Detailed information for compound 109062

Basic information

Technical information
  • TDR Targets ID: 109062
  • Name: 2-ethylphenoxathiine 10,10-dioxide
  • MW: 260.308 | Formula: C14H12O3S
  • H donors: 0 H acceptors: 2 LogP: 3.12 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc2c(c1)S(=O)(=O)c1c(O2)cccc1
  • InChi: 1S/C14H12O3S/c1-2-10-7-8-12-14(9-10)18(15,16)13-6-4-3-5-11(13)17-12/h3-9H,2H2,1H3
  • InChiKey: HDRNHHBGLXBGMQ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Monoamine oxidase A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Get druggable targets OG5_130722 All targets in OG5_130722

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   526 aa 518 aa 22.4 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   526 aa 524 aa 22.9 %
Brugia malayi amine oxidase, flavin-containing family protein Monoamine oxidase A   526 aa 464 aa 21.6 %
Dictyostelium discoideum amine oxidase Monoamine oxidase A   526 aa 491 aa 31.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0027
Schistosoma mansoni DNA helicase recq1 0.0019 0.002 0.0052
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.3595
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0359 0.1535 0.1535
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0122 0.0601
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0027
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0019 0.0264
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0026 0.0053 0.0548
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0095 0.0166
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0026 0.0053 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.01 0.0174
Brugia malayi Protein cec-1. 0.0034 0.0088 0.0499
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.0186 0.0475
Toxoplasma gondii cathepsin CPC1 0.0018 0.0018 0.0065
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0018 0.009
Plasmodium vivax vivapain-1 0.004 0.0115 0.1852
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Mycobacterium ulcerans DNA polymerase IV 0.0144 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0089 0.0334 0.1649
Schistosoma mansoni hypothetical protein 0.0047 0.0148 0.0378
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.033 0.0843
Leishmania major P-type ATPase, putative 0.0076 0.0277 0.3912
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0045 0.046
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0124 0.049 0.0684
Trypanosoma cruzi cysteine peptidase, putative 0.1298 0.5719 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0208 0.0532
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0133 0.1886
Loa Loa (eye worm) hypothetical protein 0.0097 0.0367 0.1815
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0163 0.2757
Echinococcus granulosus Na:K ATPase alpha subunit 0.0066 0.0232 0.0593
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0174 0.2457
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.0186 0.2995
Loa Loa (eye worm) Smad1 0.0027 0.0056 0.0275
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0057 0.0191 0.0489
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0018 0.0293
Toxoplasma gondii cathepsin CPC2 0.0018 0.0018 0.0065
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0308
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.2457
Schistosoma mansoni amine oxidase 0.0025 0.005 0.0127
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0975 1
Treponema pallidum NADH oxidase 0.0053 0.0174 0.0174
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.05 0.0874
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.0304
Leishmania major P-type H -ATPase, putative 0.0053 0.0172 0.2424
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0018 0.0065
Brugia malayi Thioredoxin reductase 0.0153 0.062 0.3505
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0139 0.0355
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.002 0.0052
Echinococcus multilocularis chromobox protein 1 0.015 0.0606 0.1549
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0018 0.0103
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0026 0.0053 0.0137
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0026 0.0053 0.0075
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0133 0.0233
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Onchocerca volvulus 0.0018 0.0018 0.0186
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0056 0.0142
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0172 0.03
Brugia malayi CHD4 protein 0.0036 0.0095 0.0539
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0076 0.0277 0.0708
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0057 0.0191 0.0489
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.016 0.0409
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Brugia malayi Cathepsin L-like precursor 0.0056 0.0186 0.105
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0018 0.0293
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.035 0.1495 0.2088
Schistosoma mansoni hypothetical protein 0.0051 0.0163 0.0417
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0018 0.0032
Brugia malayi intermediate filament protein 0.0026 0.0055 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0441
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0174 0.1784
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0334 0.3424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0025 0.005 0.005
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0167
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0133 0.1886
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0298
Brugia malayi hypothetical protein 0.0119 0.0469 0.265
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0115 0.1852
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0023 0.006
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0755
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Echinococcus multilocularis lamin 0.0026 0.0055 0.0141
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.016 0.2257
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0122 0.0311
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0245
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.03 0.0768
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.1724 0.4408
Schistosoma mansoni chromobox protein 0.015 0.0606 0.1549
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0186 0.0475
Onchocerca volvulus 0.0028 0.0063 0.0642
Onchocerca volvulus 0.0048 0.0153 0.1571
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2259 1 1
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0093 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0056 0.0275
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.035 0.4951
Brugia malayi calcium ATPase 0.004 0.0116 0.0656
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.01 0.1409
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0115 0.1623
Echinococcus multilocularis musashi 0.0026 0.0055 0.0141
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.016 0.0576
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.033 0.0843
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0385 0.0983
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0011 0.0027
Brugia malayi MH2 domain containing protein 0.0027 0.0056 0.0315
Brugia malayi hypothetical protein 0.012 0.0472 0.2669
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0186 0.1905
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0245
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0057 0.0191 0.0489
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0122 0.0311
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0174 0.0304
Brugia malayi hypothetical protein 0.0019 0.0023 0.0132
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0018 0.0293
Echinococcus granulosus cation transporting ATPase 13A3 0.0026 0.0053 0.0137
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0114 0.1841
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0164 0.1679
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0016
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0163 0.2757
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Echinococcus multilocularis protein patched 0.0041 0.0122 0.0311
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0133 0.0341
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0115 0.1948
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0239 0.0611
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0101 0.0386 0.2181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Brugia malayi Valyl-tRNA synthetase 0.0034 0.0088 0.0499
Leishmania major cathepsin L-like protease 0.0056 0.0186 0.2626
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.0129 0.0463
Plasmodium falciparum phosphodiesterase delta, putative 0.0057 0.0191 0.3081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0186
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0057 0.019 0.3215
Onchocerca volvulus 0.0047 0.0148 0.1516
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0039 0.0634
Echinococcus granulosus GPCR family 2 0.0017 0.0012 0.0031
Echinococcus granulosus neuropeptide s receptor 0.046 0.1985 0.5075
Loa Loa (eye worm) hypothetical protein 0.0063 0.0216 0.1067
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0066 0.0232 0.0593
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0074 0.0268 0.1513
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Giardia lamblia hypothetical protein 0.0057 0.0191 0.0944
Brugia malayi Membrane calcium atpase protein 3 0.0076 0.0277 0.1564
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0023 0.0115
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0115 0.0294
Echinococcus granulosus cation transporting ATPase 13A1 0.0026 0.0053 0.0137
Echinococcus multilocularis RUN 0.0019 0.0023 0.006
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0093 0.035 0.1731
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0014 0.0000034129 0.0000087269
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Echinococcus multilocularis cathepsin L 0.0018 0.0018 0.0046
Trypanosoma cruzi trypanothione reductase, putative 0.0153 0.062 0.1085
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0088 0.0318
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Echinococcus granulosus lamin 0.0026 0.0055 0.0141
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0111 0.0628
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0115 0.0294
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0191 0.0334
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0191 0.1961
Echinococcus multilocularis cation transporting ATPase 13A1 0.0026 0.0053 0.0137
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0057 0.0191 0.2701
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0018 0.0256
Onchocerca volvulus Huntingtin homolog 0.012 0.0472 0.4844
Schistosoma mansoni hypothetical protein 0.0019 0.0023 0.006
Brugia malayi Cytochrome P450 family protein 0.0026 0.0051 0.0291
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis pc-MYB2, putative 0.0051 0.0163 0.1668
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.005 0.0087
Loa Loa (eye worm) hypothetical protein 0.0232 0.097 0.4794
Brugia malayi hypothetical protein 0.0033 0.0084 0.0473
Schistosoma mansoni cpg binding protein 0.0028 0.0063 0.016
Echinococcus multilocularis lamin dm0 0.0026 0.0055 0.0141
Trypanosoma brucei calcium-translocating P-type ATPase 0.0101 0.0386 0.5454
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0095 0.0976
Mycobacterium tuberculosis Putative ferredoxin reductase 0.035 0.1495 0.2088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Giardia lamblia DNA damage repair protein 0.0036 0.01 0.0493
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.3595
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Plasmodium falciparum DNA repair protein REV1, putative 0.0036 0.01 0.1608
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0057 0.0191 0.0489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0026 0.0053 0.0193
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0385 0.0983
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.01 0.0174
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0633
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0026 0.0053 0.0075
Echinococcus granulosus Chromobox protein 3 0.0034 0.0088 0.0226
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0186 0.0475
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0011 0.0019
Plasmodium vivax SET domain protein, putative 0.003 0.007 0.1133
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0172 0.2424
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.007 0.018
Giardia lamblia Cathepsin L-like protease 0.0018 0.0018 0.009
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0018 0.0032
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0093 0.035 0.4951
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0023 0.006
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0093 0.035 0.3595
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0115 0.1948
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0076 0.0277 0.0708
Echinococcus granulosus cathepsin l1 0.0056 0.0186 0.0475
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0191 0.3081
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0056 0.0187 0.0926
Onchocerca volvulus 0.0064 0.0221 0.227
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0117 0.0459 0.0459
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.3081
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0057 0.0191 0.0489
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.097 0.2481
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0308
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0042
Schistosoma mansoni cpg binding protein 0.003 0.007 0.0178
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.0088 0.0226
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0083 0.03
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.0436
Trichomonas vaginalis DNA polymerase eta, putative 0.0144 0.0577 0.5921
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0167
Brugia malayi follicle stimulating hormone receptor 0.0234 0.098 0.5538
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0011 0.0019
Echinococcus multilocularis neuropeptide receptor A26 0.046 0.1985 0.5075
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0191 0.0334
Echinococcus multilocularis dna polymerase kappa 0.0144 0.0577 0.1476
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0552 0.1411
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Echinococcus granulosus microtubule associated protein 2 0.0677 0.2951 0.7547
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0076 0.0277 0.0998
Echinococcus granulosus thioredoxin glutathione reductase 0.0153 0.062 0.1586
Leishmania major hypothetical protein, conserved 0.0057 0.0191 0.2701
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.016 0.0789
Brugia malayi polk-prov protein 0.0063 0.0216 0.122
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0327 0.4624
Plasmodium falciparum copper-transporting ATPase 0.0026 0.0053 0.0861
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.059 0.1508
Schistosoma mansoni glutamate synthase 0.0014 0.0000034129 0.0000087269
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0073
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.0186 0.0475
Trypanosoma brucei cation-transporting ATPase, putative 0.0026 0.0053 0.0755
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0057 0.0191 0.108
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.016 0.2257
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0006 0.0011
Schistosoma mansoni glutamate synthase 0.0014 0.0000034129 0.0000087269
Entamoeba histolytica hypothetical protein 0.0146 0.059 1
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0026 0.0053 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0005
Echinococcus granulosus dna polymerase kappa 0.0144 0.0577 0.1476
Echinococcus multilocularis chromobox protein 1 0.015 0.0606 0.1549
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0025 0.005 0.0069
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0088 0.0905
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0133 0.0341
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0018 0.009
Onchocerca volvulus 0.0056 0.0186 0.1905
Echinococcus multilocularis protoporphyrinogen oxidase 0.0025 0.005 0.0127
Schistosoma mansoni chromobox protein 0.0034 0.0088 0.0226
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0117 0.0459 0.1175
Schistosoma mansoni hypothetical protein 0.0401 0.1724 0.4408
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0093 0.035 0.4951
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.002 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0191 0.0334
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0036 0.0098 0.0171
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0577 0.1009
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0074 0.0268 0.1323
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0577 0.1009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Echinococcus multilocularis peroxidasin 0.0026 0.0053 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.0186 0.2995
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.005 0.0069
Echinococcus granulosus chromobox protein 1 0.015 0.0606 0.1549
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Giardia lamblia Myb 1-like protein 0.0051 0.0164 0.0808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0089 0.0914
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0093 0.0957
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0468 0.2024 0.7295
Giardia lamblia DINP protein human, muc B family 0.0124 0.049 0.242
Echinococcus multilocularis cysteine protease 0.0056 0.0186 0.0475
Leishmania major P-type H -ATPase, putative 0.0053 0.0172 0.2424
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Onchocerca volvulus 0.0233 0.0975 1
Brugia malayi Cathepsin L-like precursor 0.0022 0.0034 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0186 0.1906
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0174 0.2457
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0095 0.036 0.3692
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0174 0.0174
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0095 0.0243
Trichomonas vaginalis CMGC family protein kinase 0.005 0.016 0.1639
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0000034129 0.0000087269
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0308
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0115
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0261
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.002 0.0101
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0239 0.135
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0057 0.0191 0.0489
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.2951 0.7547
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0174 0.2457
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.0088 0.0905
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0115 0.0201
Schistosoma mansoni hypothetical protein 0.0146 0.059 0.1508
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0018 0.0046
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.0088 0.1422
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0117 0.0459 0.7407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0053 0.0547
Loa Loa (eye worm) hypothetical protein 0.0083 0.0306 0.151
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0277 0.0708
Treponema pallidum hypothetical protein 0.0017 0.0011 0.0011
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0014 0.0000034129 0.0000087269
Brugia malayi MH2 domain containing protein 0.039 0.1677 0.9475
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0186 0.0475
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Echinococcus granulosus cathepsin L 0.0018 0.0018 0.0046
Echinococcus multilocularis dna polymerase eta 0.0173 0.0708 0.1809
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0095 0.0244
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.035 0.1495 0.2088
Leishmania major calcium-translocating P-type ATPase 0.0117 0.0459 0.6493
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.0436
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0066 0.0232 0.1146
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Brugia malayi Cytochrome P450 family protein 0.0016 0.0006 0.0036
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0011 0.0019
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0076 0.0277 0.0708
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0359 0.1535 0.1535
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0001 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0175 0.0863
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0018 0.0293
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.0436
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0039 0.0039
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0163 0.1668
Plasmodium vivax cation transporting ATPase, putative 0.0026 0.0053 0.0861
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0065 0.0663
Echinococcus granulosus calcium transporting atpase 0.0101 0.0386 0.0987
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0023 0.006
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0139 0.1423
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0172 0.2424
Loa Loa (eye worm) hypothetical protein 0.0082 0.03 0.1484
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0163 0.2757
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0095 0.1613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Brugia malayi Pre-SET motif family protein 0.0205 0.0849 0.4798
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.2024 0.5175
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0239 0.0611
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0056 0.0187 0.1059
Echinococcus multilocularis cathepsin b 0.0018 0.0018 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0069 0.0706
Echinococcus multilocularis thioredoxin glutathione reductase 0.0153 0.062 0.1586
Loa Loa (eye worm) E1-E2 ATPase 0.0053 0.0172 0.0848
Schistosoma mansoni survival motor neuron protein 0.0047 0.0148 0.0378
Plasmodium vivax unspecified product 0.004 0.0115 0.1852
Trichomonas vaginalis MYB3r3, putative 0.0051 0.0163 0.1668
Schistosoma mansoni amine oxidase 0.0025 0.005 0.0127
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0025 0.005 0.0801
Schistosoma mansoni disulfide oxidoreductase 0.0014 0.0000034129 0.0000087269
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0095 0.0243
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0191 0.108
Brugia malayi Doublecortin family protein 0.0019 0.0023 0.0132
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0083 0.0306 0.5182
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0000034129 0.0000087269
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1622 0.7163 1
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0191 0.3081
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Mycobacterium ulcerans monoamine oxidase 0.0025 0.005 0.005
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0115 0.0294
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0046 0.0143 0.2423
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Entamoeba histolytica hypothetical protein 0.0034 0.0088 0.1496
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0232 0.0406
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0006 0.0006
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0066 0.0232 0.3278
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0095 0.0976
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0089 0.0914
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0061
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0089 0.1511
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0056 0.0142
Schistosoma mansoni chromobox protein 0.015 0.0606 0.1549
Schistosoma mansoni smad1 5 8 and 0.0027 0.0056 0.0142
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0072 0.0259
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.044
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0174 0.2803
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0093 0.1321
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Echinococcus multilocularis cathepsin L 0.004 0.0115 0.0294
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0144 0.0577 0.5921
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0057 0.0191 0.2701
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0649 0.1659
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma brucei chrX additional, unordered contigs 0.0036 0.01 0.1409
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0174 0.0445
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0115 0.1948
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0093 0.035 0.0896
Entamoeba histolytica hypothetical protein 0.0023 0.0039 0.0667
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0014 0.0000034129 0.0000087269
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0164 0.2646
Echinococcus multilocularis protein dispatched 1 0.0047 0.0148 0.0378
Schistosoma mansoni DNA helicase recq5 0.0019 0.002 0.0052
Schistosoma mansoni cathepsin s 0.0022 0.0034 0.0087
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0039 0.0142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.007 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0093 0.0957
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0018 0.0046
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0089 0.0504
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0115 0.1948
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0164 0.0287
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.03 0.1697
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.007 0.018
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0027
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.2024 0.5175
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0245
Plasmodium falciparum thioredoxin reductase 0.0153 0.062 1
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0277 0.0708
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.007 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0191 0.0334
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0327 0.4624
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0095 0.0166
Echinococcus granulosus lamin dm0 0.0026 0.0055 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.005 0.016 0.1639
Loa Loa (eye worm) calcium ATPase 0.0057 0.019 0.0937
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.01 0.1409
Echinococcus granulosus cathepsin l1 0.0034 0.0089 0.0228
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0088 0.1422
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0099 0.0562
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0133 0.0754
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Echinococcus multilocularis smad 0.0027 0.0056 0.0142
Onchocerca volvulus 0.0083 0.0306 0.3133
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0117 0.1197
Plasmodium vivax vivapain-2 0.0056 0.0186 0.2995
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Toxoplasma gondii melibiase subfamily protein 0.01 0.0385 0.1386
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.035 0.4951
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.044
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0053 0.0137
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0018 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0115 0.1179
Brugia malayi hypothetical protein 0.0025 0.005 0.0281
Brugia malayi MH1 domain containing protein 0.0027 0.0056 0.0315
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0351
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0018 0.0256
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0216 0.3051
Loa Loa (eye worm) hypothetical protein 0.0048 0.0153 0.0757
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0018 0.009
Onchocerca volvulus 0.0026 0.0053 0.0541
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0057 0.0191 0.2701
Mycobacterium ulcerans DNA polymerase IV 0.0144 0.0577 0.0577
Leishmania major DNA polymerase kappa, putative 0.0124 0.049 0.6921
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0117 0.1197
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0174 0.2803
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0386 0.0987
Loa Loa (eye worm) PDE1B protein 0.0057 0.0191 0.0944
Onchocerca volvulus 0.0026 0.0055 0.0564
Giardia lamblia Kinase, CMGC MAPK 0.005 0.016 0.0789
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0018 0.0293
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0093
Leishmania major cathepsin L-like protease 0.0056 0.0186 0.2626
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0167
Schistosoma mansoni hypothetical protein 0.004 0.0115 0.0294
Brugia malayi Peroxidasin 0.0026 0.0053 0.0298
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0018 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0186
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0239 0.0611
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0053 0.0264
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0264
Echinococcus granulosus geminin 0.0892 0.3911 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0063 0.0161
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0174 0.0304
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0633
Onchocerca volvulus 0.0122 0.0481 0.4931
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0139 0.0784
Leishmania major cytochrome p450-like protein 0.0016 0.0006 0.009
Mycobacterium tuberculosis Probable oxidoreductase 0.0389 0.1669 0.233
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Echinococcus multilocularis cpg binding protein 0.003 0.007 0.0178
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0053 0.0541
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0277 0.284
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0006 0.0031
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0076 0.0277 0.0708
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0164 0.1679
Loa Loa (eye worm) fibroinase 0.0056 0.0186 0.0918
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0163 0.1668
Trypanosoma brucei DNA polymerase IV, putative 0.0144 0.0577 0.8155
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0011 0.0039
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0026 0.0053 0.0075
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0057 0.0191 0.0334
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0018 0.0103
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0264
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0053 0.0137
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.097 0.2481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Loa Loa (eye worm) glutathione reductase 0.0153 0.062 0.3065
Schistosoma mansoni lipoxygenase 0.0054 0.0178 0.0456
Schistosoma mansoni intermediate filament proteins 0.0026 0.0055 0.0141
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0093 0.035 0.4951
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0272
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0000034129 0.0000087269
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0056 0.0187 0.0262
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0174 0.0243
Trichomonas vaginalis chromobox protein, putative 0.0095 0.036 0.3694
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0095 0.0976
Loa Loa (eye worm) hypothetical protein 0.0311 0.1323 0.6537
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Echinococcus multilocularis cation transporting ATPase 13A3 0.0026 0.0053 0.0137
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0411 0.177 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Echinococcus multilocularis neuropeptide s receptor 0.046 0.1985 0.5075
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0031
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0011 0.0019
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0088 0.1496
Schistosoma mansoni chromobox protein 0.0034 0.0088 0.0226
Echinococcus granulosus cpg binding protein 0.003 0.007 0.0178
Schistosoma mansoni rab6-interacting 0.0019 0.0023 0.006
Plasmodium vivax calcium-transporting ATPase, putative 0.0117 0.0459 0.7407
Schistosoma mansoni hypothetical protein 0.0892 0.3911 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0175 0.0986
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.0088 0.0226
Brugia malayi TAR-binding protein 0.0068 0.0239 0.135
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0083 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Loa Loa (eye worm) thioredoxin reductase 0.0153 0.062 0.3065
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0191 0.1961
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0174 0.0627
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.0429 0.075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.044
Brugia malayi Cathepsin L-like precursor 0.0056 0.0186 0.105
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0057 0.0191 0.0489
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.0304
Leishmania major DNA polymerase eta, putative 0.0092 0.0346 0.4896
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0148 0.0836
Plasmodium vivax thioredoxin reductase, putative 0.0153 0.062 1
Echinococcus multilocularis cysteine protease 0.0056 0.0186 0.0475
Loa Loa (eye worm) hypothetical protein 0.0053 0.0175 0.0863
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.005 0.0087
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0093 0.0957
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0334 0.3424
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.018 0.0648
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0088 0.0905
Trichomonas vaginalis C-MYB, putative 0.0051 0.0163 0.1668
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0057 0.0191 0.0334
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0011 0.0027
Plasmodium falciparum protoporphyrinogen oxidase 0.0025 0.005 0.0801
Trypanosoma brucei DNA polymerase IV, putative 0.0144 0.0577 0.8155
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0174 0.0445
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0174 0.2457
Schistosoma mansoni lipoxygenase 0.0019 0.0023 0.006
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0178 0.0456
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0115 0.0294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Brugia malayi Cathepsin L-like precursor 0.0034 0.0089 0.0504
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0011 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.005 0.016 0.0409
Schistosoma mansoni hypothetical protein 0.004 0.0115 0.0294
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0174 0.0859
Onchocerca volvulus 0.0056 0.0186 0.1905
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Onchocerca volvulus Cathepsin F homolog 0.0056 0.0186 0.1905
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.009
Trichomonas vaginalis CMGC family protein kinase 0.005 0.016 0.1639
Plasmodium vivax hypothetical protein, conserved 0.0025 0.005 0.0801
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0014 0.0000034129 0.0000087269
Loa Loa (eye worm) hypothetical protein 0.0046 0.0143 0.0706
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0018 0.0293
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0481 0.2717
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0000034129 0.0000087269
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0053 0.0906
Trichomonas vaginalis chromobox protein, putative 0.015 0.0606 0.6214
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0018 0.0186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Leishmania major cathepsin L-like protease 0.0056 0.0186 0.2626
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0174 0.0174
Echinococcus multilocularis geminin 0.0892 0.3911 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Leishmania major DNA polymerase kappa, putative 0.0036 0.01 0.1409
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0045 0.076
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0174 0.0304
Onchocerca volvulus 0.0019 0.0023 0.0239
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.016 0.0279
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0056 0.0187 0.0262
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0092 0.0346 0.1249
Treponema pallidum cation-transporting ATPase, P-type 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0057 0.0191 0.0489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Brugia malayi ImpB/MucB/SamB family protein 0.0118 0.0461 0.2605
Brugia malayi calcium ATPase 0.0036 0.0098 0.0554
Leishmania major copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0755
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.035 0.0613
Schistosoma mansoni type V p-type atpase isoform 0.0026 0.0053 0.0137
Plasmodium vivax unspecified product 0.0018 0.0018 0.0293
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0018 0.0103
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0039 0.0556
Echinococcus multilocularis chromobox protein 2 0.0034 0.0088 0.0226
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Loa Loa (eye worm) RecQ helicase 0.0045 0.0139 0.0685
Schistosoma mansoni hypothetical protein 0.004 0.0115 0.0294
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0245
Echinococcus granulosus Smad4 0.0027 0.0056 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.0025 0.0419
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0056 0.0275
Schistosoma mansoni DNA polymerase eta 0.0173 0.0708 0.1809
Schistosoma mansoni hypothetical protein 0.004 0.0115 0.0294
Giardia lamblia Hypothetical protein 0.0018 0.0018 0.009
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0239 0.118
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0034 0.0192
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0057 0.0191 0.0489
Onchocerca volvulus 0.0034 0.0089 0.0913
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0115 0.1948
Toxoplasma gondii cathepsin CPL 0.0056 0.0186 0.067
Giardia lamblia Copper-transporting P-type ATPase 0.0026 0.0053 0.0264
Trichomonas vaginalis cation-transporting ATPase, putative 0.0117 0.0459 0.4714
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0367 0.0939
Schistosoma mansoni lamin 0.0026 0.0055 0.0141
Schistosoma mansoni DNA polymerase IV / kappa 0.0036 0.01 0.0255
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0093 0.035 0.1263
Schistosoma mansoni alpha-glucosidase 0.0137 0.055 0.1406
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0117 0.1197
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0174 0.2803
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0088 0.0905
Loa Loa (eye worm) hypothetical protein 0.0117 0.0459 0.227
Schistosoma mansoni cpg binding protein 0.003 0.007 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0559
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0095 0.0976
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0036 0.0098 0.0353
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0386 0.0987
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0053 0.0541
Toxoplasma gondii P-type ATPase PMA1 0.0053 0.0172 0.0618
Loa Loa (eye worm) hypothetical protein 0.0173 0.0708 0.3497
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0095 0.0244
Echinococcus granulosus Chromo domain 0.0034 0.0088 0.0226
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Plasmodium vivax phosphodiesterase gamma, putative 0.0057 0.0191 0.3081
Schistosoma mansoni loxhd1 0.0019 0.0023 0.006
Brugia malayi Protein kinase domain containing protein 0.0015 0.0002 0.0011
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0039 0.0039
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0023 0.006
Schistosoma mansoni hypothetical protein 0.0023 0.0039 0.01
Onchocerca volvulus 0.0056 0.0186 0.1905
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0389 0.1669 0.233
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0026 0.0053 0.0075
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0056 0.0142
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0118 0.0461 0.2278
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.003 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0115 0.1179
Toxoplasma gondii histone lysine-specific demethylase 0.0025 0.005 0.0179
Onchocerca volvulus 0.0056 0.0186 0.1905
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0088 0.1422
Brugia malayi hypothetical protein 0.0017 0.0011 0.0061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0018 0.0293
Schistosoma mansoni copper ABC transporter ATPase 0.0026 0.0053 0.0137
Loa Loa (eye worm) hypothetical protein 0.0041 0.0122 0.0601
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0115 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0191 0.1961
Loa Loa (eye worm) helicase 0.0034 0.0088 0.0436
Schistosoma mansoni terminal deoxycytidyl transferase 0.0118 0.0461 0.1179
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.0088 0.0499
Onchocerca volvulus 0.0056 0.0186 0.1905
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0018 0.0293
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.059 0.1508
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0133 0.2264
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0163 0.2757
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0186 0.0325
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0101 0.104
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0146 0.059 1
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0172 0.176
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0174 0.0174
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0053 0.0541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0385 0.0983
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.0088 0.0499
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0333 0.1422 0.1986
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0133 0.1886
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.0088 0.0226
Mycobacterium ulcerans dehydrogenase 0.0025 0.005 0.005
Onchocerca volvulus 0.0122 0.0481 0.4931
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0003 0.0015
Plasmodium falciparum heterochromatin protein 1 0.0034 0.0088 0.1422
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0026 0.0053 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0191 0.0334
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0006 0.0031
Leishmania major DNA damage repair protein, putative 0.0036 0.01 0.1409
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0597 0.1044
Schistosoma mansoni lamin 0.0026 0.0055 0.0141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.0548 0.7748
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0095 0.0537
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0186
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.3081
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0239 0.0611
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0174 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0133 0.1369
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0003 0.0042
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0637 0.2774 0.2774
Trypanosoma brucei trypanothione reductase 0.0153 0.062 0.8766
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.2024 0.5175
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.2701
Brugia malayi RNA binding protein 0.0068 0.0239 0.135
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.0186 0.0918
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0018 0.0186
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0088 0.1496
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0026 0.0053 0.0137
Brugia malayi glutathione reductase 0.0153 0.062 0.3505
Echinococcus granulosus tumor protein p63 0.0331 0.1413 0.3613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0093 0.0957
Loa Loa (eye worm) hypothetical protein 0.0122 0.0481 0.2378
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0039 0.01
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0174 0.0445
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0095 0.047
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0006 0.0031
Leishmania major cathepsin L-like protease 0.0148 0.0597 0.8434
Entamoeba histolytica hypothetical protein 0.0034 0.0088 0.1496
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0057 0.0191 0.0334
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.3081
Leishmania major hypothetical protein, conserved 0.0051 0.0164 0.2319
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0053 0.0548
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0649 0.3206
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0298
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.01 0.1409
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.01 0.0359
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0221 0.0566
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0053 0.0541
Plasmodium falciparum calcium-transporting ATPase 0.0101 0.0386 0.6222
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0411 0.177 0.8745
Leishmania major proton motive ATPase, putative 0.0026 0.0053 0.0755
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0298
Brugia malayi hypothetical protein 0.0026 0.0053 0.0298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0236 0.0602
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0385 0.0983
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0334 0.3422
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Brugia malayi CHE-14 protein 0.0041 0.0122 0.0688
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0239 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0239 0.0611
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Giardia lamblia Hypothetical protein 0.0057 0.0191 0.0944
Brugia malayi hypothetical protein 0.0019 0.0023 0.0132
Plasmodium vivax unspecified product 0.0022 0.0034 0.0546
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.3081
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0006 0.0011
Trypanosoma brucei unspecified product 0.0081 0.0298 0.4216
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0026 0.0053 0.0053
Brugia malayi Blistered cuticle protein 3 0.0026 0.0053 0.0298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0115 0.1623
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0186 0.0475
Plasmodium falciparum glutathione reductase 0.0053 0.0174 0.2803
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Leishmania major cathepsin L-like protease 0.0056 0.0186 0.2626
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0018 0.0186
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0042
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0018 0.0293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0093 0.0957
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0191 0.0334
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0133 0.0233
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0066 0.0232 0.1146
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0411 0.177 0.4525
Trichomonas vaginalis MYB, putative 0.0051 0.0164 0.1679
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0164 0.2646
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.016 0.0279
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0577 0.1009
Brugia malayi Melibiase family protein 0.0067 0.0236 0.1331
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Brugia malayi fibroinase precursor 0.0018 0.0018 0.0103
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0014 0.0000034129 0.0000087269
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0012 0.007
Toxoplasma gondii cathepsin B 0.0018 0.0018 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0191 0.108
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0018 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0115 0.0201
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0055 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0191 0.1961
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0183 0.1874
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0389 0.1669 0.233
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.016 0.0279
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0115
Giardia lamblia Encystation-specific protease 0.0018 0.0018 0.009
Brugia malayi cathepsin L-like precursor 0.0034 0.0089 0.0504
Leishmania major cathepsin L-like protease 0.0148 0.0597 0.8434
Loa Loa (eye worm) hypothetical protein 0.0122 0.0481 0.2376
Onchocerca volvulus 0.0026 0.0053 0.0541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0441
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.0091 0.0127
Loa Loa (eye worm) hypothetical protein 0.0057 0.0191 0.0944
Brugia malayi amine oxidase, flavin-containing family protein 0.0025 0.005 0.0281
Schistosoma mansoni cathepsin C 0.0018 0.0018 0.0046
Schistosoma mansoni smad1 5 8 and 0.0027 0.0056 0.0142
Loa Loa (eye worm) hypothetical protein 0.0468 0.2024 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0186 0.0475
Trypanosoma cruzi cruzipain precursor, putative 0.0148 0.0597 0.1044
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Brugia malayi SWIRM domain containing protein 0.0025 0.005 0.0281
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0057 0.0191 0.0334
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0000034129 0.0000087269
Onchocerca volvulus 0.0026 0.0053 0.0541
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0011 0.0039
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.005 0.0127
Schistosoma mansoni rab6-interacting 0.0019 0.0023 0.006
Onchocerca volvulus Huntingtin homolog 0.012 0.0472 0.4844
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0104 0.1062
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0053 0.0906
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0559
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0025 0.005 0.0801
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0018 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0327 0.4624
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0057 0.0191 0.0489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0088 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Loa Loa (eye worm) hypothetical protein 0.0051 0.0163 0.0807
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.002 0.0052
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0122 0.0311
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.059 0.1508
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0039 0.0634
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0164 0.2646
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0088 0.0905
Echinococcus granulosus cathepsin L 0.004 0.0115 0.0294
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0216 0.3051
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0018 0.0032
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.01 0.1409
Loa Loa (eye worm) cysteine protease 0.0056 0.0186 0.0918
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0122 0.1249
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0183 0.1874
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0095 0.0244
Onchocerca volvulus 0.0026 0.0055 0.0564
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0027 0.0057 0.0207
Loa Loa (eye worm) RNA binding protein 0.0068 0.0239 0.118
Brugia malayi cathepsin L precursor 0.0018 0.0018 0.0103
Mycobacterium ulcerans oxidoreductase 0.0025 0.005 0.005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0095 0.0976
Leishmania major calcium-transporting ATPase, putative 0.0066 0.0232 0.3278
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Chlamydia trachomatis protoporphyrinogen oxidase 0.0025 0.005 0.005
Echinococcus multilocularis 0.0025 0.005 0.0127
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0115 0.0649
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0057 0.0191 0.108
Schistosoma mansoni cation-transporting ATPase 0.0026 0.0053 0.0137
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.005 0.0801
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0649 0.3666
Onchocerca volvulus 0.0025 0.005 0.0509
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.01 0.0174
Entamoeba histolytica deoxycytidyl transferase, putative 0.0118 0.0461 0.7818
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0186
Echinococcus granulosus chromobox protein 1 0.015 0.0606 0.1549
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0101 0.0386 0.0987
Echinococcus multilocularis Smad4 0.0027 0.0056 0.0142
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.03 0.0768
Brugia malayi Na,K-ATPase alpha subunit 0.0083 0.0306 0.1726
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0013
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0027
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0374 0.0956
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1622 0.7163 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0117 0.1197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Brugia malayi MH2 domain containing protein 0.0027 0.0056 0.0315
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0018 0.0293
Chlamydia trachomatis metal transport ATPase 0.0026 0.0053 0.0053
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0051 0.0254
Schistosoma mansoni alpha-glucosidase 0.0137 0.055 0.1406
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0057 0.0191 0.0489
Plasmodium vivax copper-transporting ATPase, putative 0.0026 0.0053 0.0861
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0191 0.0334
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0031
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.035 0.1495 0.2088
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0057 0.0191 0.2701
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0057 0.0191 0.0489
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Brugia malayi hypothetical protein 0.0232 0.097 0.5482
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0186 0.3151
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0115 0.0201
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0124 0.049 0.6921
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0163 0.1668
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0065 0.0225 0.0394
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0066 0.0232 0.0593
Brugia malayi ImpB/MucB/SamB family protein 0.0173 0.0708 0.3999
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0018 0.0293
Echinococcus granulosus dna polymerase eta 0.0173 0.0708 0.1809
Echinococcus granulosus glutamate synthase 0.0014 0.0000034129 0.0000087269
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0055 0.0272
Plasmodium falciparum phosphodiesterase gamma, putative 0.0057 0.0191 0.3081
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0034 0.0192
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0101
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0057 0.0191 0.0489
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0191 0.1961
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0018 0.0293
Schistosoma mansoni alpha glucosidase 0.0035 0.0095 0.0243
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0117 0.0459 0.1175
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0003 0.0017
Schistosoma mansoni ATPase 0.0117 0.0459 0.1175
Trypanosoma brucei unspecified product 0.0081 0.0298 0.4216
Trypanosoma cruzi cation-transporting ATPase, putative 0.0026 0.0053 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0133 0.066
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0239 0.118
Plasmodium vivax DNA repair protein REV1, putative 0.0036 0.01 0.1608
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.03 0.0768
Trypanosoma cruzi DNA polymerase eta, putative 0.0173 0.0708 0.1237
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.002 0.0101
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0093 0.035 0.0896
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.012 0.0472 0.2334
Loa Loa (eye worm) hypothetical protein 0.0056 0.0186 0.0918
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.002 0.0052
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0018 0.0293
Brugia malayi Heterochromatin protein 1 0.015 0.0606 0.3422
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0005
Echinococcus granulosus tar DNA binding protein 0.0068 0.0239 0.0611
Trypanosoma brucei protein kinase, putative 0.005 0.016 0.2257
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.0114 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0191 0.0334
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0014 0.0000034129 0.0000087269
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Brugia malayi E1-E2 ATPase family protein 0.0053 0.0172 0.097
Schistosoma mansoni ATPase 0.0117 0.0459 0.1175
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0025 0.005 0.0127
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0174 0.2457
Schistosoma mansoni hypothetical protein 0.0892 0.3911 1
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0057 0.0191 0.0489
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.035 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0105 0.1075
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0088 0.0318
Brugia malayi SET domain containing protein 0.0036 0.0096 0.0541
Trichomonas vaginalis cation-transporting ATPase, putative 0.0117 0.0459 0.4714
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0115 0.0649
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Loa Loa (eye worm) hypothetical protein 0.0051 0.0164 0.0811
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0023 0.006
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0025 0.005 0.0127
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Onchocerca volvulus Peroxidase homolog 0.0026 0.0053 0.0541
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Echinococcus multilocularis X box binding protein 1 0.0282 0.1196 0.3057
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.3595
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0552 0.1411
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0637 0.2774 1
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0036 0.0098 0.0484
Trichomonas vaginalis chromobox protein, putative 0.015 0.0606 0.6214
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.3595
Trichomonas vaginalis chromobox protein, putative 0.0095 0.036 0.3694
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0018 0.0293
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0026 0.0053 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0053 0.0547
Brugia malayi hypothetical protein 0.0122 0.0481 0.272
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0468 0.2024 0.5175
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0063 0.0309
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0055 0.0311
Echinococcus multilocularis cation transporting atpase worm 0.0026 0.0053 0.0137
Brugia malayi Cathepsin L-like precursor 0.0056 0.0186 0.105
Entamoeba histolytica cysteine proteinase 2 0.004 0.0115 0.1948
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0036 0.0098 0.0171
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0018 0.0308
Entamoeba histolytica hypothetical protein 0.0034 0.0088 0.1496
Plasmodium falciparum glutathione reductase 0.0153 0.062 1
Schistosoma mansoni smad1 5 8 and 0.0027 0.0056 0.0142
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0018 0.0293
Echinococcus granulosus cation transporting atpase worm 0.0026 0.0053 0.0137
Mycobacterium ulcerans hypothetical protein 0.0036 0.01 0.01
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Brugia malayi CXXC zinc finger family protein 0.0028 0.0063 0.0354
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0025 0.005 0.0801
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0174 0.0627
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0411 0.177 0.4525
Loa Loa (eye worm) hypothetical protein 0.0057 0.0191 0.0944
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0104 0.1062
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0133 0.1369
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0133 0.0341
Loa Loa (eye worm) cathepsin B 0.0018 0.0018 0.009
Brugia malayi Smad1 0.0027 0.0056 0.0315
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0011 0.0027
Leishmania major cathepsin L-like protease 0.0148 0.0597 0.8434
Echinococcus multilocularis glutamate synthase 0.0014 0.0000034129 0.0000087269
Entamoeba histolytica hypothetical protein 0.0018 0.0018 0.0308
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0186 0.3151
Trichomonas vaginalis pc-MYB2, putative 0.0051 0.0163 0.1668
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0174 0.2803
Brugia malayi hypothetical protein 0.0146 0.059 0.3331
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0385 0.0983
Schistosoma mansoni patched 1 0.0041 0.0122 0.0311
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.0606 0.2992
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.2951 0.7547
Brugia malayi Pre-SET motif family protein 0.003 0.007 0.0397
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.0186 0.105
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0095 0.0343
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0468 0.2024 1
Echinococcus granulosus chromobox protein 2 0.0034 0.0088 0.0226
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0191 0.0334
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0191 0.108
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0186 0.1905
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0164 0.2319
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0245
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0385 0.0983
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0259 0.0662
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0597 0.1044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Onchocerca volvulus Peroxidase homolog 0.0026 0.0053 0.0541
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.5943
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0096 0.0246
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0083 0.0306 0.0781
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0236 0.0602
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0441
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.016 0.0409
Leishmania major hypothetical protein, conserved 0.0057 0.0191 0.2701
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0103
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0117 0.0459 0.1175
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.007 0.018
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0018 0.0046
Echinococcus granulosus X box binding protein 1 0.0282 0.1196 0.3057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0039 0.0039
Plasmodium vivax vivapain-2 0.0056 0.0186 0.2995
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0117 0.0459 0.1656
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0039 0.0142
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0367 0.6229
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0245
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0018 0.0103
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.0186 0.0918
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0298
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0014 0.0000034129 0.0000087269
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.007 0.018
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0308
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Onchocerca volvulus 0.0056 0.0186 0.1905
Echinococcus granulosus expressed conserved protein 0.0091 0.0341 0.0872
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0145 0.0818
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0186 0.1906
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.0114 0.1608
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0849 0.4195
Trypanosoma cruzi cysteine protease, putative 0.004 0.0115 0.0201
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Plasmodium vivax P-type ATPase4, putative 0.0117 0.0459 0.7407
Schistosoma mansoni hypothetical protein 0.0282 0.1196 0.3057
Giardia lamblia GTOR 0.0044 0.0133 0.066
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0175 0.0986
Loa Loa (eye worm) MH2 domain-containing protein 0.039 0.1677 0.8286
Giardia lamblia Hypothetical protein 0.0018 0.0018 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0073
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0026 0.0053 0.0302
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0023 0.0375
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0308
Entamoeba histolytica hypothetical protein 0.0146 0.059 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0111 0.0628
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0163 0.1668
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.098 0.4843
Brugia malayi chromobox protein homolog 3 0.0089 0.0334 0.1886
Schistosoma mansoni peroxidasin 0.0026 0.0053 0.0135
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0163 0.1668
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0023 0.0375
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2259 1 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0018 0.0046
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0264
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0023 0.006
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0637 0.2774 0.3873
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.0088 0.0318
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.002 0.0328
Onchocerca volvulus 0.0056 0.0186 0.1905
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0093 0.1321
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0057 0.019 0.3215
Leishmania major cathepsin L-like protease 0.0056 0.0186 0.2626
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0095 0.0976
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Loa Loa (eye worm) hypothetical protein 0.012 0.0472 0.2334
Plasmodium vivax glutathione reductase, putative 0.0153 0.062 1
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.033 0.0843
Mycobacterium tuberculosis Probable reductase 0.035 0.1495 0.2088
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0025 0.005 0.0127
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0174 0.0983
Echinococcus granulosus copper transporting ATPase 1 0.0026 0.0053 0.0137
Trypanosoma brucei DNA polymerase eta, putative 0.0173 0.0708 1
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0026 0.0053 0.0548
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0018 0.0293
Trichomonas vaginalis C-MYB, putative 0.0051 0.0163 0.1668
Schistosoma mansoni smad 0.0027 0.0056 0.0142
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0073 0.1183
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Brugia malayi Cathepsin L-like precursor 0.0056 0.0186 0.105
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0088 0.0226
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.0304
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0039 0.0055
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0057 0.0191 0.108
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0018 0.0293
Schistosoma mansoni hypothetical protein 0.0036 0.0099 0.0254
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0088 0.0226
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.2457
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0115
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0018 0.009
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0039 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.049 0.6921
Echinococcus multilocularis expressed conserved protein 0.0091 0.0341 0.0872
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.016 0.0279
Echinococcus granulosus cysteine protease 0.004 0.0115 0.0294
Schistosoma mansoni peroxidasin 0.0026 0.0053 0.0135
Brugia malayi E1-E2 ATPase family protein 0.0026 0.0053 0.0302
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0051 0.0163 0.2757
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0012 0.007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0174 0.0174
Brugia malayi MH1 domain containing protein 0.0027 0.0056 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Schistosoma mansoni hypothetical protein 0.0014 0.0000034129 0.0000087269
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0018 0.0293
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0018 0.0293
Echinococcus granulosus dnaJ subfamily B 0.0401 0.1724 0.4408
Leishmania major trypanothione reductase 0.0153 0.062 0.8766
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0367 0.0939
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0186 0.1906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0011 0.0027
Brugia malayi Cathepsin L-like precursor 0.0034 0.0089 0.0504
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0026 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0118 0.0461 0.1179
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0236 0.2417
Leishmania major UDP-galactopyranose mutase 0.0025 0.005 0.0702
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.0304
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0153 0.0392
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0308
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0118 0.0461 0.1179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0089 0.0228
Loa Loa (eye worm) hypothetical protein 0.0067 0.0236 0.1164
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0637 0.2774 0.2774
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0232 0.0406
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Trichomonas vaginalis cation-transporting ATPase, putative 0.0093 0.035 0.3595
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0036 0.0098 0.0554
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0083 0.0306 0.151
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0057 0.0191 0.2701
Echinococcus granulosus cathepsin b 0.0018 0.0018 0.0046
Echinococcus granulosus bloom syndrome protein 0.0045 0.0139 0.0355
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0095 0.0976
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0018 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.005 0.016 0.1639
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.0436
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0174 0.2457
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0115
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0298
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0056 0.0142
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.01 0.0174
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0018 0.0046
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0018 0.0046
Loa Loa (eye worm) nuclear factor I 0.0015 0.0003 0.0013
Trichomonas vaginalis MYB72, putative 0.0051 0.0163 0.1668
Plasmodium falciparum thioredoxin reductase 0.0053 0.0174 0.2803
Leishmania major DNA polymerase eta, putative 0.0173 0.0708 1
Schistosoma mansoni polycystin 1-related 0.0019 0.0023 0.006
Echinococcus granulosus smad 0.0027 0.0056 0.0142
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0011 0.0039
Brugia malayi hypothetical protein 0.0051 0.0164 0.0927
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0083 0.0853
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0389 0.1669 0.233
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.1033
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0191 0.0489
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0577 0.1009
Echinococcus granulosus intermediate filament protein 0.0026 0.0055 0.0141
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.3081
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0095 0.0976
Schistosoma mansoni glutamate synthase 0.0014 0.0000034129 0.0000087269
Giardia lamblia Cathepsin L-like protease 0.0018 0.0018 0.009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0261
Leishmania major cysteine peptidase A (CPA) 0.0056 0.0186 0.2626
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0026 0.0053 0.0053
Echinococcus granulosus cathepsin b 0.0018 0.0018 0.0046
Trypanosoma cruzi DNA polymerase eta, putative 0.0092 0.0346 0.0606
Trypanosoma cruzi P-type H+-ATPase, putative 0.0036 0.0098 0.0171
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0259 0.0662
Brugia malayi MAP kinase sur-1 0.005 0.016 0.0903
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.5943
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0095 0.1344
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0014 0.0000034129 0.0000087269
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0018 0.0293
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0006 0.009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0034 0.0167
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0117 0.1197
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.0304
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0026 0.0053 0.0053
Loa Loa (eye worm) transcription factor SMAD2 0.039 0.1677 0.8286
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.016 0.0409
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0039 0.0556
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0003 0.0042
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0117 0.0459 0.0803
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0018 0.0186
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Echinococcus granulosus RUN 0.0019 0.0023 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.005 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.016 0.2257
Loa Loa (eye worm) hypothetical protein 0.0057 0.0191 0.0944
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0056 0.0187 0.0187
Loa Loa (eye worm) ctsf protein 0.0056 0.0186 0.0918
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.033 0.0843
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0051 0.0164 0.059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0186 0.1906
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0164 0.0287
Echinococcus multilocularis Chromo domain 0.0034 0.0088 0.0226
Echinococcus multilocularis Chromobox protein 3 0.0034 0.0088 0.0226
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0178 0.0456
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0117 0.1197
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0026 0.0053 0.0906
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0095 0.0471
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.035 0.1495 0.2088
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0133 0.2264
Echinococcus granulosus mitogen activated protein kinase 0.005 0.016 0.0409
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0039 0.0055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0117 0.1197
Plasmodium vivax hypothetical protein, conserved 0.0025 0.005 0.0801
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0385 0.0983
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0018 0.0308
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0261
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0117 0.0459 0.1175
Schistosoma mansoni hypothetical protein 0.0034 0.0088 0.0226
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0174 0.0174
Echinococcus granulosus neuropeptide receptor A26 0.046 0.1985 0.5075
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0191 0.0334
Schistosoma mansoni Smad4 0.0027 0.0056 0.0142
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0191 0.0689
Trypanosoma cruzi cruzipain precursor, putative 0.1298 0.5719 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0191 0.1961
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0597 0.8434
Trypanosoma brucei unspecified product 0.0137 0.0548 0.7748
Brugia malayi Cathepsin L-like precursor 0.0056 0.0186 0.105
Onchocerca volvulus 0.0061 0.0209 0.2143
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.0461 0.0643
Echinococcus multilocularis cathepsin b 0.0018 0.0018 0.0046
Echinococcus multilocularis copper transporting ATPase 1 0.0026 0.0053 0.0137
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0051 0.0163 0.1668
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0186
Loa Loa (eye worm) hypothetical protein 0.005 0.0159 0.0784
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.0186 0.2995
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0088 0.0905
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.007 0.018
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0053 0.0261
Leishmania major cAMP-specific phosphodiesterase, putative 0.0057 0.0191 0.2701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0133 0.1369
Onchocerca volvulus 0.0082 0.03 0.308
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.1034
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0001
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0649 0.1659
Onchocerca volvulus 0.0092 0.0349 0.3577
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0103
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0153 0.062 0.0866
Plasmodium vivax vivapain-3 0.004 0.0115 0.1852
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0164 0.0592
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0053 0.0548
Entamoeba histolytica hypothetical protein 0.0146 0.059 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0186 0.0475
Echinococcus multilocularis tumor protein p63 0.0331 0.1413 0.3613
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0056 0.0142
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0118 0.0461 0.1179
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0026 0.0053 0.0302
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.1961
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0597 0.1044
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0133 0.1886
Leishmania major calcium motive p-type ATPase, putative 0.0066 0.0232 0.3278
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0057 0.0191 0.0489
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.2024 0.5175
Loa Loa (eye worm) hypothetical protein 0.0139 0.0557 0.275
Loa Loa (eye worm) calcium ATPase 0.002 0.0025 0.0122
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0367 0.2075
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0088 0.1496
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0088 0.0905
Toxoplasma gondii thioredoxin reductase 0.0153 0.062 0.2236
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0191 0.2701
Mycobacterium tuberculosis Probable dehydrogenase 0.035 0.1495 0.2088
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.3595
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0174 0.0304
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0095 0.1613
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0016
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0018 0.0046
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0103
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0139 0.1423
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0018 0.0293
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0078
Entamoeba histolytica cysteine protease, putative 0.004 0.0115 0.1948
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0000034129 0.0000087269
Brugia malayi Cytochrome P450 family protein 0.0016 0.0006 0.0036
Entamoeba histolytica cysteine protease, putative 0.0056 0.0186 0.3151
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0053 0.0906
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0057 0.0191 0.0944
Echinococcus multilocularis calcium transporting atpase 0.0101 0.0386 0.0987
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0088 0.0905
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0095 0.0976
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0649 0.1659
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0261
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.005 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0117 0.1197
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.0436
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0046
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0172 0.03
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0174 0.1784
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0018 0.0293
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0012 0.0061
Brugia malayi Cathepsin L-like precursor 0.0056 0.0186 0.105
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0577 0.8155
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0273
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.0088 0.1422
Trypanosoma brucei glucosidase, putative 0.0035 0.0095 0.1344
Trichomonas vaginalis hypothetical protein 0.0034 0.0088 0.0905
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0093
Echinococcus multilocularis GPCR, family 2 0.0017 0.0012 0.0031
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.009
Onchocerca volvulus 0.0019 0.0023 0.0239
Toxoplasma gondii P-type ATPase4, putative 0.0083 0.0306 0.1101
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2259 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0191 0.2701
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.035 0.5943
Echinococcus granulosus peroxidasin 0.0026 0.0053 0.0135
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0261
Loa Loa (eye worm) hypothetical protein 0.003 0.007 0.0347

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.007 uM Inhibitory concentration against monoamine oxidase A. ChEMBL. 9622553
IC50 (binding) = 0.007 uM Inhibitory concentration against monoamine oxidase A. ChEMBL. 9622553
Inhibition (binding) = 0 % Compound was evaluated for percent inhibition against Monoamine oxidase B at 0.01 microM concentration ChEMBL. 9622553
Inhibition (binding) = 0 % Compound was evaluated for percent inhibition against Monoamine oxidase B at 0.01 microM concentration ChEMBL. 9622553

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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