Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0052 | 0.0255 | 0.0887 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0047 | 0.0219 | 0.0764 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0015 | 0.0024 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0013 | 0.0046 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0058 | 0.0203 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0166 | 0.0738 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.0189 | 0.0373 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0103 | 0.036 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0103 | 0.0103 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0103 | 0.0103 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.044 | 0.0866 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0235 | 0.0818 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0166 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0058 | 0.029 |
Loa Loa (eye worm) | acetyltransferase | 0.0151 | 0.0856 | 0.2982 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0329 | 0.1944 | 0.1944 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0291 | 0.1713 | 1 |
Mycobacterium ulcerans | putative regulatory protein | 0.0038 | 0.0166 | 0.0201 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0018 | 0.0047 | 0.0026 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0058 | 0.0115 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0166 | 0.0738 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0058 | 0.0115 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Loa Loa (eye worm) | PDE1B protein | 0.0015 | 0.0024 | 0.0083 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0032 | 0.0133 | 0.0133 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0065 | 0.0127 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0065 | 0.0062 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0076 | 0.0149 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.0381 | 0.075 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0058 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0166 | 0.0309 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0255 | 0.1202 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0015 | 0.0024 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0364 | 0.1268 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0464 | 0.2776 | 0.5463 |
Brugia malayi | Uncoordinated protein 44 | 0.0032 | 0.0133 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0133 | 0.0462 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0065 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0009 | 0.0017 |
Brugia malayi | protein C24B5.3 | 0.0012 | 0.0009 | 0.0017 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0381 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0058 | 0.0115 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0058 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.044 | 0.0866 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0058 | 0.0115 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0021 | 0.0065 | 0.0062 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0285 | 0.1681 | 0.1681 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1157 | 0.4031 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0015 | 0.0024 | 0.0047 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0058 | 0.0203 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0247 | 0.0424 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0072 | 0.0377 | 0.0623 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0021 | 0.0065 | 0.011 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0166 | 0.0326 |
Toxoplasma gondii | GAF domain-containing protein | 0.0038 | 0.0166 | 0.0309 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0032 | 0.0133 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.1713 | 0.597 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0015 | 0.0024 | 0.0083 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0103 | 0.036 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0058 | 0.0203 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0247 | 0.0424 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0072 | 0.0377 | 0.0623 |
Echinococcus granulosus | death domain containing protein | 0.0032 | 0.0133 | 0.0462 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0021 | 0.0065 | 0.0127 |
Leishmania major | dihydroorotate dehydrogenase | 0.0841 | 0.5082 | 1 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0841 | 0.5082 | 1 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Brugia malayi | Patched related family protein 4 | 0.0012 | 0.0009 | 0.0017 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.0081 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0025 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0204 | 0.0711 |
Mycobacterium ulcerans | putative regulatory protein | 0.0038 | 0.0166 | 0.0201 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0144 | 0.0816 | 0.2844 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0072 | 0.0377 | 0.0681 |
Echinococcus multilocularis | expressed conserved protein | 0.0188 | 0.1083 | 0.1083 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.0319 | 0.1112 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0021 | 0.0065 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0021 | 0.0065 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0058 | 0.0115 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0219 | 0.0432 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0072 | 0.0377 | 0.0623 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0072 | 0.0377 | 0.0623 |
Brugia malayi | Patched related family protein 12 | 0.0012 | 0.0009 | 0.0017 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0153 | 0.0153 |
Onchocerca volvulus | 0.0028 | 0.0103 | 0.0555 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0047 | 0.0219 | 0.0219 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0065 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0216 | 0.0752 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0065 | 0.0127 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0021 | 0.0065 | 0.0062 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0131 | 0.0455 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0034 | 0.0049 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0034 | 0.0019 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0015 | 0.0024 | 0.0083 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0076 | 0.0264 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0032 | 0.0133 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.006 | 0.0209 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Schistosoma mansoni | netrin receptor unc5 | 0.0032 | 0.0133 | 0.0261 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0377 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0058 | 0.0203 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0058 | 0.0115 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0166 | 0.0281 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0054 | 0.0265 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.02 | 0.1157 | 0.2276 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0329 | 0.1944 | 0.3826 |
Loa Loa (eye worm) | patched family protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0265 | 0.0925 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0052 | 0.0255 | 0.0255 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0038 | 0.0075 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0203 | 0.1176 | 0.2314 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.0554 | 0.1089 |
Brugia malayi | Patched protein homolog 1 | 0.0012 | 0.0009 | 0.0017 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0058 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.2687 | 0.9362 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0065 | 0.0081 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0168 | 0.0584 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Plasmodium falciparum | phosphodiesterase gamma, putative | 0.0015 | 0.0024 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0265 | 0.0925 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0028 | 0.0007 |
Brugia malayi | protein C24B5.3 | 0.0012 | 0.0009 | 0.0017 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0291 | 0.1713 | 1 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0052 | 0.0255 | 0.0456 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Onchocerca volvulus | Netrin receptor homolog | 0.0032 | 0.0133 | 0.0726 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0015 | 0.0024 | 0.003 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0117 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0038 | 0.0075 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0131 | 0.0257 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.0216 | 0.0408 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.1198 | 0.4173 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0841 | 0.5082 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0072 | 0.0377 | 0.0699 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0021 | 0.0064 | 0.0224 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.0038 | 0.0166 | 0.0261 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0009 | 0.0017 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0021 | 0.0065 | 0.0062 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0049 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0058 | 0.0058 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0032 | 0.0133 | 0.0261 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0131 | 0.0455 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0015 | 0.0024 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.1713 | 0.597 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.048 | 0.287 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0032 | 0.0133 | 0.0133 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0065 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0058 | 0.0115 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0377 | 0.1315 |
Brugia malayi | CHE-14 protein | 0.0086 | 0.0459 | 0.0904 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0116 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0381 | 0.1684 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.0381 | 0.0381 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0058 | 0.0203 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0131 | 0.0257 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0021 | 0.0065 | 0.011 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0098 | 0.0533 | 0.105 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0151 | 0.0856 | 0.0856 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0072 | 0.0377 | 0.1663 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0009 | 0.0017 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0058 | 0.0115 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0117 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0021 | 0.0065 | 0.0225 |
Plasmodium falciparum | phosphodiesterase delta, putative | 0.0015 | 0.0024 | 0.003 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.01 | 0.035 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0131 | 0.0257 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0024 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0065 | 0.0062 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0021 | 0.0065 | 0.0065 |
Plasmodium vivax | phosphodiesterase gamma, putative | 0.0015 | 0.0024 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0142 | 0.0153 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0052 | 0.0255 | 0.0456 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0054 | 0.0265 | 0.0506 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0058 | 0.0058 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0024 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0103 | 0.0204 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0065 | 0.0213 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0072 | 0.0377 | 0.0699 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0058 | 0.0115 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0058 | 0.0058 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0058 | 0.0058 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0072 | 0.0377 | 0.0623 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0058 | 0.0115 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.0699 | 0.2434 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0072 | 0.0377 | 0.0623 |
Loa Loa (eye worm) | oxidoreductase | 0.0021 | 0.0065 | 0.0225 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Loa Loa (eye worm) | patched family protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0131 | 0.0455 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0131 | 0.0257 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0058 | 0.0115 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0142 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0058 | 0.0203 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0065 | 0.0081 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0038 | 0.0166 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0065 | 0.0127 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0058 | 0.0115 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0358 | 0.0704 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0058 | 0.0115 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0058 | 0.0203 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0151 | 0.0856 | 0.1684 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0166 | 0.0538 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0028 | 0.0054 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0381 | 0.1684 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0219 | 0.0432 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0058 | 0.0058 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0058 | 0.0203 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0034 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0285 | 0.1681 | 0.5858 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0377 | 0.1315 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0058 | 0.0115 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0841 | 0.5082 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0034 | 0.0019 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0015 | 0.0024 | 0.0083 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0841 | 0.5082 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0034 | 0.0049 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0116 | 0.0228 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0841 | 0.5082 | 1 |
Brugia malayi | hypothetical protein | 0.048 | 0.287 | 0.5648 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0038 | 0.0133 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0151 | 0.0856 | 0.1684 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0072 | 0.0377 | 0.1663 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0822 | 0.1618 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0024 | 0.0083 |
Onchocerca volvulus | 0.0098 | 0.0533 | 0.3077 | |
Brugia malayi | Phospholipase A2 family protein | 0.0291 | 0.1713 | 0.3372 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0166 | 0.0166 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0016 | 0.0016 |
Echinococcus multilocularis | tumor protein p63 | 0.0335 | 0.1985 | 0.1985 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0166 | 0.0202 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0103 | 0.0103 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0247 | 0.0424 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0841 | 0.5082 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0179 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.0216 | 0.1 |
Plasmodium falciparum | GAF domain-related protein, putative | 0.0038 | 0.0166 | 0.0309 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0015 | 0.0024 | 0.003 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0699 | 0.1375 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0034 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0108 | 0.0213 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.0081 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.011 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0052 | 0.0255 | 0.0501 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0072 | 0.0377 | 0.1663 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0072 | 0.0249 |
Schistosoma mansoni | lamin | 0.0028 | 0.0103 | 0.0204 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0377 | 0.0743 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0086 | 0.0459 | 0.2267 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0329 | 0.1944 | 0.6775 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 0.1372 | 0.702 |
Loa Loa (eye worm) | patched family protein | 0.0012 | 0.0009 | 0.0031 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0058 | 0.0115 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0822 | 0.1618 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0265 | 0.0925 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0009 | 0.0017 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0072 | 0.0377 | 0.0623 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0049 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0841 | 0.5082 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0377 | 0.0743 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0052 | 0.0255 | 0.0456 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.0699 | 0.0699 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0024 | 0.0083 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0058 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0265 | 0.0925 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0179 | 0.0609 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0381 | 0.075 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0166 | 0.0738 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0016 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.044 | 0.0866 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0072 | 0.0377 | 0.0623 |
Onchocerca volvulus | 0.0021 | 0.0065 | 0.0328 | |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0028 | 0.0007 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.0216 | 0.1 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0015 | 0.0024 | 0.0024 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0052 | 0.0255 | 0.0501 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0083 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.02 | 0.1157 | 0.1157 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.044 | 0.0866 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0015 | 0.0024 | 0.0083 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0166 | 0.0739 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0316 | 0.187 | 0.187 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0116 | 0.0228 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0464 | 0.2776 | 0.2776 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0235 | 0.0462 |
Toxoplasma gondii | hypothetical protein | 0.0038 | 0.0166 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.02 | 0.1157 | 0.4031 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0459 | 0.16 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0072 | 0.0377 | 0.0699 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0358 | 0.0704 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.0133 | 0.0261 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.0216 | 0.0408 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0066 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0058 | 0.0203 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0841 | 0.5082 | 1 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0054 | 0.0265 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0166 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0473 | 0.2828 | 0.2828 |
Schistosoma mansoni | lamin | 0.0028 | 0.0103 | 0.0204 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0054 | 0.0265 | 0.0459 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.0081 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0166 | 0.0326 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0058 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0377 | 0.1315 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0058 | 0.0203 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0131 | 0.0131 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0065 | 0.0081 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0034 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0058 | 0.0115 |
Echinococcus multilocularis | protein patched | 0.0086 | 0.0459 | 0.0459 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0034 | 0.0019 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0166 | 0.0739 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.006 | 0.0118 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0015 | 0.0024 | 0.0024 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0083 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.0081 |
Onchocerca volvulus | 0.0025 | 0.0089 | 0.0469 | |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.02 | 0.1157 | 0.581 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0166 | 0.0281 |
Onchocerca volvulus | 0.003 | 0.0116 | 0.0628 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0131 | 0.0131 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0021 | 0.0065 | 0.0062 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0052 | 0.0255 | 0.0501 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0131 | 0.0455 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0131 | 0.0455 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0473 | 0.2828 | 0.9854 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0032 | 0.0133 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0219 | 0.0764 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0179 | 0.0336 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0065 | 0.0225 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0058 | 0.0058 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0038 | 0.0038 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0066 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0058 | 0.0115 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Onchocerca volvulus | 0.0235 | 0.1373 | 0.8002 | |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0058 | 0.0115 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.1198 | 0.2357 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0329 | 0.1944 | 0.1944 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0133 | 0.0261 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0377 | 0.0623 |
Toxoplasma gondii | hypothetical protein | 0.0038 | 0.0166 | 0.0309 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0058 | 0.0203 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0145 | 0.0822 | 0.0822 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.048 | 0.287 | 0.287 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0058 | 0.0115 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Toxoplasma gondii | hypothetical protein | 0.0038 | 0.0166 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0255 | 0.0887 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0086 | 0.0459 | 0.16 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0072 | 0.0377 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0058 | 0.0203 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0166 | 0.0281 |
Echinococcus granulosus | lamin | 0.0028 | 0.0103 | 0.036 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0247 | 0.0424 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0131 | 0.0257 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0133 | 0.0465 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.0319 | 0.0319 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0015 | 0.0024 | 0.0024 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0381 | 0.1684 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.0341 | 0.0671 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0265 | 0.0925 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.0038 | 0.0166 | 0.0261 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0166 | 0.0326 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0015 | 0.0024 | 0.0047 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0058 | 0.029 |
Schistosoma mansoni | patched 1 | 0.0086 | 0.0459 | 0.0904 |
Echinococcus multilocularis | Ankyrin | 0.0032 | 0.0133 | 0.0133 |
Plasmodium vivax | cyclic nucleotide phosphodiesterase, putative | 0.0015 | 0.0024 | 0.003 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0015 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.048 | 0.287 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0166 | 0.0281 |
Echinococcus granulosus | Ankyrin | 0.0032 | 0.0133 | 0.0465 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0021 | 0.0065 | 0.0062 |
Schistosoma mansoni | survival motor neuron protein | 0.0098 | 0.0533 | 0.105 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0086 | 0.0459 | 0.16 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0131 | 0.0257 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0109 | 0.0381 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.0412 | 0.0811 |
Onchocerca volvulus | 0.0021 | 0.0065 | 0.0328 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0058 | 0.0115 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.0216 | 0.0752 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0316 | 0.187 | 0.6515 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0841 | 0.5082 | 1 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0052 | 0.0255 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0072 | 0.0072 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0577 | 0.2011 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0103 | 0.036 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.0554 | 0.1089 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0329 | 0.1944 | 0.3797 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0058 | 0.0115 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0381 | 0.1684 |
Onchocerca volvulus | 0.0072 | 0.0377 | 0.2162 | |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0015 | 0.0024 | 0.003 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0058 | 0.0115 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0021 | 0.0065 | 0.0127 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0103 | 0.036 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0358 | 0.1246 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0058 | 0.0115 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0103 | 0.036 |
Loa Loa (eye worm) | patched family protein | 0.0012 | 0.0009 | 0.0031 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0072 | 0.0141 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0116 | 0.0211 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0015 | 0.0024 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0058 | 0.0115 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0016 | 0.0056 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0473 | 0.2828 | 0.2828 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0065 | 0.0225 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0166 | 0.0578 |
Brugia malayi | Myosin head containing protein | 0.0012 | 0.0009 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Onchocerca volvulus | 0.0049 | 0.0235 | 0.1326 | |
Toxoplasma gondii | propionate-CoA ligase | 0.0021 | 0.0065 | 0.011 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0052 | 0.0255 | 0.0456 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0841 | 0.5082 | 1 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0841 | 0.5082 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0153 | 0.0532 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.0554 | 0.1929 |
Brugia malayi | Patched related family protein 10 | 0.0012 | 0.0009 | 0.0017 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0086 | 0.0459 | 0.0459 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0028 | 0.0054 |
Onchocerca volvulus | 0.0028 | 0.0103 | 0.0555 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0054 | 0.0265 | 0.04 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0058 | 0.0115 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0841 | 0.5082 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0554 | 0.1929 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0058 | 0.0203 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.0381 | 0.1329 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0058 | 0.0203 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0058 | 0.0115 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0065 | 0.0225 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0065 | 0.0062 |
Echinococcus granulosus | neuropeptide s receptor | 0.0473 | 0.2828 | 0.9854 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0329 | 0.1944 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0131 | 0.0131 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0166 | 0.0738 |
Loa Loa (eye worm) | patched family protein | 0.0012 | 0.0009 | 0.0031 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0464 | 0.2776 | 0.9673 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0024 | 0.0083 |
Echinococcus granulosus | tumor protein p63 | 0.0335 | 0.1985 | 0.6917 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0028 | 0.0007 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Death domain containing protein | 0.0032 | 0.0133 | 0.0261 |
Echinococcus multilocularis | protein dispatched 1 | 0.0098 | 0.0533 | 0.0533 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0058 | 0.0203 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0034 | 0.0034 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0065 | 0.0081 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0015 | 0.0024 | 0.0047 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0065 | 0.0062 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0166 | 0.0739 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0065 | 0.0213 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0032 | 0.0133 | 0.0462 |
Onchocerca volvulus | 0.002 | 0.0058 | 0.029 | |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0034 | 0.0019 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0166 | 0.0201 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0533 | 0.105 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0086 | 0.0459 | 0.16 |
Loa Loa (eye worm) | hypothetical protein | 0.0412 | 0.2456 | 0.8558 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0058 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0013 | 0.0046 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0841 | 0.5082 | 1 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0028 | 0.0007 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0841 | 0.5082 | 1 |
Brugia malayi | Patched family protein | 0.0012 | 0.0009 | 0.0017 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0072 | 0.0377 | 0.0681 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0015 | 0.0024 | 0.003 |
Onchocerca volvulus | 0.0021 | 0.0065 | 0.0328 | |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0025 | 0.0049 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0329 | 0.1944 | 0.6775 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0103 | 0.0204 |
Brugia malayi | Protein kinase domain containing protein | 0.0032 | 0.0133 | 0.0261 |
Echinococcus granulosus | expressed conserved protein | 0.0188 | 0.1083 | 0.3772 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0052 | 0.0255 | 0.1202 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0015 | 0.0024 | 0.0047 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0103 | 0.0204 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0116 | 0.0211 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.0216 | 0.0408 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0015 | 0.0024 | 0.003 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0065 | 0.0127 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0058 | 0.0115 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | > 122 uM | Cytotoxicity against human MT4 cells after 4 days by MTT method | ChEMBL. | 20043638 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.