Detailed information for compound 109188

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 347.432 | Formula: C17H21N3O3S
  • H donors: 1 H acceptors: 2 LogP: 2.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1=C(OCN1C)NS(=O)(=O)c1cccc2c1cccc2N(C)C
  • InChi: 1S/C17H21N3O3S/c1-12-17(23-11-20(12)4)18-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)19(2)3/h5-10,18H,11H2,1-4H3
  • InChiKey: WYKROYHYGMHFRJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus geminin 0.0166 0.6977 1
Toxoplasma gondii thioredoxin reductase 0.0046 0.1792 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0206 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.177 0.4157
Echinococcus granulosus tar DNA binding protein 0.0062 0.2474 0.3423
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.3795 0.4084
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0481 0.0178
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0825 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0456 0.0475
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.4852 0.4784
Schistosoma mansoni hypothetical protein 0.0031 0.1124 0.1451
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0855 0.0619
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.1727 0.2331
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.4363 0.8844
Schistosoma mansoni hypothetical protein 0.0011 0.0265 0.0197
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0855 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0206 0.0076
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0206 0.011
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2474 0.3423
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0481 0.1733
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.4363 0.8844
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.4017 0.3938
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Brugia malayi glutathione reductase 0.0046 0.1792 0.1684
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.1313 0.1726
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0206 0.0076
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.4874 1
Mycobacterium ulcerans hypothetical protein 0.0024 0.0825 1
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.4852 0.4784
Plasmodium falciparum thioredoxin reductase 0.0016 0.0481 0.1733
Entamoeba histolytica hypothetical protein 0.0035 0.1313 0.3459
Entamoeba histolytica recQ family helicase, putative 0.0013 0.033 0.0869
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0825 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0456 0.033
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0481 0.1733
Loa Loa (eye worm) glutathione reductase 0.0046 0.1792 0.1684
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.3795 0.5351
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0481 0.0178
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0296 0.0168
Loa Loa (eye worm) hypothetical protein 0.0067 0.2678 0.2581
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.1727 0.1617
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0265 0.0197
Loa Loa (eye worm) pax transcription factor protein 2 0.0236 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0206 0.115
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2474 0.3423
Echinococcus multilocularis geminin 0.0166 0.6977 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.4363 0.8844
Echinococcus multilocularis tar DNA binding protein 0.0062 0.2474 0.3423
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0481 0.2684
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2474 0.3423
Brugia malayi RNA binding protein 0.0062 0.2474 0.2374
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0456 0.0149
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.1727 0.2331
Brugia malayi Latrophilin receptor protein 2 0.0031 0.1124 0.1007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0481 0.0178
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.3795 0.4084
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.1313 0.1726
Plasmodium falciparum thioredoxin reductase 0.0046 0.1792 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0804 0.137
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.3795 0.5351
Echinococcus granulosus bloom syndrome protein 0.0024 0.0804 0.0984
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0481 0.0186
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.1727 0.2331
Loa Loa (eye worm) RNA binding protein 0.0062 0.2474 0.2374
Schistosoma mansoni hypothetical protein 0.0031 0.1124 0.1451
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0481 0.0178
Schistosoma mansoni hypothetical protein 0.0031 0.1124 0.1451
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0206 0.115
Leishmania major trypanothione reductase 0.0046 0.1792 0.1724
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.059 0.0671
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0804 0.0984
Echinococcus granulosus GPCR family 2 0.0031 0.1124 0.1451
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0206 0.011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0466 0.2602
Leishmania major hypothetical protein, conserved 0.0025 0.0855 0.0619
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0456 0.0475
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0681 0.2991
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0481 0.0766
Schistosoma mansoni hypothetical protein 0.0067 0.2678 0.3721
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0456 0.0475
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0481 0.0178
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0481 0.0512
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0804 0.0683
Schistosoma mansoni hypothetical protein 0.0166 0.6977 1
Brugia malayi hypothetical protein 0.0035 0.1313 0.1197
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.1727 0.1617
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.8814 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0206 0.0076
Schistosoma mansoni hypothetical protein 0.0166 0.6977 1
Brugia malayi Thioredoxin reductase 0.0046 0.1792 0.1684
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.1313 0.1726
Plasmodium vivax glutathione reductase, putative 0.0046 0.1792 1
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.1792 0.3025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.1727 0.2331
Entamoeba histolytica hypothetical protein 0.0035 0.1313 0.3459
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.8814 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0481 0.0186
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0825 0.1014
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.1792 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0481 0.5
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0481 0.0056
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.1792 0.2427
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0481 0.0178
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.2474 0.2374
Schistosoma mansoni hypothetical protein 0.0035 0.1313 0.1726
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.1124 0.1451
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0481 0.5
Plasmodium falciparum glutathione reductase 0.0016 0.0481 0.1733
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.4874 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0481 0.0512
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0481 0.0512
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.3795 0.3712
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0456 0.0475
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0855 0.4093
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0825 0.0836
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0804 0.137
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.3795 0.3655
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.1727 0.2331
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.2474 0.2374
Plasmodium falciparum glutathione reductase 0.0046 0.1792 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2474 0.3423
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0825 0.0584
Schistosoma mansoni DNA helicase recq1 0.001 0.0206 0.011
Trypanosoma brucei trypanothione reductase 0.0046 0.1792 0.1724
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0296 0.0168
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0206 0.011
Echinococcus multilocularis GPCR, family 2 0.0031 0.1124 0.1451
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0456 0.0475
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0825 0.143
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0481 0.0436
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.3795 0.4084
Giardia lamblia Kinase, PLK 0.0092 0.3795 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.4874 1
Brugia malayi MH2 domain containing protein 0.0117 0.4852 0.4784
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.3795 0.5351
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.8814 1
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0456 0.0149
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0456 0.0149
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0481 0.0178
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Schistosoma mansoni hypothetical protein 0.0031 0.1124 0.1451
Entamoeba histolytica hypothetical protein 0.0035 0.1313 0.3459
Entamoeba histolytica hypothetical protein 0.0035 0.1313 0.3459
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0456 0.0149
Brugia malayi TAR-binding protein 0.0062 0.2474 0.2374
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2474 0.3423
Schistosoma mansoni DNA helicase recq5 0.001 0.0206 0.011
Brugia malayi isocitrate dehydrogenase 0.0015 0.0456 0.033
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0825 1
Leishmania major hypothetical protein, conserved 0.0208 0.8814 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.1727 0.2331
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.1792 0.1684
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0456 0.2545
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.4874 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0481 0.5
Loa Loa (eye worm) hypothetical protein 0.0118 0.4914 0.4847
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.4017 0.3938
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0456 0.0475
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.1792 0.1724
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0481 0.0355
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.1124 0.1451
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0456 0.1576
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.4017 0.3938
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.4363 0.8844
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0481 0.0178
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.3795 0.3712
Mycobacterium tuberculosis Probable reductase 0.0106 0.4363 0.8844
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0855 0.4772
Onchocerca volvulus 0.0236 1 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0456 0.0149
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0855 0.4093
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.1124 0.1451
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0825 0.1014
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0855 0.0619
Mycobacterium tuberculosis Conserved protein 0.0024 0.0825 0.0836
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0456 0.2545
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.1124 0.1007
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.2678 0.2581
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0206 0.0076
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0456 0.0475
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.4363 0.8844
Trypanosoma brucei polo-like protein kinase 0.0092 0.3795 0.4084
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0475 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3795 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0481 0.0178
Loa Loa (eye worm) RecQ helicase 0.0024 0.0804 0.0683
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.1124 0.1451
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0855 0.2988
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.1792 0.2427
Loa Loa (eye worm) TAR-binding protein 0.0062 0.2474 0.2374
Schistosoma mansoni kinase 0.0047 0.1823 0.2472
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0265 0.0197
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0825 0.0584
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0825 0.0584
Mycobacterium ulcerans hypothetical protein 0.0024 0.0825 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0481 0.0178
Brugia malayi hypothetical protein 0.0016 0.0476 0.035
Brugia malayi hypothetical protein 0.0025 0.0855 0.0734
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0456 0.033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.1124 0.1007
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0481 0.2684
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.3795 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0855 0.0734
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0481 0.0436
Loa Loa (eye worm) hypothetical protein 0.0098 0.4017 0.3938
Treponema pallidum NADH oxidase 0.0016 0.0481 0.5
Loa Loa (eye worm) hypothetical protein 0.0031 0.1124 0.1007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.1727 0.2331
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.177 0.4157

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) > 100 mg kg-1 Ability to protect rats from ET-1 induced sudden death in rats after peroral administration ChEMBL. 8667356
Lethality (functional) 0 In vivo prevention of ET-1-induced sudden death in rats by pretreatment with endothelin receptor antagonist at a dose of 10 mg/kg p.o.; nd = not determined ChEMBL. 8667356
Lethality (functional) 0 In vivo prevention of ET-1-induced sudden death in rats by pretreatment with endothelin receptor antagonist at a dose of 30 mg/kg p.o.; nd = not determined ChEMBL. 8667356
Lethality (functional) = 6 In vivo prevention of ET-1-induced sudden death in 6 rats by pretreatment with endothelin receptor antagonist at a dose of 30 mg/kg p.o. ChEMBL. 8667356
pA2 (functional) = 7.09 Functional vascular ET-1 antagonism was determined in rabbit aorta rings with intact endothelium ChEMBL. 8667356

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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