Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0646 | 0.8706 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0266 | 0.028 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0009 | 0.0056 | 0.0033 |
Echinococcus granulosus | bloom syndrome protein | 0.0018 | 0.018 | 0.0181 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.0032 | 0.0016 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0.0032 | 0.001 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0266 | 0.0665 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0428 | 0.1106 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0428 | 0.0472 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0169 | 0.0174 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0428 | 0.0472 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0266 | 0.2493 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0007 | 0.0032 | 0.001 |
Echinococcus granulosus | geminin | 0.0155 | 0.2037 | 0.232 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0007 | 0.0032 | 0.001 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.018 | 0.0181 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0019 | 0.0193 | 0.0221 |
Entamoeba histolytica | tartrate dehydrogenase, putative | 0.0078 | 0.0999 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0428 | 0.0472 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0646 | 0.8706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Entamoeba histolytica | recQ family helicase, putative | 0.0018 | 0.018 | 0.1608 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0032 | 0.0016 |
Brugia malayi | conserved hypotetical protein | 0.0009 | 0.0056 | 0.0064 |
Schistosoma mansoni | smad | 0.0009 | 0.0053 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0182 | 0.0209 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.4174 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0169 | 0.0174 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0009 | 0.0056 | 0.0033 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0009 | 0.0056 | 0.0033 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0032 | 0.0036 |
Onchocerca volvulus | 0.0024 | 0.0266 | 0.3861 | |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0018 | 0.018 | 0.0429 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0019 | 0.0193 | 0.017 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase AldC | 0.0007 | 0.0023 | 0.0006 |
Trichomonas vaginalis | glutaminase, putative | 0.0276 | 0.3684 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.038 | 0.0411 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0071 | 0.0055 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0032 | 0.0036 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0009 | 0.0056 | 0.0525 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0266 | 0.0665 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0428 | 0.0491 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0007 | 0.0032 | 0.0088 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0428 | 0.1106 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0009 | 0.0056 | 0.0038 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0009 | 0.0056 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0166 | 0.0164 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0606 | 0.0584 |
Wolbachia endosymbiont of Brugia malayi | isocitrate dehydrogenase | 0.0078 | 0.0999 | 1 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0428 | 0.0491 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.0032 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | Smad1 | 0.0009 | 0.0053 | 0.0061 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.001 | 0.0071 | 0.0048 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0009 | 0.0056 | 0.0064 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0018 | 0.018 | 0.0181 |
Loa Loa (eye worm) | aldehyde dehydrogenase 4 | 0.0007 | 0.0023 | 0.0026 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0032 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0053 | 0.0035 |
Schistosoma mansoni | nuclear hormone receptor | 0.0009 | 0.0056 | 0.0038 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0428 | 0.0466 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0266 | 0.0665 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0009 | 0.0056 | 0.0038 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0053 | 0.0061 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD+) | 0.0078 | 0.0999 | 0.0979 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0023 | 0.0026 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0428 | 0.4147 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.0032 | 0.0016 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0019 | 0.0193 | 0.2694 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0053 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0059 | 0.0068 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0039 | 0.0018 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0428 | 0.0472 |
Brugia malayi | tailless protein | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0428 | 0.0491 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0733 | 0.0818 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0053 | 0.0031 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0018 | 0.018 | 0.0171 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0053 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0182 | 0.0209 |
Entamoeba histolytica | recQ family helicase, putative | 0.0009 | 0.0055 | 0.0324 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.018 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0606 | 0.0671 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0007 | 0.0032 | 0.0088 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD) subunit | 0.0078 | 0.0999 | 0.0979 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0019 | 0.0193 | 0.0196 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0119 | 0.1551 | 0.176 |
Schistosoma mansoni | glutaminase | 0.0276 | 0.3684 | 0.4216 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0071 | 0.0081 |
Brugia malayi | isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0018 | 0.018 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0019 | 0.0193 | 0.017 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0119 | 0.1551 | 0.176 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0007 | 0.0032 | 0.0024 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0666 | 0.0765 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.0032 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.001 | 0.0071 | 0.0081 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0055 | 0.0036 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0119 | 0.1551 | 0.1532 |
Onchocerca volvulus | 0.0007 | 0.0032 | 0.0137 | |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0428 | 0.0472 |
Mycobacterium ulcerans | 3-isopropylmalate dehydrogenase | 0.0078 | 0.0999 | 0.2667 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0646 | 0.8706 | 0.8703 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0009 | 0.0059 | 0.0032 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | Isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0.0032 | 0.001 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0169 | 0.0174 |
Brugia malayi | Succinate semialdehyde dehydrogenase, mitochondrial precursor | 0.0007 | 0.0023 | 0.0026 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0646 | 0.8706 | 1 |
Mycobacterium tuberculosis | Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) | 0.0007 | 0.0023 | 0.0006 |
Leishmania major | isocitrate dehydrogenase, putative | 0.0078 | 0.0999 | 0.1125 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0428 | 0.1106 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0009 | 0.0056 | 0.0038 |
Schistosoma mansoni | Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial | 0.0078 | 0.0999 | 0.1125 |
Echinococcus multilocularis | geminin | 0.0155 | 0.2037 | 0.2019 |
Loa Loa (eye worm) | delta-1-pyrroline-5-carboxylate dehydrogenase | 0.0007 | 0.0023 | 0.0026 |
Brugia malayi | nuclear hormone receptor | 0.0019 | 0.0193 | 0.0221 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.176 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0032 | 0.0016 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0029 | 0.0018 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.0032 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0032 | 0.0036 |
Schistosoma mansoni | thyroid hormone receptor | 0.0019 | 0.0193 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor | 0.0007 | 0.0023 | 0.0026 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0266 | 0.0306 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0019 | 0.0193 | 0.0196 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0166 | 0.0143 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) | 0.0007 | 0.0023 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0032 | 0.0036 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0007 | 0.0032 | 0.0024 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0166 | 0.0164 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0166 | 0.0164 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0064 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0428 | 0.0491 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus multilocularis | bloom syndrome protein | 0.0018 | 0.018 | 0.0157 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0428 | 0.1106 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0032 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0999 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0053 | 0.0035 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0009 | 0.0056 | 0.0038 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | Isocitrate dehydrogenase subunit gamma, mitochondrial precursor | 0.0078 | 0.0999 | 0.1148 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0428 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Brugia malayi | steroid hormone receptor | 0.0019 | 0.0193 | 0.0221 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0032 | 0.0024 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0063 | 0.0072 |
Schistosoma mansoni | hypothetical protein | 0.0155 | 0.2037 | 0.232 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0019 | 0.0193 | 0.0221 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0007 | 0.0032 | 0.0088 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0182 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.176 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0053 | 0.0035 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.018 | 0.0207 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0064 | 0.0042 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0009 | 0.0056 | 0.0033 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0053 | 0.0031 |
Schistosoma mansoni | zinc finger protein | 0.0009 | 0.0056 | 0.0038 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0428 | 0.0466 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0009 | 0.0059 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0019 | 0.0193 | 0.0196 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus granulosus | tumor protein p63 | 0.0362 | 0.485 | 0.556 |
Onchocerca volvulus | 0.0036 | 0.0428 | 0.6421 | |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0053 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0166 | 0.019 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0018 | 0.018 | 0.0429 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0009 | 0.0056 | 0.0525 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0428 | 0.4147 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0053 | 0.0035 |
Mycobacterium tuberculosis | Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 | 0.0007 | 0.0023 | 0.0006 |
Mycobacterium leprae | PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) | 0.0078 | 0.0999 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0428 | 0.0491 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0428 | 0.1106 |
Onchocerca volvulus | 0.0009 | 0.0056 | 0.0525 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0053 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0428 | 0.1106 |
Onchocerca volvulus | 0.0036 | 0.0428 | 0.6421 | |
Brugia malayi | Bloom's syndrome protein homolog | 0.0018 | 0.018 | 0.0207 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0071 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0009 | 0.0059 | 0.0042 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0053 | 0.0035 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0019 | 0.0193 | 0.017 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0009 | 0.0055 | 0.0036 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0019 | 0.0193 | 0.017 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0428 | 0.0466 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0182 | 0.0189 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0009 | 0.0056 | 0.0064 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0646 | 0.8706 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0646 | 0.8706 | 0.8703 |
Loa Loa (eye worm) | DR-78 | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0019 | 0.0193 | 0.0221 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.0829 | 0.0928 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0019 | 0.0193 | 0.0196 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0019 | 0.0193 | 0.2694 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0007 | 0.0032 | 0.001 |
Onchocerca volvulus | 0.0053 | 0.0654 | 1 | |
Schistosoma mansoni | unc-13 (munc13) | 0.0078 | 0.0999 | 0.1125 |
Loa Loa (eye worm) | glutaminase | 0.0276 | 0.3684 | 0.4231 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0266 | 0.0306 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0019 | 0.0193 | 0.0221 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0356 | 0.0409 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.4174 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0007 | 0.0032 | 0.0024 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.0032 | 0.0036 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0182 | 0.0435 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0018 | 0.018 | 0.0181 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase (NAD+) dependent | 0.0007 | 0.0023 | 0.0006 |
Onchocerca volvulus | 0.0007 | 0.0032 | 0.0137 | |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0032 | 0.0036 |
Brugia malayi | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0009 | 0.0056 | 0.0038 |
Schistosoma mansoni | DNA helicase recq1 | 0.0018 | 0.018 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0182 | 0.0209 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0428 | 0.0472 |
Entamoeba histolytica | recQ family DNA helicase | 0.0009 | 0.0059 | 0.0373 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0356 | 0.0409 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0032 | 0.001 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0019 | 0.0193 | 0.0196 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0232 | 0.3089 | 0.3535 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.0078 | 0.0999 | 0.1148 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0266 | 0.0665 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Loa Loa (eye worm) | aldehyde dehydrogenase | 0.0007 | 0.0023 | 0.0026 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0018 | 0.018 | 0.0171 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0018 | 0.018 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Schistosoma mansoni | DNA helicase recq5 | 0.0018 | 0.018 | 0.0181 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0606 | 0.0671 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0018 | 0.018 | 0.0181 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0606 | 0.0671 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0009 | 0.0056 | 0.0038 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0166 | 0.019 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0428 | 0.1106 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0019 | 0.0193 | 0.017 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0071 | 0.0081 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0039 | 0.0016 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0166 | 0.019 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0018 | 0.018 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0266 | 0.0306 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0428 | 0.0472 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0428 | 0.0491 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0428 | 0.0466 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0266 | 0.028 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0019 | 0.0193 | 0.0196 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.038 | 0.0358 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0019 | 0.0193 | 0.0221 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0606 | 0.0671 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0032 | 0.001 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0007 | 0.0032 | 0.0024 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0428 | 0.1106 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.0032 | 0.001 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0007 | 0.0032 | 0.0024 |
Schistosoma mansoni | hypothetical protein | 0.0155 | 0.2037 | 0.232 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0053 | 0.0061 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0064 | 0.0048 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0428 | 0.0472 |
Brugia malayi | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Echinococcus multilocularis | smad | 0.0009 | 0.0053 | 0.0031 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0166 | 0.0164 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0032 | 0.001 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0032 | 0.0024 |
Schistosoma mansoni | nuclear hormone receptor | 0.0009 | 0.0056 | 0.0038 |
Onchocerca volvulus | 0.0007 | 0.0032 | 0.0137 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.4174 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0019 | 0.0193 | 0.2694 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0019 | 0.0193 | 0.0196 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0266 | 0.028 |
Brugia malayi | nuclear hormone receptor | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0666 | 0.0765 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0053 | 0.0654 | 0.0726 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0019 | 0.0193 | 0.0196 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.176 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0009 | 0.0056 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0428 | 0.0491 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0032 | 0.0016 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0009 | 0.0056 | 0.0064 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0009 | 0.0056 | 0.0033 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0018 | 0.018 | 0.0181 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0411 | 0.5521 | 0.6332 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0129 | 0.1687 | 0.1938 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0182 | 0.0174 |
Echinococcus granulosus | neuropeptide s receptor | 0.0411 | 0.5521 | 0.6332 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Mycobacterium ulcerans | glutaminase | 0.0276 | 0.3684 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0266 | 0.0665 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0182 | 0.0174 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0606 | 0.0671 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0007 | 0.0032 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Onchocerca volvulus | 0.0009 | 0.0056 | 0.0525 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0019 | 0.0193 | 0.0196 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0019 | 0.0193 | 0.0221 |
Brugia malayi | nuclear receptor NHR-67 | 0.0009 | 0.0056 | 0.0064 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0019 | 0.0193 | 0.017 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0019 | 0.0193 | 0.0221 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0646 | 0.8706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0182 | 0.0209 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0646 | 0.8706 | 0.8703 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0654 | 0.0751 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0434 | 0.0499 |
Brugia malayi | Aldehyde dehydrogenase protein 4 | 0.0007 | 0.0023 | 0.0026 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0019 | 0.0193 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0266 | 0.2493 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0646 | 0.8706 | 0.8703 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.0032 | 0.0016 |
Treponema pallidum | ATP-dependent DNA helicase | 0.0009 | 0.0059 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0666 | 0.0765 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0428 | 0.0491 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0428 | 0.0491 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0129 | 0.1687 | 0.1938 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0009 | 0.0059 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0169 | 0.0174 |
Trichomonas vaginalis | isocitrate dehydrogenase, putative | 0.0078 | 0.0999 | 0.2667 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0266 | 0.2493 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0266 | 0.0306 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.001 | 0.0071 | 0.0055 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0166 | 0.0164 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0053 | 0.0061 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0032 | 0.0024 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0032 | 0.0016 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | nuclear receptor NHR-88 | 0.0009 | 0.0056 | 0.0064 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0019 | 0.0193 | 0.0221 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0032 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0059 | 0.0068 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0166 | 0.0164 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0059 | 0.0042 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0606 | 0.0696 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0019 | 0.0193 | 0.0196 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0009 | 0.0056 | 0.0038 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0646 | 0.8706 | 1 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0007 | 0.0032 | 0.0024 |
Loa Loa (eye worm) | glutaminase 2 | 0.0276 | 0.3684 | 0.4231 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0606 | 0.0696 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0646 | 0.8706 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0019 | 0.0193 | 0.0196 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0007 | 0.0023 | 0.0006 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | 0.0078 | 0.0999 | 0.1148 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0356 | 0.0383 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0428 | 0.0406 |
Mycobacterium tuberculosis | Probable pyrroline-5-carboxylate dehydrogenase RocA | 0.0007 | 0.0023 | 0.0006 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0646 | 0.8706 | 0.8703 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0428 | 0.0466 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0666 | 0.0765 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0009 | 0.0056 | 0.0038 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0428 | 0.0491 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.038 | 0.0411 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0019 | 0.0193 | 0.0196 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0428 | 0.0472 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0428 | 0.0491 |
Brugia malayi | aldehyde dehydrogenase | 0.0007 | 0.0023 | 0.0026 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0.0032 | 0.001 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0019 | 0.0193 | 0.0196 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0019 | 0.0193 | 0.017 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0428 | 0.0491 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0266 | 0.2493 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0053 | 0.0061 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0166 | 0.019 |
Brugia malayi | glutaminase DH11.1 | 0.0276 | 0.3684 | 0.4231 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0434 | 0.0474 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0428 | 0.1106 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0007 | 0.0032 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | 0.0078 | 0.0999 | 0.1148 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0019 | 0.0193 | 0.017 |
Echinococcus multilocularis | tumor protein p63 | 0.0362 | 0.485 | 0.4838 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus granulosus | isocitrate dehydrogenase NAD subunit | 0.0078 | 0.0999 | 0.1125 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0428 | 0.0472 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0606 | 0.0584 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0428 | 0.0466 |
Onchocerca volvulus | 0.0007 | 0.0032 | 0.0137 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0019 | 0.0193 | 0.0196 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0166 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0221 |
Plasmodium vivax | ATP-dependent DNA helicase Q1, putative | 0.0009 | 0.0055 | 0.0027 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0646 | 0.8706 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.038 | 0.0411 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0019 | 0.0193 | 0.0221 |
Echinococcus granulosus | smad | 0.0009 | 0.0053 | 0.0035 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0266 | 0.0306 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0411 | 0.5521 | 0.551 |
Onchocerca volvulus | 0.0031 | 0.0356 | 0.5277 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0071 | 0.0081 |
Brugia malayi | nuclear receptor RXR | 0.0009 | 0.0056 | 0.0064 |
Schistosoma mansoni | nuclear receptor | 0.0009 | 0.0056 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0019 | 0.0193 | 0.0221 |
Onchocerca volvulus | 0.0019 | 0.0193 | 0.2694 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0032 | 0.0036 |
Schistosoma mansoni | thyroid hormone receptor | 0.0019 | 0.0193 | 0.0196 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Loa Loa (eye worm) | isocitrate dehydrogenase gamma subunit | 0.0078 | 0.0999 | 0.1148 |
Onchocerca volvulus | 0.0036 | 0.0428 | 0.6421 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0032 | 0.0036 |
Brugia malayi | ecdysteroid receptor | 0.0019 | 0.0193 | 0.0221 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0119 | 0.1551 | 0.1765 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0166 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.018 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0266 | 0.0306 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0411 | 0.5521 | 0.551 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0182 | 0.0209 |
Loa Loa (eye worm) | RecQ helicase | 0.0018 | 0.018 | 0.0207 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0019 | 0.0193 | 0.0196 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0019 | 0.0193 | 0.017 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0266 | 0.0665 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0053 | 0.0061 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0039 | 0.0016 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0007 | 0.0032 | 0.001 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0029 | 0.0018 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0019 | 0.0193 | 0.0196 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0053 | 0.0035 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0428 | 0.1106 |
Brugia malayi | ecdysone receptor | 0.0009 | 0.0056 | 0.0064 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0018 | 0.018 | 0.0157 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0428 | 0.0466 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0039 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0032 | 0.0036 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0019 | 0.0193 | 0.0221 |
Mycobacterium tuberculosis | Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde | 0.0007 | 0.0023 | 0.0006 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.0032 | 0.0036 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0007 | 0.0032 | 0.0009 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0266 | 0.0665 |
Echinococcus granulosus | FTZ F1 alpha | 0.0019 | 0.0193 | 0.0196 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0029 | 0.0018 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0009 | 0.0056 | 0.0064 |
Echinococcus granulosus | isocitrate dehydrogenase NAD | 0.0078 | 0.0999 | 0.1125 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.001 | 0.0071 | 0.0055 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0018 | 0.018 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0018 | 0.018 | 0.0181 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0053 | 0.0035 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0166 | 0.0143 |
Mycobacterium tuberculosis | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) | 0.0078 | 0.0999 | 0.113 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0646 | 0.8706 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0019 | 0.0193 | 0.0196 |
Mycobacterium tuberculosis | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 | 0.0007 | 0.0023 | 0.0006 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.0032 | 0.001 |
Brugia malayi | nuclear receptor NHR-88 | 0.0019 | 0.0193 | 0.0221 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0266 | 0.0286 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0266 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0434 | 0.0499 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0428 | 0.0457 |
Schistosoma mansoni | nuclear receptor | 0.0009 | 0.0056 | 0.0038 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0266 | 0.2493 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0019 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0056 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0023 | 0.0026 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0266 | 0.0665 |
Schistosoma mansoni | isocitrate dehydrogenase | 0.0078 | 0.0999 | 0.1125 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.0032 | 0.0016 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.0078 | 0.0999 | 0.1148 |
Brugia malayi | MH2 domain containing protein | 0.0129 | 0.1687 | 0.1938 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.018 | 0.0207 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0428 | 0.0466 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.0193 | 0.0196 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0039 | 0.0018 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 20.3 ug ml-1 | Antiproliferative activity against human LoVo cells | ChEMBL. | 20022253 |
IC50 (functional) | > 100 ug ml-1 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release | ChEMBL. | 20022253 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.