TDR Targets

Basic information

Technical information

TDR Targets ID: 111047
Name: 1-[[5-[2-(3,4-dichlorophenyl)acetyl]-6,7-dihy dro-4H-furo[3,2-c]pyridin-4-yl]methyl]pyrroli din-3-one
MW: 407.29 | Formula: C20H20Cl2N2O3
H donors: 0 H acceptors: 2 LogP: 2.83 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=C1CCN(C1)CC1N(CCc2c1cco2)C(=O)Cc1ccc(c(c1)Cl)Cl
InChi: 1S/C20H20Cl2N2O3/c21-16-2-1-13(9-17(16)22)10-20(26)24-7-4-19-15(5-8-27-19)18(24)12-23-6-3-14(25)11-23/h1-2,5,8-9,18H,3-4,6-7,10-12H2
InChiKey: AJKUPPVEURAWOP-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

1-[[5-[2-(3,4-dichlorophenyl)-1-oxoethyl]-6,7-dihydro-4H-furo[3,2-c]pyridin-4-yl]methyl]-3-pyrrolidinone
1-[[5-[2-(3,4-dichlorophenyl)ethanoyl]-6,7-dihydro-4H-furo[3,2-c]pyridin-4-yl]methyl]pyrrolidin-3-one
1-[[5-[2-(3,4-dichlorophenyl)acetyl]-6,7-dihydro-4H-furo[3,2-c]pyridin-4-yl]methyl]-3-pyrrolidone

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	opioid receptor, kappa 1	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0022	0.0017
Schistosoma mansoni	coup transcription factor	0.001	0.0022	0.0017
Mycobacterium tuberculosis	Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.001	0.0022	0.0017
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0023	0.0094	0.1798
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0099	0.0501	1
Brugia malayi	photoreceptor-specific nuclear receptor	0.001	0.0022	0.0037
Onchocerca volvulus		0.0023	0.0094	0.1798
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0094	0.0089
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0022	0.0037
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0022	0.0037
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0023	0.0094	0.1798
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0062	0.0057
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.001	0.0022	0.0338
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.0099	0.0501	1
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.0099	0.0501	1
Brugia malayi	Peptidase family M1 containing protein	0.0099	0.0501	0.1084
Mycobacterium tuberculosis	Peptide synthetase MbtF (peptide synthase)	0.0007	0.0005	0.0546
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0094	0.1798
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.001	0.0022	0.0017
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0799	0.4285	0.4282
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.001	0.0022	0.0017
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.001	0.0022	0.0037
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0094	0.0089
Brugia malayi	hypothetical protein	0.0099	0.0501	0.1084
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.001	0.0022	0.0037
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.0099	0.0501	1
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0022	0.0037
Mycobacterium tuberculosis	Probable peptide synthetase Nrp (peptide synthase)	0.0007	0.0005	0.0546
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0022	0.0017
Schistosoma mansoni	RAR-like nuclear receptor	0.001	0.0022	0.0017
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0094	0.1798
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.001	0.0022	0.0037
Brugia malayi	TATA binding protein associated factor	0.0099	0.0501	0.1084
Schistosoma mansoni	cytosol alanyl aminopeptidase (M01 family)	0.0099	0.0501	0.0496
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Loa Loa (eye worm)	aminopeptidase N	0.0099	0.0501	0.0496
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0017	0.0062	0.1154
Echinococcus granulosus	ecdysone induced protein 78C	0.001	0.0022	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0062	0.0057
Brugia malayi	Nuclear hormone receptor-like 1	0.001	0.0022	0.0037
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.1858	1	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.001	0.0022	0.0017
Onchocerca volvulus		0.001	0.0022	0.0338
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.001	0.0022	0.0017
Onchocerca volvulus		0.0099	0.0501	1
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.1858	1	1
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0062	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0099	0.0501	0.0496
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0094	0.0195
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0099	0.0501	1
Brugia malayi	Peptidase family M1 containing protein	0.0099	0.0501	0.1084
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.001	0.0022	0.0017
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0023	0.0094	0.1798
Trypanosoma cruzi	metallo-peptidase, Clan MA(E) Family M1	0.0099	0.0501	1
Schistosoma mansoni	steroid hormone receptor ad4bp	0.001	0.0022	0.0017
Onchocerca volvulus	Bile acid receptor homolog	0.001	0.0022	0.0338
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0022	0.0017
Trypanosoma cruzi	aminopeptidase, putative	0.0099	0.0501	1
Brugia malayi	nuclear receptor NHR-88	0.001	0.0022	0.0037
Echinococcus granulosus	aminopeptidase N	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Onchocerca volvulus		0.0099	0.0501	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.001	0.0022	0.0017
Mycobacterium tuberculosis	Peptide synthetase MbtE (peptide synthase)	0.0007	0.0005	0.0546
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.001	0.0022	0.0017
Trypanosoma cruzi	aminopeptidase, putative	0.0099	0.0501	1
Mycobacterium ulcerans	aminopeptidase N PepN	0.0099	0.0501	1
Brugia malayi	nuclear hormone receptor	0.001	0.0022	0.0037
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0099	0.0501	1
Leishmania major	4-coumarate:coa ligase-like protein	0.0023	0.0094	0.1798
Plasmodium vivax	acyl-CoA synthetase, putative	0.0017	0.0062	0.1154
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.1858	1	1
Brugia malayi	Peptidase family M1 containing protein	0.0099	0.0501	0.1084
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0023	0.0094	1
Loa Loa (eye worm)	steroid hormone receptor	0.001	0.0022	0.0017
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.001	0.0022	0.0017
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0017	0.0062	0.5
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0062	0.0057
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.001	0.0022	0.0017
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.001	0.0022	0.0017
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0023	0.0094	0.1798
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0023	0.0094	0.1798
Brugia malayi	hypothetical protein	0.0854	0.458	1
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.001	0.0022	0.0017
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.001	0.0022	0.0017
Toxoplasma gondii	aminopeptidase N protein	0.0099	0.0501	1
Mycobacterium tuberculosis	Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase)	0.0007	0.0005	0.0546
Mycobacterium tuberculosis	P-hydroxybenzoyl-AMP ligase FadD22	0.0007	0.0005	0.0546
Mycobacterium tuberculosis	Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	0.0007	0.0005	0.0546
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0094	0.0195
Loa Loa (eye worm)	peptidase family M1 containing protein	0.0099	0.0501	0.0496
Onchocerca volvulus	Protein ultraspiracle homolog	0.001	0.0022	0.0338
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.001	0.0022	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0099	0.0501	0.0496
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0023	0.0094	1
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.001	0.0022	0.0017
Toxoplasma gondii	aminopeptidase n, putative	0.0099	0.0501	1
Schistosoma mansoni	Tata binding protein associated factor (M01 family)	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0017	0.0057	0.6071
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.001	0.0022	0.0017
Onchocerca volvulus		0.0099	0.0501	1
Trypanosoma cruzi	Aminopeptidase M1, putative	0.0099	0.0501	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.001	0.0022	0.0017
Trypanosoma brucei	aminopeptidase, putative	0.0099	0.0501	1
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.0099	0.0501	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.001	0.0022	0.0017
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0023	0.0094	1
Brugia malayi	ecdysteroid receptor	0.001	0.0022	0.0037
Trypanosoma brucei	Aminopeptidase M1, putative	0.0099	0.0501	1
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0023	0.0094	0.1798
Plasmodium falciparum	M1-family alanyl aminopeptidase, putative	0.0099	0.0501	1
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.001	0.0022	0.0037
Leishmania major	4-coumarate:coa ligase-like protein	0.0023	0.0094	0.1798
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.0099	0.0501	1
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.001	0.0022	0.0017
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0022	0.0037
Plasmodium falciparum	acyl-CoA synthetase	0.0017	0.0062	0.1154
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0094	0.0195
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.0007	0.0005	0.0546
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0017	0.0057	0.6071
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.0099	0.0501	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0017	0.0057	0.6071
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Schistosoma mansoni	retinoic acid receptor RXR	0.001	0.0022	0.0017
Echinococcus granulosus	FTZ F1 alpha	0.001	0.0022	0.0017
Trypanosoma brucei	Aminopeptidase M1, putative	0.0099	0.0501	1
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0022	0.0037
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.001	0.0022	0.0037
Brugia malayi	hypothetical protein	0.0099	0.0501	0.1084
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.0099	0.0501	1
Brugia malayi	Steroid receptor seven-up type 2	0.001	0.0022	0.0037
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0094	0.1798
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0022	0.0017
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.0099	0.0501	1
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.001	0.0022	0.0037
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0022	0.0017
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0023	0.0094	1
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.001	0.0022	0.0017
Echinococcus multilocularis	thyroid hormone receptor alpha	0.001	0.0022	0.0017
Leishmania major	puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.0099	0.0501	1
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.001	0.0022	0.0037
Schistosoma mansoni	nuclear hormone receptor	0.001	0.0022	0.0017
Echinococcus multilocularis	Peptidase M1, membrane alanine aminopeptidase, N terminal	0.0099	0.0501	0.0496
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0017	0.0057	0.6071
Loa Loa (eye worm)	TATA binding protein associated factor	0.0099	0.0501	0.0496
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0062	0.0057
Entamoeba histolytica	acyl-coA synthetase, putative	0.0023	0.0094	0.1798
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.001	0.0022	0.0017
Plasmodium falciparum	M1-family alanyl aminopeptidase	0.0099	0.0501	1
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0022	0.0037
Leishmania major	4-coumarate:coa ligase-like protein	0.0023	0.0094	0.1798
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0022	0.0017
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Loa Loa (eye worm)	hypothetical protein	0.001	0.0022	0.0017
Schistosoma mansoni	aminopeptidase A (M01 family)	0.0099	0.0501	0.0496
Mycobacterium ulcerans	aminopeptidase N PepN	0.0099	0.0501	1
Brugia malayi	steroid hormone receptor	0.001	0.0022	0.0037
Entamoeba histolytica	aminopeptidase, putative	0.0099	0.0501	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.001	0.0022	0.0017
Mycobacterium ulcerans	hypothetical protein	0.0023	0.0094	0.1798
Echinococcus multilocularis	ecdysone induced protein 78C	0.001	0.0022	0.0017
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0099	0.0501	1
Echinococcus multilocularis	aminopeptidase N	0.0099	0.0501	0.0496
Echinococcus multilocularis	FTZ F1 alpha	0.001	0.0022	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0094	0.0089
Toxoplasma gondii	aminopeptidase N, putative	0.0099	0.0501	1
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0099	0.0501	0.0496
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0017	0.0062	0.6617
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0099	0.0501	1

Activities

Activity type	Activity value	Assay description	Source	Reference
ED50 (functional)	= 0.019 mg kg-1	Antinociceptive activity was measured using the mouse acetylcholine-induced abdominal constriction test following subcutaneous administration of the compound	ChEMBL.	8035420
ED50 (functional)	= 0.019 mg kg-1	Antinociceptive activity was measured using the mouse acetylcholine-induced abdominal constriction test following subcutaneous administration of the compound	ChEMBL.	8035420
IC50 (functional)	= 6 nM	In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assay	ChEMBL.	8035420
IC50 (functional)	= 6 nM	In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assay	ChEMBL.	8035420

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL70226
PubChem: 14933785

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 111047