Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.9424 | 1 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.0211 | 1 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0108 | 0.4217 | 0.4217 |
Brugia malayi | RNA binding protein | 0.0201 | 0.9424 | 0.9424 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0111 | 0.4424 | 0.4424 |
Loa Loa (eye worm) | RNA binding protein | 0.0201 | 0.9424 | 0.9424 |
Loa Loa (eye worm) | TAR-binding protein | 0.0201 | 0.9424 | 0.9424 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0111 | 0.4424 | 0.4424 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0108 | 0.4217 | 0.4217 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.2313 | 0.2313 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.0211 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.4217 | 0.4217 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0104 | 0.0104 |
Brugia malayi | TAR-binding protein | 0.0201 | 0.9424 | 0.9424 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.0211 | 1 | 0.5 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.2313 | 0.2313 |
Echinococcus granulosus | tar DNA binding protein | 0.0201 | 0.9424 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0108 | 0.4217 | 0.4217 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0201 | 0.9424 | 0.9424 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.0211 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.9424 | 1 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.0211 | 1 | 0.5 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.0211 | 1 | 0.5 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.0211 | 1 | 0.5 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.2313 | 0.237 |
Echinococcus multilocularis | tar DNA binding protein | 0.0201 | 0.9424 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0211 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0104 | 0.0104 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0211 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.9424 | 1 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0201 | 0.9424 | 0.9424 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0211 | 1 | 0.5 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.9424 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.9424 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.