Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0367 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.3754 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0035 | 0.0004 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0147 | 0.0771 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0147 | 0.0455 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0018 | 0.013 | 0.0658 |
Brugia malayi | MH2 domain containing protein | 0.0265 | 0.2559 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0018 | 0.013 | 0.0658 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Trypanosoma brucei | hypothetical protein, conserved | 0.016 | 0.1525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0147 | 0.0964 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0367 | 0.0446 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.043 | 0.1575 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0302 | 0.1982 |
Brugia malayi | tailless protein | 0.0009 | 0.0044 | 0.0049 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.016 | 0.1525 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.016 | 0.1525 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0147 | 0.0455 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0009 | 0.0044 | 0.0016 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0147 | 0.0964 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.016 | 0.1525 | 0.5908 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0147 | 0.0964 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.013 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0147 | 0.0964 |
Brugia malayi | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0032 | 0.0209 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.016 | 0.1525 | 0.1272 |
Brugia malayi | Smad1 | 0.0018 | 0.013 | 0.0389 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0147 | 0.0964 |
Onchocerca volvulus | Huntingtin homolog | 0.0257 | 0.2482 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0147 | 0.0455 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0035 | 0.0228 |
Mycobacterium tuberculosis | Probable hydrolase | 0.016 | 0.1525 | 0.1272 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0147 | 0.0771 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0147 | 0.0455 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0147 | 0.0455 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0035 | 0.0004 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0147 | 0.0455 |
Schistosoma mansoni | nuclear receptor | 0.0009 | 0.0044 | 0.029 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0367 | 0.2406 |
Onchocerca volvulus | 0.0009 | 0.0044 | 0.005 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.016 | 0.1525 | 0.1272 |
Schistosoma mansoni | smad | 0.0008 | 0.0032 | 0.0209 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.016 | 0.1525 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0009 | 0.0044 | 0.0049 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0147 | 0.0455 |
Mycobacterium ulcerans | hypothetical protein | 0.016 | 0.1525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0367 | 0.2406 |
Loa Loa (eye worm) | DR-78 | 0.0009 | 0.0044 | 0.0049 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0147 | 0.0455 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0302 | 0.1982 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.0283 | 0.0995 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.033 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0147 | 0.0153 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.033 | 0.1994 |
Brugia malayi | nuclear receptor NHR-67 | 0.0009 | 0.0044 | 0.0049 |
Onchocerca volvulus | Huntingtin homolog | 0.0257 | 0.2482 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.016 | 0.1525 | 0.1272 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0147 | 0.0455 |
Onchocerca volvulus | 0.016 | 0.1525 | 0.6095 | |
Brugia malayi | nuclear receptor RXR | 0.0009 | 0.0044 | 0.0049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0147 | 0.0455 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.2032 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.016 | 0.1525 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.016 | 0.1525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1525 | 0.5908 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0032 | 0.0209 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.016 | 0.1525 | 0.5908 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0367 | 0.1326 |
Mycobacterium leprae | conserved hypothetical protein | 0.016 | 0.1525 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0265 | 0.2559 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0009 | 0.0044 | 0.0016 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0367 | 0.2244 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.016 | 0.1525 | 1 |
Onchocerca volvulus | 0.002 | 0.0147 | 0.047 | |
Mycobacterium tuberculosis | Conserved protein | 0.016 | 0.1525 | 0.1272 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0009 | 0.0044 | 0.0049 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.043 | 0.2665 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0367 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.013 | 0.0389 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.2032 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0009 | 0.0044 | 0.005 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.016 | 0.1525 | 0.1987 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.043 | 0.053 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0147 | 0.0455 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.016 | 0.1525 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.001 | 0.0055 | 0.0092 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.001 | 0.0055 | 0.0031 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0009 | 0.0044 | 0.029 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.016 | 0.1525 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0055 | 0.0092 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.043 | 0.053 |
Brugia malayi | nuclear receptor NHR-88 | 0.0009 | 0.0044 | 0.0049 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0147 | 0.047 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.016 | 0.1525 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0018 | 0.013 | 0.0131 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.2482 | 0.9695 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0009 | 0.0044 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.2482 | 0.9695 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.013 | 0.0389 |
Brugia malayi | MH1 domain containing protein | 0.001 | 0.0051 | 0.0075 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.033 | 0.2161 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0009 | 0.0044 | 0.029 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0367 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0302 | 0.036 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.043 | 0.1575 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0009 | 0.0044 | 0.0016 |
Mycobacterium ulcerans | beta-lactamase | 0.016 | 0.1525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0147 | 0.0964 |
Schistosoma mansoni | Smad4 | 0.0018 | 0.013 | 0.0853 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0009 | 0.0044 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Onchocerca volvulus | 0.016 | 0.1525 | 0.6095 | |
Mycobacterium ulcerans | lipase LipD | 0.016 | 0.1525 | 1 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0009 | 0.0044 | 0.0049 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.2032 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1525 | 0.5908 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1525 | 0.5908 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0147 | 0.0153 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0051 | 0.0075 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0009 | 0.0044 | 0.029 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0147 | 0.047 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0018 | 0.013 | 0.0389 |
Brugia malayi | nuclear hormone receptor | 0.0009 | 0.0044 | 0.0049 |
Brugia malayi | MH1 domain containing protein | 0.001 | 0.0051 | 0.0075 |
Loa Loa (eye worm) | Smad1 | 0.0018 | 0.013 | 0.0389 |
Brugia malayi | ecdysone receptor | 0.0009 | 0.0044 | 0.0049 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.033 | 0.1178 |
Onchocerca volvulus | 0.0034 | 0.0283 | 0.1026 | |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.2032 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0009 | 0.0044 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Toxoplasma gondii | ABC1 family protein | 0.016 | 0.1525 | 1 |
Leishmania major | hypothetical protein, conserved | 0.016 | 0.1525 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0283 | 0.1858 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.0654 | 0.429 |
Brugia malayi | beta-lactamase family protein | 0.016 | 0.1525 | 0.5908 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0009 | 0.0044 | 0.0083 |
Plasmodium vivax | hypothetical protein, conserved | 0.016 | 0.1525 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.033 | 0.2017 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0055 | 0.0092 |
Trichomonas vaginalis | esterase, putative | 0.016 | 0.1525 | 1 |
Echinococcus multilocularis | Smad4 | 0.0018 | 0.013 | 0.0658 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.001 | 0.0055 | 0.0156 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0035 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0147 | 0.0771 |
Brugia malayi | Inositol-1 | 0.0038 | 0.033 | 0.1178 |
Schistosoma mansoni | smad1 5 8 and | 0.0018 | 0.013 | 0.0853 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0147 | 0.0455 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0147 | 0.0771 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.0579 | 0.2089 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0147 | 0.0964 |
Schistosoma mansoni | zinc finger protein | 0.0009 | 0.0044 | 0.029 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.016 | 0.1525 | 0.1272 |
Onchocerca volvulus | 0.0009 | 0.0044 | 0.005 | |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0009 | 0.0044 | 0.0083 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | beta-lactamase | 0.016 | 0.1525 | 0.5908 |
Loa Loa (eye worm) | nuclear factor I | 0.001 | 0.0051 | 0.0075 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1525 | 0.5908 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0018 | 0.013 | 0.0853 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0055 | 0.0154 |
Echinococcus granulosus | smad | 0.0018 | 0.013 | 0.0131 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0147 | 0.0964 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0147 | 0.0771 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.033 | 0.2017 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1525 | 0.5908 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0055 | 0.0031 |
Schistosoma mansoni | nuclear receptor | 0.0009 | 0.0044 | 0.029 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0055 | 0.0363 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0302 | 0.181 |
Onchocerca volvulus | 0.016 | 0.1525 | 0.6095 | |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.0573 | 0.0719 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.0573 | 0.2032 |
Echinococcus granulosus | Smad4 | 0.0018 | 0.013 | 0.0131 |
Schistosoma mansoni | smad | 0.0018 | 0.013 | 0.0853 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0147 | 0.0771 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.043 | 0.2665 |
Echinococcus granulosus | FTZ F1 alpha | 0.0773 | 0.7548 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.016 | 0.1525 | 0.1272 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0009 | 0.0044 | 0.0049 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0147 | 0.0771 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0147 | 0.0964 |
Brugia malayi | beta-lactamase family protein | 0.016 | 0.1525 | 0.5908 |
Brugia malayi | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.0283 | 0.0995 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.013 | 0.0389 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0147 | 0.0153 |
Schistosoma mansoni | nuclear hormone receptor | 0.0009 | 0.0044 | 0.029 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0009 | 0.0044 | 0.0049 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.033 | 0.2017 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Brugia malayi | beta-lactamase | 0.016 | 0.1525 | 0.5908 |
Schistosoma mansoni | nuclear hormone receptor | 0.0009 | 0.0044 | 0.029 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0035 | 0.0019 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.016 | 0.1525 | 0.1272 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0009 | 0.0044 | 0.0049 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.016 | 0.1525 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0147 | 0.0455 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0009 | 0.0044 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0147 | 0.0964 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0147 | 0.0455 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0147 | 0.0771 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0147 | 0.0455 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.0573 | 0.362 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1525 | 0.5908 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.016 | 0.1525 | 1 |
Echinococcus multilocularis | smad | 0.0018 | 0.013 | 0.0658 |
Mycobacterium tuberculosis | Conserved protein | 0.016 | 0.1525 | 0.1272 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.043 | 0.2819 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.043 | 0.2819 |
Schistosoma mansoni | smad1 5 8 and | 0.0018 | 0.013 | 0.0853 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0147 | 0.0455 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0009 | 0.0044 | 0.0083 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0147 | 0.0153 |
Mycobacterium leprae | Probable lipase LipE | 0.016 | 0.1525 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0147 | 0.0771 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.033 | 0.0396 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0147 | 0.0455 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0147 | 0.0964 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0009 | 0.0044 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Brugia malayi | conserved hypotetical protein | 0.0009 | 0.0044 | 0.0049 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0147 | 0.0153 |
Schistosoma mansoni | smad1 5 8 and | 0.0018 | 0.013 | 0.0853 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.016 | 0.1525 | 0.1272 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.033 | 0.2161 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0147 | 0.0153 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0018 | 0.013 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0257 | 0.2482 | 0.9695 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0265 | 0.2559 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0147 | 0.0153 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0147 | 0.0455 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.043 | 0.2819 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0009 | 0.0044 | 0.0083 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0009 | 0.0044 | 0.0049 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0009 | 0.0044 | 0.0016 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.001 | 0.0055 | 0.0363 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.3754 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0009 | 0.0044 | 0.0049 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.016 | 0.1525 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0147 | 0.0964 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0147 | 0.0964 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0147 | 0.047 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.0573 | 0.0291 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0009 | 0.0044 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0147 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0044 | 0.0049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0147 | 0.0455 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0054 | 0.0086 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0147 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0055 | 0.0091 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0055 | 0.0092 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0018 | 0.013 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0055 | 0.0092 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IP (functional) | = 37 nM | Allosteric modulation of human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced calcium mobilization by FLIPR assay | ChEMBL. | 20004574 |
PPB (ADMET) | = 98 % | Plasma protein binding in human serum by equilibrium dialysis method | ChEMBL. | 20004574 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.