Detailed information for compound 1085070

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 535.58 | Formula: C29H24F3N3O2S
  • H donors: 2 H acceptors: 3 LogP: 5.76 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: FC(c1ccc2c(c1)nc([nH]2)c1cccc(c1)c1cccc(c1)CNCc1ccc(cc1)S(=O)(=O)C)(F)F
  • InChi: 1S/C29H24F3N3O2S/c1-38(36,37)25-11-8-19(9-12-25)17-33-18-20-4-2-5-21(14-20)22-6-3-7-23(15-22)28-34-26-13-10-24(29(30,31)32)16-27(26)35-28/h2-16,33H,17-18H2,1H3,(H,34,35)
  • InChiKey: BVSWRDJFHGJWQP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0042 0.0068 0.0068
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0643 0.456 0.645
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.137 1 1
Entamoeba histolytica vacuolar protein sorting 26 0.0145 0.0839 0.5
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0066 0.0066
Schistosoma mansoni chromobox protein 0.0075 0.0315 0.0289
Trichomonas vaginalis transmembrane protein nessy, putative 0.0145 0.0839 0.1107
Echinococcus granulosus Niemann Pick C1 protein 0.0564 0.3971 0.3955
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0092 0.0034
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0446 0.0438
Schistosoma mansoni smad1 5 8 and 0.0042 0.0066 0.0039
Loa Loa (eye worm) hypothetical protein 0.0082 0.0363 0.0363
Echinococcus multilocularis Smad4 0.0042 0.0066 0.0057
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0047 0.0021
Echinococcus granulosus chromobox protein 1 0.0075 0.0315 0.0289
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0145 0.0839 0.0831
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.05 0.0475
Echinococcus multilocularis smad 0.0042 0.0066 0.0057
Echinococcus granulosus o acyltransferase membrane bound domain 0.0145 0.0839 0.0814
Schistosoma mansoni zinc finger protein 0.0145 0.0839 0.0814
Trichomonas vaginalis conserved hypothetical protein 0.0564 0.3971 0.5605
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0145 0.0839 0.0839
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0636 0.0611
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0564 0.3971 0.3971
Loa Loa (eye worm) hypothetical protein 0.137 1 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.015 0.0874 0.085
Schistosoma mansoni Smad4 0.0042 0.0066 0.0039
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0214 0.0214
Leishmania major glycerol uptake protein, putative 0.0145 0.0839 0.0623
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.05 0.0463
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0316 0.2114 0.2084
Schistosoma mansoni thyroid hormone receptor 0.0148 0.0857 0.0833
Loa Loa (eye worm) hypothetical protein 0.0816 0.5856 0.5856
Echinococcus multilocularis chromobox protein 1 0.0075 0.0315 0.0307
Brugia malayi MBOAT family protein 0.0145 0.0839 0.0804
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.015 0.0874 0.0866
Schistosoma mansoni hypothetical protein 0.0145 0.0839 0.0814
Loa Loa (eye worm) hhat protein 0.0145 0.0839 0.0839
Brugia malayi Bromodomain containing protein 0.0313 0.2093 0.2063
Echinococcus granulosus o acyltransferase membrane bound domain 0.0145 0.0839 0.0814
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0214 0.0214
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0145 0.0839 0.0831
Schistosoma mansoni patched 1 0.0564 0.3971 0.3955
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0137 0.0775 0.075
Brugia malayi MBOAT family protein 0.0145 0.0839 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.0145 0.0839 0.1107
Echinococcus multilocularis microtubule associated protein 2 0.0678 0.4826 0.4821
Schistosoma mansoni methyl-cpg binding protein mbd 0.0071 0.0285 0.0259
Loa Loa (eye worm) hypothetical protein 0.0295 0.196 0.196
Brugia malayi Smad1 0.0042 0.0066 0.0027
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0315 0.0315
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.067 0.0645
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0505 0.3527 1
Echinococcus granulosus zinc finger protein 0.0082 0.0364 0.0338
Schistosoma mansoni smad 0.0042 0.0066 0.0039
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0071 0.0285 0.0276
Loa Loa (eye worm) bromodomain containing protein 0.0074 0.0304 0.0304
Brugia malayi latrophilin 2 splice variant baaae 0.0216 0.1367 0.1334
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0194 0.1202 0.1194
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0145 0.0839 0.0831
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0068 0.0097
Brugia malayi Latrophilin receptor protein 2 0.01 0.05 0.0463
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0145 0.0839 0.0814
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0214 0.0187
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0027 0.0018
Schistosoma mansoni zinc finger protein 0.0082 0.0364 0.0338
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0066 0.0039
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0249 0.1616 0.1593
Echinococcus granulosus GPCR family 2 0.01 0.05 0.0475
Brugia malayi Calcitonin receptor-like protein seb-1 0.0316 0.2114 0.2084
Loa Loa (eye worm) MBOAT family protein 0.0145 0.0839 0.0839
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0363 0.0136
Brugia malayi hypothetical protein 0.0082 0.0363 0.0326
Echinococcus granulosus fetal alzheimer antigen falz 0.0094 0.0456 0.0431
Loa Loa (eye worm) transcription factor SMAD2 0.0614 0.4347 0.4347
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0066 0.0066
Loa Loa (eye worm) MBOAT family protein 0.0145 0.0839 0.0839
Entamoeba histolytica hypothetical protein 0.0145 0.0839 0.5
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.137 1 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0446 0.0421
Echinococcus granulosus histone lysine methyltransferase setb 0.0194 0.1202 0.1179
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0643 0.456 0.645
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0363 0.0136
Loa Loa (eye worm) hypothetical protein 0.01 0.05 0.05
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0505 0.3527 0.3521
Trichomonas vaginalis porcupine, putative 0.0145 0.0839 0.1107
Plasmodium vivax SET domain protein, putative 0.0123 0.067 0.097
Loa Loa (eye worm) RNA binding protein 0.0062 0.0214 0.0214
Schistosoma mansoni hypothetical protein 0.01 0.05 0.0475
Loa Loa (eye worm) Smad1 0.0042 0.0066 0.0066
Brugia malayi diacylglycerol acyltransferase 0.0505 0.3527 0.3502
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0069 0.0042
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0066 0.0039
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0145 0.0839 0.0814
Loa Loa (eye worm) hypothetical protein 0.0216 0.1367 0.1367
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0047 0.0038
Schistosoma mansoni chromobox protein 0.0075 0.0315 0.0289
Loa Loa (eye worm) hypothetical protein 0.0145 0.0839 0.0839
Echinococcus multilocularis chromobox protein 1 0.0075 0.0315 0.0307
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0855 0.6149 0.6149
Brugia malayi jmjC domain containing protein 0.0093 0.0446 0.0409
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0194 0.1202 0.1179
Echinococcus granulosus peregrin 0.0038 0.0038 0.0012
Schistosoma mansoni hypothetical protein 0.0086 0.0397 0.0371
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0145 0.0839 0.0814
Onchocerca volvulus 0.0104 0.0531 0.0756
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0214 0.0187
Loa Loa (eye worm) PHD-finger family protein 0.0086 0.0397 0.0397
Echinococcus granulosus sterol O acyltransferase 1 0.0816 0.5856 0.5845
Loa Loa (eye worm) hypothetical protein 0.0194 0.1202 0.1202
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.137 1 0.5
Loa Loa (eye worm) hypothetical protein 0.016 0.095 0.095
Leishmania major glycerol uptake protein, putative 0.0145 0.0839 0.0623
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0145 0.0839 0.0814
Schistosoma mansoni microtubule-associated protein tau 0.0678 0.4826 0.4812
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0145 0.0839 0.0831
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0145 0.0839 0.0814
Trypanosoma cruzi GUP1, putative 0.0145 0.0839 0.0623
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.05 0.0491
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0505 0.3527 1
Echinococcus granulosus sterol regulatory element binding protein 0.0564 0.3971 0.3955
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0505 0.3527 0.3509
Schistosoma mansoni sterol O-acyltransferase 1 0.0816 0.5856 0.5845
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0505 0.3527 0.3527
Schistosoma mansoni hypothetical protein 0.0216 0.1367 0.1344
Trypanosoma cruzi glycerol uptake protein, putative 0.0145 0.0839 0.0623
Echinococcus granulosus tumor protein p63 0.0711 0.5073 0.506
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0643 0.456 0.645
Schistosoma mansoni hypothetical protein 0.01 0.05 0.0475
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0069 0.0042
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0363 0.0136
Schistosoma mansoni hypothetical protein 0.0064 0.023 0.0204
Schistosoma mansoni thyroid hormone receptor 0.0148 0.0857 0.0833
Schistosoma mansoni hypothetical protein 0.0137 0.0775 0.075
Trypanosoma cruzi glycerol uptake protein, putative 0.0145 0.0839 0.0623
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0145 0.0839 0.0831
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0145 0.0839 0.5
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.067 0.0662
Echinococcus multilocularis zinc finger protein 0.0082 0.0364 0.0355
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0092 0.0034
Leishmania major hypothetical protein, conserved 0.0145 0.0839 0.0623
Brugia malayi chromobox protein homolog 3 0.0042 0.0068 0.003
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.05 0.0491
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0315 0.0355
Schistosoma mansoni smad1 5 8 and 0.0042 0.0066 0.0039
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0505 0.3527 0.3509
Brugia malayi MH2 domain containing protein 0.0042 0.0066 0.0027
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0066 0.0057
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0145 0.0839 0.0831
Leishmania major glycerol uptake protein, putative 0.0145 0.0839 0.0623
Brugia malayi MBOAT family protein 0.0145 0.0839 0.0804
Trypanosoma cruzi GUP1, putative 0.0145 0.0839 0.0623
Onchocerca volvulus 0.0145 0.0839 0.1193
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0214 0.0187
Brugia malayi Pre-SET motif family protein 0.0855 0.6149 0.6134
Loa Loa (eye worm) MH2 domain-containing protein 0.0614 0.4347 0.4347
Leishmania major glycerol uptake protein, putative 0.0145 0.0839 0.0623
Echinococcus multilocularis sterol regulatory element binding protein 0.0564 0.3971 0.3966
Echinococcus granulosus chromobox protein 1 0.0075 0.0315 0.0289
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.067 0.097
Toxoplasma gondii hypothetical protein 0.0145 0.0839 0.1503
Schistosoma mansoni hypothetical protein 0.01 0.05 0.0475
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0564 0.3971 0.3955
Loa Loa (eye worm) hypothetical protein 0.0178 0.1084 0.1084
Brugia malayi MH2 domain containing protein 0.0614 0.4347 0.4325
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0145 0.0839 0.5
Leishmania major glycerol uptake protein, putative 0.0145 0.0839 0.0623
Brugia malayi MH2 domain containing protein 0.0042 0.0066 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0194 0.1202 0.1179
Echinococcus multilocularis thyroid hormone receptor alpha 0.0148 0.0857 0.0849
Schistosoma mansoni methyl-cpg binding protein mbd 0.0071 0.0285 0.0259
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0214 0.0176
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0316 0.2114 0.2114
Brugia malayi MBOAT family protein 0.0145 0.0839 0.0804
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0249 0.1616 0.1608
Brugia malayi RNA binding protein 0.0062 0.0214 0.0176
Loa Loa (eye worm) hhat protein 0.0145 0.0839 0.0839
Loa Loa (eye worm) hypothetical protein 0.0564 0.3971 0.3971
Trypanosoma brucei glycerol uptake protein, putative 0.0145 0.0839 0.0623
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0094 0.0456 0.0431
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0145 0.0839 0.0814
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0135 0.0762 0.0738
Trypanosoma brucei glycerol uptake protein, putative 0.0145 0.0839 0.0623
Brugia malayi Bromodomain containing protein 0.016 0.0948 0.0913
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0066 0.0039
Brugia malayi PHD-finger family protein 0.0104 0.053 0.0494
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0069 0.0042
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.137 1 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0214 0.0187
Echinococcus granulosus Protein patched homolog 1 0.0564 0.3971 0.3955
Trichomonas vaginalis set domain proteins, putative 0.0973 0.7032 1
Echinococcus multilocularis tumor protein p63 0.0711 0.5073 0.5069
Loa Loa (eye worm) hypothetical protein 0.0145 0.0839 0.0839
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0094 0.0456 0.0448
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0531 0.0506
Brugia malayi TAR-binding protein 0.0062 0.0214 0.0176
Brugia malayi MH1 domain containing protein 0.0042 0.0066 0.0027
Echinococcus multilocularis protein patched 0.0564 0.3971 0.3966
Echinococcus granulosus smad 0.0042 0.0066 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0214 0.0187
Echinococcus granulosus Smad4 0.0042 0.0066 0.0039
Treponema pallidum alginate O-acetylation protein (algI) 0.0145 0.0839 0.5
Loa Loa (eye worm) hypothetical protein 0.0359 0.2441 0.2441
Echinococcus multilocularis sterol O acyltransferase 1 0.0816 0.5856 0.5852
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0145 0.0839 0.0814
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0505 0.3527 1
Echinococcus granulosus tar DNA binding protein 0.0062 0.0214 0.0187
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.05 0.05
Loa Loa (eye worm) MBOAT family protein 0.0145 0.0839 0.0839
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0304 0.0278
Brugia malayi CHE-14 protein 0.0564 0.3971 0.3948
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.137 1 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0066 0.0057
Schistosoma mansoni bromodomain containing protein 0.0264 0.1728 0.1706
Brugia malayi Pre-SET motif family protein 0.0123 0.067 0.0634
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0214 0.0205
Brugia malayi hypothetical protein 0.0053 0.0147 0.0109
Echinococcus multilocularis protein dispatched 1 0.0564 0.3971 0.3966
Echinococcus multilocularis peregrin 0.0038 0.0038 0.0029
Brugia malayi jmjC domain containing protein 0.0042 0.0069 0.003
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0145 0.0839 0.0814
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0069 0.0069
Echinococcus multilocularis GPCR, family 2 0.01 0.05 0.0491
Entamoeba histolytica hypothetical protein, conserved 0.0145 0.0839 0.5
Onchocerca volvulus 0.0135 0.0762 0.1084
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0145 0.0839 0.0814
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0505 0.3527 1
Echinococcus granulosus microtubule associated protein 2 0.0678 0.4826 0.4812
Echinococcus multilocularis Niemann Pick C1 protein 0.0564 0.3971 0.3966
Loa Loa (eye worm) hypothetical protein 0.0316 0.2114 0.2114
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.137 1 1
Brugia malayi Hhat protein 0.0145 0.0839 0.0804
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0145 0.0839 0.0831
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0137 0.0775 0.0767
Leishmania major hypothetical protein, conserved 0.0082 0.0363 0.0136
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.137 1 1
Schistosoma mansoni hypothetical protein 0.01 0.05 0.0475
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0092 0.0131
Echinococcus granulosus methyl CpG binding domain protein 2 0.0071 0.0285 0.0259
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.05 0.0475
Brugia malayi MH1 domain containing protein 0.0042 0.0066 0.0027
Schistosoma mansoni zinc finger protein 0.0064 0.023 0.0204
Loa Loa (eye worm) hypothetical protein 0.0104 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.017 0.1024 0.1024
Trichomonas vaginalis conserved hypothetical protein 0.0145 0.0839 0.1107
Brugia malayi Heterochromatin protein 1 0.0075 0.0315 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0145 0.0839 0.1107
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0643 0.456 0.5
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0145 0.0839 0.0839
Echinococcus granulosus o acyltransferase membrane bound domain 0.0145 0.0839 0.0814
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0145 0.0839 0.5
Schistosoma mansoni smad1 5 8 and 0.0042 0.0066 0.0039
Trypanosoma cruzi glycerol uptake protein, putative 0.0145 0.0839 0.0623
Onchocerca volvulus 0.0973 0.7032 1
Brugia malayi MBOAT family protein 0.0145 0.0839 0.0804
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0315 0.0355
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.137 1 1
Loa Loa (eye worm) hypothetical protein 0.0671 0.477 0.477

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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