Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0159 | 0.5454 | 0.8213 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0164 | 0.5622 | 0.8467 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.006 | 0.181 | 0.181 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0042 | 0.1152 | 0.1152 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0013 | 0.0083 | 0.009 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.006 | 0.181 | 0.4497 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.006 | 0.181 | 1 |
Loa Loa (eye worm) | phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Loa Loa (eye worm) | glutaminase | 0.0283 | 1 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0164 | 0.5622 | 0.5622 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0107 | 0.3526 | 0.3526 |
Echinococcus multilocularis | dna polymerase kappa | 0.0042 | 0.1152 | 0.1735 |
Schistosoma mansoni | glutaminase | 0.0283 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0083 | 0.0083 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0164 | 0.5622 | 0.5622 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0014 | 0.01 | 0.0134 |
Plasmodium vivax | NLI interacting factor-like phosphatase, putative | 0.0014 | 0.01 | 0.0298 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0013 | 0.0083 | 0.0083 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0879 | 0.0879 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Schistosoma mansoni | ap endonuclease | 0.006 | 0.181 | 0.181 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0014 | 0.01 | 0.01 |
Schistosoma mansoni | ap endonuclease | 0.006 | 0.181 | 0.181 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.006 | 0.181 | 0.4497 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Brugia malayi | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0107 | 0.3526 | 0.5309 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Echinococcus granulosus | CCR4 NOT transcription complex subunit 6 | 0.0012 | 0.0048 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0048 | 0.0048 |
Toxoplasma gondii | Dullard family phosphatase domain-containing protein | 0.0014 | 0.01 | 0.0554 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.007 | 0.2175 | 0.5427 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.006 | 0.181 | 0.1741 |
Echinococcus multilocularis | CCR4 NOT transcription complex subunit 6 | 0.0012 | 0.0048 | 0.0072 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.1581 | 0.3912 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0971 | 0.1462 |
Echinococcus multilocularis | synaptojanin 1 | 0.0012 | 0.0048 | 0.0072 |
Loa Loa (eye worm) | RecQ helicase | 0.0026 | 0.0566 | 0.0566 |
Loa Loa (eye worm) | acetyltransferase | 0.0164 | 0.5622 | 0.5622 |
Trichomonas vaginalis | ap endonuclease, putative | 0.006 | 0.181 | 0.1771 |
Echinococcus multilocularis | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0012 | 0.0048 | 0.0072 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0048 | 0.1373 | 0.7517 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 0.3966 | 0.3937 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Trypanosoma brucei | unspecified product | 0.0029 | 0.0671 | 0.159 |
Brugia malayi | polk-prov protein | 0.0013 | 0.0083 | 0.0083 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.006 | 0.181 | 0.4497 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.01 | 0.01 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0021 | 0.0363 | 0.0363 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.664 | 0.664 |
Echinococcus granulosus | geminin | 0.0192 | 0.664 | 1 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0048 | 0.0048 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 0.3966 | 0.3937 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0042 | 0.1152 | 0.2817 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3916 |
Toxoplasma gondii | exonuclease III APE | 0.006 | 0.181 | 1 |
Plasmodium vivax | NLI interacting factor-like phosphatase, putative | 0.0014 | 0.01 | 0.0298 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0971 | 0.0971 |
Plasmodium falciparum | exodeoxyribonuclease III, putative | 0.0012 | 0.0048 | 0.0265 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0044 | 0.1225 | 0.3475 |
Brugia malayi | Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 | 0.0014 | 0.01 | 0.01 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.006 | 0.181 | 0.4497 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0013 | 0.0083 | 0.009 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0119 | 0.3966 | 0.5973 |
Schistosoma mansoni | synaptojanin | 0.0012 | 0.0048 | 0.0048 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0013 | 0.0083 | 0.0459 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.006 | 0.181 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0000000001812 | 0.000000001001 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0032 | 0.0781 | 0.4316 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.006 | 0.181 | 0.181 |
Schistosoma mansoni | cript-related | 0.0012 | 0.0048 | 0.0048 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.1544 | 0.1504 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0048 | 0.1373 | 0.7583 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0012 | 0.0048 | 0.0072 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.006 | 0.181 | 0.4497 |
Echinococcus multilocularis | dna polymerase eta | 0.007 | 0.2175 | 0.3275 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1152 | 0.2817 |
Echinococcus granulosus | Carboxy terminal domain RNA polymerase II | 0.0014 | 0.01 | 0.0151 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0107 | 0.3526 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0026 | 0.0566 | 0.0521 |
Trichomonas vaginalis | glutaminase, putative | 0.0283 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0671 | 0.159 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0032 | 0.0781 | 0.4316 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0023 | 0.0449 | 0.248 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0119 | 0.3966 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0048 | 0.0048 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0042 | 0.1152 | 0.2817 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0042 | 0.1152 | 0.1078 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0119 | 0.3966 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0042 | 0.1152 | 0.1109 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0971 | 0.2355 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.0012 | 0.0048 | 0.0072 |
Giardia lamblia | DNA damage repair protein | 0.0013 | 0.0083 | 0.0236 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0042 | 0.1152 | 0.2817 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0032 | 0.0781 | 0.4161 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0044 | 0.1225 | 0.3004 |
Echinococcus granulosus | synaptojanin 1 | 0.0012 | 0.0048 | 0.0072 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0013 | 0.0083 | 0.0459 |
Echinococcus multilocularis | 0.0014 | 0.01 | 0.0151 | |
Echinococcus granulosus | traf and tnf receptor associated protein | 0.0012 | 0.0048 | 0.0072 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0107 | 0.3526 | 0.3526 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.006 | 0.181 | 0.2726 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.0246 | 0.136 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0971 | 0.2355 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0119 | 0.3966 | 1 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0012 | 0.0048 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0048 | 0.0048 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0014 | 0.01 | 0.0053 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0012 | 0.0048 | 0.0048 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0107 | 0.3526 | 0.5309 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0.0781 | 0.5 |
Echinococcus multilocularis | geminin | 0.0192 | 0.664 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0042 | 0.1152 | 0.3267 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0971 | 0.0971 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0054 | 0.1581 | 0.8732 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0054 | 0.1581 | 0.8732 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Schistosoma mansoni | synaptojanin | 0.0012 | 0.0048 | 0.0048 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0048 | 0.1373 | 0.1331 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.1544 | 0.1504 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Brugia malayi | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0048 | 0.0048 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0032 | 0.0781 | 0.1871 |
Giardia lamblia | Inositol 5-phosphatase 4 | 0.0012 | 0.0048 | 0.0136 |
Brugia malayi | phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0048 | 0.0048 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.006 | 0.181 | 0.4497 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0042 | 0.1152 | 0.1152 |
Echinococcus granulosus | dna polymerase kappa | 0.0042 | 0.1152 | 0.1735 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0013 | 0.0083 | 0.009 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0041 | 0.1106 | 0.6109 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0013 | 0.0083 | 0.009 |
Schistosoma mansoni | DNA polymerase eta | 0.007 | 0.2175 | 0.2175 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0119 | 0.3966 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0971 | 0.1462 |
Giardia lamblia | hypothetical protein | 0.0012 | 0.0048 | 0.0136 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0107 | 0.3526 | 0.8875 |
Plasmodium falciparum | endonuclease/exonuclease/phosphatase family protein, putative | 0.0012 | 0.0048 | 0.0265 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0119 | 0.3966 | 0.5973 |
Echinococcus granulosus | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0012 | 0.0048 | 0.0072 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0083 | 0.009 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0971 | 0.2355 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0054 | 0.1581 | 0.8698 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.1106 | 0.27 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0042 | 0.1152 | 0.2817 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.049 | 0.0737 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0013 | 0.0083 | 0.009 |
Echinococcus multilocularis | deoxyribonuclease 1 2 | 0.0012 | 0.0048 | 0.0072 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0671 | 0.159 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.006 | 0.181 | 0.4497 |
Trypanosoma brucei | polo-like protein kinase | 0.0107 | 0.3526 | 0.8875 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 0.3966 | 0.3937 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.006 | 0.181 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0671 | 0.159 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0032 | 0.0781 | 0.4316 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0971 | 0.0971 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0013 | 0.0083 | 0.009 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0032 | 0.0781 | 0.4316 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0032 | 0.0781 | 0.1871 |
Echinococcus granulosus | dna polymerase eta | 0.007 | 0.2175 | 0.3275 |
Echinococcus granulosus | CTD small phosphatase protein like | 0.0014 | 0.01 | 0.0151 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0048 | 0.0048 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0013 | 0.0083 | 0.009 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.006 | 0.181 | 0.2726 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0014 | 0.01 | 0.0053 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0044 | 0.1225 | 0.6768 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0042 | 0.1152 | 0.1078 |
Schistosoma mansoni | carbon catabolite repressor protein | 0.0012 | 0.0048 | 0.0048 |
Echinococcus multilocularis | traf and tnf receptor associated protein | 0.0012 | 0.0048 | 0.0072 |
Schistosoma mansoni | kinase | 0.0054 | 0.1596 | 0.1596 |
Leishmania major | DNA polymerase kappa, putative | 0.0013 | 0.0083 | 0.009 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.664 | 0.664 |
Loa Loa (eye worm) | glutaminase 2 | 0.0283 | 1 | 1 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0014 | 0.01 | 0.0053 |
Brugia malayi | CCR4 | 0.0012 | 0.0048 | 0.0048 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0014 | 0.01 | 0.01 |
Trichomonas vaginalis | dullard protein, putative | 0.0014 | 0.01 | 0.0053 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0.0781 | 0.5 |
Trichomonas vaginalis | dullard protein, putative | 0.0014 | 0.01 | 0.0053 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0026 | 0.0566 | 0.0566 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2175 | 0.2175 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0971 | 0.2355 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0012 | 0.0048 | 0.0265 |
Schistosoma mansoni | ocrl type II inositol 5-phosphatase | 0.0012 | 0.0048 | 0.0048 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0119 | 0.3966 | 1 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0117 | 0.0176 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Schistosoma mansoni | nocturnin | 0.0012 | 0.0048 | 0.0048 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1152 | 0.2817 |
Echinococcus granulosus | neutral sphingomyelinase | 0.0012 | 0.0048 | 0.0072 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1152 | 0.2817 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0119 | 0.3966 | 0.5 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Loa Loa (eye worm) | CCR4-NOT transcription complex subunit 6 family protein | 0.0012 | 0.0048 | 0.0048 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0014 | 0.01 | 0.0053 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.3526 | 0.3494 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0048 | 0.1373 | 0.2067 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0048 | 0.0048 |
Leishmania major | hypothetical protein, conserved | 0.0014 | 0.01 | 0.0134 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0026 | 0.0566 | 0.0521 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0048 | 0.1373 | 0.1331 |
Leishmania major | DNA polymerase eta, putative | 0.007 | 0.2175 | 0.5427 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0054 | 0.1581 | 0.3912 |
Trypanosoma brucei | unspecified product | 0.0029 | 0.0671 | 0.159 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0083 | 0.009 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0013 | 0.0083 | 0.009 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0119 | 0.3966 | 1 |
Trichomonas vaginalis | dullard protein, putative | 0.0014 | 0.01 | 0.0053 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0107 | 0.3526 | 0.8875 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0012 | 0.0048 | 0.0072 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0032 | 0.0781 | 0.2216 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 0.3966 | 0.3937 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1152 | 0.2817 |
Echinococcus multilocularis | Carboxy terminal domain RNA polymerase II | 0.0014 | 0.01 | 0.0151 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0117 | 0.0176 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0119 | 0.3966 | 1 |
Brugia malayi | hypothetical protein | 0.0054 | 0.1581 | 0.1581 |
Leishmania major | DNA damage repair protein, putative | 0.0013 | 0.0083 | 0.009 |
Giardia lamblia | Kinase, PLK | 0.0107 | 0.3526 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.3526 | 0.8875 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.007 | 0.2175 | 0.5427 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1581 | 0.1581 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0018 | 0.0254 | 0.1169 |
Leishmania major | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0042 | 0.1152 | 0.1152 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0265 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0014 | 0.0117 | 0.0069 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0013 | 0.0083 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.4454 | 0.4454 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.049 | 0.049 |
Plasmodium falciparum | NLI interacting factor-like phosphatase, putative | 0.0014 | 0.01 | 0.0554 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0042 | 0.1152 | 0.1735 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.1581 | 0.3912 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0119 | 0.3966 | 1 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.3526 | 0.3526 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0012 | 0.0048 | 0.0048 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.1581 | 0.3912 |
Plasmodium falciparum | DNase I-like protein, putative | 0.0012 | 0.0048 | 0.0265 |
Trypanosoma brucei | Mitochondrial import inner membrane translocase subunit TIM50 | 0.0014 | 0.01 | 0.0134 |
Echinococcus multilocularis | bloom syndrome protein | 0.0026 | 0.0566 | 0.0852 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0032 | 0.0781 | 0.4161 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0117 | 0.0176 |
Echinococcus granulosus | bloom syndrome protein | 0.0026 | 0.0566 | 0.0852 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0012 | 0.0048 | 0.0048 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Entamoeba histolytica | recQ family helicase, putative | 0.0014 | 0.0117 | 0.0176 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0042 | 0.1152 | 0.1109 |
Entamoeba histolytica | NLI interacting factor-like phosphatase domain-containing protein | 0.0014 | 0.01 | 0.0134 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0048 | 0.1373 | 0.7583 |
Giardia lamblia | Nuclear LIM interactor-interacting factor 1 | 0.0014 | 0.01 | 0.0285 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0054 | 0.1581 | 0.8732 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1152 | 0.2817 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0013 | 0.0083 | 0.0459 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0032 | 0.0781 | 0.4316 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0781 | 0.0737 |
Trichomonas vaginalis | ap endonuclease, putative | 0.006 | 0.181 | 0.1771 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.007 | 0.2175 | 0.2175 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.1106 | 0.27 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0119 | 0.3966 | 0.3966 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.3526 | 0.8875 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0013 | 0.0083 | 0.02 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0042 | 0.1152 | 0.1735 |
Mycobacterium ulcerans | glutaminase | 0.0283 | 1 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.049 | 0.0737 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.006 | 0.181 | 0.5134 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0042 | 0.1152 | 0.1152 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 25 uM | Inhibition of CRM1-mediated hemagglutininin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by indirect fluorescent antibody technique | ChEMBL. | 20493693 |
Inhibition (binding) | = 2.6 % | Inhibition of CRM1-mediated hemagglutininin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization at 25 uM after 12 hrs by indirect fluorescent antibody technique | ChEMBL. | 20493693 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.