Detailed information for compound 110001

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 480.997 | Formula: C26H34ClFO5
  • H donors: 1 H acceptors: 4 LogP: 4.16 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(=O)O[C@@]1([C@@H](C)CC2C1(C)CC(O)[C@]1(C2CCC2=CC(=O)C=CC12C)F)C(=O)CCl
  • InChi: 1S/C26H34ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-20,30H,5-8,11,13-14H2,1-4H3/t15-,18?,19?,20?,23?,24?,25-,26-/m0/s1
  • InChiKey: DERCOWNWEPPIHD-XYWQMIARSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ecdysone induced protein 78C 0.0085 0.0055 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Schistosoma mansoni transcription factor btf3 0.0035 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0085 0.0055 0.0054
Leishmania major protein kinase, putative 0.0021 0.0002 0.0002
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0003 0.0002
Brugia malayi Probable isocitrate dehydrogenase 0.0095 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus thymidylate synthase 0.2969 0.2441 0.2441
Mycobacterium leprae Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS) 0.0034 0.0013 0.0011
Mycobacterium leprae putative cytochrome p450 0.0044 0.0021 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.01 0.0068 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.006 0.006
Schistosoma mansoni ap endonuclease 0.0019 0 0.0000094845
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0085 0.0055 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0044 0.0021 0.0021
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0039 0.0016 0.0016
Brugia malayi Carboxylesterase family protein 0.01 0.0067 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0046 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0013 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Echinococcus multilocularis cpg binding protein 0.0053 0.0028 0.0028
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.003 0.0029
Schistosoma mansoni hypothetical protein 0.0708 0.057 0.057
Giardia lamblia Ribokinase 0.0189 0.0141 0.382
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0021 0.0002 0.0002
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0785 0.0634 0.0634
Mycobacterium ulcerans 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.0065 0.0038 0.0037
Onchocerca volvulus 0.015 0.0108 0.0436
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0011 0.0011
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0024 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 1.2103 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.015 0.0108 0.0108
Schistosoma mansoni histamine h1 receptor 0.015 0.0108 0.0108
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0115 0.008 0.008
Brugia malayi Carboxylesterase family protein 0.0594 0.0476 0.0476
Echinococcus multilocularis neuropeptides capa receptor 0.015 0.0108 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis ubiquitin specific protease 41 0.0047 0.0023 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0044 0.0021 0.0029
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Echinococcus multilocularis nuclear receptor nhr 48 0.004 0.0018 0.0017
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0463 0.0368 0.3187
Schistosoma mansoni thyroid hormone receptor 0.0085 0.0055 0.0054
Trypanosoma cruzi adenosine kinase, putative 0.0189 0.0141 0.0202
Schistosoma mansoni hypothetical protein 0.015 0.0108 0.0108
Entamoeba histolytica kinase, PfkB family 0.0189 0.0141 0.382
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0013 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0059 0.0033 0.0033
Entamoeba histolytica hypothetical protein 0.0261 0.0201 0.5452
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0021 0.0002 0.0011
Trichomonas vaginalis guanylate cyclase, putative 0.0021 0.0002 0.0011
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0463 0.0368 0.0367
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0131 0.0092 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0003 0.0002
Plasmodium vivax replication factor C subunit 1, putative 0.0023 0.0004 0.0005
Brugia malayi Carboxylesterase family protein 0.01 0.0067 0.0067
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0079 0.005 0.005
Echinococcus granulosus expressed conserved protein 0.0228 0.0173 0.0173
Onchocerca volvulus Matrix metalloproteinase homolog 0.0034 0.0012 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0085 0.0055 0.0054
Schistosoma mansoni hypothetical protein 0.0079 0.005 0.005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.015 0.0108 0.0108
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.015 0.0108 0.0108
Trypanosoma brucei adenosine kinase, putative 0.1658 0.1356 0.1947
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0013 0.0019
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0463 0.0368 0.3187
Brugia malayi follicle stimulating hormone receptor 0.015 0.0108 0.0108
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Echinococcus multilocularis beta hexosaminidase subunit alpha 0.0217 0.0164 0.0164
Loa Loa (eye worm) peptidase family M1 containing protein 0.0311 0.0242 0.0242
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0085 0.0055 0.0054
Leishmania major DNA polymerase eta, putative 0.0037 0.0015 0.0021
Onchocerca volvulus Ribokinase homolog 0.0189 0.0141 0.0568
Trypanosoma cruzi aminopeptidase, putative 0.0311 0.0242 0.0347
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Toxoplasma gondii aminopeptidase N protein 0.0311 0.0242 0.0347
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.01 0.0068 0.0067
Echinococcus granulosus tm gpcr rhodopsin 0.015 0.0108 0.0108
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0023 0.0004 0.0003
Loa Loa (eye worm) dihydrofolate reductase 1.2103 1 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.004 0.0018 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0044 0.0021 0.0021
Echinococcus multilocularis replication factor c subunit 1 0.0023 0.0004 0.0003
Schistosoma mansoni sodium/hydrogen exchanger 0.0039 0.0016 0.0016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0085 0.0055 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0603 0.0483 0.0483
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.003 0.0029
Echinococcus granulosus neuropeptide receptor 0.015 0.0108 0.0108
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0075 0.0046 0.0046
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0047 0.0023 0.0033
Trichomonas vaginalis set domain proteins, putative 0.0271 0.0209 0.1807
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0594 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0004 0.0028
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.001
Brugia malayi hypothetical protein 0.0023 0.0004 0.0003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0082 0.0052 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.1412 0.1153 1
Brugia malayi hypothetical protein 0.0189 0.0141 0.014
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0276 0.0213 0.0305
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0143 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0055 0.003 0.0029
Brugia malayi hypothetical protein 0.0261 0.0201 0.02
Echinococcus multilocularis thymidylate synthase 0.2969 0.2441 0.2441
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Schistosoma mansoni sodium/chloride dependent transporter 0.0059 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0079 0.005 0.005
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0044 0.0021 0.0021
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0024 0.0024
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Brugia malayi Pax transcription activation domain interacting protein 0.0023 0.0004 0.0003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0785 0.0634 0.0634
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0015 0.0021
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0047 0.0023 0.0023
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0311 0.0242 0.0347
Echinococcus granulosus dnaJ subfamily B 0.0708 0.057 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Brugia malayi neuropeptide F receptor 0.015 0.0108 0.0108
Schistosoma mansoni nuclear receptor 0.004 0.0018 0.0017
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.003 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.015 0.0108 0.0108
Echinococcus granulosus acetylcholinesterase 0.0594 0.0476 0.0476
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.015 0.0108 0.0108
Schistosoma mansoni inositol monophosphatase 0.0034 0.0013 0.0012
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0003 0.0001
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0 0.0000094845
Toxoplasma gondii histone lysine methyltransferase SET1 0.0095 0.0063 0.0091
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Loa Loa (eye worm) hypothetical protein 0.0081 0.0051 0.0051
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0039 0.0016 0.0016
Brugia malayi PAS domain containing protein 0.0042 0.0019 0.0019
Echinococcus granulosus thyrotropin releasing hormone receptor 0.015 0.0108 0.0108
Echinococcus granulosus sex peptide receptor 0.015 0.0108 0.0108
Leishmania major basic transcription factor 3a, putative 0.0035 0.0013 0.0019
Trypanosoma brucei pteridine reductase 1 0.0364 0.0286 0.041
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0115 0.008 0.0078
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0785 0.0634 0.0634
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0064 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0052 0.0027 0.0027
Onchocerca volvulus 0.015 0.0108 0.0436
Toxoplasma gondii thioredoxin reductase 0.0045 0.0022 0.0031
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0035 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0044 0.0021 0.0021
Onchocerca volvulus 0.0311 0.0242 0.0983
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0013 0.0112
Echinococcus granulosus neuropeptide s receptor 0.0705 0.0568 0.0568
Schistosoma mansoni tar DNA-binding protein 0.0171 0.0126 0.0126
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0594 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Entamoeba histolytica hypothetical protein 0.0261 0.0201 0.5452
Schistosoma mansoni retinoic acid receptor RXR 0.0085 0.0055 0.0054
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.015 0.0108 0.0108
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.015 0.0108 0.0108
Echinococcus granulosus neuropeptide receptor A26 0.0705 0.0568 0.0568
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0085 0.0055 0.0054
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0095 0.0063 0.0546
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0044 0.0021 0.0021
Brugia malayi RE15519p 0.015 0.0108 0.0108
Onchocerca volvulus 0.01 0.0067 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0044 0.0021 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.015 0.0108 0.0108
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0143 0.0103 0.0147
Echinococcus multilocularis G-protein coupled receptor, putative 0.015 0.0108 0.0108
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0056 0.0031 0.0029
Leishmania major adenosine kinase-like protein 0.0189 0.0141 0.0202
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0023 0.0023
Schistosoma mansoni gliotactin 0.01 0.0067 0.0067
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0013 0.0018
Brugia malayi Thioredoxin reductase 0.0045 0.0022 0.0022
Leishmania major dihydrofolate reductase-thymidylate synthase 0.8434 0.6964 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0056 0.0031 0.003
Loa Loa (eye worm) solute carrier family 6 member 4 0.0059 0.0033 0.0033
Trichomonas vaginalis beta-hexosaminidase, putative 0.0217 0.0164 0.1422
Mycobacterium tuberculosis Probable reductase 0.0104 0.007 0.007
Schistosoma mansoni zinc finger protein 0.004 0.0018 0.0017
Brugia malayi isocitrate dehydrogenase 0.0785 0.0634 0.0634
Onchocerca volvulus 0.0123 0.0086 0.0344
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0045 0.0022 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0028 0.0028
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.5857 0.4831 0.4831
Schistosoma mansoni hypothetical protein 0.0033 0.0011 0.0011
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0143 0.0102 0.0147
Loa Loa (eye worm) norepinephrine transporter 0.0059 0.0033 0.0033
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0003 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0044 0.0021 0.0029
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0045 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0095 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0001
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0031 0.001 0.001
Echinococcus multilocularis neuropeptide receptor A26 0.0705 0.0568 0.0568
Treponema pallidum sodium- and chloride- dependent transporter 0.0059 0.0033 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0017 0.0016
Echinococcus multilocularis geminin 0.08 0.0646 0.0646
Entamoeba histolytica hypothetical protein 0.0023 0.0004 0.0087
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0217 0.0164 0.1422
Schistosoma mansoni neuropeptide receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) steroid hormone receptor 0.0085 0.0055 0.0054
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0311 0.0242 0.0347
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0463 0.0368 0.3187
Echinococcus multilocularis neuropeptides capa receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) matrixin family protein 0.0034 0.0012 0.0012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0107 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0013 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0055 0.0054
Echinococcus granulosus dna polymerase kappa 0.0039 0.0017 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.004 0.0018 0.0017
Brugia malayi ORL1-like opioid receptor 0.015 0.0108 0.0108
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0017 0.0446
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0131 0.0092 0.0092
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0035 0.005
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0311 0.0242 0.2095
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0038 0.0037
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.015 0.0108 0.0108
Brugia malayi putative neuropeptide receptor NPR1 0.015 0.0108 0.0108
Plasmodium vivax SET domain protein, putative 0.0035 0.0013 0.0019
Toxoplasma gondii kinase, pfkB family protein 0.1658 0.1356 0.1947
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0017 0.0016
Toxoplasma gondii dihydropteroate synthase 0.0157 0.0114 0.0164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.006 0.006
Brugia malayi hypothetical protein 0.0031 0.001 0.001
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0056 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) transcription factor SMAD2 0.0282 0.0217 0.0217
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0015 0.0021
Echinococcus granulosus survival motor neuron protein 1 0.0603 0.0483 0.0483
Schistosoma mansoni topbp1 0.0023 0.0004 0.0003
Brugia malayi cytochrome P450 0.0044 0.0021 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.015 0.0108 0.0108
Schistosoma mansoni amine GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.015 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0002 0.0011
Entamoeba histolytica hypothetical protein 0.0035 0.0013 0.0352
Echinococcus granulosus BC026374 protein S09 family 0.01 0.0067 0.0067
Brugia malayi Serotonin receptor 0.015 0.0108 0.0108
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0046 0.0045
Echinococcus granulosus leukotriene A 4 hydrolase 0.5857 0.4831 0.4831
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0005 0.0004
Echinococcus granulosus para nitrobenzyl esterase 0.01 0.0067 0.0067
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0003 0.0003
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.003 0.001 0.0008
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.015 0.0108 0.0108
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0785 0.0634 0.091
Mycobacterium tuberculosis Hypothetical protein 0.1412 0.1153 0.1153
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0075 0.0046 0.0046
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0017 0.0024
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0131 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0079 0.005 0.005
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0046 0.0066
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0013 0.0018
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.005 0.005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0082 0.0052 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Echinococcus granulosus 7tm_1 domain containing protein 0.015 0.0108 0.0108
Onchocerca volvulus 0.01 0.0067 0.0268
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.006 0.006
Echinococcus multilocularis g protein coupled receptor 0.015 0.0108 0.0108
Onchocerca volvulus 0.0075 0.0046 0.018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0085 0.0055 0.0054
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.015 0.0108 0.0108
Leishmania major cathepsin L-like protease 0.0065 0.0039 0.0055
Onchocerca volvulus Neuropeptide F receptor homolog 0.015 0.0108 0.0436
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0003 0.0003
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0003 0.0002
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Brugia malayi nuclear hormone receptor family member odr-7 0.004 0.0018 0.0017
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0011 0.0011
Onchocerca volvulus Bile acid receptor homolog 0.0085 0.0055 0.0215
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0017 0.0017
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0033 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0095 0.0063 1
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.2969 0.2441 0.2441
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.004 0.0018 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0023 0.0199
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0044 0.0021 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0013 0.0013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0018 0.0063
Schistosoma mansoni amine GPCR 0.015 0.0108 0.0108
Onchocerca volvulus 0.0048 0.0024 0.009
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0017 0.0017
Schistosoma mansoni amine GPCR 0.015 0.0108 0.0108
Echinococcus granulosus single minded 2 0.0028 0.0008 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0785 0.0634 0.091
Leishmania major hypothetical protein, conserved 0.0034 0.0013 0.0018
Loa Loa (eye worm) hypothetical protein 0.0067 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0085 0.0055 0.0054
Echinococcus granulosus hypothetical protein 0.015 0.0108 0.0108
Brugia malayi Cytochrome P450 family protein 0.0086 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Onchocerca volvulus 0.01 0.0067 0.0268
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0095 0.0063 0.0063
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0463 0.0368 1
Echinococcus granulosus intermediate filament protein 0.0033 0.0011 0.0011
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0039 0.0016 0.0016
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0003 0.0003
Onchocerca volvulus 0.0463 0.0368 0.1499
Echinococcus granulosus tumor protein p63 0.0861 0.0697 0.0697
Echinococcus granulosus family S9 non peptidase ue S09 family 0.01 0.0067 0.0067
Onchocerca volvulus Matrilysin homolog 0.0034 0.0012 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0044 0.0021 0.0029
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0023 0.0023
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0044 0.0021 0.0021
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0003 0.0002
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0024 0.0024
Echinococcus multilocularis transfer RNA-Lys 0.0021 0.0002 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0085 0.0055 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Trypanosoma cruzi membrane transporter protein, putative 0.0034 0.0013 0.0018
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.015 0.0108 0.0108
Trypanosoma brucei Aminopeptidase M1, putative 0.0311 0.0242 0.0347
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0077 0.0048 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0307 0.0239 0.0239
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0018 0.0017
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Mycobacterium leprae Probable2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin 0.0065 0.0038 0.0036
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0023 0.0004 0.0028
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0013 0.0019
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0003 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.007 0.0068
Brugia malayi ecdysone receptor 0.004 0.0018 0.0017
Onchocerca volvulus 0.2969 0.2441 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0056 0.0031 0.0043
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0003 0.0003
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0003 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.0085 0.0055 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0035 0.0035
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0059 0.0033 0.0033
Trypanosoma cruzi aminopeptidase, putative 0.0311 0.0242 0.0347
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0021 0.003
Mycobacterium tuberculosis Ribokinase RbsK 0.0189 0.0141 0.0141
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Echinococcus multilocularis 0.0044 0.0021 0.0021
Echinococcus multilocularis survival motor neuron protein 1 0.0603 0.0483 0.0483
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0021 0.0002 0.0002
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0463 0.0368 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0013 0.0017
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0085 0.0055 0.0054
Echinococcus granulosus tar DNA binding protein 0.0171 0.0126 0.0126
Mycobacterium ulcerans dihydropteroate synthase 2 FolP2 0.0034 0.0013 0.0012
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0463 0.0368 0.0367
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0021 0.0019
Brugia malayi larval opioid receptor 0.015 0.0108 0.0108
Echinococcus multilocularis isocitrate dehydrogenase 0.0785 0.0634 0.0634
Brugia malayi Melatonin receptor type 1A 0.015 0.0108 0.0108
Brugia malayi Adenosine kinase-like 0.1658 0.1356 0.1356
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0018 0.0017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0085 0.0055 0.0054
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0017 0.0016
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0095 0.0063 0.0063
Schistosoma mansoni cpg binding protein 0.0053 0.0028 0.0028
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0003 0.0003
Toxoplasma gondii aminopeptidase n, putative 0.0311 0.0242 0.0347
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0311 0.0242 0.0242
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Schistosoma mansoni intermediate filament proteins 0.0033 0.0011 0.0011
Onchocerca volvulus 0.0022 0.0003 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0055 0.0054
Loa Loa (eye worm) thioredoxin reductase 0.0045 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0311 0.0242 0.0242
Onchocerca volvulus 0.0031 0.001 0.0031
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0012 0.0011
Loa Loa (eye worm) glutathione reductase 0.0045 0.0022 0.0022
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0003 0.0002
Brugia malayi RNA recognition motif domain containing protein 0.0171 0.0126 0.0126
Echinococcus granulosus replication factor c subunit 1 0.0023 0.0004 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0003 0.0002
Onchocerca volvulus 0.01 0.0067 0.0268
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0023 0.0004 0.0087
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0022 0.0031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0085 0.0055 0.0054
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0017 0.0016
Echinococcus multilocularis g-protein coupled receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.015 0.0108 0.0108
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0013 0.0013
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0018 0.0017
Onchocerca volvulus Protein ultraspiracle homolog 0.0085 0.0055 0.0215
Brugia malayi nuclear receptor NHR-67 0.004 0.0018 0.0017
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.015 0.0108 0.0108
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0311 0.0242 0.0242
Brugia malayi DKFZp564C0469 protein 0.0023 0.0004 0.0003
Onchocerca volvulus 0.0035 0.0013 0.0046
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0023 0.0023
Brugia malayi hypothetical protein 0.0031 0.001 0.001
Leishmania major tagatose-6-phosphate kinase-like protein 0.0189 0.0141 0.0202
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0034 0.0013 0.0012
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0044 0.0021 0.0021
Brugia malayi Cytochrome P450 family protein 0.0064 0.0038 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0268 0.0206 0.0206
Echinococcus granulosus carbonic anhydrase 0.0033 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Schistosoma mansoni cellular tumor antigen P53 0.0126 0.0089 0.0088
Schistosoma mansoni aryl hydrocarbon receptor 0.0042 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0044 0.0021 0.0021
Loa Loa (eye worm) follicle stimulating hormone receptor 0.015 0.0108 0.0108
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.015 0.0108 0.0108
Trypanosoma brucei trypanothione reductase 0.0045 0.0022 0.0031
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0095 0.0063 0.0063
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0104 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Onchocerca volvulus 0.015 0.0108 0.0436
Leishmania major adenosine kinase-like protein 0.0189 0.0141 0.0202
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0075 0.0046 0.0046
Leishmania major mitochondrial DNA polymerase beta 0.0583 0.0467 0.067
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Leishmania major DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Entamoeba histolytica beta-N-acetylhexosaminidase, putative 0.0348 0.0272 0.7403
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.003 0.0029
Leishmania major cathepsin L-like protease 0.0065 0.0039 0.0055
Echinococcus multilocularis sodium:hydrogen exchanger 0.0039 0.0016 0.0016
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0024 0.0024
Echinococcus multilocularis fmrfamide receptor 0.015 0.0108 0.0108
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.0674 0.0674
Onchocerca volvulus 0.015 0.0108 0.0436
Echinococcus multilocularis tachykinin peptides receptor 99D 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Schistosoma mansoni cpg binding protein 0.0053 0.0028 0.0028
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0003 0.0003
Schistosoma mansoni carbonic anhydrase 0.0033 0.0011 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0033
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0115 0.0079 0.0079
Schistosoma mansoni thyroid hormone receptor 0.0085 0.0055 0.0054
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0311 0.0242 0.2095
Echinococcus granulosus carbonic anhydrase 0.0033 0.0011 0.0011
Schistosoma mansoni chromosome transmission fidelity factor 0.0023 0.0004 0.0003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0021 0.003
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0035 0.0035
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0077 0.0048 0.0048
Schistosoma mansoni biogenic amine receptor 0.015 0.0108 0.0108
Echinococcus multilocularis expressed conserved protein 0.0228 0.0173 0.0173
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Trichomonas vaginalis guanylate cyclase, putative 0.0021 0.0002 0.0011
Echinococcus multilocularis thioredoxin glutathione reductase 0.0045 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0131 0.0092 0.0092
Trichomonas vaginalis ribokinase, putative 0.0189 0.0141 0.1218
Brugia malayi mbt repeat family protein 0.0048 0.0024 0.0024
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0311 0.0242 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0035 0.005
Trypanosoma brucei oxidoreductase-like protein 0.0024 0.0005 0.0006
Giardia lamblia Replication factor C, subunit 1 0.0023 0.0004 0.0087
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0011
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0039 0.0016 0.0058
Schistosoma mansoni hypothetical protein 0.015 0.0108 0.0108
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.006 0.006
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0003 0.0003
Schistosoma mansoni dihydrofolate reductase 1.2103 1 1
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0011 0.0011
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.015 0.0108 0.0108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.015 0.0108 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0007 0.0009
Mycobacterium ulcerans dihydropteroate synthase 1 FolP1 0.0092 0.0061 0.0061
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.004 0.0018 0.0017
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0023 0.0199
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0039 0.0016 0.0058
Onchocerca volvulus 0.004 0.0018 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0044 0.0021 0.0021
Echinococcus multilocularis G protein coupled receptor 139 0.015 0.0108 0.0108
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0064 0.0038 0.0037
Loa Loa (eye worm) matrixin family protein 0.0037 0.0015 0.0014
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.01 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0023 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0044 0.0021 0.0021
Schistosoma mansoni microsomal glutathione s-transferase 0.1264 0.103 0.103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0085 0.0055 0.0054
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0023 0.0004 0.0028
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Mycobacterium tuberculosis Carboxylesterase LipT 0.01 0.0067 0.0067
Echinococcus multilocularis para nitrobenzyl esterase 0.01 0.0067 0.0067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0311 0.0242 0.0347
Loa Loa (eye worm) neuropeptide F receptor 0.015 0.0108 0.0108
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0075 0.0046 0.0046
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0017 0.0016
Echinococcus granulosus somatostatin receptor 0.015 0.0108 0.0108
Echinococcus granulosus tachykinin peptides receptor 99D 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0031 0.003
Echinococcus multilocularis BC026374 protein (S09 family) 0.01 0.0067 0.0067
Echinococcus multilocularis fmrfamide receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) DR-78 0.004 0.0018 0.0017
Echinococcus granulosus adenosine kinase 0.1658 0.1356 0.1356
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0311 0.0242 0.0347
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.0144 0.0144
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Brugia malayi Probable isocitrate dehydrogenase 0.0095 0.0063 0.0063
Echinococcus multilocularis serotonin receptor 0.0268 0.0206 0.0206
Echinococcus multilocularis orexin receptor type 2 0.015 0.0108 0.0108
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0034 0.0048
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0311 0.0242 0.0347
Echinococcus granulosus neuroligin 0.01 0.0067 0.0067
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0021 0.0002 0.0002
Onchocerca volvulus 0.015 0.0108 0.0436
Schistosoma mansoni opsin-like receptor 0.015 0.0108 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Echinococcus granulosus neuropeptide receptor 0.015 0.0108 0.0108
Mycobacterium ulcerans thymidylate synthase 0.2969 0.2441 0.2441
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Brugia malayi ADAM-TS Spacer 1 family protein 0.0031 0.001 0.001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.005 0.005
Brugia malayi bHLH-PAS transcription factor 0.0021 0.0002 0.0002
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0003 0.0003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0085 0.0055 0.0054
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0077 0.0048 0.0048
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0044 0.0021 0.003
Brugia malayi Dopamine receptor protein 1 0.015 0.0108 0.0108
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0003 0.0002
Echinococcus granulosus carbonic anhydrase 0.0033 0.0011 0.0011
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0039 0.0016 0.0016
Brugia malayi topoisomerase 0.0023 0.0004 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0007 0.0009
Leishmania major methionine synthase, putative 0.0034 0.0013 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.015 0.0108 0.0108
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0131 0.0092 0.2508
Brugia malayi Glycosyl hydrolase family 20, catalytic domain containing protein 0.0081 0.0051 0.0051
Brugia malayi Nuclear hormone receptor E75 0.004 0.0018 0.0017
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0189 0.0141 0.014
Echinococcus granulosus lamin 0.0033 0.0011 0.0011
Mycobacterium leprae Probable dihydropteroate synthase 1 FolP1 (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate dipyrophosphorylase 1) 0.0092 0.0061 0.0059
Onchocerca volvulus 0.015 0.0108 0.0436
Echinococcus granulosus cytochrome P450 2K1 0.0044 0.0021 0.0021
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0171 0.0126 0.0126
Echinococcus multilocularis serotonin receptor 0.0268 0.0206 0.0206
Plasmodium falciparum replication factor C subunit 1, putative 0.0023 0.0004 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0044 0.0381
Echinococcus granulosus Protein patched homolog 1 0.0104 0.0071 0.007
Echinococcus multilocularis adenosine kinase 0.1658 0.1356 0.1356
Echinococcus granulosus dihydrofolate reductase 1.2103 1 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.01 0.0068 0.0067
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0013 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Echinococcus granulosus microtubule associated protein 2 0.0833 0.0674 0.0674
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.015 0.0108 0.0108
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0115 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0189 0.0141 0.014
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0045 0.0022 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0103 0.0147
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0095 0.0063 0.0062
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0039 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0243 0.0185 0.5036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Schistosoma mansoni hypothetical protein 0.01 0.0068 0.0067
Brugia malayi latrophilin 2 splice variant baaae 0.0172 0.0126 0.0126
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0034 0.0013 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0021 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Leishmania major cytochrome p450-like protein 0.0044 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0022 0.0021
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.003 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) glycosyl hydrolase family 20 0.0348 0.0272 0.0272
Plasmodium falciparum thioredoxin reductase 0.0045 0.0022 0.0031
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0013 0.0017
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0143 0.0102 0.0102
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0055 0.0054
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0075 0.0046 0.0046
Brugia malayi nuclear receptor RXR 0.004 0.0018 0.0017
Leishmania major hypothetical protein, conserved 0.0034 0.0013 0.0018
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0013 0.0019
Mycobacterium ulcerans B12-dependent methionine synthase 0.0034 0.0013 0.0012
Entamoeba histolytica fructokinase, putative 0.0189 0.0141 0.382
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0085 0.0055 0.0054
Brugia malayi hypothetical protein 0.0044 0.0021 0.002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0247 0.0189 0.0188
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0033 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0085 0.0055 0.0054
Brugia malayi Inositol-1 0.0034 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Echinococcus granulosus g protein coupled receptor 0.015 0.0108 0.0108
Echinococcus multilocularis sodium:hydrogen exchanger 0.0039 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0251 0.0192 0.0192
Leishmania major oxidoreductase-like protein 0.0024 0.0005 0.0006
Echinococcus multilocularis protein dispatched 1 0.0119 0.0083 0.0083
Leishmania major protein kinase, putative 0.0031 0.001 0.0014
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0079 0.005 0.005
Echinococcus granulosus carbonic anhydrase II 0.0143 0.0102 0.0102
Loa Loa (eye worm) NHE-3 0.0039 0.0016 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0261 0.0201 0.02
Schistosoma mansoni hypothetical protein 0.08 0.0646 0.0646
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0031 0.001 0.001
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0075 0.0046 0.0046
Brugia malayi CXXC zinc finger family protein 0.005 0.0026 0.0025
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0034 0.0013 0.0012
Schistosoma mansoni nuclear hormone receptor 0.004 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Schistosoma mansoni neuropeptide f receptor 76f 0.015 0.0108 0.0108
Loa Loa (eye worm) RNA binding protein 0.0171 0.0126 0.0126
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0238 0.0182 0.0181
Onchocerca volvulus 0.0024 0.0005 0.001
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0085 0.0055 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Leishmania major trypanothione reductase 0.0045 0.0022 0.0031
Brugia malayi nuclear hormone receptor family member nhr-6 0.004 0.0018 0.0017
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0003 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0046 0.0045
Schistosoma mansoni cpg binding protein 0.005 0.0026 0.0025
Echinococcus granulosus g protein coupled receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0052 0.0028 0.0027
Brugia malayi MH2 domain containing protein 0.0282 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0311 0.0242 0.0242
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0082 0.0052 0.0075
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0044 0.0381
Brugia malayi gonadotropin-releasing hormone receptor 2 0.015 0.0108 0.0108
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0017 0.0024
Brugia malayi Niemann-Pick C1 protein precursor 0.0243 0.0185 0.0185
Trichomonas vaginalis adenylate cyclase, putative 0.0021 0.0002 0.0011
Brugia malayi Tachykinin-like peptides receptor 99D 0.015 0.0108 0.0108
Echinococcus multilocularis musashi 0.0033 0.0011 0.0011
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0003 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0171 0.0126 0.0126
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0085 0.0055 0.0054
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0131 0.0092 0.0092
Echinococcus multilocularis lamin 0.0033 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0013 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0013 0.0018
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0095 0.0063 0.0063
Echinococcus granulosus serotonin receptor 0.015 0.0108 0.0108
Brugia malayi Cytochrome P450 family protein 0.0044 0.0021 0.0021
Echinococcus granulosus Niemann Pick C1 protein 0.0347 0.0272 0.0271
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0045 0.0022 0.0021
Brugia malayi glutathione reductase 0.0045 0.0022 0.0022
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0115 0.0079 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0103 0.0147
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0044 0.0021 0.0021
Loa Loa (eye worm) neuropeptide F receptor 0.015 0.0108 0.0108
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0583 0.0467 0.067
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0031 0.001 0.001
Brugia malayi hypothetical protein 0.1412 0.1153 0.1153
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.001 0.001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0075 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0045 0.0022 0.0021
Plasmodium vivax thioredoxin reductase, putative 0.0045 0.0022 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Trichomonas vaginalis ribokinase, putative 0.0189 0.0141 0.1218
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0035 0.0035
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.0038 0.0054
Giardia lamblia DINP protein human, muc B family 0.0039 0.0017 0.0446
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0013 0.0019
Loa Loa (eye worm) isocitrate dehydrogenase 0.0785 0.0634 0.0634
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.1412 0.1153 0.1655
Echinococcus multilocularis GPCR, family 2 0.0079 0.005 0.005
Entamoeba histolytica hypothetical protein 0.0261 0.0201 0.5452
Toxoplasma gondii hypothetical protein 0.0033 0.0011 0.0016
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0024 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) TATA binding protein associated factor 0.0311 0.0242 0.0242
Plasmodium vivax hydroxymethylpterin pyrophosphokinase-dihydropteroate synthetase, putative 0.0157 0.0114 0.0164
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Brugia malayi G-protein coupled receptor 0.015 0.0108 0.0108
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0021 0.0002 0.0011
Mycobacterium ulcerans dihydrofolate reductase DfrA 1.2103 1 1
Echinococcus multilocularis sex peptide receptor 0.015 0.0108 0.0108
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.01 0.0067 0.0067
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0011 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0017 0.0016
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0311 0.0242 0.0347
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0044 0.0021 0.003
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.0038 0.0054
Trypanosoma brucei DNA polymerase eta, putative 0.0064 0.0037 0.0053
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0003 0.0003
Brugia malayi mbt repeat family protein 0.0048 0.0024 0.0024
Echinococcus granulosus neuropeptide Y receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0045 0.0022 0.0021
Echinococcus granulosus inositol monophosphatase 1 0.0034 0.0013 0.0012
Trypanosoma brucei unspecified product 0.0027 0.0007 0.0009
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0311 0.0242 0.0347
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0044 0.0021 0.0021
Loa Loa (eye worm) acetylcholinesterase 1 0.0594 0.0476 0.0476
Echinococcus granulosus cpg binding protein 0.0053 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0056 0.0031 0.003
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0024 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0044 0.0021 0.0021
Echinococcus multilocularis dro:myosuppressin receptor 0.015 0.0108 0.0108
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0045 0.0022 0.0021
Echinococcus multilocularis aminopeptidase N 0.0311 0.0242 0.0242
Loa Loa (eye worm) inositol-1 0.0034 0.0013 0.0012
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0785 0.0634 0.091
Brugia malayi Glycosyl hydrolase family 20, catalytic domain containing protein 0.0081 0.0051 0.0051
Chlamydia trachomatis dihydrofolate reductase 1.2103 1 1
Echinococcus granulosus microsomal glutathione S transferase 3 0.1264 0.103 0.103
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.8434 0.6964 1
Brugia malayi nuclear hormone receptor 0.0085 0.0055 0.0054
Mycobacterium ulcerans aminopeptidase N PepN 0.0311 0.0242 0.0242
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0031 0.001 0.001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0785 0.0634 0.0634
Brugia malayi hypothetical protein 0.0311 0.0242 0.0242
Brugia malayi nuclear receptor NHR-88 0.0085 0.0055 0.0054
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0055 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.8434 0.6964 1
Onchocerca volvulus Hexosaminidase D homolog 0.0081 0.0051 0.0201
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0046 0.0046
Brugia malayi Peptidase family M1 containing protein 0.0311 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0002 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0004 0.0005
Loa Loa (eye worm) nuclear receptor NHR-67 0.004 0.0018 0.0017
Brugia malayi Peptidase family M1 containing protein 0.0311 0.0242 0.0242
Echinococcus granulosus neuropeptide FF receptor 2 0.015 0.0108 0.0108
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0003 0.0002
Echinococcus granulosus carboxylesterase 5A 0.0594 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.0056 0.0031 0.003
Schistosoma mansoni DNA ligase IV 0.0023 0.0004 0.0003
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Schistosoma mansoni beta-hexosaminidase B 0.0348 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0095 0.0063 0.0063
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0785 0.0634 0.091
Trichomonas vaginalis replication factor C large subunit, putative 0.0023 0.0004 0.0028
Schistosoma mansoni hypothetical protein 0.0123 0.0086 0.0086
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0021 0.0002 0.0002
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.015 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0261 0.0201 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0013 0.0112
Schistosoma mansoni aminopeptidase A (M01 family) 0.0311 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Entamoeba histolytica aminopeptidase, putative 0.0311 0.0242 0.6574
Onchocerca volvulus 0.0189 0.0141 0.0568
Toxoplasma gondii cytochrome p450 superfamily protein 0.0044 0.0021 0.003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0034 0.0013 0.1934
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0039 0.0016 0.0016
Loa Loa (eye worm) CXXC zinc finger family protein 0.005 0.0026 0.0025
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0044 0.0021 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0044 0.0021 0.0021
Trypanosoma cruzi adenosine kinase, putative 0.1658 0.1356 0.1947
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Onchocerca volvulus 0.015 0.0108 0.0436
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0311 0.0242 0.2095
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.2969 0.2441 0.2441
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Onchocerca volvulus 0.004 0.0018 0.0063
Onchocerca volvulus 0.0033 0.0011 0.0038
Toxoplasma gondii isocitrate dehydrogenase 0.0785 0.0634 0.091
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.015 0.0108 0.0108
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0013 0.0018
Echinococcus multilocularis beta hexosaminidase subunit beta 0.0348 0.0272 0.0272
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.01 0.0067 0.0582
Echinococcus granulosus G protein coupled receptor 139 0.015 0.0108 0.0108
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0022 0.0021
Plasmodium falciparum glutathione reductase 0.0045 0.0022 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0046 0.0046
Brugia malayi Dopamine receptor 0.015 0.0108 0.0108
Echinococcus granulosus dna polymerase eta 0.0064 0.0037 0.0037
Onchocerca volvulus 0.005 0.0026 0.0096
Brugia malayi TAR-binding protein 0.0171 0.0126 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0013 0.0013
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.01 0.0067 0.0067
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.01 0.0067 0.0067
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0583 0.0467 0.067
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0463 0.0368 0.3187
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0143 0.0103 0.0887
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Trichomonas vaginalis beta-hexosaminidase, putative 0.0217 0.0164 0.1422
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0024 0.0024
Echinococcus granulosus ecdysone induced protein 78C 0.0085 0.0055 0.0054
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0044 0.0021 0.0021
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 1.2103 1 1
Mycobacterium ulcerans hypothetical protein 0.0307 0.0239 0.0238
Echinococcus granulosus beta hexosaminidase subunit alpha 0.0217 0.0164 0.0164
Onchocerca volvulus 0.015 0.0108 0.0436
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.015 0.0108 0.0108
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0311 0.0242 0.0347
Brugia malayi hypoxia-induced factor 1 0.0089 0.0058 0.0058
Brugia malayi RNA binding protein 0.0171 0.0126 0.0126
Onchocerca volvulus 0.0155 0.0113 0.0453
Loa Loa (eye worm) cytochrome P450 family protein 0.0086 0.0056 0.0055
Brugia malayi Matrixin family protein 0.0037 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0011
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.1264 0.103 0.103
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0004 0.0005
Mycobacterium tuberculosis Adenosine kinase 0.0189 0.0141 0.0141
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0003 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0004 0.0028
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0276 0.0213 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0004 0.0028
Echinococcus granulosus sodium:hydrogen exchanger 0.0039 0.0016 0.0016
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0021 0.0002 0.0002
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0189 0.0141 0.382
Echinococcus multilocularis sterol regulatory element binding protein 0.0104 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0104 0.0071 0.007
Leishmania major hypothetical protein, conserved 0.0044 0.0021 0.0029
Echinococcus multilocularis transcription factor btf3 0.0035 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0189 0.0141 0.1218
Echinococcus multilocularis nibrin 0.0023 0.0004 0.0003
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0047 0.0023 0.0623
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0044 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.8434 0.6964 1
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.032 0.025 0.025
Brugia malayi hypothetical protein 0.01 0.0067 0.0067
Echinococcus multilocularis protein patched 0.0104 0.0071 0.007
Schistosoma mansoni neuropeptide F-like receptor 0.015 0.0108 0.0108
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0023 0.0004 0.0002
Onchocerca volvulus 0.0021 0.0002 0.0000013134
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0463 0.0368 0.3187
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0039 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0004 0.0028
Echinococcus granulosus aryl hydrocarbon receptor 0.0052 0.0028 0.0027
Loa Loa (eye worm) cytochrome P450 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0095 0.0063 0.0063
Brugia malayi GnHR receptor homolog 0.015 0.0108 0.0108
Schistosoma mansoni unc-13 (munc13) 0.0095 0.0063 0.0063
Onchocerca volvulus 0.015 0.0108 0.0436
Loa Loa (eye worm) aminopeptidase N 0.0311 0.0242 0.0242
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0024 0.0005 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0126 0.0089 0.0088
Schistosoma mansoni opsin-like receptor 0.015 0.0108 0.0108
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.005 0.005
Onchocerca volvulus 0.0271 0.0209 0.0847
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0037 0.0037
Onchocerca volvulus 0.015 0.0108 0.0436
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0031 0.001 0.001
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.01 0.0067 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Loa Loa (eye worm) hypothetical protein 0.0268 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Brugia malayi hypothetical protein 0.0603 0.0483 0.0483
Chlamydia trachomatis bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase 0.0157 0.0114 0.0113
Brugia malayi CHE-14 protein 0.0104 0.0071 0.007
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0243 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0002
Echinococcus granulosus fmrfamide receptor 0.015 0.0108 0.0108
Echinococcus granulosus ribokinase 0.0189 0.0141 0.014
Trypanosoma brucei unspecified product 0.0027 0.0007 0.0009
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0785 0.0634 0.091
Onchocerca volvulus 0.1469 0.12 0.4911
Trichomonas vaginalis beta-hexosaminidase, putative 0.0081 0.0051 0.0441
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0054 0.0054
Echinococcus multilocularis dnaJ subfamily B 0.0708 0.057 0.057
Mycobacterium ulcerans hypothetical protein 0.0075 0.0046 0.0046
Brugia malayi Ribokinase 0.0189 0.0141 0.014
Echinococcus multilocularis serotonin transporter 0.0059 0.0033 0.0033
Schistosoma mansoni nuclear receptor 0.004 0.0018 0.0017
Echinococcus multilocularis g protein coupled receptor 0.015 0.0108 0.0108
Echinococcus multilocularis carbonic anhydrase II 0.0143 0.0102 0.0102
Trypanosoma cruzi adenosine kinase, putative 0.0189 0.0141 0.0202
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0018 0.0017
Loa Loa (eye worm) nuclear receptor nhr-7B 0.004 0.0018 0.0017
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.015 0.0108 0.0108
Echinococcus multilocularis lamin dm0 0.0033 0.0011 0.0011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0023 0.0023
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0044 0.0021 0.003
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.015 0.0108 0.0108
Echinococcus granulosus sterol regulatory element binding protein 0.0104 0.0071 0.007
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0005 0.0005
Brugia malayi neuropeptide F receptor 0.015 0.0108 0.0108
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0024 0.0005 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis ribokinase 0.0189 0.0141 0.014
Echinococcus multilocularis neuroligin 0.01 0.0067 0.0067
Schistosoma mansoni peptide (allatostatin)-like receptor 0.015 0.0108 0.0108
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0017 0.0142
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0785 0.0634 0.0634
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0044 0.0021 0.0021
Trypanosoma brucei unspecified product 0.0039 0.0017 0.0024
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0039 0.0016 0.0016
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0311 0.0242 0.0347
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Echinococcus granulosus ubiquitin specific protease 41 0.0047 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Schistosoma mansoni patched 1 0.0104 0.0071 0.007
Brugia malayi Cytochrome P450 family protein 0.0064 0.0038 0.0037
Brugia malayi Carboxylesterase family protein 0.01 0.0067 0.0067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0013 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0046 0.0046
Schistosoma mansoni acetylcholinesterase 0.01 0.0067 0.0067
Echinococcus granulosus g-protein coupled receptor 0.015 0.0108 0.0108
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0189 0.0141 0.0141
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0003 0.0003
Brugia malayi Serotonin receptor 0.015 0.0108 0.0108
Schistosoma mansoni steroid hormone receptor ad4bp 0.0085 0.0055 0.0054
Echinococcus multilocularis tar DNA binding protein 0.0171 0.0126 0.0126
Echinococcus multilocularis Niemann Pick C1 protein 0.0243 0.0185 0.0185
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.005 0.005
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0003 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0044 0.0021 0.0021
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.004 0.0018 0.0017
Onchocerca volvulus 0.015 0.0108 0.0436
Schistosoma mansoni ribokinase 0.0189 0.0141 0.014
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.006 0.006
Trichomonas vaginalis inositol monophosphatase, putative 0.0034 0.0013 0.0106
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0311 0.0242 0.0347
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0022 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0085 0.0055 0.0054
Loa Loa (eye worm) MBCTL1 0.0055 0.003 0.0029
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0013 0.0352
Treponema pallidum DNA ligase (lig) 0.0023 0.0004 0.0983
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Echinococcus granulosus g protein coupled receptor 0.015 0.0108 0.0108
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0 0.0000094845
Loa Loa (eye worm) leukotriene A4 hydrolase 0.5857 0.4831 0.4831
Loa Loa (eye worm) MH2 domain-containing protein 0.0282 0.0217 0.0217
Chlamydia trachomatis DNA ligase 0.0023 0.0004 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.0044 0.0021 0.0029
Brugia malayi Peptidase family M1 containing protein 0.0311 0.0242 0.0242
Loa Loa (eye worm) carboxylesterase 0.01 0.0067 0.0067
Echinococcus multilocularis allatostatin A receptor 0.015 0.0108 0.0108
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0077 0.0048 0.0048
Echinococcus granulosus peptide allatostatin:somatostatin 0.015 0.0108 0.0108
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0035 0.0035
Echinococcus multilocularis carboxylesterase 5A 0.0594 0.0476 0.0476
Schistosoma mansoni cytochrome P450 0.0044 0.0021 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0007 0.0009
Schistosoma mansoni neuroligin 3 (S09 family) 0.01 0.0067 0.0067
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0013 0.0106
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0311 0.0242 0.0242
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0045 0.0022 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0085 0.0055 0.0054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.1658 0.1356 0.1356
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0028 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0171 0.0126 0.0126
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Toxoplasma gondii isocitrate dehydrogenase 0.0785 0.0634 0.091
Plasmodium falciparum ataxin-2 like protein, putative 0.0044 0.0021 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Entamoeba histolytica acyl-coA synthetase, putative 0.0075 0.0046 0.1246
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0143 0.0102 0.0102
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0276 0.0213 0.0305
Onchocerca volvulus 0.0052 0.0027 0.0103
Echinococcus multilocularis neuropeptide receptor 0.015 0.0108 0.0108
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0044 0.0021 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0251 0.0192 0.0192
Schistosoma mansoni adenosine kinase 0.1658 0.1356 0.1356
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0044 0.0021 0.0021
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.015 0.0108 0.0108
Onchocerca volvulus 0.0022 0.0003 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0024 0.009
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0034 0.0013 0.0017
Onchocerca volvulus 0.015 0.0108 0.0436
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0039 0.0055
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0463 0.0368 0.3187
Brugia malayi Dihydrofolate reductase 1.2103 1 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0021 0.0002 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0085 0.0055 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.015 0.0108 0.0108
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.015 0.0108 0.0108
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0018 0.0063
Schistosoma mansoni survival motor neuron protein 0.0123 0.0086 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0044 0.0021 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0785 0.0634 0.0634
Mycobacterium tuberculosis Dihydropteroate synthase 2 FolP2 (DHPS 2) (dihydropteroate pyrophosphorylase 2) 0.0034 0.0013 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0028 0.0028
Schistosoma mansoni alpha-1 adrenergic receptor 0.015 0.0108 0.0108
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0017 0.0142
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0143 0.0102 0.0102
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0023 0.0004 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0046 0.0046
Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 0.0157 0.0114 0.0164
Brugia malayi Nuclear hormone receptor E75 0.004 0.0018 0.0017
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.0192 0.0192
Echinococcus granulosus neuropeptides capa receptor 0.015 0.0108 0.0108
Schistosoma mansoni lamin 0.0033 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0085 0.0055 0.0054
Schistosoma mansoni amine GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis g protein coupled receptor 0.015 0.0108 0.0108
Brugia malayi hypothetical protein 0.0045 0.0022 0.0021
Onchocerca volvulus 0.015 0.0108 0.0436
Echinococcus granulosus FTZ F1 alpha 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0171 0.0126 0.0126
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0034 0.0013 0.0331
Onchocerca volvulus 0.0022 0.0003 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0047 0.0023 0.0023
Brugia malayi Isocitrate dehydrogenase 0.0785 0.0634 0.0634
Brugia malayi Latrophilin receptor protein 2 0.0079 0.005 0.005
Onchocerca volvulus 0.0311 0.0242 0.0983
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0039 0.0016 0.0016
Schistosoma mansoni isocitrate dehydrogenase 0.0095 0.0063 0.0063
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0463 0.0368 0.0367
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.015 0.0108 0.0108
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0023 0.0623
Schistosoma mansoni hypothetical protein 0.0021 0.0002 0.0002
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.8434 0.6964 1
Onchocerca volvulus 0.015 0.0108 0.0436
Echinococcus granulosus 7TM GPCR rhodopsin 0.015 0.0108 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0085 0.0055 0.0054
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0085 0.0055 0.0054
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0085 0.0055 0.0215
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0002 0.0002
Echinococcus granulosus serotonin transporter 0.0059 0.0033 0.0033
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0021 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0046 0.0066
Trypanosoma brucei carbonic anhydrase-like protein 0.0143 0.0102 0.0147
Mycobacterium ulcerans aminopeptidase N PepN 0.0311 0.0242 0.0242
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0189 0.0141 0.014
Mycobacterium ulcerans carboxylesterase, LipT 0.01 0.0067 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0044 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0172 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0296 0.0229 0.0229
Schistosoma mansoni BC026374 protein (S09 family) 0.01 0.0067 0.0067
Plasmodium falciparum carbonic anhydrase 0.0033 0.0011 0.0016
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.001 0.001
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0189 0.0141 0.014
Echinococcus granulosus allatostatin A receptor 0.015 0.0108 0.0108
Brugia malayi Steroid receptor seven-up type 2 0.0085 0.0055 0.0054
Echinococcus multilocularis neuropeptide s receptor 0.0705 0.0568 0.0568
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0035 0.0035
Loa Loa (eye worm) oxidoreductase 0.0022 0.0003 0.0002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0 0.0000094845
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0136 0.0097 0.0138
Echinococcus multilocularis dna polymerase eta 0.0064 0.0037 0.0037
Schistosoma mansoni transcription factor LCR-F1 0.0261 0.0201 0.02
Loa Loa (eye worm) hypothetical protein 0.0056 0.0031 0.003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.007 0.007
Leishmania major carbonic anhydrase-like protein 0.0143 0.0102 0.0147
Echinococcus multilocularis acetylcholinesterase 0.0594 0.0476 0.0476
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.0002 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.0268 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0003
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0011 0.0011
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0011 0.0011
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0011 0.0011
Schistosoma mansoni beta-hexosaminidase B 0.0348 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.015 0.0108 0.0108
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0005 0.0004
Onchocerca volvulus Putative pyridoxal kinase 0.0189 0.0141 0.0568
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0785 0.0634 0.0634
Echinococcus multilocularis somatostatin receptor 0.015 0.0108 0.0108
Entamoeba histolytica hypothetical protein 0.0261 0.0201 0.5452
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0044 0.0021 0.0021
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0085 0.0055 0.0054
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0131 0.0092 0.0092
Echinococcus granulosus lamin dm0 0.0033 0.0011 0.0011
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.015 0.0108 0.0108
Schistosoma mansoni adenoreceptor 0.015 0.0108 0.0108
Leishmania major cytochrome p450-like protein 0.0044 0.0021 0.003
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0128 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Echinococcus granulosus tm gpcr rhodopsin 0.015 0.0108 0.0108
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0261 0.0201 0.02
Onchocerca volvulus 0.0059 0.0033 0.0126
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0017 0.0024
Brugia malayi photoreceptor-specific nuclear receptor 0.0085 0.0055 0.0054
Schistosoma mansoni nuclear hormone receptor 0.004 0.0018 0.0017
Schistosoma mansoni opsin-like receptor 0.015 0.0108 0.0108
Toxoplasma gondii kinase, pfkB family protein 0.0189 0.0141 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0013 0.0018
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0044 0.0021 0.0021
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0003 0.0002
Schistosoma mansoni RAR-like nuclear receptor 0.0085 0.0055 0.0054
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0115 0.008 0.008
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0023 0.0004 0.0028
Loa Loa (eye worm) melatonin receptor type 1A 0.015 0.0108 0.0108
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0055 0.003 0.003
Echinococcus granulosus neuropeptides capa receptor 0.015 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0056 0.0031 0.003
Schistosoma mansoni coup transcription factor 0.0085 0.0055 0.0054
Brugia malayi hypothetical protein 0.2693 0.2213 0.2213
Brugia malayi beta-NAC-like protein 0.0035 0.0013 0.0013
Brugia malayi nuclear receptor RXR 0.0045 0.0022 0.0021
Brugia malayi G protein-coupled receptor 0.015 0.0108 0.0108
Echinococcus granulosus transcription factor btf3 0.0035 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0143 0.0102 0.0102
Entamoeba histolytica beta-N-acetylhexosaminidase, beta subunit 0.0348 0.0272 0.7403
Loa Loa (eye worm) hypothetical protein 0.0189 0.0141 0.014
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0013 0.0019
Trypanosoma brucei ribokinase, putative 0.0189 0.0141 0.0202
Echinococcus granulosus nibrin 0.0023 0.0004 0.0003
Brugia malayi Glycosyl hydrolase family 20, catalytic domain containing protein 0.0348 0.0272 0.0272
Leishmania major adenosine kinase, putative 0.1658 0.1356 0.1947
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0003 0.0002
Brugia malayi Pre-SET motif family protein 0.0238 0.0182 0.0181
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0039 0.0016 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0583 0.0467 0.067
Schistosoma mansoni myosin xvIII 0.015 0.0108 0.0108
Echinococcus granulosus aminopeptidase N 0.0311 0.0242 0.0242
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0013 0.0018
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0785 0.0634 0.091
Entamoeba histolytica beta-N-acetylhexosaminidase, putative 0.0348 0.0272 0.7403
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0003 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0017
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0003 0.0003
Plasmodium falciparum acyl-CoA synthetase 0.0056 0.0031 0.0043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0018 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0021 0.0002 0.0002
Echinococcus multilocularis aryl hydrocarbon receptor 0.0052 0.0028 0.0027
Brugia malayi hypothetical protein 0.0155 0.0113 0.0112
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.015 0.0108 0.0108
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0785 0.0634 0.091
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0095 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Loa Loa (eye worm) TAR-binding protein 0.0171 0.0126 0.0126
Echinococcus multilocularis biogenic amine (5HT) receptor 0.015 0.0108 0.0108
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0085 0.0055 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.015 0.0108 0.0108
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0046 0.0046
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0002 0.0011
Onchocerca volvulus 0.0085 0.0055 0.0215
Leishmania major putative PfkB family sugar kinase 0.0189 0.0141 0.0202
Schistosoma mansoni inositol monophosphatase 0.0034 0.0013 0.0012
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0003 0.0003
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0023 0.0004 0.0028
Schistosoma mansoni biogenic amine (5HT) receptor 0.015 0.0108 0.0108
Brugia malayi thymidylate synthase 0.2969 0.2441 0.2441
Onchocerca volvulus 0.01 0.0067 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0071 0.061
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0023 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.006 0.006
Brugia malayi conserved hypotetical protein 0.004 0.0018 0.0017
Brugia malayi steroid hormone receptor 0.0085 0.0055 0.0054
Entamoeba histolytica beta-N-acetylhexosaminidase, alpha subunit 0.0348 0.0272 0.7403
Onchocerca volvulus 0.015 0.0108 0.0436
Echinococcus multilocularis leukotriene A 4 hydrolase 0.5857 0.4831 0.4831
Schistosoma mansoni ap endonuclease 0.0019 0 0.0000094845
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0044 0.0021 0.0021
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0085 0.0055 0.0054
Onchocerca volvulus 0.0023 0.0004 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus thioredoxin glutathione reductase 0.0045 0.0022 0.0022
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.2969 0.2441 0.244
Schistosoma mansoni neuropeptide receptor 0.015 0.0108 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) G-protein coupled receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) TYRA-2 protein 0.015 0.0108 0.0108
Echinococcus multilocularis neuropeptide receptor 0.015 0.0108 0.0108
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0021 0.0002 0.0011
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0143 0.0102 0.0147
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0311 0.0242 0.0347
Brugia malayi hypothetical protein 0.0023 0.0004 0.0003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0081 0.0051 0.0051
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0095 0.0063 0.0063
Loa Loa (eye worm) carboxylesterase 0.01 0.0067 0.0067
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0311 0.0242 0.0347
Brugia malayi intermediate filament protein 0.0033 0.0011 0.0011
Trypanosoma brucei cytochrome P450, putative 0.0064 0.0038 0.0054
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0038 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0039 0.0055
Loa Loa (eye worm) carbonic anhydrase 3 0.0143 0.0102 0.0102
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.006 0.006
Echinococcus multilocularis microsomal glutathione S transferase 3 0.1264 0.103 0.103
Schistosoma mansoni biogenic amine (dopamine) receptor 0.015 0.0108 0.0108
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0085 0.0055 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0023 0.0004 0.0005
Leishmania major isocitrate dehydrogenase, putative 0.0095 0.0063 0.009
Toxoplasma gondii ATPase, AAA family protein 0.0023 0.0004 0.0005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0 0.0000094845
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0021 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Entamoeba histolytica tartrate dehydrogenase, putative 0.0095 0.0063 0.1713
Schistosoma mansoni single-minded 0.0042 0.0019 0.0019
Echinococcus multilocularis dihydrofolate reductase 1.2103 1 1
Echinococcus granulosus geminin 0.08 0.0646 0.0646
Echinococcus granulosus tm gpcr rhodopsin 0.015 0.0108 0.0108
Brugia malayi hypothetical protein 0.004 0.0018 0.0017
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.0144 0.0144
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Schistosoma mansoni nuclear receptor nhr-48 0.004 0.0018 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0085 0.0055 0.0054
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.007 0.007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.015 0.0108 0.0108
Onchocerca volvulus Protein cycle homolog 0.0031 0.001 0.0033
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0003 0.0001
Onchocerca volvulus 0.0126 0.0089 0.0355
Mycobacterium leprae PROBABLE DIHYDROPTEROATE SYNTHASE 2 FOLP2 (DHPS 2) (Dihydropteroate pyrophosphorylase 2) 0.0034 0.0013 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0044 0.0021 0.0021
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0018 0.0017
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.007 0.007
Loa Loa (eye worm) hypoxia-induced factor 1 0.0089 0.0058 0.0058
Mycobacterium leprae Probable adenosine kinase adk 0.0189 0.0141 0.0139
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0095 0.0063 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2001 0.164 0.164
Schistosoma mansoni amine GPCR 0.015 0.0108 0.0108
Brugia malayi Pre-SET motif family protein 0.0035 0.0013 0.0013
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Toxoplasma gondii aminopeptidase N, putative 0.0311 0.0242 0.0347
Leishmania major ribokinase, putative 0.0189 0.0141 0.0202
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0046 0.0046
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0085 0.0055 0.0054
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.01 0.0067 0.0067
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0035 0.0035
Onchocerca volvulus 0.0033 0.0011 0.0038
Schistosoma mansoni lamin 0.0033 0.0011 0.0011
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0085 0.0055 0.0054
Leishmania major tagatose-6-phosphate kinase-like protein 0.0189 0.0141 0.0202
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0594 0.0476 0.0476
Brugia malayi sulfakinin receptor protein 0.015 0.0108 0.0108
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0003 0.0002
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0038 0.0016 0.0016
Trypanosoma cruzi adenosine kinase, putative 0.1658 0.1356 0.1947
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0017 0.0016
Schistosoma mansoni biogenic amine receptor 0.015 0.0108 0.0108
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0023 0.0004 0.0005
Schistosoma mansoni neuropeptide F-like receptor 0.015 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0004 0.0028
Echinococcus multilocularis tumor protein p63 0.0861 0.0697 0.0697
Onchocerca volvulus 0.015 0.0108 0.0436
Brugia malayi nuclear hormone receptor 0.004 0.0018 0.0017
Echinococcus multilocularis acetylcholinesterase 0.0594 0.0476 0.0476
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0022 0.0021
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0044 0.0021 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0046 0.1246
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0115 0.0079 0.0079
Trypanosoma brucei adenosine kinase, putative 0.1658 0.1356 0.1947
Brugia malayi tailless protein 0.004 0.0018 0.0017
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0311 0.0242 0.0242
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.01 0.0067 0.0096
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0311 0.0242 0.0242
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.003 0.0029
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0013 0.0013
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0024 0.0005 0.0004
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0311 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0189 0.0141 0.382
Loa Loa (eye worm) nuclear hormone receptor 0.004 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.001
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0017 0.0016
Echinococcus granulosus beta hexosaminidase subunit beta 0.0348 0.0272 0.0272
Brugia malayi nuclear receptor NHR-88 0.004 0.0018 0.0017
Loa Loa (eye worm) CYP4Cod1 0.0064 0.0038 0.0037
Schistosoma mansoni hypothetical protein 0.08 0.0646 0.0646
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0023 0.0033
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0017 0.0024
Schistosoma mansoni DNA polymerase eta 0.0064 0.0037 0.0037
Brugia malayi hypothetical protein 0.0311 0.0242 0.0242
Onchocerca volvulus 0.0311 0.0242 0.0983
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.015 0.0108 0.0108
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0011 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0171 0.0126 0.0126
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0054 0.0054
Schistosoma mansoni multidrug resistance protein 0.0034 0.0013 0.0012
Brugia malayi hypothetical protein 0.0028 0.0008 0.0007
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0039 0.0016 0.0016
Brugia malayi ecdysteroid receptor 0.0085 0.0055 0.0054
Toxoplasma gondii hypothetical protein 0.0094 0.0062 0.0089
Mycobacterium ulcerans fructokinase, PfkB 0.0189 0.0141 0.014
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0143 0.0103 0.0887
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0017 0.0016
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.015 0.0108 0.0436
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0039 0.0055
Loa Loa (eye worm) hypothetical protein 0.0047 0.0023 0.0023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0003 0.0003
Brugia malayi Dopamine receptor protein 2 0.015 0.0108 0.0108
Loa Loa (eye worm) carboxylesterase 0.0594 0.0476 0.0476
Trypanosoma cruzi PAB1-binding protein , putative 0.0044 0.0021 0.0029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0155 0.0113 0.0112
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0003 0.0002
Schistosoma mansoni topbp1 0.0023 0.0004 0.0003
Echinococcus multilocularis Niemann Pick C1 protein 0.0347 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0011 0.0011
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.007 0.007
Brugia malayi Hemopexin family protein 0.0021 0.0002 0.0002
Leishmania major cytochrome p450-like protein 0.0064 0.0038 0.0054
Trichomonas vaginalis spcc417.12 protein, putative 0.01 0.0067 0.0582
Brugia malayi G-protein coupled receptor 0.015 0.0108 0.0108
Schistosoma mansoni biogenic amine receptor 0.015 0.0108 0.0108
Echinococcus granulosus Niemann Pick C1 protein 0.0243 0.0185 0.0185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.015 0.0108 0.0108
Echinococcus multilocularis neuropeptide Y receptor 0.015 0.0108 0.0108
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0046 0.1246
Loa Loa (eye worm) hypothetical protein 0.0141 0.0101 0.0101
Brugia malayi hypothetical protein 0.0141 0.0101 0.0101
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.015 0.0108 0.0108
Mycobacterium tuberculosis Dihydropteroate synthase 1 FolP (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate diphosphorylase 1) 0.0092 0.0061 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.006 0.006
Brugia malayi TATA binding protein associated factor 0.0311 0.0242 0.0242
Mycobacterium tuberculosis Probable oxidoreductase 0.0115 0.008 0.008
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0044 0.0021 0.0021
Trypanosoma cruzi FHA domain containing protein, putative 0.0023 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0075 0.0046 0.0046
Brugia malayi hypothetical protein 0.004 0.0018 0.0017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.005 0.005
Leishmania major pteridine reductase 1 0.0373 0.0293 0.0421
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0033
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0463 0.0368 1
Toxoplasma gondii MAPEG family protein 0.1264 0.103 0.1479
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0013 0.0017
Plasmodium vivax ataxin-2 like protein, putative 0.0044 0.0021 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0017 0.0024
Brugia malayi hypothetical protein 0.0045 0.0022 0.0021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0013 0.0106
Echinococcus granulosus nuclear receptor nhr 48 0.004 0.0018 0.0017
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0023 0.0004 0.0507
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0013 0.0112
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0055 0.0054
Echinococcus granulosus thyroid hormone receptor alpha 0.004 0.0018 0.0017
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0044 0.0021 0.0021
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0003 0.0002
Giardia lamblia Sodium/hydrogen exchanger 3 0.0039 0.0016 0.0435
Leishmania major cathepsin L-like protease 0.0065 0.0039 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0013 0.0013
Trypanosoma brucei aminopeptidase, putative 0.0311 0.0242 0.0347
Onchocerca volvulus 0.015 0.0108 0.0436
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0095 0.0063 0.0063
Echinococcus granulosus sodium:hydrogen exchanger 0.0039 0.0016 0.0016
Schistosoma mansoni biogenic amine (5HT) receptor 0.0268 0.0206 0.0206
Trypanosoma cruzi ribokinase, putative 0.0189 0.0141 0.0202
Trichomonas vaginalis ribokinase, putative 0.0189 0.0141 0.1218
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0311 0.0242 0.0347
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Loa Loa (eye worm) thymidylate synthase 0.2969 0.2441 0.2441
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.015 0.0108 0.0108
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0039 0.0055
Echinococcus multilocularis inositol monophosphatase 1 0.0034 0.0013 0.0012
Brugia malayi orphan nuclear receptor NR2E1 0.004 0.0018 0.0017
Schistosoma mansoni adenosine kinase 0.1658 0.1356 0.1356
Brugia malayi putative neuropeptide receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0039 0.0016 0.0016
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.8434 0.6964 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0172 0.0126 0.0126
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.015 0.0108 0.0108
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.01 0.0067 0.0067
Entamoeba histolytica ribokinase, putative 0.0189 0.0141 0.382
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0044 0.0021 0.0021
Trichomonas vaginalis beta-hexosaminidase, putative 0.0217 0.0164 0.1422
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.004 0.0018 0.0017
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0044 0.0021 0.0021
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.0192 0.0192
Plasmodium vivax glutathione reductase, putative 0.0045 0.0022 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0022 0.0021
Echinococcus granulosus acetylcholinesterase 0.0594 0.0476 0.0476
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.015 0.0108 0.0108
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0082 0.0052 0.0075
Trypanosoma brucei Aminopeptidase M1, putative 0.0311 0.0242 0.0347
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.003 0.001 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0085 0.0055 0.0054
Echinococcus multilocularis neuropeptide Y receptor 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0085 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0011
Brugia malayi AKH receptor 0.015 0.0108 0.0108
Brugia malayi Carboxylesterase family protein 0.0594 0.0476 0.0476
Brugia malayi Serotonin/octopamine receptor family protein 7 0.015 0.0108 0.0108
Trypanosoma cruzi Aminopeptidase M1, putative 0.0311 0.0242 0.0347
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0123 0.0086 0.0086
Schistosoma mansoni neuropeptide receptor 0.015 0.0108 0.0108
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0003 0.0001
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0003 0.0002
Trypanosoma brucei ribokinase, putative 0.0189 0.0141 0.0202
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.005 0.005
Brugia malayi Carboxylesterase family protein 0.01 0.0067 0.0067
Trypanosoma brucei MATE efflux family protein, putative 0.0034 0.0013 0.0018
Brugia malayi hypothetical protein 0.015 0.0108 0.0108
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0085 0.0055 0.0054
Schistosoma mansoni neuropeptide receptor 0.015 0.0108 0.0108
Leishmania major hypothetical protein, conserved 0.0143 0.0103 0.0147
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0011 0.0011
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0023 0.0033
Echinococcus granulosus dro:myosuppressin receptor 0.015 0.0108 0.0108
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.0674 0.0674
Echinococcus multilocularis rhodopsin orphan GPCR 0.015 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.015 0.0108 0.0108
Echinococcus granulosus GPCR family 2 0.0079 0.005 0.005
Loa Loa (eye worm) serotonin transporter b 0.0059 0.0033 0.0033
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0095 0.0063 0.0063
Leishmania major DNA polymerase eta, putative 0.0064 0.0037 0.0053
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0033 0.0011 0.0011
Echinococcus granulosus orexin receptor type 2 0.015 0.0108 0.0108

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) P 0 Antiinflammatory activity measured by using McKenzie-Stoughton human vasoconstrictor assay; Potent ChEMBL. 3783574

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.