Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0846 | 0.1215 |
Onchocerca volvulus | 0.0048 | 0.1189 | 0.2584 | |
Brugia malayi | Cytochrome P450 family protein | 0.0054 | 0.1394 | 0.2004 |
Echinococcus multilocularis | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0012 | 0.0075 | 0.0075 |
Plasmodium falciparum | exodeoxyribonuclease III, putative | 0.0012 | 0.0075 | 0.0494 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0958 | 0.0958 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.1513 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0058 | 0.1513 | 1 |
Echinococcus granulosus | CCR4 NOT transcription complex subunit 6 | 0.0012 | 0.0075 | 0.0075 |
Onchocerca volvulus | 0.0012 | 0.0075 | 0.0058 | |
Echinococcus granulosus | neutral sphingomyelinase | 0.0012 | 0.0075 | 0.0075 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0145 | 0.4198 | 0.6033 |
Trypanosoma cruzi | endonuclease/exonuclease/phosphatase, putative | 0.0012 | 0.0075 | 0.0494 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0378 | 0.2186 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0145 | 0.4198 | 0.4198 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0075 | 0.008 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0022 | 0.0024 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0049 | 0.0052 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0846 | 0.5587 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0011 | 0.0057 | 0.0057 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0058 | 0.1513 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0012 | 0.0077 | 0.0004 |
Echinococcus multilocularis | traf and tnf receptor associated protein | 0.0012 | 0.0075 | 0.0075 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0846 | 0.1215 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0049 | 0.0071 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0857 | 0.1232 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.103 | 0.6809 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0846 | 0.5357 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0012 | 0.0075 | 0.0075 |
Schistosoma mansoni | ocrl type II inositol 5-phosphatase | 0.0012 | 0.0075 | 0.0075 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0378 | 0.0378 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0049 | 0.0071 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0049 | 0.0049 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0058 | 0.1513 | 0.9629 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0853 | 0.0853 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0446 | 0.2837 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0028 | 0.0589 | 0.0589 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.2645 | 0.3801 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.008 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0607 | 0.3697 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0012 | 0.0077 | 0.0004 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0049 | 0.0049 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0049 | 0.0071 |
Leishmania major | inositol/phosphatidylinositol phosphatase, putative | 0.0012 | 0.0075 | 0.0476 |
Echinococcus granulosus | peregrin | 0.0032 | 0.0717 | 0.0717 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0846 | 0.1215 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0049 | 0.0049 |
Brugia malayi | hypothetical protein | 0.0112 | 0.3189 | 0.4583 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0233 | 0.696 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0846 | 0.0846 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0075 | 0.008 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.2524 | 0.3628 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0846 | 0.1119 |
Echinococcus granulosus | traf and tnf receptor associated protein | 0.0012 | 0.0075 | 0.0075 |
Leishmania major | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0476 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0022 | 0.0022 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0718 | 0.0718 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.371 | 0.3952 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0846 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0853 | 0.0908 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0846 | 0.514 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0011 | 0.0065 | 0.043 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0012 | 0.0077 | 0.0511 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0077 | 0.0492 |
Trypanosoma cruzi | mitochondrial protein 99, putative | 0.0012 | 0.0075 | 0.0494 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.337 | 0.359 |
Schistosoma mansoni | cytochrome P450 | 0.0012 | 0.0077 | 0.0077 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0853 | 0.1225 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0012 | 0.0077 | 0.0004 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.0065 | 0.043 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0378 | 0.0403 |
Trypanosoma cruzi | Inositol phosphosphingolipids phospholipase C | 0.0012 | 0.0075 | 0.0494 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0037 | 0.0857 | 0.4957 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0049 | 0.0071 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0049 | 0.0049 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0846 | 0.5587 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0077 | 0.0077 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0011 | 0.0057 | 0.0057 |
Onchocerca volvulus | 0.0037 | 0.0846 | 0.1805 | |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.1513 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.1572 | 0.1572 |
Plasmodium falciparum | DNase I-like protein, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0049 | 0.0071 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1247 | 0.1328 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0049 | 0.0071 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.3189 | 1 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0075 | 0.008 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0075 | 0.008 |
Trypanosoma brucei | DNA-(apurinic or apyrimidinic site) lyase, putative | 0.0012 | 0.0075 | 0.0494 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0049 | 0.0052 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0058 | 0.1513 | 0.9609 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1572 | 1 |
Echinococcus granulosus | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0012 | 0.0075 | 0.0075 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.103 | 0.5959 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0049 | 0.0071 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0012 | 0.0075 | 0.0494 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0846 | 0.1119 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0049 | 0.0049 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0077 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0037 | 0.0857 | 0.5663 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0846 | 0.5357 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.3189 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0617 | 0.357 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 1 | 1 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0037 | 0.0857 | 0.5663 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1572 | 0.1572 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0012 | 0.0077 | 0.0511 |
Trichomonas vaginalis | chaperonin, putative | 0.0028 | 0.0589 | 0.3577 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.371 | 0.371 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0846 | 0.514 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0846 | 0.5357 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.371 | 0.371 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0049 | 0.0049 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0049 | 0.0049 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0617 | 0.0617 |
Toxoplasma gondii | exonuclease III APE | 0.0058 | 0.1513 | 0.8753 |
Trypanosoma brucei | inositol/phosphatidylinositol phosphatase, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0049 | 0.0071 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0004 | 0.0004 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0037 | 0.0857 | 0.0857 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0378 | 0.2107 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.103 | 0.103 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0049 | 0.0049 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0028 | 0.0589 | 0.0589 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0012 | 0.0077 | 0.0004 |
Trypanosoma brucei | cytochrome P450, putative | 0.0012 | 0.0077 | 0.0511 |
Schistosoma mansoni | synaptojanin | 0.0012 | 0.0075 | 0.0075 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0378 | 0.0974 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0077 | 0.0111 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.3189 | 0.3189 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.371 | 0.371 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0012 | 0.0077 | 0.0004 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0077 | 0.0082 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0058 | 0.1513 | 0.1612 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0049 | 0.0071 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.1513 | 1 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0378 | 0.0543 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0058 | 0.1513 | 1 |
Schistosoma mansoni | nocturnin | 0.0012 | 0.0075 | 0.0075 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.1189 | 0.1189 |
Schistosoma mansoni | cript-related | 0.0012 | 0.0075 | 0.0075 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0846 | 0.514 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0378 | 0.2497 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0846 | 0.0901 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.6958 | 0.7412 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0049 | 0.0049 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0028 | 0.0589 | 0.3894 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.1572 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.103 | 0.5959 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0049 | 0.0049 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0049 | 0.0049 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.014 | 0.4072 | 0.4072 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0846 | 0.1119 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0077 | 0.0511 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0846 | 0.5357 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | hypothetical protein | 0.0233 | 0.6958 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0312 | 0.9387 | 0.9387 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0378 | 0.2405 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0607 | 0.0607 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.0717 | 0.0717 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0857 | 0.5663 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0846 | 0.0901 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.3189 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0049 | 0.0071 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.1561 | 0.1662 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.4461 | 0.4752 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0607 | 0.0607 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0607 | 0.4008 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0378 | 0.2497 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0012 | 0.0077 | 0.0492 |
Trypanosoma cruzi | mitochondrial protein 99, putative | 0.0012 | 0.0075 | 0.0494 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0012 | 0.0077 | 0.0004 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0012 | 0.0077 | 0.0004 |
Brugia malayi | CCR4 | 0.0012 | 0.0075 | 0.0107 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0617 | 0.0617 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0921 | 0.5879 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.371 | 0.5332 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1572 | 0.1572 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.1513 | 1 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0028 | 0.0589 | 0.3894 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.2645 | 0.2645 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0077 | 0.0082 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0069 | 0.1847 | 0.1847 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0718 | 0.1032 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0112 | 0.3189 | 0.3189 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0028 | 0.0589 | 0.375 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0145 | 0.4198 | 0.4198 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0049 | 0.0049 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1572 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0846 | 0.0901 |
Onchocerca volvulus | 0.0153 | 0.4461 | 1 | |
Loa Loa (eye worm) | CCR4-NOT transcription complex subunit 6 family protein | 0.0012 | 0.0075 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Plasmodium vivax | endonuclease/exonuclease/phosphatase domain containing protein | 0.0012 | 0.0075 | 0.0494 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.6958 | 0.6958 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0012 | 0.0077 | 0.0004 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0058 | 0.1513 | 0.2089 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.371 | 0.3952 |
Schistosoma mansoni | carbon catabolite repressor protein | 0.0012 | 0.0075 | 0.0075 |
Echinococcus multilocularis | geminin | 0.0331 | 1 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.6958 | 0.6958 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.1513 | 0.1513 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0049 | 0.0071 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0446 | 0.2946 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0012 | 0.0075 | 0.0494 |
Trypanosoma brucei | RNA editing exonuclease 2 | 0.0012 | 0.0075 | 0.0494 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0312 | 0.9387 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0049 | 0.0071 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.3189 | 1 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2524 | 0.2524 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0846 | 0.1215 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0028 | 0.0589 | 0.3577 |
Brugia malayi | cytochrome P450 | 0.0012 | 0.0077 | 0.0111 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0049 | 0.0049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0049 | 0.0071 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0012 | 0.0077 | 0.0447 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0846 | 0.0846 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0607 | 0.3509 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.1189 | 0.1189 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0049 | 0.0071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0049 | 0.0052 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0022 | 0.0022 |
Onchocerca volvulus | 0.0037 | 0.0846 | 0.1805 | |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0009 | 0.0004 | 0.0024 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0028 | 0.0589 | 0.3577 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0049 | 0.0049 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.1513 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0921 | 0.2716 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0446 | 0.2579 |
Leishmania major | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0476 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0012 | 0.0077 | 0.0004 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0065 | 0.1729 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0846 | 0.0901 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0049 | 0.0052 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1572 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0049 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0049 | 0.0071 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0846 | 0.489 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0776 | 0.0776 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.1572 | 0.909 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0853 | 0.0853 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.337 | 0.4843 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0049 | 0.0071 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.2645 | 0.2645 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0446 | 0.2579 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0846 | 0.5357 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0058 | 0.1513 | 0.1513 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0921 | 0.6082 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0012 | 0.0077 | 0.0004 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.371 | 0.3952 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0617 | 0.4079 |
Leishmania major | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0476 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0012 | 0.0077 | 0.0004 |
Leishmania major | inositol phosphosphingolipid phospholipase C-Like | 0.0012 | 0.0075 | 0.0476 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0054 | 0.1394 | 0.1485 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0607 | 0.1264 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0378 | 0.2107 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0012 | 0.0077 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2524 | 0.2524 |
Echinococcus multilocularis | CCR4 NOT transcription complex subunit 6 | 0.0012 | 0.0075 | 0.0075 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0776 | 0.0776 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0075 | 0.008 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0776 | 0.0776 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0846 | 0.1119 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0607 | 0.0872 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0857 | 0.5663 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0853 | 0.0853 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0617 | 0.4079 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Brugia malayi | AF-10 protein | 0.0009 | 0.0004 | 0.0005 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0077 | 0.0511 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0378 | 0.2497 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2524 | 0.2524 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0846 | 0.1119 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0028 | 0.0589 | 0.0628 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0857 | 0.5438 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.337 | 0.359 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0028 | 0.0589 | 0.0589 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0012 | 0.0077 | 0.0511 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0617 | 0.0617 |
Plasmodium falciparum | endonuclease/exonuclease/phosphatase family protein, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0077 | 0.0111 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.371 | 0.371 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0012 | 0.0077 | 0.0004 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0077 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0846 | 0.0901 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2524 | 0.2524 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0077 | 0.0111 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0012 | 0.0077 | 0.0004 |
Brugia malayi | hypothetical protein | 0.0088 | 0.2439 | 0.3505 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.1513 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0607 | 0.4008 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.371 | 0.371 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0028 | 0.0589 | 0.3894 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0012 | 0.0075 | 0.0075 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0446 | 0.2579 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0617 | 0.0887 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0049 | 0.0071 |
Echinococcus multilocularis | deoxyribonuclease 1 2 | 0.0012 | 0.0075 | 0.0075 |
Plasmodium vivax | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | hypothetical protein | 0.0153 | 0.4461 | 0.6411 |
Onchocerca volvulus | 0.0032 | 0.0718 | 0.1516 | |
Plasmodium vivax | endonuclease/exonuclease/phosphatase domain containing protein | 0.0012 | 0.0075 | 0.0494 |
Schistosoma mansoni | eyes absent homolog | 0.0088 | 0.2439 | 0.2439 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0718 | 0.0765 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0037 | 0.0857 | 0.0857 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0058 | 0.1513 | 0.1513 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0037 | 0.0857 | 0.2512 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0846 | 0.5587 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0607 | 0.0607 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0857 | 0.5438 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.371 | 0.5332 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0019 | 0.0311 | 0.0447 |
Loa Loa (eye worm) | cytochrome P450 | 0.0012 | 0.0077 | 0.0082 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0049 | 0.0049 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0049 | 0.0049 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0112 | 0.3189 | 0.3189 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.1189 | 0.1709 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0012 | 0.0077 | 0.0004 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0846 | 0.1119 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0012 | 0.0077 | 0.0004 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Leishmania major | RNA-editing complex protein MP100, putative | 0.0012 | 0.0075 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.008 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0607 | 0.0646 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0009 | 0.0004 | 0.0021 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0028 | 0.0589 | 0.0847 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0846 | 0.1119 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0009 | 0.0004 | 0.0021 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.103 | 0.6643 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.2439 | 0.2598 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0058 | 0.1513 | 0.462 |
Trypanosoma brucei | inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative | 0.0012 | 0.0075 | 0.0494 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0607 | 0.0607 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0846 | 0.514 |
Trypanosoma cruzi | inositol 5-phosphatase 1, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0107 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0607 | 0.3509 |
Leishmania major | endonuclease/exonuclease protein-like protein | 0.0012 | 0.0075 | 0.0476 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0617 | 0.4079 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0795 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0607 | 0.0646 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0049 | 0.0049 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0012 | 0.0077 | 0.0004 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0049 | 0.0071 |
Leishmania major | pantothenate kinase subunit, putative | 0.0012 | 0.0075 | 0.0476 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0012 | 0.0075 | 0.0075 |
Brugia malayi | RNA binding protein | 0.0129 | 0.371 | 0.5332 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0012 | 0.0077 | 0.0511 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0958 | 0.0958 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.2042 | 0.2042 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0857 | 0.0913 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0017 | 0.0254 | 0.0254 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0846 | 1 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0378 | 0.2497 |
Schistosoma mansoni | synaptojanin | 0.0012 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0617 | 0.0658 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.008 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0037 | 0.0857 | 0.0857 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0846 | 0.0901 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0012 | 0.0075 | 0.0494 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0012 | 0.0075 | 0.0494 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0846 | 0.1119 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0037 | 0.0857 | 0.5453 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.1572 | 0.2174 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.0012 | 0.0075 | 0.0075 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0028 | 0.0589 | 0.0847 |
Echinococcus multilocularis | 0.0012 | 0.0077 | 0.0077 | |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0012 | 0.0075 | 0.0494 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | RNA, U transporter 1 | 0.0083 | 0.2288 | 0.3289 |
Schistosoma mansoni | ran | 0.0021 | 0.0378 | 0.0378 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0617 | 0.4079 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0012 | 0.0075 | 0.0494 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0012 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0077 | 0.0082 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0049 | 0.0052 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0058 | 0.1513 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0049 | 0.0049 |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.0717 | 0.103 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.103 | 0.6643 |
Echinococcus granulosus | synaptojanin 1 | 0.0012 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0846 | 0.0901 |
Schistosoma mansoni | hypothetical protein | 0.0312 | 0.9387 | 0.9387 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0049 | 0.0049 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0009 | 0.0004 | 0.0024 |
Echinococcus multilocularis | snurportin 1 | 0.0312 | 0.9387 | 0.9387 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0012 | 0.0077 | 0.0004 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0049 | 0.0071 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0028 | 0.0589 | 0.0589 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.1513 | 0.1513 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0049 | 0.0071 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0037 | 0.0857 | 0.5663 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0846 | 0.5357 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0028 | 0.0589 | 0.3894 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0846 | 0.1119 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0028 | 0.0589 | 0.0589 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0378 | 0.2497 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0049 | 0.0052 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2524 | 0.2524 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0012 | 0.0077 | 0.0004 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0776 | 0.0776 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0846 | 0.5587 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2524 | 0.2524 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0846 | 0.0901 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0058 | 0.1513 | 0.2175 |
Loa Loa (eye worm) | acetyltransferase | 0.0145 | 0.4198 | 0.4472 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0846 | 0.1119 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0049 | 0.0052 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.1572 | 0.1572 |
Trypanosoma cruzi | RNA-editing complex protein MP100, putative | 0.0012 | 0.0075 | 0.0494 |
Onchocerca volvulus | 0.0037 | 0.0846 | 0.1805 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0049 | 0.0049 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0846 | 0.0846 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0028 | 0.0589 | 0.1652 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0049 | 0.0052 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0049 | 0.0049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.371 | 0.371 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0049 | 0.0052 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0446 | 0.1192 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0857 | 0.0913 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0028 | 0.0589 | 0.3409 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0846 | 0.0846 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0857 | 0.1232 |
Plasmodium vivax | exodeoxyribonuclease III, putative | 0.0012 | 0.0075 | 0.0494 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0846 | 0.5379 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.2439 | 0.2598 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.371 | 0.371 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0061 | 0.0065 |
Trypanosoma brucei | Inositol phosphosphingolipids phospholipase C | 0.0012 | 0.0075 | 0.0494 |
Brugia malayi | PHD-finger family protein | 0.0011 | 0.0061 | 0.0088 |
Echinococcus multilocularis | synaptojanin 1 | 0.0012 | 0.0075 | 0.0075 |
Schistosoma mansoni | ran | 0.0021 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.2524 | 0.2689 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0012 | 0.0077 | 0.0004 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0112 | 0.3189 | 0.3189 |
Onchocerca volvulus | 0.0012 | 0.0075 | 0.0058 | |
Onchocerca volvulus | Putative neutral sphingomyelinase | 0.0012 | 0.0075 | 0.0058 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0846 | 0.514 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2524 | 0.2524 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0075 | 0.0432 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0049 | 0.0049 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | = 30 mg kg-1 | Neurotoxicity in ip dosed CF1 albino mouse assessed as dose required to cause toxicity after 4 hrs by rotarod test | ChEMBL. | 20638856 |
Activity (ADMET) | = 30 mg kg-1 | Neurotoxicity in ip dosed CF1 albino mouse assessed as dose required to cause toxicity after 0.5 hrs by rotarod test | ChEMBL. | 20638856 |
Activity (functional) | = 100 mg kg-1 | Anticonvulsant activity in ip dosed CF1 albino mouse assessed as dose required to protect against maximal electroshock-induced seizures after 4 hrs | ChEMBL. | 20638856 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.