Detailed information for compound 1093531

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 490.427 | Formula: C26H14N6O5
  • H donors: 0 H acceptors: 6 LogP: 4.25 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc(cc1)c1cc(nc2c1c1nc3ccccc3c(=O)n1cn2)c1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C26H14N6O5/c33-26-19-3-1-2-4-21(19)29-25-23-20(15-5-9-17(10-6-15)31(34)35)13-22(28-24(23)27-14-30(25)26)16-7-11-18(12-8-16)32(36)37/h1-14H
  • InChiKey: WJCRFEZVOXZJOO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0299 0.0895
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0007 0.0029 0.0731
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0179 0.0275
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0015 0.0179 0.0318
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0111 0.0147
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0179 0.0275
Plasmodium vivax thioredoxin reductase, putative 0.0158 0.3046 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0107 0.0352
Loa Loa (eye worm) hypothetical protein 0.0018 0.0246 0.0438
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0299 0.0895
Entamoeba histolytica thioredoxin reductase, putative 0.0015 0.0179 0.4498
Echinococcus multilocularis bloom syndrome protein 0.0027 0.0419 0.0462
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0015 0.0179 0.0268
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0107 0.0352
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0075 0.0133
Echinococcus granulosus thioredoxin glutathione reductase 0.016 0.3088 0.3623
Loa Loa (eye worm) hypothetical protein 0.0018 0.0246 0.0438
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0086 0.1233
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.0107 0.0093
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0179 0.0177
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0055 0.0983 0.1129
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0055 0.0983 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0233 0.0233
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.0107 0.0093
Loa Loa (eye worm) hypothetical protein 0.0024 0.0367 0.0653
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0015 0.0179 0.0496
Schistosoma mansoni glutamate synthase 0.0015 0.0179 0.0179
Schistosoma mansoni hypothetical protein 0.0021 0.0305 0.0305
Schistosoma mansoni hypothetical protein 0.0015 0.0179 0.0179
Schistosoma mansoni glutaminase 0.0287 0.5625 0.5625
Brugia malayi steroid hormone receptor 0.001 0.0086 0.0102
Brugia malayi Bromodomain containing protein 0.0078 0.1438 0.2518
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0179 0.0587
Mycobacterium ulcerans NADH dehydrogenase 0.0015 0.0179 0.0268
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0367 0.0454
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0055 0.0983 1
Brugia malayi nuclear hormone receptor 0.001 0.0086 0.0102
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0086 0.0086
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3161
Brugia malayi PHD-finger family protein 0.0027 0.0426 0.071
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0107 0.014
Brugia malayi glutamate synthase 0.0015 0.0179 0.0268
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0227 0.0276
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0029 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0086 0.0067
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0367 0.9243
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.036 0.7091 0.8981
Loa Loa (eye worm) hypothetical protein 0.0071 0.1318 0.2342
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0246 0.0257
Loa Loa (eye worm) glutaminase 0.0287 0.5625 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.04 0.7895 1
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0245 0.0436
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0029 0.0025
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0367 0.1122
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0398 0.1222
Trichomonas vaginalis glutathione reductase, putative 0.0055 0.0983 0.171
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0179 0.0275
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0246 0.0388
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0367 0.0605
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0398 0.3316
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0015 0.0179 0.0215
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0086 0.0067
Mycobacterium ulcerans glutamate synthase subunit beta 0.0015 0.0179 0.0268
Schistosoma mansoni DNA helicase recq1 0.0011 0.0107 0.0107
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0246 0.072
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0055 0.0983 0.3161
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0029 0.0025
Mycobacterium ulcerans ferredoxin reductase 0.0015 0.0179 0.0268
Leishmania major hypothetical protein, conserved 0.0025 0.0381 0.1167
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0086 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0381 0.1167
Loa Loa (eye worm) hypothetical protein 0.0007 0.0029 0.0052
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0179 0.0268
Schistosoma mansoni cpg binding protein 0.003 0.0491 0.0491
Plasmodium vivax ferrodoxin reductase, putative 0.0015 0.0179 0.0496
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0172 0.0262
Loa Loa (eye worm) hypothetical protein 0.0045 0.0785 0.1395
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0179 0.0177
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0055 0.0983 0.3161
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0179 0.0587
Schistosoma mansoni DNA helicase recq5 0.0011 0.0107 0.0107
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0029 0.0095
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0172 0.0473
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0179 0.0215
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0086 0.0067
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0381 0.1167
Echinococcus multilocularis glutamate synthase 0.0015 0.0179 0.0177
Giardia lamblia NADH oxidase lateral transfer candidate 0.0055 0.0983 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0381 0.1252
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0107 0.014
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0086 0.0086
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0015 0.0179 0.4498
Brugia malayi Thioredoxin reductase 0.0158 0.3046 0.5391
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0381 0.1167
Schistosoma mansoni glutamate synthase 0.0015 0.0179 0.0179
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0015 0.0179 0.0215
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0179 0.4498
Trypanosoma cruzi trypanothione reductase, putative 0.0158 0.3046 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0299 0.752
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0367 0.0605
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0029 0.0095
Loa Loa (eye worm) programmed cell death 8 0.0015 0.0179 0.0318
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0015 0.0179 0.0215
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0055 0.0983 0.1704
Schistosoma mansoni thyroid hormone receptor 0.001 0.0086 0.0086
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.1078 0.3539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0086 0.0153
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0367 0.043
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0246 0.072
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0299 0.0482
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0179 0.0587
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0055 0.0983 0.3161
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.0107 0.0191
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0015 0.0179 0.0268
Brugia malayi glutaminase DH11.1 0.0287 0.5625 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0086 0.0102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0086 0.0102
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0025 0.00000000016123
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0086 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0025 0.00000000016123
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0086 0.0102
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0246 0.0257
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.004 0.0692 0.1185
Treponema pallidum oxidoreductase 0.0015 0.0179 0.182
Schistosoma mansoni hypothetical protein 0.0429 0.8472 0.8472
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3226
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0398 0.1222
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0246 0.03
Mycobacterium tuberculosis Putative ferredoxin reductase 0.036 0.7091 0.8981
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0398 0.1305
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0179 0.019
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0029 0.0095
Schistosoma mansoni hypothetical protein 0.0185 0.3588 0.3588
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0419 0.0703
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0179 0.0268
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0179 0.0268
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0038 0.0011
Loa Loa (eye worm) thioredoxin reductase 0.0158 0.3046 0.5415
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0179 0.0179
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0055 0.0983 0.3226
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0015 0.0179 0.0817
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0109 0.0095
Schistosoma mansoni hypothetical protein 0.0185 0.3588 0.3588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0086 0.0153
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0086 0.0067
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0172 0.432
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0227 0.0276
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0015 0.0179 0.0496
Trypanosoma brucei NADH dehydrogenase 0.0015 0.0179 0.0496
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0179 0.4498
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0367 0.0605
Schistosoma mansoni thyroid hormone receptor 0.001 0.0086 0.0086
Toxoplasma gondii selenide, water dikinase 0.0015 0.0179 0.0587
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0179 0.0275
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0086 0.0153
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0243 0.0797
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0025 0.00000000016123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0025 0.00000000016123
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0015 0.0179 0.0215
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.0107 0.026
Mycobacterium tuberculosis Probable dehydrogenase 0.036 0.7091 0.8981
Brugia malayi Bromodomain containing protein 0.0039 0.0662 0.1132
Leishmania major hypothetical protein, conserved 0.0015 0.0198 0.0558
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0367 0.0454
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0367 0.0605
Trypanosoma cruzi NADH dehydrogenase, putative 0.0015 0.0179 0.0587
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0299 0.0489
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0367 0.9243
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0029 0.0025
Onchocerca volvulus 0.001 0.0086 0.1233
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0179 0.0496
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0299 0.0982
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0015 0.0179 0.019
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0179 0.0177
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0086 0.0067
Giardia lamblia Thioredoxin reductase 0.0015 0.0179 0.0817
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0055 0.0983 0.3161
Echinococcus multilocularis cpg binding protein 0.0034 0.0564 0.0634
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0086 0.0086
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0086 0.0086
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.1167 0.1167
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0015 0.0179 0.0177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3226
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.1129 0.1303
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.036 0.7091 0.8978
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0015 0.0179 0.0268
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0086 0.0153
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0015 0.0179 0.0587
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0381 0.1252
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0038 0.0011
Leishmania major hypothetical protein, conserved 0.0015 0.0179 0.0496
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0055 0.0983 0.1704
Treponema pallidum NADH oxidase 0.0055 0.0983 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0086 0.0102
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0299 0.0367
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3226
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0367 0.0605
Entamoeba histolytica disulphide oxidoreductase, putative 0.0015 0.0179 0.4498
Brugia malayi CXXC zinc finger family protein 0.003 0.0491 0.0826
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0015 0.0179 0.0496
Loa Loa (eye worm) hypothetical protein 0.0025 0.0381 0.0678
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0491 0.0873
Echinococcus granulosus FTZ F1 alpha 0.001 0.0086 0.0067
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0233 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0086 0.0102
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0179 0.0587
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0086 0.0067
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0055 0.0983 0.3161
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0398 0.0707
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0086 0.0102
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0015 0.0179 0.0268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0086 0.0153
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0025 0.00000000016123
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0179 0.0587
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0075 0.0054
Loa Loa (eye worm) hypothetical protein 0.0039 0.0664 0.118
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0381 0.1252
Echinococcus granulosus cpg binding protein 0.0034 0.0564 0.0634
Plasmodium falciparum ferrodoxin reductase-like protein 0.0015 0.0179 0.0496
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0015 0.0179 0.0275
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0367 0.0605
Loa Loa (eye worm) hypothetical protein 0.0024 0.0367 0.0653
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0029 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0246 0.0246
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0055 0.0983 0.3161
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0367 0.9243
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0029 0.0007
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.036 0.7091 0.8981
Trypanosoma brucei trypanothione reductase 0.0158 0.3046 1
Brugia malayi nuclear receptor NHR-88 0.001 0.0086 0.0102
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0367 0.0605
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0015 0.0179 0.4498
Echinococcus granulosus geminin 0.0185 0.3588 0.4215
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0367 0.0605
Loa Loa (eye worm) hypothetical protein 0.0018 0.0246 0.0438
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.04 0.7895 1
Echinococcus granulosus glutamate synthase 0.0015 0.0179 0.0177
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0055 0.0983 0.3161
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0246 0.0246
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0055 0.0983 1
Mycobacterium tuberculosis Probable reductase 0.036 0.7091 0.8981
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0179 0.0496
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0086 0.0086
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0179 0.0177
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0299 0.0895
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0179 0.0587
Echinococcus multilocularis zinc finger protein 0.0022 0.0318 0.0343
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0299 0.0489
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0086 0.0102
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0299 0.032
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0299 0.0532
Toxoplasma gondii exonuclease III APE 0.0021 0.0299 0.0982
Brugia malayi ecdysteroid receptor 0.001 0.0086 0.0102
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0055 0.0983 0.3161
Schistosoma mansoni ap endonuclease 0.0021 0.0299 0.0299
Echinococcus granulosus flap endonuclease 1 0.0025 0.0398 0.0437
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0299 0.219
Echinococcus granulosus dnaJ subfamily B 0.0429 0.8472 1
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0015 0.0179 0.0496
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0086 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0025 0.00000000016123
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0614 0.0693
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0029 0.0025
Trichomonas vaginalis mercuric reductase, putative 0.0055 0.0983 0.171
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0179 0.0496
Loa Loa (eye worm) hypothetical protein 0.0011 0.0107 0.0191
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0015 0.0179 0.0587
Brugia malayi glutathione reductase 0.0158 0.3046 0.5391
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0398 0.0437
Loa Loa (eye worm) glutathione reductase 0.0158 0.3046 0.5415
Mycobacterium ulcerans hypothetical protein 0.0015 0.0179 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0086 0.0102
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0015 0.0179 0.0177
Brugia malayi Bloom's syndrome protein homolog 0.0027 0.0419 0.0697
Toxoplasma gondii thioredoxin reductase 0.0158 0.3046 1
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0015 0.0179 0.0587
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.0107 0.0093
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0398 0.0665
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0398 0.1305
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0378 0.0414
Trypanosoma cruzi NADH dehydrogenase, putative 0.0015 0.0179 0.0587
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0055 0.0983 0.1704
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3226
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0055 0.0983 0.1129
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0015 0.0179 0.0177
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0029 0.0025
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0029 0.0025
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0015 0.0179 0.0268
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0299 0.0895
Echinococcus granulosus bloom syndrome protein 0.0027 0.0419 0.0462
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0029 0.0025
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0179 0.0275
Schistosoma mansoni nuclear hormone receptor 0.001 0.0086 0.0086
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0983 0.3226
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0015 0.0179 0.019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0055 0.0983 0.0983
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0086 0.0102
Plasmodium falciparum flap endonuclease 1 0.0025 0.0398 0.1222
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0305 0.0543
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0029 0.0052
Schistosoma mansoni coup transcription factor 0.001 0.0086 0.0086
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0299 0.0482
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0179 0.0275
Leishmania major trypanothione reductase 0.0158 0.3046 1
Schistosoma mansoni bromodomain containing protein 0.0006 0.0009 0.0009
Trypanosoma brucei ISWI complex protein 0.0015 0.0198 0.0558
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0015 0.0179 0.0275
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0015 0.0179 0.4498
Schistosoma mansoni ap endonuclease 0.0021 0.0299 0.0299
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0029 0.0095
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0158 0.3046 0.3851
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0378 0.0378
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0367 0.1122
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0015 0.0179 0.0177
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0029 0.0052
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0015 0.0179 0.019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0299 0.0982
Trichomonas vaginalis DNA helicase recq1, putative 0.0027 0.0419 0.0703
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0015 0.0179 0.0496
Brugia malayi hypothetical protein 0.0025 0.0381 0.0629
Loa Loa (eye worm) hypothetical protein 0.0007 0.0029 0.0052
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0179 0.0496
Trichomonas vaginalis glutaminase, putative 0.0287 0.5625 1
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0015 0.0179 0.0177
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0015 0.0179 0.0177
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0398 0.1222
Loa Loa (eye worm) hypothetical protein 0.0015 0.0179 0.0318
Loa Loa (eye worm) hypothetical protein 0.0018 0.0246 0.0438
Echinococcus multilocularis dnaJ subfamily B 0.0429 0.8472 1
Mycobacterium ulcerans dehydrogenase 0.0015 0.0179 0.0268
Schistosoma mansoni glutamate synthase 0.0015 0.0179 0.0179
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0086 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0086 0.0102
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0015 0.0179 0.0587
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0086 0.0086
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0038 0.0011
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.001 0.0086 0.0153
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0246 0.0841
Loa Loa (eye worm) glutaminase 2 0.0287 0.5625 1
Loa Loa (eye worm) RecQ helicase 0.0027 0.0419 0.0745
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0398 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0038 0.0011
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0029 0.0095
Plasmodium falciparum glutathione reductase 0.0158 0.3046 1
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0381 0.1167
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0172 0.0564
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0179 0.0179
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0227 0.0276
Mycobacterium ulcerans monoxygenase 0.0015 0.0179 0.0268
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0299 0.1495
Schistosoma mansoni cpg binding protein 0.0034 0.0564 0.0564
Mycobacterium ulcerans glutaminase 0.0287 0.5625 1
Loa Loa (eye worm) oxidoreductase 0.0007 0.0029 0.0052
Onchocerca volvulus 0.0024 0.0367 0.7325
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0367 0.0605
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0086 0.0086
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0086 0.0067
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0015 0.0179 0.0268
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0029 0.0025
Trypanosoma cruzi ISWI complex protein 0.0015 0.0198 0.0649
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.004 0.0692 0.1185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0086 0.0153
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0233 0.0242
Echinococcus granulosus zinc finger protein 0.0022 0.0318 0.0343
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0086 0.0067
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0075 0.0054
Mycobacterium tuberculosis Probable oxidoreductase 0.04 0.7895 1
Echinococcus multilocularis geminin 0.0185 0.3588 0.4215
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0086 0.0067
Onchocerca volvulus 0.0015 0.0179 0.3241
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0025 0.00000000016123
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0055 0.0983 0.1704
Mycobacterium ulcerans hypothetical protein 0.0024 0.0367 0.0605
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3226
Leishmania major hypothetical protein, conserved 0.0015 0.0179 0.0496
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0354 0.1078
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0179 0.0496
Loa Loa (eye worm) hypothetical protein 0.0018 0.0246 0.0438
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0086 0.1233
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0367 0.0605
Toxoplasma gondii NADPH-glutathione reductase 0.0055 0.0983 0.3226
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0015 0.0179 0.0177
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0015 0.0179 0.0215
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0299 0.3043
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.036 0.7091 0.8981
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0055 0.0983 0.3161
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0055 0.0983 0.3226
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0086 0.0086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0227 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0086 0.0102
Schistosoma mansoni hypothetical protein 0.0011 0.0109 0.0109
Echinococcus multilocularis thioredoxin glutathione reductase 0.016 0.3088 0.3623
Schistosoma mansoni hypothetical protein 0.0015 0.0198 0.0198
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0172 0.0473
Schistosoma mansoni zinc finger protein 0.0022 0.0318 0.0318
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.1129 0.1303
Brugia malayi Flap endonuclease-1 0.0025 0.0398 0.0659
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0179 0.0275
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0109 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0246 0.0438
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3161
Brugia malayi hypothetical protein 0.0016 0.0207 0.0317
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.0107 0.0093
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0086 0.1233
Trypanosoma cruzi ISWI complex protein 0.0015 0.0198 0.0649
Schistosoma mansoni disulfide oxidoreductase 0.0015 0.0179 0.0179
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0983 0.3226
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0029 0.0007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0086 0.0067
Schistosoma mansoni zinc finger protein 0.0015 0.0198 0.0198
Plasmodium vivax glutathione reductase, putative 0.0158 0.3046 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0086 0.0086
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0378 0.0414
Trichomonas vaginalis apoptosis inducing factor, putative 0.0015 0.0179 0.0275
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0029 0.0025
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0179 0.0275
Schistosoma mansoni cpg binding protein 0.0034 0.0564 0.0564
Plasmodium falciparum thioredoxin reductase 0.0055 0.0983 0.3161
Schistosoma mansoni bromodomain containing protein 0.0066 0.1201 0.1201
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0086 0.0067
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0055 0.0983 0.1234
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0179 0.0275
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.04 0.7895 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0233 0.0242
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0086 0.0067
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0015 0.0179 0.0496
Loa Loa (eye worm) hypothetical protein 0.0041 0.0712 0.1265
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0179 0.0268
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0086 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0086 0.0153
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0614 0.0693
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0179 0.0587
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0086 0.0153
Treponema pallidum thioredoxin reductase (trxB) 0.0015 0.0179 0.182
Plasmodium falciparum thioredoxin reductase 0.0158 0.3046 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0367 0.043
Loa Loa (eye worm) hypothetical protein 0.0134 0.2558 0.4548
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0015 0.0179 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0086 0.0067
Giardia lamblia Glutamate synthase 0.0015 0.0179 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0086 0.0102
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0018 0.0247 0.0723
Loa Loa (eye worm) hypothetical protein 0.0024 0.0367 0.0653
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0086 0.0102
Plasmodium falciparum glutathione reductase 0.0055 0.0983 0.3161
Onchocerca volvulus 0.003 0.0491 1
Leishmania major NADH dehydrogenase, putative 0.0015 0.0179 0.0496
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0086 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0367 0.1122
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0055 0.0983 0.3161
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0307 0.0307
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0055 0.0983 0.3226
Leishmania major hypothetical protein, conserved 0.0015 0.0179 0.0496
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0299 0.032
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0029 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0025 0.00000000016123
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0086 0.0067
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0015 0.0179 0.0587
Schistosoma mansoni flap endonuclease-1 0.0023 0.0349 0.0349
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0029 0.0095
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0179 0.0275

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.