Detailed information for compound 1087745

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.936 | Formula: C21H22ClN3O2S
  • H donors: 0 H acceptors: 2 LogP: 3.55 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)CC[C@]1(OC[C@H](O1)CSc1ccncc1)Cn1cncc1
  • InChi: 1S/C21H22ClN3O2S/c22-18-3-1-17(2-4-18)5-8-21(15-25-12-11-24-16-25)26-13-19(27-21)14-28-20-6-9-23-10-7-20/h1-4,6-7,9-12,16,19H,5,8,13-15H2/t19-,21+/m0/s1
  • InChiKey: LGWLOZYJBIRIKR-PZJWPPBQSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0133 0.1063
Trypanosoma brucei trypanothione reductase 0.0046 0.0145 0.3065
Brugia malayi nuclear hormone receptor family member odr-7 0.0098 0.0366 0.0867
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0074 0.0144
Loa Loa (eye worm) hypothetical protein 0.0109 0.0416 0.0956
Onchocerca volvulus 0.0098 0.0366 0.3053
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0207 0.0832 0.197
Schistosoma mansoni microtubule-associated protein tau 0.0674 0.282 0.2808
Echinococcus multilocularis neuropeptide s receptor 0.0478 0.1987 0.1974
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.2154 0.9118 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0098 0.0366 0.0351
Schistosoma mansoni loxhd1 0.0019 0.0032 0.0016
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0018 0.01
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0116 0.0443 1
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0112 0.0427 0.0412
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0282 0.2384
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0207 0.0832 0.0817
Loa Loa (eye worm) intermediate filament protein 0.0063 0.0218 0.0484
Loa Loa (eye worm) hypothetical protein 0.0063 0.0218 0.0484
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0395 0.3431
Loa Loa (eye worm) hypothetical protein 0.0626 0.2617 0.6183
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0041 0.1024
Brugia malayi nuclear receptor NHR-88 0.0207 0.0832 0.197
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0198 0.0438
Schistosoma mansoni hypothetical protein 0.008 0.0292 0.0277
Loa Loa (eye worm) hypothetical protein 0.0109 0.0416 0.0956
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0207 0.0832 0.197
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0032
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0133 0.1043
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0041 0.064
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0207 0.0832 0.0817
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0536 0.0521
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0133 0.4463
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0339 0.0355
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0138 0.0536 0.124
Brugia malayi beta-lactamase 0.0043 0.0133 0.0316
Echinococcus multilocularis RUN 0.0019 0.0032 0.0016
Trichomonas vaginalis set domain proteins, putative 0.0276 0.1126 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0366 0.0351
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.008 0.0292 0.0277
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0207 0.0832 0.1944
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0041 0.0878
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0133 0.1043
Schistosoma mansoni nuclear hormone receptor 0.0207 0.0832 0.0817
Brugia malayi nuclear hormone receptor 0.0098 0.0366 0.0867
Toxoplasma gondii ABC1 family protein 0.0043 0.0133 0.4411
Echinococcus multilocularis voltage dependent calcium channel 0.0112 0.0427 0.0412
Brugia malayi glutathione reductase 0.0046 0.0145 0.0344
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0395 0.3431
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0018 0.01
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0282 0.6253
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0282 0.2384
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0133 0.0316
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0282 0.5996
Echinococcus granulosus ecdysone induced protein 78C 0.0207 0.0832 0.0896
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0133 0.1043
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0098 0.0366 0.0351
Schistosoma mansoni nuclear receptor 0.0098 0.0366 0.0351
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0285
Schistosoma mansoni nuclear receptor nhr-48 0.0098 0.0366 0.0351
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0207 0.0832 0.0896
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0098 0.0366 0.0385
Loa Loa (eye worm) hypothetical protein 0.0109 0.0416 0.0956
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0018 0.016
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0016 0.0058
Onchocerca volvulus 0.0043 0.0133 0.0924
Brugia malayi Inositol-1 0.0078 0.0282 0.0668
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0133 0.1063
Toxoplasma gondii exonuclease III APE 0.0021 0.0041 0.094
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0469 0.1081
Loa Loa (eye worm) hypothetical protein 0.0029 0.0074 0.0144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0339 0.0324
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0207 0.0832 0.0817
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0116 0.0443 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0133 0.279
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0016 0.0006
Mycobacterium tuberculosis Conserved protein 0.0043 0.0133 0.1063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0339 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0207 0.0832 0.197
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0116 0.0443 0.0428
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0145 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0339 0.0324
Echinococcus granulosus tar DNA binding protein 0.0138 0.0536 0.0571
Schistosoma mansoni intermediate filament proteins 0.0063 0.0218 0.0202
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0133 0.0118
Brugia malayi ecdysteroid receptor 0.0207 0.0832 0.197
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0207 0.0832 0.197
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0145 0.3065
Echinococcus multilocularis sodium channel protein 0.0048 0.0153 0.0137
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0133 0.1063
Loa Loa (eye worm) beta-lactamase 0.0043 0.0133 0.0285
Loa Loa (eye worm) nuclear receptor NHR-67 0.0098 0.0366 0.0838
Echinococcus multilocularis voltage dependent calcium channel 0.0112 0.0427 0.0412
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0444 1
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0133 0.1063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0339 0.0355
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0093 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0133 0.1043
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0098 0.0366 0.0867
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0207 0.0832 0.0896
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0116 0.0443 0.0469
Brugia malayi hypothetical protein 0.008 0.0292 0.0692
Brugia malayi Pre-SET motif family protein 0.0035 0.0099 0.0233
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0032 0.0018
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.0441 0.0467
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0029 0.0036
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0339 0.0773
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0133 0.1063
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0032
Schistosoma mansoni hypothetical protein 0.0395 0.1632 0.1619
Leishmania major hypothetical protein, conserved 0.0025 0.0056 0.0988
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0079 0.0069
Leishmania major hypothetical protein, conserved 0.0043 0.0133 0.279
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0098 0.0366 0.0351
Plasmodium falciparum thioredoxin reductase 0.0046 0.0145 1
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0133 0.1063
Onchocerca volvulus 0.0098 0.0366 0.3053
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0112 0.0427 0.0412
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0282 1
Brugia malayi hypothetical protein 0.0077 0.0278 0.0658
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0041 0.0065
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0041 0.0027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0041 0.064
Echinococcus granulosus ubiquitin specific protease 41 0.0116 0.0443 0.0469
Brugia malayi Nuclear hormone receptor-like 1 0.0638 0.2667 0.6313
Brugia malayi tailless protein 0.0098 0.0366 0.0867
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0116 0.0443 0.3837
Brugia malayi intermediate filament protein 0.0063 0.0218 0.0515
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0013
Schistosoma mansoni hypothetical protein 0.0395 0.1632 0.1619
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0018 0.0141
Loa Loa (eye worm) TAR-binding protein 0.0138 0.0536 0.124
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0198 0.0468
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0041 0.064
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0048 0.0153 0.015
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0207 0.0832 0.197
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0018 0.01
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0133 0.4463
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0207 0.0832 0.0896
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0045
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0032 0.0016
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Loa Loa (eye worm) hypothetical protein 0.004 0.012 0.0252
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0029 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0099 0.31
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0087
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0018 0.0141
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0207 0.0832 0.0817
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0098 0.0366 0.0351
Schistosoma mansoni thyroid hormone receptor 0.2361 1 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0098 0.0366 0.0838
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0207 0.0832 0.1944
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0099 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0207 0.0832 0.0896
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0207 0.0832 0.0817
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0041 0.0097
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0098 0.0366 0.0351
Echinococcus granulosus voltage dependent calcium channel 0.0112 0.0427 0.0452
Brugia malayi hypothetical protein 0.0016 0.0019 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0098 0.0366 0.0351
Toxoplasma gondii thioredoxin reductase 0.0046 0.0145 0.4854
Brugia malayi Steroid receptor seven-up type 2 0.0207 0.0832 0.197
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0133 0.1063
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0339 0.0803
Echinococcus multilocularis neuropeptide receptor A26 0.0478 0.1987 0.1974
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0099 0.0083
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.0441 0.0425
Loa Loa (eye worm) DR-78 0.0098 0.0366 0.0838
Brugia malayi TAR-binding protein 0.0138 0.0536 0.1268
Mycobacterium ulcerans hypothetical protein 0.0043 0.0133 0.4463
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0443 0.3837
Brugia malayi cytoplasmic intermediate filament protein 0.0034 0.0094 0.0221
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0536 0.0521
Brugia malayi conserved hypotetical protein 0.0098 0.0366 0.0867
Brugia malayi Doublecortin family protein 0.0019 0.0032 0.0077
Brugia malayi Intermediate filament tail domain containing protein 0.0063 0.0218 0.0515
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0133 0.279
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0207 0.0832 0.0817
Loa Loa (eye worm) hypothetical protein 0.0116 0.0443 0.102
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0032 0.0016
Entamoeba histolytica hypothetical protein 0.008 0.0292 0.6248
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0116 0.0443 0.0469
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0041 0.1937
Schistosoma mansoni rab6-interacting 0.0019 0.0032 0.0016
Onchocerca volvulus 0.0063 0.0218 0.1693
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0207 0.0832 0.0817
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Mycobacterium tuberculosis Probable reductase 0.0104 0.0395 0.3431
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0032 0.0016
Schistosoma mansoni RAR-like nuclear receptor 0.0207 0.0832 0.0817
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0018 0.0068
Echinococcus multilocularis amyloid beta A4 protein 0.008 0.0291 0.0276
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0156
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0207 0.0832 0.1944
Loa Loa (eye worm) RNA binding protein 0.0138 0.0536 0.124
Trichomonas vaginalis esterase, putative 0.0043 0.0133 0.1043
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.012 0.0283
Loa Loa (eye worm) nuclear hormone receptor 0.0098 0.0366 0.0838
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0207 0.0832 0.0896
Brugia malayi photoreceptor-specific nuclear receptor 0.0207 0.0832 0.197
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0207 0.0832 0.197
Echinococcus granulosus microtubule associated protein 2 0.0674 0.282 0.308
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0282 0.6253
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0058
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0247 0.2095
Brugia malayi nuclear receptor NHR-88 0.0098 0.0366 0.0867
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0013
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0018 0.01
Plasmodium falciparum glutathione reductase 0.0046 0.0145 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1004 0.4224 1
Brugia malayi beta-lactamase family protein 0.0043 0.0133 0.0316
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0285
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0112 0.0427 0.1012
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0112 0.0427 0.0412
Echinococcus multilocularis lamin 0.0063 0.0218 0.0202
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Loa Loa (eye worm) hypothetical protein 0.0112 0.0427 0.0983
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0041 0.064
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0032 0.1262
Leishmania major trypanothione reductase 0.0046 0.0145 0.3065
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Schistosoma mansoni lamin 0.0063 0.0218 0.0202
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0133 0.0285
Mycobacterium tuberculosis Conserved protein 0.0043 0.0133 0.1063
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0068 0.0241 0.5284
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0116 0.0443 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0207 0.0832 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0207 0.0832 0.197
Toxoplasma gondii hypothetical protein 0.0021 0.0038 0.0832
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0339 0.0324
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0536 0.0521
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0243 0.0983 0.2303
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0145 0.0129
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0133 0.0118
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0116 0.0443 0.0428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0116 0.0443 0.3837
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0068 0.0241 0.5284
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0116 0.0443 0.0428
Echinococcus multilocularis FTZ F1 alpha 0.0207 0.0832 0.0817
Echinococcus granulosus FTZ F1 alpha 0.0207 0.0832 0.0896
Onchocerca volvulus Protein ultraspiracle homolog 0.0207 0.0832 0.7311
Loa Loa (eye worm) hypothetical protein 0.0077 0.0278 0.0628
Onchocerca volvulus 0.0063 0.0218 0.1693
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0109 0.0416 0.0401
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0056 0.1501
Echinococcus granulosus Nuclear hormone receptor HR96 0.0098 0.0366 0.0385
Echinococcus granulosus Nuclear hormone receptor HR96 0.0098 0.0366 0.0385
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0395 0.8405
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0099 0.0083
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0018 0.5
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0207 0.0832 0.197
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0395 0.3431
Schistosoma mansoni hypothetical protein 0.2154 0.9118 0.9117
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0116 0.0443 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0285
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0018 0.01
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.005 0.1284
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0029 0.0068
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Schistosoma mansoni hypothetical protein 0.0019 0.0032 0.0016
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0207 0.0832 0.7311
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0109 0.0416 0.0401
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0013
Echinococcus multilocularis microtubule associated protein 2 0.0674 0.282 0.2808
Brugia malayi Pre-SET motif family protein 0.0243 0.0983 0.2328
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0041 0.1937
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Loa Loa (eye worm) hypothetical protein 0.0109 0.0416 0.0956
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0098 0.0366 0.3053
Echinococcus granulosus geminin 0.0395 0.1632 0.1776
Echinococcus granulosus voltage dependent calcium channel 0.0023 0.005 0.0038
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0018 0.0002
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0112 0.0427 0.0412
Schistosoma mansoni zinc finger protein 0.0098 0.0366 0.0351
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1711 0.7234 0.7229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0207 0.0832 0.0817
Schistosoma mansoni nuclear hormone receptor 0.0098 0.0366 0.0351
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0098 0.0366 0.0351
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0207 0.0832 0.0817
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0145 0.0142
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0638 0.2667 0.6301
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0056 0.0988
Brugia malayi Thioredoxin reductase 0.0046 0.0145 0.0344
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0029 0.0013
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0032 0.1262
Schistosoma mansoni lamin 0.0063 0.0218 0.0202
Brugia malayi hypothetical protein 0.0019 0.0032 0.0077
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0469 0.1081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0207 0.0832 0.1944
Brugia malayi RNA recognition motif domain containing protein 0.0138 0.0536 0.1268
Mycobacterium tuberculosis Conserved protein 0.0043 0.0133 0.1063
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0282 0.0266
Brugia malayi hypothetical protein 0.0109 0.0416 0.0985
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0112 0.0427 0.0452
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0058 0.0198 0.0438
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0056 0.0988
Schistosoma mansoni ap endonuclease 0.0021 0.0041 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Echinococcus multilocularis GPCR, family 2 0.0018 0.0029 0.0013
Echinococcus granulosus neuropeptide receptor A26 0.0478 0.1987 0.2165
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0018 0.01
Brugia malayi RNA binding protein 0.0138 0.0536 0.1268
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0116 0.0443 1
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0032 0.0018
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0018 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0207 0.0832 0.197
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0116 0.0443 0.1049
Brugia malayi beta-lactamase family protein 0.0043 0.0133 0.0316
Echinococcus granulosus lamin 0.0063 0.0218 0.0221
Brugia malayi nuclear receptor RXR 0.0098 0.0366 0.0867
Schistosoma mansoni lipoxygenase 0.0081 0.0293 0.0278
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0112 0.0427 0.0452
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0029 0.0068
Entamoeba histolytica hypothetical protein 0.008 0.0292 0.6248
Echinococcus multilocularis musashi 0.0063 0.0218 0.0202
Echinococcus granulosus nuclear receptor nhr 48 0.0098 0.0366 0.0385
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0145 0.0313
Echinococcus multilocularis tar DNA binding protein 0.0138 0.0536 0.0521
Echinococcus granulosus GPCR family 2 0.0018 0.0029 0.0014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0063 0.0218 0.0484
Echinococcus multilocularis ubiquitin specific protease 41 0.0116 0.0443 0.0428
Echinococcus granulosus neuropeptide s receptor 0.0478 0.1987 0.2165
Onchocerca volvulus 0.0043 0.0133 0.0924
Entamoeba histolytica hypothetical protein 0.008 0.0292 0.6248
Brugia malayi hypothetical protein 0.0098 0.0366 0.0867
Schistosoma mansoni thyroid hormone receptor 0.2361 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.008 0.0292 0.0303
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0444 0.388
Schistosoma mansoni transcription factor LCR-F1 0.008 0.0292 0.0277
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0285
Onchocerca volvulus 0.0035 0.0099 0.0605
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0041 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0029 0.0014
Schistosoma mansoni inositol monophosphatase 0.0078 0.0282 0.0266
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0275 0.112 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0366 0.0385
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0056 0.3093
Plasmodium falciparum glutathione reductase 0.0016 0.0018 0.0141
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0018 0.016
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0016 0.0038
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0145 0.117
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0282 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0098 0.0366 0.3053
Schistosoma mansoni nuclear receptor 0.0098 0.0366 0.0351
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0018 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0207 0.0832 0.197
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0116 0.0443 0.0428
Schistosoma mansoni rab6-interacting 0.0019 0.0032 0.0016
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0013
Loa Loa (eye worm) glutathione reductase 0.0046 0.0145 0.0313
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0395 0.3431
Brugia malayi MH2 domain containing protein 0.0122 0.0469 0.1109
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0282 0.2384
Schistosoma mansoni polycystin 1-related 0.0019 0.0032 0.0016
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0099 0.0083
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Loa Loa (eye worm) hypothetical protein 0.0062 0.0213 0.0473
Echinococcus multilocularis ecdysone induced protein 78C 0.0207 0.0832 0.0817
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0056 0.0988
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0116 0.0443 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0016 0.0058
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0133 0.9088
Onchocerca volvulus 0.0276 0.1126 1
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0072 0.0255 0.0604
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0133 0.279
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0109 0.0416 0.0439
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0207 0.0832 0.1944
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0444 0.388
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0133 0.0129
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0282 0.6253
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0018 0.01
Brugia malayi Nuclear hormone receptor E75 0.0098 0.0366 0.0867
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Brugia malayi Nuclear hormone receptor E75 0.0098 0.0366 0.0867
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0133 0.1043
Loa Loa (eye worm) voltage-dependent calcium channel 0.0023 0.005 0.0087
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0109 0.0416 0.0401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0207 0.0832 0.1944
Loa Loa (eye worm) X11 protein 0.008 0.0291 0.066
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0133 0.0118
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0098 0.0366 0.0351
Brugia malayi Nuclear hormone receptor-like 1 0.0736 0.3083 0.7298
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0207 0.0832 0.197
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0056 0.3093
Schistosoma mansoni coup transcription factor 0.0207 0.0832 0.0817
Schistosoma mansoni ap endonuclease 0.0021 0.0041 0.0025
Brugia malayi ecdysone receptor 0.0098 0.0366 0.0867
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0018 0.0002
Brugia malayi follicle stimulating hormone receptor 0.1004 0.4224 1
Brugia malayi hypothetical protein 0.0019 0.0032 0.0077
Echinococcus multilocularis geminin 0.0395 0.1632 0.1619
Brugia malayi hypothetical protein 0.0025 0.0056 0.0133
Loa Loa (eye worm) inositol-1 0.0078 0.0282 0.0638
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0018 0.016
Schistosoma mansoni steroid hormone receptor ad4bp 0.0207 0.0832 0.0817
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0018 0.0042
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0112 0.0427 0.0412
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0207 0.0832 0.0817
Echinococcus multilocularis lamin dm0 0.0063 0.0218 0.0202
Brugia malayi hypothetical protein 0.0109 0.0416 0.0985
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0285
Brugia malayi orphan nuclear receptor NR2E1 0.0098 0.0366 0.0867
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0018 0.01
Brugia malayi Nuclear hormone receptor-like 1 0.0638 0.2667 0.6313
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0536 0.0521
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Schistosoma mansoni lipoxygenase 0.0115 0.0441 0.0425
Plasmodium vivax SET domain protein, putative 0.0035 0.0099 0.6386
Schistosoma mansoni voltage-gated cation channel 0.0112 0.0427 0.0412
Plasmodium falciparum thioredoxin reductase 0.0016 0.0018 0.0141
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0099 0.0091
Echinococcus granulosus amyloid beta A4 protein 0.008 0.0291 0.0302
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0032 0.0018
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0247 0.3664
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0041 0.0546
Onchocerca volvulus Bile acid receptor homolog 0.0207 0.0832 0.7311
Brugia malayi nuclear receptor NHR-67 0.0098 0.0366 0.0867
Loa Loa (eye worm) hypothetical protein 0.0109 0.0416 0.0956
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0056 0.3093
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0034 0.0094 0.019
Loa Loa (eye worm) calcium channel 0.0112 0.0427 0.0983
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0016 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0207 0.0832 0.0817
Echinococcus granulosus thyroid hormone receptor alpha 0.0098 0.0366 0.0385
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0207 0.0832 0.0896
Mycobacterium ulcerans beta-lactamase 0.0043 0.0133 0.4463
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0395 0.3431
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0018 0.0141
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0016 0.0058
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0029 0.0013
Echinococcus granulosus intermediate filament protein 0.0063 0.0218 0.0221
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0018 0.0068
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0079 0.0063
Brugia malayi nuclear receptor RXR 0.0109 0.0416 0.0985
Schistosoma mansoni inositol monophosphatase 0.0078 0.0282 0.0266
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0198 0.0468
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0018 0.01
Loa Loa (eye worm) hypothetical protein 0.0098 0.0366 0.0838
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0058
Brugia malayi isocitrate dehydrogenase 0.0015 0.0016 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0207 0.0832 0.197
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0112 0.0427 0.0452
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0207 0.0832 0.0896
Schistosoma mansoni amyloid beta A4 protein related 0.008 0.0291 0.0276
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0099 0.0083
Entamoeba histolytica hypothetical protein 0.008 0.0292 0.6248
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0032 0.0045
Brugia malayi hypothetical protein 0.0098 0.0366 0.0867
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0018 0.0141
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0041 0.0209
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0112 0.0427 0.0412
Onchocerca volvulus 0.0207 0.0832 0.7311
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0536 0.0521
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0016 0.0058
Mycobacterium ulcerans lipase LipD 0.0043 0.0133 0.4463
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0282 1
Loa Loa (eye worm) hypothetical protein 0.0207 0.0832 0.1944
Brugia malayi steroid hormone receptor 0.0207 0.0832 0.197
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0099 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0207 0.0832 0.197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0207 0.0832 0.1944
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0282 0.0292
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.2154 0.9118 0.9117
Brugia malayi nuclear hormone receptor family member nhr-6 0.0098 0.0366 0.0867
Loa Loa (eye worm) steroid hormone receptor 0.0207 0.0832 0.1944
Plasmodium vivax glutathione reductase, putative 0.0046 0.0145 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0202
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0339 0.0324
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0041 0.0209
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0041 0.0025
Echinococcus granulosus lamin dm0 0.0063 0.0218 0.0221
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0041 0.0227
Onchocerca volvulus 0.0043 0.0133 0.0924
Schistosoma mansoni retinoic acid receptor RXR 0.0207 0.0832 0.0817
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0018 0.01
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0285
Schistosoma mansoni hypothetical protein 0.004 0.012 0.0104
Brugia malayi nuclear hormone receptor 0.0207 0.0832 0.197
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0444 0.388
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0101
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0282 0.6253
Echinococcus granulosus RUN 0.0019 0.0032 0.0018

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.