Detailed information for compound 1103549

Basic information

Technical information
  • TDR Targets ID: 1103549
  • Name: [9-(1,3-benzodioxol-5-yl)-7-(hydroxymethyl)be nzo[g][1,3]benzodioxol-8-yl]methanol
  • MW: 352.337 | Formula: C20H16O6
  • H donors: 2 H acceptors: 2 LogP: 2.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCc1cc2ccc3c(c2c(c1CO)c1ccc2c(c1)OCO2)OCO3
  • InChi: 1S/C20H16O6/c21-7-13-5-11-2-4-16-20(26-10-24-16)19(11)18(14(13)8-22)12-1-3-15-17(6-12)25-9-23-15/h1-6,21-22H,7-10H2
  • InChiKey: ABUPIJWHLLSVCH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [9-(1,3-benzodioxol-5-yl)-7-(hydroxymethyl)-8-benzo[g][1,3]benzodioxolyl]methanol
  • [9-(1,3-benzodioxol-5-yl)-7-methylol-benzo[g][1,3]benzodioxol-8-yl]methanol
  • ZHU-IX-124-2
  • 2,3--Dihydroxymethyl-5,6-methylenedioxy-4-(3',4'-methylenedioxyphenyl)napthalene
  • AIDS-122253
  • AIDS122253

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus beta LACTamase domain containing family member 0.0338 0.1498 0.1505
Echinococcus granulosus phosphoglycerate mutase 0.0036 0.0089 0.0081
Toxoplasma gondii heat shock protein HSP90 0.0032 0.007 0.0367
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0262 0.0265
Echinococcus granulosus zinc finger protein 0.0022 0.0022 0.0013
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0036 0.0089 0.034
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.004 0.0031
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0097 0.0098
Leishmania major hypothetical protein, unknown function 0.0036 0.0089 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0304 0.5042
Plasmodium vivax heat shock protein 86, putative 0.0032 0.007 0.0367
Brugia malayi latrophilin 2 splice variant baaae 0.0145 0.0596 0.2838
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.004 0.0028
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.0338 0.1498 0.6336
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.022 0.021
Schistosoma mansoni hypothetical protein 0.1555 0.7183 0.7255
Onchocerca volvulus 0.0338 0.1498 0.1436
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0338 0.1498 0.2559
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0036 0.0089 0.0328
Echinococcus granulosus histone lysine methyltransferase setb 0.0085 0.0316 0.031
Leishmania major hypothetical protein, conserved 0.0036 0.0089 0.009
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Brugia malayi MH1 domain containing protein 0.0025 0.004 0.0118
Leishmania major DNA polymerase kappa, putative 0.0023 0.0028 0.0028
Schistosoma mansoni Smad4 0.0025 0.004 0.004
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0039 0.0116
Echinococcus multilocularis Endonuclease G 0.0025 0.0036 0.0028
Mycobacterium tuberculosis Conserved protein 0.0036 0.0089 0.0074
Toxoplasma gondii phosphoglycerate mutase family protein 0.0036 0.0089 0.0497
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.013 0.0132
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0029 0.0073
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.007 0.007
Echinococcus granulosus phosphoglycerate mutase 0.0036 0.0089 0.0081
Trypanosoma brucei hypothetical protein, conserved 0.0338 0.1498 0.1513
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0233 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0064 0.022 0.0222
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.0829 0.3977
Schistosoma mansoni hypothetical protein 0.0089 0.0337 0.0341
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0212 0.0909 0.4365
Loa Loa (eye worm) endoplasmin 0.0032 0.007 0.0058
Brugia malayi Calcitonin receptor-like protein seb-1 0.0212 0.0909 0.4365
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0041 0.0114 0.0115
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0036 0.0089 0.0328
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0829 0.0837
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0035 0.0083 0.0075
Loa Loa (eye worm) hypothetical protein 0.0082 0.0304 0.0295
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0079 0.0288 0.0279
Brugia malayi Smad1 0.0025 0.004 0.0118
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0038 0.0038
Treponema pallidum phosphoglyceromutase 0.0036 0.0089 1
Leishmania major phosphoglycerate mutase protein, putative 0.0036 0.0089 0.009
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0304 0.0307
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0143 0.059 0.0596
Brugia malayi UBASH3A protein homolog 0.0036 0.0089 0.036
Toxoplasma gondii phosphoglycerate mutase family protein 0.0036 0.0089 0.0497
Trypanosoma brucei endonuclease G, putative 0.0025 0.0036 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0233 0.0223
Brugia malayi heat shock protein 90 0.0032 0.007 0.0266
Mycobacterium ulcerans beta-lactamase 0.0338 0.1498 0.2559
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0092 0.0084
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.0829 0.0826
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0036 0.0089 0.0081
Echinococcus granulosus phosphoglycerate mutase 0.0036 0.0089 0.0081
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0025 0.0036 0.0037
Loa Loa (eye worm) phosphoglycerate mutase 0.0036 0.0089 0.0078
Echinococcus granulosus GPCR family 2 0.0067 0.0233 0.0226
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0304 0.5042
Brugia malayi TAR-binding protein 0.0064 0.022 0.0999
Loa Loa (eye worm) hypothetical protein 0.0338 0.1498 0.1503
Echinococcus granulosus ectonucleotide 0.0035 0.0083 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.1498 0.1513
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.004 0.0031
Toxoplasma gondii LsmAD domain-containing protein 0.0082 0.0304 0.1944
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0262 0.0256
Echinococcus multilocularis heat shock protein 0.0032 0.007 0.0061
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0036 0.0089 0.0081
Schistosoma mansoni phosphoglycerate mutase 0.0036 0.0089 0.009
Brugia malayi hypothetical protein 0.0073 0.0262 0.1206
Brugia malayi Importin beta-1 subunit 0.0029 0.0055 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2137 0.99 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0238 0.0241
Echinococcus granulosus 6 phosphofructo 2 kinase:fructose 2 0.2137 0.99 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0143 0.059 0.0585
Mycobacterium ulcerans lipase LipD 0.0338 0.1498 0.2559
Loa Loa (eye worm) hypothetical protein 0.0043 0.012 0.0109
Trichomonas vaginalis penicillin-binding protein, putative 0.0338 0.1498 0.6336
Mycobacterium tuberculosis Probable lipase LipE 0.0338 0.1498 0.1485
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0036 0.0089 0.0328
Loa Loa (eye worm) transcription factor SMAD2 0.0374 0.1667 0.1674
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0104 0.0096
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.007 0.0094
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0036 0.0089 0.0328
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0829 0.0829
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0028 0.0028
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.007 0.007
Leishmania major hypothetical protein, conserved 0.0338 0.1498 0.1513
Echinococcus multilocularis ectonucleotide 0.0035 0.0083 0.0075
Plasmodium falciparum heat shock protein 90 0.0032 0.007 0.0997
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Echinococcus multilocularis zinc finger protein 0.0022 0.0022 0.0013
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0085 0.0469
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0231 0.0224
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0028 0.0013
Loa Loa (eye worm) hypothetical protein 0.0036 0.0089 0.0078
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.2101 0.9732 0.983
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0143 0.059 0.0992
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0238 0.0228
Onchocerca volvulus 0.0089 0.0337 0.0253
Entamoeba histolytica hypothetical protein 0.0073 0.0262 0.0426
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0238 0.0232
Trypanosoma brucei glycerolphosphate mutase, putative 0.0036 0.0089 0.009
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0079 0.008
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Brugia malayi Thrombospondin type 1 domain containing protein 0.0089 0.0337 0.1573
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0079 0.008
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0089 0.0337 0.0329
Toxoplasma gondii phosphoglycerate mutase 0.0036 0.0089 0.0497
Echinococcus multilocularis dna polymerase kappa 0.0045 0.013 0.0123
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.2137 0.99 1
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0036 0.0089 0.0074
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0025 0.0036 0.0037
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1705 0.7883 0.796
Echinococcus granulosus endoplasmin 0.0025 0.0039 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0015 0.0014
Echinococcus granulosus snurportin 1 0.0307 0.1352 0.1358
Mycobacterium tuberculosis Conserved protein 0.0036 0.0089 0.0074
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0304 0.0307
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Mycobacterium tuberculosis Conserved protein 0.0338 0.1498 0.1485
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0041 0.0114 0.0115
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0036 0.0089 0.009
Echinococcus multilocularis phosphoglycerate mutase 0.0036 0.0089 0.0081
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0233 0.1065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.013 0.0132
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0233 0.1065
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0238 0.0241
Echinococcus granulosus tar DNA binding protein 0.0064 0.022 0.0213
Echinococcus multilocularis beta LACTamase domain containing family member 0.0338 0.1498 0.1505
Loa Loa (eye worm) hypothetical protein 0.0041 0.0114 0.0102
Echinococcus multilocularis phosphoglycerate mutase 0.0036 0.0089 0.0081
Schistosoma mansoni heat shock protein 0.0032 0.007 0.007
Schistosoma mansoni rotamase 0.0036 0.0089 0.009
Schistosoma mansoni zinc finger protein 0.0022 0.0022 0.0022
Giardia lamblia Hypothetical protein 0.1261 0.581 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0028 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.013 0.0132
Schistosoma mansoni hypothetical protein 0.1555 0.7183 0.7255
Mycobacterium ulcerans hydrolase MutT1 0.0036 0.0089 0.0127
Plasmodium vivax ataxin-2 like protein, putative 0.0082 0.0304 0.1944
Trichomonas vaginalis rotamase, putative 0.0035 0.0085 0.0311
Plasmodium vivax phosphoglucomutase-2, putative 0.0036 0.0089 0.0497
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Leishmania major hypothetical protein, conserved 0.0036 0.0089 0.009
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0143 0.059 0.0596
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0036 0.0089 0.009
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Schistosoma mansoni endoplasmin 0.0032 0.007 0.007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0829 0.0829
Echinococcus multilocularis heat shock protein 90 0.0032 0.007 0.0061
Treponema pallidum heat shock protein 90 0.0025 0.0039 0.3261
Brugia malayi polk-prov protein 0.0034 0.0079 0.0313
Echinococcus granulosus proteasome prosome macropain 0.0143 0.059 0.0588
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0231 0.0224
Echinococcus multilocularis GPCR, family 2 0.0067 0.0233 0.0226
Entamoeba histolytica hypothetical protein 0.0073 0.0262 0.0426
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0143 0.059 0.0992
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.007 0.0094
Plasmodium falciparum proteasome subunit beta type-5 0.0143 0.059 1
Echinococcus multilocularis proteasome (prosome, macropain) 0.0143 0.059 0.0588
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.013 0.0199
Plasmodium vivax SET domain protein, putative 0.0066 0.0228 0.1432
Mycobacterium ulcerans hypothetical protein 0.0036 0.0089 0.0127
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.013 0.0132
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0085 0.012
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0036 0.0089 0.0127
Schistosoma mansoni hypothetical protein 0.0036 0.0089 0.009
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.007 0.007
Leishmania major importin beta-1 subunit, putative 0.0023 0.0029 0.003
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Echinococcus multilocularis endoplasmin 0.0025 0.0039 0.0031
Mycobacterium ulcerans hypothetical protein 0.0036 0.0089 0.0127
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.007 0.0367
Trichomonas vaginalis rotamase, putative 0.0036 0.0089 0.0327
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0036 0.0089 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0107 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0029 0.003
Trichomonas vaginalis heat shock protein, putative 0.0032 0.007 0.0246
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0238 0.0241
Loa Loa (eye worm) hypothetical protein 0.0041 0.0114 0.0102
Mycobacterium ulcerans phosphoglycerate mutase 0.0036 0.0089 0.0127
Mycobacterium ulcerans esterase/lipase LipP 0.0338 0.1498 0.2559
Trichomonas vaginalis esterase, putative 0.0338 0.1498 0.6336
Trichomonas vaginalis set domain proteins, putative 0.0522 0.2357 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.004 0.0031
Loa Loa (eye worm) hypothetical protein 0.2137 0.99 1
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0212 0.0909 0.0906
Echinococcus multilocularis snurportin 1 0.0307 0.1352 0.1358
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0338 0.1498 0.1485
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0036 0.0089 0.0081
Leishmania major glycerolphosphate mutase, putative 0.0036 0.0089 0.009
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0143 0.059 0.0596
Entamoeba histolytica hypothetical protein 0.0073 0.0262 0.0426
Loa Loa (eye worm) hypothetical protein 0.0212 0.0909 0.0906
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.0036 0.0089 0.0127
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0143 0.059 0.0576
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0005 0.0005
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0104 0.0096
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.007 0.007
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0338 0.1498 0.1485
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0015 0.0006
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0338 0.1498 0.7247
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0036 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0338 0.1498 0.1503
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0036 0.0089 0.034
Mycobacterium leprae Probable lipase LipE 0.0338 0.1498 1
Loa Loa (eye worm) hypothetical protein 0.0338 0.1498 0.1503
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.004 0.004
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0041 0.0114 0.0115
Brugia malayi RNA, U transporter 1 0.0082 0.0302 0.14
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0036 0.0089 0.5
Schistosoma mansoni smad1 5 8 and 0.0025 0.004 0.004
Schistosoma mansoni tar DNA-binding protein 0.0064 0.022 0.0222
Echinococcus multilocularis heat shock protein 90 0.0025 0.0039 0.0031
Echinococcus multilocularis phosphoglycerate mutase 0.0036 0.0089 0.0081
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0092 0.0084
Toxoplasma gondii phosphoglycerate mutase family protein 0.0036 0.0089 0.0497
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0912 0.4179 0.4221
Plasmodium vivax endoplasmin, putative 0.0032 0.007 0.0367
Trypanosoma brucei endonuclease G, putative 0.0025 0.0036 0.0037
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Plasmodium vivax proteasome subunit beta type-5, putative 0.0143 0.059 0.3878
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0015 0.0015
Schistosoma mansoni smad1 5 8 and 0.0025 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0079 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0089 0.0327
Brugia malayi Bromodomain containing protein 0.0043 0.0119 0.0509
Onchocerca volvulus 0.0066 0.0228 0.0141
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0829 0.0829
Schistosoma mansoni hypothetical protein 0.0023 0.0028 0.0028
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0036 0.0089 0.009
Onchocerca volvulus 0.0041 0.0114 0.0025
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.0912 0.4179 0.4221
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0142 0.0131
Schistosoma mansoni tar DNA-binding protein 0.0064 0.022 0.0222
Loa Loa (eye worm) hypothetical protein 0.0041 0.0114 0.0102
Loa Loa (eye worm) beta-lactamase 0.0338 0.1498 0.1503
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0067 0.0233 0.0235
Brugia malayi phosphoglycerate mutase family protein 0.0036 0.0089 0.036
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0085 0.0086
Schistosoma mansoni hypothetical protein 0.0073 0.0262 0.0265
Leishmania major phosphoglycerate mutase family member 5, putative 0.0036 0.0089 0.009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0066 0.0228 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0039 0.0041
Brugia malayi Pre-SET motif family protein 0.0066 0.0228 0.1038
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0036 0.0089 0.009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0338 0.1498 0.1503
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0143 0.059 0.3777
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0262 0.0256
Schistosoma mansoni hypothetical protein 0.0036 0.0089 0.009
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0912 0.4179 0.4221
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0036 0.0089 0.0074
Leishmania major hypothetical protein, conserved 0.0036 0.0089 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0085 0.0316 0.0319
Brugia malayi Proteasome A-type and B-type family protein 0.0143 0.059 0.281
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0036 0.0089 0.009
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0238 0.0241
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0085 0.0316 0.031
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0036 0.0089 0.009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0233 0.0226
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0038 0.0029
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0089 0.034
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0085 0.0086
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0045 0.013 0.0504
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0005 0.0005
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0039 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0085 0.0316 0.0319
Brugia malayi MH2 domain containing protein 0.0025 0.004 0.0118
Echinococcus multilocularis expressed protein 0.0036 0.0089 0.0081
Mycobacterium ulcerans phosphoglyceromutase 0.0036 0.0089 0.0127
Brugia malayi beta-lactamase family protein 0.0338 0.1498 0.7247
Loa Loa (eye worm) heat shock protein 90 0.0032 0.007 0.0058
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0036 0.0089 0.0127
Brugia malayi beta-lactamase family protein 0.0338 0.1498 0.7247
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Loa Loa (eye worm) hypothetical protein 0.0338 0.1498 0.1503
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0338 0.1498 0.1485
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0107 0.0099
Brugia malayi MH2 domain containing protein 0.0374 0.1667 0.8073
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.0036 0.0089 0.0127
Echinococcus granulosus geminin 0.1555 0.7183 0.7252
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0036 0.0089 0.009
Trypanosoma brucei phosphoglycerate mutase, putative 0.0036 0.0089 0.009
Brugia malayi hypothetical protein 0.0082 0.0304 0.1409
Schistosoma mansoni hypothetical protein 0.0036 0.0089 0.009
Schistosoma mansoni endoplasmin 0.0032 0.007 0.007
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0829 0.0829
Schistosoma mansoni tar DNA-binding protein 0.0064 0.022 0.0222
Brugia malayi RNA binding protein 0.0064 0.022 0.0999
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.007 0.0094
Mycobacterium ulcerans hypothetical protein 0.0338 0.1498 0.2559
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0015 0.0015
Brugia malayi Pre-SET motif family protein 0.0459 0.2062 1
Mycobacterium tuberculosis Probable esterase LipL 0.0338 0.1498 0.1485
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0238 0.0232
Brugia malayi endonuclease G, mitochondrial precursor 0.0025 0.0036 0.0104
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0338 0.1498 0.1513
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0089 0.034
Echinococcus granulosus heat shock protein 90 0.0025 0.0039 0.0031
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0039 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0374 0.1667 0.1674
Plasmodium falciparum phosphoglucomutase-2 0.0036 0.0089 0.1331
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0055 0.0265
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0015 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Leishmania major endonuclease G, putative 0.0025 0.0036 0.0037
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0233 0.0223
Loa Loa (eye worm) hypothetical protein 0.0036 0.0089 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.013 0.0132
Echinococcus granulosus heat shock protein 0.0032 0.007 0.0061
Loa Loa (eye worm) hypothetical protein 0.0338 0.1498 0.1503
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.0228 0.023
Schistosoma mansoni hypothetical protein 0.0067 0.0233 0.0235
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Schistosoma mansoni tar DNA-binding protein 0.0064 0.022 0.0222
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0066 0.0228 0.1432
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0039 0.004
Loa Loa (eye worm) hypothetical protein 0.0145 0.0596 0.059
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.007 0.007
Plasmodium vivax importin-beta 2, putative 0.0029 0.0055 0.0265
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0015 0.0003
Mycobacterium tuberculosis Conserved protein 0.0338 0.1498 0.1485
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0055 0.0046
Echinococcus granulosus phosphoglycerate mutase 0.0036 0.0089 0.0081
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0036 0.0089 0.034
Echinococcus multilocularis phosphoglycerate mutase 0.0036 0.0089 0.0081
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0089 0.0077
Giardia lamblia DINP protein human, muc B family 0.0023 0.0028 0.0022
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0036 0.0089 0.0074
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0055 0.0055
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2137 0.99 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0228 0.023
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Schistosoma mansoni heat shock protein 0.0032 0.007 0.007
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0036 0.0089 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Mycobacterium leprae conserved hypothetical protein 0.0338 0.1498 1
Onchocerca volvulus 0.0041 0.0114 0.0025
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0009 0.0009
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0036 0.0089 0.009
Schistosoma mansoni bromodomain containing protein 0.007 0.0249 0.0252
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0024
Echinococcus granulosus heat shock protein 90 0.0032 0.007 0.0061
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0036 0.0089 0.009
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0009 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0015 0.0006
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0036 0.0089 0.0127
Leishmania major proteasome beta 5 subunit, putative 0.0143 0.059 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0089 0.0328
Mycobacterium leprae Possible phosphoglycerate mutase 0.0036 0.0089 0.034
Schistosoma mansoni smad1 5 8 and 0.0025 0.004 0.004
Brugia malayi Bromodomain containing protein 0.0083 0.031 0.1441
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0036 0.0089 0.0074
Giardia lamblia Grp94/Hsp90 0.0025 0.0039 0.0041
Echinococcus multilocularis Smad4 0.0025 0.004 0.0031
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0233 0.0226
Mycobacterium ulcerans hypothetical protein 0.1261 0.581 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0089 0.0078
Mycobacterium tuberculosis Probable lipase LipD 0.0338 0.1498 0.1485
Onchocerca volvulus 0.0338 0.1498 0.1436
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0035 0.0083 0.0075
Mycobacterium ulcerans proteasome PrcB 0.0143 0.059 0.0992
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0005 0.0005
Brugia malayi beta-lactamase 0.0338 0.1498 0.7247
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2101 0.9732 0.983
Mycobacterium tuberculosis Conserved protein 0.0338 0.1498 0.1485
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0089 0.0359
Echinococcus granulosus Smad4 0.0025 0.004 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.1498 0.1513
Schistosoma mansoni hypothetical protein 0.0067 0.0233 0.0235
Brugia malayi PHD-finger family protein 0.0028 0.005 0.0169
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0041 0.0114 0.048
Mycobacterium ulcerans acid phosphatase 0.0036 0.0089 0.0127
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.013 0.0132
Loa Loa (eye worm) Smad1 0.0025 0.004 0.0028
Echinococcus multilocularis phosphoglycerate mutase 0.0036 0.0089 0.0081
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0041 0.0114 0.0115
Schistosoma mansoni phosphoglycerate mutase 0.0036 0.0089 0.009
Brugia malayi hypothetical protein 0.0053 0.0168 0.0745
Echinococcus multilocularis smad 0.0025 0.004 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0338 0.1498 0.6336
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0036 0.0089 0.0328
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0304 0.0307
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Schistosoma mansoni hypothetical protein 0.0036 0.0089 0.009
Schistosoma mansoni hypothetical protein 0.0037 0.0092 0.0093
Trypanosoma cruzi endonuclease G, putative 0.0025 0.0036 0.0037
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.013 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0338 0.1498 0.6336
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.004 0.0031
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0025 0.0036 0.0037
Plasmodium falciparum importin beta, putative 0.0029 0.0055 0.0737
Echinococcus granulosus dna polymerase kappa 0.0045 0.013 0.0123
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0132 0.0121
Echinococcus multilocularis geminin 0.1555 0.7183 0.7252
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0912 0.4179 0.4221
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0036 0.0089 0.009
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1261 0.581 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0338 0.1498 0.6336
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0216 0.0209
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0015 0.0056
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2101 0.9732 0.983
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0085 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.013 0.0132
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0036 0.0089 0.009
Schistosoma mansoni importin beta-1 0.0029 0.0055 0.0055
Plasmodium falciparum phosphoglycerate mutase, putative 0.0036 0.0089 0.1331
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0829 0.0837
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.0039 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0073
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0143 0.059 0.2466
Leishmania major phosphoglycerate mutase, putative 0.0036 0.0089 0.009
Trypanosoma brucei heat shock protein, putative 0.0032 0.007 0.007
Echinococcus multilocularis phosphoglycerate mutase 0.0036 0.0089 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0829 0.0837
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0039 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0089 0.0328
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0055 0.0055
Mycobacterium leprae probable isochorismate synthase EntC 0.0036 0.0089 0.034
Brugia malayi MH1 domain containing protein 0.0025 0.004 0.0118
Schistosoma mansoni hypothetical protein 0.0036 0.0089 0.009
Schistosoma mansoni endonuclease related 0.0025 0.0036 0.0037
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0028 0.0016
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0089 0.034
Echinococcus granulosus importin subunit beta 1 0.0029 0.0055 0.0046
Loa Loa (eye worm) hypothetical protein 0.0338 0.1498 0.1503
Loa Loa (eye worm) hypothetical protein 0.0029 0.0055 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0089 0.0074
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0009 0.0009
Schistosoma mansoni 6-phosphofructokinase 0.2137 0.99 1
Trypanosoma brucei endonuclease G, putative 0.0025 0.0036 0.0037
Entamoeba histolytica hypothetical protein 0.0073 0.0262 0.0426
Mycobacterium ulcerans lipoprotein LpqD 0.0036 0.0089 0.0127
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0459 0.2062 0.2073
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.1352 0.1355
Giardia lamblia Hypothetical protein 0.1261 0.581 1
Loa Loa (eye worm) hypothetical protein 0.2101 0.9732 0.983
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0036 0.0089 0.034
Schistosoma mansoni hypothetical protein 0.0036 0.0089 0.009
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0085 0.0086
Onchocerca volvulus 0.0338 0.1498 0.1436
Brugia malayi MH2 domain containing protein 0.0025 0.004 0.0118
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0036 0.0089 0.0497
Echinococcus granulosus Endonuclease G 0.0025 0.0036 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0233 0.0226
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0036 0.0089 0.0074
Schistosoma mansoni ap endonuclease 0.002 0.0015 0.0015
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0039 0.0041
Loa Loa (eye worm) TAR-binding protein 0.0064 0.022 0.021
Loa Loa (eye worm) hypothetical protein 0.0085 0.0316 0.0307
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2101 0.9732 0.983
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0238 0.0241
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0143 0.059 0.0596
Onchocerca volvulus 0.2137 0.99 1
Brugia malayi Endoplasmin precursor 0.0032 0.007 0.0266
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0039 0.004
Trypanosoma brucei unspecified product 0.0038 0.0097 0.0098
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0015 0.0014
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0036 0.0089 0.009
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0073
Brugia malayi phosphoglycerate mutase family protein 0.0036 0.0089 0.036
Leishmania major hypothetical protein, conserved 0.0082 0.0304 0.0307
Leishmania major heat shock protein 83-1 0.0032 0.007 0.007
Loa Loa (eye worm) RNA binding protein 0.0064 0.022 0.021
Schistosoma mansoni ap endonuclease 0.002 0.0015 0.0015
Toxoplasma gondii proteasome subunit beta type, putative 0.0143 0.059 0.3878
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0238 0.0385
Trichomonas vaginalis DNA polymerase eta, putative 0.0045 0.013 0.0504
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.007 0.007
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2137 0.99 1
Echinococcus multilocularis tar DNA binding protein 0.0064 0.022 0.0213
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0036 0.0089 0.0081
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.022 0.0999
Onchocerca volvulus 0.0522 0.2357 0.2312
Plasmodium vivax hypothetical protein, conserved 0.0338 0.1498 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0089 0.0078
Schistosoma mansoni hypothetical protein 0.0307 0.1352 0.1366
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.004 0.0028
Echinococcus granulosus expressed protein 0.0036 0.0089 0.0081
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0041 0.0114 0.0106
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0039 0.0024
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0025 0.0036 0.0143
Toxoplasma gondii phosphoglycerate mutase family protein 0.0036 0.0089 0.0497
Toxoplasma gondii ABC1 family protein 0.0338 0.1498 1
Plasmodium vivax phosphoglycerate mutase, putative 0.0036 0.0089 0.0497
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0338 0.1498 0.1513
Trypanosoma cruzi endonuclease G, putative 0.0025 0.0036 0.0037
Mycobacterium ulcerans phosphoglycerate mutase 0.0036 0.0089 0.0127
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0036 0.0089 0.009
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0238 0.1089
Mycobacterium tuberculosis Probable hydrolase 0.0338 0.1498 0.1485
Loa Loa (eye worm) hypothetical protein 0.1225 0.5642 0.5693
Echinococcus granulosus smad 0.0025 0.004 0.0031
Echinococcus granulosus phosphoglycerate mutase 0.0036 0.0089 0.0081
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0038 0.0029
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2137 0.99 1
Schistosoma mansoni smad 0.0025 0.004 0.004
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1261 0.581 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0083 0.0072
Schistosoma mansoni hypothetical protein 0.0145 0.0596 0.0602
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0039 0.004
Schistosoma mansoni hypothetical protein 0.0067 0.0233 0.0235

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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