Detailed information for compound 1083330

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 430.42 | Formula: C23H21F3N2O3
  • H donors: 1 H acceptors: 2 LogP: 5.08 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C([C@@H]1CCC[C@H]1c1occ(n1)c1ccccc1)NCc1ccc(cc1)OC(F)(F)F
  • InChi: 1S/C23H21F3N2O3/c24-23(25,26)31-17-11-9-15(10-12-17)13-27-21(29)18-7-4-8-19(18)22-28-20(14-30-22)16-5-2-1-3-6-16/h1-3,5-6,9-12,14,18-19H,4,7-8,13H2,(H,27,29)/t18-,19-/m1/s1
  • InChiKey: BCHNQKVRGBRJCE-RTBURBONSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0078 0.01 0.0148
Echinococcus granulosus tar DNA binding protein 0.0537 0.0903 0.0903
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0023 0.0437
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Toxoplasma gondii histone lysine methyltransferase SET1 0.0028 0.0011 0.0053
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0059 0.0066 0.0066
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Echinococcus multilocularis lamin dm0 0.026 0.0418 0.0418
Mycobacterium tuberculosis Probable dehydrogenase 0.007 0.0085 0.1045
Trypanosoma brucei PAB1-binding protein , putative 0.0137 0.0203 0.3909
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Schistosoma mansoni cellular tumor antigen P53 0.062 0.1048 0.1045
Loa Loa (eye worm) hypothetical protein 0.0125 0.0182 0.0271
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0006 0.0006
Brugia malayi beta-lactamase family protein 0.0064 0.0074 0.011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Plasmodium falciparum importin beta, putative 0.0028 0.0011 0.0129
Echinococcus granulosus beta LACTamase domain containing family member 0.0064 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0249 0.0323
Trypanosoma cruzi trypanothione reductase, putative 0.0031 0.0017 0.0291
Loa Loa (eye worm) hypothetical protein 0.0108 0.0152 0.0226
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0025 0.0006 0.0006
Brugia malayi Peptidase family M1 containing protein 0.0108 0.0152 0.0226
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Trichomonas vaginalis antibiotic synthetase, putative 0.0087 0.0116 0.0148
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0131 0.0131
Brugia malayi MH2 domain containing protein 0.0026 0.0009 0.0013
Schistosoma mansoni hypothetical protein 0.0078 0.01 0.0097
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0025 0.0006 0.0003
Echinococcus granulosus cathepsin l1 0.0034 0.0023 0.0023
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0222 0.0352 0.0522
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0116 0.0172
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Echinococcus multilocularis expressed protein 0.0025 0.0006 0.0006
Loa Loa (eye worm) MH1 domain-containing protein 0.0059 0.0066 0.0097
Trypanosoma cruzi aminopeptidase, putative 0.0108 0.0152 0.2969
Schistosoma mansoni tar DNA-binding protein 0.0537 0.0903 0.09
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0025 0.0006 0.0006
Schistosoma mansoni zinc finger protein 0.0061 0.0069 0.0066
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0006 0.0006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Schistosoma mansoni SET domain protein 0.0026 0.0009 0.0006
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0119 0.0172 0.336
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.003
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0025 0.0006 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Leishmania major hypothetical protein, conserved 0.0048 0.0046 0.0874
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0116 0.0172
Entamoeba histolytica acyl-CoA synthetase, putative 0.0297 0.0483 1
Schistosoma mansoni ferritin 0.0053 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0133 0.0198
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0222 0.0352 0.7125
Onchocerca volvulus Cathepsin F homolog 0.0034 0.0023 0.0026
Echinococcus granulosus methyl CpG binding domain protein 2 0.0053 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0129 0.0188 0.0188
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0025 0.0006 0.001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0297 0.0483 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0136 0.0133
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.007 0.0085 0.1045
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0039 0.0743
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0087 0.0116 0.0172
Trichomonas vaginalis ubiquitin specific protease, putative 0.0025 0.0006 0.0006
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0056 0.0053
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0108 0.0152 0.2969
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0004
Brugia malayi RNA, U transporter 1 0.0078 0.01 0.0148
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0131 0.0131
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0025 0.0006 0.0003
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0006 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0297 0.0483 1
Echinococcus granulosus ferritin 0.0053 0.0055 0.0055
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0026 0.0026
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0064 0.0074 0.0877
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0014 0.0014
Echinococcus multilocularis microtubule associated protein 2 0.5732 1 1
Loa Loa (eye worm) glutaminase 0.0211 0.0332 0.0493
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0053 0.0055 0.078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0104 0.0145 0.1954
Mycobacterium ulcerans acyl-CoA synthetase 0.0297 0.0483 1
Plasmodium vivax hypothetical protein, conserved 0.0064 0.0074 0.0732
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.0023 0.0474
Trichomonas vaginalis glucosylceramidase, putative 0.0113 0.0161 0.0207
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.026 0.0418 0.062
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0026 0.0206
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0108 0.0152 0.2903
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Mycobacterium tuberculosis Conserved protein 0.0064 0.0074 0.0877
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0294 0.0477 0.0708
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0127 0.0185 0.0274
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0104 0.0145 0.0142
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0025 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0129 0.0189 0.0186
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Schistosoma mansoni peptidase 0.0025 0.0006 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0035 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Onchocerca volvulus 0.0078 0.01 0.0126
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.2035 0.3526 0.3524
Schistosoma mansoni zinc finger protein 0.0048 0.0046 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0104 0.0145 0.2836
Leishmania major cathepsin L-like protease 0.0131 0.0192 0.3753
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0025 0.0006 0.001
Schistosoma mansoni smad1 5 8 and 0.0059 0.0066 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Schistosoma mansoni smad1 5 8 and 0.0059 0.0066 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Trypanosoma brucei aminopeptidase, putative 0.0108 0.0152 0.2903
Mycobacterium tuberculosis Putative ferredoxin reductase 0.007 0.0085 0.1045
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0026 0.0038
Mycobacterium ulcerans glutaminase 0.0211 0.0332 0.6688
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0019 0.0038
Leishmania major 4-coumarate:coa ligase-like protein 0.0297 0.0483 0.9515
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0025 0.0006 0.0006
Schistosoma mansoni lamin 0.026 0.0418 0.0415
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.0074 0.1434
Toxoplasma gondii LsmAD domain-containing protein 0.0137 0.0203 0.2113
Trypanosoma cruzi PAB1-binding protein , putative 0.0137 0.0203 0.3965
Echinococcus multilocularis zinc finger protein 0.0061 0.0069 0.0069
Brugia malayi hypothetical protein 0.0137 0.0203 0.0301
Onchocerca volvulus Alhambra homolog 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0297 0.0483 0.0718
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0025 0.0006 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Echinococcus granulosus leukotriene A 4 hydrolase 0.2035 0.3526 0.3526
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Trichomonas vaginalis penicillin-binding protein, putative 0.0064 0.0074 0.0095
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0014 0.0014
Brugia malayi hypothetical protein 0.0935 0.1601 0.2377
Schistosoma mansoni transcription factor LCR-F1 0.0129 0.0189 0.0186
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Echinococcus multilocularis tumor protein p63 0.4233 0.7376 0.7376
Loa Loa (eye worm) hypothetical protein 0.0297 0.0483 0.0718
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0129 0.0188 0.0188
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0407 0.0676 1
Brugia malayi hypothetical protein 0.0088 0.0118 0.0174
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0014 0.0082
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0164 0.0249 0.037
Mycobacterium ulcerans aldehyde dehydrogenase 0.0104 0.0145 0.2616
Brugia malayi PHD-finger family protein 0.0029 0.0014 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0039 0.0743
Toxoplasma gondii aminopeptidase N, putative 0.0108 0.0152 0.1569
Schistosoma mansoni microtubule-associated protein tau 0.5732 1 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0129 0.0189 0.0189
Schistosoma mansoni survival motor neuron protein 0.0078 0.01 0.0097
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0026 0.0382
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0116 0.1503
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0108 0.0152 0.1569
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0222 0.0352 0.0522
Plasmodium vivax vivapain-2 0.0034 0.0023 0.0177
Onchocerca volvulus 0.026 0.0418 0.0541
Mycobacterium ulcerans aldehyde dehydrogenase 0.0104 0.0145 0.2616
Entamoeba histolytica cysteine protease, putative 0.0034 0.0023 0.0437
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0025 0.0006 0.0003
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0087 0.0116 0.208
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0064 0.0074 0.0071
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0186 0.0288 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0109
Entamoeba histolytica acyl-coA synthetase, putative 0.0297 0.0483 1
Leishmania major cathepsin L-like protease 0.0131 0.0192 0.3753
Brugia malayi Smad1 0.0059 0.0066 0.0097
Echinococcus granulosus zinc finger protein 0.0061 0.0069 0.0069
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0555 0.0934 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Trypanosoma cruzi ISWI complex protein 0.0048 0.0046 0.0874
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0537 0.0903 0.1341
Mycobacterium tuberculosis Probable lipase LipD 0.0064 0.0074 0.0877
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0025 0.0006 0.0006
Plasmodium vivax vivapain-2 0.0034 0.0023 0.0177
Echinococcus multilocularis protein patched 0.0042 0.0036 0.0036
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0026 0.0031
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0109
Loa Loa (eye worm) hypothetical protein 0.0119 0.0172 0.0255
Schistosoma mansoni hypothetical protein 0.0048 0.0046 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.0192 0.3753
Trichomonas vaginalis ferritin, putative 0.0053 0.0055 0.007
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0087 0.0116 0.208
Onchocerca volvulus 0.0034 0.0023 0.0026
Brugia malayi Cytochrome P450 family protein 0.0033 0.0021 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0222 0.0352 0.0522
Mycobacterium ulcerans lipase LipD 0.0064 0.0074 0.1065
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0064 0.0074 0.011
Brugia malayi MH2 domain containing protein 0.0861 0.147 0.2183
Brugia malayi Cathepsin L-like precursor 0.0034 0.0023 0.0034
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0185 0.0286 0.0425
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0108 0.0152 0.0152
Brugia malayi Cathepsin L-like precursor 0.0034 0.0023 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0121 0.0174 0.0258
Echinococcus granulosus geminin 0.0438 0.073 0.073
Onchocerca volvulus Glucosylceramidase homolog 0.0107 0.0151 0.0193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0025 0.0006 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0023 0.0416
Brugia malayi cytoplasmic intermediate filament protein 0.0139 0.0206 0.0306
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0025 0.0006 0.001
Brugia malayi hypothetical protein 0.0086 0.0114 0.017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0034
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0297 0.0483 1
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0116 0.2177
Echinococcus multilocularis smad 0.0059 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0087 0.0116 0.1966
Leishmania major acetyl-CoA synthetase, putative 0.0087 0.0116 0.2249
Brugia malayi Cathepsin L-like precursor 0.0034 0.0023 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0087 0.0116 0.1503
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0053 0.0055 0.0052
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0108 0.0152 0.0196
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0026 0.0038
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0025 0.0006 0.0003
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0108 0.0152 0.0196
Onchocerca volvulus 0.0297 0.0483 0.0626
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0009 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) peptidase family M1 containing protein 0.0108 0.0152 0.0226
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0537 0.0903 0.1341
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0297 0.0483 0.0718
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.007 0.0085 0.1045
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0112 0.0158 0.0158
Brugia malayi TATA binding protein associated factor 0.0108 0.0152 0.0226
Leishmania major cathepsin L-like protease 0.0034 0.0023 0.0416
Echinococcus granulosus expressed conserved protein 0.0091 0.0123 0.0123
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.027 0.0436 0.0647
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0026 0.047
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0039 0.0743
Leishmania major trypanothione reductase 0.0031 0.0017 0.0291
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0014 0.0011
Trypanosoma cruzi major cysteine proteinase, putative 0.0103 0.0143 0.2785
Echinococcus granulosus mothers against decapentaplegic 2 0.0026 0.0009 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0137 0.0203 0.3965
Entamoeba histolytica hypothetical protein 0.0129 0.0189 0.3892
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0056 0.1074
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.0508 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.021 0.0331 0.4762
Brugia malayi cathepsin L-like precursor 0.0023 0.0003 0.0004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0064 0.0074 0.1065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Mycobacterium ulcerans aminopeptidase N PepN 0.0108 0.0152 0.2762
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0023 0.002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0129 0.0189 0.0189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0188 0.0185
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0024 0.0442
Schistosoma mansoni hypothetical protein 0.0025 0.0006 0.0003
Onchocerca volvulus 0.0555 0.0934 0.1214
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0025 0.0006 0.0006
Echinococcus multilocularis lamin 0.026 0.0418 0.0418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0003 0.0002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0087 0.0116 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0036 0.0044
Loa Loa (eye worm) hypothetical protein 0.0383 0.0634 0.0941
Schistosoma mansoni hypothetical protein 0.0438 0.073 0.0727
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0222 0.0352 0.5084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni glutaminase 0.0211 0.0332 0.0329
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0025 0.0006 0.0003
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0087 0.0116 0.1503
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0137 0.0203 0.3965
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0024 0.0442
Plasmodium falciparum phd finger protein, putative 0.0029 0.0014 0.022
Brugia malayi Thioredoxin reductase 0.0031 0.0017 0.0025
Brugia malayi Inositol-1 0.0036 0.0026 0.0038
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0026 0.0038
Toxoplasma gondii hypothetical protein 0.005 0.0051 0.0476
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0025 0.0006 0.0003
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0087 0.0116 0.1503
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0087 0.0116 0.1966
Onchocerca volvulus 0.0087 0.0116 0.0147
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0108 0.0152 0.2969
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Schistosoma mansoni hypothetical protein 0.0185 0.0286 0.0283
Leishmania major cathepsin L-like protease 0.0034 0.0023 0.0416
Echinococcus multilocularis expressed conserved protein 0.0091 0.0123 0.0123
Echinococcus granulosus intermediate filament protein 0.026 0.0418 0.0418
Echinococcus multilocularis thioredoxin glutathione reductase 0.0031 0.0017 0.0017
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0116 0.0172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0025 0.0006 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0064 0.0074 0.0095
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0104 0.0145 0.0145
Echinococcus multilocularis leukotriene A 4 hydrolase 0.2035 0.3526 0.3526
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0025 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0537 0.0903 0.09
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0087 0.0116 0.2177
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0086 0.0114 0.017
Loa Loa (eye worm) hypothetical protein 0.0608 0.1027 0.1525
Loa Loa (eye worm) Smad1 0.0059 0.0066 0.0097
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0139 0.0206 0.0306
Entamoeba histolytica aminopeptidase, putative 0.0108 0.0152 0.312
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.0113 0.0161 0.0207
Onchocerca volvulus 0.0034 0.0023 0.0026
Schistosoma mansoni patched 1 0.0042 0.0036 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0249 0.0323
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0025 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0064 0.0074 0.0877
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Onchocerca volvulus 0.0034 0.0023 0.0026
Echinococcus multilocularis ferritin 0.0053 0.0055 0.0055
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0061 0.007 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major mitochondrial DNA polymerase beta 0.0311 0.0508 1
Mycobacterium tuberculosis Conserved protein 0.0064 0.0074 0.0877
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0034 0.0034
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Onchocerca volvulus 0.0087 0.0116 0.0147
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.0023 0.0023
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0087 0.0116 0.1503
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0087 0.0116 0.1966
Loa Loa (eye worm) inositol-1 0.0036 0.0026 0.0038
Brugia malayi intermediate filament protein 0.026 0.0418 0.062
Plasmodium vivax acetyl-CoA synthetase, putative 0.0087 0.0116 0.1176
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0206 0.0206
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0116 0.2249
Schistosoma mansoni ferritin 0.0053 0.0055 0.0052
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0249 0.0323
Echinococcus granulosus lamin 0.026 0.0418 0.0418
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0108 0.0152 0.0149
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0108 0.0152 0.2969
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Mycobacterium ulcerans aminopeptidase N PepN 0.0108 0.0152 0.2762
Echinococcus multilocularis ubiquitin specific protease 41 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0064 0.0074 0.011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0064 0.0074 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0297 0.0483 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.021 0.0331 0.4762
Brugia malayi RNA binding protein 0.0537 0.0903 0.1341
Loa Loa (eye worm) glutaminase 2 0.0211 0.0332 0.0493
Loa Loa (eye worm) hypothetical protein 0.0255 0.0409 0.0608
Brugia malayi hypothetical protein 0.0108 0.0152 0.0226
Onchocerca volvulus 0.0108 0.0152 0.0194
Onchocerca volvulus 0.0108 0.0152 0.0194
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0087 0.0116 0.1176
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0026 0.0009 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0555 0.0934 0.0932
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.021 0.0331 0.4762
Brugia malayi Bromodomain containing protein 0.0037 0.0027 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0064 0.0074 0.011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Brugia malayi beta-lactamase 0.0064 0.0074 0.011
Loa Loa (eye worm) aminopeptidase N 0.0108 0.0152 0.0226
Schistosoma mansoni Smad4 0.0026 0.0009 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi aminopeptidase, putative 0.0108 0.0152 0.2969
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Mycobacterium tuberculosis Probable lipase LipE 0.0064 0.0074 0.0877
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0021
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0085 0.0112 0.0112
Entamoeba histolytica hypothetical protein 0.0129 0.0189 0.3892
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0026 0.0031
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0026 0.0026
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0116 0.1503
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus granulosus GPCR family 2 0.0085 0.0112 0.0112
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0108 0.0152 0.2969
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0009 0.0013
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0006 0.0006
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0025 0.0006 0.0003
Schistosoma mansoni Smad4 0.0059 0.0066 0.0063
Loa Loa (eye worm) beta-lactamase 0.0064 0.0074 0.011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Loa Loa (eye worm) hypothetical protein 0.062 0.1048 0.1556
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0025 0.0006 0.0006
Echinococcus granulosus cathepsin l1 0.0023 0.0003 0.0003
Plasmodium vivax SET domain containing protein 0.0028 0.0011 0.0053
Plasmodium vivax glutathione reductase, putative 0.0031 0.0017 0.0108
Loa Loa (eye worm) hypothetical protein 0.0042 0.0036 0.0053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.021 0.0331 0.4762
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0085 0.0112 0.0112
Loa Loa (eye worm) ctsf protein 0.0034 0.0023 0.0034
Brugia malayi Cathepsin L-like precursor 0.0034 0.0023 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Onchocerca volvulus 0.062 0.1048 0.1362
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0011 0.0089
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0025 0.0006 0.0003
Schistosoma mansoni lipoxygenase 0.0064 0.0074 0.0071
Schistosoma mansoni ferritin 0.0053 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0097 0.0133 0.0198
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0025 0.0006 0.0006
Plasmodium falciparum glutathione reductase 0.0031 0.0017 0.0291
Leishmania major 4-coumarate:coa ligase-like protein 0.0297 0.0483 0.9515
Echinococcus multilocularis mothers against decapentaplegic 5 0.0059 0.0066 0.0066
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0091 0.0122 0.0122
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0064 0.0074 0.011
Brugia malayi mothers against decapentaplegic homolog 3 0.0026 0.0009 0.0013
Schistosoma mansoni aminopeptidase A (M01 family) 0.0108 0.0152 0.0149
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0297 0.0483 0.708
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.007 0.0085 0.143
Onchocerca volvulus 0.0025 0.0006 0.0005
Brugia malayi MH1 domain containing protein 0.0032 0.002 0.0029
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3051 0.5305 0.5305
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0053 0.0055 0.0055
Loa Loa (eye worm) oxidoreductase 0.0087 0.0116 0.0172
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0023 0.0023
Brugia malayi hypothetical protein 0.0383 0.0634 0.0941
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0011 0.0048
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0087 0.0116 0.1966
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0026 0.047
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Toxoplasma gondii thioredoxin reductase 0.0031 0.0017 0.0108
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0164 0.0249 0.037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.0034 0.0023 0.0416
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Schistosoma mansoni apoferritin-2 0.0053 0.0055 0.0052
Brugia malayi MH2 domain containing protein 0.0059 0.0066 0.0097
Onchocerca volvulus 0.0064 0.0074 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0608 0.1027 0.1024
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0069 0.0102
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0053 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0109
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0116 0.0172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0087 0.0116 0.1966
Brugia malayi TAR-binding protein 0.0537 0.0903 0.1341
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0116 0.2249
Loa Loa (eye worm) intermediate filament protein 0.026 0.0418 0.062
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Brugia malayi MH1 domain containing protein 0.0059 0.0066 0.0097
Brugia malayi Importin beta-1 subunit 0.0028 0.0011 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0137 0.0203 0.5677
Onchocerca volvulus 0.0064 0.0074 0.0093
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0006 0.0003
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Mycobacterium tuberculosis Conserved protein 0.0064 0.0074 0.0877
Schistosoma mansoni hypothetical protein 0.0029 0.0014 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0555 0.0934 0.0932
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0014 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Mycobacterium ulcerans esterase/lipase LipP 0.0064 0.0074 0.1065
Brugia malayi MH1 domain containing protein 0.0032 0.002 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Toxoplasma gondii cathepsin CPL 0.0034 0.0023 0.0177
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0053 0.0055 0.0081
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0026 0.0031
Leishmania major cysteine peptidase A (CPA) 0.0034 0.0023 0.0416
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0861 0.147 0.2183
Echinococcus multilocularis expressed protein 0.0036 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0108 0.0152 0.1569
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.0034 0.0023 0.0416
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0297 0.0483 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0051 0.0075
Loa Loa (eye worm) leukotriene A4 hydrolase 0.2035 0.3526 0.5234
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0087 0.0116 0.0116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus granulosus aminopeptidase N 0.0108 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0035 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Echinococcus granulosus expressed protein 0.0053 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major acetyl-CoA synthetase, putative 0.0087 0.0116 0.2249
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Loa Loa (eye worm) nuclear factor I 0.0032 0.002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0016
Echinococcus granulosus snurportin 1 0.0294 0.0477 0.0477
Echinococcus granulosus thioredoxin glutathione reductase 0.0031 0.0017 0.0017
Onchocerca volvulus Huntingtin homolog 0.0086 0.0114 0.0145
Schistosoma mansoni lipoxygenase 0.0091 0.0122 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0087 0.0116 0.2363
Schistosoma mansoni tar DNA-binding protein 0.0537 0.0903 0.09
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Schistosoma mansoni inositol monophosphatase 0.0036 0.0026 0.0023
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.0192 0.3753
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0116 0.1503
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0004
Echinococcus granulosus smad 0.0059 0.0066 0.0066
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.0023 0.0474
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0056 0.0053
Entamoeba histolytica hypothetical protein 0.0129 0.0189 0.3892
Loa Loa (eye worm) hypothetical protein 0.0222 0.0352 0.0522
Mycobacterium ulcerans hypothetical protein 0.0164 0.025 0.49
Onchocerca volvulus 0.0087 0.0116 0.0147
Toxoplasma gondii aminopeptidase n, putative 0.0108 0.0152 0.1569
Loa Loa (eye worm) PHD-finger family protein 0.0064 0.0075 0.0112
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0297 0.0483 0.708
Echinococcus multilocularis snurportin 1 0.0294 0.0477 0.0477
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0053 0.0055 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0064 0.0074 0.1065
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0087 0.0116 0.0172
Trypanosoma brucei trypanothione reductase 0.0031 0.0017 0.0201
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Onchocerca volvulus 0.0034 0.0023 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0608 0.1027 0.1024
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Brugia malayi Cathepsin L-like precursor 0.0023 0.0003 0.0004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0025 0.0006 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0085 0.0112 0.0167
Brugia malayi jmjC domain containing protein 0.0041 0.0035 0.0052
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0006 0.0006
Schistosoma mansoni smad 0.0026 0.0009 0.0006
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0078 0.0099 0.1253
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Plasmodium vivax thioredoxin reductase, putative 0.0031 0.0017 0.0108
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0053 0.0055 0.0055
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0023 0.0023
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0026 0.0494
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0025 0.0006 0.0003
Schistosoma mansoni hypothetical protein 0.0438 0.073 0.0727
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0087 0.0116 0.1503
Brugia malayi AMP-binding enzyme family protein 0.0297 0.0483 0.0718
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0025 0.0006 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0006 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0861 0.147 0.2183
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0023 0.0027
Trichomonas vaginalis antibiotic synthetase, putative 0.0087 0.0116 0.0148
Loa Loa (eye worm) hypothetical protein 0.0064 0.0074 0.011
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0085 0.0112 0.0112
Mycobacterium ulcerans bacterioferritin BfrB 0.0053 0.0055 0.0647
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0006 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0064 0.0074 0.1354
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0125 0.0182 0.0182
Brugia malayi Calcitonin receptor-like protein seb-1 0.027 0.0436 0.0647
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0061 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni ferritin light chain 0.0053 0.0055 0.0052
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus granulosus survival motor neuron protein 1 0.0383 0.0634 0.0634
Brugia malayi glutaminase DH11.1 0.0211 0.0332 0.0493
Plasmodium falciparum thioredoxin reductase 0.0031 0.0017 0.0291
Plasmodium vivax acyl-CoA synthetase, putative 0.0222 0.0352 0.3722
Echinococcus multilocularis cysteine protease 0.0034 0.0023 0.0023
Trichomonas vaginalis esterase, putative 0.0064 0.0074 0.0095
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0014 0.0082
Mycobacterium leprae Probable lipase LipE 0.0064 0.0074 0.1192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0006 0.0006
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0011 0.0089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0297 0.0483 0.0718
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0116 0.1966
Onchocerca volvulus Huntingtin homolog 0.0086 0.0114 0.0145
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0025 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0053 0.0055 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0085 0.0112 0.0167
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.0023 0.0474
Echinococcus multilocularis GPCR, family 2 0.0085 0.0112 0.0112
Brugia malayi Intermediate filament tail domain containing protein 0.026 0.0418 0.062
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Brugia malayi MH2 domain containing protein 0.0059 0.0066 0.0097
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0087 0.0116 0.2249
Trichomonas vaginalis set domain proteins, putative 0.4402 0.7672 1
Echinococcus multilocularis protein dispatched 1 0.0048 0.0046 0.0046
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0297 0.0483 1
Echinococcus multilocularis aminopeptidase N 0.0108 0.0152 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0297 0.0483 1
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0025 0.0006 0.0003
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0023 0.0437
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Loa Loa (eye worm) thioredoxin reductase 0.0031 0.0017 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0064 0.0074 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus granulosus importin subunit beta 1 0.0028 0.0011 0.0011
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Echinococcus granulosus Smad4 0.0059 0.0066 0.0066
Echinococcus granulosus histone lysine methyltransferase setb 0.0608 0.1027 0.1027
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0023 0.0026
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Echinococcus granulosus mothers against decapentaplegic 6 0.0026 0.0009 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0129 0.0188 0.028
Toxoplasma gondii aldehyde dehydrogenase 0.0104 0.0145 0.1497
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0108 0.0152 0.0149
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0116 0.2249
Loa Loa (eye worm) hypothetical protein 0.0222 0.0352 0.0522
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0555 0.0934 0.0934
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Onchocerca volvulus 0.0064 0.0074 0.0093
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0064 0.0074 0.011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0023 0.002
Brugia malayi Peptidase family M1 containing protein 0.0108 0.0152 0.0226
Brugia malayi Bromodomain containing protein 0.0233 0.0371 0.0551
Schistosoma mansoni rotamase 0.0036 0.0026 0.0023
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0087 0.0116 0.1966
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0108 0.0152 0.2969
Loa Loa (eye worm) hypothetical protein 0.0108 0.0152 0.0226
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0108 0.0152 0.0196
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0085 0.0112 0.0167
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0222 0.0352 0.5
Schistosoma mansoni Smad4 0.0026 0.0009 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0297 0.0483 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0087 0.0116 0.0172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.0137 0.0203 0.5677
Loa Loa (eye worm) hypothetical protein 0.0297 0.0483 0.0718
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Brugia malayi Pre-SET motif family protein 0.0555 0.0934 0.1387
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0025 0.0006 0.0006
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus granulosus peregrin 0.0037 0.0027 0.0027
Trypanosoma brucei Aminopeptidase M1, putative 0.0108 0.0152 0.2903
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) TATA binding protein associated factor 0.0108 0.0152 0.0226
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0534 0.0899 0.0899
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Loa Loa (eye worm) hypothetical protein 0.0121 0.0174 0.0258
Brugia malayi MH1 domain containing protein 0.0059 0.0066 0.0097
Echinococcus granulosus lamin dm0 0.026 0.0418 0.0418
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0025 0.0006 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi Bromodomain containing protein 0.0119 0.0171 0.0254
Brugia malayi PHD-finger family protein 0.0077 0.0098 0.0146
Loa Loa (eye worm) pigment dispersing factor receptor c 0.027 0.0436 0.0647
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0064 0.0075 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Brugia malayi beta-lactamase family protein 0.0064 0.0074 0.011
Brugia malayi Pre-SET motif family protein 0.3868 0.6736 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0221 0.4273
Plasmodium vivax ataxin-2 like protein, putative 0.0137 0.0203 0.2113
Schistosoma mansoni intermediate filament proteins 0.026 0.0418 0.0415
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0104 0.0145 0.0145
Echinococcus granulosus mothers against decapentaplegic 5 0.0059 0.0066 0.0066
Loa Loa (eye worm) bromodomain containing protein 0.0055 0.0059 0.0088
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0108 0.0152 0.2969
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0094 0.118
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0013
Schistosoma mansoni hypothetical protein 0.0294 0.0477 0.0474
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0129 0.0188 0.028
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0025 0.0006 0.0006
Trypanosoma cruzi ISWI complex protein 0.0048 0.0046 0.0874
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0297 0.0483 0.9515
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Trichomonas vaginalis rotamase, putative 0.0035 0.0024 0.0029
Trichomonas vaginalis glutaminase, putative 0.0211 0.0332 0.043
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0078 0.0099 0.1725
Toxoplasma gondii ABC1 family protein 0.0064 0.0074 0.0732
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0025 0.0006 0.0006
Brugia malayi hypothetical protein 0.0025 0.0006 0.001
Onchocerca volvulus 0.0034 0.0023 0.0026
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Schistosoma mansoni lamin 0.026 0.0418 0.0415
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0087 0.0116 0.1503
Echinococcus multilocularis fetal alzheimer antigen, falz 0.007 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.003
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0023 0.0026
Echinococcus multilocularis expressed protein 0.0053 0.0055 0.0055
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0024 0.0465
Onchocerca volvulus 0.0108 0.0152 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0311 0.0508 1
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0087 0.0116 0.1966
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus granulosus tumor protein p63 0.4233 0.7376 0.7376
Loa Loa (eye worm) TAR-binding protein 0.0537 0.0903 0.1341
Brugia malayi Cathepsin L-like precursor 0.0034 0.0023 0.0034
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0133 0.0133
Brugia malayi CHE-14 protein 0.0042 0.0036 0.0053
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0025 0.0006 0.0006
Brugia malayi Latrophilin receptor protein 2 0.0085 0.0112 0.0167
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0108 0.0152 0.4216
Loa Loa (eye worm) hypothetical protein 0.0108 0.0152 0.0226
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0015 0.0012
Echinococcus granulosus expressed protein 0.0036 0.0026 0.0026
Schistosoma mansoni smad 0.0059 0.0066 0.0063
Onchocerca volvulus 0.0025 0.0006 0.0005
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0087 0.0116 0.1176
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0025 0.0006 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0025 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0129 0.0189 0.3892
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0608 0.1027 0.1027
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.0074 0.1434
Loa Loa (eye worm) hypothetical protein 0.0087 0.0116 0.0172
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0039 0.0657
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0221 0.4326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0078
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0108 0.0152 0.4216
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Onchocerca volvulus 0.0034 0.0023 0.0026
Trypanosoma cruzi Aminopeptidase M1, putative 0.0108 0.0152 0.2969
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0024 0.0354
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.007 0.0085 0.1045
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0108 0.0152 0.2969
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0006 0.0092
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Schistosoma mansoni importin beta-1 0.0028 0.0011 0.0008
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0025 0.0006 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0003 0.0024
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0026 0.047
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium leprae conserved hypothetical protein 0.0064 0.0074 0.1192
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0186 0.0288 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi Peptidase family M1 containing protein 0.0108 0.0152 0.0226
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0025 0.0006 0.0006
Schistosoma mansoni aldehyde dehydrogenase 0.0104 0.0145 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0025 0.0006 0.0006
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0025 0.0006 0.0006
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0061 0.007 0.007
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0024 0.0191
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0035 0.0052
Echinococcus multilocularis musashi 0.026 0.0418 0.0418
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Brugia malayi latrophilin 2 splice variant baaae 0.0185 0.0286 0.0425
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.007 0.0086 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Mycobacterium ulcerans beta-lactamase 0.0064 0.0074 0.1065
Onchocerca volvulus 0.0034 0.0023 0.0026
Schistosoma mansoni inositol monophosphatase 0.0036 0.0026 0.0023
Echinococcus multilocularis mothers against decapentaplegic 2 0.0026 0.0009 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0133 0.0133
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0087 0.0116 0.208
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0108 0.0152 0.2969
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0087 0.0116 0.2249
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0006 0.0006
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0006 0.0006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0078 0.0099 0.1253
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0188 0.0185
Schistosoma mansoni smad1 5 8 and 0.0059 0.0066 0.0063
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0125 0.0182 0.0182
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0025 0.0006 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi hypothetical protein 0.0108 0.0152 0.0226
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0025 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Brugia malayi jmjC domain containing protein 0.0096 0.0131 0.0194
Echinococcus multilocularis beta LACTamase domain containing family member 0.0064 0.0074 0.0074
Mycobacterium ulcerans acetyl-CoA synthetase 0.0087 0.0116 0.1966
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trypanosoma brucei Aminopeptidase M1, putative 0.0108 0.0152 0.2903
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.0508 1
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0025 0.0006 0.0003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0097
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Echinococcus multilocularis peregrin 0.0037 0.0027 0.0027
Trichomonas vaginalis ubiquitin specific protease, putative 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0025 0.0006 0.0006
Schistosoma mansoni ferritin 0.0053 0.0055 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.025 0.3539
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.026 0.0418 0.062
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0064 0.0074 0.0877
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0025 0.0006 0.0097
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0023 0.0027
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0053 0.0056 0.0056
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.3868 0.6736 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0206 0.0206
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0116 0.1503
Mycobacterium tuberculosis Probable hydrolase 0.0064 0.0074 0.0877
Trypanosoma cruzi cruzipain precursor, putative 0.0131 0.0192 0.3753
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0025 0.0006 0.0006
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0091 0.0122 0.0122
Echinococcus granulosus fetal alzheimer antigen falz 0.007 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0297 0.0483 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Loa Loa (eye worm) RNA binding protein 0.0537 0.0903 0.1341
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0108 0.0152 0.2969
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0006 0.0006
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Echinococcus granulosus ubiquitin specific protease 41 0.0025 0.0006 0.0006
Echinococcus multilocularis tar DNA binding protein 0.0537 0.0903 0.0903
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0025 0.0006 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0188 0.0185
Loa Loa (eye worm) hypothetical protein 0.0137 0.0203 0.0301
Leishmania major cathepsin L-like protease 0.0131 0.0192 0.3753
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Giardia lamblia PHD finger protein 15 0.0029 0.0014 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0025 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0537 0.0903 0.09
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0087 0.0116 0.0172
Mycobacterium ulcerans acyl-CoA synthetase 0.0297 0.0483 1
Schistosoma mansoni acetyl-CoA synthetase 0.0087 0.0116 0.0113
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0006 0.001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0133 0.2725
Loa Loa (eye worm) hypothetical protein 0.022 0.0348 0.0516
Loa Loa (eye worm) hypothetical protein 0.027 0.0436 0.0647
Plasmodium falciparum acyl-CoA synthetase 0.0222 0.0352 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0087 0.0116 0.1503
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0025 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.0151 0.0194
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0221 0.4326
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Plasmodium vivax SET domain protein, putative 0.0555 0.0934 1
Brugia malayi Cathepsin L-like precursor 0.0023 0.0003 0.0004
Leishmania major cathepsin L-like protease 0.0034 0.0023 0.0416
Echinococcus granulosus ubiquitin specific peptidase c family 0.0025 0.0006 0.0006
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0087 0.0116 0.3161
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0006 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0249 0.0323
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0129 0.0188 0.0188
Onchocerca volvulus 0.026 0.0418 0.0541
Schistosoma mansoni bromodomain containing protein 0.0197 0.0307 0.0304
Loa Loa (eye worm) hypothetical protein 0.0064 0.0074 0.011
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0025 0.0006 0.0003
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0036 0.0036
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0087 0.0116 0.1966
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0021 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi Cathepsin L-like precursor 0.0034 0.0023 0.0034
Trypanosoma brucei ISWI complex protein 0.0048 0.0046 0.0789
Echinococcus granulosus TGF beta signal transducer SmadC 0.0059 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Onchocerca volvulus 0.0025 0.0006 0.0005
Mycobacterium tuberculosis Probable esterase LipL 0.0064 0.0074 0.0877
Trichomonas vaginalis D-aminoacylase, putative 0.0064 0.0074 0.0095
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0096 0.0093
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0026 0.0031
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0129 0.0188 0.0188
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Plasmodium vivax importin-beta 2, putative 0.0028 0.0011 0.0048
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0112 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.001
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0064 0.0074 0.0095
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0006 0.0092
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0053 0.0055 0.0587
Mycobacterium ulcerans bacterioferritin BfrA 0.0053 0.0055 0.0647
Mycobacterium ulcerans aldehyde dehydrogenase 0.0104 0.0145 0.2616
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Onchocerca volvulus 0.0026 0.0009 0.0008
Echinococcus multilocularis cysteine protease 0.0034 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Brugia malayi hypothetical protein 0.0129 0.0189 0.0281
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0006 0.0092
Brugia malayi glutathione reductase 0.0031 0.0017 0.0025
Mycobacterium tuberculosis Probable oxidoreductase 0.0078 0.0099 0.1253
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0059 0.0066 0.0063
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0097
Schistosoma mansoni apoferritin-2 0.0053 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0133 0.0195 0.0289
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis rotamase, putative 0.0036 0.0026 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0087 0.0116 0.1176
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Brugia malayi ubiquitin specific protease 14 0.0025 0.0006 0.001
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0087 0.0116 0.0116
Toxoplasma gondii aminopeptidase N protein 0.0108 0.0152 0.1569
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.0192 0.3753
Echinococcus multilocularis mothers against decapentaplegic 6 0.0026 0.0009 0.0009
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0024 0.0442
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0085 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0006
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0053 0.0055 0.0055
Echinococcus multilocularis survival motor neuron protein 1 0.0383 0.0634 0.0634
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0036 0.0053
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0053 0.0055 0.0587
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0108 0.0152 0.0149
Schistosoma mansoni tar DNA-binding protein 0.0537 0.0903 0.09
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0249 0.0323
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Mycobacterium tuberculosis Probable reductase 0.007 0.0085 0.1045
Echinococcus multilocularis Smad4 0.0059 0.0066 0.0066
Loa Loa (eye worm) cysteine protease 0.0034 0.0023 0.0034
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0025 0.0006 0.0003
Leishmania major hypothetical protein, conserved 0.0064 0.0074 0.1434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0192 0.3695
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0249 0.0323
Loa Loa (eye worm) MH2 domain-containing protein 0.0059 0.0066 0.0097
Loa Loa (eye worm) fibroinase 0.0034 0.0023 0.0034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0086 0.0114 0.017
Loa Loa (eye worm) hypothetical protein 0.0064 0.0074 0.011
Brugia malayi SET domain containing protein 0.0026 0.0009 0.0013
Echinococcus multilocularis geminin 0.0438 0.073 0.073
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.0023 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0006 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0006 0.0097
Schistosoma mansoni ferritin light chain 0.0053 0.0055 0.0052
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0006 0.0006
Trichomonas vaginalis ubiquitin specific protease, putative 0.0025 0.0006 0.0006
Loa Loa (eye worm) glutathione reductase 0.0031 0.0017 0.0025
Onchocerca volvulus 0.4402 0.7672 1
Treponema pallidum bacterioferrin (TpF1) 0.0053 0.0055 0.5
Onchocerca volvulus 0.0087 0.0116 0.0147

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 19 % Inhibition of human Nav1.7 channel expressed in HEK cells at 1 uM by FRET assay ChEMBL. 19674896

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.