Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin | 0.0025 | 0.018 | 0.0287 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0199 | 0.2649 | 0.3683 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0054 | 0.0596 | 0.0802 |
Onchocerca volvulus | Dual oxidase homolog | 0.0066 | 0.0772 | 0.4984 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0056 | 0.0626 | 0.1725 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0079 | 0.0951 | 0.2571 |
Schistosoma mansoni | peptidyl-glycine monooxygenase | 0.0235 | 0.3155 | 0.4393 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0687 | 0.093 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0312 | 0.0859 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0061 | 0.0691 | 0.1103 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0028 | 0.0228 | 0.0579 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0267 | 0.3619 | 0.9968 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0035 | 0.0331 | 0.0852 |
Brugia malayi | Inositol-1 | 0.0035 | 0.0331 | 0.0866 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0026 | 0.0199 | 0.0317 |
Entamoeba histolytica | hypothetical protein | 0.0079 | 0.0951 | 0.2142 |
Echinococcus multilocularis | protein dispatched 1 | 0.0153 | 0.2 | 0.2 |
Schistosoma mansoni | phd/f-box containing protein | 0.0034 | 0.0312 | 0.0404 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.018 | 0.0496 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0148 | 0.1925 | 0.1925 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0113 | 0.0125 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0096 | 0.1194 | 0.3254 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.3578 | 0.9856 |
Entamoeba histolytica | hypothetical protein | 0.0065 | 0.0747 | 0.1648 |
Loa Loa (eye worm) | RNA binding protein | 0.0056 | 0.0626 | 0.1725 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0029 | 0.0247 | 0.0632 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein | 0.0063 | 0.0728 | 0.1963 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0626 | 0.0845 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0038 | 0.0364 | 0.0944 |
Schistosoma mansoni | ap endonuclease | 0.0017 | 0.0068 | 0.0062 |
Brugia malayi | intermediate filament protein | 0.0025 | 0.018 | 0.0447 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0268 | 0.363 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0148 | 0.1925 | 1 |
Echinococcus multilocularis | lamin | 0.0025 | 0.018 | 0.018 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0125 | 0.1597 | 0.437 |
Onchocerca volvulus | 0.0066 | 0.0772 | 0.4984 | |
Brugia malayi | mbt repeat family protein | 0.0084 | 0.1028 | 0.2796 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0087 | 0.1066 | 0.2422 |
Echinococcus multilocularis | expressed conserved protein | 0.0082 | 0.0992 | 0.0992 |
Echinococcus granulosus | disco interacting protein 2 | 0.0034 | 0.0315 | 0.0503 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0061 | 0.0691 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0315 | 0.0868 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0084 | 0.1028 | 0.1028 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0265 | 0.3578 | 0.3578 |
Brugia malayi | Flap endonuclease-1 | 0.0046 | 0.0485 | 0.1292 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0038 | 0.0364 | 0.0944 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0098 | 0.0156 |
Brugia malayi | Cytochrome P450 family protein | 0.0021 | 0.0131 | 0.031 |
Echinococcus multilocularis | protein tyrosine kinase | 0.0224 | 0.3001 | 0.3001 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0096 | 0.1194 | 0.1194 |
Loa Loa (eye worm) | inositol-1 | 0.0035 | 0.0331 | 0.0912 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0279 | 0.5 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0.003 | 0.0017 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0772 | 0.2087 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0034 | 0.0312 | 0.0497 |
Schistosoma mansoni | jumonji domain containing protein | 0.0034 | 0.0312 | 0.0404 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0046 | 0.0485 | 0.1279 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0719 | 0.198 |
Brugia malayi | isocitrate dehydrogenase | 0.0014 | 0.003 | 0.0032 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0066 | 0.0772 | 0.2127 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0014 | 0.003 | 0.003 |
Echinococcus granulosus | cpg binding protein | 0.0058 | 0.0657 | 0.1048 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0148 | 0.0408 |
Loa Loa (eye worm) | MBCTL1 | 0.0096 | 0.1194 | 0.3288 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0141 | 0.1827 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0096 | 0.1194 | 0.1641 |
Echinococcus granulosus | intermediate filament protein | 0.0025 | 0.018 | 0.0287 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0025 | 0.018 | 0.0496 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0061 | 0.0691 | 0.7663 |
Echinococcus multilocularis | dual specificity | 0.0079 | 0.0951 | 0.0951 |
Echinococcus multilocularis | transcription factor eb | 0.0096 | 0.1185 | 0.1185 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0014 | 0.003 | 0.0083 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0022 | 0.0148 | 0.1367 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0014 | 0.003 | 0.0017 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0014 | 0.003 | 0.003 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0021 | 0.0135 | 0.0156 |
Onchocerca volvulus | Alhambra homolog | 0.0061 | 0.0691 | 0.4303 |
Onchocerca volvulus | Huntingtin homolog | 0.0109 | 0.1368 | 1 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0088 | 0.1072 | 0.2436 |
Brugia malayi | TAR-binding protein | 0.0056 | 0.0626 | 0.1683 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0034 | 0.0312 | 0.0312 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0025 | 0.018 | 0.0447 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.013 | 0.1675 | 0.4615 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.002 | 0.0113 | 0.0959 |
Brugia malayi | Peroxidasin | 0.0066 | 0.0772 | 0.2087 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0129 | 0.1654 | 0.2287 |
Schistosoma mansoni | hypothetical protein | 0.0517 | 0.7151 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0017 | 0.0068 | 0.0187 |
Echinococcus granulosus | DNA methyltransferase 2, putative | 0.0017 | 0.008 | 0.0127 |
Onchocerca volvulus | Peroxidasin homolog | 0.0066 | 0.0772 | 0.4984 |
Echinococcus granulosus | jumonji domain containing protein | 0.0084 | 0.1028 | 0.164 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0129 | 0.1654 | 0.4556 |
Entamoeba histolytica | protein kinase, putative | 0.0079 | 0.0951 | 0.2142 |
Echinococcus multilocularis | peptidyl glycine alpha amidating monooxygenase | 0.0235 | 0.3155 | 0.3155 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0209 | 0.2797 | 0.2797 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0015 | 0.0046 | 0.0073 |
Brugia malayi | RNA binding protein | 0.0056 | 0.0626 | 0.1683 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0084 | 0.1028 | 0.1028 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1082 | 0.2981 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1507 | 0.4153 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0035 | 0.0331 | 0.0739 |
Brugia malayi | jmjC domain containing protein | 0.0252 | 0.3405 | 0.9377 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0068 | 0.0122 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0691 | 0.0936 |
Plasmodium vivax | JmjC domain containing protein | 0.0034 | 0.0312 | 0.426 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0035 | 0.0331 | 0.1418 |
Schistosoma mansoni | inositol monophosphatase | 0.0035 | 0.0331 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1194 | 0.3288 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0054 | 0.06 | 0.1493 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0065 | 0.0747 | 0.0747 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0148 | 0.1925 | 0.3072 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0026 | 0.0202 | 0.025 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0035 | 0.0331 | 0.1418 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0066 | 0.0772 | 0.2127 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0037 | 0.0356 | 0.0568 |
Onchocerca volvulus | Peroxidase homolog | 0.0066 | 0.0772 | 0.4984 |
Brugia malayi | Blistered cuticle protein 3 | 0.0066 | 0.0772 | 0.2087 |
Echinococcus multilocularis | peregrin | 0.0063 | 0.0721 | 0.0721 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0087 | 0.1066 | 0.2901 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0021 | 0.0131 | 0.036 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0691 | 0.1904 |
Brugia malayi | AF-10 protein | 0.002 | 0.0113 | 0.0261 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.003 | 0.0048 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0034 | 0.0312 | 0.3264 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0016 | 0.0054 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1368 | 0.3769 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0079 | 0.0951 | 0.2142 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0084 | 0.1028 | 0.2832 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0657 | 0.0888 |
Onchocerca volvulus | Peroxidase homolog | 0.0066 | 0.0772 | 0.4984 |
Echinococcus multilocularis | cpg binding protein | 0.0058 | 0.0657 | 0.0657 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0015 | 0.0046 | 0.0031 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0054 | 0.06 | 0.1597 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0228 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.2797 | 0.7704 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0127 | 0.1624 | 0.4437 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0268 | 0.363 | 1 |
Onchocerca volvulus | 0.0066 | 0.0772 | 0.4984 | |
Brugia malayi | CHE-14 protein | 0.0148 | 0.1925 | 0.528 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0129 | 0.1654 | 0.2287 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0017 | 0.0068 | 0.0437 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0034 | 0.0312 | 0.3264 |
Brugia malayi | Animal haem peroxidase family protein | 0.0066 | 0.0772 | 0.2087 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0018 | 0.0091 | 0.025 |
Onchocerca volvulus | Peroxidasin homolog | 0.0066 | 0.0772 | 0.4984 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.002 | 0.0113 | 0.0247 |
Echinococcus granulosus | tar DNA binding protein | 0.0056 | 0.0626 | 0.0999 |
Brugia malayi | Cytochrome P450 family protein | 0.0021 | 0.0131 | 0.031 |
Brugia malayi | Muscleblind-like protein | 0.0265 | 0.3578 | 0.9855 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0098 | 0.0104 |
Echinococcus multilocularis | tar DNA binding protein | 0.0056 | 0.0626 | 0.0626 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0079 | 0.0951 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0687 | 0.1891 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0087 | 0.1066 | 0.1701 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0084 | 0.1028 | 0.1409 |
Schistosoma mansoni | lamin | 0.0025 | 0.018 | 0.0219 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0079 | 0.0951 | 0.2571 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0021 | 0.0131 | 0.036 |
Echinococcus multilocularis | protein patched | 0.0148 | 0.1925 | 0.1925 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0235 | 0.316 | 0.5041 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0017 | 0.0068 | 0.0137 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.003 | 0.003 |
Brugia malayi | PHD-finger family protein | 0.0023 | 0.0157 | 0.0385 |
Schistosoma mansoni | DNA (cytosine-5)-methyltransferase | 0.0017 | 0.008 | 0.0078 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0046 | 0.0485 | 0.0485 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0148 | 0.1925 | 0.5304 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.005 | 0.0544 | 0.5955 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0026 | 0.0199 | 0.0199 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0043 | 0.0437 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0481 | 0.1325 |
Echinococcus granulosus | peptidyl glycine alpha amidating monooxygenase | 0.0235 | 0.3155 | 0.5033 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0148 | 0.1925 | 0.3072 |
Brugia malayi | Animal haem peroxidase family protein | 0.0066 | 0.0772 | 0.2087 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0312 | 0.0859 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0014 | 0.003 | 0.0009 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.0019 | 0.0096 | 0.0365 |
Entamoeba histolytica | hypothetical protein | 0.0065 | 0.0747 | 0.1648 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0312 | 0.0859 |
Brugia malayi | Animal haem peroxidase family protein | 0.0066 | 0.0772 | 0.2087 |
Schistosoma mansoni | disco-interacting protein 2 (dip2) | 0.0034 | 0.0315 | 0.0408 |
Echinococcus granulosus | peregrin | 0.0063 | 0.0721 | 0.115 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0035 | 0.0331 | 1 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0061 | 0.0701 | 0.189 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0066 | 0.0772 | 0.2127 |
Brugia malayi | Bromodomain containing protein | 0.0063 | 0.0721 | 0.1945 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0021 | 0.0131 | 0.0296 |
Echinococcus multilocularis | DNA methyltransferase 2, putative | 0.0017 | 0.008 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0228 | 0.0286 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0016 | 0.0054 | 0.0042 |
Echinococcus granulosus | GPCR family 2 | 0.0028 | 0.0228 | 0.0363 |
Echinococcus granulosus | flap endonuclease 1 | 0.0046 | 0.0485 | 0.0774 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0267 | 0.3619 | 0.9968 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0034 | 0.0312 | 0.0497 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0088 | 0.1082 | 0.2945 |
Brugia malayi | jmjC domain containing protein | 0.013 | 0.1675 | 0.4588 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0945 | 0.2604 |
Echinococcus granulosus | dual specificity | 0.0079 | 0.0951 | 0.1518 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0046 | 0.0485 | 0.1279 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0054 | 0.0601 | 0.0601 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0028 | 0.0228 | 0.0363 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0065 | 0.0747 | 0.1015 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0148 | 0.0359 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0084 | 0.1028 | 0.1028 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0046 | 0.0485 | 0.5273 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0084 | 0.1028 | 0.7139 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0312 | 0.0812 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0032 | 0.0283 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Echinococcus granulosus | peroxidasin | 0.0066 | 0.0772 | 0.1232 |
Loa Loa (eye worm) | TAR-binding protein | 0.0056 | 0.0626 | 0.1725 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0129 | 0.1654 | 0.2639 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0343 | 0.0447 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0046 | 0.0485 | 0.1012 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0028 | 0.0228 | 0.0363 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0312 | 0.0812 |
Mycobacterium ulcerans | hypothetical protein | 0.0141 | 0.1827 | 0.4937 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0061 | 0.0691 | 0.0936 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0054 | 0.06 | 0.0808 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0046 | 0.0481 | 0.1267 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0034 | 0.0312 | 0.0312 |
Entamoeba histolytica | DNA (cytosine-5)-methyltransferase, putative | 0.0017 | 0.008 | 0.0029 |
Entamoeba histolytica | Flap nuclease, putative | 0.0046 | 0.0485 | 0.1012 |
Trypanosoma brucei | cytochrome P450, putative | 0.0021 | 0.0131 | 0.0296 |
Onchocerca volvulus | Huntingtin homolog | 0.0109 | 0.1368 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0065 | 0.0747 | 0.1648 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0228 | 0.0286 |
Entamoeba histolytica | hypothetical protein | 0.0088 | 0.1072 | 0.2436 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0084 | 0.1028 | 0.164 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0336 | 0.4593 | 0.7328 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0021 | 0.0135 | 0.1213 |
Echinococcus granulosus | geminin | 0.0455 | 0.6268 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.003 | 0.003 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0032 | 0.029 | 0.0798 |
Plasmodium falciparum | DNA (cytosine-5)-methyltransferase | 0.0017 | 0.008 | 0.0574 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0657 | 0.0888 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0312 | 0.0859 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0.003 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0343 | 0.0447 |
Brugia malayi | Isocitrate dehydrogenase | 0.0014 | 0.003 | 0.0032 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0035 | 0.0331 | 0.3489 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0066 | 0.0772 | 0.2127 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0079 | 0.0951 | 0.262 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0252 | 0.3405 | 0.5433 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0034 | 0.0312 | 0.3264 |
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.0019 | 0.0096 | 0.0078 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.002 | 0.0113 | 0.0247 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0084 | 0.1028 | 0.1409 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0022 | 0.0148 | 0.0344 |
Schistosoma mansoni | peroxidasin | 0.0066 | 0.0772 | 0.105 |
Schistosoma mansoni | protein phosphatase 2C | 0.0034 | 0.0312 | 0.0404 |
Onchocerca volvulus | 0.0034 | 0.0315 | 0.1136 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0312 | 0.0859 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0235 | 0.3155 | 0.8683 |
Brugia malayi | Cytochrome P450 family protein | 0.0032 | 0.029 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0228 | 0.0627 |
Onchocerca volvulus | 0.0084 | 0.1028 | 0.7139 | |
Trypanosoma cruzi | cytochrome P450, putative | 0.0021 | 0.0131 | 0.0296 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0054 | 0.06 | 0.161 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0945 | 0.2604 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0035 | 0.0331 | 0.0331 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0021 | 0.0135 | 0.0216 |
Plasmodium vivax | DNA (cytosine-5)-methyltransferase, putative | 0.0017 | 0.008 | 0.0749 |
Onchocerca volvulus | 0.0066 | 0.0772 | 0.4984 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0028 | 0.0228 | 0.0228 |
Leishmania major | hypothetical protein, conserved | 0.0022 | 0.0148 | 0.0344 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0066 | 0.0772 | 0.4984 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0127 | 0.1624 | 0.4437 |
Brugia malayi | Disco-interacting protein 2 homolog | 0.0034 | 0.0315 | 0.0821 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0129 | 0.1654 | 0.2287 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0035 | 0.0331 | 0.0852 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0.003 | 0.0017 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0165 | 0.0406 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0096 | 0.1194 | 0.1194 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0016 | 0.0054 | 0.0054 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0046 | 0.0485 | 0.2246 |
Echinococcus granulosus | protein tyrosine kinase | 0.0224 | 0.3001 | 0.4788 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0387 | 0.1067 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0028 | 0.0228 | 0.0579 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.002 | 0.0113 | 0.0959 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0126 | 0.1614 | 0.375 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.013 | 0.1675 | 0.2673 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0026 | 0.0199 | 0.0199 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0096 | 0.1194 | 0.1905 |
Schistosoma mansoni | ap endonuclease | 0.0017 | 0.0068 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0228 | 0.0286 |
Brugia malayi | Animal haem peroxidase family protein | 0.0066 | 0.0772 | 0.2087 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0019 | 0.0096 | 0.5 |
Echinococcus multilocularis | disco interacting protein 2 | 0.0034 | 0.0315 | 0.0315 |
Toxoplasma gondii | DNA methyltransferase 2, putative | 0.0017 | 0.008 | 0.0574 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1028 | 0.2832 |
Plasmodium vivax | hypothetical protein, conserved | 0.0061 | 0.0691 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0212 | 0.2827 | 0.3932 |
Echinococcus multilocularis | peroxidasin | 0.0066 | 0.0772 | 0.0772 |
Echinococcus multilocularis | geminin | 0.0455 | 0.6268 | 0.6268 |
Brugia malayi | Bromodomain containing protein | 0.0068 | 0.0793 | 0.2145 |
Brugia malayi | Helix-loop-helix DNA-binding domain containing protein | 0.0096 | 0.1185 | 0.3231 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0096 | 0.1194 | 0.1905 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0035 | 0.0331 | 0.1418 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0028 | 0.0228 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1368 | 0.3769 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0088 | 0.1082 | 0.2981 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0125 | 0.1606 | 0.4424 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.0443 | 0.4782 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0343 | 0.0945 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0046 | 0.0485 | 0.6881 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0268 | 0.363 | 1 |
Echinococcus granulosus | phd:f box containing protein | 0.0034 | 0.0312 | 0.0497 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0054 | 0.06 | 0.3171 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0268 | 0.363 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0014 | 0.003 | 0.0017 |
Plasmodium falciparum | flap endonuclease 1 | 0.0046 | 0.0485 | 0.5273 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0016 | 0.0054 | 0.0086 |
Chlamydia trachomatis | glutamine binding protein | 0.0019 | 0.0096 | 0.5 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0126 | 0.1614 | 0.8323 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0032 | 0.0283 | 0.0451 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0046 | 0.0485 | 0.1279 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0034 | 0.0312 | 0.0404 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0079 | 0.0951 | 0.1301 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0068 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1179 | 0.3247 |
Brugia malayi | Animal haem peroxidase family protein | 0.0066 | 0.0772 | 0.2087 |
Onchocerca volvulus | 0.0043 | 0.0437 | 0.2161 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0157 | 0.0434 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0079 | 0.0951 | 0.2571 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0034 | 0.0312 | 0.0798 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0055 | 0.0612 | 0.1686 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0016 | 0.0054 | 0.0148 |
Schistosoma mansoni | peptidylglycine monooxygenase | 0.0125 | 0.1597 | 0.2207 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0017 | 0.0068 | 0.0122 |
Entamoeba histolytica | protein kinase, putative | 0.0079 | 0.0951 | 0.2142 |
Schistosoma mansoni | cpg binding protein | 0.0055 | 0.0612 | 0.0825 |
Brugia malayi | PHD-finger family protein | 0.0061 | 0.0691 | 0.1863 |
Brugia malayi | hypothetical protein | 0.0209 | 0.2797 | 0.7692 |
Schistosoma mansoni | flap endonuclease-1 | 0.0042 | 0.0422 | 0.0559 |
Schistosoma mansoni | survival motor neuron protein | 0.0043 | 0.0437 | 0.0579 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0037 | 0.0356 | 0.0356 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0061 | 0.0691 | 0.7663 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0021 | 0.0131 | 0.0176 |
Trypanosoma brucei | cytosine-specific DNA methylase, putative | 0.0017 | 0.008 | 0.0155 |
Toxoplasma gondii | hypothetical protein | 0.0075 | 0.0893 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0035 | 0.0331 | 0.0639 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0065 | 0.0747 | 0.1192 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0017 | 0.0068 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.3155 | 0.869 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0015 | 0.0046 | 0.0046 |
Entamoeba histolytica | DNA repair and recombination protein RAD52, putative | 0.0308 | 0.4191 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0084 | 0.1028 | 0.1409 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0437 | 0.0579 |
Schistosoma mansoni | patched 1 | 0.0148 | 0.1925 | 0.2668 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Schistosoma mansoni | peroxidasin | 0.0066 | 0.0772 | 0.105 |
Schistosoma mansoni | tyrosine kinase | 0.0224 | 0.3001 | 0.4177 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0129 | 0.1654 | 0.1654 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0017 | 0.0068 | 0.0108 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0268 | 0.363 | 0.506 |
Plasmodium falciparum | phd finger protein, putative | 0.0061 | 0.0691 | 0.7663 |
Giardia lamblia | PHD finger protein 15 | 0.0061 | 0.0691 | 0.1512 |
Onchocerca volvulus | 0.0055 | 0.0612 | 0.3638 | |
Schistosoma mansoni | inositol monophosphatase | 0.0035 | 0.0331 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0313 | 0.0863 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0091 | 0.0094 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0028 | 0.0228 | 0.0228 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0034 | 0.0312 | 0.0312 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0343 | 0.0447 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0061 | 0.0691 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1066 | 0.2938 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.3578 | 0.9856 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0129 | 0.1654 | 0.2639 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0126 | 0.1614 | 0.8323 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0626 | 0.0845 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0209 | 0.2797 | 0.4462 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0035 | 0.0331 | 0.0528 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0035 | 0.0331 | 0.0852 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0038 | 0.0364 | 0.0944 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0747 | 0.1015 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.013 | 0.1675 | 0.2317 |
Echinococcus multilocularis | phd:f box containing protein | 0.0034 | 0.0312 | 0.0312 |
Brugia malayi | Protein kinase domain containing protein | 0.0227 | 0.3039 | 0.8362 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0626 | 0.0845 |
Leishmania major | modification methylase-like protein | 0.0017 | 0.008 | 0.0155 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0268 | 0.363 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.013 | 0.1675 | 0.2317 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0084 | 0.1028 | 0.164 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0013 | 0.0018 | 0.0051 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0268 | 0.363 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0038 | 0.0364 | 0.0944 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0017 | 0.0068 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.363 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0025 | 0.018 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0343 | 0.0447 |
Echinococcus granulosus | muscleblind protein | 0.0265 | 0.3578 | 0.5709 |
Schistosoma mansoni | dopamine-beta-monooxygenase | 0.0125 | 0.1597 | 0.2207 |
Schistosoma mansoni | hypothetical protein | 0.0455 | 0.6268 | 0.8761 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0022 | 0.0148 | 0.1367 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0268 | 0.363 | 0.5792 |
Toxoplasma gondii | exonuclease III APE | 0.0017 | 0.0068 | 0.0437 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0626 | 0.0845 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1597 | 0.4399 |
Brugia malayi | Bromodomain containing protein | 0.0034 | 0.0312 | 0.0814 |
Echinococcus granulosus | lamin dm0 | 0.0025 | 0.018 | 0.0287 |
Schistosoma mansoni | hypothetical protein | 0.0455 | 0.6268 | 0.8761 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0017 | 0.0068 | 0.021 |
Loa Loa (eye worm) | TK/FAK protein kinase | 0.0227 | 0.3039 | 0.837 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0034 | 0.0312 | 0.0404 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1925 | 0.5304 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0087 | 0.1066 | 0.1066 |
Schistosoma mansoni | bromodomain containing protein | 0.0058 | 0.0646 | 0.0873 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0312 | 0.0798 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0019 | 0.0096 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0054 | 0.0148 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0129 | 0.1654 | 0.4528 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0022 | 0.0148 | 0.1784 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.006 | 0.0687 | 0.185 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0066 | 0.0772 | 0.2127 |
Echinococcus multilocularis | muscleblind protein | 0.0265 | 0.3578 | 0.3578 |
Echinococcus granulosus | expressed conserved protein | 0.0082 | 0.0992 | 0.1582 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0252 | 0.3405 | 0.3405 |
Echinococcus multilocularis | lamin dm0 | 0.0025 | 0.018 | 0.018 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0126 | 0.1614 | 0.8323 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0017 | 0.0068 | 0.0068 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0135 | 0.1584 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0747 | 0.2018 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0022 | 0.0148 | 0.0344 |
Toxoplasma gondii | C-5 cytosine-specific DNA methylase superfamily protein | 0.0017 | 0.008 | 0.0574 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0036 | 0.0049 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0075 | 0.0893 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0054 | 0.0601 | 0.0959 |
Loa Loa (eye worm) | helix-loop-helix DNA-binding domain-containing protein | 0.0095 | 0.1179 | 0.3247 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0098 | 0.0098 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0056 | 0.0626 | 0.1683 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0028 | 0.0228 | 0.0228 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0279 | 0.1385 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0022 | 0.0148 | 0.0344 |
Brugia malayi | CXXC zinc finger family protein | 0.0055 | 0.0612 | 0.1644 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0312 | 0.0812 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0312 | 0.0812 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0267 | 0.3619 | 0.9968 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0235 | 0.316 | 0.316 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0046 | 0.0485 | 0.1336 |
Loa Loa (eye worm) | intermediate filament protein | 0.0025 | 0.018 | 0.0496 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0054 | 0.06 | 0.0957 |
Brugia malayi | hypothetical protein | 0.0109 | 0.1368 | 0.3737 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0015 | 0.0046 | 0.0031 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0127 | 0.1631 | 0.1631 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0054 | 0.06 | 0.1493 |
Echinococcus multilocularis | musashi | 0.0025 | 0.018 | 0.018 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0127 | 0.1624 | 0.4437 |
Schistosoma mansoni | lamin | 0.0025 | 0.018 | 0.0219 |
Echinococcus granulosus | transcription factor eb | 0.0096 | 0.1185 | 0.1891 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0174 | 0.0478 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0035 | 0.0331 | 0.0852 |
Brugia malayi | Protein kinase domain containing protein | 0.0079 | 0.0951 | 0.2582 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0047 | 0.0503 | 0.1386 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0021 | 0.0131 | 0.036 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0019 | 0.0096 | 1 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0268 | 0.363 | 0.363 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0626 | 0.0845 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0129 | 0.1654 | 0.1654 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0088 | 0.1082 | 0.2945 |
Leishmania major | cytochrome p450-like protein | 0.0021 | 0.0131 | 0.0296 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0022 | 0.0148 | 0.1367 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0267 | 0.3619 | 0.9968 |
Brugia malayi | mbt repeat family protein | 0.0084 | 0.1028 | 0.2796 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0021 | 0.0135 | 0.0135 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0034 | 0.0312 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0034 | 0.0312 | 0.0798 |
Giardia lamblia | DNA repair protein RAD52 | 0.0308 | 0.4191 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0336 | 0.4593 | 0.4593 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0054 | 0.06 | 0.06 |
Entamoeba histolytica | hypothetical protein | 0.0065 | 0.0747 | 0.1648 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0034 | 0.0312 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0772 | 0.2127 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 1230 nM | Concentration causing maximal effect on [Ca2+] release from the intracellular stores of permealized hepatocytes | ChEMBL. | 11405648 |
EC50 (functional) | = 1650 nM | Concentration causing maximal effect on [Ca2+] release from the intracellular stores of permealized hepatocytes | ChEMBL. | 11405648 |
Hill coefficient (binding) | = 1.01 | Hill coefficient, measured using equilibrium competition binding with [3H]-Inositol(1,4,5)P3 | ChEMBL. | 11405648 |
Hill coefficient (binding) | = 1.12 | Hill coefficient, measured using equilibrium competition binding with [3H]-Inositol(1,4,5)P3 | ChEMBL. | 11405648 |
Hill coefficient (binding) | = 2.61 | Hill coefficient for the effect on [Ca2+] release from the intracellular stores of permealized hepatocytes | ChEMBL. | 11405648 |
Hill coefficient (binding) | = 2.9 | Hill coefficient for the effect on [Ca2+] release from the intracellular stores of permealized hepatocytes | ChEMBL. | 11405648 |
Kd (binding) | = 62 nM | Binding affinity towards rat liver membrane, measured using equilibrium competition binding with [3H]-Inositol(1,4,5)P3 | ChEMBL. | 11405648 |
Kd (binding) | = 98 nM | Binding affinity towards rat liver membrane, measured using equilibrium competition binding with [3H]-Inositol(1,4,5)P3 | ChEMBL. | 11405648 |
Max response (functional) | = 59 % | Fraction of total [Ca2+] stores released by a maximal concentration of the compound | ChEMBL. | 11405648 |
Ratio (binding) | = -21 | Ratio to Ins(1,4,5)P3 was measured(ratio greater than 1 denotes greater affinity and less than -1 denotes lesser affinity) | ChEMBL. | 11405648 |
Ratio (functional) | = -18 | Ratio to Ins(1,4,5)P3, for the effect on [Ca2+] release from the intracellular stores of permealized hepatocytes(ratio greater than 1 denotes greater potency and less than -1 denotes lesser potency) | ChEMBL. | 11405648 |
Ratio (binding) | = -14 | Ratio to Ins(1,4,5)P3 was measured(ratio greater than 1 denotes greater affinity and less than -1 denotes lesser affinity) | ChEMBL. | 11405648 |
Ratio (functional) | = -14 | Ratio to Ins(1,4,5)P3, for the effect on [Ca2+] release from the intracellular stores of permealized hepatocytes(ratio greater than 1 denotes greater potency and less than -1 denotes lesser potency) | ChEMBL. | 11405648 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.