Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tar DNA binding protein | 0.0141 | 0.3181 | 0.3176 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.043 | 1 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0015 | 0.0199 | 0.228 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.0348 | 0.0345 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0043 | 0.0873 | 0.0866 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0072 | 0.0064 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0072 | 0.0068 |
Brugia malayi | N-terminal motif family protein | 0.0192 | 0.4385 | 0.4383 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.0199 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0226 | 0.5184 | 0.5182 |
Trypanosoma cruzi | guanine nucleotide releasing protein, putative | 0.0007 | 0.0008 | 0.0004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.2148 | 0.2465 |
Brugia malayi | N-terminal motif family protein | 0.0007 | 0.0008 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0072 | 0.0068 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.2148 | 0.2142 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0614 | 0.0704 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.043 | 1 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0043 | 0.0859 | 0.0856 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0007 | 0.0008 | 0.0009 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0072 | 0.0082 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0015 | 0.0199 | 0.566 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0072 | 0.0082 |
Schistosoma mansoni | hypothetical protein | 0.0376 | 0.8717 | 1 |
Treponema pallidum | NADH oxidase | 0.0015 | 0.0199 | 0.5 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0015 | 0.0199 | 0.0195 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.0348 | 0.0341 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.0348 | 0.0576 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.3181 | 0.365 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0072 | 0.0064 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0015 | 0.0199 | 0.566 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0015 | 0.0199 | 0.228 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0072 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0008 | 0.0004 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0614 | 0.0704 |
Brugia malayi | RasGEF domain containing protein | 0.0007 | 0.0008 | 0.0004 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Toxoplasma gondii | hypothetical protein | 0.0009 | 0.0072 | 0.0797 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0141 | 0.3181 | 0.3179 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.5973 | 0.5971 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.043 | 1 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.3181 | 0.365 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0072 | 0.0068 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0109 | 0.2411 | 1 |
Echinococcus granulosus | geminin | 0.0376 | 0.8717 | 0.8716 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0015 | 0.0199 | 0.228 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0348 | 0.0345 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0015 | 0.0199 | 0.0323 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0348 | 0.0676 |
Loa Loa (eye worm) | RNA binding protein | 0.0141 | 0.3181 | 0.3179 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.1098 | 0.1259 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0614 | 0.0607 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0614 | 0.7132 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0348 | 0.0345 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.1098 | 0.1094 |
Brugia malayi | hypothetical protein | 0.0259 | 0.5973 | 0.5971 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0015 | 0.0199 | 0.0195 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.0199 | 0.5 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0015 | 0.0199 | 0.228 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0109 | 0.2411 | 1 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0072 | 0.0082 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0043 | 0.0873 | 0.0866 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0015 | 0.0199 | 0.0195 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.043 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Brugia malayi | Thioredoxin reductase | 0.0043 | 0.0859 | 0.0856 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0015 | 0.0199 | 0.0228 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0015 | 0.0199 | 0.0195 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0348 | 0.0345 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0348 | 0.0341 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.2148 | 0.2465 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0072 | 0.0064 |
Brugia malayi | RNA binding protein | 0.0141 | 0.3181 | 0.3179 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0011 | 0.0106 | 0.0102 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0007 | 0.0008 | 0.0004 |
Plasmodium vivax | glutathione reductase, putative | 0.0043 | 0.0859 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0614 | 0.061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.3181 | 0.365 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0348 | 0.0345 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0015 | 0.0199 | 0.0195 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0193 | 0.019 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0072 | 0.0068 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0348 | 0.0341 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.1098 | 0.1259 |
Toxoplasma gondii | thioredoxin reductase | 0.0043 | 0.0859 | 1 |
Onchocerca volvulus | 0.0009 | 0.0072 | 0.0108 | |
Plasmodium falciparum | thioredoxin reductase | 0.0043 | 0.0859 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0015 | 0.0199 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0072 | 0.0082 |
Onchocerca volvulus | 0.0257 | 0.5921 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0348 | 0.0345 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.3181 | 0.365 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0011 | 0.0106 | 0.0102 |
Brugia malayi | TAR-binding protein | 0.0141 | 0.3181 | 0.3179 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0008 | 0.0009 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0348 | 1 |
Schistosoma mansoni | ras GTP exchange factor | 0.0007 | 0.0008 | 0.0009 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.0348 | 0.0341 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0193 | 0.019 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0348 | 0.0345 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.0348 | 0.0345 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0098 | 0.2154 | 0.8837 |
Brugia malayi | N-terminal motif family protein | 0.0007 | 0.0008 | 0.0004 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0072 | 0.0068 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.3181 | 0.365 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0259 | 0.5973 | 0.5969 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0072 | 0.0068 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.0348 | 0.04 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.043 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0257 | 0.5921 | 1 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.043 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.2148 | 0.2142 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0015 | 0.0199 | 0.228 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0072 | 0.0064 |
Mycobacterium tuberculosis | Probable reductase | 0.0098 | 0.2154 | 0.8837 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0586 | 0.0578 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0193 | 0.019 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0072 | 0.0082 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.043 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0008 | 0.0004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.2148 | 0.2465 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0193 | 0.019 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.0348 | 0.04 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0072 | 0.0068 |
Echinococcus multilocularis | geminin | 0.0376 | 0.8717 | 0.8716 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0072 | 0.0082 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0072 | 0.0064 |
Plasmodium falciparum | thioredoxin reductase | 0.0015 | 0.0199 | 0.228 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0098 | 0.2154 | 0.8837 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0043 | 0.0859 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0015 | 0.0199 | 0.0191 |
Onchocerca volvulus | 0.0032 | 0.0614 | 0.1025 | |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.0348 | 0.04 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0015 | 0.0199 | 0.228 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0259 | 0.5973 | 0.5969 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0072 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.4385 | 0.4383 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0192 | 0.4385 | 0.7402 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0072 | 0.0064 |
Brugia malayi | RasGEF domain containing protein | 0.0007 | 0.0008 | 0.0004 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0098 | 0.2154 | 0.8837 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0008 | 0.0009 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0007 | 0.0008 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.2148 | 0.2142 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0072 | 0.0108 |
Schistosoma mansoni | hypothetical protein | 0.0376 | 0.8717 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0015 | 0.0199 | 0.228 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0348 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0226 | 0.5184 | 0.5182 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0614 | 0.0607 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Leishmania major | trypanothione reductase | 0.0043 | 0.0859 | 0.0856 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.043 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0072 | 0.0068 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0043 | 0.0859 | 0.0856 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0072 | 0.0064 |
Loa Loa (eye worm) | TAR-binding protein | 0.0141 | 0.3181 | 0.3179 |
Onchocerca volvulus | 0.0053 | 0.1098 | 0.1843 | |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0007 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0109 | 0.2411 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0043 | 0.0859 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.0348 | 0.0576 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0043 | 0.0859 | 0.0856 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0098 | 0.2154 | 0.8837 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0008 | 0.0009 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0348 | 0.0676 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0043 | 0.0859 | 0.2985 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0614 | 0.061 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0614 | 0.0607 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.043 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein | 0.0007 | 0.0008 | 0.0004 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.043 | 1 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0098 | 0.2154 | 0.8837 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0097 | 0.2148 | 0.2145 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0072 | 0.0064 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0015 | 0.0199 | 0.0195 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.0348 | 0.0341 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Echinococcus multilocularis | tar DNA binding protein | 0.0141 | 0.3181 | 0.3176 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.0348 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.043 | 1 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0015 | 0.0199 | 0.0323 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0072 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0072 | 0.0068 |
Trypanosoma brucei | trypanothione reductase | 0.0043 | 0.0859 | 0.0856 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0348 | 1 |
Brugia malayi | RasGEF domain containing protein | 0.0007 | 0.0008 | 0.0004 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0015 | 0.0199 | 0.566 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0015 | 0.0199 | 0.566 |
Trypanosoma cruzi | hypothetical protein | 0.0007 | 0.0008 | 0.0004 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.0348 | 0.0341 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0614 | 0.0704 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0015 | 0.0199 | 0.0195 |
Brugia malayi | glutathione reductase | 0.0043 | 0.0859 | 0.0856 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0015 | 0.0199 | 0.0195 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0141 | 0.3181 | 0.3179 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0007 | 0.0008 | 0.0004 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0348 | 0.0345 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0614 | 0.7132 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0109 | 0.2411 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0348 | 0.0345 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0193 | 0.019 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0097 | 0.2148 | 0.2145 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0199 | 0.0195 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0072 | 0.0068 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.2148 | 0.2142 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0348 | 0.0345 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0614 | 0.0704 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0015 | 0.0199 | 0.0191 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.