Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.016 | 0.0752 | 0.6326 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.016 | 0.0752 | 0.6326 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0163 | 0.0772 | 0.137 |
Trichomonas vaginalis | ran, putative | 0.007 | 0.024 | 0.0969 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0031 | 0.0022 | 0.0014 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0148 | 0.0687 | 0.1206 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0085 | 0.0077 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0191 | 0.2515 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0081 | 0.0305 | 0.4037 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0066 | 0.0218 | 0.021 |
Echinococcus granulosus | geminin | 0.0854 | 0.4687 | 0.4682 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0148 | 0.0687 | 0.2772 |
Leishmania major | importin beta-1 subunit, putative | 0.0077 | 0.028 | 0.1414 |
Brugia malayi | RNA, U transporter 1 | 0.0269 | 0.137 | 0.1361 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0039 | 0.0066 | 0.0111 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0144 | 0.0135 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.028 | 0.5244 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0095 | 0.0382 | 0.2028 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0119 | 0.0111 |
Echinococcus multilocularis | dnaJ subfamily B | 0.171 | 0.9541 | 0.9541 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0158 | 0.0744 | 0.1315 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0246 | 0.1238 | 0.129 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0077 | 0.028 | 0.1131 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0492 | 1 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0144 | 0.0136 |
Mycobacterium tuberculosis | Conserved protein | 0.0148 | 0.0687 | 0.1206 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0144 | 0.0135 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0408 | 0.2161 | 0.2153 |
Onchocerca volvulus | 0.016 | 0.0751 | 0.2967 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0148 | 0.0687 | 0.2772 |
Echinococcus granulosus | peregrin | 0.0064 | 0.021 | 0.0202 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0085 | 0.0075 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0231 | 0.0234 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0108 | 0.01 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0131 | 0.0591 | 0.4512 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.2526 | 0.2641 |
Mycobacterium leprae | conserved hypothetical protein | 0.0148 | 0.0687 | 0.5034 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0164 | 0.0155 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0094 | 0.0377 | 0.0369 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0031 | 0.0022 | 0.0013 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0136 | 0.0126 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0047 | 0.0039 |
Leishmania major | hypothetical protein, conserved | 0.0148 | 0.0687 | 0.388 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0039 | 0.0069 | 0.006 |
Brugia malayi | ecdysteroid receptor | 0.0066 | 0.0218 | 0.0209 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0047 | 0.0191 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0066 | 0.0218 | 0.0209 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0108 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0119 | 0.0109 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0081 | 0.0305 | 0.1561 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0066 | 0.0218 | 0.0209 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0039 | 0.0066 | 0.0057 |
Schistosoma mansoni | transient receptor potential channel | 0.0064 | 0.0209 | 0.0211 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.0233 | 0.0235 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0056 | 0.0164 | 0.0191 |
Mycobacterium tuberculosis | Conserved protein | 0.0049 | 0.0125 | 0.0115 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0158 | 0.0744 | 0.1315 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0032 | 0.0027 | 0.0019 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0077 | 0.0284 | 0.0289 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0066 | 0.0218 | 0.021 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0215 | 0.1064 | 0.1055 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0173 | 0.0829 | 0.656 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 1 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0051 | 0.0137 | 0.0138 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0066 | 0.0218 | 0.021 |
Brugia malayi | Bromodomain containing protein | 0.0064 | 0.021 | 0.02 |
Brugia malayi | CXXC zinc finger family protein | 0.012 | 0.0526 | 0.0517 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0055 | 0.0158 | 0.0193 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0108 | 0.0098 |
Brugia malayi | AMP-binding enzyme family protein | 0.016 | 0.0751 | 0.0741 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0215 | 0.1064 | 0.1055 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.0213 | 0.0205 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0105 | 0.044 | 0.0431 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0148 | 0.0687 | 0.2772 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0148 | 0.0687 | 0.388 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0066 | 0.0218 | 0.022 |
Onchocerca volvulus | 0.0066 | 0.0218 | 0.0801 | |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.0403 | 0.0395 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0066 | 0.0218 | 0.0209 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0031 | 0.0022 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0093 | 0.0372 | 0.0595 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0066 | 0.0218 | 0.022 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0066 | 0.0218 | 0.0209 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0086 | 0.0334 | 0.0326 |
Echinococcus multilocularis | peregrin | 0.0064 | 0.021 | 0.0202 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.037 | 0.0361 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0035 | 0.0043 | 0.0036 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0066 | 0.0218 | 0.0209 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0039 | 0.0066 | 0.0057 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0041 | 0.0078 | 0.0188 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.019 | 0.0924 | 0.0916 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.016 | 0.0752 | 0.5624 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0057 | 0.0047 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0062 | 0.0197 | 0.0189 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0064 | 0.0209 | 0.0201 |
Plasmodium vivax | hypothetical protein, conserved | 0.0148 | 0.0687 | 0.9139 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0064 | 0.0209 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0235 | 0.0225 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0022 | 0.0012 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.031 | 0.1601 | 0.1593 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0041 | 0.0078 | 0.0188 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0144 | 0.0135 |
Mycobacterium ulcerans | polyketide synthase | 0.0173 | 0.0829 | 0.656 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0948 | 0.522 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0114 | 0.0492 | 0.0507 |
Brugia malayi | hypothetical protein | 0.0114 | 0.0492 | 0.0482 |
Brugia malayi | Importin beta-1 subunit | 0.0095 | 0.0382 | 0.0372 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0068 | 0.0231 | 0.0222 |
Echinococcus granulosus | cpg binding protein | 0.0129 | 0.0576 | 0.0568 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.0403 | 0.0395 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0039 | 0.0069 | 0.006 |
Echinococcus granulosus | tar DNA binding protein | 0.0473 | 0.2526 | 0.252 |
Brugia malayi | jmjC domain containing protein | 0.0203 | 0.0996 | 0.0987 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0041 | 0.0078 | 0.0188 |
Mycobacterium ulcerans | hypothetical protein | 0.0172 | 0.082 | 0.6483 |
Schistosoma mansoni | transient receptor potential channel | 0.0097 | 0.0395 | 0.0406 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0257 | 0.1302 | 0.1357 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0031 | 0.0022 | 0.0013 |
Schistosoma mansoni | lipoxygenase | 0.0054 | 0.0153 | 0.0152 |
Echinococcus multilocularis | geminin | 0.0854 | 0.4687 | 0.4682 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0215 | 0.1064 | 0.1055 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.0754 | 0.0746 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0085 | 0.0077 |
Schistosoma mansoni | hypothetical protein | 0.0854 | 0.4687 | 0.4908 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.007 | 0.024 | 0.117 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0051 | 0.0137 | 0.0611 |
Schistosoma mansoni | hypothetical protein | 0.1009 | 0.5567 | 0.5831 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0049 | 0.0125 | 0.0115 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0066 | 0.0218 | 0.022 |
Echinococcus multilocularis | muscleblind protein 1 | 0.1791 | 1 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0326 | 0.1696 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0144 | 0.0136 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0047 | 0.0191 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0246 | 0.1238 | 0.129 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0064 | 0.0209 | 0.0201 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0076 | 0.0071 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0108 | 0.0104 |
Plasmodium vivax | hypothetical protein, conserved | 0.0062 | 0.0197 | 0.2599 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0382 | 0.0372 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0066 | 0.0111 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0022 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0076 | 0.0071 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0041 | 0.0078 | 0.0109 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0108 | 0.0352 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0054 | 0.0153 | 0.0145 |
Brugia malayi | Pre-SET motif family protein | 0.0408 | 0.2161 | 0.2153 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0108 | 0.0098 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0097 | 0.0395 | 0.0387 |
Loa Loa (eye worm) | hypothetical protein | 0.0275 | 0.1407 | 0.1399 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0066 | 0.0218 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.1064 | 0.1055 |
Brugia malayi | Transient-receptor-potential like protein | 0.0036 | 0.005 | 0.004 |
Mycobacterium ulcerans | polyketide synthase | 0.0163 | 0.0772 | 0.6066 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.007 | 0.024 | 0.3177 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0127 | 0.0565 | 0.0555 |
Plasmodium vivax | importin-beta 2, putative | 0.0095 | 0.0382 | 0.5065 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.007 | 0.024 | 0.0232 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0036 | 0.0052 | 0.0043 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.007 | 0.024 | 0.0231 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0114 | 0.0492 | 0.0507 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0039 | 0.0066 | 0.0411 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0041 | 0.0078 | 0.0278 |
Brugia malayi | conserved hypotetical protein | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0108 | 0.0458 | 0.3372 |
Schistosoma mansoni | transient receptor potential channel | 0.0064 | 0.0209 | 0.0211 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0191 | 0.0191 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0047 | 0.0191 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0108 | 0.01 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0031 | 0.0022 | 0.0014 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0031 | 0.0022 | 0.0013 |
Trichomonas vaginalis | importin beta-1, putative | 0.0077 | 0.028 | 0.1131 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0687 | 0.0678 |
Schistosoma mansoni | cpg binding protein | 0.012 | 0.0526 | 0.0543 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0085 | 0.0077 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.007 | 0.024 | 0.0232 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0066 | 0.022 | 0.03 |
Onchocerca volvulus | 0.0093 | 0.0371 | 0.1422 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0246 | 0.1238 | 0.1231 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0041 | 0.0078 | 0.0109 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0032 | 0.0027 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.0403 | 0.8012 |
Trichomonas vaginalis | set domain proteins, putative | 0.0464 | 0.2479 | 1 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0041 | 0.0078 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0395 | 0.0386 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0041 | 0.0078 | 0.1017 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0244 | 0.123 | 0.2259 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0066 | 0.0218 | 0.022 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0131 | 0.0591 | 0.4155 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.016 | 0.0751 | 0.1329 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0246 | 0.1238 | 0.1231 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0191 | 0.0181 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0163 | 0.0772 | 0.6066 |
Onchocerca volvulus | Alhambra homolog | 0.0062 | 0.0197 | 0.0713 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0055 | 0.0158 | 0.2079 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.016 | 0.0752 | 1 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0036 | 0.005 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0066 | 0.0218 | 0.0209 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0047 | 0.0191 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0035 | 0.0043 | 0.0034 |
Echinococcus granulosus | GPCR family 2 | 0.0068 | 0.0231 | 0.0223 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0148 | 0.0687 | 0.1206 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.2526 | 0.2641 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0084 | 0.032 | 0.0311 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0077 | 0.028 | 0.1414 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0417 | 0.0408 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0108 | 0.0098 |
Mycobacterium ulcerans | hypothetical protein | 0.0148 | 0.0687 | 0.5337 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0064 | 0.0209 | 0.0201 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.016 | 0.0754 | 0.0746 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0066 | 0.0218 | 0.0801 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0066 | 0.0218 | 0.021 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0066 | 0.0218 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0231 | 0.0222 |
Leishmania major | hypothetical protein, conserved | 0.0081 | 0.0305 | 0.1561 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0066 | 0.0847 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0116 | 0.0505 | 0.4112 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | MH2 domain containing protein | 0.0127 | 0.0565 | 0.0555 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0076 | 0.0071 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.007 | 0.024 | 0.0231 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0031 | 0.0022 | 0.0012 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0094 | 0.0377 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.007 | 0.006 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0066 | 0.0218 | 0.021 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0066 | 0.0218 | 0.021 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0127 | 0.0565 | 0.0555 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.016 | 0.0751 | 0.0741 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 0.5892 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0022 | 0.0012 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.016 | 0.0754 | 0.0745 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0225 | 0.1123 | 0.1114 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0148 | 0.0687 | 0.0712 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.019 | 0.0924 | 0.0916 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0097 | 0.0395 | 0.0387 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0041 | 0.0078 | 0.1017 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0114 | 0.0492 | 0.0484 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0066 | 0.0218 | 0.0209 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0043 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.171 | 0.9541 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.1791 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0066 | 0.0218 | 0.0209 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0084 | 0.032 | 0.0312 |
Schistosoma mansoni | cpg binding protein | 0.0129 | 0.0576 | 0.0595 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.0754 | 0.0746 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0076 | 0.0071 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.037 | 0.0361 |
Onchocerca volvulus | 0.0046 | 0.0108 | 0.0352 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0246 | 0.1238 | 0.123 |
Mycobacterium ulcerans | thioesterase TesA | 0.0136 | 0.0618 | 0.4741 |
Schistosoma mansoni | methyltransferase-related | 0.0049 | 0.0125 | 0.0122 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.004 | 0.0072 | 0.0013 |
Toxoplasma gondii | ABC1 family protein | 0.0148 | 0.0687 | 0.5746 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Onchocerca volvulus | 0.0101 | 0.0417 | 0.1611 | |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0041 | 0.0078 | 0.0185 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0687 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0197 | 0.0187 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0473 | 0.2526 | 0.2519 |
Brugia malayi | ecdysone receptor | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0173 | 0.0829 | 0.6337 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0246 | 0.1238 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0147 | 0.0679 | 0.067 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0144 | 0.0136 |
Mycobacterium tuberculosis | Conserved protein | 0.0148 | 0.0687 | 0.1206 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0244 | 0.123 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0031 | 0.0022 | 0.0013 |
Loa Loa (eye worm) | RNA binding protein | 0.0473 | 0.2526 | 0.2519 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0191 | 0.0182 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0095 | 0.0382 | 0.2028 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0148 | 0.0687 | 0.1206 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0039 | 0.0066 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0066 | 0.0218 | 0.021 |
Loa Loa (eye worm) | DR-78 | 0.0031 | 0.0022 | 0.0012 |
Echinococcus granulosus | jumonji domain containing protein | 0.0086 | 0.0334 | 0.0326 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0032 | 0.0027 | 0.0019 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0066 | 0.0218 | 0.022 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0077 | 0.0284 | 0.0276 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0046 | 0.0106 | 0.0356 |
Echinococcus multilocularis | GPCR, family 2 | 0.0068 | 0.0231 | 0.0223 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0142 | 0.0132 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0031 | 0.0022 | 0.0013 |
Toxoplasma gondii | hypothetical protein | 0.0053 | 0.0144 | 0.0871 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0081 | 0.0305 | 0.2312 |
Entamoeba histolytica | Ran family GTPase | 0.007 | 0.024 | 0.4341 |
Onchocerca volvulus | 0.0163 | 0.0772 | 0.3053 | |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0066 | 0.0218 | 0.022 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0163 | 0.0772 | 0.581 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0066 | 0.0264 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0081 | 0.0305 | 0.4037 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0052 | 0.0045 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0047 | 0.0037 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0031 | 0.0022 | 0.0013 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0173 | 0.0829 | 0.1482 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0084 | 0.032 | 0.0327 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0022 | 0.0012 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.081 | 0.4438 | 0.4434 |
Echinococcus granulosus | importin subunit beta 1 | 0.0095 | 0.0382 | 0.0374 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0031 | 0.0022 | 0.0012 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0106 | 0.0356 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0084 | 0.032 | 0.0327 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0049 | 0.0125 | 0.0115 |
Leishmania major | hypothetical protein, conserved | 0.0049 | 0.0125 | 0.047 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0163 | 0.0772 | 0.6066 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0055 | 0.0158 | 0.1346 |
Onchocerca volvulus | 0.0148 | 0.0687 | 0.2708 | |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0095 | 0.0382 | 0.3004 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0106 | 0.0447 | 0.3587 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0066 | 0.0111 |
Mycobacterium leprae | Probable lipase LipE | 0.0148 | 0.0687 | 0.5034 |
Brugia malayi | Probable ClpP-like protease | 0.016 | 0.0752 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0687 | 0.0678 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0148 | 0.0687 | 0.388 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.0297 | 0.0287 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0148 | 0.0687 | 0.2772 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0077 | 0.0284 | 0.0276 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0062 | 0.0197 | 0.1344 |
Schistosoma mansoni | cpg binding protein | 0.0129 | 0.0576 | 0.0595 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.007 | 0.024 | 0.1733 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.004 | 0.0074 | 0.0593 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.0197 | 0.0198 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0075 | 0.0271 | 0.0263 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0068 | 0.0231 | 0.0223 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0035 | 0.0043 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0231 | 0.0234 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0068 | 0.0231 | 0.0222 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0148 | 0.0687 | 0.388 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0062 | 0.0197 | 0.0198 |
Brugia malayi | nuclear receptor NHR-88 | 0.0066 | 0.0218 | 0.0209 |
Onchocerca volvulus | 0.0464 | 0.2479 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.005 | 0.004 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 0.0744 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0085 | 0.008 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0062 | 0.0197 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0066 | 0.0218 | 0.021 |
Schistosoma mansoni | jumonji domain containing protein | 0.0161 | 0.0759 | 0.0788 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0294 | 0.1515 | 0.6079 |
Brugia malayi | beta-lactamase family protein | 0.0148 | 0.0687 | 0.0678 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0173 | 0.0829 | 0.1482 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0173 | 0.0829 | 0.656 |
Schistosoma mansoni | ran | 0.007 | 0.024 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0679 | 0.067 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0043 | 0.0033 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0068 | 0.0231 | 0.0222 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0148 | 0.0687 | 0.0678 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0114 | 0.0492 | 0.0484 |
Schistosoma mansoni | hypothetical protein | 0.0289 | 0.1484 | 0.1548 |
Echinococcus multilocularis | muscleblind protein | 0.1791 | 1 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.0627 | 0.0649 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0047 | 0.0191 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0191 | 0.1287 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0066 | 0.0218 | 0.021 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0056 | 0.0047 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0173 | 0.0829 | 0.1482 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0066 | 0.0218 | 0.0209 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.005 | 0.0131 | 0.0558 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0148 | 0.0687 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0365 | 0.0355 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0041 | 0.0078 | 0.0073 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0039 | 0.0066 | 0.0056 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0047 | 0.0191 |
Brugia malayi | RNA binding protein | 0.0473 | 0.2526 | 0.2519 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0041 | 0.0078 | 0.0068 |
Schistosoma mansoni | nuclear receptor | 0.0031 | 0.0022 | 0.0014 |
Loa Loa (eye worm) | TAR-binding protein | 0.0473 | 0.2526 | 0.2519 |
Plasmodium falciparum | importin beta, putative | 0.0095 | 0.0382 | 0.5065 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0231 | 0.0234 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0066 | 0.0218 | 0.021 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0326 | 0.1696 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.2526 | 0.2641 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0081 | 0.0305 | 0.1561 |
Onchocerca volvulus | 0.0061 | 0.0191 | 0.0688 | |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.0213 | 0.0205 |
Brugia malayi | nuclear receptor RXR | 0.0031 | 0.0022 | 0.0012 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0047 | 0.0191 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0173 | 0.0829 | 0.6337 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0066 | 0.0218 | 0.022 |
Loa Loa (eye worm) | fatty acid synthase | 0.0161 | 0.076 | 0.0751 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.007 | 0.024 | 0.117 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0148 | 0.0687 | 0.1206 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0141 | 0.0643 | 0.0635 |
Brugia malayi | tailless protein | 0.0031 | 0.0022 | 0.0012 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0056 | 0.0163 | 0.0701 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.1009 | 0.5567 | 0.5563 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0163 | 0.0772 | 0.137 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0106 | 0.0356 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0173 | 0.0829 | 0.6337 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0032 | 0.0027 | 0.0019 |
Echinococcus multilocularis | snurportin 1 | 0.1009 | 0.5567 | 0.5563 |
Echinococcus granulosus | dnaJ subfamily B | 0.171 | 0.9541 | 0.9541 |
Schistosoma mansoni | importin beta-1 | 0.0095 | 0.0382 | 0.0391 |
Echinococcus multilocularis | cpg binding protein | 0.0129 | 0.0576 | 0.0568 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0066 | 0.0218 | 0.021 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0131 | 0.0591 | 0.4512 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.0403 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0043 | 0.0033 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0043 | 0.0035 |
Echinococcus multilocularis | tumor protein p63 | 0.0689 | 0.3751 | 0.3746 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0039 | 0.0066 | 0.0111 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0679 | 0.0703 |
Brugia malayi | nuclear hormone receptor | 0.0066 | 0.0218 | 0.0209 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0041 | 0.0078 | 0.0188 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0066 | 0.0218 | 0.0209 |
Toxoplasma gondii | hypothetical protein | 0.0055 | 0.0158 | 0.0993 |
Loa Loa (eye worm) | acyl carrier protein | 0.0075 | 0.0272 | 0.0262 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0068 | 0.0231 | 0.0223 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0492 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0148 | 0.0687 | 0.0678 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0148 | 0.0687 | 0.5337 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0085 | 0.0343 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.007 | 0.024 | 0.117 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0077 | 0.028 | 0.1131 |
Brugia malayi | follicle stimulating hormone receptor | 0.0225 | 0.1123 | 0.1114 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0041 | 0.0078 | 0.0068 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0326 | 0.1696 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0031 | 0.0022 | 0.0014 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 0.5892 |
Toxoplasma gondii | exonuclease III APE | 0.0039 | 0.0066 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0772 | 0.0763 |
Echinococcus multilocularis | tar DNA binding protein | 0.0473 | 0.2526 | 0.252 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0066 | 0.0218 | 0.021 |
Loa Loa (eye worm) | histone methyltransferase | 0.0039 | 0.0069 | 0.0059 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0041 | 0.0078 | 0.007 |
Echinococcus granulosus | muscleblind protein | 0.1791 | 1 | 1 |
Echinococcus granulosus | snurportin 1 | 0.1009 | 0.5567 | 0.5563 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0125 | 0.0503 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0172 | 0.082 | 0.1465 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0097 | 0.0395 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0284 | 0.0275 |
Schistosoma mansoni | thyroid hormone receptor | 0.0066 | 0.0218 | 0.022 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0105 | 0.044 | 0.277 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0066 | 0.0218 | 0.021 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0085 | 0.0075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0066 | 0.0218 | 0.0209 |
Schistosoma mansoni | nuclear receptor | 0.0031 | 0.0022 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | nuclear receptor NHR-67 | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0041 | 0.0078 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0687 | 0.0678 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0046 | 0.0106 | 0.0356 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0043 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0448 | 0.0438 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0066 | 0.006 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0163 | 0.0772 | 0.6066 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.0752 | 0.0742 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0231 | 0.0234 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0066 | 0.0218 | 0.022 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0148 | 0.0687 | 0.0679 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0492 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1791 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0139 | 0.0129 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0174 | 0.0835 | 0.7075 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0066 | 0.0847 |
Mycobacterium ulcerans | thioesterase | 0.0136 | 0.0618 | 0.4741 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0154 | 0.0722 | 0.4089 |
Onchocerca volvulus | 0.0148 | 0.0687 | 0.2708 | |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0047 | 0.0191 |
Mycobacterium tuberculosis | Conserved protein | 0.0148 | 0.0687 | 0.1206 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0687 | 0.0678 |
Giardia lamblia | PHD finger protein 15 | 0.0062 | 0.0197 | 0.7519 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0035 | 0.0043 | 0.0034 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0203 | 0.0996 | 0.0988 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0066 | 0.006 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0246 | 0.1238 | 0.123 |
Echinococcus granulosus | FTZ F1 alpha | 0.0066 | 0.0218 | 0.021 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0047 | 0.0041 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.016 | 0.0752 | 0.0779 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0163 | 0.0772 | 0.6066 |
Brugia malayi | TAR-binding protein | 0.0473 | 0.2526 | 0.2519 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0144 | 0.0142 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0068 | 0.0231 | 0.0223 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.007 | 0.024 | 0.3177 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0066 | 0.0264 |
Mycobacterium ulcerans | lipase LipD | 0.0148 | 0.0687 | 0.5337 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.016 | 0.0754 | 0.0745 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0066 | 0.0218 | 0.021 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0136 | 0.0618 | 0.4398 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0047 | 0.0037 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0136 | 0.0618 | 0.1071 |
Brugia malayi | nuclear receptor RXR | 0.0035 | 0.0043 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0066 | 0.0218 | 0.0209 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0108 | 0.0458 | 0.2941 |
Schistosoma mansoni | coup transcription factor | 0.0066 | 0.0218 | 0.022 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0022 | 0.0013 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.2526 | 0.2641 |
Schistosoma mansoni | ran | 0.007 | 0.024 | 0.0243 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0148 | 0.0687 | 0.1206 |
Schistosoma mansoni | thyroid hormone receptor | 0.0066 | 0.0218 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium ulcerans | beta-lactamase | 0.0148 | 0.0687 | 0.5337 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0031 | 0.0022 | 0.0013 |
Onchocerca volvulus | 0.0148 | 0.0687 | 0.2708 | |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0036 | 0.005 | 0.0042 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0105 | 0.044 | 0.0431 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0077 | 0.0284 | 0.0289 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0144 | 0.0136 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0117 | 0.0511 | 0.0864 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0066 | 0.0218 | 0.0801 |
Schistosoma mansoni | hypothetical protein | 0.0854 | 0.4687 | 0.4908 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0134 | 0.0603 | 0.1043 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0163 | 0.0772 | 0.137 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0154 | 0.0722 | 0.4089 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0148 | 0.0687 | 0.1206 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0031 | 0.0022 | 0.0012 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0047 | 0.0039 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0244 | 0.123 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0128 | 0.0571 | 0.0561 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0473 | 0.2526 | 0.2519 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.01 | 0.0412 | 0.0423 |
Onchocerca volvulus | 0.0291 | 0.1497 | 0.6006 | |
Leishmania major | GTP-binding protein, putative | 0.007 | 0.024 | 0.117 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0108 | 0.0458 | 0.3372 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0108 | 0.0098 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0244 | 0.123 | 0.2259 |
Brugia malayi | hypothetical protein | 0.0163 | 0.0772 | 0.0763 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0085 | 0.0077 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0141 | 0.0643 | 0.0635 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.012 | 0.0526 | 0.0517 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0108 | 0.01 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.0627 | 0.0649 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0054 | 0.0153 | 0.0145 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0062 | 0.0197 | 0.0189 |
Giardia lamblia | Methyltransferase like 2 | 0.0049 | 0.0125 | 0.3392 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0022 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Brugia malayi | steroid hormone receptor | 0.0066 | 0.0218 | 0.0209 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0148 | 0.0687 | 0.2772 |
Onchocerca volvulus | 0.012 | 0.0526 | 0.2055 | |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0492 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0031 | 0.0022 | 0.0013 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0081 | 0.0305 | 0.1561 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0305 | 0.0295 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.2526 | 0.2641 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0148 | 0.0687 | 0.1206 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0084 | 0.0319 | 0.2444 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.007 | 0.024 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0084 | 0.032 | 0.0311 |
Schistosoma mansoni | nuclear hormone receptor | 0.0066 | 0.0218 | 0.022 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0068 | 0.0231 | 0.0223 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0232 | 0.1161 | 1 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0095 | 0.0382 | 0.0374 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0022 | 0.0014 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0218 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0687 | 0.0678 |
Trichomonas vaginalis | esterase, putative | 0.0148 | 0.0687 | 0.2772 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0085 | 0.0075 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0031 | 0.0022 | 0.0013 |
Brugia malayi | PHD-finger family protein | 0.0062 | 0.0197 | 0.0187 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0108 | 0.01 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0052 | 0.0142 | 0.014 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0105 | 0.044 | 0.0725 |
Schistosoma mansoni | zinc finger protein | 0.0031 | 0.0022 | 0.0014 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0066 | 0.0218 | 0.0209 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0305 | 0.0295 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.005 | 0.0131 | 0.0126 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0163 | 0.0772 | 0.0763 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0062 | 0.0197 | 0.1344 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0066 | 0.0218 | 0.021 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 0.0744 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0101 | 0.0417 | 0.0429 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0066 | 0.0218 | 0.021 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0148 | 0.0687 | 0.5337 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0163 | 0.0772 | 0.581 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0154 | 0.0722 | 0.4089 |
Brugia malayi | beta-lactamase family protein | 0.0148 | 0.0687 | 0.0678 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0055 | 0.0158 | 0.2079 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0148 | 0.0687 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0191 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0403 | 0.0394 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0035 | 0.0043 | 0.0033 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0036 | 0.0052 | 0.0043 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0047 | 0.0191 |
Loa Loa (eye worm) | beta-lactamase | 0.0148 | 0.0687 | 0.0678 |
Echinococcus granulosus | tumor protein p63 | 0.0689 | 0.3751 | 0.3746 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0203 | 0.0996 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0032 | 0.0022 |
Plasmodium falciparum | phd finger protein, putative | 0.0062 | 0.0197 | 0.2599 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0105 | 0.044 | 0.0725 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.016 | 0.0752 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0246 | 0.1238 | 0.1231 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0081 | 0.0305 | 0.4037 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0326 | 0.1696 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0246 | 0.1238 | 0.129 |
Brugia malayi | beta-lactamase | 0.0148 | 0.0687 | 0.0678 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0061 | 0.0191 | 0.0181 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0108 | 0.0104 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0066 | 0.0218 | 0.0801 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0031 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0022 | 0.0012 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 20 uM | Antiproliferative activity against human MDA-MB-231 cells after 24 hrs by MTT assay | ChEMBL. | 24189055 |
IC50 (functional) | > 50 uM | Cytotoxicity against human MCF7 cells after 18 hrs by MTT assay | ChEMBL. | 19932024 |
IC50 (functional) | > 50 uM | Cytotoxicity against human MDA-MB-231 cells after 18 hrs by MTT assay | ChEMBL. | 19932024 |
IC50 (functional) | > 50 uM | Cytotoxicity against human Ishikawa cells after 18 hrs by MTT assay | ChEMBL. | 19932024 |
IC50 (functional) | > 50 uM | Cytotoxicity against human DU145 cells after 18 hrs by MTT assay | ChEMBL. | 19932024 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.