Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0324 | 0.0324 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.8833 | 1 |
Schistosoma mansoni | lamin | 0.0029 | 0.36 | 0.385 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.8833 | 0.8833 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.5522 | 0.5522 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.36 | 0.385 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.8833 | 0.8833 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.36 | 0.36 |
Onchocerca volvulus | 0.0029 | 0.36 | 0.5 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.8833 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.8833 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.8833 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.8833 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.8833 | 1 |
Echinococcus multilocularis | musashi | 0.0029 | 0.36 | 0.385 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.8833 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.3458 | 0.3458 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.5522 | 0.6108 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.36 | 0.36 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0324 | 0.0324 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.36 | 0.385 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.36 | 0.385 |
Schistosoma mansoni | lamin | 0.0029 | 0.36 | 0.385 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0324 | 0.0324 |
Onchocerca volvulus | 0.0029 | 0.36 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.5522 | 0.5522 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.36 | 0.36 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.36 | 0.36 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0324 | 0.0324 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.36 | 0.385 |
Echinococcus multilocularis | lamin | 0.0029 | 0.36 | 0.385 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.36 | 0.36 |
Echinococcus granulosus | lamin | 0.0029 | 0.36 | 0.385 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.