Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.292 | 0.0969 |
Echinococcus multilocularis | chromobox protein 1 | 0.0081 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0074 | 0.838 | 0.7934 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.838 | 0.7934 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0081 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0081 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.216 | 0.216 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0049 | 0.292 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0081 | 1 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0081 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.0081 | 1 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0046 | 0.216 | 0.7399 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.292 | 0.0969 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.838 | 0.838 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.838 | 0.7934 |
Schistosoma mansoni | chromobox protein | 0.0081 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.838 | 0.838 |
Echinococcus multilocularis | chromobox protein 1 | 0.0081 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0081 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.838 | 0.838 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.