Detailed information for compound 1098213

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 4283.82 | Formula: C192H301N51O58S
  • H donors: 59 H acceptors: 58 LogP: -23.08 Rotable bonds: 186
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCC(=O)N)CCC(=O)N)CC(C)C)CCCCN)CCCCN)C(C)C)CCC(=O)N)C(C)C)CC(=O)N)CC(=O)N)CCC(=O)N)CCC(=O)O)[C@H](CC)C)CC(=O)N)CCSC)[C@H](CC)C)[C@H](CC)C)CCC(=O)O)Cc1ccc(cc1)O)Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)N)CCC(=O)O)Cc1ccc(cc1)O)CC(=O)N)CCC(=O)N)CCCCN)CCC(=O)O)CC(C)C)CCC(=O)N)CCC(=O)N
  • InChi: 1S/C192H301N51O58S/c1-19-98(14)156(188(296)226-123(60-71-152(264)265)168(276)217-119(54-65-140(201)250)170(278)234-134(87-145(206)255)183(291)237-135(88-146(207)256)184(292)239-155(97(12)13)187(295)225-121(56-67-142(203)252)173(281)238-154(96(10)11)186(294)223-113(41-29-33-76-195)162(270)214-111(39-27-31-74-193)161(269)211-92-149(259)213-127(80-94(6)7)176(284)219-118(53-64-139(200)249)169(277)228-126(192(300)301)57-68-143(204)253)241-185(293)136(89-147(208)257)235-172(280)125(73-78-302-18)227-189(297)157(99(15)20-2)242-190(298)158(100(16)21-3)240-174(282)124(61-72-153(266)267)222-178(286)130(83-103-43-47-106(245)48-44-103)231-179(287)129(82-102-35-23-22-24-36-102)230-164(272)112(40-28-32-75-194)215-166(274)116(51-62-137(198)247)216-167(275)117(52-63-138(199)248)220-177(285)128(81-95(8)9)229-171(279)122(59-70-151(262)263)218-163(271)114(42-30-34-77-196)224-191(299)159(101(17)244)243-175(283)120(55-66-141(202)251)221-182(290)133(86-144(205)254)236-180(288)131(84-104-45-49-107(246)50-46-104)232-181(289)132(85-105-90-209-110-38-26-25-37-108(105)110)233-165(273)115(58-69-150(260)261)212-148(258)91-210-160(268)109(197)79-93(4)5/h22-26,35-38,43-50,90,93-101,109,111-136,154-159,209,244-246H,19-21,27-34,39-42,51-89,91-92,193-197H2,1-18H3,(H2,198,247)(H2,199,248)(H2,200,249)(H2,201,250)(H2,202,251)(H2,203,252)(H2,204,253)(H2,205,254)(H2,206,255)(H2,207,256)(H2,208,257)(H,210,268)(H,211,269)(H,212,258)(H,213,259)(H,214,270)(H,215,274)(H,216,275)(H,217,276)(H,218,271)(H,219,284)(H,220,285)(H,221,290)(H,222,286)(H,223,294)(H,224,299)(H,225,295)(H,226,296)(H,227,297)(H,228,277)(H,229,279)(H,230,272)(H,231,287)(H,232,289)(H,233,273)(H,234,278)(H,235,280)(H,236,288)(H,237,291)(H,238,281)(H,239,292)(H,240,282)(H,241,293)(H,242,298)(H,243,283)(H,260,261)(H,262,263)(H,264,265)(H,266,267)(H,300,301)/t98-,99-,100-,101+,109-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,154-,155-,156-,157-,158-,159-/m0/s1
  • InChiKey: USHYEWKEWDAPFY-HQWBZJHSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0001 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.044 0.4867
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0004 0.0037
Onchocerca volvulus 0.008 0.0122 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0004 0.0003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0004 0.004
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0021 0.0011 0.0011
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0006 0.0337
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0024 0.0015 0.0171
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0021 0.0011 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Trypanosoma brucei Flagellar Member 6 0.0016 0.0001 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0004 0.0037
Schistosoma mansoni biogenic amine receptor 0.0079 0.012 0.1325
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0164 0.9048
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0079 0.012 0.1325
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0021 0.0011 0.0697
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0006 0.0061
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0103 0.0103
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0004 0.0236
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0004 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Schistosoma mansoni retinoic acid receptor RXR 0.0113 0.0184 0.2036
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0004 0.004
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0004 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0004 0.0236
Brugia malayi neuropeptide F receptor 0.0079 0.012 0.1241
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.012 0.1325
Toxoplasma gondii transporter, major facilitator family protein 0.0054 0.0073 0.4471
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0078 0.0117 0.7078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0044 0.0453
Leishmania major protein kinase, putative 0.0016 0.0001 0.0044
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0103 0.0103
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0004 0.004
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0079 0.012 0.1325
Echinococcus multilocularis neuropeptide FF receptor 2 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0078 0.0117 0.7176
Loa Loa (eye worm) G-protein coupled receptor 0.0079 0.012 0.1241
Echinococcus granulosus g-protein coupled receptor 0.0079 0.012 0.1325
Schistosoma mansoni ap endonuclease 0.0018 0.0006 0.0061
Chlamydia trachomatis cysteine--tRNA ligase 0.0078 0.0117 1
Trypanosoma cruzi cAMP binding protein, putative 0.0016 0.0001 0.0044
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0052 0.0536
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0181 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0079 0.012 0.1325
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0004 0.004
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0001 0.0008
Entamoeba histolytica transcription factor BTF3, putative 0.0102 0.0164 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0117 0.1216
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0079 0.012 0.1325
Trypanosoma brucei trypanothione reductase 0.0062 0.0087 0.5344
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.012 0.1325
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0016 0.0001 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0119 0.0195 0.2162
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0004 0.0037
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0004 0.0236
Echinococcus granulosus tachykinin peptides receptor 99D 0.0079 0.012 0.1325
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0044 0.0484
Brugia malayi prostaglandin transporter 0.0054 0.0073 0.0758
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0054 0.0073 0.0809
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Brugia malayi cytochrome P450 0.0017 0.0004 0.004
Echinococcus granulosus neuropeptide receptor 0.0079 0.012 0.1325
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0054 0.0073 0.0809
Echinococcus multilocularis serotonin receptor 0.0079 0.012 0.1325
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0016 0.0001 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.0079 0.012 0.1325
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.012 0.1325
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0004 0.0037
Plasmodium vivax cysteine--tRNA ligase, putative 0.0078 0.0117 0.7176
Loa Loa (eye worm) neuropeptide F receptor 0.0079 0.012 0.1241
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0041 0.0422
Echinococcus multilocularis fmrfamide receptor 0.0079 0.012 0.1325
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0021 0.0011 0.0697
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0078 0.0117 1
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0004 0.0004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0062 0.0087 0.0967
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0072 0.0107 0.1185
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0016 0.0001 0.0044
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Schistosoma mansoni hypothetical protein 0.0033 0.0033 0.037
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0073 0.5987
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0079 0.012 0.1325
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Trichomonas vaginalis mercuric reductase, putative 0.0021 0.0011 0.0593
Onchocerca volvulus 0.0054 0.0073 0.5987
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Brugia malayi Dopamine receptor protein 1 0.0079 0.012 0.1241
Mycobacterium tuberculosis Conserved protein 0.007 0.0103 0.0103
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0016 0.0001 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0016 0.0001 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0006 0.0061
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0103 0.0103
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0024 0.0015 0.0171
Echinococcus granulosus peptide allatostatin:somatostatin 0.0079 0.012 0.1325
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.044 0.4867
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0181 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0021 0.0011 0.0126
Brugia malayi hypothetical protein 0.0249 0.044 0.4558
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0016 0.0001 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0054 0.0073 0.0758
Schistosoma mansoni hypothetical protein 0.0495 0.0904 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Plasmodium falciparum basic transcription factor 3b, putative 0.0102 0.0164 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0072 0.0107 0.1185
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0006 0.041
Brugia malayi G-protein coupled receptor 0.0079 0.012 0.1241
Onchocerca volvulus Protein ultraspiracle homolog 0.0017 0.0004 0.0239
Brugia malayi Cyclic-nucleotide gated cation channel 0.0024 0.0015 0.016
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0044
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0054 0.0073 0.0809
Onchocerca volvulus 0.0017 0.0004 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0164 0.9048
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0073 0.0758
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0041 0.2492
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0034 0.0036 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0004 0.0037
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0078 0.0117 0.1299
Brugia malayi nuclear receptor NHR-88 0.0017 0.0004 0.0037
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0072 0.0107 0.1185
Treponema pallidum cysteinyl-tRNA synthetase 0.0078 0.0117 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0052 0.0536
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Loa Loa (eye worm) hypothetical protein 0.007 0.0103 0.1071
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0004 0.0004
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0024 0.0015 0.0171
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0034 0.0036 0.0399
Plasmodium falciparum cysteine--tRNA ligase 0.0078 0.0117 0.7176
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0087 0.0963
Echinococcus granulosus neuropeptide FF receptor 2 0.0079 0.012 0.1325
Brugia malayi N-terminal motif family protein 0.0016 0.0001 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0004 0.0037
Trypanosoma cruzi cytochrome P450, putative 0.006 0.0085 0.5198
Schistosoma mansoni hypothetical protein 0.0495 0.0904 1
Brugia malayi G-protein coupled receptor 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0004 0.004
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.007 0.0103 0.1071
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni voltage-gated potassium channel 0.013 0.0216 0.239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0004 0.0037
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0021 0.0011 0.0527
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0006 0.0337
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.0015 0.0171
Brugia malayi G protein-coupled receptor 0.0079 0.012 0.1241
Leishmania major cysteinyl-tRNA synthetase, putative 0.0078 0.0117 0.7176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0422
Onchocerca volvulus Bile acid receptor homolog 0.0017 0.0004 0.0239
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0425
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0021 0.0011 0.0697
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0072 0.0107 0.6428
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0004 0.0004
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0072 0.0107 0.1185
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0103 0.1144
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0007
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0109 0.1201
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0004 0.0003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0004 0.004
Echinococcus multilocularis agrin 0.0037 0.0041 0.0451
Onchocerca volvulus 0.0054 0.0073 0.5987
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0103 0.6322
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0044 0.0484
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.012 0.1325
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0103 0.0103
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0079 0.012 0.1241
Echinococcus multilocularis transcription factor btf3 0.0102 0.0164 0.1809
Plasmodium falciparum thioredoxin reductase 0.0021 0.0011 0.0697
Schistosoma mansoni lamin 0.008 0.0122 0.1346
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0079 0.012 0.1325
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0079 0.012 0.1325
Echinococcus granulosus g protein coupled receptor 0.0079 0.012 0.1325
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0021 0.0011 0.0697
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0004 0.0003
Loa Loa (eye worm) RNA binding protein 0.0061 0.0087 0.0902
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0004 0.0236
Echinococcus multilocularis geminin 0.0495 0.0904 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.0011 0.0697
Echinococcus granulosus biogenic amine 5HT receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus neuropeptide s receptor 0.0079 0.012 0.1325
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.016
Trypanosoma cruzi cAMP response protein 1, putative 0.0016 0.0001 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Onchocerca volvulus 0.0051 0.0067 0.5456
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0016 0.0001 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0004 0.004
Toxoplasma gondii NADPH-glutathione reductase 0.0021 0.0011 0.0697
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0004 0.0037
Loa Loa (eye worm) beta-lactamase 0.007 0.0103 0.1071
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0021 0.0011 0.0697
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0113 0.0184 0.2036
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0021 0.0011 0.0697
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0004 0.0004
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0016 0.0001 0.0044
Schistosoma mansoni follistatin 0.0037 0.0041 0.0451
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0004 0.0236
Echinococcus granulosus cGMP dependent protein kinase 0.0016 0.0001 0.0008
Echinococcus granulosus Solute carrier organic anion transporter family 0.0054 0.0073 0.0809
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0448 0.0816 0.0816
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0103 0.0166 0.1718
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0041 0.2492
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0079 0.012 0.1325
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0004 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0004 0.0037
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0079 0.012 0.1241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Leishmania major cyclic nucleotide-binding protein-like protein 0.0016 0.0001 0.0044
Schistosoma mansoni coup transcription factor 0.0017 0.0004 0.004
Echinococcus multilocularis ubiquitin specific protease 41 0.0072 0.0107 0.1185
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0004 0.004
Loa Loa (eye worm) hypothetical protein 0.007 0.0103 0.1071
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0078 0.0117 0.1299
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis lamin dm0 0.008 0.0122 0.1346
Loa Loa (eye worm) hypothetical protein 0.0048 0.0062 0.0646
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0041 0.0422
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0006 0.0337
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0103 0.0103
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0079 0.012 0.1325
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.012 0.1325
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0006 0.0072
Echinococcus granulosus allatostatin A receptor 0.0079 0.012 0.1325
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0016 0.0001 0.0008
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0016 0.0001 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0004 0.004
Onchocerca volvulus 0.007 0.0103 0.8489
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0078 0.0117 0.6482
Brugia malayi beta-lactamase family protein 0.007 0.0103 0.1071
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni hypothetical protein 0.0079 0.012 0.1325
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0004 0.0037
Giardia lamblia NADH oxidase lateral transfer candidate 0.0021 0.0011 0.0915
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0016 0.0001 0.0044
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0004 0.0043
Onchocerca volvulus 0.0079 0.012 0.9844
Schistosoma mansoni hypothetical protein 0.0017 0.0004 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0004 0.0004
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0103 0.1144
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0024 0.0015 0.0171
Echinococcus granulosus 7TM GPCR rhodopsin 0.0079 0.012 0.1325
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0041 0.2492
Loa Loa (eye worm) hypothetical protein 0.0072 0.0107 0.111
Onchocerca volvulus 0.007 0.0103 0.8489
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0079 0.012 0.1241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Brugia malayi Tachykinin-like peptides receptor 99D 0.0079 0.012 0.1241
Schistosoma mansoni amine GPCR 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0001 0.0008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.0011 0.0697
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0072 0.0107 0.111
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0001 0.0008
Brugia malayi Serotonin receptor 0.0079 0.012 0.1241
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0079 0.012 0.1241
Onchocerca volvulus 0.007 0.0103 0.8489
Trypanosoma cruzi transcription factor btf3, putative 0.0102 0.0164 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0021 0.0011 0.0527
Onchocerca volvulus 0.0079 0.012 0.9844
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0016 0.0001 0.0044
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0001 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0079 0.012 0.1325
Echinococcus granulosus neuropeptide Y receptor 0.0079 0.012 0.1325
Brugia malayi beta-lactamase 0.007 0.0103 0.1071
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0103 0.5705
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0004 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0103 0.5705
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.008 0.0122 0.1261
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus cysteinyl tRNA synthetase 0.0078 0.0117 0.1299
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0087 0.0963
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0004 0.0037
Echinococcus granulosus neuropeptide Y receptor 0.0079 0.012 0.1325
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0016 0.0001 0.0008
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0004 0.0003
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0004 0.004
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0006 0.041
Brugia malayi Melatonin receptor type 1A 0.0079 0.012 0.1241
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0016 0.0001 0.0044
Echinococcus granulosus transcription factor btf3 0.0102 0.0164 0.1809
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0119 0.0195 0.2025
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0004 0.0004
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0078 0.0117 0.7176
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0078 0.0117 0.7176
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0016 0.0001 0.0044
Brugia malayi larval opioid receptor 0.0079 0.012 0.1241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Toxoplasma gondii NAC domain-containing protein 0.0102 0.0164 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0072 0.0107 0.9119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0103 0.1144
Echinococcus multilocularis musashi 0.008 0.0122 0.1346
Schistosoma mansoni intermediate filament proteins 0.008 0.0122 0.1346
Brugia malayi AKH receptor 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0425
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0004 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0422
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0004 0.004
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0079 0.012 0.1325
Schistosoma mansoni lamin 0.008 0.0122 0.1346
Echinococcus multilocularis dro:myosuppressin receptor 0.0079 0.012 0.1325
Schistosoma mansoni transcription factor btf3 0.0102 0.0164 0.1809
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0079 0.012 0.1241
Schistosoma mansoni amine GPCR 0.0079 0.012 0.1325
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0041 0.2492
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0085 0.0881
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0004 0.0003
Echinococcus granulosus serotonin receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0004 0.0037
Onchocerca volvulus 0.008 0.0122 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0024 0.0015 0.016
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0004 0.0003
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Brugia malayi glutathione reductase 0.0062 0.0087 0.0906
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0024 0.0015 0.0171
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0087 0.0902
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0006 0.0266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0072 0.0107 0.5911
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0004 0.0003
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0004 0.0236
Trypanosoma cruzi protein kinase A regulatory subunit 0.0016 0.0001 0.0044
Echinococcus granulosus g protein coupled receptor 0.0079 0.012 0.1325
Trypanosoma cruzi cytochrome P450, putative 0.006 0.0085 0.5198
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Leishmania major protein kinase A regulatory subunit, putative 0.0016 0.0001 0.0044
Echinococcus granulosus hyperpolarization activated cyclic 0.0024 0.0015 0.0171
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0016 0.0001 0.0008
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0016 0.0001 0.0007
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0079 0.012 0.9844
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0073 0.5987
Loa Loa (eye worm) agrin synaptic family protein 0.0037 0.0041 0.0422
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0016 0.0001 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0004 0.004
Brugia malayi beta-NAC-like protein 0.0102 0.0164 0.1695
Echinococcus granulosus follistatin 0.0037 0.0041 0.0451
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0004 0.0004
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0107 0.6548
Mycobacterium tuberculosis Conserved protein 0.0016 0.0001 0.0001
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0016 0.0001 0.0008
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0103 0.0103
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0006 0.0266
Loa Loa (eye worm) hypothetical protein 0.0034 0.0036 0.0374
Echinococcus multilocularis G protein coupled receptor 139 0.0079 0.012 0.1325
Schistosoma mansoni organic anion transporter 0.0054 0.0073 0.0809
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0107 0.6548
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0103 0.0103
Schistosoma mansoni ap endonuclease 0.0018 0.0006 0.0061
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Plasmodium falciparum thioredoxin reductase 0.0062 0.0087 0.5344
Brugia malayi hypothetical protein 0.0054 0.0073 0.0758
Echinococcus multilocularis hyperpolarization activated cyclic 0.0024 0.0015 0.0171
Loa Loa (eye worm) TYRA-2 protein 0.0079 0.012 0.1241
Leishmania major cytochrome p450-like protein 0.0017 0.0004 0.0236
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0079 0.012 0.1325
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0004 0.0037
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0062 0.0646
Echinococcus granulosus patatin phospholipase domain containing protein 0.0016 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Loa Loa (eye worm) neuropeptide F receptor 0.0079 0.012 0.1241
Schistosoma mansoni histamine h1 receptor 0.0079 0.012 0.1325
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0004 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0087 0.0963
Trypanosoma brucei cAMP binding protein, putative 0.0016 0.0001 0.0044
Plasmodium vivax basic transcription factor 3b, putative 0.0102 0.0164 1
Echinococcus granulosus sex peptide receptor 0.0079 0.012 0.1325
Echinococcus multilocularis neuropeptide receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) AGC/PKG protein kinase 0.0016 0.0001 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0004 0.0004
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0001 0.0008
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0024 0.0015 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0016 0.0001 0.0044
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0103 0.1071
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0073 0.0758
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0033 0.0347
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0006 0.0072
Onchocerca volvulus 0.0079 0.012 0.9844
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0015 0.082
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0078 0.0117 0.1216
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Mycobacterium ulcerans hypothetical protein 0.007 0.0103 0.0103
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus fmrfamide receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.008 0.0122 0.1261
Brugia malayi TAR-binding protein 0.0061 0.0087 0.0902
Brugia malayi Cytochrome P450 family protein 0.006 0.0085 0.0881
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Loa Loa (eye worm) thioredoxin reductase 0.0062 0.0087 0.0906
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0073 0.0758
Echinococcus multilocularis orexin receptor type 2 0.0079 0.012 0.1325
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0044
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.5322 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0021 0.0011 0.0697
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0004 0.0037
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0006 0.0337
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0006 0.0057
Plasmodium falciparum glutathione reductase 0.0021 0.0011 0.0697
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0016 0.0001 0.0007
Leishmania major hypothetical protein, unknown function 0.0016 0.0001 0.0044
Echinococcus multilocularis somatostatin receptor 0.0079 0.012 0.1325
Onchocerca volvulus 0.0079 0.012 0.9844
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0041 0.0422
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0067 0.0691
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.0001 0.0008
Brugia malayi G protein-coupled receptor F59B2.13 0.0079 0.012 0.1241
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0004 0.0037
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0004 0.0037
Echinococcus multilocularis expressed protein 0.0037 0.0041 0.0451
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Brugia malayi Dopamine receptor protein 2 0.0079 0.012 0.1241
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0107 0.6548
Echinococcus multilocularis g-protein coupled receptor 0.0079 0.012 0.1325
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0021 0.0011 0.0126
Schistosoma mansoni neuropeptide F-like receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.0015 0.0171
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0021 0.0011 0.0126
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0015 0.0171
Mycobacterium leprae putative cytochrome p450 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0079 0.012 0.1325
Echinococcus granulosus hypothetical protein 0.0079 0.012 0.1325
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0062 0.0646
Schistosoma mansoni voltage-gated potassium channel 0.013 0.0216 0.239
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.0001 0.0008
Toxoplasma gondii protease inhibitor PI2 0.0037 0.0041 0.2492
Brugia malayi putative neuropeptide receptor NPR1 0.0079 0.012 0.1241
Echinococcus granulosus geminin 0.0495 0.0904 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.007 0.0103 0.1071
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0109 0.1201
Schistosoma mansoni neuropeptide f receptor 76f 0.0079 0.012 0.1325
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0017 0.0004 0.0239
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0016 0.0001 0.0008
Mycobacterium leprae Probable lipase LipE 0.007 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0104 0.0167 0.1846
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0107 0.5911
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0004 0.0003
Brugia malayi Cytochrome P450 family protein 0.0017 0.0004 0.004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0024 0.0015 0.016
Plasmodium vivax glutathione reductase, putative 0.0062 0.0087 0.5344
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Echinococcus granulosus ubiquitin specific protease 41 0.0072 0.0107 0.1185
Trypanosoma cruzi transcription factor btf3, putative 0.0102 0.0164 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0021 0.0011 0.0915
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0004 0.0004
Echinococcus granulosus G protein coupled receptor 139 0.0079 0.012 0.1325
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0079 0.012 0.1325
Echinococcus multilocularis neuropeptide receptor A26 0.0079 0.012 0.1325
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0072 0.0107 0.5911
Echinococcus granulosus neuropeptides capa receptor 0.0079 0.012 0.1325
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0072 0.0107 0.1185
Brugia malayi putative neuropeptide receptor 0.0079 0.012 0.1241
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0103 0.1071
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0103 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Onchocerca volvulus 0.0079 0.012 0.9844
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0016 0.0001 0.0008
Brugia malayi ecdysteroid receptor 0.0017 0.0004 0.0037
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0016 0.0001 0.0001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0079 0.012 0.1325
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0079 0.012 0.1325
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0087 0.0963
Loa Loa (eye worm) hypothetical protein 0.007 0.0103 0.1071
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0087 0.0902
Schistosoma mansoni hypothetical protein 0.0016 0.0001 0.0008
Mycobacterium tuberculosis Conserved protein 0.007 0.0103 0.0103
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0078 0.0117 0.7176
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0004 0.004
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0119 0.0195 0.2025
Loa Loa (eye worm) hypothetical protein 0.0078 0.0119 0.1232
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0021 0.0011 0.0011
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0079 0.012 0.1325
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0034 0.0036 0.0399
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0079 0.012 0.1325
Echinococcus multilocularis 0.0017 0.0004 0.0043
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.0001 0.0008
Schistosoma mansoni hypothetical protein 0.0079 0.012 0.1325
Brugia malayi Dopamine receptor 0.0079 0.012 0.1241
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0103 0.6322
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0004 0.0004
Brugia malayi RE15519p 0.0079 0.012 0.1241
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0004 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0016 0.0001 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Brugia malayi beta-lactamase family protein 0.007 0.0103 0.1071
Echinococcus granulosus biogenic amine 5HT receptor 0.0079 0.012 0.1325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Onchocerca volvulus 0.0054 0.0073 0.5987
Brugia malayi Serotonin receptor 0.0079 0.012 0.1241
Schistosoma mansoni amine GPCR 0.0079 0.012 0.1325
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0006 0.0337
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Onchocerca volvulus 0.0037 0.0041 0.331
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0016 0.0001 0.0007
Plasmodium vivax hypothetical protein, conserved 0.007 0.0103 0.6322
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0006 0.0337
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0079 0.012 0.1325
Brugia malayi sulfakinin receptor protein 0.0079 0.012 0.1241
Loa Loa (eye worm) intermediate filament protein 0.008 0.0122 0.1261
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0078 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Leishmania major basic transcription factor 3a, putative 0.0102 0.0164 1
Brugia malayi hypothetical protein 0.0054 0.0073 0.0758
Echinococcus granulosus tar DNA binding protein 0.0061 0.0087 0.0963
Loa Loa (eye worm) G-protein coupled receptor 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus hyperpolarization activated cyclic 0.0024 0.0015 0.0171
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0103 0.5705
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus leucyl tRNA synthetase 0.0078 0.0117 0.1299
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0021 0.0011 0.0697
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0087 0.0963
Onchocerca volvulus 0.0079 0.012 0.9844
Leishmania major cytochrome p450-like protein 0.0017 0.0004 0.0236
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0072 0.0107 0.1185
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0036 0.0399
Plasmodium falciparum glutathione reductase 0.0062 0.0087 0.5344
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0079 0.012 0.1325
Schistosoma mansoni hypothetical protein 0.0051 0.0067 0.0738
Onchocerca volvulus 0.0079 0.012 0.9844
Brugia malayi Cytochrome P450 family protein 0.0017 0.0004 0.004
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0024 0.0015 0.0171
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.0001 0.0008
Loa Loa (eye worm) glutathione reductase 0.0062 0.0087 0.0906
Schistosoma mansoni neuropeptide receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0004 0.004
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0015 0.082
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0079 0.012 0.1241
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0079 0.012 0.1325
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0078 0.0117 0.1216
Schistosoma mansoni biogenic amine receptor 0.0079 0.012 0.1325
Schistosoma mansoni neuropeptide receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0103 0.5705
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0004 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0079 0.012 0.1325
Schistosoma mansoni opsin-like receptor 0.0079 0.012 0.1325
Brugia malayi RNA binding protein 0.0061 0.0087 0.0902
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.5322 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0001 0.0008
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0079 0.012 0.1325
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0021 0.0011 0.0697
Schistosoma mansoni neuropeptide receptor 0.0079 0.012 0.1325
Trypanosoma cruzi MFS transporter, putative 0.0054 0.0073 0.4471
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0087 0.0902
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0016 0.0001 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Echinococcus multilocularis neuropeptide Y receptor 0.0079 0.012 0.1325
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0004 0.004
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0004 0.0004
Giardia lamblia Cysteinyl-tRNA synthetase 0.0078 0.0117 1
Trypanosoma brucei transcription factor BTF3, putative 0.0102 0.0164 1
Brugia malayi Cytochrome P450 family protein 0.006 0.0085 0.0881
Brugia malayi steroid hormone receptor 0.0017 0.0004 0.0037
Schistosoma mansoni survival motor neuron protein 0.0051 0.0067 0.0738
Onchocerca volvulus Neuropeptide F receptor homolog 0.0079 0.012 0.9844
Echinococcus granulosus agrin 0.0037 0.0041 0.0451
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0422
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0079 0.012 0.1325
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Plasmodium falciparum cGMP-dependent protein kinase 0.0016 0.0001 0.0044
Plasmodium falciparum cysteine--tRNA ligase 0.0078 0.0117 0.7176
Echinococcus granulosus intermediate filament protein 0.008 0.0122 0.1346
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0016 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis lamin 0.008 0.0122 0.1346
Schistosoma mansoni biogenic amine (5HT) receptor 0.0079 0.012 0.1325
Leishmania major hypothetical protein, conserved 0.007 0.0103 0.6322
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0085 0.0881
Echinococcus granulosus orexin receptor type 2 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Leishmania major protein kinase, putative 0.0016 0.0001 0.0044
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0004 0.004
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0016 0.0001 0.0007
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0079 0.012 0.1325
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0079 0.012 0.1241
Brugia malayi Egg laying defective protein 4 0.0016 0.0001 0.0007
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0016 0.0001 0.0044
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Entamoeba histolytica hypothetical protein 0.0102 0.0164 1
Schistosoma mansoni cytochrome P450 0.0017 0.0004 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0347
Schistosoma mansoni neuropeptide F-like receptor 0.0079 0.012 0.1325
Onchocerca volvulus 0.0079 0.012 0.9844
Brugia malayi neuropeptide F receptor 0.0079 0.012 0.1241
Echinococcus granulosus 7tm_1 domain containing protein 0.0079 0.012 0.1325
Mycobacterium ulcerans lipase LipD 0.007 0.0103 0.0103
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0011 0.0697
Schistosoma mansoni agrin 0.0037 0.0041 0.0451
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0024 0.0015 0.0171
Echinococcus multilocularis fmrfamide receptor 0.0079 0.012 0.1325
Trypanosoma brucei protein kinase A regulatory subunit 0.0016 0.0001 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0004 0.0037
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0004 0.0037
Onchocerca volvulus 0.0054 0.0073 0.5987
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0016 0.0001 0.0044
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0016 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0079 0.012 0.1325
Echinococcus multilocularis neuropeptide s receptor 0.0079 0.012 0.1325
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.012 0.1325
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.0015 0.0171
Echinococcus multilocularis sex peptide receptor 0.0079 0.012 0.1325
Schistosoma mansoni hypothetical protein 0.0051 0.0066 0.0736
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0016 0.0001 0.0044
Loa Loa (eye worm) CYP4Cod1 0.006 0.0085 0.0881
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0016 0.0001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0164 0.9048
Brugia malayi ORL1-like opioid receptor 0.0079 0.012 0.1241
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0011 0.0011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0422
Echinococcus multilocularis voltage gated potassium channel 0.0034 0.0036 0.0399
Brugia malayi Thioredoxin reductase 0.0062 0.0087 0.0906
Mycobacterium tuberculosis Conserved protein 0.007 0.0103 0.0103
Echinococcus multilocularis follistatin 0.0037 0.0041 0.0451
Onchocerca volvulus 0.0079 0.012 0.9844
Echinococcus granulosus dro:myosuppressin receptor 0.0079 0.012 0.1325
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0021 0.0011 0.0011
Echinococcus granulosus lamin 0.008 0.0122 0.1346
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0062 0.0087 0.0087
Toxoplasma gondii thioredoxin reductase 0.0062 0.0087 0.5344
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0119 0.0195 0.2162
Schistosoma mansoni neuropeptide receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0004 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0004 0.004
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0004 0.0003
Plasmodium vivax thioredoxin reductase, putative 0.0062 0.0087 0.5344
Echinococcus multilocularis neuropeptide receptor 0.0079 0.012 0.1325
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0041 0.0422
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0004 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.012 0.1325
Schistosoma mansoni opsin-like receptor 0.0079 0.012 0.1325
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0004 0.004
Schistosoma mansoni hypothetical protein 0.0079 0.012 0.1325
Schistosoma mansoni amine GPCR 0.0079 0.012 0.1325
Toxoplasma gondii ABC1 family protein 0.007 0.0103 0.6322
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0004 0.004
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0021 0.0011 0.0697
Schistosoma mansoni adenoreceptor 0.0079 0.012 0.1325
Echinococcus multilocularis G-protein coupled receptor, putative 0.0079 0.012 0.1325
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0036 0.0399
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0004 0.004
Leishmania major trypanothione reductase 0.0062 0.0087 0.5344
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.0011 0.0697
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0004 0.0003
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0078 0.0117 0.1299
Trypanosoma cruzi cAMP response protein 1 0.0016 0.0001 0.0044
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0041 0.0422
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0062 0.0646
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Onchocerca volvulus 0.0079 0.012 0.9844
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0004 0.0004
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0006 0.0006
Onchocerca volvulus 0.0078 0.0117 0.9644
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0087 0.5344
Echinococcus multilocularis serotonin receptor 0.0079 0.012 0.1325
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0079 0.012 0.1325
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0079 0.012 0.1325
Toxoplasma gondii exonuclease III APE 0.0018 0.0006 0.0337
Onchocerca volvulus 0.0079 0.012 0.9844
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0004 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0004 0.004
Brugia malayi secreted modular calcium-binding protein 1 0.0037 0.0041 0.0422
Leishmania major regulatory subunit of protein kinase a-like protein 0.0016 0.0001 0.0044
Mycobacterium leprae conserved hypothetical protein 0.007 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0087 0.0963
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0073 0.5987
Loa Loa (eye worm) melatonin receptor type 1A 0.0079 0.012 0.1241
Onchocerca volvulus 0.0079 0.012 0.9844
Onchocerca volvulus 0.0079 0.012 0.9844
Brugia malayi GnHR receptor homolog 0.0079 0.012 0.1241
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0004 0.0003
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0016 0.0001 0.0007
Schistosoma mansoni growth hormone secretagogue receptor 0.0079 0.012 0.1325
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0016 0.0001 0.0008
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus granulosus neuropeptide receptor 0.0079 0.012 0.1325
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0016 0.0001 0.0044
Treponema pallidum NADH oxidase 0.0021 0.0011 0.0915
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0004 0.004
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis g protein coupled receptor 0.0079 0.012 0.1325
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni organic anion transporter 0.0054 0.0073 0.0809
Brugia malayi intermediate filament protein 0.008 0.0122 0.1261
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.012 0.1325
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0004 0.0003
Schistosoma mansoni amine GPCR 0.0079 0.012 0.1325
Trypanosoma brucei cytochrome P450, putative 0.006 0.0085 0.5198
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0021 0.0011 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0004 0.0004
Trypanosoma cruzi Flagellar Member 6 0.0016 0.0001 0.0044
Brugia malayi nuclear hormone receptor 0.0017 0.0004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0541
Echinococcus granulosus alpha 1A adrenergic receptor 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis expressed conserved protein 0.0016 0.0001 0.0008
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0527 0.0965 1
Echinococcus multilocularis allatostatin A receptor 0.0079 0.012 0.1325
Brugia malayi Intermediate filament tail domain containing protein 0.008 0.0122 0.1261
Brugia malayi hypothetical protein 0.0079 0.012 0.1241
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0103 0.5705
Loa Loa (eye worm) cytochrome P450 0.0017 0.0004 0.004
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0004 0.0003
Brugia malayi follicle stimulating hormone receptor 0.0527 0.0965 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0007
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0016 0.0001 0.0008
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0004 0.004
Onchocerca volvulus 0.0054 0.0073 0.5987
Echinococcus multilocularis neuropeptides capa receptor 0.0079 0.012 0.1325
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.012 0.1325
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0021 0.0011 0.0011
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0103 0.1144
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0072 0.0107 0.6548
Echinococcus granulosus somatostatin receptor 0.0079 0.012 0.1325
Mycobacterium ulcerans beta-lactamase 0.007 0.0103 0.0103
Echinococcus granulosus lamin dm0 0.008 0.0122 0.1346
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.0011 0.0697
Brugia malayi SPARC precursor 0.0037 0.0041 0.0422
Echinococcus granulosus g protein coupled receptor 0.0079 0.012 0.1325
Schistosoma mansoni hypothetical protein 0.0079 0.012 0.1325
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0021 0.0011 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0103 0.6322
Trichomonas vaginalis glutathione reductase, putative 0.0021 0.0011 0.0593
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0004 0.0004
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0016 0.0001 0.0001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0006 0.0057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0004 0.004
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0016 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.007 0.0103 0.1071
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.006 0.0085 0.0084
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0079 0.012 0.1325
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0024 0.0015 0.0171
Trichomonas vaginalis esterase, putative 0.007 0.0103 0.5705
Echinococcus multilocularis hyperpolarization activated cyclic 0.0024 0.0015 0.0171
Leishmania major cytochrome p450-like protein 0.006 0.0085 0.5198
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.012 0.1325
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0004 0.004
Loa Loa (eye worm) ICD-1 protein 0.0102 0.0164 0.1695
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0004 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0758
Onchocerca volvulus 0.0079 0.012 0.9844
Schistosoma mansoni biogenic amine (5HT) receptor 0.0079 0.012 0.1325
Schistosoma mansoni biogenic amine receptor 0.0079 0.012 0.1325
Trypanosoma brucei cAMP response protein 1, putative 0.0016 0.0001 0.0044
Onchocerca volvulus 0.0079 0.012 0.9844
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0103 0.0103
Echinococcus granulosus thioredoxin glutathione reductase 0.0062 0.0087 0.0967
Onchocerca volvulus 0.0079 0.012 0.9844
Onchocerca volvulus 0.0079 0.012 0.9844
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0016 0.0001 0.0044
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0001 0.0008
Echinococcus granulosus neuropeptide receptor A26 0.0079 0.012 0.1325
Schistosoma mansoni alpha-1 adrenergic receptor 0.0079 0.012 0.1325
Schistosoma mansoni myosin xvIII 0.0079 0.012 0.1325
Loa Loa (eye worm) hypothetical protein 0.0079 0.012 0.1241
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.012 0.1325
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0044
Loa Loa (eye worm) hypothetical protein 0.0249 0.044 0.4558
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0037
Schistosoma mansoni opsin-like receptor 0.0079 0.012 0.1325
Echinococcus granulosus voltage gated potassium channel 0.0034 0.0036 0.0399

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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