Detailed information for compound 1097628

Basic information

Technical information
  • TDR Targets ID: 1097628
  • Name: 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[ 2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4- methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl ]amino]butanoic acid
  • MW: 631.59 | Formula: C32H30F5N3O5
  • H donors: 2 H acceptors: 4 LogP: 2.63 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cccc(c1F)c1c(=O)n(C[C@@H](c2ccccc2)NCCCC(=O)O)c(=O)n(c1C)Cc1c(F)cccc1C(F)(F)F
  • InChi: 1S/C32H30F5N3O5/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42)/t25-/m0/s1
  • InChiKey: HEAUOKZIVMZVQL-VWLOTQADSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[[(1R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxo-pyrimidin-1-yl]-1-phenyl-ethyl]amino]butanoic acid
  • 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxo-1-pyrimidinyl]-1-phenylethyl]amino]butanoic acid
  • 4-[[(1R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-[2-fluoro-6-(trifluoromethyl)benzyl]-2,6-diketo-4-methyl-pyrimidin-1-yl]-1-phenyl-ethyl]amino]butyric acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0052 0.0064 0.0199
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0389
Onchocerca volvulus 0.005 0.0061 0.0424
Onchocerca volvulus 0.0038 0.0035 0.0245
Schistosoma mansoni phospholipase A-2-activating protein 0.0028 0.0015 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0045 0.0593
Trypanosoma brucei phosphoglycerate kinase 0.0276 0.0519 0.1026
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0101 0.0163 0.0618
Brugia malayi jmjC domain containing protein 0.0041 0.0042 0.0124
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0052 0.0164
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0042 0.0148
Trichomonas vaginalis rotamase, putative 0.0033 0.0025 0.0079
Brugia malayi MH1 domain containing protein 0.0027 0.0013 0.0037
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0159 0.0282 0.0879
Schistosoma mansoni ets-related 0.0219 0.0403 0.0515
Echinococcus granulosus leucyl aminopeptidase 0.0047 0.0055 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Echinococcus multilocularis leucyl aminopeptidase 0.0047 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0013 0.004
Schistosoma mansoni gabp alpha 0.0072 0.0105 0.0134
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0229 0.0425 0.1499
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0009 0.0011
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0018 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0111 0.0184 0.0235
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0027 0.0013 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Schistosoma mansoni smad1 5 8 and 0.0027 0.0013 0.0016
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0229 0.0425 0.0425
Schistosoma mansoni SET domain protein 0.0039 0.0038 0.0048
Trichomonas vaginalis ferritin, putative 0.0027 0.0013 0.004
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0069 0.0214
Schistosoma mansoni ferritin 0.0027 0.0013 0.0016
Echinococcus granulosus histone acetyltransferase MYST2 0.0175 0.0315 0.0403
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0015 0.0048
Mycobacterium ulcerans acetyl-CoA synthetase 0.0029 0.0018 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0018 0.0058
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0007 0.0023
Schistosoma mansoni hypothetical protein 0.0147 0.0258 0.0329
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0042 0.0148
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0059 0.0176
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Onchocerca volvulus 0.0052 0.0064 0.0441
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0013 0.0045
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0174 0.1054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0248 0.0464 0.1714
Echinococcus granulosus leucyl aminopeptidase 0.0047 0.0055 0.007
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0114 0.1465
Onchocerca volvulus 0.0147 0.0258 0.1788
Toxoplasma gondii heat shock protein HSP90 0.0068 0.0097 0.1238
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0276 0.0519 0.162
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0018 0.0054
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0094 0.012
Plasmodium vivax glutathione reductase, putative 0.0046 0.0053 0.1004
Mycobacterium ulcerans hypothetical protein 0.0083 0.0127 0.0436
Mycobacterium ulcerans leucyl aminopeptidase 0.0237 0.044 0.1622
Brugia malayi TAR-binding protein 0.0066 0.0093 0.0276
Plasmodium vivax acyl-CoA synthetase, putative 0.0075 0.011 0.2092
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0282 0.0834
Toxoplasma gondii histone lysine methyltransferase SET1 0.0071 0.0102 0.1308
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0041 0.0042 0.0538
Giardia lamblia DNA damage repair protein 0.0083 0.0127 0.0398
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0254 0.0325
Echinococcus multilocularis lysosomal alpha glucosidase 0.0716 0.1414 0.1414
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0025 0.0089
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0029 0.0018 0.0021
Trypanosoma cruzi heat shock protein 90, putative 0.0068 0.0097 0.0191
Plasmodium falciparum heat shock protein 90 0.0068 0.0097 0.128
Schistosoma mansoni hypothetical protein 0.0957 0.1905 0.2433
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.3872 0.783 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.003
Echinococcus multilocularis leucine aminopeptidase protein 0.0237 0.044 0.044
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.012 0.0202 0.063
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0358
Mycobacterium tuberculosis Conserved protein 0.0038 0.0035 0.0133
Schistosoma mansoni transcription factor LCR-F1 0.0157 0.0277 0.0354
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0079 0.0247
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.018 0.0324 0.064
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0052 0.0064 0.0224
Mycobacterium ulcerans hypothetical protein 0.0038 0.0035 0.0085
Brugia malayi hypothetical protein 0.0025 0.0009 0.0025
Onchocerca volvulus 0.01 0.0161 0.112
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0028 0.0015 0.0048
Schistosoma mansoni chromobox protein 0.0074 0.0109 0.014
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0018 0.0069
Mycobacterium ulcerans phosphoglycerate kinase 0.0276 0.0519 0.1922
Echinococcus multilocularis intestinal type alkaline phosphatase 0.3872 0.783 0.783
Schistosoma mansoni DNA polymerase IV / kappa 0.0083 0.0127 0.0163
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Brugia malayi Endoplasmin precursor 0.0068 0.0097 0.0286
Leishmania major 4-coumarate:coa ligase-like protein 0.01 0.0161 0.0319
Brugia malayi mbt repeat family protein 0.0154 0.0272 0.0805
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0111 0.0184 0.065
Entamoeba histolytica hypothetical protein 0.0157 0.0277 0.0866
Brugia malayi follicle stimulating hormone receptor 0.026 0.0487 0.1442
Loa Loa (eye worm) beta-lactamase 0.0038 0.0035 0.0124
Echinococcus multilocularis FTZ F1 alpha 0.0046 0.0053 0.0053
Echinococcus granulosus cysteine protease 0.0027 0.0013 0.0016
Echinococcus granulosus neuropeptide receptor A26 0.0945 0.188 0.2401
Onchocerca volvulus Cathepsin F homolog 0.0052 0.0064 0.0441
Schistosoma mansoni DNA helicase recq5 0.0229 0.0425 0.0543
Trichomonas vaginalis DNA helicase recq, putative 0.0434 0.0841 0.2628
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0029 0.0018 0.0021
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0018 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0053 0.0157
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0052 0.0671
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0047 0.0055 0.0161
Trypanosoma brucei glucosidase, putative 0.0159 0.0282 0.0557
Plasmodium falciparum polyubiquitin binding protein, putative 0.0041 0.0043 0.0568
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0041 0.0042 0.0083
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0061 0.0317
Echinococcus multilocularis neuropeptide s receptor 0.0945 0.188 0.188
Echinococcus multilocularis Smad4 0.0027 0.0013 0.0013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0041 0.0042 0.0083
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0131 0.0168
Trichomonas vaginalis esterase, putative 0.0038 0.0035 0.011
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0041 0.0043 0.0134
Echinococcus granulosus ecdysone induced protein 78C 0.0046 0.0053 0.0068
Onchocerca volvulus Bile acid receptor homolog 0.0046 0.0053 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0046 0.0053 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Toxoplasma gondii ABC1 family protein 0.0038 0.0035 0.0449
Brugia malayi nuclear receptor RXR 0.0025 0.0009 0.0025
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0276 0.0519 0.1026
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0174 0.0656
Brugia malayi jmjC domain containing protein 0.0041 0.0042 0.0124
Brugia malayi MH2 domain containing protein 0.0027 0.0013 0.0037
Echinococcus multilocularis thyroid hormone receptor alpha 0.0046 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Trypanosoma brucei trypanothione reductase 0.0046 0.0053 0.0105
Echinococcus multilocularis JmjC domain containing protein 4 0.0041 0.0042 0.0042
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0053 0.0157
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.0447 0.1691
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0161 0.0565
Loa Loa (eye worm) hypothetical protein 0.025 0.0466 0.1644
Treponema pallidum ATP-dependent DNA helicase 0.0117 0.0196 0.0613
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0046 0.0053 0.0187
Brugia malayi chromobox protein homolog 3 0.0042 0.0043 0.0128
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0059 0.0076
Echinococcus multilocularis ecdysone induced protein 78C 0.0046 0.0053 0.0053
Onchocerca volvulus 0.0038 0.0035 0.0244
Brugia malayi Cathepsin L-like precursor 0.0052 0.0064 0.0188
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0047 0.0055 0.007
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0217 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.003
Schistosoma mansoni hypothetical protein 0.0157 0.0277 0.0354
Trypanosoma brucei PAB1-binding protein , putative 0.013 0.0223 0.044
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.01 0.0161 0.061
Schistosoma mansoni apoferritin-2 0.0027 0.0013 0.0016
Brugia malayi Cathepsin L-like cysteine proteinase 0.0035 0.0029 0.0086
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0053 0.0053
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0061 0.023
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0229 0.0425 0.1258
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0018 0.0054
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0641 0.1262 0.445
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0021 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0013 0.0025
Onchocerca volvulus 0.0052 0.0064 0.0441
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0112 0.035
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0046 0.0053 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Echinococcus multilocularis expressed protein 0.0027 0.0013 0.0013
Brugia malayi Inositol-1 0.0075 0.0112 0.0332
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0105 0.0105
Entamoeba histolytica acyl-CoA synthetase, putative 0.01 0.0161 0.0504
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0035 0.0045
Trichomonas vaginalis endoplasmin, putative 0.0042 0.0043 0.0135
Loa Loa (eye worm) hypothetical protein 0.0111 0.0185 0.0652
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.004 0.0125
Leishmania major phosphoglycerate kinase C, glycosomal 0.0276 0.0519 0.1026
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0041 0.0043 0.0085
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0101 0.0163 0.0573
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.0096 0.0363
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0029 0.0018 0.0021
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0013 0.0048
Brugia malayi hypothetical protein 0.0157 0.0277 0.082
Echinococcus multilocularis inositol monophosphatase 1 0.0075 0.0112 0.0112
Brugia malayi Cathepsin L-like precursor 0.0052 0.0064 0.0188
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Schistosoma mansoni polycystin 1-related 0.0147 0.0258 0.0329
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0229 0.0425 0.0425
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0018 0.0054
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0266 0.0266
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Toxoplasma gondii 3'-5' exonuclease domain-containing protein 0.0045 0.005 0.0642
Toxoplasma gondii heat shock protein 75, putative 0.0028 0.0015 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0013 0.0025
Leishmania major cathepsin L-like protease 0.0197 0.0358 0.0708
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0007 0.0023
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0268 0.0503 0.0642
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0035 0.0133
Trypanosoma cruzi heat shock protein, putative 0.0028 0.0015 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0029 0.009
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0101 0.0164 0.0325
Trypanosoma cruzi DNA damage repair protein, putative 0.0083 0.0127 0.0252
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.0003 0.0004
Onchocerca volvulus 0.0086 0.0134 0.0931
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0018 0.0069
Loa Loa (eye worm) heat shock protein 90 0.0068 0.0097 0.0341
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0045 0.085
Brugia malayi Cathepsin L-like precursor 0.0052 0.0064 0.0188
Brugia malayi tailless protein 0.0022 0.0003 0.0009
Echinococcus multilocularis neutral alpha glucosidase AB 0.0159 0.0282 0.0282
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.0003 0.0009
Toxoplasma gondii hypothetical protein 0.0026 0.0012 0.0158
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Brugia malayi jmjC domain containing protein 0.0041 0.0042 0.0124
Brugia malayi hypothetical protein 0.025 0.0466 0.138
Brugia malayi WD domain containing protein 0.0041 0.0043 0.0127
Schistosoma mansoni cathepsin F (C01 family) 0.0052 0.0064 0.0081
Echinococcus granulosus expressed protein 0.0027 0.0013 0.0016
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.0003 0.0003
Schistosoma mansoni importin beta-1 0.003 0.0019 0.0024
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0101 0.0163 0.0209
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0276 0.0519 0.1961
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0061 0.0061
Brugia malayi hypothetical protein 0.013 0.0223 0.0659
Plasmodium falciparum acyl-CoA synthetase 0.0075 0.011 0.1459
Echinococcus granulosus cathepsin l1 0.0052 0.0064 0.0081
Leishmania major cathepsin L-like protease 0.0197 0.0358 0.0708
Trypanosoma brucei Heat shock protein 83, putative 0.0068 0.0097 0.0191
Mycobacterium tuberculosis Probable ATP-dependent DNA helicase II UvrD2 0.0042 0.0045 0.0169
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0093 0.0119
Schistosoma mansoni protein phosphatase 2C 0.0041 0.0042 0.0054
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0149 0.1905
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0081 0.0123 0.0385
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0248 0.0464 0.0592
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0013 0.004
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0109 0.0342
Leishmania major 4-coumarate:coa ligase-like protein 0.01 0.0161 0.0319
Mycobacterium ulcerans beta-lactamase 0.0038 0.0035 0.0085
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0112 0.0187 0.3556
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0101 0.0164 0.0325
Echinococcus granulosus leucine aminopeptidase protein 0.0237 0.044 0.0562
Giardia lamblia Heat shock protein HSP 90-alpha 0.0054 0.0069 0.0214
Brugia malayi nuclear hormone receptor 0.0046 0.0053 0.0157
Brugia malayi beta-lactamase family protein 0.0038 0.0035 0.0104
Schistosoma mansoni Smad4 0.0027 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0154 0.0272 0.0959
Plasmodium vivax vivapain-2 0.0052 0.0064 0.1207
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0353 0.0676 0.1336
Trypanosoma cruzi DNA polymerase kappa, putative 0.0296 0.056 0.1107
Loa Loa (eye worm) WD domain-containing protein 0.0028 0.0015 0.0054
Leishmania major heat shock protein, putative 0.0028 0.0015 0.003
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0159 0.0282 0.0879
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.0124
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.004 0.0079
Giardia lamblia Phosphoglycerate kinase 0.0276 0.0519 0.162
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0052 0.0671
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0053 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0046 0.0053 0.0068
Mycobacterium tuberculosis Conserved protein 0.0038 0.0035 0.0133
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0099 0.0326
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0023 0.0081
Plasmodium falciparum thioredoxin reductase 0.0046 0.0053 0.07
Trypanosoma cruzi major cysteine proteinase, putative 0.0155 0.0273 0.0539
Schistosoma mansoni nuclear receptor 0.0022 0.0003 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.0461 0.0588
Brugia malayi Phosphoglycerate kinase 0.0276 0.0519 0.1536
Brugia malayi Latrophilin receptor protein 2 0.005 0.0059 0.0176
Onchocerca volvulus Huntingtin homolog 0.025 0.0466 0.3234
Schistosoma mansoni hypothetical protein 0.0264 0.0495 0.0632
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0272 0.0511 0.101
Loa Loa (eye worm) nuclear hormone receptor 0.0022 0.0003 0.0011
Onchocerca volvulus Protein ultraspiracle homolog 0.0046 0.0053 0.0368
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0018 0.0233
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Loa Loa (eye worm) RNA binding protein 0.0066 0.0093 0.0329
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0035 0.011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0102
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0054 0.0069 0.0136
Schistosoma mansoni hypothetical protein 0.1279 0.2559 0.3268
Echinococcus granulosus lipoxygenase domain containing protein 0.0147 0.0258 0.0329
Brugia malayi hypothetical protein 0.0147 0.0258 0.0763
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.043 0.0833 0.1646
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0039 0.0038 0.0038
Echinococcus multilocularis dna polymerase kappa 0.0296 0.056 0.056
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0277 0.0821
Schistosoma mansoni ferritin 0.0027 0.0013 0.0016
Onchocerca volvulus 0.0054 0.0069 0.0481
Trichomonas vaginalis set domain proteins, putative 0.0729 0.1441 0.4502
Echinococcus granulosus phospholipase A 2 activating protein 0.0041 0.0043 0.0055
Loa Loa (eye worm) hypothetical protein 0.0045 0.0051 0.018
Echinococcus granulosus heat shock protein 90 0.0068 0.0097 0.0123
Plasmodium falciparum DNA repair protein REV1, putative 0.0083 0.0127 0.1688
Brugia malayi glutathione reductase 0.0046 0.0053 0.0157
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0029 0.0018 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0021 0.0404
Schistosoma mansoni jumonji domain containing protein 0.0041 0.0042 0.0054
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0064
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0045 0.005 0.005
Schistosoma mansoni cpg binding protein 0.0035 0.0031 0.0039
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0079 0.0247
Brugia malayi hypothetical protein 0.0025 0.0009 0.0025
Brugia malayi Rhodanese-like domain containing protein 0.012 0.0202 0.0598
Leishmania major DNA damage repair protein, putative 0.0083 0.0127 0.0252
Loa Loa (eye worm) DR-78 0.0022 0.0003 0.0011
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.3872 0.783 1
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Echinococcus granulosus ferritin 0.0027 0.0013 0.0016
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0276 0.0519 0.6641
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.1187 0.2372 0.469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Loa Loa (eye worm) hypothetical protein 0.0092 0.0146 0.0516
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Schistosoma mansoni cpg binding protein 0.0032 0.0023 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0185 0.0366
Echinococcus multilocularis expressed protein 0.0033 0.0025 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0053 0.0068
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0018 0.0054
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0174 0.0656
Mycobacterium tuberculosis Conserved hypothetical protein 0.0268 0.0503 0.19
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0092 0.0146 0.0187
Schistosoma mansoni phosphoglycerate kinase 0.0276 0.0519 0.0662
Entamoeba histolytica heat shock protein 90, putative 0.0068 0.0097 0.0302
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Entamoeba histolytica rodhanase-like domain containing protein 0.012 0.0202 0.063
Toxoplasma gondii exonuclease III APE 0.0101 0.0163 0.2093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Schistosoma mansoni nuclear receptor 0.0022 0.0003 0.0004
Plasmodium vivax ataxin-2 like protein, putative 0.013 0.0223 0.4228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Onchocerca volvulus 0.0052 0.0064 0.0441
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0053 0.0157
Entamoeba histolytica cysteine proteinase 2 0.0027 0.0013 0.004
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0003 0.0009
Echinococcus multilocularis jumonji domain containing 1A 0.0041 0.0042 0.0042
Echinococcus multilocularis dnaJ subfamily C 6 0.0264 0.0495 0.0495
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0105 0.037
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0064 0.0126
Loa Loa (eye worm) hypothetical protein 0.012 0.0202 0.0712
Echinococcus granulosus cathepsin L cysteine protease 0.0027 0.0013 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0046 0.0053 0.0068
Loa Loa (eye worm) steroid hormone receptor 0.0046 0.0053 0.0187
Onchocerca volvulus 0.0033 0.0025 0.0173
Trypanosoma brucei chrX additional, unordered contigs 0.0083 0.0127 0.0252
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0131 0.0389
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0386
Echinococcus multilocularis lysosomal alpha glucosidase 0.0716 0.1414 0.1414
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0046 0.0053 0.0053
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0018 0.0057
Echinococcus multilocularis peregrin 0.0047 0.0054 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0046 0.0053 0.0187
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0059 0.0079 0.0156
Brugia malayi Pre-SET motif family protein 0.0094 0.0149 0.0441
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0018 0.0057
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.0003 0.0009
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0198 0.121
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0003 0.0004
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0009 0.0012
Brugia malayi Thioredoxin reductase 0.0046 0.0053 0.0157
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0272 0.0511 0.101
Loa Loa (eye worm) hypothetical protein 0.0084 0.0129 0.0456
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0053 0.0053
Echinococcus multilocularis histone acetyltransferase MYST2 0.0175 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Toxoplasma gondii PUL domain-containing protein 0.0041 0.0043 0.0549
Echinococcus granulosus chromobox protein 1 0.0074 0.0109 0.014
Echinococcus granulosus lipoxygenase domain containing protein 0.0147 0.0258 0.0329
Plasmodium vivax vivapain-3 0.0027 0.0013 0.0241
Loa Loa (eye worm) hypothetical protein 0.0085 0.0131 0.0463
Treponema pallidum phosphoglycerate kinase 0.0276 0.0519 0.162
Echinococcus granulosus dna polymerase kappa 0.0296 0.056 0.0715
Onchocerca volvulus 0.0035 0.0029 0.02
Mycobacterium ulcerans aldehyde dehydrogenase 0.0248 0.0464 0.1714
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0064 0.0199
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0101 0.0163 0.0511
Brugia malayi Rhodanese-like domain containing protein 0.012 0.0202 0.0598
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0018 0.0069
Brugia malayi hypothetical protein 0.0022 0.0003 0.0009
Schistosoma mansoni alpha-glucosidase 0.0616 0.1211 0.1547
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0053 0.0068
Echinococcus multilocularis tumor protein p63 0.0372 0.0715 0.0715
Schistosoma mansoni zinc finger protein 0.0026 0.0011 0.0013
Schistosoma mansoni hypothetical protein 0.0085 0.0131 0.0168
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0082 0.0288
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0101 0.0163 0.0163
Echinococcus multilocularis RUN 0.0147 0.0258 0.0258
Plasmodium falciparum endoplasmin, putative 0.0042 0.0043 0.0574
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0041 0.0042 0.0538
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0013 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0079 0.0247
Trichomonas vaginalis cdc25c, putative 0.012 0.0202 0.063
Entamoeba histolytica hypothetical protein 0.0157 0.0277 0.0866
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0018 0.0233
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0029 0.0018 0.0021
Echinococcus granulosus geminin 0.1279 0.2559 0.3268
Loa Loa (eye worm) hypothetical protein 0.0147 0.0258 0.0909
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0254 0.0325
Loa Loa (eye worm) DnaJ domain-containing protein 0.0264 0.0495 0.1746
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0053 0.0157
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0075 0.0112 0.0377
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0053 0.0157
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0018 0.0036
Brugia malayi Bromodomain containing protein 0.0037 0.0034 0.01
Schistosoma mansoni sex comb on midleg homolog 0.0154 0.0272 0.0347
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0018 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0028 0.0015 0.0106
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0149 0.0149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0102 0.0385
Trypanosoma cruzi cysteine peptidase, putative 0.0197 0.0358 0.0708
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0046 0.0053 0.0068
Trypanosoma brucei DNA damage repair protein, putative 0.0083 0.0127 0.0252
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0254 0.0753
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0112 0.0221
Schistosoma mansoni phosphatidylserine receptor 0.0041 0.0042 0.0054
Trichomonas vaginalis heat shock protein, putative 0.0068 0.0097 0.0302
Echinococcus multilocularis polycomb protein SCMH1 0.0154 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0054 0.0069 0.0245
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0093 0.0329
Echinococcus granulosus JmjC domain containing protein 4 0.0041 0.0042 0.0054
Loa Loa (eye worm) transcription factor SMAD2 0.039 0.0751 0.2649
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0013 0.0016
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0075 0.0112 0.1433
Schistosoma mansoni RAR-like nuclear receptor 0.0046 0.0053 0.0068
Echinococcus granulosus microtubule associated protein 2 0.2159 0.4347 0.5552
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Brugia malayi Ets-domain containing protein 0.0072 0.0105 0.0311
Leishmania major hypothetical protein, conserved 0.0041 0.0043 0.0085
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0029 0.009
Loa Loa (eye worm) hypothetical protein 0.0519 0.1013 0.3572
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0046 0.0053 0.0068
Schistosoma mansoni retinoic acid receptor RXR 0.0046 0.0053 0.0068
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0099 0.0126
Leishmania major mitochondrial DNA polymerase beta 0.2509 0.5058 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0081 0.0123 0.0385
Loa Loa (eye worm) doublecortin family protein 0.0147 0.0258 0.0909
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0152
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.005 0.0157
Brugia malayi Phosphoglycerate kinase 0.0101 0.0164 0.0486
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0046 0.0053 0.0068
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0101 0.0163 0.0323
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0059 0.0079 0.0548
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0024 0.0047
Echinococcus granulosus heat shock protein 90 0.0054 0.0069 0.0088
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0028 0.0015 0.0048
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0254 0.0254
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.001 0.0037
Schistosoma mansoni DNA polymerase eta 0.0519 0.1013 0.1294
Leishmania major exosome subunit rrp6p homologue, putative 0.0045 0.005 0.0099
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0021 0.0027
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.012 0.0202 0.063
Brugia malayi PHD-finger family protein 0.0031 0.0021 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.0124
Mycobacterium ulcerans hypothetical protein 0.0045 0.005 0.0142
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0131 0.0131
Trypanosoma cruzi cysteine proteinase, putative 0.0027 0.0013 0.0025
Trypanosoma brucei ribosomal RNA processing protein 6 0.0045 0.005 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0035 0.0149
Echinococcus multilocularis phospholipase A 2 activating protein 0.0041 0.0043 0.0043
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.005 0.0344
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.0013 0.0016
Echinococcus granulosus lysosomal alpha glucosidase 0.0716 0.1414 0.1806
Brugia malayi heat shock protein 90 0.0068 0.0097 0.0286
Trypanosoma brucei DNA polymerase IV, putative 0.0289 0.0546 0.1079
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0003 0.0003
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0029 0.0018 0.0038
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0013 0.004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0296 0.056 0.1107
Loa Loa (eye worm) hypothetical protein 0.0062 0.0084 0.0295
Loa Loa (eye worm) endoplasmin 0.0068 0.0097 0.0341
Schistosoma mansoni hypothetical protein 0.005 0.0059 0.0076
Giardia lamblia PHD finger protein 15 0.0031 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.013 0.0223 0.0785
Brugia malayi ImpB/MucB/SamB family protein 0.0519 0.1013 0.2999
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0012 0.0039
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0779 0.1543 0.5833
Plasmodium vivax endoplasmin, putative 0.0068 0.0097 0.1836
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.003
Echinococcus multilocularis microtubule associated protein 2 0.2159 0.4347 0.4347
Echinococcus granulosus GPCR family 2 0.005 0.0059 0.0076
Toxoplasma gondii heat shock protein 90, putative 0.0068 0.0097 0.1238
Echinococcus multilocularis Polycystic kidney disease protein 0.0147 0.0258 0.0258
Onchocerca volvulus 0.0029 0.0018 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0127 0.0252
Onchocerca volvulus 0.012 0.0202 0.14
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0024 0.0047
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0252 0.0322
Treponema pallidum exodeoxyribonuclease (exoA) 0.0101 0.0163 0.0511
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0174 0.0656
Mycobacterium leprae Probable lipase LipE 0.0038 0.0035 0.0149
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0039 0.0038 0.0048
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.0003 0.0009
Schistosoma mansoni coup transcription factor 0.0046 0.0053 0.0068
Entamoeba histolytica acyl-coA synthetase, putative 0.01 0.0161 0.0504
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0018 0.0064
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0353 0.0676 0.1336
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0237 0.044 0.0869
Echinococcus granulosus cathepsin l1 0.0035 0.0029 0.0037
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1595 0.3201 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.0096 0.0546
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0018 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0035 0.0035
Echinococcus granulosus smad 0.0027 0.0013 0.0016
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0003 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0112 0.0221
Onchocerca volvulus 0.012 0.0202 0.14
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0047 0.0055 0.0192
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0052 0.0064 0.0842
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Giardia lamblia Heat shock protein HSP 90-alpha 0.0068 0.0097 0.0302
Leishmania major DNA polymerase kappa, putative 0.0083 0.0127 0.0252
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0059 0.0079 0.0247
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0064 0.0441
Echinococcus multilocularis importin subunit beta 1 0.003 0.0019 0.0019
Schistosoma mansoni blooms syndrome DNA helicase 0.0117 0.0196 0.0251
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0064 0.0224
Schistosoma mansoni hypothetical protein 0.005 0.0059 0.0076
Onchocerca volvulus 0.0052 0.0064 0.0441
Plasmodium vivax heat shock protein 90, putative 0.0028 0.0015 0.0289
Echinococcus granulosus chromobox protein 1 0.0074 0.0109 0.014
Schistosoma mansoni hypothetical protein 0.0021 0.0002 0.0002
Brugia malayi Heterochromatin protein 1 0.0074 0.0109 0.0324
Brugia malayi conserved hypotetical protein 0.0022 0.0003 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Schistosoma mansoni hypothetical protein 0.0031 0.0021 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.013 0.0223 0.044
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0175 0.0315 0.0934
Toxoplasma gondii Hsp90 domain-containing protein 0.0028 0.0015 0.0195
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0053 0.1004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0229 0.0425 0.544
Trypanosoma cruzi cysteine peptidase, putative 0.0197 0.0358 0.0708
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.012 0.0202 0.063
Leishmania major cathepsin L-like protease 0.0052 0.0064 0.0126
Trypanosoma cruzi DNA polymerase kappa, putative 0.0296 0.056 0.1107
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0268 0.0503 0.0503
Trichomonas vaginalis rotamase, putative 0.0032 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0064
Trichomonas vaginalis maltase-glucoamylase, putative 0.0159 0.0282 0.0879
Loa Loa (eye worm) hypothetical protein 0.025 0.0466 0.1644
Leishmania major cysteine peptidase A (CPA) 0.0052 0.0064 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0296 0.056 0.175
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0154 0.0272 0.1887
Brugia malayi AMP-binding enzyme family protein 0.01 0.0161 0.0478
Onchocerca volvulus 0.0106 0.0173 0.1204
Echinococcus multilocularis cysteine protease 0.0052 0.0064 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Schistosoma mansoni ferritin light chain 0.0027 0.0013 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Schistosoma mansoni lipoxygenase 0.0213 0.0391 0.0499
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Echinococcus multilocularis cathepsin L cysteine protease 0.0052 0.0064 0.0064
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0018 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Plasmodium vivax JmjC domain containing protein 0.0041 0.0042 0.0798
Echinococcus granulosus cathepsin L cysteine proteinase 0.0052 0.0064 0.0081
Trichomonas vaginalis maltase-glucoamylase, putative 0.0059 0.0079 0.0247
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0101 0.0163 0.0323
Loa Loa (eye worm) hypothetical protein 0.0039 0.0039 0.0136
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0069 0.0214
Giardia lamblia Fructose-bisphosphate aldolase 0.1595 0.3201 1
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0013 0.0025
Plasmodium vivax SET domain protein, putative 0.0094 0.0149 0.2826
Brugia malayi RNA binding protein 0.0066 0.0093 0.0276
Brugia malayi Importin beta-1 subunit 0.003 0.0019 0.0056
Echinococcus granulosus cathepsin l cysteine peptidase 0.0052 0.0064 0.0081
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0018 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0042 0.0148
Onchocerca volvulus 0.012 0.0202 0.14
Brugia malayi Bromodomain containing protein 0.0043 0.0046 0.0136
Trypanosoma cruzi DNA damage repair protein, putative 0.0083 0.0127 0.0252
Trypanosoma cruzi DNA polymerase eta, putative 0.0334 0.0638 0.1261
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0198 0.0747
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0102 0.0385
Echinococcus granulosus intestinal type alkaline phosphatase 0.3872 0.783 1
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0266 0.0787
Onchocerca volvulus 0.0046 0.0053 0.0368
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.01 0.0161 0.0565
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0114 0.1465
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0053 0.02
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0052 0.0164
Toxoplasma gondii hypothetical protein 0.0405 0.0781 1
Onchocerca volvulus 0.0414 0.08 0.5553
Loa Loa (eye worm) MBCTL1 0.0175 0.0315 0.1112
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0047 0.0055 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0046 0.0053 0.0187
Schistosoma mansoni hypothetical protein 0.005 0.0061 0.0078
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0028 0.0015 0.0015
Schistosoma mansoni bromodomain containing protein 0.007 0.0102 0.013
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0279 0.0527 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0117 0.0196 0.2513
Mycobacterium ulcerans lipase LipD 0.0038 0.0035 0.0085
Trypanosoma brucei phosphoglycerate kinase 0.0101 0.0164 0.0325
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0018 0.0069
Loa Loa (eye worm) fibroinase 0.0052 0.0064 0.0224
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0021 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0093 0.0119
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0024 0.0303
Plasmodium falciparum ataxin-2 like protein, putative 0.013 0.0223 0.2948
Brugia malayi Smad1 0.0027 0.0013 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0046 0.0053 0.0157
Schistosoma mansoni blooms syndrome DNA helicase 0.0317 0.0604 0.0771
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0111 0.0184 0.0184
Echinococcus granulosus importin subunit beta 1 0.003 0.0019 0.0024
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Leishmania major cathepsin L-like protease 0.0052 0.0064 0.0126
Entamoeba histolytica recQ family helicase, putative 0.0112 0.0187 0.0585
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0229 0.0425 0.544
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0138 0.0176
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0334 0.0638 0.8166
Schistosoma mansoni jumonji/arid domain-containing protein 0.0158 0.0279 0.0356
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0149 0.019
Loa Loa (eye worm) MH2 domain-containing protein 0.039 0.0751 0.2649
Trypanosoma brucei heat shock protein 84, putative 0.0028 0.0015 0.003
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0029 0.0018 0.0021
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0248 0.0464 0.0464
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0035 0.0124
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0043 0.0299
Brugia malayi steroid hormone receptor 0.0046 0.0053 0.0157
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.201
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0053 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0035 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0053 0.0157
Trypanosoma brucei DNA polymerase eta, putative 0.0519 0.1013 0.2003
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.0003 0.0004
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0012 0.0163
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0003 0.0009
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.01 0.0161 0.0565
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0019 0.0066
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.06 0.2117
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0237 0.044 0.844
Echinococcus multilocularis GPCR, family 2 0.005 0.0059 0.0059
Mycobacterium leprae conserved hypothetical protein 0.0045 0.005 0.0247
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0101 0.0164 0.0325
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0353 0.0676 0.1336
Loa Loa (eye worm) hypothetical protein 0.0117 0.0196 0.0692
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0046 0.0053 0.0068
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0003 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0052 0.0064 0.0199
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0018 0.0069
Schistosoma mansoni phd/f-box containing protein 0.0041 0.0042 0.0054
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0174 0.0656
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Echinococcus multilocularis alkaline phosphatase 0.3872 0.783 0.783
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0024 0.0074
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0097 0.0191
Schistosoma mansoni ferritin light chain 0.0027 0.0013 0.0016
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0019 0.024
Giardia lamblia DINP protein human, muc B family 0.0275 0.0517 0.1615
Entamoeba histolytica phosphoglycerate kinase, putative 0.0276 0.0519 0.162
Brugia malayi hypothetical protein 0.0147 0.0258 0.0763
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0392 0.0755 1
Onchocerca volvulus Alhambra homolog 0.0031 0.0021 0.0148
Echinococcus multilocularis phosphoglycerate kinase 1 0.0276 0.0519 0.0519
Echinococcus granulosus Helicase RNase D C terminal HRDC domain 0.0045 0.005 0.0064
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0029 0.0018 0.0021
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Brugia malayi Bloom's syndrome protein homolog 0.0434 0.0841 0.2491
Mycobacterium tuberculosis Conserved hypothetical alanine rich protein 0.0045 0.005 0.019
Trypanosoma brucei heat shock protein 90, putative 0.0068 0.0097 0.0191
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0052 0.0995
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0035 0.0045
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0052 0.0064 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0237 0.044 0.1663
Trichomonas vaginalis inositol monophosphatase, putative 0.0075 0.0112 0.035
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0046 0.0053 0.0187
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0237 0.044 0.0869
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Echinococcus multilocularis neuropeptide receptor A26 0.0945 0.188 0.188
Trypanosoma brucei DNA polymerase kappa, putative 0.0192 0.0348 0.0688
Echinococcus granulosus m phase inducer phosphatasecdc25 0.012 0.0202 0.0258
Brugia malayi Fli-1 protein 0.0219 0.0403 0.1193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0254 0.0325
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0154 0.0272 0.0347
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0053 0.0105
Schistosoma mansoni heat shock protein 0.0068 0.0097 0.0123
Entamoeba histolytica cysteine proteinase 1, putative 0.0027 0.0013 0.004
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0099 0.0373
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0029 0.0018 0.0038
Leishmania major phosphoglycerate kinase B, cytosolic 0.0276 0.0519 0.1026
Brugia malayi nuclear receptor RXR 0.0022 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0157 0.0277 0.0977
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.004 0.0531
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0079 0.0247
Echinococcus multilocularis snurportin 1 0.0316 0.06 0.06
Plasmodium vivax multidomain scavenger receptor, putative 0.0147 0.0258 0.4893
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Schistosoma mansoni leucine aminopeptidase 0.0047 0.0055 0.007
Echinococcus multilocularis Helicase RNase D C terminal, HRDC domain 0.0045 0.005 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0003 0.0022
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0779 0.1543 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0054
Schistosoma mansoni thyroid hormone receptor 0.0046 0.0053 0.0068
Trypanosoma cruzi DNA polymerase kappa, putative 0.0296 0.056 0.1107
Onchocerca volvulus 0.0052 0.0064 0.0441
Trypanosoma brucei unspecified product 0.0289 0.0546 0.1079
Brugia malayi cathepsin L-like precursor 0.0035 0.0029 0.0086
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0059 0.0059
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0059 0.0079 0.0247
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0059 0.0079 0.0156
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.0148
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0275 0.0517 0.1954
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0104 0.0133
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0009 0.0009
Schistosoma mansoni sex comb on midleg homolog 0.0154 0.0272 0.0347
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0389
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0389
Brugia malayi Bromodomain containing protein 0.0082 0.0126 0.0373
Loa Loa (eye worm) hypothetical protein 0.005 0.0059 0.021
Schistosoma mansoni myelin transcription factor 1 myt1 0.0175 0.0315 0.0403
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.003
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0101 0.0163 0.0576
Trichomonas vaginalis DNA helicase recq, putative 0.0272 0.0511 0.1596
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0248 0.0464 0.0917
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0053 0.0068
Onchocerca volvulus 0.0029 0.0018 0.0126
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Toxoplasma gondii aldehyde dehydrogenase 0.0248 0.0464 0.5937
Brugia malayi Cathepsin L-like precursor 0.0035 0.0029 0.0086
Loa Loa (eye worm) hypothetical protein 0.1415 0.2836 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0059 0.021
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0105 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0035 0.011
Brugia malayi jmjC domain containing protein 0.0041 0.0042 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Onchocerca volvulus 0.0038 0.0035 0.0244
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0716 0.1414 0.4986
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0386
Onchocerca volvulus 0.0147 0.0258 0.1788
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0004 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0018 0.0233
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0146
Schistosoma mansoni alpha glucosidase 0.0159 0.0282 0.036
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0389
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0058 0.0077 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0018 0.0058
Trypanosoma brucei glycosyl hydrolase-like protein 0.0059 0.0079 0.0156
Leishmania major cathepsin L-like protease 0.0052 0.0064 0.0126
Echinococcus multilocularis zinc finger protein 0.0026 0.0011 0.0011
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0013 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.0158 0.0279 0.0356
Plasmodium vivax unspecified product 0.0027 0.0013 0.0241
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0131 0.0168
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0275 0.0517 0.1022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0248 0.0464 0.1714
Brugia malayi nuclear receptor NHR-88 0.0046 0.0053 0.0157
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0021 0.0027
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0628 0.1235 0.1577
Schistosoma mansoni polymyositis/scleroderma autoantigen-related 0.0045 0.005 0.0064
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0035 0.0133
Loa Loa (eye worm) glutaminase 2 0.0278 0.0524 0.1848
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0018 0.0345
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0046 0.0053 0.0157
Loa Loa (eye worm) hypothetical protein 0.0033 0.0025 0.0088
Echinococcus multilocularis smad 0.0027 0.0013 0.0013
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.0003 0.0004
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0266 0.0339
Chlamydia trachomatis phosphoglycerate kinase 0.0276 0.0519 1
Echinococcus granulosus RUN 0.0147 0.0258 0.0329
Leishmania major DNA polymerase eta, putative 0.0334 0.0638 0.1261
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0013 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Schistosoma mansoni hypothetical protein 0.0085 0.0131 0.0168
Plasmodium vivax vivapain-2 0.0052 0.0064 0.1207
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0012 0.0234
Plasmodium vivax phosphoglycerate kinase, putative 0.0276 0.0519 0.985
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0254 0.0897
Plasmodium falciparum JmjC domain-containing protein, putative 0.0041 0.0042 0.0556
Echinococcus granulosus snurportin 1 0.0316 0.06 0.0767
Mycobacterium ulcerans ATP-dependent DNA helicase II UvrD2 0.0042 0.0045 0.0122
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0035 0.0104
Loa Loa (eye worm) hypothetical protein 0.0229 0.0425 0.1499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Brugia malayi PHD-finger family protein 0.0031 0.0022 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0035 0.011
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0175 0.0315 0.0403
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0046 0.0053 0.0053
Schistosoma mansoni endoplasmin 0.0068 0.0097 0.0123
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0176 0.0522
Schistosoma mansoni apoferritin-2 0.0027 0.0013 0.0016
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0094 0.0094
Brugia malayi ecdysteroid receptor 0.0046 0.0053 0.0157
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0046 0.0053 0.0068
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.01 0.0161 0.0974
Onchocerca volvulus 0.0052 0.0064 0.0441
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0083 0.0127 0.1632
Loa Loa (eye worm) hypothetical protein 0.0107 0.0176 0.0622
Brugia malayi Pre-SET motif family protein 0.0641 0.1262 0.3736
Schistosoma mansoni smad 0.0027 0.0013 0.0016
Brugia malayi 3'-5' exonuclease family protein 0.0045 0.005 0.0149
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.012 0.0202 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0112 0.0221
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0028 0.0015 0.0019
Loa Loa (eye worm) mbt repeat family protein 0.0154 0.0272 0.0959
Echinococcus multilocularis cysteine protease 0.0052 0.0064 0.0064
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0002 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0254 0.0325
Echinococcus multilocularis chromobox protein 1 0.0074 0.0109 0.0109
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0276 0.0519 0.6641
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0093 0.0276
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0105
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0018 0.0069
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0018 0.0018
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0018 0.0036
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0047 0.0055 0.0192
Echinococcus granulosus lysine specific demethylase 6a 0.0041 0.0042 0.0054
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0102
Brugia malayi Cathepsin L-like precursor 0.0052 0.0064 0.0188
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0024 0.0008 0.0016
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0015 0.0201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0029 0.009
Plasmodium vivax vivapain-1 0.0027 0.0013 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0045 0.014
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0018 0.0036
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0035 0.0133
Trichomonas vaginalis alpha-glucosidase, putative 0.0159 0.0282 0.0879
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0101 0.0163 0.2979
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.0124
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0018 0.0023
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.2509 0.5058 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0154 0.0271 0.0271
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0034 0.0043
Echinococcus multilocularis geminin 0.1279 0.2559 0.2559
Schistosoma mansoni smad1 5 8 and 0.0027 0.0013 0.0016
Echinococcus multilocularis leucyl aminopeptidase 0.0047 0.0055 0.0055
Entamoeba histolytica rodhanase-like domain containing protein 0.012 0.0202 0.063
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0092 0.0146 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0175 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0276 0.0519 0.1829
Trypanosoma cruzi cruzipain precursor, putative 0.0197 0.0358 0.0708
Toxoplasma gondii leucyl aminopeptidase LAP 0.0237 0.044 0.563
Schistosoma mansoni survival motor neuron protein 0.005 0.0061 0.0078
Onchocerca volvulus 0.0022 0.0003 0.0022
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0101 0.0164 0.0325
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0069 0.0214
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0277 0.0821
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0131 0.0131
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0088 0.031
Echinococcus granulosus peregrin 0.0047 0.0054 0.0069
Leishmania major DNA polymerase eta, putative 0.0519 0.1013 0.2003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0277 0.0977
Onchocerca volvulus 0.0092 0.0146 0.1016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0101 0.0163 0.3104
Onchocerca volvulus 0.0032 0.0023 0.016
Brugia malayi exodeoxyribonuclease III family protein 0.0101 0.0163 0.0484
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0161 0.0565
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0035 0.011
Brugia malayi GnHR receptor homolog 0.1682 0.3377 1
Plasmodium falciparum phosphoglycerate kinase 0.0276 0.0519 0.6868
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0114
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0059 0.0079 0.0247
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0035 0.0133
Giardia lamblia Grp94/Hsp90 0.0054 0.0069 0.0214
Treponema pallidum fructose-bisphosphate aldolase 0.1595 0.3201 1
Trypanosoma brucei heat shock protein 90, putative 0.0068 0.0097 0.0191
Entamoeba histolytica heat shock protein 90, putative 0.0068 0.0097 0.0302
Trichomonas vaginalis chromobox protein, putative 0.0045 0.005 0.0155
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.012 0.0202 0.0712
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0003 0.0022
Brugia malayi MH1 domain containing protein 0.0027 0.0013 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0159 0.0282 0.0879
Echinococcus multilocularis cathepsin L 0.0027 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0106 0.0173 0.0222
Mycobacterium tuberculosis Conserved protein 0.0038 0.0035 0.0133
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0102 0.0385
Schistosoma mansoni ap endonuclease 0.0101 0.0163 0.0209
Schistosoma mansoni zinc finger protein 0.0022 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.0148
Plasmodium falciparum cysteine proteinase falcipain 3 0.0052 0.0064 0.0842
Loa Loa (eye worm) heat shock protein 75 0.0028 0.0015 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0192 0.0348 0.0688
Trypanosoma cruzi heat shock protein 90, putative 0.0054 0.0069 0.0136
Echinococcus granulosus cpg binding protein 0.0035 0.0031 0.0039
Onchocerca volvulus 0.012 0.0202 0.14
Loa Loa (eye worm) hypothetical protein 0.011 0.0183 0.0645
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0064 0.0199
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0229 0.0425 0.0543
Schistosoma mansoni thyroid hormone receptor 0.0046 0.0053 0.0068
Plasmodium vivax importin-beta 2, putative 0.003 0.0019 0.0356
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0109 0.0342
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0248 0.0464 0.0592
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.012 0.0202 0.0202
Echinococcus multilocularis phd:f box containing protein 0.0041 0.0042 0.0042
Schistosoma mansoni chromobox protein 0.0074 0.0109 0.014
Brugia malayi mbt repeat family protein 0.0154 0.0272 0.0805
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0035 0.011
Leishmania major cathepsin L-like protease 0.0052 0.0064 0.0126
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0046 0.0053 0.0368
Schistosoma mansoni DNA helicase recq1 0.0229 0.0425 0.0543
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0046 0.0053 0.0068
Echinococcus granulosus expressed protein 0.0033 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.0003 0.0011
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0101 0.0163 0.0323
Schistosoma mansoni ap endonuclease 0.0101 0.0163 0.0209
Mycobacterium ulcerans glutaminase 0.0278 0.0524 0.1942
Leishmania major hypothetical protein, conserved 0.013 0.0223 0.044
Echinococcus granulosus dna polymerase eta 0.0519 0.1013 0.1294
Brugia malayi DnaJ domain containing protein 0.0264 0.0495 0.1466
Schistosoma mansoni heat shock protein 0.0028 0.0015 0.0019
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0217 0.0401 0.0512
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Loa Loa (eye worm) oxidoreductase 0.0029 0.0018 0.0064
Mycobacterium tuberculosis Conserved hypothetical protein 0.1321 0.2645 1
Brugia malayi glutaminase DH11.1 0.0278 0.0524 0.1551
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.0003 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0159 0.0282 0.0557
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0159 0.0282 0.0557
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0075 0.0112 0.035
Schistosoma mansoni endoplasmin 0.0068 0.0097 0.0123
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0018 0.0069
Loa Loa (eye worm) glutaminase 0.0278 0.0524 0.1848
Brugia malayi Cathepsin L-like precursor 0.0052 0.0064 0.0188
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0046 0.0053 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0135
Echinococcus granulosus Polycystic kidney disease protein 0.0147 0.0258 0.0329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Trichomonas vaginalis cdc25b, putative 0.012 0.0202 0.063
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0019 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0046 0.0053 0.0187
Echinococcus granulosus tar DNA binding protein 0.0066 0.0093 0.0119
Trichomonas vaginalis ap endonuclease, putative 0.0101 0.0163 0.0511
Trichomonas vaginalis alpha-glucosidase, putative 0.0159 0.0282 0.0879
Loa Loa (eye worm) hypothetical protein 0.0059 0.0079 0.0278
Plasmodium falciparum phd finger protein, putative 0.0031 0.0021 0.0282
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Schistosoma mansoni smad1 5 8 and 0.0027 0.0013 0.0016
Echinococcus granulosus jumonji domain containing 1A 0.0041 0.0042 0.0054
Echinococcus multilocularis chromobox protein 1 0.0074 0.0109 0.0109
Echinococcus granulosus zinc finger protein 0.0026 0.0011 0.0013
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0131 0.0168
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0099 0.0292
Trypanosoma cruzi PAB1-binding protein , putative 0.013 0.0223 0.044
Leishmania major pantothenate kinase subunit, putative 0.0024 0.0008 0.0016
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0018 0.0036
Schistosoma mansoni hypothetical protein 0.1279 0.2559 0.3268
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0018 0.0064
Trypanosoma brucei DNA polymerase IV, putative 0.0296 0.056 0.1107
Loa Loa (eye worm) acetyltransferase 0.0151 0.0266 0.0937
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0161 0.0565
Brugia malayi Cathepsin L-like precursor 0.0052 0.0064 0.0188
Leishmania major cathepsin L-like protease 0.0197 0.0358 0.0708
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0013 0.0016
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0097 0.0191
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0054 0.0069 0.0088
Brugia malayi Steroid receptor seven-up type 2 0.0046 0.0053 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0061 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0197 0.0358 0.0708
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0272 0.0511 0.101
Brugia malayi AMP-binding enzyme family protein 0.01 0.0161 0.0478
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0268 0.0503 0.0642
Leishmania major 4-coumarate:coa ligase-like protein 0.01 0.0161 0.0319
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0058 0.0077 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Echinococcus granulosus phosphoglycerate kinase 1 0.0276 0.0519 0.0662
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0013 0.0016
Leishmania major trypanothione reductase 0.0046 0.0053 0.0105
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0099 0.0195
Echinococcus multilocularis heat shock protein 90 0.0068 0.0097 0.0097
Schistosoma mansoni heat shock protein 0.0068 0.0097 0.0123
Loa Loa (eye worm) ctsf protein 0.0052 0.0064 0.0224
Entamoeba histolytica hypothetical protein 0.0024 0.0007 0.0023
Entamoeba histolytica recQ family helicase, putative 0.0272 0.0511 0.1596
Schistosoma mansoni inositol monophosphatase 0.0075 0.0112 0.0143
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0131 0.0168
Brugia malayi AMP-binding enzyme family protein 0.01 0.0161 0.0478
Mycobacterium ulcerans fatty-acid-CoA ligase 0.01 0.0161 0.0565
Plasmodium vivax DNA repair protein REV1, putative 0.0083 0.0127 0.2421
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.012 0.0202 0.063
Loa Loa (eye worm) hypothetical protein 0.01 0.0161 0.0569
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1595 0.3201 1
Brugia malayi Doublecortin family protein 0.0147 0.0258 0.0763
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0041 0.0043 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Echinococcus multilocularis endoplasmin 0.0054 0.0069 0.0069
Brugia malayi Cathepsin L-like precursor 0.0035 0.0029 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0185 0.0366
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0034 0.0034
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0628 0.1235 0.1235
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.3872 0.783 0.783
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0093 0.0329
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0035 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0083 0.0127 0.0252
Echinococcus multilocularis heat shock protein 0.0068 0.0097 0.0097
Brugia malayi nuclear receptor NHR-67 0.0022 0.0003 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.0147 0.0258 0.0258
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0009 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0254 0.0325
Treponema pallidum heat shock protein 90 0.0054 0.0069 0.0214
Brugia malayi Glycosyl hydrolases family 31 protein 0.0716 0.1414 0.4186
Brugia malayi Glycosyl hydrolases family 31 protein 0.0059 0.0079 0.0234
Echinococcus multilocularis leucyl aminopeptidase 0.0047 0.0055 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0053 0.0157
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0389
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0052 0.0064 0.0842
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Loa Loa (eye worm) hypothetical protein 0.0081 0.0123 0.0434
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0059 0.0059
Schistosoma mansoni inositol monophosphatase 0.0075 0.0112 0.0143
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0237 0.044 0.0869
Brugia malayi hypothetical protein 0.0084 0.0129 0.0382
Schistosoma mansoni lipoxygenase 0.0477 0.0929 0.1187
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0035 0.0069
Schistosoma mansoni rab6-interacting 0.0147 0.0258 0.0329
Loa Loa (eye worm) jmjC domain-containing protein 0.0158 0.0279 0.0984
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0046 0.0053 0.0187
Plasmodium falciparum glutathione reductase 0.0046 0.0053 0.07
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Trypanosoma cruzi cysteine protease, putative 0.0027 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0077 0.0114 0.0404
Entamoeba histolytica cysteine protease, putative 0.0052 0.0064 0.0199
Plasmodium falciparum LCCL domain-containing protein 0.0147 0.0258 0.3412
Trypanosoma cruzi ribosomal RNA processing protein 6, putative 0.0045 0.005 0.0099
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0019 0.0037
Brugia malayi Trypsin family protein 0.0092 0.0146 0.0434
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0035 0.0667
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.1187 0.2372 0.469
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0229 0.0425 0.0543
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0035 0.0045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.01 0.0161 0.0974
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0018 0.0038
Leishmania major glycosyl hydrolase-like protein 0.0059 0.0079 0.0156
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.0105
Trypanosoma brucei unspecified product 0.0185 0.0334 0.066
Brugia malayi beta-lactamase family protein 0.0038 0.0035 0.0104
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0102
Trypanosoma brucei aminopeptidase, putative 0.0047 0.0055 0.0108
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0064 0.0441
Brugia malayi jmjC domain containing protein 0.0217 0.0401 0.1186
Echinococcus multilocularis heat shock protein 90 0.0054 0.0069 0.0069
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0157 0.0277 0.0354
Loa Loa (eye worm) hypothetical protein 0.0147 0.0258 0.0909
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0049 0.0059 0.0207
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Plasmodium falciparum cysteine proteinase falcipain 1 0.0027 0.0013 0.0168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0117 0.0196 0.0388
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0097 0.0191
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.1187 0.2372 0.469
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0198 0.0747
Echinococcus granulosus endoplasmin 0.0054 0.0069 0.0088
Brugia malayi ImpB/MucB/SamB family protein 0.0268 0.0503 0.1488
Leishmania major hypothetical protein, conserved 0.0041 0.0042 0.0083
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0009 0.0025
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0183 0.0645
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0035 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0046 0.0053 0.0157
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.009 0.0142 0.1815
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0061 0.0181
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0003 0.0004
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0276 0.0519 0.3309
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0035 0.0133
Plasmodium falciparum M17 leucyl aminopeptidase 0.0237 0.044 0.5823
Schistosoma mansoni hypothetical protein 0.2012 0.4049 0.5171
Brugia malayi hypothetical protein 0.0022 0.0003 0.0009
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0047 0.0055 0.007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0101 0.0163 0.2164
Onchocerca volvulus 0.0029 0.0018 0.0126
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0069 0.0089
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0043 0.0135
Schistosoma mansoni phosphoglycerate kinase 0.0276 0.0519 0.0662
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0101 0.0164 0.0325
Brugia malayi MH2 domain containing protein 0.0027 0.0013 0.0037
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0012 0.0035
Trypanosoma cruzi Heat shock protein 83, putative 0.0068 0.0097 0.0191
Schistosoma mansoni ferritin 0.0027 0.0013 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.0461 0.0461
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0035 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0159 0.0282 0.0879
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0159 0.0282 0.0879
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0248 0.0464 0.1754
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0075 0.0112 0.0221
Schistosoma mansoni hypothetical protein 0.005 0.0059 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0064 0.0199
Schistosoma mansoni cathepsin F (C01 family) 0.0052 0.0064 0.0081
Schistosoma mansoni steroid hormone receptor ad4bp 0.0046 0.0053 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Entamoeba histolytica recQ family DNA helicase 0.0117 0.0196 0.0613
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0114 0.0667
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.3872 0.783 0.783
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0009 0.003
Trypanosoma brucei phosphoglycerate kinase, putative 0.0101 0.0164 0.0325
Loa Loa (eye worm) RecQ helicase 0.0434 0.0841 0.2967
Trichomonas vaginalis alpha-glucosidase, putative 0.0159 0.0282 0.0879
Schistosoma mansoni hypothetical protein 0.0085 0.0131 0.0168
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0025 0.0075
Schistosoma mansoni glutaminase 0.0278 0.0524 0.0669
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.0013 0.0016
Echinococcus granulosus cathepsin L 0.0027 0.0013 0.0016
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0268 0.0503 0.1772
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0075 0.0112 0.1961
Trypanosoma brucei DNA polymerase IV, putative 0.0296 0.056 0.1107
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0237 0.044 0.8351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0102 0.0385
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0229 0.0425 0.5627
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0046 0.0053 0.0157
Echinococcus granulosus FTZ F1 alpha 0.0046 0.0053 0.0068
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0075 0.011 0.037
Toxoplasma gondii thioredoxin reductase 0.0046 0.0053 0.0677
Mycobacterium ulcerans heat shock protein 90 0.0054 0.0069 0.0212
Echinococcus granulosus tumor protein p63 0.0372 0.0715 0.0913
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0159 0.0282 0.3604
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0174 0.0656
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0059 0.0076
Echinococcus granulosus inositol monophosphatase 1 0.0075 0.0112 0.0143
Brugia malayi ecdysone receptor 0.0022 0.0003 0.0009
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0018 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.013 0.0223 0.2948
Loa Loa (eye worm) glutathione reductase 0.0046 0.0053 0.0186
Echinococcus multilocularis bloom syndrome protein 0.0434 0.0841 0.0841
Schistosoma mansoni ferritin 0.0027 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.0124
Brugia malayi Ets-domain containing protein 0.0072 0.0105 0.0311
Trypanosoma brucei DNA damage repair protein, putative 0.0083 0.0127 0.0252
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0021 0.0272
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0054 0.0069 0.0259
Schistosoma mansoni hypothetical protein 0.0107 0.0176 0.0225
Schistosoma mansoni alkaline phosphatase 0.3872 0.783 1
Trypanosoma brucei hypothetical protein, conserved 0.0083 0.0127 0.0252
Trichomonas vaginalis chromobox protein, putative 0.0045 0.005 0.0155
Mycobacterium ulcerans DNA polymerase IV 0.0296 0.056 0.208
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0093 0.0119
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0018 0.0069
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0052 0.0064 0.0064
Brugia malayi hypothetical protein 0.0247 0.0461 0.1364
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0045 0.005 0.0063
Echinococcus multilocularis dna polymerase eta 0.0519 0.1013 0.1013
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0013 0.0038
Brugia malayi polk-prov protein 0.0111 0.0185 0.0548
Echinococcus granulosus lysine specific demethylase 5A 0.0158 0.0279 0.0356
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0013 0.0013
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0064 0.0188
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0114 0.2174
Brugia malayi RNA, U transporter 1 0.0084 0.013 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0135
Entamoeba histolytica cysteine protease, putative 0.0027 0.0013 0.004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0147 0.0258 0.0258
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.0069 0.0136
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0198 0.0747
Echinococcus granulosus Smad4 0.0027 0.0013 0.0016
Onchocerca volvulus 0.0038 0.0035 0.0244
Giardia lamblia Sgs1 DNA helicase, putative 0.0229 0.0425 0.1327
Entamoeba histolytica hypothetical protein 0.0157 0.0277 0.0866
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0046 0.0046
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0041 0.0042 0.0083
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0101 0.0164 0.0325
Trypanosoma brucei phosphoglycerate kinase 0.0276 0.0519 0.1026
Plasmodium vivax heat shock protein 86, putative 0.0068 0.0097 0.1836
Plasmodium vivax heat shock protein, putative 0.0028 0.0015 0.0289
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0477 0.0929 0.1187
Trichomonas vaginalis cdc25b, putative 0.012 0.0202 0.063
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0013 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0021 0.0272
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1595 0.3201 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0161 0.0569
Entamoeba histolytica acyl-CoA synthetase, putative 0.01 0.0161 0.0504
Trichomonas vaginalis protein kinase inhibitor, putative 0.0264 0.0495 0.1546
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0114 0.1516
Trypanosoma brucei heat shock protein, putative 0.0068 0.0097 0.0191
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.01 0.0161 0.061
Mycobacterium ulcerans hypothetical protein 0.1321 0.2645 1
Echinococcus granulosus phd:f box containing protein 0.0041 0.0042 0.0054
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.0124
Schistosoma mansoni hypothetical protein 0.0058 0.0077 0.0098
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0157 0.0277 0.0277
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0079 0.0247
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0282 0.0993
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0276 0.0519 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0117 0.0196 0.0388
Loa Loa (eye worm) hypothetical protein 0.0247 0.0461 0.1625
Schistosoma mansoni alkaline phosphatase 0.3872 0.783 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0114 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0197 0.0358 0.0708
Toxoplasma gondii cathepsin CPL 0.0052 0.0064 0.0814
Echinococcus granulosus polycomb protein SCMH1 0.0154 0.0272 0.0347
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0046 0.0053 0.0053
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0041 0.0042 0.0054
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0075 0.0112 0.035
Trypanosoma brucei DNA polymerase kappa, putative 0.0296 0.056 0.1107
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Mycobacterium ulcerans DNA polymerase IV 0.0296 0.056 0.208
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0018 0.0069
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Brugia malayi jmjC domain containing protein 0.0158 0.0279 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0046 0.0053 0.0157
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0046 0.0053 0.0053
Schistosoma mansoni loxhd1 0.0147 0.0258 0.0329
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0061 0.023
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0052 0.0067
Brugia malayi nuclear hormone receptor 0.0022 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0316 0.06 0.0767
Mycobacterium tuberculosis Probable reductase 0.0106 0.0174 0.0656
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0275 0.0518 0.6626
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0007 0.0015
Schistosoma mansoni rotamase 0.0033 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.01 0.0161 0.0569
Trypanosoma brucei DNA polymerase kappa, putative 0.0275 0.0517 0.1022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0053 0.0068
Trypanosoma brucei mitochondrial DNA polymerase beta 0.2509 0.5058 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0052 0.0064 0.0064
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0101 0.0163 0.0323
Schistosoma mansoni hypothetical protein 0.005 0.0059 0.0076
Echinococcus granulosus bloom syndrome protein 0.0434 0.0841 0.1074
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0054 0.0069 0.0368
Leishmania major DNA polymerase kappa, putative 0.0275 0.0517 0.1022
Echinococcus multilocularis ferritin 0.0027 0.0013 0.0013
Onchocerca volvulus Huntingtin homolog 0.025 0.0466 0.3234
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.2509 0.5058 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0054 0.0069 0.1104
Onchocerca volvulus 0.0729 0.1441 1
Schistosoma mansoni aldehyde dehydrogenase 0.0248 0.0464 0.0592
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.0013 0.0016
Loa Loa (eye worm) cysteine protease 0.0052 0.0064 0.0224
Echinococcus granulosus alkaline phosphatase 0.3872 0.783 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0477 0.0929 0.0929
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0018 0.0241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0053 0.0053
Trypanosoma cruzi cysteine proteinase, putative 0.0027 0.0013 0.0025
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0035 0.0133
Echinococcus granulosus dnaJ subfamily C 6 0.0264 0.0495 0.0632
Trichomonas vaginalis alpha-glucosidase, putative 0.0159 0.0282 0.0879
Entamoeba histolytica deoxycytidyl transferase, putative 0.0268 0.0503 0.157
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.01 0.0161 0.0565
Mycobacterium ulcerans hypothetical protein 0.01 0.0161 0.0565
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0015 0.0201
Schistosoma mansoni terminal deoxycytidyl transferase 0.0268 0.0503 0.0642
Echinococcus granulosus histone lysine methyltransferase setb 0.0111 0.0184 0.0235
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0229 0.0425 0.1258
Loa Loa (eye worm) hypothetical protein 0.0073 0.0106 0.0374
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0003 0.0004
Schistosoma mansoni alpha-glucosidase 0.0616 0.1211 0.1547
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0093 0.0093
Trichomonas vaginalis glutaminase, putative 0.0278 0.0524 0.1637
Brugia malayi cytosol aminopeptidase 0.0047 0.0055 0.0161
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0009 0.0011
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0099 0.0099
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0254 0.0254
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.004 0.0125
Onchocerca volvulus 0.0154 0.0272 0.1887
Echinococcus granulosus SAM and MBT domain containing protein 0.0154 0.0272 0.0347
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0013 0.004
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0046 0.0058
Echinococcus multilocularis cpg binding protein 0.0035 0.0031 0.0031
Brugia malayi CXXC zinc finger family protein 0.0032 0.0023 0.0068
Loa Loa (eye worm) inositol-1 0.0075 0.0112 0.0395
Schistosoma mansoni jumonji domain containing protein 0.0197 0.0358 0.0458
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0131 0.0463
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0046 0.0053 0.0068
Schistosoma mansoni cpg binding protein 0.0035 0.0031 0.0039
Leishmania major cathepsin L-like protease 0.0052 0.0064 0.0126
Brugia malayi MH2 domain containing protein 0.039 0.0751 0.2224
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0047 0.0055 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0192 0.0348 0.0688
Trypanosoma cruzi DNA polymerase eta, putative 0.0519 0.1013 0.2003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.0224
Echinococcus granulosus neuropeptide s receptor 0.0945 0.188 0.2401
Trypanosoma brucei unspecified product 0.0185 0.0334 0.066
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0009 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0111 0.0184 0.0235
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0353 0.0676 0.1336
Entamoeba histolytica hypothetical protein 0.0157 0.0277 0.0866
Onchocerca volvulus 0.0022 0.0003 0.0022
Loa Loa (eye worm) fli-1 protein 0.0219 0.0403 0.1421
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0099 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0064 0.0199
Chlamydia trachomatis cytosol aminopeptidase 0.0237 0.044 0.8068
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0099 0.0326
Brugia malayi photoreceptor-specific nuclear receptor 0.0046 0.0053 0.0157
Entamoeba histolytica exosome component 10, putative 0.0045 0.005 0.0157
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0024 0.0047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0003 0.0004
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0276 0.0519 0.162
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0018 0.0054
Brugia malayi beta-lactamase 0.0038 0.0035 0.0104
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0018 0.0054
Trichomonas vaginalis DNA helicase recq1, putative 0.0434 0.0841 0.2628
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0018 0.0036
Echinococcus granulosus heat shock protein 0.0068 0.0097 0.0123
Entamoeba histolytica rodhanase-like domain containing protein 0.012 0.0202 0.063
Echinococcus granulosus neutral alpha glucosidase AB 0.0159 0.0282 0.036
Loa Loa (eye worm) hypothetical protein 0.0092 0.0146 0.0516
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0009 0.0012
Echinococcus multilocularis SAM and MBT domain containing protein 0.0154 0.0272 0.0272
Brugia malayi nuclear receptor NHR-88 0.0022 0.0003 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.013 0.0223 0.285
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0276 0.0519 0.1026
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0035 0.0069
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0101 0.0163 0.0511
Schistosoma mansoni microtubule-associated protein tau 0.2159 0.4347 0.5552
Plasmodium falciparum importin beta, putative 0.003 0.0019 0.0248
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.0003 0.0011
Leishmania major alpha glucosidase II subunit, putative 0.0159 0.0282 0.0557
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0011
Loa Loa (eye worm) 3'-5' exonuclease 0.0045 0.005 0.0177
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Echinococcus multilocularis lysine specific demethylase 6a 0.0041 0.0042 0.0042
Brugia malayi Hsp90 protein 0.0028 0.0015 0.0045
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Loa Loa (eye worm) hypothetical protein 0.0175 0.0315 0.1112
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0018 0.0036
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.0003 0.0004
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0003 0.0004
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0237 0.044 0.0869
Trichomonas vaginalis sucrase-isomaltase, putative 0.0159 0.0282 0.0879
Entamoeba histolytica hypothetical protein 0.0027 0.0014 0.0043
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0018 0.0021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0779 0.1543 0.5813
Leishmania major importin beta-1 subunit, putative 0.0024 0.0007 0.0015
Leishmania major heat shock protein 83-1 0.0068 0.0097 0.0191
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0055 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0046 0.0053 0.0157
Loa Loa (eye worm) Smad1 0.0027 0.0013 0.0045
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0075 0.011 0.0417
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0237 0.044 0.2793
Trypanosoma brucei WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0028 0.0015 0.003
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0109 0.0386
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.012 0.0202 0.063
Onchocerca volvulus 0.0052 0.0064 0.0441
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0127 0.0252
Brugia malayi Probable ClpP-like protease 0.0077 0.0114 0.0339
Loa Loa (eye worm) follicle stimulating hormone receptor 0.026 0.0487 0.1717
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0009 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0093 0.0119
Schistosoma mansoni rab6-interacting 0.0147 0.0258 0.0329
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0093 0.0119
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0024 0.0047
Plasmodium vivax exosome complex exonuclease RRP6, putative 0.0045 0.005 0.0953
Trichomonas vaginalis ap endonuclease, putative 0.0101 0.0163 0.0511
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0025 0.0079
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.0003 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0018 0.0069
Trichomonas vaginalis DNA polymerase eta, putative 0.0296 0.056 0.175
Leishmania major hypothetical protein, conserved 0.0038 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0187

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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