Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | DNA helicase recq5 | 0.0012 | 0.0194 | 0.0428 |
Loa Loa (eye worm) | RNA binding protein | 0.0139 | 0.454 | 0.9807 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1395 | 0.2763 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.03 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1456 | 0.2904 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0323 | 0.0291 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0028 | 0.0757 | 0.0461 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0323 | 0.0296 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0019 | 0.0447 | 0.5 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0015 | 0.0311 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0139 | 0.454 | 0.9807 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0323 | 0.0296 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0323 | 0.0296 |
Schistosoma mansoni | DNA helicase recq1 | 0.0012 | 0.0194 | 0.0428 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1395 | 0.2763 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0028 | 0.0757 | 0.1296 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1395 | 0.3073 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0323 | 0.0296 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1456 | 0.2849 |
Brugia malayi | RNA binding protein | 0.0139 | 0.454 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0022 | 0.0555 | 0.1223 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1395 | 0.2763 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1395 | 0.2763 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0323 | 0.0296 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.0439 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0028 | 0.0757 | 0.0461 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Entamoeba histolytica | recQ family helicase, putative | 0.0015 | 0.0311 | 0.0311 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0147 | 0.4782 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0012 | 0.0194 | 0.4422 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0147 | 0.4782 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.03 | 1 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0139 | 0.454 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0932 | 0.1697 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0932 | 0.2052 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0323 | 0.0296 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1395 | 0.3073 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0323 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1456 | 0.2849 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0025 | 0.0641 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0139 | 0.454 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.1395 | 0.271 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0323 | 0.0296 |
Echinococcus granulosus | bloom syndrome protein | 0.0028 | 0.0757 | 0.1296 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0323 | 0.0296 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0015 | 0.0311 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0139 | 0.454 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.4625 | 1 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0015 | 0.0311 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1395 | 0.3073 |
Brugia malayi | TAR-binding protein | 0.0139 | 0.454 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0012 | 0.0194 | 0.4422 |
Echinococcus multilocularis | bloom syndrome protein | 0.0028 | 0.0757 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0932 | 0.1665 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1456 | 0.2904 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0147 | 0.4782 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.1395 | 0.2763 |
Loa Loa (eye worm) | RecQ helicase | 0.0028 | 0.0757 | 0.1271 |
Loa Loa (eye worm) | TAR-binding protein | 0.0139 | 0.454 | 0.9807 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.