Detailed information for compound 1081489

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 337.412 | Formula: C21H23NO3
  • H donors: 4 H acceptors: 3 LogP: 3.57 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](Cc1ccc2c(c1)cccc2)NC[C@@H](c1cc(O)cc(c1)O)O
  • InChi: 1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21-/m0/s1
  • InChiKey: LGUXLVJQUKRZBO-QKKBWIMNSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adrenoceptor beta 2, surface Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0348 0.0529
Echinococcus multilocularis serotonin receptor 0.0038 0.0235 0.0235
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.019 0.2067 0.3144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Brugia malayi Dopamine receptor 0.0038 0.0235 0.0358
Brugia malayi nuclear receptor NHR-88 0.0115 0.1156 0.1759
Trichomonas vaginalis cation-transporting ATPase, putative 0.0022 0.004 0.0064
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0235 0.0235
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0243 0.2696 0.4409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0162 0.0507
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0464 0.0706
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0091 0.0873 0.0873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0117 0.0344
Mycobacterium ulcerans hypothetical protein 0.0042 0.0289 0.1093
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0039 0.0255 0.0255
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0348 0.2372
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0235 0.0235
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.003 0.0139 0.1349
Echinococcus granulosus glycine receptor subunit beta 0.0039 0.0255 0.0417
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0068 0.06 0.4202
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0591 0.064
Echinococcus granulosus Ankyrin 0.0031 0.0149 0.0243
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0217 0.071
Loa Loa (eye worm) nuclear receptor NHR-67 0.0115 0.1156 0.1759
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.0755 0.5335
Schistosoma mansoni amine GPCR 0.0038 0.0235 0.0255
Brugia malayi ABC transporter family protein 0.004 0.0263 0.0401
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0081 0.0676
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0205 0.0205
Echinococcus granulosus pyruvate kinase 0.0068 0.0602 0.0984
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0166 0.0166
Onchocerca volvulus 0.0037 0.0221 0.0797
Entamoeba histolytica P-glycoprotein 5, putative 0.004 0.0263 0.2136
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0348 0.0569
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0039 0.0255 0.0417
Schistosoma mansoni cation-transporting atpase worm 0.0022 0.004 0.0043
Echinococcus multilocularis lamin 0.0057 0.0464 0.0464
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0037 0.004
Brugia malayi small heat shock protein 0.0566 0.6575 1
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0025 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0102 0.0289
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0056 0.0451 0.0737
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0092 0.0887 1
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0374 0.0374
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0187 0.2029 0.3086
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0205 0.0312
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0146 0.0238
Echinococcus multilocularis cpg binding protein 0.0032 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0031 0.0149 0.0226
Brugia malayi hypothetical protein 0.0128 0.1321 0.201
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0225 0.2476 0.9557
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.004 0.0265 0.1764
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0022 0.004 0.0205
Schistosoma mansoni nuclear hormone receptor 0.0115 0.1156 0.1252
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0022 0.004 0.0073
Entamoeba histolytica P-glyco protein 6, putative 0.004 0.0263 0.2136
Schistosoma mansoni zinc finger protein 0.0115 0.1156 0.1252
Echinococcus granulosus orexin receptor type 2 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis nAChR subunit 0.0021 0.0037 0.0037
Schistosoma mansoni multidrug resistance protein 0.004 0.0265 0.0286
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0022 0.004 0.0061
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0243 0.2696 0.4101
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0025 0.006
Schistosoma mansoni aryl hydrocarbon receptor 0.0103 0.1013 0.1096
Onchocerca volvulus 0.0057 0.0464 0.1671
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0107 0.0621
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Echinococcus multilocularis sodium and chloride dependent glycine 0.0032 0.017 0.017
Brugia malayi conserved hypotetical protein 0.0115 0.1156 0.1759
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0091 0.0873 0.619
Onchocerca volvulus 0.0037 0.0221 0.0797
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.004 0.0263 0.0263
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0097 0.0951 0.374
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.1293 0.4947
Leishmania major pentamidine resistance protein 1 0.004 0.0265 0.1764
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Brugia malayi RE15519p 0.0038 0.0235 0.0358
Echinococcus multilocularis nAChR subunit 0.0039 0.0255 0.0255
Echinococcus granulosus hypothetical protein 0.0038 0.0235 0.0385
Echinococcus multilocularis cation transporting atpase worm 0.0022 0.004 0.004
Onchocerca volvulus 0.0039 0.0255 0.0918
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.057 0.0616
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0022 0.004 0.004
Echinococcus granulosus geminin 0.0522 0.6045 0.9885
Trichomonas vaginalis cation-transporting ATPase, putative 0.0043 0.0302 0.1017
Brugia malayi photoreceptor-specific nuclear receptor 0.0243 0.2696 0.4101
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0591 0.064
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0235 0.0235
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0039 0.0255 0.0388
Schistosoma mansoni hypothetical protein 0.0133 0.1381 0.1495
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0102 0.0289
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.004 0.0263 0.0877
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0464 0.0706
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0225 0.2476 0.9557
Toxoplasma gondii ABC1 family protein 0.0037 0.0221 0.2303
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.004 0.0265 0.0402
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0235 0.0255
Schistosoma mansoni hypothetical protein 0.0049 0.0374 0.0404
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0065 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0221 0.0337
Brugia malayi nuclear hormone receptor family member nhr-6 0.0115 0.1156 0.1759
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.4979 0.4979
Schistosoma mansoni adenoreceptor 0.0038 0.0235 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0238
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0056 0.0451 0.4955
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Brugia malayi hypothetical protein 0.0032 0.017 0.0258
Loa Loa (eye worm) LGC-31 protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Echinococcus granulosus muscleblind protein 0.0151 0.1591 0.2602
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0032 0.017 0.0536
Schistosoma mansoni hypothetical protein 0.0055 0.0439 0.0475
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0022 0.004 0.0069
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Trypanosoma brucei p-glycoprotein 0.004 0.0265 0.1795
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.1141 0.4357
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0221 0.0724
Brugia malayi Cathepsin L-like precursor 0.0035 0.0205 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Leishmania major proton motive ATPase, putative 0.0022 0.004 0.0129
Schistosoma mansoni amine GPCR 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0755 0.5353
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0068 0.06 0.4202
Loa Loa (eye worm) hypothetical protein 0.0024 0.0065 0.0099
Trichomonas vaginalis ABC transporter, putative 0.004 0.0263 0.0877
Brugia malayi Cytochrome P450 family protein 0.002 0.0026 0.0039
Schistosoma mansoni neuropeptide receptor 0.0038 0.0235 0.0255
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.017 0.0184
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.004 0.0263 0.0877
Echinococcus granulosus tar DNA binding protein 0.0067 0.0591 0.0967
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0115 0.1156 0.4163
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.019 0.2067 0.3144
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0166 0.0271
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.004 0.0265 0.1764
Onchocerca volvulus Putative nachr subunit 0.0039 0.0255 0.0918
Brugia malayi bHLH-PAS transcription factor 0.0076 0.0693 0.1054
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0205 0.0666
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0022 0.004 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0337
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0378 0.0574
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0243 0.2696 0.4101
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0337
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0221 0.0221
Brugia malayi hypothetical protein 0.0053 0.042 0.0638
Onchocerca volvulus 0.0035 0.0205 0.074
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Leishmania major P-type H -ATPase, putative 0.0043 0.0302 0.2038
Schistosoma mansoni biogenic amine receptor 0.0038 0.0235 0.0255
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.004 0.0263 0.0263
Brugia malayi multidrug resistance related protein 1 0.004 0.0265 0.0402
Brugia malayi orphan nuclear receptor NR2E1 0.0115 0.1156 0.1759
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0348 0.24
Echinococcus granulosus ecdysone induced protein 78C 0.0243 0.2696 0.4409
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0221 0.0239
Onchocerca volvulus 0.0076 0.0693 0.2494
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0844 0.1284
Echinococcus multilocularis dna polymerase kappa 0.002 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus 0.0021 0.0037 0.0132
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Echinococcus granulosus g protein coupled receptor 0.0038 0.0235 0.0385
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.004 0.0265 0.1764
Onchocerca volvulus 0.003 0.0147 0.0528
Brugia malayi tailless protein 0.0115 0.1156 0.1759
Toxoplasma gondii hypothetical protein 0.0032 0.017 0.1705
Echinococcus multilocularis pyruvate kinase 0.0068 0.0602 0.0602
Brugia malayi Melatonin receptor type 1A 0.0038 0.0235 0.0358
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.004 0.0263 0.0431
Giardia lamblia GTOR 0.0047 0.0348 0.3126
Toxoplasma gondii P-type ATPase PMA1 0.0043 0.0302 0.3237
Loa Loa (eye worm) hypothetical protein 0.0128 0.1321 0.201
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0102 0.0289
Brugia malayi Cation transporter family protein 0.0039 0.0255 0.0388
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0069 0.0614 0.1004
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0039 0.0255 0.0388
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0205 0.0222
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0235 0.0358
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0424 0.1459
Treponema pallidum sodium- and chloride- dependent transporter 0.019 0.2067 0.8378
Toxoplasma gondii pyruvate kinase PyKII 0.0035 0.0203 0.2086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0069 0.0105
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0235 0.0358
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0221 0.0239
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0081 0.0167
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0068 0.06 0.2098
Onchocerca volvulus 0.0159 0.1686 0.6069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Trichomonas vaginalis abcb9, putative 0.004 0.0263 0.0877
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0221 0.0362
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0424 0.3853
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0443 0.5099 0.8338
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Schistosoma mansoni hypothetical protein 0.0024 0.0068 0.0073
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0068 0.0111
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0107 0.1065 0.1065
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0025 0.006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0235 0.0235
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0166 0.1662
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0221 0.0776
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0022 0.0037
Schistosoma mansoni hypothetical protein 0.0107 0.1061 0.1148
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0061
Loa Loa (eye worm) cysteine protease 0.0035 0.0205 0.0312
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0081 0.024
Brugia malayi cathepsin L-like precursor 0.0024 0.0065 0.0099
Brugia malayi Nuclear hormone receptor E75 0.0115 0.1156 0.1759
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0022 0.004 0.0129
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0092 0.0887 0.1451
Echinococcus granulosus cation transporting ATPase 13A1 0.0022 0.004 0.0065
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0146 0.0157
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0173 0.1097
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0243 0.2696 0.4101
Echinococcus multilocularis aryl hydrocarbon receptor 0.0027 0.0102 0.0102
Trichomonas vaginalis taga, putative 0.004 0.0263 0.0877
Echinococcus granulosus fmrfamide receptor 0.0038 0.0235 0.0385
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0235 0.0235
Schistosoma mansoni pyruvate kinase 0.0035 0.0203 0.0219
Brugia malayi Cathepsin L-like precursor 0.0024 0.0065 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Onchocerca volvulus 0.0035 0.0205 0.074
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0221 0.0724
Echinococcus multilocularis pyruvate kinase 0.0035 0.0203 0.0203
Echinococcus multilocularis cysteine protease 0.0035 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.004 0.0263 0.0263
Trypanosoma brucei pyruvate kinase 1, putative 0.0068 0.0602 0.424
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0099 0.0966 0.1469
Schistosoma mansoni hypothetical protein 0.0049 0.0374 0.0404
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0755 0.0755
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0102 0.0289
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0102 0.0289
Trichomonas vaginalis abcb9, putative 0.004 0.0263 0.0877
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0079 0.0724 0.0783
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0221 0.1482
Schistosoma mansoni pyruvate kinase 0.0068 0.0602 0.0651
Loa Loa (eye worm) hypothetical protein 0.0081 0.0755 0.1149
Echinococcus granulosus netrin receptor unc 5 0.003 0.0146 0.0238
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0235 0.0235
Brugia malayi Cathepsin L-like precursor 0.0035 0.0205 0.0312
Echinococcus granulosus pyruvate kinase 0.0035 0.0203 0.0331
Schistosoma mansoni multidrug resistance protein 0.004 0.0265 0.0286
Entamoeba histolytica hypothetical protein 0.0114 0.1152 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0354 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0232 0.0763
Leishmania major cathepsin L-like protease 0.0035 0.0205 0.1334
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0243 0.2696 0.4101
Entamoeba histolytica hypothetical protein 0.0114 0.1152 1
Schistosoma mansoni biogenic amine receptor 0.0038 0.0235 0.0255
Schistosoma mansoni coup transcription factor 0.0243 0.2696 0.2918
Brugia malayi nuclear receptor NHR-88 0.0243 0.2696 0.4101
Brugia malayi neuropeptide F receptor 0.0038 0.0235 0.0358
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.1141 0.4357
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0027 0.0102 0.0289
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0022 0.004 0.0061
Schistosoma mansoni lamin 0.0057 0.0464 0.0502
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0755 0.1149
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Giardia lamblia Multidrug resistance-associated protein 1 0.004 0.0265 0.2326
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0069 0.0192
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Schistosoma mansoni nuclear receptor 0.0115 0.1156 0.1252
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0233 0.1532
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0023 0.0055 0.0128
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.017 0.0184
Brugia malayi beta-lactamase family protein 0.0037 0.0221 0.0337
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0092 0.0887 0.3545
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0128 0.1321 0.2161
Brugia malayi Nuclear hormone receptor-like 1 0.0128 0.1321 0.201
Brugia malayi glutathione reductase 0.005 0.0378 0.0574
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0133 0.1381 0.2259
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.0258
Leishmania major trypanothione reductase 0.005 0.0378 0.2587
Schistosoma mansoni lamin 0.0057 0.0464 0.0502
Echinococcus granulosus Nuclear hormone receptor HR96 0.0115 0.1156 0.1891
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0061
Entamoeba histolytica ATP-binding cassette protein, putative 0.004 0.0265 0.2145
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0069 0.0341
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0243 0.2696 0.2918
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.2029 0.2196
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0255 0.0388
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0025 0.0027
Schistosoma mansoni neuropeptide receptor 0.0038 0.0235 0.0255
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0022 0.004 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0238
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0243 0.2696 0.2696
Schistosoma mansoni copper ABC transporter ATPase 0.0022 0.004 0.0043
Leishmania major calcium-transporting ATPase, putative 0.0056 0.0451 0.3119
Leishmania major cathepsin L-like protease 0.0135 0.1396 1
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0405 0.0438
Brugia malayi Cathepsin L-like precursor 0.0035 0.0205 0.0312
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0021 0.0037 0.004
Brugia malayi calcium ATPase 0.0026 0.0094 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis geminin 0.0522 0.6045 0.6045
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0424 0.2923
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0235 0.0358
Schistosoma mansoni neuropeptide receptor 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0356
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.1293 0.4947
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0039 0.0255 0.0417
Schistosoma mansoni retinoic acid receptor RXR 0.0443 0.5099 0.5518
Brugia malayi Nuclear hormone receptor-like 1 0.0243 0.2696 0.4101
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.0258
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0121 0.1228 0.1329
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0243 0.2696 0.4409
Echinococcus multilocularis neuropeptide s receptor 0.0528 0.6116 0.6116
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0039 0.0255 0.0417
Echinococcus granulosus ubiquitin specific protease 41 0.0081 0.0755 0.1235
Echinococcus granulosus glycine receptor subunit alpha 1 0.0039 0.0255 0.0417
Schistosoma mansoni ATPase 0.0091 0.0873 0.0944
Brugia malayi Calcitonin receptor-like protein seb-1 0.0156 0.1653 0.2514
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0025 0.0022
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0591 0.0899
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0788 0.924 1
Brugia malayi ecdysone receptor 0.0115 0.1156 0.1759
Plasmodium falciparum multidrug resistance protein 1 0.004 0.0263 0.279
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Echinococcus multilocularis nuclear receptor nhr 48 0.0115 0.1156 0.1156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0755 0.2663
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0235 0.0358
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0039 0.0255 0.0255
Onchocerca volvulus 0.0038 0.0235 0.0847
Plasmodium vivax multidrug resistance protein 1, putative 0.004 0.0263 0.279
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0223 0.2463 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Loa Loa (eye worm) norepinephrine transporter 0.019 0.2067 0.3144
Plasmodium falciparum transporter, putative 0.0032 0.017 0.1705
Trichomonas vaginalis ABC transporter, putative 0.004 0.0263 0.0877
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0873 0.309
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0026 0.0039
Toxoplasma gondii P-type ATPase4, putative 0.0069 0.0614 0.6842
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0235 0.0255
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0235 0.0235
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0056 0.0451 0.0451
Loa Loa (eye worm) multidrug resistance protein 3 0.004 0.0263 0.0401
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0187 0.2029 0.2029
Plasmodium vivax amine transporter, putative 0.0032 0.017 0.1705
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0243 0.2696 0.4409
Mycobacterium leprae Probable pyruvate kinase PykA 0.0068 0.0602 0.2306
Loa Loa (eye worm) hypothetical protein 0.003 0.0139 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Loa Loa (eye worm) hypoxia-induced factor 1 0.0318 0.3592 0.5463
Onchocerca volvulus 0.0052 0.0405 0.1458
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.042 0.4595
Loa Loa (eye worm) hypothetical protein 0.0128 0.1321 0.201
Trypanosoma cruzi P-type H+-ATPase, putative 0.0043 0.0302 0.2038
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.004 0.0263 0.0401
Echinococcus multilocularis pyruvate kinase 0.0054 0.0429 0.0429
Onchocerca volvulus 0.025 0.2778 1
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0221 0.0776
Onchocerca volvulus 0.0038 0.0235 0.0847
Trypanosoma brucei cytochrome P450, putative 0.002 0.0026 0.0065
Schistosoma mansoni ATPase 0.0091 0.0873 0.0944
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0424 0.2923
Loa Loa (eye worm) hypothetical protein 0.004 0.0265 0.0402
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0221 0.0776
Onchocerca volvulus 0.0035 0.0205 0.074
Loa Loa (eye worm) hypothetical protein 0.0473 0.5453 0.8293
Trypanosoma brucei calcium-translocating P-type ATPase 0.0079 0.0724 0.5126
Loa Loa (eye worm) calcium ATPase 0.004 0.0257 0.0391
Loa Loa (eye worm) inositol-1 0.0036 0.0217 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0243 0.2696 0.4101
Brugia malayi Cytochrome P450 family protein 0.002 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Schistosoma mansoni hypothetical protein 0.0038 0.0235 0.0255
Chlamydia trachomatis pyruvate kinase 0.0068 0.0602 0.2319
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0378 0.0378
Brugia malayi hypothetical protein 0.0344 0.3912 0.595
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0025 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Echinococcus granulosus Na:K ATPase alpha subunit 0.0107 0.1065 0.1741
Entamoeba histolytica hypothetical protein 0.0114 0.1152 1
Brugia malayi hypothetical protein 0.0115 0.1156 0.1759
Echinococcus granulosus nuclear factor of activated T cells 5 0.0155 0.1645 0.269
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0039 0.0255 0.0388
Trypanosoma brucei multidrug resistance protein E 0.004 0.0265 0.1795
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0205 0.0312
Plasmodium falciparum amino acid transporter, putative 0.0032 0.017 0.1705
Loa Loa (eye worm) ctsf protein 0.0035 0.0205 0.0312
Schistosoma mansoni opsin-like receptor 0.0038 0.0235 0.0255
Leishmania major cytochrome p450-like protein 0.002 0.0026 0.0028
Echinococcus granulosus cation transporting atpase worm 0.0022 0.004 0.0065
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0235 0.0847
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0039 0.0255 0.0255
Brugia malayi Cathepsin L-like precursor 0.0035 0.0205 0.0312
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.015
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0025 0.0027
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.0258
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0205 0.1334
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0235 0.0235
Echinococcus multilocularis pyruvate kinase 0.0035 0.0203 0.0203
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0221 0.0745
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0022
Echinococcus multilocularis lamin dm0 0.0057 0.0464 0.0464
Echinococcus multilocularis sodium and chloride dependent glycine 0.0032 0.017 0.017
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0039 0.0255 0.0388
Echinococcus granulosus neuropeptide receptor 0.0038 0.0235 0.0385
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0025 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.042 0.4595
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0235 0.0358
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0348 0.0529
Echinococcus multilocularis musashi 0.0057 0.0464 0.0464
Schistosoma mansoni steroid hormone receptor ad4bp 0.0243 0.2696 0.2918
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0235 0.0358
Trichomonas vaginalis pyruvate kinase, putative 0.0068 0.0602 0.2106
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.004 0.0265 0.1764
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0032 0.017 0.0184
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0038
Echinococcus multilocularis ubiquitin specific protease 41 0.0081 0.0755 0.0755
Brugia malayi GnHR receptor homolog 0.0038 0.0235 0.0358
Trichomonas vaginalis ABC transporter, half transporter, putative 0.004 0.0263 0.0877
Onchocerca volvulus 0.0115 0.1156 0.4163
Onchocerca volvulus 0.0024 0.0065 0.0235
Entamoeba histolytica P-glycoprotein-2, putative 0.004 0.0263 0.2136
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0068 0.06 0.6675
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0023 0.0054 0.0285
Echinococcus granulosus calcium transporting atpase 0.0079 0.0724 0.1184
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Plasmodium falciparum pyruvate kinase 0.0068 0.0602 0.67
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0243 0.2696 0.2696
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0147 0.0224
Brugia malayi G-protein coupled receptor 0.0038 0.0235 0.0358
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0374 0.0374
Mycobacterium leprae Possible regulatory protein 0.0027 0.0102 0.0254
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0039 0.0255 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0155 0.1645 0.1645
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0235 0.0358
Schistosoma mansoni pyruvate kinase 0.0068 0.0602 0.0651
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0235 0.0235
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0235 0.0235
Onchocerca volvulus 0.0243 0.2696 0.9706
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0221 0.0724
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0115 0.1156 0.1156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0221 0.0816
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.1141 0.4357
Loa Loa (eye worm) hypothetical protein 0.004 0.0263 0.0401
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0205 0.074
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.004 0.0263 0.094
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0099 0.0966 0.1469
Schistosoma mansoni smdr2 0.004 0.0263 0.0285
Echinococcus granulosus nAChR subunit 0.0039 0.0255 0.0417
Brugia malayi hypothetical protein 0.0034 0.0194 0.0294
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0025 0.0038
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0039 0.0255 0.0276
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0027 0.0102 0.0166
Echinococcus granulosus sodium and chloride dependent glycine 0.0032 0.017 0.0277
Loa Loa (eye worm) hypothetical protein 0.0091 0.0873 0.1327
Echinococcus granulosus GPCR family 2 0.0049 0.0374 0.0611
Onchocerca volvulus 0.0032 0.017 0.0611
Brugia malayi Nuclear hormone receptor E75 0.0115 0.1156 0.1759
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0235 0.0385
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0243 0.2696 0.2918
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi Inositol-1 0.0036 0.0217 0.0331
Onchocerca volvulus 0.0035 0.0205 0.074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.2029 0.2196
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0235 0.0385
Plasmodium vivax pyruvate kinase 2, putative 0.0035 0.0203 0.2086
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0069 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0117 0.0344
Trypanosoma brucei unspecified product 0.002 0.0025 0.006
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.1141 0.4519
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0102 0.0289
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0424 0.1459
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1396 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.1256 0.8981
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.0258
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.004 0.0263 0.0877
Brugia malayi Na,K-ATPase alpha subunit 0.0121 0.1228 0.1867
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0025 0.0025
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0217 0.0217
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.2812 0.4277
Schistosoma mansoni myosin xvIII 0.0038 0.0235 0.0255
Entamoeba histolytica P-glycoprotein-2 0.004 0.0263 0.2136
Mycobacterium ulcerans lipase LipD 0.0037 0.0221 0.0816
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0235 0.0235
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0022 0.004 0.0157
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0225 0.2476 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0217 0.071
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0243 0.2696 0.4101
Leishmania major ABC-thiol transporter 0.004 0.0265 0.1764
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0081 0.024
Trypanosoma cruzi pyruvate kinase 2, putative 0.0068 0.0602 0.4218
Schistosoma mansoni cpg binding protein 0.0032 0.0167 0.0181
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0243 0.2696 0.4101
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0235 0.0385
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.2412 0.3669
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Loa Loa (eye worm) solute carrier family 6 member 4 0.019 0.2067 0.3144
Plasmodium falciparum pyruvate kinase 2 0.0035 0.0203 0.2086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0235 0.0255
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Echinococcus granulosus glycine receptor subunit beta 0.0039 0.0255 0.0417
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0111 0.0111
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.004 0.0257 0.2078
Onchocerca volvulus 0.0038 0.0235 0.0847
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0755 0.2663
Schistosoma mansoni multidrug resistance protein 0.004 0.0265 0.0286
Schistosoma mansoni multidrug resistance protein 0.004 0.0263 0.0285
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0022 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Trypanosoma brucei P-type H+-ATPase, putative 0.0043 0.0302 0.2068
Loa Loa (eye worm) nuclear hormone receptor 0.0115 0.1156 0.1759
Trichomonas vaginalis cation-transporting ATPase, putative 0.0068 0.06 0.2098
Brugia malayi Pyruvate kinase, muscle isozyme 0.0068 0.0602 0.0915
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0755 0.2663
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.004 0.0265 0.0402
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0144 0.0236
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0022 0.004 0.0073
Giardia lamblia ABC transporter, putative 0.004 0.0265 0.2326
Onchocerca volvulus 0.0035 0.0205 0.074
Loa Loa (eye worm) hypothetical protein 0.0159 0.1686 0.2564
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0081 0.024
Trypanosoma cruzi hypothetical protein 0.0023 0.0057 0.0252
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0081 0.0755 0.0817
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0221 0.0776
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0039 0.0255 0.0417
Onchocerca volvulus Protein ultraspiracle homolog 0.0243 0.2696 0.9706
Echinococcus multilocularis transfer RNA-Lys 0.0076 0.0693 0.0693
Loa Loa (eye worm) multidrug resistance-associated protein 0.0024 0.0064 0.0097
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0235 0.0255
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0235 0.0235
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0069 0.0192
Schistosoma mansoni cation-transporting ATPase 0.0022 0.004 0.0043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0115 0.1156 0.1156
Schistosoma mansoni DNA polymerase eta 0.002 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0205 0.212
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0026 0.0028
Echinococcus granulosus lamin dm0 0.0057 0.0464 0.0759
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0217 0.0801
Schistosoma mansoni RAR-like nuclear receptor 0.0243 0.2696 0.2918
Schistosoma mansoni hypothetical protein 0.0522 0.6045 0.6542
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0255 0.0388
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0217 0.1422
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0348 0.2372
Brugia malayi Cation transporter family protein 0.0039 0.0255 0.0388
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0081 0.0676
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Leishmania major pyruvate kinase 0.0068 0.0602 0.4218
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0027 0.0102 0.0102
Brugia malayi Pyruvate kinase, M2 isozyme 0.0068 0.0602 0.0915
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0243 0.2696 0.4101
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0039 0.0255 0.0276
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0235 0.0255
Echinococcus granulosus serotonin receptor 0.0038 0.0235 0.0385
Schistosoma mansoni multidrug resistance protein 0.004 0.0265 0.0286
Loa Loa (eye worm) hypothetical protein 0.0151 0.1591 0.242
Echinococcus granulosus g protein coupled receptor 0.0038 0.0235 0.0385
Onchocerca volvulus 0.0032 0.0166 0.0597
Giardia lamblia MRP-like ABC transporter 0.004 0.0265 0.2326
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.004 0.0257 0.0391
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.015
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.1396 1
Brugia malayi multidrug resistance protein 3 0.004 0.0263 0.0401
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0022
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0021 0.0037 0.0056
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0048 0.0352 0.2403
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.042 0.2893
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0378 0.1384
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0348 0.0348
Echinococcus multilocularis pyruvate kinase 0.0068 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0052 0.0405 0.0616
Echinococcus multilocularis thyroid hormone receptor alpha 0.0376 0.4296 0.4296
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Trypanosoma brucei cation-transporting ATPase, putative 0.0022 0.004 0.0166
Echinococcus granulosus single minded 2 0.0076 0.0693 0.1133
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0235 0.0235
Onchocerca volvulus 0.0027 0.0102 0.0366
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0068 0.06 0.5539
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0205 0.0312
Trichomonas vaginalis set domain proteins, putative 0.0249 0.2775 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0173 0.113
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0234 0.259 1
Plasmodium falciparum calcium-transporting ATPase 0.0079 0.0724 0.8112
Plasmodium falciparum copper-transporting ATPase 0.0022 0.004 0.0205
Plasmodium falciparum thioredoxin reductase 0.005 0.0378 0.4109
Brugia malayi hypothetical protein 0.0114 0.1152 0.1752
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0039 0.0255 0.0255
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0031 0.0153 0.1161
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Echinococcus granulosus somatostatin receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) ACC-1 protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.003 0.0146 0.0221
Loa Loa (eye worm) hypothetical protein 0.0024 0.0069 0.0105
Schistosoma mansoni hypothetical protein 0.0038 0.0235 0.0255
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.1152 0.1884
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.042 0.2893
Leishmania major cathepsin L-like protease 0.0135 0.1396 1
Brugia malayi hypothetical protein 0.0128 0.1321 0.201
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.042 0.4595
Echinococcus granulosus glycine receptor subunit alpha 1 0.0039 0.0255 0.0417
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0173 0.0263
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0279 0.3134 0.4767
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0068 0.0602 0.2257
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0205 0.0666
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0424 0.1459
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0255 0.0388
Echinococcus granulosus glycine receptor subunit alpha 1 0.0039 0.0255 0.0417
Plasmodium vivax calcium-transporting ATPase, putative 0.0092 0.0887 1
Giardia lamblia Pyruvate kinase 0.0035 0.0203 0.1731
Trichomonas vaginalis ABC transporter, putative 0.004 0.0263 0.0877
Loa Loa (eye worm) hypothetical protein 0.0032 0.0166 0.0252
Onchocerca volvulus 0.0038 0.0235 0.0847
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0063 0.0148
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.004 0.0263 0.0431
Loa Loa (eye worm) hypothetical protein 0.0049 0.0374 0.0568
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0107 0.0621
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0025 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Giardia lamblia Multidrug resistance-associated protein 1 0.004 0.0257 0.2256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0232 0.0763
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0025 0.0012
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0203 0.209
Loa Loa (eye worm) hypothetical protein 0.0024 0.0065 0.0099
Loa Loa (eye worm) hypothetical protein 0.0056 0.0452 0.0687
Loa Loa (eye worm) hypothetical protein 0.0024 0.0069 0.0105
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0424 0.4643
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0187 0.2029 0.3318
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.511
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.017 0.0184
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0128 0.1321 0.143
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0243 0.2696 0.4409
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0173 0.113
Mycobacterium ulcerans error-prone DNA polymerase 0.0223 0.2463 1
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.2812 0.4277
Onchocerca volvulus 0.019 0.2067 0.7441
Brugia malayi E1-E2 ATPase family protein 0.0022 0.004 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0238
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.1051 0.7485
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0173 0.0173
Brugia malayi PAS domain containing protein 0.0103 0.1013 0.154
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0025 0.0013
Loa Loa (eye worm) hypothetical protein 0.004 0.0256 0.039
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.004 0.0265 0.2802
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0032 0.017 0.0258
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.2029 0.2196
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0173 0.0283
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi follicle stimulating hormone receptor 0.0279 0.3134 0.4767
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.0614 0.2151
Leishmania major protein kinase, putative 0.0027 0.0107 0.0621
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0056 0.0451 0.3119
Mycobacterium leprae Probable lipase LipE 0.0037 0.0221 0.0745
Entamoeba histolytica P-glycoprotein-1 0.004 0.0263 0.2136
Brugia malayi Cathepsin L-like precursor 0.0024 0.0065 0.0099
Brugia malayi MAP kinase sur-1 0.0054 0.0424 0.0645
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus 0.0038 0.0235 0.0847
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0022 0.004 0.0157
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.1141 0.4357
Schistosoma mansoni sodium/chloride dependent transporter 0.0032 0.017 0.0184
Brugia malayi TAR-binding protein 0.0067 0.0591 0.0899
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0205 0.1334
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0039 0.0255 0.0417
Loa Loa (eye worm) hypothetical protein 0.0057 0.0464 0.0706
Onchocerca volvulus 0.0039 0.0255 0.0918
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0232 0.0763
Echinococcus granulosus multidrug resistance protein 1 0.004 0.0263 0.0431
Loa Loa (eye worm) hypothetical protein 0.0121 0.1228 0.1867
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0063 0.0103
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0602 0.2166
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0221 0.0776
Brugia malayi CXXC zinc finger family protein 0.003 0.0147 0.0223
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0081 0.0755 0.6488
Echinococcus granulosus multidrug resistance associated protein 1 0.004 0.0265 0.0433
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0221 0.0337
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Echinococcus granulosus thyroid hormone receptor alpha 0.0115 0.1156 0.1891
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0424 0.2923
Trypanosoma brucei trypanothione reductase 0.005 0.0378 0.2615
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0235 0.0255
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0069 0.0414
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0235 0.0358
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0221 0.0816
Schistosoma mansoni thyroid hormone receptor 0.0376 0.4296 0.4649
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0187 0.2029 0.3318
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.004 0.0265 0.1764
Schistosoma mansoni ap endonuclease 0.002 0.0022 0.0024
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0255 0.0276
Schistosoma mansoni inositol monophosphatase 0.0036 0.0217 0.0235
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0039 0.0255 0.0388
Schistosoma mansoni thyroid hormone receptor 0.0376 0.4296 0.4649
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Echinococcus multilocularis multidrug resistance associated protein 7 0.004 0.0265 0.0265
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0235 0.0235
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0069 0.0341
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0602 0.2166
Echinococcus granulosus cpg binding protein 0.0032 0.0167 0.0274
Mycobacterium ulcerans hypothetical protein 0.0024 0.0069 0.0192
Brugia malayi putative neuropeptide receptor 0.0038 0.0235 0.0358
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0092 0.0887 1
Entamoeba histolytica hypothetical protein 0.0021 0.0037 0.0129
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0068 0.0068
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0235 0.0255
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0056 0.0451 0.0451
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0027 0.0102 0.0255
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0089 0.0844 0.1284
Loa Loa (eye worm) pyruvate kinase-PB 0.0048 0.0354 0.0538
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0255 0.0276
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0235 0.0255
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0243 0.2696 0.2918
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0081 0.0755 0.0817
Schistosoma mansoni hypothetical protein 0.0049 0.0374 0.0404
Echinococcus multilocularis cation transporting ATPase 13A1 0.0022 0.004 0.004
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0424 0.2923
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0022 0.004 0.0069
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0205 0.1623
Leishmania major cathepsin L-like protease 0.0035 0.0205 0.1334
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0146 0.0221
Echinococcus granulosus tumor protein p63 0.0355 0.404 0.6605
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0034 0.0188 0.0287
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0235 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0149 0.0462
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0217 0.0801
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0069 0.0192
Schistosoma mansoni type V p-type atpase isoform 0.0022 0.004 0.0043
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0022 0.004 0.0064
Leishmania major p-glycoprotein e 0.004 0.0265 0.1764
Brugia malayi RNA binding protein 0.0067 0.0591 0.0899
Schistosoma mansoni amine GPCR 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0235 0.0255
Echinococcus multilocularis multidrug resistance associated protein 1 0.004 0.0265 0.0265
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0039 0.0255 0.0276
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0348 0.2884
Brugia malayi Serotonin receptor 0.0038 0.0235 0.0358
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Loa Loa (eye worm) RNA binding protein 0.0067 0.0591 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Brugia malayi AKH receptor 0.0038 0.0235 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Plasmodium vivax SET domain protein, putative 0.0032 0.0166 0.1662
Echinococcus granulosus multidrug resistance associated protein 7 0.004 0.0265 0.0433
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0235 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0243 0.2696 0.4409
Trichomonas vaginalis pyruvate kinase, putative 0.0068 0.0602 0.2106
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0107 0.0621
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0243 0.2696 0.4101
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.004 0.0263 0.0923
Leishmania major copper-transporting ATPase-like protein, putative 0.0022 0.004 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0111 0.0169
Echinococcus granulosus dnaJ subfamily B 0.0433 0.4979 0.8141
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0235 0.0255
Trypanosoma brucei multidrug resistance-associated protein, putative 0.004 0.0265 0.1795
Leishmania major pyruvate kinase 0.0068 0.0602 0.4218
Brugia malayi Pre-SET motif family protein 0.0032 0.0166 0.0252
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0021 0.0037 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0348 0.1184
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0591 0.064
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0424 0.0693
Echinococcus granulosus pyruvate kinase 0.0035 0.0203 0.0331
Echinococcus granulosus pyruvate kinase 0.0068 0.0602 0.0984
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0056 0.0451 0.3145
Loa Loa (eye worm) beta-lactamase 0.0037 0.0221 0.0337
Echinococcus multilocularis dna polymerase eta 0.002 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0221 0.145
Entamoeba histolytica hypothetical protein 0.0025 0.0081 0.0518
Loa Loa (eye worm) hypothetical protein 0.0053 0.042 0.0638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0232 0.0763
Brugia malayi nuclear hormone receptor 0.0115 0.1156 0.1759
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0243 0.2696 0.2696
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0173 0.1097
Echinococcus granulosus copper transporting ATPase 1 0.0022 0.004 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0166 0.0179
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0348 0.24
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0235 0.0358
Loa Loa (eye worm) GABA receptor subunit 0.0021 0.0037 0.0056
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0235 0.0358
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0022 0.004 0.0043
Trichomonas vaginalis esterase, putative 0.0037 0.0221 0.0724
Mycobacterium tuberculosis Conserved protein 0.0037 0.0221 0.0776
Echinococcus multilocularis somatostatin receptor 0.0038 0.0235 0.0235
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0032 0.017 0.017
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0243 0.2696 0.4101
Trichomonas vaginalis ABC transporter, half transporter, putative 0.004 0.0263 0.0877
Loa Loa (eye worm) serotonin transporter b 0.019 0.2067 0.3144
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0069 0.0192
Onchocerca volvulus 0.0035 0.0205 0.074
Brugia malayi Uncoordinated protein 44 0.003 0.0146 0.0221
Brugia malayi Sodium:neurotransmitter symporter family protein 0.019 0.2067 0.3144
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Brugia malayi excitatory GABA receptor EXP-1A 0.0039 0.0255 0.0388
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0424 0.2923
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0235 0.0385
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0056 0.0451 0.0488
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0039 0.0255 0.0417
Echinococcus granulosus cathepsin l1 0.0035 0.0205 0.0336
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0166 0.0179
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Trypanosoma brucei pyruvate kinase 1 0.0068 0.0602 0.424
Echinococcus granulosus aryl hydrocarbon receptor 0.0027 0.0102 0.0166
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0243 0.2696 0.4409
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Loa Loa (eye worm) hypothetical protein 0.0068 0.0602 0.0915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0172 0.0583
Mycobacterium tuberculosis Conserved protein 0.0037 0.0221 0.0776
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0235 0.0235
Brugia malayi ABC transporter transmembrane region family protein 0.004 0.0265 0.0402
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0149 0.0161
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Schistosoma mansoni hypothetical protein 0.0433 0.4979 0.5388
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Entamoeba histolytica P-glycoprotein-5 0.004 0.0263 0.2136
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0235 0.0235
Echinococcus granulosus FTZ F1 alpha 0.0243 0.2696 0.4409
Leishmania major cathepsin L-like protease 0.0035 0.0205 0.1334
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Giardia lamblia Multidrug resistance-associated protein 1 0.004 0.0265 0.2326
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0115 0.1156 0.1156
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0038 0.0242 0.195
Loa Loa (eye worm) hypothetical protein 0.0473 0.5453 0.8293
Trypanosoma brucei P-type H+-ATPase, putative 0.0043 0.0302 0.2068
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.017 0.0184
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0068 0.06 0.4224
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0235 0.0235
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.004 0.0263 0.0877
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0235 0.0235
Schistosoma mansoni hypothetical protein 0.0114 0.1152 0.1247
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0348 0.0377
Trypanosoma cruzi pyruvate kinase 2, putative 0.0068 0.0602 0.4218
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.004 0.0263 0.1756
Onchocerca volvulus 0.0038 0.0235 0.0847
Echinococcus multilocularis multidrug resistance protein 1 0.004 0.0263 0.0263
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0079 0.0724 0.1101
Loa Loa (eye worm) ACC-1 protein 0.0039 0.0255 0.0388
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0039 0.0255 0.0388
Onchocerca volvulus 0.0038 0.0235 0.0847
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0356
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0022 0.004 0.0129
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0602 0.0915
Onchocerca volvulus 0.0035 0.0205 0.074
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0755 0.5335
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0173 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0243 0.2696 0.4101
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0068 0.06 0.4224
Plasmodium vivax pyruvate kinase, putative 0.0068 0.0602 0.67
Loa Loa (eye worm) CYP4Cod1 0.002 0.0026 0.0039
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0128 0.1321 0.201
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Schistosoma mansoni multidrug resistance protein 0.004 0.0263 0.0285
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) fibroinase 0.0035 0.0205 0.0312
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0217 0.071
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0081 0.0755 0.7032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0032 0.017 0.0184
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Entamoeba histolytica ABC transporter, putative 0.004 0.0265 0.2145
Loa Loa (eye worm) glutathione reductase 0.005 0.0378 0.0574
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Entamoeba histolytica pyruvate kinase, putative 0.0048 0.0354 0.2934
Loa Loa (eye worm) hypothetical protein 0.0151 0.1591 0.242
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.019 0.2067 0.2237
Brugia malayi Cathepsin L-like precursor 0.0035 0.0205 0.0312
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0119 0.1213 0.4881
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0424 0.0693
Onchocerca volvulus 0.0039 0.0255 0.0918
Loa Loa (eye worm) DR-78 0.0115 0.1156 0.1759
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0243 0.2696 0.2918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0236
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0102 0.0579
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0374 0.0568
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0424 0.0645
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0068 0.06 0.4202
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0235 0.0235
Trypanosoma cruzi cation-transporting ATPase, putative 0.0022 0.004 0.0129
Onchocerca volvulus 0.0038 0.0235 0.0847
Mycobacterium ulcerans putative regulatory protein 0.0076 0.0693 0.2748
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0243 0.2696 0.4101
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Brugia malayi isocitrate dehydrogenase 0.0033 0.0173 0.0263
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0081 0.0228
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0065 0.0383
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0243 0.2696 0.4101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus granulosus g protein coupled receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.004 0.0263 0.0401
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0337
Brugia malayi G protein-coupled receptor 0.0038 0.0235 0.0358
Brugia malayi hypoxia-induced factor 1 0.0318 0.3592 0.5463
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.004 0.0263 0.279
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0115 0.1156 0.1252
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0115 0.1156 0.1759
Brugia malayi sulfakinin receptor protein 0.0038 0.0235 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0243 0.2696 0.4101
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.1152 0.1152
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0107 0.0621
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0069 0.0341
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0081 0.0426
Loa Loa (eye worm) hypothetical protein 0.0051 0.0396 0.0602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0069 0.0192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0243 0.2696 0.9706
Brugia malayi hypothetical protein 0.0115 0.1156 0.1759
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0235 0.0255
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0022 0.004 0.0166
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0056 0.0451 0.1557
Echinococcus multilocularis ecdysone induced protein 78C 0.0243 0.2696 0.2696
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0487 0.5373
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus granulosus cathepsin l1 0.0024 0.0065 0.0107
Brugia malayi neuropeptide F receptor 0.0038 0.0235 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Onchocerca volvulus 0.0038 0.0235 0.0847
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0056 0.0451 0.3119
Echinococcus multilocularis neuropeptide receptor A26 0.0528 0.6116 0.6116
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0065 0.0071
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0205 0.0336
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Onchocerca volvulus 0.0032 0.017 0.0611
Plasmodium vivax cation transporting ATPase, putative 0.0022 0.004 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Leishmania major cathepsin L-like protease 0.0135 0.1396 1
Echinococcus multilocularis muscleblind protein 0.0151 0.1591 0.1591
Brugia malayi intermediate filament protein 0.0057 0.0464 0.0706
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0115 0.1156 0.1891
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0039 0.0255 0.0388
Schistosoma mansoni hypothetical protein 0.0049 0.0374 0.0404
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0873 0.309
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0378 0.0617
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0243 0.2696 0.2696
Loa Loa (eye worm) hypothetical protein 0.0243 0.2696 0.4101
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.1705
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0022 0.0034
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0173 0.0173
Brugia malayi nuclear hormone receptor family member odr-7 0.0115 0.1156 0.1759
Onchocerca volvulus 0.0037 0.0221 0.0797
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0235 0.0235
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0235 0.0385
Trypanosoma cruzi P-type H+-ATPase, putative 0.0043 0.0302 0.2038
Leishmania major DNA polymerase eta, putative 0.002 0.0025 0.0022
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0235 0.0358
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0221 0.0724
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0235 0.0385
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0243 0.2696 0.2918
Echinococcus multilocularis serotonin transporter 0.019 0.2067 0.2067
Entamoeba histolytica multidrug resistance protein, putative 0.004 0.0265 0.2145
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0173 0.1742
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0591 0.0899
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0217 0.1454
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0056 0.0451 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Brugia malayi Dopamine receptor protein 2 0.0038 0.0235 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Brugia malayi Cation transporter family protein 0.0039 0.0255 0.0388
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0022 0.004 0.0065
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0063 0.0103
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0026 0.0028
Onchocerca volvulus 0.0021 0.0037 0.0132
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Echinococcus granulosus pyruvate kinase 0.0035 0.0203 0.0331
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.2098
Echinococcus granulosus sodium and chloride dependent glycine 0.0032 0.017 0.0277
Echinococcus multilocularis FTZ F1 alpha 0.0243 0.2696 0.2696
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0057 0.0462 0.0702
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0205 0.212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus 0.0038 0.0235 0.0847
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0591 0.0899
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0235 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0348 0.1184
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0243 0.2696 0.2696
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0591 0.064
Entamoeba histolytica ATP-binding cassette protein, putative 0.004 0.0265 0.2145
Loa Loa (eye worm) hypothetical protein 0.0566 0.6575 1
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0079 0.0724 0.0783
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Plasmodium falciparum glutathione reductase 0.005 0.0378 0.4109
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0233 0.1532
Schistosoma mansoni netrin receptor unc5 0.003 0.0146 0.0157
Loa Loa (eye worm) E1-E2 ATPase 0.0043 0.0302 0.0459
Echinococcus granulosus sex peptide receptor 0.0038 0.0235 0.0385
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0243 0.2696 0.4101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0022 0.004 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0243 0.2696 0.4101
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0107 0.1065 0.1152
Schistosoma mansoni opsin-like receptor 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0235 0.0255
Schistosoma mansoni sodium-dependent amino acid transporter 0.0032 0.017 0.0184
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Loa Loa (eye worm) hypothetical protein 0.0035 0.0205 0.0312
Onchocerca volvulus 0.0039 0.0255 0.0918
Onchocerca volvulus 0.0038 0.0235 0.0847
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0039 0.0255 0.0255
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0255 0.0276
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0056
Trichomonas vaginalis ABC transporter, putative 0.004 0.0263 0.0877
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0424 0.295
Brugia malayi beta-lactamase 0.0037 0.0221 0.0337
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0039 0.0255 0.0388
Echinococcus multilocularis tumor protein p63 0.0355 0.404 0.404
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0032 0.017 0.0277
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0378 0.4109
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0067
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0022 0.004 0.0157
Echinococcus multilocularis glycine receptor subunit beta 0.0039 0.0255 0.0255
Brugia malayi ORL1-like opioid receptor 0.0038 0.0235 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0172 0.0542
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0173 0.1097
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0092 0.0887 0.0887
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0128 0.1321 0.1321
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0115 0.1156 0.1156
Echinococcus granulosus cation transporting ATPase 13A3 0.0022 0.004 0.0065
Echinococcus granulosus serotonin transporter 0.019 0.2067 0.338
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0079 0.0724 0.0783
Leishmania major hypothetical protein, conserved 0.0053 0.042 0.2893
Brugia malayi Dopamine receptor protein 1 0.0038 0.0235 0.0358
Brugia malayi Membrane calcium atpase protein 3 0.0056 0.0451 0.0686
Brugia malayi MH2 domain containing protein 0.0253 0.2812 0.4277
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0173 0.0173
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0032 0.017 0.017
Onchocerca volvulus 0.0039 0.0255 0.0918
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0022 0.004 0.0073
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus 0.0024 0.0069 0.0248
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.004 0.0263 0.0431
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0025 0.0038
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0081 0.0676
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0223 0.2463 1
Echinococcus multilocularis copper transporting ATPase 1 0.0022 0.004 0.004
Echinococcus granulosus nAChR subunit 0.0021 0.0037 0.006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.511
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.1705
Mycobacterium tuberculosis Probable reductase 0.0113 0.1141 0.4357
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0235 0.0385
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0115 0.1156 0.1891
Mycobacterium ulcerans pyruvate kinase 0.0068 0.0602 0.2375
Entamoeba histolytica hypothetical protein 0.0114 0.1152 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0039 0.0255 0.0388
Schistosoma mansoni sodium/chloride dependent transporter 0.019 0.2067 0.2237
Brugia malayi nuclear receptor RXR 0.0128 0.1321 0.201
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0205 0.1623
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0223 0.2463 1
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0102 0.0579
Entamoeba histolytica ATP-binding cassette protein, putative 0.004 0.0265 0.2145
Trypanosoma cruzi multidrug resistance protein E, putative 0.004 0.0265 0.1764
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0337
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.042 0.4595
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0235 0.0235
Leishmania major hypothetical protein, conserved 0.0037 0.0221 0.145
Echinococcus granulosus intermediate filament protein 0.0057 0.0464 0.0759
Brugia malayi hypothetical protein 0.0159 0.1686 0.2564
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0022
Echinococcus granulosus death domain containing protein 0.003 0.0146 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0424 0.1459
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0255 0.0388
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.017 0.0184
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0173 0.1742
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0844 0.0914
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.004 0.0256 0.0419
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0022 0.004 0.0205
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0146 0.0221
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0037 0.0056
Loa Loa (eye worm) hypothetical protein 0.0073 0.0654 0.0994
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Echinococcus granulosus dna polymerase eta 0.002 0.0025 0.0041
Echinococcus multilocularis cysteine protease 0.0035 0.0205 0.0205
Echinococcus multilocularis calcium transporting atpase 0.0079 0.0724 0.0724
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0235 0.0358
Brugia malayi nuclear receptor RXR 0.0115 0.1156 0.1759
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0378 0.2587
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.1293 0.4947
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0591 0.0591
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0217 0.1729
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0022 0.004 0.0069
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0235 0.0358
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0235 0.0235
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0235 0.0255
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0039 0.0255 0.0255
Schistosoma mansoni amine GPCR 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0027 0.0102 0.0155
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Onchocerca volvulus 0.0089 0.0844 0.304
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.511
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0205 0.212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0235 0.0255
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0243 0.2696 0.2918
Echinococcus multilocularis pyruvate kinase 0.0035 0.0203 0.0203
Echinococcus granulosus nuclear receptor nhr 48 0.0115 0.1156 0.1891
Echinococcus multilocularis netrin receptor unc 5 0.003 0.0146 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.004 0.0263 0.279
Brugia malayi Serotonin receptor 0.0038 0.0235 0.0358
Echinococcus granulosus allatostatin A receptor 0.0038 0.0235 0.0385
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Echinococcus multilocularis GPCR, family 2 0.0049 0.0374 0.0374
Mycobacterium ulcerans beta-lactamase 0.0037 0.0221 0.0816
Onchocerca volvulus 0.0038 0.0235 0.0847
Giardia lamblia DINP protein human, muc B family 0.002 0.0025 0.003
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0235 0.0358
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus Bile acid receptor homolog 0.0243 0.2696 0.9706
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0337
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0102 0.0289
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0156 0.1653 0.2514
Onchocerca volvulus 0.0057 0.0464 0.1671
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0235 0.0235
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0032 0.017 0.0277
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0065 0.0157
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0235 0.0385
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0235 0.0847
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0025 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Schistosoma mansoni hypothetical protein 0.0522 0.6045 0.6542
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0046 0.0337 0.1227
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0025 0.0041
Schistosoma mansoni cpg binding protein 0.003 0.0147 0.0159
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0424 0.0424
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0037 0.0056
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0755 0.1235
Leishmania major protein kinase, putative 0.0027 0.0107 0.0621
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0464 0.0706
Mycobacterium ulcerans hypothetical protein 0.0037 0.0221 0.0816
Loa Loa (eye worm) hypothetical protein 0.0128 0.1321 0.201
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0755 0.5335
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus 0.0032 0.017 0.0611
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0243 0.2696 0.4101
Echinococcus granulosus Nuclear hormone receptor HR96 0.0115 0.1156 0.1891
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0243 0.2696 0.4101
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0173 0.0187
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0205 0.0205
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0022 0.004 0.0069
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0235 0.0385
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0107 0.1061 0.1614
Schistosoma mansoni hypothetical protein 0.0038 0.0235 0.0255
Echinococcus multilocularis serotonin receptor 0.0038 0.0235 0.0235
Echinococcus multilocularis sex peptide receptor 0.0038 0.0235 0.0235
Schistosoma mansoni hypothetical protein 0.0038 0.0235 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0243 0.2696 0.4101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0356
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0255 0.0388
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.004 0.0257 0.0391
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0235 0.0235
Schistosoma mansoni single-minded 0.0103 0.1013 0.1096
Entamoeba histolytica P-glycoprotein-2 0.004 0.0263 0.2136
Brugia malayi E1-E2 ATPase family protein 0.0045 0.0317 0.0482
Toxoplasma gondii pyruvate kinase PyK1 0.0068 0.0602 0.67
Plasmodium vivax vivapain-2 0.0035 0.0205 0.212
Schistosoma mansoni nuclear hormone receptor 0.0243 0.2696 0.2918
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0173 0.1742
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Brugia malayi nuclear hormone receptor 0.0243 0.2696 0.4101
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.004 0.0263 0.0877
Echinococcus granulosus neuropeptide receptor A26 0.0528 0.6116 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0069 0.0414
Schistosoma mansoni nuclear hormone receptor 0.0115 0.1156 0.1252
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0027 0.0102 0.0155
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0602 0.0915
Schistosoma mansoni amine GPCR 0.0038 0.0235 0.0255
Trypanosoma brucei multidrug resistance-associated protein, putative 0.004 0.0265 0.1795
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0221 0.2303
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0844 0.0844
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.003 0.0139 0.0211
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0039 0.0255 0.0417
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.1141 0.4357
Brugia malayi larval opioid receptor 0.0038 0.0235 0.0358
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0217 0.1422
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0111 0.0182
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.017 0.0184
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.004 0.0263 0.0431
Brugia malayi Thioredoxin reductase 0.005 0.0378 0.0574
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0034 0.0188 0.1211
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0081 0.0676
Plasmodium vivax copper-transporting ATPase, putative 0.0022 0.004 0.0205
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0069 0.0614 0.5239
Brugia malayi Death domain containing protein 0.003 0.0146 0.0221
Onchocerca volvulus 0.0038 0.0235 0.0847
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0065 0.0157
Echinococcus multilocularis cation transporting ATPase 13A3 0.0022 0.004 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0235 0.0255
Onchocerca volvulus Netrin receptor homolog 0.003 0.0146 0.0524
Leishmania major P-type ATPase, putative 0.0056 0.0451 0.3119
Loa Loa (eye worm) hypothetical protein 0.0344 0.3912 0.595
Onchocerca volvulus 0.0119 0.1213 0.4368
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0235 0.0255
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0025 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0289 0.1039
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0068 0.06 0.4202
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0022 0.004 0.0073
Trichomonas vaginalis abcb9, putative 0.004 0.0263 0.0877
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1396 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0255 0.0388
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0205 0.0205
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0045 0.0317 0.0482
Schistosoma mansoni nuclear receptor 0.0115 0.1156 0.1252
Entamoeba histolytica ATP-binding cassette protein, putative 0.004 0.0265 0.2145
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0147 0.0223
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0027 0.0102 0.0289
Schistosoma mansoni intermediate filament proteins 0.0057 0.0464 0.0502
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0205 0.074
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0032 0.017 0.0277
Onchocerca volvulus 0.0039 0.0255 0.0918
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0233 0.1564
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0032 0.017 0.017
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0221 0.145
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.003 0.0139 0.0211
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.1061 0.1614
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0166 0.0179
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0173 0.0173
Brugia malayi G-protein coupled receptor 0.0038 0.0235 0.0358
Schistosoma mansoni multidrug resistance protein 0.004 0.0263 0.0285
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0217 0.0356
Schistosoma mansoni neuropeptide receptor 0.0038 0.0235 0.0255
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0235 0.0235
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0166 0.0179
Schistosoma mansoni ap endonuclease 0.002 0.0022 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0187 0.2029 0.2029
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0056 0.0451 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0235 0.0358
Schistosoma mansoni neurotransmitter gated ion channel 0.0021 0.0037 0.004
Toxoplasma gondii cathepsin CPL 0.0035 0.0205 0.212
Onchocerca volvulus 0.0038 0.0235 0.0847
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0032 0.017 0.0277
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.004 0.0263 0.0877
Leishmania major calcium-translocating P-type ATPase 0.0091 0.0873 0.619
Loa Loa (eye worm) hypothetical protein 0.0115 0.1156 0.1759
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0235 0.0255
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0069 0.0119
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0235 0.0385
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Toxoplasma gondii thioredoxin reductase 0.005 0.0378 0.4109
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0173 0.1742
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0591 0.064
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0081 0.024
Schistosoma mansoni hypothetical protein 0.003 0.0146 0.0157
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0081 0.0168
Trichomonas vaginalis adenylate cyclase, putative 0.0027 0.0102 0.0289
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0235 0.0385
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1396 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0348 0.2372
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Leishmania major DNA polymerase kappa, putative 0.002 0.0025 0.0022
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0107 0.1065 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0069 0.0119
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0235 0.0235
Echinococcus granulosus multidrug resistance protein 1 0.004 0.0263 0.0431
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.003 0.0045
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0069 0.0614 0.0614
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.2098
Schistosoma mansoni opsin-like receptor 0.0038 0.0235 0.0255
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0115 0.1156 0.1759
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0025 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0238
Brugia malayi calcium ATPase 0.003 0.0139 0.0211
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0221 0.0776
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0128 0.1321 0.201
Entamoeba histolytica hypothetical protein 0.004 0.0265 0.2145
Giardia lamblia Copper-transporting P-type ATPase 0.0022 0.004 0.017
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.003 0.0139 0.0849
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0602 0.2166
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0235 0.0385
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.006
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0205 0.0222
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0046 0.0337 0.1291
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0374 0.0611
Brugia malayi Steroid receptor seven-up type 2 0.0243 0.2696 0.4101
Leishmania major p-glycoprotein 0.004 0.0263 0.1756
Trypanosoma brucei calcium-transporting ATPase, putative 0.0034 0.0188 0.1244
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Schistosoma mansoni histamine h1 receptor 0.0038 0.0235 0.0255
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Echinococcus multilocularis Ankyrin 0.0031 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0156 0.1653 0.2514
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0243 0.2696 0.4101
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0115 0.1156 0.4163
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0374 0.0568
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.004 0.0263 0.0263
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0205 0.0336
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0235 0.0358
Plasmodium vivax vivapain-2 0.0035 0.0205 0.212
Echinococcus granulosus lamin 0.0057 0.0464 0.0759
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0205 0.0205
Leishmania major calcium motive p-type ATPase, putative 0.0056 0.0451 0.3119
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0235 0.0255
Brugia malayi Nuclear hormone receptor-like 1 0.0128 0.1321 0.201
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0374 0.0568
Brugia malayi Muscleblind-like protein 0.0151 0.1591 0.242
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0025 0.0013
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.004 0.0263 0.0263
Echinococcus multilocularis ATP binding cassette sub family B 0.004 0.0256 0.0256
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0602 0.0915
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0424 0.2923
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0069 0.0192
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0069 0.0182
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Brugia malayi steroid hormone receptor 0.0243 0.2696 0.4101
Onchocerca volvulus 0.0038 0.0235 0.0847
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0235 0.0235
Echinococcus multilocularis multidrug resistance protein 1 0.004 0.0263 0.0263
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0348 0.2372
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0173 0.0263
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0235 0.0385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0205 0.0666
Onchocerca volvulus 0.0038 0.0235 0.0847
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0235 0.0235
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0173 0.0587
Schistosoma mansoni cation-transporting atpase worm 0.0022 0.004 0.0043
Leishmania major cathepsin L-like protease 0.0035 0.0205 0.1334
Schistosoma mansoni nAChR subunit 0.0039 0.0255 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0102 0.0289
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0068 0.06 0.2098
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0348 0.2884
Echinococcus granulosus neuropeptide s receptor 0.0528 0.6116 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0069 0.0105
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0147 0.0224
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.1293 0.5141
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0128 0.1321 0.143
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1396 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0069 0.0414
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0255 0.0388
Loa Loa (eye worm) hypothetical protein 0.0038 0.0235 0.0358
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0205 0.074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0221 0.0337
Brugia malayi Cathepsin L-like precursor 0.0035 0.0205 0.0312
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0039 0.0255 0.0417
Brugia malayi ecdysteroid receptor 0.0243 0.2696 0.4101
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0068 0.06 0.4224
Loa Loa (eye worm) hypothetical protein 0.0076 0.0693 0.1054
Loa Loa (eye worm) steroid hormone receptor 0.0243 0.2696 0.4101
Brugia malayi beta-lactamase family protein 0.0037 0.0221 0.0337
Loa Loa (eye worm) hypothetical protein 0.019 0.2067 0.3144
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0844 0.1381
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.0258
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0755 0.0755
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0022 0.0022
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0039 0.0255 0.0255
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0022 0.004 0.0073
Brugia malayi Pre-SET motif family protein 0.0219 0.2412 0.3669
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0243 0.2696 0.2696
Schistosoma mansoni cpg binding protein 0.0032 0.0167 0.0181
Plasmodium vivax P-type ATPase4, putative 0.0092 0.0887 1
Toxoplasma gondii hypothetical protein 0.0032 0.017 0.1705
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0221 0.0776
Mycobacterium tuberculosis Conserved protein 0.0037 0.0221 0.0776
Echinococcus multilocularis muscleblind protein 1 0.0151 0.1591 0.1591
Echinococcus granulosus neuropeptide receptor 0.0038 0.0235 0.0385
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0235 0.0385
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0022 0.004 0.0064
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0232 0.0763
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0265 0.0883
Schistosoma mansoni inositol monophosphatase 0.0036 0.0217 0.0235
Echinococcus multilocularis multidrug resistance associated protein 4 0.0023 0.0057 0.0057
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0315 0.3559 0.3559
Schistosoma mansoni sodium/chloride dependent transporter 0.0033 0.0175 0.019
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0755 0.1235
Entamoeba histolytica cysteine protease, putative 0.0035 0.0205 0.1623
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0235 0.0385
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0069 0.0182
Brugia malayi nuclear receptor NHR-67 0.0115 0.1156 0.1759
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0156 0.1653 0.2514
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0235 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0424 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0205 0.0666
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0187 0.2029 0.3086
Treponema pallidum DNA polymerase III subunit alpha 0.0223 0.2463 1
Schistosoma mansoni biogenic amine receptor 0.0038 0.0235 0.0255
Giardia lamblia Pyruvate kinase 0.0068 0.0602 0.556
Onchocerca volvulus 0.0115 0.1156 0.4163
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.004 0.0265 0.1764
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0039 0.0255 0.0255
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0022 0.0036
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.004 0.0263 0.0877
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0235 0.0235
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0039 0.0255 0.0388
Plasmodium vivax glutathione reductase, putative 0.005 0.0378 0.4109
Onchocerca volvulus 0.0038 0.0235 0.0847
Leishmania major P-type H -ATPase, putative 0.0043 0.0302 0.2038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0069 0.0192
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0121 0.1228 0.1867
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.003 0.0139 0.0849
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0057 0.0462 0.0702
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.042 0.292
Trypanosoma brucei protein kinase, putative 0.0054 0.0424 0.295
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0217 0.1422
Echinococcus granulosus multidrug resistance protein 1 0.004 0.0263 0.0431
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0388
Schistosoma mansoni nuclear receptor nhr-48 0.0115 0.1156 0.1252
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0235 0.0385
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0221 0.0724
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.0258
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0235 0.0358
Plasmodium vivax hypothetical protein, conserved 0.0032 0.017 0.1705
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.1152 0.1247
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0146 0.0146
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0081 0.0462
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0133 0.1381 0.1381
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0026 0.0016
Brugia malayi hypothetical protein 0.0038 0.0235 0.0358
Leishmania major cathepsin L-like protease 0.0035 0.0205 0.1334
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0217 0.2259
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.017 0.1705
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0055 0.0436 0.3973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0348 0.1184
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0069 0.0105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0374 0.0611
Echinococcus granulosus dna polymerase kappa 0.002 0.0025 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0203 0.0657
Onchocerca volvulus 0.004 0.0263 0.0948
Echinococcus granulosus multidrug resistance associated protein 4 0.0023 0.0057 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0235 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0236
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0039 0.0255 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0087 0.0236
Treponema pallidum cation-transporting ATPase, P-type 0.0022 0.004 0.0073
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0091 0.0873 0.1427
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0102 0.0579
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0235 0.0235
Trypanosoma cruzi P-type H+-ATPase, putative 0.003 0.0139 0.0849
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0128 0.1321 0.201
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0025 0.006
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.005 0.0236
Echinococcus multilocularis glycine receptor subunit beta 0.0039 0.0255 0.0255
Brugia malayi Protein kinase domain containing protein 0.0031 0.0151 0.023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0065 0.0099

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 89 % Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding assay relative to control ChEMBL. 20036561
EC50 (functional) = 7.6 nM Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding assay ChEMBL. 20036561
IC50 (binding) = 72.6 nM Mitogenesis inhibition method BINDINGDB. No reference
Ki (binding) = 0.51 uM Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells ChEMBL. 20036561
Ki (binding) = 27.1 uM Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs ChEMBL. 20036561

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.