Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.023 | 0.7852 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0859 | 0.051 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0094 | 0.2955 | 0.5751 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0028 | 0.0583 | 0.0471 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.105 | 0.151 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0859 | 0.0651 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0031 | 0.0716 | 0.0525 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0094 | 0.2955 | 0.3934 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.1489 | 0.1171 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0091 | 0.2864 | 0.5549 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0091 | 0.2847 | 0.3768 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.023 | 0.7852 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.014 | 0.4631 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0413 | 0.0055 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0028 | 0.0583 | 0.0708 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0859 | 0.0651 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.105 | 0.0711 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0031 | 0.0716 | 0.0361 |
Brugia malayi | Thioredoxin reductase | 0.0091 | 0.2847 | 0.3768 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0859 | 0.0651 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0859 | 0.0741 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0207 | 0.7022 | 0.8891 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0207 | 0.7022 | 0.8885 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0094 | 0.2955 | 0.3934 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0641 | 0.028 |
Mycobacterium ulcerans | hypothetical protein | 0.0028 | 0.0583 | 0.0497 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.014 | 0.4631 | 0.5669 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0037 | 0.0914 | 0.0568 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0287 | 0.9912 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0091 | 0.2847 | 1 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0413 | 0.1451 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0091 | 0.2847 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0207 | 0.7022 | 0.8891 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0241 | 0.824 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0241 | 0.824 | 1 |
Schistosoma mansoni | apoptosis regulator bax | 0.0094 | 0.2955 | 0.2683 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0037 | 0.0914 | 0.1109 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.014 | 0.4631 | 0.5693 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0028 | 0.0583 | 0.0497 |
Schistosoma mansoni | eyes absent homolog | 0.01 | 0.3171 | 0.2907 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0031 | 0.0716 | 0.0869 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.2955 | 0.2683 |
Leishmania major | trypanothione reductase | 0.0091 | 0.2847 | 0.3455 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0028 | 0.0583 | 0.0222 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Echinococcus granulosus | expressed protein | 0.0038 | 0.0946 | 0.1277 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0207 | 0.7022 | 0.8891 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0031 | 0.0716 | 0.0358 |
Leishmania major | hypothetical protein, conserved | 0.0241 | 0.824 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0031 | 0.0716 | 0.1247 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0641 | 0.2253 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0413 | 0.0096 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0859 | 0.3017 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0859 | 0.0741 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0107 | 0.3429 | 0.4655 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0094 | 0.2955 | 0.5751 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0128 | 0.0156 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0859 | 0.1143 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0859 | 0.1042 |
Onchocerca volvulus | 0.0035 | 0.0859 | 0.0297 | |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.4864 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0031 | 0.0716 | 0.1247 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0859 | 0.1143 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0413 | 0.0501 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0641 | 0.028 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0107 | 0.3429 | 0.4655 |
Brugia malayi | glutathione reductase | 0.0091 | 0.2847 | 0.3768 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0413 | 0.0096 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0859 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0859 | 0.0741 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.105 | 0.0711 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0859 | 0.1042 |
Trypanosoma brucei | unspecified product | 0.0022 | 0.0372 | 0.0451 |
Trypanosoma brucei | trypanothione reductase | 0.0091 | 0.2847 | 0.3455 |
Trichomonas vaginalis | set domain proteins, putative | 0.0233 | 0.7955 | 0.7949 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0022 | 0.0372 | 0.0451 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0859 | 0.051 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Onchocerca volvulus | 0.0233 | 0.7955 | 1 | |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0413 | 0.5764 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0091 | 0.2847 | 0.3308 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0091 | 0.2847 | 0.3455 |
Brugia malayi | hypothetical protein | 0.0041 | 0.105 | 0.1033 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0128 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.105 | 0.0705 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.2524 | 0.4791 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0859 | 0.1042 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0859 | 0.051 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0107 | 0.3429 | 0.4162 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0031 | 0.0716 | 0.1247 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0031 | 0.0716 | 0.0869 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0031 | 0.0716 | 0.0869 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0859 | 0.0741 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.105 | 0.0711 |
Loa Loa (eye worm) | glutathione reductase | 0.0091 | 0.2847 | 0.3768 |
Brugia malayi | hypothetical protein | 0.01 | 0.3171 | 0.4263 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.3429 | 0.4162 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Schistosoma mansoni | kinase | 0.0054 | 0.154 | 0.1213 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0094 | 0.2955 | 0.5751 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0031 | 0.0716 | 0.0809 |
Toxoplasma gondii | thioredoxin reductase | 0.0091 | 0.2847 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0859 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0859 | 0.0741 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0037 | 0.0914 | 0.1109 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.4864 | 0.684 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0037 | 0.0914 | 0.3209 |
Onchocerca volvulus | 0.0035 | 0.0859 | 0.0297 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0859 | 0.1143 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.6939 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0028 | 0.0583 | 0.0497 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0287 | 0.9912 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.105 | 0.0711 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0859 | 0.051 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.2524 | 0.3277 |
Trypanosoma brucei | RNA helicase, putative | 0.0101 | 0.321 | 0.3896 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0372 | 0.0451 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0031 | 0.0716 | 0.1247 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0603 | 0.0514 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0094 | 0.2955 | 0.2683 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0372 | 0.0451 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0031 | 0.0716 | 0.0361 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0859 | 0.0741 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0031 | 0.0716 | 0.2517 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0128 | 0.0156 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0037 | 0.0914 | 0.1109 |
Trichomonas vaginalis | rotamase, putative | 0.0037 | 0.0914 | 0.0568 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0022 | 0.0372 | 0.0451 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0946 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.3171 | 0.4263 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0859 | 0.0651 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0859 | 0.1143 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0022 | 0.0372 | 0.0451 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.023 | 0.7852 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0031 | 0.0716 | 0.1247 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0031 | 0.0716 | 0.0869 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0031 | 0.0716 | 0.0461 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0641 | 0.06 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0031 | 0.0716 | 0.1247 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0859 | 0.0741 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0859 | 0.0599 |
Leishmania major | DNA polymerase eta, putative | 0.0022 | 0.0372 | 0.0451 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0107 | 0.3429 | 0.6806 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0128 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.4864 | 0.684 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.4864 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0859 | 0.0651 |
Echinococcus multilocularis | expressed protein | 0.0038 | 0.0946 | 0.1277 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0037 | 0.0914 | 0.1109 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0413 | 0.1451 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0859 | 0.0651 |
Mycobacterium tuberculosis | Conserved protein | 0.0028 | 0.0583 | 0.0283 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0207 | 0.7022 | 0.8891 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0859 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0859 | 0.0741 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0028 | 0.0583 | 0.0497 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0094 | 0.2955 | 0.5751 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.2955 | 0.2683 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.023 | 0.7852 | 1 |
Giardia lamblia | Kinase, PLK | 0.0107 | 0.3429 | 0.3205 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0031 | 0.0716 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0107 | 0.3429 | 0.6806 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0859 | 0.0741 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0028 | 0.0583 | 0.0708 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0372 | 0.0451 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0028 | 0.0583 | 0.0497 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0859 | 0.0741 |
Plasmodium falciparum | thioredoxin reductase | 0.0091 | 0.2847 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0859 | 0.0651 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0859 | 0.051 |
Schistosoma mansoni | rotamase | 0.0038 | 0.0946 | 0.0596 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0859 | 0.1832 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0641 | 0.06 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0031 | 0.0716 | 0.0869 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0859 | 0.0741 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0031 | 0.0716 | 0.0767 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0031 | 0.0716 | 0.0869 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Onchocerca volvulus | 0.0082 | 0.2524 | 0.2574 | |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0031 | 0.0716 | 0.0869 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0413 | 0.0043 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0641 | 0.041 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0038 | 0.0946 | 0.0873 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0091 | 0.2864 | 0.5549 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.6939 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0859 | 0.0651 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.4864 | 0.684 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0023 | 0.0417 | 0.0068 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0107 | 0.3429 | 0.3205 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0859 | 0.051 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.9912 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0031 | 0.0716 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0859 | 0.1084 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.2955 | 0.2683 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0031 | 0.0716 | 0.0767 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.2955 | 0.3934 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.3171 | 0.4263 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0641 | 0.028 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.2524 | 0.2235 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0023 | 0.0417 | 0.0068 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0038 | 0.0946 | 0.0873 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0031 | 0.0716 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0641 | 0.041 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0859 | 0.1143 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.105 | 0.151 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.105 | 0.0705 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.321 | 0.2948 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.2524 | 0.4791 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0031 | 0.0716 | 0.0809 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0028 | 0.0583 | 0.0283 |
Treponema pallidum | NADH oxidase | 0.0031 | 0.0716 | 0.032 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0128 | 0.0156 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0031 | 0.0716 | 0.2517 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.3429 | 0.4162 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.1489 | 0.1171 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0859 | 0.0506 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0207 | 0.7022 | 0.8891 |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0641 | 0.06 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.3429 | 0.3175 |
Plasmodium falciparum | glutathione reductase | 0.0091 | 0.2847 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0859 | 0.0599 |
Onchocerca volvulus | 0.0035 | 0.0859 | 0.0297 | |
Trichomonas vaginalis | rotamase, putative | 0.0038 | 0.0946 | 0.0601 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0413 | 0.0501 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0031 | 0.0716 | 0.0361 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0241 | 0.824 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0031 | 0.0716 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0716 | 0.0869 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0207 | 0.7022 | 0.8891 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.2524 | 0.3277 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0028 | 0.0583 | 0.0471 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3429 | 0.3205 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0107 | 0.3429 | 0.3812 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0226 | 0.7713 | 0.9814 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0859 | 0.0651 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0641 | 0.0939 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0859 | 0.0651 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0028 | 0.0583 | 0.0708 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.4864 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0641 | 0.028 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0372 | 0.0451 |
Trypanosoma brucei | polo-like protein kinase | 0.0107 | 0.3429 | 0.4162 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0859 | 0.0741 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.