Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0629 | 0.1562 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0106 | 0.0107 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0629 | 0.201 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0057 | 0.0183 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.108 | 0.3453 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.108 | 0.1088 |
Onchocerca volvulus | 0.003 | 0.0228 | 0.0814 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0629 | 0.201 |
Echinococcus multilocularis | geminin | 0.0338 | 0.4027 | 0.4054 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.1379 | 0.4926 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0629 | 0.0633 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0382 | 0.1221 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0057 | 0.0142 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0106 | 0.0107 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0816 | 0.9933 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0363 | 0.0902 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.2443 | 0.7809 |
Schistosoma mansoni | hypothetical protein | 0.029 | 0.3437 | 0.8535 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0265 | 0.3129 | 0.315 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0228 | 0.0729 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0022 | 0.0123 | 0.0124 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0265 | 0.3129 | 0.7769 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0265 | 0.3129 | 0.7769 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0057 | 0.0142 |
Echinococcus multilocularis | potassium voltage gated channel subfamily C | 0.0022 | 0.0123 | 0.0124 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0445 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.108 | 0.3453 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.2738 | 0.8751 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0057 | 0.0183 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0106 | 0.0107 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0456 | 0.0459 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0106 | 0.0263 |
Schistosoma mansoni | smad | 0.0016 | 0.0057 | 0.0142 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0106 | 0.0338 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0382 | 0.0949 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0106 | 0.0338 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0414 | 0.0417 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0414 | 0.1324 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0057 | 0.0058 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0742 | 0.2373 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.28 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0629 | 0.1562 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0228 | 0.0566 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0382 | 0.0949 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.2443 | 0.7809 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0072 | 0.0742 | 0.1844 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0106 | 0.0338 |
Onchocerca volvulus | 0.002 | 0.0106 | 0.0378 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0057 | 0.0183 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0057 | 0.0183 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0265 | 0.3129 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0106 | 0.0263 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0106 | 0.0338 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.108 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0106 | 0.0107 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0022 | 0.0123 | 0.0124 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0248 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0106 | 0.0338 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0414 | 0.1029 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0022 | 0.0123 | 0.0124 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0106 | 0.0263 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0057 | 0.0183 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0106 | 0.0338 |
Echinococcus multilocularis | X box binding protein 1 | 0.029 | 0.3437 | 0.346 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 0.4027 | 1 |
Echinococcus granulosus | geminin | 0.0338 | 0.4027 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 0.4027 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0106 | 0.0263 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0022 | 0.0123 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0106 | 0.0338 |
Echinococcus granulosus | potassium voltage gated channel subfamily C | 0.0022 | 0.0123 | 0.0306 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0238 | 0.2795 | 0.8933 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0228 | 0.023 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0228 | 0.9273 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0057 | 0.0058 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0414 | 0.1029 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0246 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0629 | 0.201 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0106 | 0.0378 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0106 | 0.0107 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0106 | 0.0263 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0265 | 0.3129 | 0.7769 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0414 | 0.1029 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0057 | 0.0058 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0414 | 0.1029 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0248 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0382 | 0.0949 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0106 | 0.0107 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0248 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0106 | 0.0263 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0214 | 0.0532 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0022 | 0.0123 | 0.0306 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.108 | 0.2683 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0238 | 0.2795 | 0.8933 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.05 | 0.1599 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0228 | 0.0566 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0022 | 0.0123 | 0.0306 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0106 | 0.0338 |
Brugia malayi | MH2 domain containing protein | 0.0238 | 0.2795 | 0.8933 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0057 | 0.0142 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0106 | 0.0338 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0611 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0106 | 0.0263 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0382 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0022 | 0.0123 | 0.0394 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0106 | 0.0263 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0106 | 0.0338 |
Brugia malayi | hypothetical protein | 0.0233 | 0.2738 | 0.8751 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0106 | 0.0263 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.1605 | 0.1616 |
Onchocerca volvulus | 0.0048 | 0.0445 | 0.1588 | |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0106 | 0.0263 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0106 | 0.0338 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0057 | 0.0142 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0072 | 0.0742 | 0.1844 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0106 | 0.0263 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0629 | 0.201 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0786 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0394 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0246 | 1 |
Mycobacterium ulcerans | proteasome PrcA | 0.0821 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0106 | 0.0338 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0057 | 0.0183 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0106 | 0.0107 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0106 | 0.0338 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0106 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0248 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0445 | 0.1104 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0382 | 0.1221 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0106 | 0.0263 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0246 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.1006 | 0.2499 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.1006 | 0.1013 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0.0246 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.2738 | 0.2756 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0414 | 0.1324 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0022 | 0.0123 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0382 | 0.1221 |
Echinococcus granulosus | smad | 0.0016 | 0.0057 | 0.0142 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0629 | 0.1562 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0022 | 0.0123 | 0.0124 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0228 | 0.0566 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0106 | 0.0263 |
Echinococcus granulosus | voltage gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0363 | 0.0902 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0057 | 0.0142 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0106 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.3129 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0106 | 0.0263 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0228 | 0.023 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0611 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.2738 | 0.6799 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0057 | 0.0142 |
Brugia malayi | hypothetical protein | 0.0123 | 0.1379 | 0.4409 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0629 | 0.201 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0629 | 0.1562 |
Onchocerca volvulus | 0.0238 | 0.28 | 1 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0106 | 0.0263 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0022 | 0.0123 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1379 | 0.4409 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0057 | 0.0183 |
Brugia malayi | Smad1 | 0.0016 | 0.0057 | 0.0183 |
Schistosoma mansoni | vesicular amine transporter | 0.0022 | 0.0123 | 0.0306 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.1605 | 0.3987 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0629 | 0.201 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0106 | 0.0378 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0629 | 0.1562 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0106 | 0.0378 |
Echinococcus multilocularis | shaker cognate | 0.0022 | 0.0123 | 0.0124 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0106 | 0.0338 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0106 | 0.0338 |
Echinococcus granulosus | X box binding protein 1 | 0.029 | 0.3437 | 0.8535 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0228 | 0.0729 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0106 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0106 | 0.0107 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.1099 | 0.273 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0106 | 0.0263 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0106 | 0.0263 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0106 | 0.0263 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0629 | 0.1562 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0123 | 0.0394 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0742 | 0.1844 |
Echinococcus multilocularis | smad | 0.0016 | 0.0057 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0363 | 0.0902 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0246 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0106 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.1379 | 0.4926 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0786 |
Echinococcus granulosus | shaker cognate | 0.0022 | 0.0123 | 0.0306 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0228 | 0.0566 |
Echinococcus granulosus | Potassium voltage gated channel protein Shaw | 0.0022 | 0.0123 | 0.0306 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0106 | 0.0338 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0.0246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1379 | 0.4409 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog | 0.0022 | 0.0123 | 0.0394 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0072 | 0.0742 | 0.0747 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0057 | 0.0142 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.0821 | 1 | 1 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0382 | 0.0385 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0022 | 0.0123 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0338 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0414 | 0.1029 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0265 | 0.3129 | 0.7769 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0106 | 0.0338 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0106 | 0.0338 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0414 | 0.0417 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0253 | 0.2986 | 0.3006 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0445 | 0.1421 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0.0246 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0057 | 0.0142 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0228 | 0.0566 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0363 | 0.0902 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0246 | 0.0248 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0228 | 0.9273 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0246 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0.0246 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0106 | 0.0338 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0106 | 0.0263 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0246 | 0.0786 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0022 | 0.0123 | 0.0306 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0106 | 0.0338 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED25 (functional) | = 100 uM kg-1 | In vivo inhibition of glucose load induced hyperglycaemia in fasted C57B1/6 ob/ob mice. | ChEMBL. | No reference |
ED25 (functional) | = 100 uM kg-1 | In vivo inhibition of glucose load induced hyperglycaemia in fasted C57B1/6 ob/ob mice. | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.