0042 0.0061
Trypanosoma brucei glycosyl hydrolase-like protein 0.0055 0.0037 0.0054
Leishmania major DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0127 0.0143 0.0143
Schistosoma mansoni ap endonuclease 0.0059 0.0043 0.0043
Plasmodium falciparum heat shock protein 90, putative 0.0196 0.0246 0.0353
Trypanosoma brucei heat shock protein 90, putative 0.0052 0.0031 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Loa Loa (eye worm) hypothetical protein 0.0081 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0411 0.0567 0.0566
Mycobacterium tuberculosis Conserved protein 0.0411 0.0567 0.0561
Schistosoma mansoni endoplasmin 0.0052 0.0031 0.0031
Trypanosoma brucei unspecified product 0.0038 0.0011 0.0016
Echinococcus multilocularis GPCR, family 2 0.0352 0.0479 0.0479
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0011 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0036 0.0124
Brugia malayi heat shock protein 90 0.0052 0.0031 0.0031
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.017 0.0207 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0046 0.0158
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0063 0.0093
Onchocerca volvulus 0.0387 0.0531 0.1816
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.005 0.0029 0.0023
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0082 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0039 0.0013 0.0012
Plasmodium vivax heat shock protein, putative 0.0196 0.0246 0.0354
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0411 0.0567 0.0566
Onchocerca volvulus 0.017 0.0207 0.0696
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0006 0.0006
Echinococcus multilocularis chromobox protein 1 0.0139 0.0162 0.0162
Echinococcus multilocularis neutral alpha glucosidase AB 0.0149 0.0176 0.0176
Echinococcus granulosus tar DNA binding protein 0.0653 0.0927 0.0927
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.109 0.1578 0.1578
Trypanosoma cruzi ISWI complex protein 0.0031 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0035 0.0035
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0041 0.0015 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0055 0.0036 0.0035
Echinococcus granulosus choline O acetyltransferase 0.0042 0.0018 0.0018
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0352 0.0479 0.0479
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0533 0.0533
Echinococcus granulosus Niemann Pick C1 protein 0.031 0.0416 0.0416
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.0366 0.0366
Mycobacterium ulcerans beta-lactamase 0.0411 0.0567 0.0556
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.005 0.0029 0.0029
Onchocerca volvulus 0.015 0.0178 0.0594
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0048 0.0027 0.0021
Onchocerca volvulus Alhambra homolog 0.0058 0.0041 0.0121
Brugia malayi Pre-SET motif family protein 0.1739 0.2544 0.2543
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0018 0.0025
Trypanosoma cruzi heat shock protein 90, putative 0.0044 0.002 0.0029
Echinococcus multilocularis heat shock protein 90 0.0044 0.002 0.002
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0029 0.0023
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0006 0.0005
Onchocerca volvulus 0.0411 0.0567 0.1938
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.017 0.0207 0.0181
Echinococcus granulosus neutral alpha glucosidase AB 0.0149 0.0176 0.0176
Schistosoma mansoni endoplasmin 0.0052 0.0031 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0411 0.0567 0.0832
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0519 0.0727 0.1067
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0037 0.0126
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Brugia malayi beta-lactamase family protein 0.0411 0.0567 0.0566
Echinococcus granulosus beta LACTamase domain containing family member 0.0411 0.0567 0.0567
Loa Loa (eye worm) transcription factor SMAD2 0.0849 0.1219 0.1218
Brugia malayi Steroid receptor seven-up type 2 0.0055 0.0036 0.0035
Loa Loa (eye worm) CHromoDomain protein family member 0.0032 0.0002 0.0001
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0041 0.0015 0.0014
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0051 0.003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0099 0.0102 0.0102
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0127 0.0143 0.0138
Brugia malayi Glycosyl hydrolases family 31 protein 0.067 0.0952 0.0951
Toxoplasma gondii Erv1 / Alr family protein 0.0041 0.0015 0.0014
Plasmodium falciparum heat shock protein 90 0.0052 0.0031 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0019 0.0028
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0083 0.0082
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0055 0.0037 0.0108
Schistosoma mansoni lamin 0.0081 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.005 0.0029 0.0028
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0041 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0037 0.0126
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0036 0.0036
Echinococcus granulosus peregrin 0.0067 0.0054 0.0054
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0029 0.0002
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.005 0.0029 0.0042
Loa Loa (eye worm) hypothetical protein 0.0093 0.0093 0.0093
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0042 0.0042
Schistosoma mansoni importin beta-1 0.0094 0.0094 0.0093
Onchocerca volvulus 0.005 0.0029 0.008
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0029 0.0023
Echinococcus multilocularis tumor protein p63 0.3462 0.5108 0.5108
Trichomonas vaginalis maltase-glucoamylase, putative 0.0055 0.0037 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0071 0.0244
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0042 0.0018 0.0025
Schistosoma mansoni alpha-glucosidase 0.0577 0.0813 0.0813
Brugia malayi RNA, U transporter 1 0.0266 0.0351 0.035
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0006 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.009 0.0131
Loa Loa (eye worm) nuclear factor I 0.0032 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0094 0.0094 0.0093
Trypanosoma cruzi DNA repair protein, putative 0.0065 0.0052 0.0075
Echinococcus multilocularis lamin dm0 0.0081 0.0075 0.0075
Plasmodium vivax acyl-CoA synthetase, putative 0.0127 0.0143 0.0202
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.015 0.0213
Schistosoma mansoni steroid hormone receptor ad4bp 0.0055 0.0036 0.0035
Leishmania major dihydrofolate reductase-thymidylate synthase 0.4602 0.6807 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0036 0.0035
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.005 0.0029 0.042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.012 0.0133 0.0127
Loa Loa (eye worm) hypothetical protein 0.0679 0.0966 0.0965
Schistosoma mansoni hypothetical protein 0.0876 0.1259 0.1259
Loa Loa (eye worm) Smad1 0.0058 0.0041 0.004
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0176 0.0258
Echinococcus granulosus fetal alzheimer antigen falz 0.0051 0.003 0.003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0352 0.0479 0.0478
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0047 0.0025 0.0028
Brugia malayi MH2 domain containing protein 0.0058 0.0041 0.004
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0047 0.0025 0.0024
Echinococcus granulosus thymidylate synthase 0.109 0.1578 0.1578
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.015 0.0145
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0131 0.015 0.015
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0096 0.0098 0.0097
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0055 0.0036 0.0036
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0011 0.0011
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0055 0.0037 0.0037
Echinococcus multilocularis jumonji domain containing protein 0.008 0.0074 0.0074
Leishmania major DNA polymerase eta, putative 0.0038 0.0011 0.0016
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0064 0.0064
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0646 0.0917 0.1347
Chlamydia trachomatis replicative DNA helicase 0.0759 0.1084 0.1023
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0019 0.0019
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Echinococcus multilocularis lamin 0.0081 0.0075 0.0075
Brugia malayi hypothetical protein 0.0119 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0217 0.0277 0.0277
Onchocerca volvulus 0.0411 0.0567 0.1938
Brugia malayi beta-lactamase family protein 0.0411 0.0567 0.0566
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0286 0.038 0.038
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0064 0.0064
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0036 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Schistosoma mansoni bromodomain containing protein 0.0138 0.016 0.016
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0011 0.0011
Echinococcus granulosus microtubule associated protein 2 0.6297 0.933 0.933
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0043 0.0062
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.067 0.0952 0.0951
Echinococcus multilocularis Niemann Pick C1 protein 0.0217 0.0277 0.0277
Echinococcus multilocularis mothers against decapentaplegic 5 0.0058 0.0041 0.0041
Trypanosoma brucei carnitine O-palmitoyltransferase, putative 0.0042 0.0018 0.0025
Trypanosoma cruzi carnitine O-acetyltransferase, putative 0.0042 0.0018 0.0025
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0011 0.0104
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0058 0.0041 0.004
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.4602 0.6807 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0017 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0042 0.0143
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0019 0.0019
Leishmania major mitochondrial DNA polymerase beta 0.0646 0.0917 0.1347
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0055 0.0036 0.0035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0006 0.0006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0055 0.0037 0.0126
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0149 0.0176 0.0605
Echinococcus multilocularis dna polymerase eta 0.0038 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0068 0.0055 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.015 0.0139
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0042 0.0042
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0042 0.0018 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0192 0.024 0.0239
Brugia malayi MH1 domain containing protein 0.0032 0.0002 0.0002
Schistosoma mansoni ran 0.0047 0.0025 0.0024
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0679 0.0966 0.0965
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0017 0.0059
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0011 0.0011
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0047 0.0025 0.1665
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0043 0.0062
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0286 0.038 0.038
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0646 0.0917 0.1347
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.0031 0.0046
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0092 0.0091 0.0134
Schistosoma mansoni ets-related 0.024 0.0312 0.0312
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0076 0.0068 0.0231
Mycobacterium tuberculosis Hypothetical protein 0.0519 0.0727 0.0721
Mycobacterium ulcerans fatty-acid-CoA ligase 0.017 0.0207 0.0196
Loa Loa (eye worm) hypothetical protein 0.0077 0.0068 0.0068
Schistosoma mansoni choline o-acyltransferase 0.0042 0.0018 0.0017
Giardia lamblia GTOR 0.0092 0.0091 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.012 0.0133 0.0127
Schistosoma mansoni cellular tumor antigen P53 0.0507 0.0709 0.0709
Mycobacterium ulcerans heat shock protein 90 0.0048 0.0027 0.0015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0055 0.0036 0.0035
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.005 0.0029 0.0042
Onchocerca volvulus 0.0086 0.0083 0.0266
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0093 0.0093 0.0093
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0041 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0411 0.0567 0.1953
Leishmania major hypothetical protein, conserved 0.0253 0.0331 0.0486
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.005 0.0029 0.0023
Echinococcus multilocularis snurportin 1 0.0999 0.1442 0.1442
Echinococcus multilocularis thyroid hormone receptor alpha 0.0187 0.0232 0.0232
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0042 0.0041
Brugia malayi Choline O-acetyltransferase 0.0042 0.0018 0.0017
Plasmodium vivax SET domain protein, putative 0.0251 0.0328 0.0474
Trichomonas vaginalis heat shock protein, putative 0.0044 0.002 0.0069
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0055 0.0036 0.0035
Trypanosoma brucei ISWI complex protein 0.0031 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.005 0.0029 0.0028
Trichomonas vaginalis set domain proteins, putative 0.1979 0.2901 1
Toxoplasma gondii Erv1 / Alr family protein 0.0041 0.0015 0.0014
Brugia malayi TAR-binding protein 0.0653 0.0927 0.0927
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0403 0.0554 0.0554
Plasmodium falciparum endoplasmin, putative 0.0038 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0144 0.017 0.0169
Loa Loa (eye worm) RNA binding protein 0.0653 0.0927 0.0927
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0533 0.0533
Onchocerca volvulus 0.0411 0.0567 0.1938
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0036 0.0035
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0008 0.0008
Loa Loa (eye worm) dihydrofolate reductase 0.6747 1 1
Schistosoma mansoni hypothetical protein 0.009 0.0088 0.0088
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0029 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0084 0.008 0.0273
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0092 0.0091 0.0134
Trypanosoma cruzi choline/carnitine O-acetyltransferase, putative 0.0042 0.0018 0.0025
Schistosoma mansoni alpha-glucosidase 0.0577 0.0813 0.0813
Trypanosoma cruzi hypothetical protein, conserved 0.0253 0.0331 0.0486
Loa Loa (eye worm) AMP-binding enzyme family protein 0.005 0.0029 0.0028
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0041 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0418 0.0576 0.0576
Loa Loa (eye worm) hypothetical protein 0.0078 0.0071 0.007
Echinococcus granulosus Niemann Pick C1 protein 0.0217 0.0277 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0055 0.0036 0.0035
Brugia malayi acetyl-Coenzyme A synthetase 2 0.005 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0087 0.0085 0.0084
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0072 0.0071
Brugia malayi AMP-binding enzyme family protein 0.005 0.0029 0.0028
Brugia malayi Calcitonin receptor-like protein seb-1 0.1113 0.1611 0.1611
Echinococcus granulosus heat shock protein 0.0052 0.0031 0.0031
Mycobacterium leprae conserved hypothetical protein 0.0411 0.0567 0.0541
Trichomonas vaginalis alpha-glucosidase, putative 0.0149 0.0176 0.0605
Treponema pallidum recombinase A 0.0212 0.027 0.23
Entamoeba histolytica acyl-coA synthetase, putative 0.017 0.0207 0.3673
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0341 0.0462 0.0456
Schistosoma mansoni hypothetical protein 0.0352 0.0479 0.0478
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0411 0.0567 0.0566
Schistosoma mansoni cpg binding protein 0.0095 0.0096 0.0095
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0189 0.0237 0.0237
Trypanosoma cruzi PAB1-binding protein , putative 0.0184 0.0228 0.0334
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.024 0.0312 0.0312
Giardia lamblia Heat shock protein HSP 90-alpha 0.0044 0.002 0.1124
Loa Loa (eye worm) hypothetical protein 0.0127 0.0143 0.0143
Brugia malayi MH2 domain containing protein 0.0058 0.0041 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0411 0.0567 0.0832
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0653 0.0927 0.0927
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0042 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0184 0.0228 0.0228
Loa Loa (eye worm) TAR-binding protein 0.0653 0.0927 0.0927
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0017 0.0059
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0048 0.0027 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0043 0.0062
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.6747 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0149 0.0176 0.0605
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0041 0.0015 0.0022
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0078 0.0071 0.0225
Giardia lamblia Heat shock protein HSP 90-alpha 0.0052 0.0031 0.2515
Trichomonas vaginalis conserved hypothetical protein 0.0519 0.0727 0.2505
Echinococcus multilocularis importin subunit beta 1 0.0094 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0058 0.0041 0.004
Echinococcus granulosus importin subunit beta 1 0.0094 0.0094 0.0094
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Trypanosoma cruzi DNA repair protein, putative 0.0065 0.0052 0.0075
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0006 0.0008
Echinococcus multilocularis heat shock protein 90 0.0052 0.0031 0.0031
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0055 0.0037 0.0126
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2627 0.3866 0.3862
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0394
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0006 0.0006
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Brugia malayi Glycosyl hydrolases family 31 protein 0.0055 0.0037 0.0037
Brugia malayi intermediate filament protein 0.0081 0.0075 0.0075
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0055 0.0036 0.0036
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0008 0.0008
Echinococcus granulosus heat shock protein 90 0.0052 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0055 0.0036 0.0035
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Schistosoma mansoni hypothetical protein 0.0058 0.0041 0.004
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.0151 0.0151
Echinococcus multilocularis expressed conserved protein 0.0204 0.0258 0.0258
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0149 0.0176 0.3103
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.005 0.0029 0.0042
Brugia malayi nuclear hormone receptor 0.0055 0.0036 0.0035
Loa Loa (eye worm) endoplasmin 0.0052 0.0031 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0132 0.0132
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0043 0.0679
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0092 0.0091 0.0091
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0759 0.1084 1
Loa Loa (eye worm) hepatopoietin HPO2 0.0041 0.0015 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0072 0.0071
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.005 0.0029 0.0002
Loa Loa (eye worm) hypothetical protein 0.0061 0.0046 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0055 0.0037 0.0126
Trichomonas vaginalis heat shock protein, putative 0.0048 0.0027 0.0091
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0042 0.0018 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0091 0.0313
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0055 0.0036 0.0035
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.0042 0.0018 0.0017
Schistosoma mansoni zinc finger protein 0.0031 0.0001 0.0001
Toxoplasma gondii LsmAD domain-containing protein 0.0184 0.0228 0.0327
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0032 0.0002 0.0002
Chlamydia trachomatis signal peptidase I 0.0239 0.0311 0.0244
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0212 0.027 0.0244
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0131 0.015 0.015
Echinococcus granulosus dna polymerase kappa 0.0038 0.0011 0.0011
Onchocerca volvulus 0.0507 0.0709 0.2429
Schistosoma mansoni DNA polymerase eta 0.0038 0.0011 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0411 0.0567 0.0561
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.005 0.0029 0.0023
Schistosoma mansoni heat shock protein 0.0052 0.0031 0.0031
Loa Loa (eye worm) heat shock protein 90 0.0052 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0063 0.0217
Trichomonas vaginalis maltase-glucoamylase, putative 0.0149 0.0176 0.0605
Brugia malayi hypothetical protein 0.0403 0.0554 0.0554
Echinococcus multilocularis chromobox protein 1 0.0139 0.0162 0.0162
Brugia malayi hypothetical protein 0.0519 0.0727 0.0726
Loa Loa (eye worm) hypothetical protein 0.0252 0.033 0.033
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0189 0.0237 0.0237
Schistosoma mansoni transcription factor LCR-F1 0.0403 0.0554 0.0554
Toxoplasma gondii histone lysine methyltransferase SET1 0.0181 0.0224 0.0321
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0068
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2571 0.3782 0.3782
Echinococcus multilocularis protein dispatched 1 0.0106 0.0113 0.0113
Schistosoma mansoni zinc finger protein 0.0049 0.0028 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0149 0.0176 0.0605
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0055 0.0036 0.0036
Loa Loa (eye worm) thymidylate synthase 0.109 0.1578 0.1578
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0055 0.0036 0.0036
Echinococcus multilocularis microtubule associated protein 2 0.6297 0.933 0.933
Loa Loa (eye worm) hypothetical protein 0.017 0.0207 0.0207
Schistosoma mansoni lamin 0.0081 0.0075 0.0075
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0006 0.0006
Toxoplasma gondii heat shock protein 90, putative 0.0052 0.0031 0.0038
Onchocerca volvulus 0.005 0.0029 0.008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0411 0.0567 0.0567
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0036 0.0124
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0042 0.0061
Loa Loa (eye worm) oxidoreductase 0.005 0.0029 0.0028
Brugia malayi MH1 domain containing protein 0.0058 0.0041 0.004
Brugia malayi Smad1 0.0058 0.0041 0.004
Onchocerca volvulus 0.0055 0.0036 0.0104
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0006 0.0008
Entamoeba histolytica hypothetical protein 0.0403 0.0554 1
Echinococcus granulosus Smad4 0.0058 0.0041 0.0041
Brugia malayi Glycosyl hydrolases family 31 protein 0.0149 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.005 0.0029 0.0028
Trichomonas vaginalis penicillin-binding protein, putative 0.0411 0.0567 0.1953
Brugia malayi AMP-binding enzyme family protein 0.005 0.0029 0.0028
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0018 0.0025
Brugia malayi beta-lactamase 0.0411 0.0567 0.0566
Schistosoma mansoni hypothetical protein 0.0876 0.1259 0.1259
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.005 0.0029 0.0029
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0011 0.0016
Brugia malayi Heterochromatin protein 1 0.0139 0.0162 0.0162
Schistosoma mansoni heat shock protein 0.0034 0.0006 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0055 0.0036 0.0036
Echinococcus granulosus dnaJ subfamily B 0.0418 0.0576 0.0576
Schistosoma mansoni jumonji domain containing protein 0.015 0.0179 0.0178
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0041 0.0041
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0411 0.0567 0.0566
Trichomonas vaginalis heat shock protein, putative 0.0048 0.0027 0.0091
Schistosoma mansoni RAR-like nuclear receptor 0.0055 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0114 0.0124 0.0124
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0231 0.0298 0.0437
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.015 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0176 0.0258
Trichomonas vaginalis esterase, putative 0.0411 0.0567 0.1953
Schistosoma mansoni ran 0.0047 0.0025 0.0024
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0047 0.0025 0.0036
Schistosoma mansoni Replicative DNA helicase 0.0759 0.1084 0.1084
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0013 0.0013
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0063 0.0093
Loa Loa (eye worm) hypothetical protein 0.0286 0.038 0.038
Entamoeba histolytica hypothetical protein 0.0403 0.0554 1
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.017 0.0207 0.0196
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0035 0.0044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0043 0.0153
Leishmania major 4-coumarate:coa ligase-like protein 0.017 0.0207 0.0304
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0042 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0761 0.1087 0.1087
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0043 0.0055
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.015 0.015
Mycobacterium tuberculosis Conserved protein 0.0411 0.0567 0.0561
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0011 0.0016
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1113 0.1611 0.1611
Loa Loa (eye worm) hypothetical protein 0.005 0.0029 0.0028
Echinococcus granulosus mothers against decapentaplegic 5 0.0058 0.0041 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0018 0.0025
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0306 0.041 0.0602
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0036 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0306 0.041 0.0602
Brugia malayi hypothetical protein 0.0184 0.0228 0.0228
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0389 0.0533 0.0533
Echinococcus granulosus jumonji domain containing protein 0.008 0.0074 0.0074
Brugia malayi Latrophilin receptor protein 2 0.0352 0.0479 0.0478
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0035 0.0044
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0072 0.0071
Brugia malayi jmjC domain containing protein 0.0189 0.0237 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Echinococcus granulosus GA binding protein alpha chain 0.0079 0.0072 0.0072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0533 0.0533
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0055 0.0036 0.0035
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0022 0.1323
Trypanosoma brucei heat shock protein 90, putative 0.0052 0.0031 0.0046
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0092
Plasmodium vivax heat shock protein 86, putative 0.0052 0.0031 0.0038
Toxoplasma gondii Hsp90 domain-containing protein 0.0196 0.0246 0.0354
Mycobacterium tuberculosis Probable lipase LipE 0.0411 0.0567 0.0561
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0149 0.0176 0.0605
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.109 0.1578 0.1555
Loa Loa (eye worm) hypothetical protein 0.0127 0.0143 0.0143
Echinococcus multilocularis smad 0.0058 0.0041 0.0041
Schistosoma mansoni smad1 5 8 and 0.0058 0.0041 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0063 0.0217
Brugia malayi ecdysteroid receptor 0.0055 0.0036 0.0035
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0006 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0017 0.0059
Onchocerca volvulus 0.0081 0.0075 0.0241
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Brugia malayi AMP-binding enzyme family protein 0.017 0.0207 0.0207
Onchocerca volvulus Protein ultraspiracle homolog 0.0055 0.0036 0.0104
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1113 0.1611 0.1611
Trypanosoma brucei importin beta-1 subunit, putative 0.0094 0.0094 0.0137
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0055 0.0036 0.0036
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0047 0.0025 0.0028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0028 0.0028
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0043 0.0043
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.015 0.0139
Loa Loa (eye worm) MH2 domain-containing protein 0.0849 0.1219 0.1218
Trichomonas vaginalis alpha-glucosidase, putative 0.0055 0.0037 0.0126
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.015 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Echinococcus multilocularis dihydrofolate reductase 0.6747 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0055 0.0036 0.0035
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0092 0.0091 0.0091
Treponema pallidum replicative DNA helicase (dnaB) 0.0759 0.1084 1
Chlamydia trachomatis recombinase RecA 0.0212 0.027 0.0203
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0011 0.0038
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0149 0.0176 0.0175
Echinococcus granulosus cpg binding protein 0.0095 0.0096 0.0096
Onchocerca volvulus 0.0061 0.0046 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0071 0.0243
Echinococcus granulosus tumor protein p63 0.3462 0.5108 0.5108
Echinococcus granulosus lysine specific demethylase 5A 0.0079 0.0072 0.0072
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0063 0.0217
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0389 0.0533 0.0533
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0043 0.0147
Echinococcus multilocularis Smad4 0.0058 0.0041 0.0041
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.005 0.0029 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.0055 0.0037 0.0126
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0055 0.0036 0.0035
Mycobacterium tuberculosis Probable esterase LipL 0.0411 0.0567 0.0561
Giardia lamblia Grp94/Hsp90 0.0048 0.0027 0.1924
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0029 0.0023
Brugia malayi AMP-binding enzyme family protein 0.017 0.0207 0.0207
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.4602 0.6807 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0055 0.0037 0.0571
Onchocerca volvulus 0.0056 0.0038 0.0113
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0011 0.0016
Toxoplasma gondii HEAT repeat-containing protein 0.0094 0.0094 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0411 0.0567 0.0566
Echinococcus multilocularis ecdysone induced protein 78C 0.0055 0.0036 0.0036
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.4602 0.6807 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0051 0.003 0.003
Echinococcus granulosus lamin 0.0081 0.0075 0.0075
Brugia malayi Probable ClpP-like protease 0.0077 0.0068 0.0068
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.005 0.0029 0.0017
Echinococcus granulosus intermediate filament protein 0.0081 0.0075 0.0075
Loa Loa (eye worm) choline O-acetyltransferase 0.0042 0.0018 0.0017
Trichomonas vaginalis importin beta-1, putative 0.0076 0.0068 0.0231
Brugia malayi hypothetical protein 0.015 0.0178 0.0177
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0679 0.0966 0.0965
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0055 0.0036 0.0035
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0029 0.0002
Brugia malayi Muscleblind-like protein 0.0165 0.0201 0.02
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0056 0.0074
Schistosoma mansoni hypothetical protein 0.0082 0.0077 0.0077
Trichomonas vaginalis antibiotic synthetase, putative 0.005 0.0029 0.0098
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Schistosoma mansoni retinoic acid receptor RXR 0.0055 0.0036 0.0035
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0043 0.0147
Loa Loa (eye worm) beta-lactamase 0.0411 0.0567 0.0566
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0018 0.0025
Brugia malayi Endoplasmin precursor 0.0052 0.0031 0.0031
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1739 0.2544 0.2543
Trichomonas vaginalis chromobox protein, putative 0.0139 0.0162 0.0557
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0011 0.0011
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.017 0.0207 0.0201
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0173 0.0212 0.0212
Schistosoma mansoni niemann-pick C1 (NPC1) 0.022 0.0282 0.0282
Leishmania major hypothetical protein, conserved 0.0411 0.0567 0.0832
Trichomonas vaginalis D-aminoacylase, putative 0.0411 0.0567 0.1953
Loa Loa (eye worm) hypothetical protein 0.1113 0.1611 0.1611
Loa Loa (eye worm) hypothetical protein 0.0411 0.0567 0.0566
Loa Loa (eye worm) hypothetical protein 0.0127 0.0143 0.0143
Schistosoma mansoni hypothetical protein 0.0352 0.0479 0.0478
Echinococcus granulosus lysosomal alpha glucosidase 0.067 0.0952 0.0952
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.008 0.0255
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0075 0.0075
Leishmania major carnitine/choline acetyltransferase, putative 0.0042 0.0018 0.0025
Schistosoma mansoni hypothetical protein 0.0031 0.0001 0.0001
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0031 0.0046
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0041 0.0015 0.0022
Loa Loa (eye worm) fli-1 protein 0.024 0.0312 0.0312
Plasmodium vivax importin-beta 2, putative 0.0094 0.0094 0.013
Brugia malayi SET domain containing protein 0.0034 0.0005 0.0005
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0041 0.0051
Leishmania major alpha glucosidase II subunit, putative 0.0149 0.0176 0.0258
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0041 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0286 0.038 0.038
Trypanosoma brucei importin beta-1 subunit, putative 0.0094 0.0094 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0035 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0091 0.0313
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Mycobacterium leprae PROBABLE SIGNAL PEPTIDASE I LEPB (SPASE I) (LEADER PEPTIDASE I). 0.0239 0.0311 0.0285
Leishmania major carnitine palmitoyltransferase-like protein 0.0042 0.0018 0.0025
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0006 0.0008
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Plasmodium falciparum ataxin-2 like protein, putative 0.0184 0.0228 0.0327
Schistosoma mansoni hypothetical protein 0.009 0.0088 0.0088
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0006 0.0006
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.0042 0.0018 0.0018
Loa Loa (eye worm) MH1 domain-containing protein 0.0058 0.0041 0.004
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0075 0.0075
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0646 0.0917 0.1347
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0091 0.009 0.0131
Leishmania major 4-coumarate:coa ligase-like protein 0.017 0.0207 0.0304
Trypanosoma cruzi heat shock protein 85, putative 0.0044 0.002 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0251 0.0328 0.0328
Entamoeba histolytica Ran family GTPase 0.0047 0.0025 0.0347
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0018 0.0025
Brugia malayi F/Y-rich N-terminus family protein 0.0058 0.0041 0.0041
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0043 0.3945
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0411 0.0567 0.0561
Loa Loa (eye worm) hypothetical protein 0.0252 0.033 0.033
Loa Loa (eye worm) MH2 domain-containing protein 0.0058 0.0041 0.004
Schistosoma mansoni hypothetical protein 0.0352 0.0479 0.0478
Trichomonas vaginalis chromobox protein, putative 0.0084 0.008 0.0273
Schistosoma mansoni tar DNA-binding protein 0.0653 0.0927 0.0927
Entamoeba histolytica acyl-CoA synthetase, putative 0.017 0.0207 0.3673
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0063 0.0217
Trichomonas vaginalis penicillin-binding protein, putative 0.0411 0.0567 0.1953
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.6656 0.9864 0.9864
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0042 0.0061
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Echinococcus multilocularis protein patched 0.0093 0.0093 0.0093
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.005 0.0029 0.0023
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0043 0.0018 0.0013
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0043 0.0153
Trichomonas vaginalis antibiotic synthetase, putative 0.005 0.0029 0.0098
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0306 0.041 0.0602
Brugia malayi AMP-binding enzyme family protein 0.017 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.017 0.0207 0.0207
Echinococcus granulosus FTZ F1 alpha 0.0055 0.0036 0.0036
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.0366 0.0366
Brugia malayi steroid hormone receptor 0.0055 0.0036 0.0035
Echinococcus multilocularis muscleblind protein 0.0165 0.0201 0.0201
Echinococcus granulosus sterol regulatory element binding protein 0.0093 0.0093 0.0093
Treponema pallidum signal peptidase I (sip) 0.0239 0.0311 0.2686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Schistosoma mansoni hypothetical protein 0.0132 0.0151 0.0151
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0035 0.012
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0042 0.0061
Plasmodium vivax endoplasmin, putative 0.0052 0.0031 0.0038
Mycobacterium ulcerans hypothetical protein 0.017 0.0207 0.0196
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0092 0.0091 0.0134
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0013 0.0013
Echinococcus multilocularis lysosomal alpha glucosidase 0.067 0.0952 0.0952
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.005 0.0029 0.0042
Brugia malayi hypothetical protein 0.0276 0.0366 0.0366
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0011 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0411 0.0567 0.0566
Brugia malayi Dihydrofolate reductase 0.6747 1 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0035 0.0044
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.0091 0.0091
Schistosoma mansoni smad 0.0058 0.0041 0.004
Brugia malayi Bromodomain containing protein 0.0067 0.0054 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0653 0.0927 0.0927
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0127 0.0143 0.0075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0017 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0042 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0031 0.0107
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0079 0.0072 0.0072
Leishmania major hypothetical protein, conserved 0.0031 0.0001 0.0001
Mycobacterium ulcerans thymidylate synthase 0.109 0.1578 0.1568
Treponema pallidum signal peptidase I 0.0239 0.0311 0.2686
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0068 0.0057
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0032 0.0002 0.0002
Trypanosoma brucei heat shock protein, putative 0.0052 0.0031 0.0046
Trichomonas vaginalis alpha-glucosidase, putative 0.0149 0.0176 0.0605
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0041 0.0015 0.0015
Echinococcus multilocularis zinc finger protein 0.0049 0.0028 0.0028
Toxoplasma gondii ABC1 family protein 0.0411 0.0567 0.0825
Toxoplasma gondii exonuclease III APE 0.0059 0.0043 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0017 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.017 0.0207 0.0196
Echinococcus multilocularis lysosomal alpha glucosidase 0.067 0.0952 0.0952
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0056 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0004 0.0013
Schistosoma mansoni chromobox protein 0.0139 0.0162 0.0162
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0017 0.0017
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0042 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0036 0.0036
Loa Loa (eye worm) AMP-binding enzyme family protein 0.005 0.0029 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0042 0.0143
Trypanosoma cruzi hypothetical protein, conserved 0.0253 0.0331 0.0486
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Mycobacterium tuberculosis Conserved protein 0.0411 0.0567 0.0561
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0082 0.0077 0.0077
Onchocerca volvulus 0.0054 0.0035 0.0103
Schistosoma mansoni choline o-acyltransferase 0.0042 0.0018 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Brugia malayi CXXC zinc finger family protein 0.0086 0.0083 0.0082
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0029 0.0023
Onchocerca volvulus 0.0274 0.0362 0.1232
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.4602 0.6807 1
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0034 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0403 0.0554 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0091 0.0313
Brugia malayi Cytochrome P450 family protein 0.0033 0.0004 0.0003
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0411 0.0567 0.0561
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0022 0.0297
Schistosoma mansoni coup transcription factor 0.0055 0.0036 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0076 0.0068 0.0231
Schistosoma mansoni acetyl-CoA synthetase 0.005 0.0029 0.0028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0389 0.0533 0.0533
Trichomonas vaginalis heat shock protein, putative 0.0038 0.001 0.0034
Trypanosoma brucei Heat shock protein 83, putative 0.0052 0.0031 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0036 0.0035
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.109 0.1578 0.1573
Schistosoma mansoni patched 1 0.0093 0.0093 0.0093
Brugia malayi photoreceptor-specific nuclear receptor 0.0055 0.0036 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Echinococcus granulosus Protein patched homolog 1 0.0093 0.0093 0.0093
Echinococcus granulosus expressed conserved protein 0.0204 0.0258 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0036 0.0035
Leishmania major heat shock protein 83-1 0.0052 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0165 0.0201 0.02
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.015 0.022
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.005 0.0029 0.0034
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.0231 0.0298 0.0298
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.005 0.0029 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0002 0.0005
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0042 0.0053
Trypanosoma brucei PAB1-binding protein , putative 0.0184 0.0228 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0055 0.0036 0.0035
Entamoeba histolytica hypothetical protein 0.0076 0.0068 0.1128
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0149 0.0176 0.3103
Leishmania major 4-coumarate:coa ligase-like protein 0.017 0.0207 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0653 0.0927 0.0927
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0055 0.0036 0.0036
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0111 0.0119 0.0175
Brugia malayi CHD4 protein 0.0032 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0406 0.0559 0.0559
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0038 0.0038
Leishmania major GTP-binding protein, putative 0.0047 0.0025 0.0036
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0011 0.0006
Loa Loa (eye worm) hypothetical protein 0.0598 0.0844 0.0844
Brugia malayi Bromodomain containing protein 0.0162 0.0196 0.0196
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.0231 0.0298 0.0298
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0058 0.0041 0.0041
Onchocerca volvulus Huntingtin homolog 0.0252 0.033 0.1121
Entamoeba histolytica heat shock protein 90, putative 0.0052 0.0031 0.0471
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0092 0.0091 0.0134
Loa Loa (eye worm) hypothetical protein 0.0679 0.0966 0.0965
Schistosoma mansoni hypothetical protein 0.0999 0.1442 0.1442
Leishmania major acetyl-CoA synthetase, putative 0.005 0.0029 0.0042
Leishmania major hypothetical protein, conserved 0.0184 0.0228 0.0334
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0042 0.0018 0.0025
Trypanosoma cruzi Heat shock protein 83, putative 0.0052 0.0031 0.0046
Echinococcus multilocularis tar DNA binding protein 0.0653 0.0927 0.0927
Schistosoma mansoni thyroid hormone receptor 0.0187 0.0232 0.0232
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0029 0.0017
Plasmodium falciparum phd finger protein, putative 0.0058 0.0041 0.0051
Schistosoma mansoni thyroid hormone receptor 0.0187 0.0232 0.0232
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.0059 0.0059
Schistosoma mansoni alpha glucosidase 0.0149 0.0176 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Schistosoma mansoni hypothetical protein 0.0056 0.0038 0.0038
Plasmodium falciparum acyl-CoA synthetase 0.0127 0.0143 0.0202
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0034 0.0006 0.0006
Trichomonas vaginalis sucrase-isomaltase, putative 0.0149 0.0176 0.0605
Onchocerca volvulus 0.0081 0.0075 0.0241
Mycobacterium leprae Probable lipase LipE 0.0411 0.0567 0.0541
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0004 0.0003
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.0042 0.0018 0.0017
Loa Loa (eye worm) bromodomain containing protein 0.004 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0036 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0055 0.0036 0.0035
Echinococcus granulosus chromobox protein 1 0.0139 0.0162 0.0162
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0065 0.0052 0.0075
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0042 0.0061
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0352 0.0479 0.0479
Brugia malayi hypothetical protein 0.0252 0.033 0.033
Schistosoma mansoni smad1 5 8 and 0.0058 0.0041 0.004
Brugia malayi AMP-binding enzyme family protein 0.005 0.0029 0.0028
Echinococcus multilocularis cpg binding protein 0.0095 0.0096 0.0096
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0047 0.0025 0.0036
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0055 0.0036 0.0035
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.005 0.0029 0.0017
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.017 0.0207 0.0181
Echinococcus granulosus geminin 0.0876 0.1259 0.1259
Trypanosoma brucei hypothetical protein, conserved 0.0253 0.0331 0.0486
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0055 0.0037 0.0054
Brugia malayi Hsp90 protein 0.0034 0.0006 0.0005
Leishmania major glycosyl hydrolase-like protein 0.0055 0.0037 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0184 0.0228 0.0327
Loa Loa (eye worm) acetyltransferase 0.0173 0.0212 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Mycobacterium ulcerans esterase/lipase LipP 0.0411 0.0567 0.0556
Brugia malayi nuclear receptor NHR-88 0.0055 0.0036 0.0035
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0055 0.0037 0.0054
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.4602 0.6807 1
Brugia malayi MH1 domain containing protein 0.0032 0.0002 0.0002
Echinococcus multilocularis musashi 0.0081 0.0075 0.0075
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0127 0.0143 0.0132
Echinococcus granulosus chromobox protein 1 0.0139 0.0162 0.0162
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.005 0.0029 0.0017
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0047 0.0025 0.0024
Onchocerca volvulus 0.0042 0.0018 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0036 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.017 0.0207 0.0196
Trypanosoma brucei hypothetical protein, conserved 0.0411 0.0567 0.0832
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0036 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0411 0.0567 0.0825
Schistosoma mansoni heat shock protein 0.0052 0.0031 0.0031
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0149 0.0176 0.025
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0212 0.027 0.23
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0011 0.0011
Leishmania major hypothetical protein, conserved 0.0041 0.0015 0.0022
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0043 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0093 0.032
Loa Loa (eye worm) hypothetical protein 0.0276 0.0366 0.0366
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.6747 1 1
Loa Loa (eye worm) twinkle helicase 0.0217 0.0277 0.0277
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0043 0.0062
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0055 0.0036 0.0104
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.017 0.0207 0.0196
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0411 0.0567 0.0556
Onchocerca volvulus Bile acid receptor homolog 0.0055 0.0036 0.0104
Loa Loa (eye worm) hypothetical protein 0.015 0.0178 0.0177
Brugia malayi Ets-domain containing protein 0.0079 0.0072 0.0072
Brugia malayi thymidylate synthase 0.109 0.1578 0.1578
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0006 0.0006
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0042 0.0061
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0055 0.0036 0.0035
Onchocerca volvulus 0.1979 0.2901 1
Echinococcus multilocularis GA binding protein alpha chain 0.0079 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0078 0.0071 0.0071
Echinococcus granulosus GPCR family 2 0.0352 0.0479 0.0479
Brugia malayi RNA binding protein 0.0653 0.0927 0.0927
Plasmodium falciparum importin beta, putative 0.0094 0.0094 0.0129
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0055 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0411 0.0567 0.0566
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0011 0.0016
Brugia malayi Bromodomain containing protein 0.0082 0.0077 0.0077
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0029 0.0017
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0759 0.1084 0.1074
Trichomonas vaginalis D-aminoacylase, putative 0.0411 0.0567 0.1953
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0055 0.0036 0.0035
Schistosoma mansoni smad1 5 8 and 0.0058 0.0041 0.004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.0091 0.0091
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0251 0.0328 0.0328
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0352 0.0479 0.0478
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0068 0.0092
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0068 0.0042
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0389 0.0533 0.0533
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0006 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.017 0.0207 0.3673
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0352 0.0479 0.0479
Onchocerca volvulus 0.0042 0.0018 0.0041
Brugia malayi MH2 domain containing protein 0.0849 0.1219 0.1218
Brugia malayi follicle stimulating hormone receptor 0.0295 0.0394 0.0394
Brugia malayi RNA recognition motif domain containing protein 0.0653 0.0927 0.0927
Trypanosoma brucei acetyl-CoA synthetase, putative 0.005 0.0029 0.0042
Chlamydia trachomatis dihydrofolate reductase 0.6747 1 1
Echinococcus multilocularis Niemann Pick C1 protein 0.031 0.0416 0.0416
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.6109 0.9049 0.9049
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0035 0.012
Schistosoma mansoni microtubule-associated protein tau 0.6297 0.933 0.933
Schistosoma mansoni intermediate filament proteins 0.0081 0.0075 0.0075
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0042 0.0018 0.0017
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.005 0.0029 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0028 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0653 0.0927 0.0927
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0035 0.0121
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0403 0.0554 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0071 0.0243
Entamoeba histolytica hypothetical protein 0.0403 0.0554 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0389 0.0533 0.0533
Schistosoma mansoni hypothetical protein 0.009 0.0088 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0507 0.0709 0.0709

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 8 ug ml-1 Antibacterial activity against Escherichia coli MG1655 harboring lepB P84L mutant after 24 hrs by CLSI broth microdilution method ChEMBL. 21630667
MIC (functional) > 64 ug ml-1 Antibacterial activity against Escherichia coli MG1655 after 24 hrs by CLSI broth microdilution method ChEMBL. 21630667

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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