Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.1423 | 0.1314 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.1102 | 0.1364 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.0294 | 0.13 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.0837 | 0.5482 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.008 | 0.1423 | 0.1314 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.018 | 0.0202 |
Onchocerca volvulus | 0.008 | 0.1423 | 0.64 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0596 | 0.4432 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.008 | 0.1423 | 0.1821 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0448 | 0.8765 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.008 | 0.1423 | 0.1783 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0037 | 0.0576 | 0.0737 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.1491 |
Loa Loa (eye worm) | TAR-binding protein | 0.0201 | 0.3846 | 0.4921 |
Onchocerca volvulus | 0.0055 | 0.0918 | 0.403 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.1982 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0128 | 0.238 | 0.2284 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | TAR-binding protein | 0.0201 | 0.3846 | 0.4921 |
Loa Loa (eye worm) | beta-lactamase | 0.008 | 0.1423 | 0.1821 |
Brugia malayi | beta-lactamase | 0.008 | 0.1423 | 0.182 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0294 | 0.13 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0059 | 0.0075 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.1423 | 0.1314 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0059 | 0.0075 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0037 | 0.0576 | 0.3474 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.219 | 0.2802 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0059 | 0.0075 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0037 | 0.0576 | 0.3474 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0059 | 0.0065 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0837 | 1 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0567 | 0.0644 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0384 | 0.0492 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0294 | 0.0376 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.1423 | 1 |
Brugia malayi | glutathione reductase | 0.005 | 0.0837 | 0.107 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.018 | 0.042 |
Brugia malayi | hypothetical protein | 0.0118 | 0.219 | 0.2802 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0837 | 0.107 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.3846 | 0.4952 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0193 | 0.0209 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.1102 | 0.141 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0193 | 0.0526 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0193 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5159 | 0.66 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.1004 | 0.1236 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0059 | 0.0075 |
Onchocerca volvulus | Huntingtin homolog | 0.0118 | 0.219 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0115 | 0.2124 | 0.2025 |
Mycobacterium ulcerans | hypothetical protein | 0.008 | 0.1423 | 0.2395 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0037 | 0.0576 | 0.6033 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0252 | 0.4863 | 0.6222 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0193 | 0.0026 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0384 | 0.0425 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0059 | 0.0065 |
Brugia malayi | Augmenter of liver regeneration | 0.0037 | 0.0576 | 0.0737 |
Schistosoma mansoni | glutaminase | 0.0287 | 0.5545 | 0.7173 |
Brugia malayi | MH2 domain containing protein | 0.0115 | 0.213 | 0.2725 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1102 | 0.7529 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.008 | 0.1423 | 0.1821 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0037 | 0.0576 | 0.3474 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.1982 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0193 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0228 | 0.4376 | 0.4991 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0059 | 0.0075 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.1199 | 0.8276 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0059 | 0.0065 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Trypanosoma brucei | hypothetical protein, conserved | 0.008 | 0.1423 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.3271 | 0.4185 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0059 | 0.0075 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0596 | 0.4432 |
Onchocerca volvulus | 0.0028 | 0.0384 | 0.1526 | |
Brugia malayi | cytochrome P450 | 0.0015 | 0.0125 | 0.016 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0596 | 0.0702 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0193 | 0.0218 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0115 | 0.2124 | 0.2025 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.1423 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.008 | 0.1423 | 0.1622 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0416 | 0.0467 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0837 | 0.0952 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0059 | 0.0075 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0416 | 0.0467 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.0294 | 0.0311 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0059 | 0.0075 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0037 | 0.0576 | 0.0655 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0384 | 0.0491 |
Brugia malayi | hypothetical protein | 0.0267 | 0.5159 | 0.66 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0015 | 0.0125 | 0.014 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0115 | 0.213 | 0.2725 |
Mycobacterium ulcerans | lipase LipD | 0.008 | 0.1423 | 0.2395 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.1102 | 0.1255 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.018 | 0.042 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0055 | 0.0936 | 0.1198 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0416 | 0.0472 |
Onchocerca volvulus | 0.008 | 0.1423 | 0.64 | |
Mycobacterium leprae | conserved hypothetical protein | 0.008 | 0.1423 | 0.5755 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0087 | 0.0111 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0823 | 0.0936 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0823 | 0.0999 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.018 | 0.042 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0059 | 0.0075 |
Trichomonas vaginalis | esterase, putative | 0.008 | 0.1423 | 0.2317 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0193 | 0.0069 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0115 | 0.2124 | 0.8865 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0059 | 0.0065 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.0294 | 0.13 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0017 | 0.018 | 0.0101 |
Loa Loa (eye worm) | cytochrome P450 | 0.0015 | 0.0125 | 0.016 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.008 | 0.1423 | 0.1621 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.018 | 0.023 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0037 | 0.0576 | 0.3474 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.1199 | 0.1366 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.1423 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0448 | 0.8765 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0401 | 0.7816 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0193 | 0.0218 |
Schistosoma mansoni | survival motor neuron protein | 0.0055 | 0.0918 | 0.1123 |
Plasmodium vivax | hypothetical protein, conserved | 0.008 | 0.1423 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.8276 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0193 | 0.0526 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0823 | 0.0936 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0193 | 0.0176 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0017 | 0.018 | 0.042 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0128 | 0.238 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0567 | 0.0644 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0837 | 0.5284 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0115 | 0.2124 | 0.2025 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0596 | 0.0702 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.1423 | 0.2317 |
Brugia malayi | glutaminase DH11.1 | 0.0287 | 0.5545 | 0.7094 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0596 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0823 | 0.0936 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0193 | 0.0247 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0823 | 0.0999 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0228 | 0.4376 | 0.4991 |
Brugia malayi | Cytochrome P450 family protein | 0.0055 | 0.0936 | 0.1198 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.018 | 0.042 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0193 | 0.0026 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.008 | 0.1423 | 0.2395 |
Mycobacterium ulcerans | beta-lactamase | 0.008 | 0.1423 | 0.2395 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0055 | 0.0918 | 0.1174 |
Brugia malayi | RNA binding protein | 0.0201 | 0.3846 | 0.4921 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0115 | 0.2124 | 0.2025 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0125 | 0.016 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.018 | 0.042 |
Mycobacterium tuberculosis | Probable reductase | 0.0115 | 0.2124 | 0.2025 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0059 | 0.0065 |
Echinococcus granulosus | tar DNA binding protein | 0.0201 | 0.3846 | 0.4386 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0087 | 0.0111 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0823 | 0.1053 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.219 | 0.2802 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0059 | 0.0075 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0837 | 0.5482 |
Echinococcus multilocularis | GPCR, family 2 | 0.008 | 0.1423 | 0.1622 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0059 | 0.0075 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.1423 | 0.1314 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0059 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.1423 | 0.1784 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.008 | 0.1423 | 0.2395 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0059 | 0.0065 |
Mycobacterium ulcerans | glutaminase | 0.0287 | 0.5545 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0015 | 0.0125 | 0.0087 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Loa Loa (eye worm) | glutaminase 2 | 0.0287 | 0.5545 | 0.7094 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0837 | 0.107 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0017 | 0.018 | 0.0055 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.008 | 0.1423 | 0.1783 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0017 | 0.018 | 0.042 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.1102 | 0.1255 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1102 | 0.7529 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0059 | 0.0065 |
Leishmania major | trypanothione reductase | 0.005 | 0.0837 | 0.5482 |
Mycobacterium tuberculosis | Probable hydrolase | 0.008 | 0.1423 | 0.1314 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0002 | 0.0003 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Mycobacterium leprae | Probable lipase LipE | 0.008 | 0.1423 | 0.5755 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.018 | 0.0202 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0064 | 0.1102 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0059 | 0.0065 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0128 | 0.238 | 0.2284 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0193 | 0.0247 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0059 | 0.0065 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0294 | 0.13 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0059 | 0.0065 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0059 | 0.0075 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0879 | 0.5808 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0037 | 0.0576 | 0.0655 |
Loa Loa (eye worm) | RNA binding protein | 0.0201 | 0.3846 | 0.4921 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.1491 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0395 | 0.7707 | 0.8792 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0115 | 0.2124 | 0.2025 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0059 | 0.0065 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0837 | 0.5482 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0059 | 0.0065 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0059 | 0.0075 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0037 | 0.0576 | 0.3474 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.3846 | 0.4952 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1102 | 0.7529 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0059 | 0.0065 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0823 | 0.0936 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.1982 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0059 | 0.0075 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0201 | 0.3846 | 0.4921 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | Latrophilin receptor protein 2 | 0.008 | 0.1423 | 0.1821 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0017 | 0.018 | 0.0101 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.1102 | 0.141 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0837 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.008 | 0.1423 | 0.1621 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0059 | 0.0075 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0837 | 0.5284 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0059 | 0.0075 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.008 | 0.1423 | 0.2317 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.008 | 0.1423 | 0.1314 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0173 | 0.3271 | 0.4185 |
Echinococcus multilocularis | 0.0015 | 0.0125 | 0.014 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0059 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.1423 | 0.1784 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.008 | 0.1423 | 0.1314 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0596 | 0.0678 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0823 | 0.0999 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0294 | 0.0376 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.3271 | 0.42 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.1199 | 0.1088 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0448 | 0.8765 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0596 | 0.4432 |
Echinococcus granulosus | GPCR family 2 | 0.008 | 0.1423 | 0.1622 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0193 | 0.0126 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0837 | 0.0952 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0252 | 0.4863 | 0.6222 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.1102 | 0.7529 |
Echinococcus multilocularis | tar DNA binding protein | 0.0201 | 0.3846 | 0.4386 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0416 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.1423 | 0.1784 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0837 | 0.072 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.008 | 0.1423 | 0.1314 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0017 | 0.018 | 0.042 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0193 | 0.0176 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0017 | 0.018 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0125 | 0.0087 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0267 | 0.5159 | 0.5884 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.3846 | 0.4952 |
Toxoplasma gondii | ABC1 family protein | 0.008 | 0.1423 | 1 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0017 | 0.018 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.008 | 0.1423 | 0.1622 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.1423 | 0.2317 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Onchocerca volvulus | 0.008 | 0.1423 | 0.64 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0596 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0918 | 0.1123 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.018 | 0.0158 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.6868 | 0.8904 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.008 | 0.1423 | 0.1314 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0193 | 0.0526 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.1423 | 0.2317 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0596 | 0.4432 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.1199 | 0.1366 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0267 | 0.5159 | 0.5884 |
Schistosoma mansoni | hypothetical protein | 0.0395 | 0.7707 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0017 | 0.018 | 0.042 |
Echinococcus granulosus | dnaJ subfamily B | 0.0395 | 0.7707 | 0.8792 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0576 | 0.3474 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0037 | 0.0576 | 0.3188 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.3846 | 0.4952 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0823 | 0.1053 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0837 | 0.107 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.1423 | 0.1784 |
Echinococcus granulosus | geminin | 0.0353 | 0.6868 | 0.7835 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0294 | 0.0376 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.0294 | 0.0376 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0294 | 0.0376 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0059 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0226 | 0.4336 | 0.5548 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.008 | 0.1423 | 0.182 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.008 | 0.1423 | 0.2317 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0193 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0128 | 0.238 | 0.2284 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0059 | 0.0075 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0059 | 0.0065 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0115 | 0.213 | 0.2725 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0037 | 0.0576 | 0.3474 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0059 | 0.0075 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0201 | 0.3846 | 0.4921 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0059 | 0.0075 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0193 | 0.0111 |
Trichomonas vaginalis | glutaminase, putative | 0.0287 | 0.5545 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.008 | 0.1423 | 0.1314 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.008 | 0.1423 | 0.1821 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0059 | 0.0065 |
Loa Loa (eye worm) | glutaminase | 0.0287 | 0.5545 | 0.7094 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0059 | 0.0075 |
Echinococcus multilocularis | geminin | 0.0353 | 0.6868 | 0.7835 |
Echinococcus granulosus | neuropeptide s receptor | 0.0448 | 0.8765 | 1 |
Brugia malayi | beta-lactamase family protein | 0.008 | 0.1423 | 0.182 |
Brugia malayi | follicle stimulating hormone receptor | 0.0226 | 0.4336 | 0.5548 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.6868 | 0.8904 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.018 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1423 | 0.1821 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0401 | 0.7816 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.3846 | 0.4952 |
Brugia malayi | beta-lactamase family protein | 0.008 | 0.1423 | 0.182 |
Onchocerca volvulus | Huntingtin homolog | 0.0118 | 0.219 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0193 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0059 | 0.0075 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.