Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | choline o-acyltransferase | 0.0039 | 0.0675 | 0.0561 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0033 | 0.0502 | 0.0502 |
Treponema pallidum | NADH oxidase | 0.0033 | 0.0502 | 0.5 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0033 | 0.0502 | 0.146 |
Echinococcus granulosus | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Plasmodium falciparum | thioredoxin reductase | 0.0033 | 0.0502 | 0.146 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0215 | 0.5502 | 0.6354 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0208 | 0.0208 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0271 | 0.0418 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0039 | 0.0675 | 0.0675 |
Onchocerca volvulus | 0.0039 | 0.0675 | 0.2873 | |
Plasmodium falciparum | glutathione reductase | 0.0096 | 0.2219 | 1 |
Giardia lamblia | Pyruvate kinase | 0.0068 | 0.147 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0355 | 0.0355 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0068 | 0.147 | 1 |
Leishmania major | pyruvate kinase | 0.0068 | 0.147 | 0.2384 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0039 | 0.0675 | 0.0561 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0039 | 0.0675 | 0.0882 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0024 | 0.026 | 0.026 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.2054 | 0.2215 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0429 | 0.1101 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0033 | 0.0502 | 0.146 |
Schistosoma mansoni | lamin | 0.0028 | 0.0355 | 0.0176 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0096 | 0.2219 | 0.3798 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.171 | 0.2838 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0271 | 0.0418 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0068 | 0.147 | 0.2384 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0068 | 0.147 | 0.6277 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0033 | 0.0502 | 0.0555 |
Echinococcus granulosus | snurportin 1 | 0.0325 | 0.854 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.025 | 0.6465 | 0.751 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0457 | 0.0299 |
Leishmania major | pyruvate kinase | 0.0068 | 0.147 | 0.2384 |
Onchocerca volvulus | 0.0039 | 0.0675 | 0.2873 | |
Loa Loa (eye worm) | inositol-1 | 0.0077 | 0.171 | 0.171 |
Echinococcus granulosus | choline O acetyltransferase | 0.0039 | 0.0675 | 0.0561 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0457 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0341 | 0.0341 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0457 | 0.0299 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0039 | 0.0675 | 0.0561 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2629 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0218 | 0.5585 | 0.8837 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.2054 | 0.2215 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0035 | 0.0555 | 0.1728 |
Toxoplasma gondii | thioredoxin reductase | 0.0096 | 0.2219 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.2054 | 0.2215 |
Echinococcus granulosus | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0457 | 0.0299 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0039 | 0.0675 | 0.2323 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0039 | 0.0675 | 0.2323 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3089 | 0.3458 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0457 | 0.0457 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0039 | 0.0675 | 0.2323 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0429 | 0.1101 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0068 | 0.147 | 0.2384 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0068 | 0.147 | 0.147 |
Onchocerca volvulus | 0.0039 | 0.0675 | 0.2873 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3089 | 0.3458 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0096 | 0.2219 | 0.2219 |
Echinococcus multilocularis | tar DNA binding protein | 0.0127 | 0.3089 | 0.3458 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0271 | 0.0418 |
Brugia malayi | Thioredoxin reductase | 0.0096 | 0.2219 | 0.2219 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.2327 | 0.2327 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0039 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | pyruvate kinase | 0.0068 | 0.147 | 0.147 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0033 | 0.0502 | 0.146 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0039 | 0.0675 | 0.0882 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0035 | 0.0555 | 0.1728 |
Plasmodium vivax | pyruvate kinase, putative | 0.0068 | 0.147 | 0.6277 |
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0429 | 0.0266 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0077 | 0.171 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0457 | 0.0299 |
Plasmodium falciparum | thioredoxin reductase | 0.0096 | 0.2219 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0096 | 0.2219 | 0.2219 |
Echinococcus multilocularis | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Plasmodium falciparum | pyruvate kinase | 0.0068 | 0.147 | 0.6277 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.2054 | 0.2054 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0033 | 0.0502 | 0.146 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 1 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0054 | 0.1074 | 0.104 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0429 | 0.0266 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2629 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0127 | 0.3089 | 0.3089 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0039 | 0.0675 | 0.0882 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0127 | 0.3089 | 0.3089 |
Chlamydia trachomatis | pyruvate kinase | 0.0068 | 0.147 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.171 | 0.2838 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0502 | 0.146 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0355 | 0.0176 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0033 | 0.0502 | 0.146 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0069 | 0.1488 | 0.0038 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.2327 | 0.2327 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0033 | 0.0502 | 0.0555 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0033 | 0.0502 | 0.146 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0039 | 0.0675 | 0.0675 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0033 | 0.0502 | 0.0352 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0033 | 0.0502 | 0.0555 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0039 | 0.0675 | 0.0675 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0068 | 0.147 | 0.147 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0675 | 0.0882 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2629 | 1 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0355 | 0.0176 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0457 | 0.0299 |
Loa Loa (eye worm) | RNA binding protein | 0.0127 | 0.3089 | 0.3089 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0457 | 0.0299 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0039 | 0.0675 | 0.0882 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0039 | 0.0675 | 0.0882 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0215 | 0.5502 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0096 | 0.2219 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.2327 | 0.2327 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0457 | 0.0457 |
Schistosoma mansoni | inositol monophosphatase | 0.0077 | 0.171 | 0.1803 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0215 | 0.5502 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0218 | 0.5585 | 0.8602 |
Plasmodium falciparum | glutathione reductase | 0.0033 | 0.0502 | 0.146 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0429 | 0.1101 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0993 | 0.0942 |
Echinococcus multilocularis | pyruvate kinase | 0.0068 | 0.147 | 0.1515 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0033 | 0.0502 | 0.0352 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0077 | 0.171 | 1 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0068 | 0.147 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0096 | 0.2219 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0457 | 0.0299 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0271 | 0.0119 |
Echinococcus granulosus | tar DNA binding protein | 0.0127 | 0.3089 | 0.3458 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0993 | 0.0942 |
Schistosoma mansoni | pyruvate kinase | 0.0068 | 0.147 | 0.1515 |
Brugia malayi | hypothetical protein | 0.011 | 0.2629 | 0.2629 |
Echinococcus multilocularis | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0033 | 0.0502 | 0.146 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0457 | 0.0299 |
Schistosoma mansoni | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0069 | 0.1488 | 0.1715 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0096 | 0.2219 | 0.2413 |
Echinococcus granulosus | pyruvate kinase | 0.0068 | 0.147 | 0.1515 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0457 | 0.0457 |
Leishmania major | trypanothione reductase | 0.0096 | 0.2219 | 0.3798 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0127 | 0.3089 | 0.3089 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0215 | 0.5502 | 1 |
Onchocerca volvulus | 0.0051 | 0.0993 | 0.5725 | |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0039 | 0.0675 | 0.0675 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0077 | 0.171 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1462 | 0.1505 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0355 | 0.0355 |
Onchocerca volvulus | 0.0039 | 0.0675 | 0.2873 | |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0429 | 0.0266 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0355 | 0.0355 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.0021 | 0.016 | 0.016 |
Brugia malayi | MH2 domain containing protein | 0.0115 | 0.2764 | 0.2764 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0215 | 0.5502 | 0.6354 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0355 | 0.0355 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0077 | 0.171 | 0.6206 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.171 | 0.7472 |
Schistosoma mansoni | pyruvate kinase | 0.0068 | 0.147 | 0.1515 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0355 | 0.0355 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.2054 | 0.2215 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0242 | 0.6254 | 1 |
Giardia lamblia | Pyruvate kinase | 0.0035 | 0.0555 | 0.2754 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0675 | 0.2323 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0271 | 0.0119 |
Echinococcus granulosus | pyruvate kinase | 0.0068 | 0.147 | 0.1515 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.2054 | 0.2215 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0429 | 0.1101 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0035 | 0.0555 | 0.1728 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0993 | 0.0993 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0218 | 0.5585 | 0.8837 |
Schistosoma mansoni | lamin | 0.0028 | 0.0355 | 0.0176 |
Brugia malayi | hypothetical protein | 0.025 | 0.6465 | 0.6465 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.025 | 0.6465 | 0.751 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0033 | 0.0502 | 0.0352 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.2054 | 0.2215 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.2629 | 0.2906 |
Schistosoma mansoni | choline o-acyltransferase | 0.0039 | 0.0675 | 0.0561 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0039 | 0.0675 | 0.0561 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0355 | 0.0176 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0033 | 0.0502 | 0.1954 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0502 | 0.146 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0242 | 0.6254 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0033 | 0.0502 | 0.2327 |
Brugia malayi | RNA binding protein | 0.0127 | 0.3089 | 0.3089 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.1462 | 0.1462 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.2629 | 0.2906 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0429 | 0.0429 |
Schistosoma mansoni | inositol monophosphatase | 0.0077 | 0.171 | 0.1803 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.2054 | 0.2054 |
Trypanosoma brucei | trypanothione reductase | 0.0096 | 0.2219 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0429 | 0.0429 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0115 | 0.2764 | 0.2764 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0096 | 0.2219 | 0.2985 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0068 | 0.147 | 0.1684 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0218 | 0.5585 | 0.8837 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0242 | 0.6254 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0218 | 0.5585 | 0.8837 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0242 | 0.6254 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0325 | 0.854 | 0.854 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3089 | 0.3458 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0077 | 0.171 | 0.7472 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.171 | 0.2838 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0429 | 0.1101 |
Schistosoma mansoni | hypothetical protein | 0.0325 | 0.854 | 1 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0068 | 0.147 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.2327 | 0.2327 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0115 | 0.2764 | 0.2764 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0457 | 0.0299 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0039 | 0.0675 | 0.0882 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0068 | 0.147 | 0.6277 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0068 | 0.147 | 0.84 |
Brugia malayi | Inositol-1 | 0.0077 | 0.171 | 0.171 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.147 | 0.147 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0077 | 0.171 | 0.1803 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0355 | 0.0176 |
Mycobacterium tuberculosis | Probable reductase | 0.0218 | 0.5585 | 0.8837 |
Brugia malayi | Choline O-acetyltransferase | 0.0039 | 0.0675 | 0.0675 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0024 | 0.026 | 0.026 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0218 | 0.5585 | 0.8837 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0077 | 0.171 | 0.1803 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0271 | 0.0259 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0048 | 0.0902 | 0.2865 |
Loa Loa (eye worm) | pyruvate kinase | 0.0068 | 0.147 | 0.147 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0675 | 0.0882 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0902 | 0.0902 |
Echinococcus granulosus | lamin | 0.0028 | 0.0355 | 0.0176 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0077 | 0.171 | 1 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.2629 | 0.2906 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0457 | 0.0457 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0355 | 0.0176 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0675 | 0.0882 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0033 | 0.0502 | 0.146 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3089 | 0.3458 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0039 | 0.0675 | 0.2323 |
Mycobacterium ulcerans | pyruvate kinase | 0.0068 | 0.147 | 0.8012 |
Loa Loa (eye worm) | hypothetical protein | 0.025 | 0.6465 | 0.6465 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0675 | 0.0882 |
Brugia malayi | glutathione reductase | 0.0096 | 0.2219 | 0.2219 |
Brugia malayi | TAR-binding protein | 0.0127 | 0.3089 | 0.3089 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0675 | 0.0675 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0502 | 0.0555 |
Brugia malayi | Choline O-acetyltransferase | 0.0039 | 0.0675 | 0.0675 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0068 | 0.147 | 0.6277 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.3089 | 0.3458 |
Echinococcus multilocularis | pyruvate kinase | 0.0068 | 0.147 | 0.1515 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0355 | 0.0176 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0675 | 0.0882 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0048 | 0.0902 | 0.0902 |
Brugia malayi | RNA, U transporter 1 | 0.0087 | 0.1975 | 0.1975 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0039 | 0.0675 | 0.0882 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.2054 | 0.2215 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0068 | 0.147 | 0.84 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0208 | 0.0208 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.2629 | 0.2906 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0077 | 0.171 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0096 | 0.2219 | 0.2413 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1462 | 0.1462 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0039 | 0.0675 | 0.0882 |
Echinococcus multilocularis | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Echinococcus multilocularis | snurportin 1 | 0.0325 | 0.854 | 1 |
Echinococcus granulosus | pyruvate kinase | 0.0035 | 0.0555 | 0.0417 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2629 | 1 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0033 | 0.0502 | 0.1954 |
Loa Loa (eye worm) | pyruvate kinase | 0.0068 | 0.147 | 0.147 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 45 uM | Inhibition of MAOA in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorimetry | ChEMBL. | 20117937 |
IC50 (binding) | > 100 uM | Inhibition of MAOB in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorimetry | ChEMBL. | 20117937 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.