Detailed information for compound 1094156

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 424.233 | Formula: C17H17IN2O3
  • H donors: 3 H acceptors: 3 LogP: 3.32 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: Ic1ccc(c(c1)/C=N/CCCNC(=O)c1ccccc1O)O
  • InChi: 1S/C17H17IN2O3/c18-13-6-7-15(21)12(10-13)11-19-8-3-9-20-17(23)14-4-1-2-5-16(14)22/h1-2,4-7,10-11,21-22H,3,8-9H2,(H,20,23)/b19-11+
  • InChiKey: GXTYWCQCGLCDRP-YBFXNURJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli 3-oxoacyl-[acyl-carrier-protein] synthase III Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Chlamydia trachomatis oxoacyl-ACP synthase III Get druggable targets OG5_129509 All targets in OG5_129509
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) Get druggable targets OG5_129509 All targets in OG5_129509
Mycobacterium ulcerans 3-oxoacyl-ACP synthase Get druggable targets OG5_129509 All targets in OG5_129509
Plasmodium knowlesi beta-ketoacyl-acyl carrier protein synthase III precursor, putative Get druggable targets OG5_129509 All targets in OG5_129509
Mycobacterium ulcerans 3-oxoacyl-ACP synthase Get druggable targets OG5_129509 All targets in OG5_129509
Neospora caninum 3-oxoacyl-(acyl-carrier-protein) synthase III family protein, putative Get druggable targets OG5_129509 All targets in OG5_129509
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative Get druggable targets OG5_129509 All targets in OG5_129509
Plasmodium falciparum beta-ketoacyl-ACP synthase III Get druggable targets OG5_129509 All targets in OG5_129509
Mycobacterium ulcerans beta-ketoacyl synthase-like protein Get druggable targets OG5_129509 All targets in OG5_129509
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase Get druggable targets OG5_129509 All targets in OG5_129509
Plasmodium berghei apicoplast beta-ketoacyl-acyl carrier protein synthase III precursor, putative Get druggable targets OG5_129509 All targets in OG5_129509
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Conserved hypothetical protein 3-oxoacyl-[acyl-carrier-protein] synthase III 317 aa 265 aa 26.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1417 0.3416
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0346 0.0304
Brugia malayi 6-phosphofructokinase 0.0122 0.1417 0.4918
Echinococcus granulosus lysosomal alpha glucosidase 0.0182 0.2218 0.2183
Echinococcus multilocularis dna polymerase eta 0.0088 0.0972 0.0932
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0346 0.0814
Trypanosoma brucei DNA polymerase IV, putative 0.0089 0.0989 0.2294
Trypanosoma cruzi DNA polymerase eta, putative 0.0088 0.0972 0.2255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0306 0.0715
Brugia malayi beta-lactamase 0.0035 0.0272 0.0945
Loa Loa (eye worm) RecQ helicase 0.0022 0.0105 0.0276
Schistosoma mansoni survival motor neuron protein 0.0047 0.0438 0.0396
Entamoeba histolytica fatty acid elongase, putative 0.005 0.0469 0.1112
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Echinococcus granulosus snurportin 1 0.0303 0.3807 0.378
Echinococcus granulosus dna polymerase eta 0.0088 0.0972 0.0932
Schistosoma mansoni lipoxygenase 0.0255 0.3184 0.3153
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0246 0.3038
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0346 0.0814
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0272 0.0613
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0122 0.1417 0.6947
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1417 0.3416
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0045 0.0001
Schistosoma mansoni DNA helicase recq5 0.0022 0.0105 0.0061
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0044 0.0116
Trypanosoma brucei DNA polymerase IV, putative 0.0082 0.0891 0.2065
Echinococcus granulosus neuropeptide s receptor 0.0517 0.6639 0.6624
Brugia malayi Doublecortin family protein 0.0066 0.0686 0.238
Loa Loa (eye worm) hypothetical protein 0.0035 0.0272 0.0715
Loa Loa (eye worm) hypothetical protein 0.0066 0.0686 0.1801
Echinococcus granulosus importin subunit beta 1 0.0028 0.0187 0.0143
Brugia malayi jmjC domain containing protein 0.0066 0.0681 0.2363
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.016 0.192 0.3586
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.003
Echinococcus granulosus histone acetyltransferase MYST2 0.0061 0.0614 0.0573
Plasmodium vivax multidomain scavenger receptor, putative 0.0066 0.0686 0.133
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0116 0.0246
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0346 0.0814
Brugia malayi hypothetical protein 0.0066 0.0686 0.238
Loa Loa (eye worm) doublecortin family protein 0.0066 0.0686 0.1801
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0272 0.0473
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0116 0.0254
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0061 0.0614 0.2131
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0272 0.0229
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0383 0.4868 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0548 0.1441
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0182 0.2213 0.2179
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0709 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0059 0.0596 0.0704
Brugia malayi polk-prov protein 0.0048 0.0448 0.1556
Echinococcus multilocularis neuropeptide s receptor 0.0517 0.6639 0.6624
Schistosoma mansoni alpha-glucosidase 0.0157 0.1883 0.1847
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0105 0.022
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0045 0.0001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0105 0.0918
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0686 0.0645
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0448 0.1026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0383 0.4868 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0045 0.0001
Treponema pallidum fructose-bisphosphate aldolase 0.0327 0.4127 1
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0596 0.2068
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1417 0.3416
Schistosoma mansoni hypothetical protein 0.0066 0.0686 0.0645
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0358 0.0316
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0686 0.0645
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0681 0.064
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0056 0.0104
Brugia malayi beta-lactamase family protein 0.0035 0.0272 0.0945
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0122 0.1417 0.3017
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1417 0.3416
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0088 0.0305
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0346 0.0814
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0088 0.0091
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0045 0.0157
Brugia malayi mbt repeat family protein 0.0053 0.0517 0.1793
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0438 0.1522
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0272 0.0229
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0346 0.0814
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0044 0.0077
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0088 0.0091
Trypanosoma brucei unspecified product 0.0082 0.0891 0.2065
Schistosoma mansoni hypothetical protein 0.0324 0.4093 0.4067
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Schistosoma mansoni terminal deoxycytidyl transferase 0.0059 0.0596 0.0554
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.4127 1
Echinococcus multilocularis expressed protein 0.0037 0.0306 0.0263
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0056 0.0104
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0116 0.0254
Schistosoma mansoni hypothetical protein 0.0018 0.0045 0.0001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0105 0.0918
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0412
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0105 0.0228
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0548 0.1441
Schistosoma mansoni microtubule-associated protein tau 0.0772 1 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0089 0.0989 0.2374
Trypanosoma brucei unspecified product 0.0041 0.0353 0.0802
Toxoplasma gondii ABC1 family protein 0.0035 0.0272 0.3432
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0397 0.0354
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0397 0.0354
Loa Loa (eye worm) hypothetical protein 0.0035 0.0272 0.0715
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.4127 1
Trypanosoma brucei glucosidase, putative 0.004 0.0346 0.0786
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0056 0.0175
Brugia malayi RNA, U transporter 1 0.0081 0.0877 0.3042
Schistosoma mansoni myelin transcription factor 1 myt1 0.0061 0.0614 0.0573
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0272 0.0613
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Schistosoma mansoni hypothetical protein 0.0018 0.0045 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0397 0.1376
Loa Loa (eye worm) hypothetical protein 0.0038 0.0316 0.0829
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0709 0.0668
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Loa Loa (eye worm) hypothetical protein 0.0066 0.0686 0.1801
Schistosoma mansoni hypothetical protein 0.0018 0.0045 0.0001
Schistosoma mansoni hypothetical protein 0.0303 0.3807 0.378
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0358 0.0815
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0439 0.1005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0272 0.0229
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0162 0.0427
Loa Loa (eye worm) hypothetical protein 0.0061 0.0614 0.1613
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0358 0.0843
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0056 0.0104
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0056 0.0104
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0686 0.0645
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0056 0.0024
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0709 0.095
Schistosoma mansoni alpha-glucosidase 0.0157 0.1883 0.1847
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0026 0.0153 0.164
Schistosoma mansoni importin beta-1 0.0028 0.0187 0.0143
Mycobacterium tuberculosis Conserved hypothetical protein 0.0178 0.2161 0.411
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0316 0.1095
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0044 0.0077
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0358 0.0744
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0294 0.0664
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0681 0.1788
Echinococcus multilocularis GPCR, family 2 0.0018 0.0045 0.0001
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0056 0.0024
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0246 0.0419
Entamoeba histolytica fatty acid elongase, putative 0.005 0.0469 0.1112
Echinococcus multilocularis alkaline phosphatase 0.0182 0.2213 0.2179
Loa Loa (eye worm) hypothetical protein 0.0018 0.0044 0.0116
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0517 0.0475
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Loa Loa (eye worm) hypothetical protein 0.0202 0.2478 0.6507
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0358 0.0815
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0272 0.045
Echinococcus multilocularis lysine specific demethylase 5A 0.0066 0.0681 0.064
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0272 0.0634
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0246 0.057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0346 0.0814
Onchocerca volvulus 0.0053 0.0517 0.2049
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0105 0.0127
Echinococcus granulosus intestinal type alkaline phosphatase 0.0182 0.2213 0.2179
Loa Loa (eye worm) hypothetical protein 0.0026 0.0156 0.041
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0383 0.4868 1
Schistosoma mansoni lipoxygenase 0.0136 0.1612 0.1575
Echinococcus multilocularis histone acetyltransferase MYST2 0.0061 0.0614 0.0573
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0397 0.0354
Mycobacterium ulcerans hypothetical protein 0.0035 0.0272 0.045
Echinococcus multilocularis 6 phosphofructokinase 0.0122 0.1417 0.1379
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0681 0.064
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0105 0.0228
Brugia malayi mbt repeat family protein 0.0053 0.0517 0.1793
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0272 0.0634
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0346 0.0814
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0681 0.064
Echinococcus granulosus RUN 0.0066 0.0686 0.0645
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0182 0.2213 0.2179
Schistosoma mansoni hypothetical protein 0.0018 0.0045 0.0001
Echinococcus granulosus alkaline phosphatase 0.0182 0.2213 0.2179
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0358 0.0815
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0162 0.0564
Entamoeba histolytica Ran family GTPase 0.0021 0.0088 0.0186
Echinococcus granulosus GPCR family 2 0.0018 0.0045 0.0001
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0383 0.4868 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0517 0.1357
Echinococcus multilocularis RUN 0.0066 0.0686 0.0645
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0116 0.0254
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0056 0.0104
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0346 0.0814
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0105 0.0365
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.1417 0.33
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0397 0.0354
Echinococcus multilocularis lamin 0.0027 0.0162 0.0119
Brugia malayi jmjC domain containing protein 0.0018 0.0044 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.0693 0.1601
Echinococcus granulosus lamin dm0 0.0027 0.0162 0.0119
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0709 0.0668
Brugia malayi jmjC domain containing protein 0.0018 0.0044 0.0153
Onchocerca volvulus 0.0105 0.1204 0.4834
Loa Loa (eye worm) MBCTL1 0.0061 0.0614 0.1613
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0338 0.4271 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0358 0.0941
Onchocerca volvulus 0.0066 0.0686 0.2735
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0346 0.0814
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0056 0.0012
Onchocerca volvulus 0.0027 0.0162 0.0613
Brugia malayi hypothetical protein 0.0066 0.0686 0.238
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0044 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0119
Schistosoma mansoni alkaline phosphatase 0.0182 0.2213 0.2179
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0272 0.0945
Plasmodium falciparum LCCL domain-containing protein 0.0066 0.0686 0.133
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1417 0.3416
Schistosoma mansoni lamin 0.0027 0.0162 0.0119
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0067 0.0693 0.1601
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1417 0.3416
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0272 0.0634
Schistosoma mansoni rab6-interacting 0.0066 0.0686 0.0645
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0105 0.0365
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0011 0.0039
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0358 0.0843
Schistosoma mansoni ran 0.0021 0.0088 0.0044
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0548 0.1903
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0187 0.2146
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0709 0.1357
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.2881 0.285
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0397 0.1042
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0439 0.1005
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0105 0.0061
Echinococcus multilocularis snurportin 1 0.0303 0.3807 0.378
Echinococcus granulosus expressed protein 0.0037 0.0306 0.0263
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.1417 0.3722
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0105 0.0061
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0105 0.0061
Echinococcus granulosus 6 phosphofructokinase 0.0122 0.1417 0.1379
Onchocerca volvulus 0.0035 0.0272 0.1058
Echinococcus granulosus lamin 0.0027 0.0162 0.0119
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0432 0.5831
Echinococcus multilocularis neuropeptide receptor A26 0.0517 0.6639 0.6624
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0517 0.0475
Mycobacterium ulcerans 6-phosphofructokinase 0.0122 0.1417 0.2829
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0358 0.0843
Mycobacterium ulcerans hypothetical protein 0.0178 0.2161 0.4375
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.275 0.5391
Echinococcus multilocularis musashi 0.0027 0.0162 0.0119
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0358 0.0316
Brugia malayi 6-phosphofructokinase 0.0122 0.1417 0.4918
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0358 0.0316
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0088 0.018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Leishmania major importin beta-1 subunit, putative 0.0023 0.0116 0.0246
Loa Loa (eye worm) hypothetical protein 0.0088 0.0972 0.2553
Loa Loa (eye worm) hypothetical protein 0.0035 0.0272 0.0715
Loa Loa (eye worm) hypothetical protein 0.0028 0.0187 0.049
Loa Loa (eye worm) beta-lactamase 0.0035 0.0272 0.0715
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.2218 0.2183
Brugia malayi jmjC domain containing protein 0.0018 0.0044 0.0153
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0105 0.022
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0346 0.1202
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0358 0.0316
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0182 0.2213 0.2179
Leishmania major DNA polymerase kappa, putative 0.0067 0.0693 0.1601
Brugia malayi ImpB/MucB/SamB family protein 0.0088 0.0972 0.3374
Leishmania major DNA polymerase kappa, putative 0.0018 0.0056 0.0104
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0517 0.1357
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0577 0.1327
Brugia malayi hypothetical protein 0.0233 0.2881 1
Schistosoma mansoni rab6-interacting 0.0066 0.0686 0.0645
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0383 0.4868 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0338 0.4271 1
Echinococcus granulosus neuropeptide receptor A26 0.0517 0.6639 0.6624
Entamoeba histolytica fatty acid elongase, putative 0.005 0.0469 0.1112
Schistosoma mansoni ran 0.0021 0.0088 0.0044
Onchocerca volvulus 0.0027 0.0162 0.0613
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0246 0.0468
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0294 0.3759
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0105 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0246 0.057
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0182 0.2218 0.5825
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.016 0.1923 0.4487
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0397 0.0354
Trichomonas vaginalis rotamase, putative 0.0037 0.0306 0.0715
Schistosoma mansoni polycystin 1-related 0.0066 0.0686 0.0645
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.2881 0.285
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0105 0.0061
Brugia malayi jmjC domain containing protein 0.0066 0.0681 0.2363
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0346 0.0786
Leishmania major mitochondrial DNA polymerase beta 0.0338 0.4271 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0346 0.4545
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0294 0.0664
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0246 0.057
Onchocerca volvulus 0.0066 0.0686 0.2735
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0182 0.2213 0.2179
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0517 0.2049
Loa Loa (eye worm) phosphofructokinase 0.0122 0.1417 0.3722
Schistosoma mansoni DNA helicase recq1 0.0022 0.0105 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0246 0.057
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0358 0.0843
Leishmania major GTP-binding protein, putative 0.0021 0.0088 0.018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0059 0.0596 0.0554
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0246 0.0419
Loa Loa (eye worm) hypothetical protein 0.0035 0.0272 0.0715
Schistosoma mansoni hypothetical protein 0.0047 0.0438 0.0396
Echinococcus granulosus dna polymerase kappa 0.0089 0.0989 0.0949
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0059 0.0596 0.1565
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0059 0.0596 0.0554
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0246 0.057
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.3807 1
Leishmania major hypothetical protein, conserved 0.0035 0.0272 0.0613
Trypanosoma brucei unspecified product 0.0041 0.0353 0.0802
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0358 0.0815
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0358 0.0316
Loa Loa (eye worm) hypothetical protein 0.0018 0.0044 0.0116
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0686 0.0645
Brugia malayi beta-lactamase family protein 0.0035 0.0272 0.0945
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0358 0.1244
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0056 0.0104
Loa Loa (eye worm) hypothetical protein 0.0233 0.2881 0.7568
Echinococcus multilocularis Polycystic kidney disease protein 0.0066 0.0686 0.0645
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0066 0.0681 0.064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0272 0.0715
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0439 0.1005
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0294 0.0664
Trypanosoma brucei DNA polymerase eta, putative 0.0088 0.0972 0.2255
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0255 0.3184 0.3153
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0246 0.3038
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0246 0.0419
Loa Loa (eye worm) hypothetical protein 0.0048 0.0448 0.1177
Mycobacterium ulcerans DNA polymerase IV 0.0089 0.0989 0.1939
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.045 0.103
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0202 0.2478 1
Echinococcus multilocularis lamin dm0 0.0027 0.0162 0.0119
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0105 0.0365
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0272 0.0229
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0246 0.057
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0044 0.0116
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0272 0.0634
Schistosoma mansoni rotamase 0.0037 0.0306 0.0263
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.1417 0.33
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0272 0.0715
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.016 0.1923 0.4487
Mycobacterium ulcerans beta-lactamase 0.0035 0.0272 0.045
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0346 0.0814
Leishmania major DNA polymerase eta, putative 0.0047 0.0432 0.0987
Schistosoma mansoni hypothetical protein 0.0095 0.106 0.102
Loa Loa (eye worm) hypothetical protein 0.0018 0.0044 0.0116
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0088 0.0231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0397 0.0354
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0709 0.1638
Schistosoma mansoni lamin 0.0027 0.0162 0.0119
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0709 0.1357
Schistosoma mansoni alkaline phosphatase 0.0182 0.2213 0.2179
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0517 0.0475
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0162 0.0427
Onchocerca volvulus 0.0047 0.0438 0.1732
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0246 0.0419
Loa Loa (eye worm) hypothetical protein 0.0035 0.0272 0.0715
Giardia lamblia DINP protein human, muc B family 0.0067 0.0693 0.1566
Echinococcus multilocularis dna polymerase kappa 0.0089 0.0989 0.0949
Entamoeba histolytica deoxycytidyl transferase, putative 0.0059 0.0596 0.1421
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0105 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0272 0.0613
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.045 0.103
Schistosoma mansoni loxhd1 0.0066 0.0686 0.0645
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0358 0.0316
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0346 0.0786
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0105 0.022
Trichomonas vaginalis rotamase, putative 0.0036 0.0294 0.0687
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0517 0.0475
Loa Loa (eye worm) hypothetical protein 0.0027 0.0162 0.0427
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0272 0.0634
Giardia lamblia Fructose-bisphosphate aldolase 0.0327 0.4127 1
Entamoeba histolytica hypothetical protein 0.0023 0.0116 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0448 0.1026
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0246 0.057
Trichomonas vaginalis esterase, putative 0.0035 0.0272 0.0634
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.016 0.192 0.3875
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0044 0.0116
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0255 0.3184 0.3153
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0306 0.0803
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0306 0.1061
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0105 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Mycobacterium ulcerans DNA polymerase IV 0.0089 0.0989 0.1939
Schistosoma mansoni hypothetical protein 0.0038 0.0316 0.0273
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0045 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.4127 1
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0056 0.0104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0709 0.1357
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0105 0.0228
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0548 0.1903
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0383 0.4868 1
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0182 0.2213 0.2179
Echinococcus multilocularis microtubule associated protein 2 0.0772 1 1
Entamoeba histolytica fatty acid elongase, putative 0.005 0.0469 0.1112
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0056 0.0104
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0517 0.0475
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.1417 0.1379
Plasmodium falciparum importin beta, putative 0.0028 0.0187 0.0296
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0105 0.0061
Brugia malayi jmjC domain containing protein 0.0018 0.0044 0.0153
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0412
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0045 0.0157
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0088 0.018
Trichomonas vaginalis ran, putative 0.0021 0.0088 0.0186
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0187 0.0143
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0338 0.4271 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0432 0.0987
Leishmania major ATP-dependent phosphofructokinase 0.0122 0.1417 0.33
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0246 0.057
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0294 0.0687
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0517 0.0475
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0709 0.0668
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0061 0.0614 0.0573
Brugia malayi intermediate filament protein 0.0027 0.0162 0.0564
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.016 0.192 1
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0105 0.0228
Brugia malayi N-terminal motif family protein 0.0202 0.2478 0.8599
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0088 0.0044
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0358 0.0316
Trypanosoma brucei DNA polymerase IV, putative 0.0089 0.0989 0.2294
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0246 0.3038
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1417 0.3416
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0346 0.0909
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0088 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0989 0.2294
Schistosoma mansoni intermediate filament proteins 0.0027 0.0162 0.0119
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0517 0.0475
Schistosoma mansoni DNA polymerase eta 0.0088 0.0972 0.0932
Entamoeba histolytica fatty acid elongase, putative 0.005 0.0469 0.1112
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0089 0.0989 0.2374
Onchocerca volvulus 0.0035 0.0272 0.1058
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0709 0.0668
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0045 0.0119
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0066 0.0681 0.064
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0088 0.018
Brugia malayi Glycosyl hydrolases family 31 protein 0.0182 0.2218 0.7697
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.2218 0.2183
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0056 0.0104
Brugia malayi phosphofructokinase 0.0122 0.1417 0.4918
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0346 0.0786
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0088 0.066
Leishmania major DNA polymerase eta, putative 0.0088 0.0972 0.2255
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0346 0.0814
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0358 0.0316
Echinococcus granulosus bloom syndrome protein 0.0022 0.0105 0.0061
Echinococcus granulosus endonuclease exonuclease phosphatase 0.021 0.2587 0.2555
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0383 0.4868 1
Plasmodium vivax importin-beta 2, putative 0.0028 0.0187 0.0296
Brugia malayi Importin beta-1 subunit 0.0028 0.0187 0.0648
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.016 0.1923 0.4487
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.021 0.2587 0.2555
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0439 0.1005
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0122 0.1417 0.2491
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.1417 0.3722
Echinococcus granulosus intermediate filament protein 0.0027 0.0162 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.045 0.103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0397 0.0354
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0346 0.0304
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0088 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0105 0.0276
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0061 0.0614 0.0573
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0294 0.0664
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0059 0.0596 0.0554
Schistosoma mansoni alpha glucosidase 0.004 0.0346 0.0304
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0067 0.0693 0.0916
Mycobacterium ulcerans lipase LipD 0.0035 0.0272 0.045
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0681 0.064
Echinococcus granulosus Polycystic kidney disease protein 0.0066 0.0686 0.0645
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0383 0.4868 0.5
Onchocerca volvulus 0.0035 0.0272 0.1058
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.1417 0.1379
Leishmania major hypothetical protein, conserved 0.0018 0.0044 0.0077
Leishmania major DNA damage repair protein, putative 0.0018 0.0056 0.0104
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0272 0.045
Toxoplasma gondii hypothetical protein 0.0054 0.0532 0.7334

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.5 ug ml-1 Inhibition of Escherichia coli Beta-ketoacyl-ACP synthase III expressed in Escherichia coli BL21 (DE3) by liquid scintillation counting ChEMBL. 19884012
MIC (functional) = 3.13 ug ml-1 Antimicrobial activity against Escherichia coli ATCC 35218 after 24 hrs by MTT assay ChEMBL. 19884012

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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