Detailed information for compound 1111486

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 313.825 | Formula: C18H20ClN3
  • H donors: 1 H acceptors: 1 LogP: 3.92 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC([C@@H](c1nc2c(n1Cc1ccc(cc1)Cl)cccc2)N)C
  • InChi: 1S/C18H20ClN3/c1-12(2)17(20)18-21-15-5-3-4-6-16(15)22(18)11-13-7-9-14(19)10-8-13/h3-10,12,17H,11,20H2,1-2H3/t17-/m0/s1
  • InChiKey: GDDZKLGDACVNDP-KRWDZBQOSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0008 0.004 0.0053
Leishmania major DNA damage repair protein, putative 0.0071 0.1198 0.1936
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0648 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0081 0.0093
Leishmania major DNA polymerase eta, putative 0.0339 0.6189 1
Trichomonas vaginalis dullard protein, putative 0.0027 0.0391 0.0391
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0648 0.0739
Schistosoma mansoni hypothetical protein 0.0027 0.0385 0.0505
Trichomonas vaginalis DNA polymerase eta, putative 0.0228 0.4117 0.4117
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0334 0.0481
Brugia malayi beta-lactamase family protein 0.0079 0.1356 0.1546
Echinococcus granulosus FTZ F1 alpha 0.0414 0.758 0.995
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0648 0.0991
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0643 0.3454
Brugia malayi Pre-SET motif family protein 0.0069 0.1169 0.1333
Plasmodium falciparum flap endonuclease 1 0.0027 0.039 0.2095
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Trichomonas vaginalis Phospholipase C precursor, putative 0.0008 0.0039 0.0039
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.004 0.0046
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0008 0.0039 0.0062
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.1356 0.178
Loa Loa (eye worm) hypothetical protein 0.0008 0.004 0.0046
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.1356 0.178
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.1083 0.1422
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0648 0.3481
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0478 0.8774 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0017 0.0197 0.0224
Onchocerca volvulus 0.0017 0.0197 0.0159
Loa Loa (eye worm) hypothetical protein 0.0017 0.0197 0.0224
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0066 0.0087
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0027 0.0391 0.0632
Echinococcus multilocularis snurportin 1 0.0351 0.6414 0.8419
Brugia malayi Importin beta-1 subunit 0.0033 0.0496 0.0565
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0008 0.0039 0.0051
Echinococcus multilocularis L aminoadipate semialdehyde 0.0095 0.1657 0.2175
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.038 0.0556
Echinococcus multilocularis geminin 0.0178 0.3193 0.4191
Schistosoma mansoni hypothetical protein 0.0416 0.7618 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.039 0.039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.1169 0.1535
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0081 0.0107
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.1356 0.1425
Brugia malayi hypothetical protein 0.0008 0.004 0.0046
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0008 0.004 0.0053
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0648 1
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0081 0.0107
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0095 0.1657 0.2175
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0081 0.0093
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0094
Echinococcus granulosus CTD small phosphatase protein like 0.0027 0.0391 0.0514
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0027 0.0383 0.0372
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.1356 0.1425
Brugia malayi hypothetical protein 0.0017 0.0197 0.0224
Loa Loa (eye worm) hypothetical protein 0.0079 0.1356 0.1546
Echinococcus multilocularis neutral sphingomyelinase 0.0008 0.0039 0.0051
Loa Loa (eye worm) G protein alpha subunit 3 0.0008 0.004 0.0046
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.1029 0.3147
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0602 0.0791
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0039 0.0062
Echinococcus multilocularis traf and tnf receptor associated protein 0.0008 0.0039 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0008 0.004 0.0053
Brugia malayi SEA domain containing protein 0.0016 0.0175 0.0199
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.1169 0.1535
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0334 0.0381
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.004 0.0053
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0008 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Brugia malayi ImpB/MucB/SamB family protein 0.0339 0.6189 0.7054
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0027 0.0391 0.0514
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0039 0.0044
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0039 0.0039
Brugia malayi Flap endonuclease-1 0.0027 0.039 0.0445
Plasmodium vivax SET domain protein, putative 0.0069 0.1169 0.6282
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.1198 0.1936
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0008 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0016 0.0175 0.0199
Echinococcus multilocularis dna polymerase eta 0.0339 0.6189 0.8124
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.1862 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0602 0.0687
Brugia malayi hypothetical protein 0.0069 0.1161 0.1323
Echinococcus multilocularis flap endonuclease 1 0.0027 0.039 0.0512
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0066 0.0087
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0391 0.0391
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0008 0.0039 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0081 0.0107
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0648 0.0648
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.1169 0.1535
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0008 0.004 0.0046
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0602 0.0917
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.1169 0.1535
Echinococcus granulosus dna polymerase eta 0.0339 0.6189 0.8124
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Trypanosoma brucei DNA polymerase IV, putative 0.0228 0.4117 0.6653
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0008 0.004 0.0046
Schistosoma mansoni nocturnin 0.0008 0.0039 0.0051
Onchocerca volvulus 0.0079 0.1356 0.1323
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Loa Loa (eye worm) hypothetical protein 0.0033 0.0496 0.0565
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.3511 0.461
Loa Loa (eye worm) hypothetical protein 0.0027 0.0391 0.0446
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.004 0.0046
Plasmodium vivax importin-beta 2, putative 0.0033 0.0496 0.2664
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0081 0.0107
Entamoeba histolytica hypothetical protein 0.0027 0.038 0.0924
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0383 0.0619
Loa Loa (eye worm) hypothetical protein 0.0008 0.004 0.0046
Leishmania major DNA polymerase kappa, putative 0.0071 0.1198 0.1936
Loa Loa (eye worm) hypothetical protein 0.0069 0.1169 0.1333
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0602 0.0791
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.1862 1
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0008 0.004 0.0053
Onchocerca volvulus 0.0011 0.0081 0.0043
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Leishmania major hypothetical protein, conserved 0.0008 0.0039 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0081 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0081 0.0093
Brugia malayi Protein kinase domain containing protein 0.0017 0.0197 0.0224
Leishmania major hypothetical protein, conserved 0.0027 0.0391 0.0632
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0069 0.1169 0.1535
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0081 0.0093
Schistosoma mansoni neutral sphingomyelinase 0.0008 0.0039 0.0051
Trichomonas vaginalis helicase, putative 0.0007 0.0007 0.0007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0648 0.1494
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Brugia malayi nuclear hormone receptor 0.0011 0.0081 0.0093
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0008 0.0039 0.0051
Echinococcus multilocularis dnaJ subfamily B 0.0416 0.7618 1
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0027 0.0391 0.2102
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0648 0.0851
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0602 0.0791
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0771 0.1012
Onchocerca volvulus 0.0008 0.004 0.0002
Onchocerca volvulus 0.0079 0.1356 0.1323
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0039 0.0207
Trypanosoma brucei DNA polymerase kappa, putative 0.0157 0.2804 0.453
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0648 0.071
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Trypanosoma brucei unspecified product 0.0157 0.2804 0.453
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0039 0.0207
Schistosoma mansoni hypothetical protein 0.0017 0.0197 0.0258
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0027 0.0391 0.0514
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Onchocerca volvulus 0.0095 0.1657 0.1625
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.1198 0.1936
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.1356 0.1425
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0081 0.0107
Mycobacterium ulcerans hypothetical protein 0.0079 0.1356 0.2606
Echinococcus granulosus dnaJ subfamily B 0.0416 0.7618 1
Trichomonas vaginalis dullard protein, putative 0.0027 0.0391 0.0391
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.1356 0.2606
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0008 0.004 0.004
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0496 0.0801
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0039 0.0062
Entamoeba histolytica Flap nuclease, putative 0.0027 0.039 0.0947
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0027 0.0391 0.1197
Loa Loa (eye worm) hypothetical protein 0.0016 0.0175 0.0199
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0008 0.0039 0.0062
Leishmania major hypothetical protein, conserved 0.0079 0.1356 0.2191
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0643 0.1482
Plasmodium vivax DNA repair protein REV1, putative 0.0071 0.1198 0.6436
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0008 0.0039 0.0039
Onchocerca volvulus 0.0017 0.0197 0.0159
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0081 0.0107
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0027 0.0391 0.0446
Leishmania major hypothetical protein, conserved 0.0008 0.0039 0.0062
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0334 0.0481
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0008 0.004 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.3511 0.461
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0008 0.0039 0.0039
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0008 0.0039 0.0044
Trichomonas vaginalis set domain proteins, putative 0.0544 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.1356 0.1356
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0066 0.0087
Echinococcus granulosus cpg binding protein 0.0031 0.0458 0.0602
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.1169 0.3577
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0081 0.0107
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0228 0.4117 0.5405
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.039 0.0572
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.1169 0.1535
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.1198 0.1936
Leishmania major endonuclease/exonuclease protein-like protein 0.0008 0.0039 0.0062
Giardia lamblia DNA damage repair protein 0.0071 0.1198 0.2843
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0008 0.004 0.0053
Schistosoma mansoni GTP-binding protein alpha subunit 0.0008 0.004 0.0053
Brugia malayi Pre-SET motif family protein 0.0478 0.8774 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0427 0.0487
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0081 0.0093
Brugia malayi RNA, U transporter 1 0.0094 0.1624 0.1851
Onchocerca volvulus 0.0016 0.0175 0.0137
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0081 0.0093
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0008 0.004 0.0053
Schistosoma mansoni synaptojanin 0.0008 0.0039 0.0051
Schistosoma mansoni hypothetical protein 0.0008 0.0039 0.0051
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0099 0.013
Brugia malayi ImpB/MucB/SamB family protein 0.0228 0.4117 0.4693
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0039 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Onchocerca volvulus 0.0008 0.004 0.0002
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0008 0.004 0.004
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0602 0.0791
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0008 0.004 0.0046
Brugia malayi CXXC zinc finger family protein 0.0029 0.0427 0.0487
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0081 0.0107
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.038 0.038
Leishmania major GTP-binding protein, putative 0.0024 0.0334 0.054
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.1356 0.1546
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0334 0.1023
Trypanosoma cruzi DNA damage repair protein, putative 0.0071 0.1198 0.1885
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0081 0.0093
Schistosoma mansoni hypothetical protein 0.0351 0.6414 0.8419
Echinococcus granulosus importin subunit beta 1 0.0033 0.0496 0.0651
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0008 0.0039 0.0044
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0334 0.054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0081 0.0093
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0081 0.0107
Echinococcus granulosus traf and tnf receptor associated protein 0.0008 0.0039 0.0051
Echinococcus granulosus neutral sphingomyelinase 0.0008 0.0039 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.3511 0.4002
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1198 0.1885
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.1356 0.1425
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.1356 0.2142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0081 0.0093
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0008 0.004 0.0046
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0228 0.4117 0.5405
Mycobacterium tuberculosis Conserved protein 0.0079 0.1356 0.1425
Toxoplasma gondii exonuclease III APE 0.0041 0.0648 0.1982
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0081 0.0107
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0648 0.1047
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0712 0.3824
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0106 0.1862 0.2122
Brugia malayi CCR4 0.0008 0.0039 0.0044
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0602 0.0791
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0008 0.004 0.0053
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0643 0.1562
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0081 0.0107
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.039 0.063
Onchocerca volvulus 0.0016 0.0175 0.0137
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0602 0.1463
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0097 0.0111
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.004 0.0046
Entamoeba histolytica hypothetical protein 0.0027 0.0383 0.093
Loa Loa (eye worm) DOMON domain-containing protein 0.0016 0.0175 0.0199
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0008 0.004 0.0053
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0008 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0027 0.0383 0.5651
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0008 0.0039 0.0051
Trichomonas vaginalis dullard protein, putative 0.0027 0.0391 0.0391
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Trypanosoma brucei DNA polymerase eta, putative 0.0339 0.6189 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0228 0.4117 0.6632
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0712 0.2178
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0334 0.0381
Brugia malayi Muscle positioning protein 4 0.0016 0.0175 0.0199
Loa Loa (eye worm) beta-lactamase 0.0079 0.1356 0.1546
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0602 0.0973
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0081 0.0107
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0066 0.0087
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0008 0.004 0.0046
Schistosoma mansoni DNA polymerase IV / kappa 0.0071 0.1198 0.1573
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0007 0.0007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0081 0.0043
Toxoplasma gondii ABC1 family protein 0.0079 0.1356 0.4147
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0008 0.0039 0.0207
Loa Loa (eye worm) hypothetical protein 0.0017 0.0197 0.0224
Mycobacterium ulcerans beta-lactamase 0.0079 0.1356 0.2606
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0007 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0007 0.0007
Schistosoma mansoni cpg binding protein 0.0031 0.0458 0.0602
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0602 0.0602
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0039 0.0044
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0334 0.0726
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.1356 0.1356
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0094
Brugia malayi polk-prov protein 0.0071 0.1198 0.1366
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.1356 0.2606
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0602 0.0791
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Echinococcus granulosus expressed protein 0.0008 0.004 0.0053
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0027 0.0391 0.2102
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Leishmania major pantothenate kinase subunit, putative 0.0008 0.0039 0.0062
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0383 0.2057
Onchocerca volvulus 0.0008 0.004 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0081 0.0093
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0506 0.9287 1
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0008 0.004 0.0053
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0081 0.0107
Schistosoma mansoni DNA polymerase eta 0.0339 0.6189 0.8124
Onchocerca volvulus 0.0016 0.0175 0.0137
Echinococcus multilocularis expressed protein 0.0008 0.004 0.0053
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0081 0.0107
Schistosoma mansoni hypothetical protein 0.0016 0.0175 0.023
Schistosoma mansoni hypothetical protein 0.0178 0.3193 0.4191
Brugia malayi beta-lactamase 0.0079 0.1356 0.1546
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0081 0.0107
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0648 1
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0178 0.3193 0.4191
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0027 0.0391 0.0514
Schistosoma mansoni coup transcription factor 0.0011 0.0081 0.0107
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0008 0.004 0.0053
Schistosoma mansoni carbon catabolite repressor protein 0.0008 0.0039 0.0051
Schistosoma mansoni flap endonuclease-1 0.0025 0.0341 0.0448
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0081 0.0107
Onchocerca volvulus 0.0016 0.0175 0.0137
Echinococcus granulosus geminin 0.0178 0.3193 0.4191
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0081 0.0043
Leishmania major DNA polymerase eta, putative 0.0182 0.327 0.5283
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0334 0.0439
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0081 0.0093
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0094
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0334 0.0439
Leishmania major hypothetical protein, conserved 0.0008 0.0039 0.0062
Leishmania major DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.1198 0.1936
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0008 0.004 0.0053
Schistosoma mansoni importin beta-1 0.0033 0.0496 0.0651
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0496 0.1517
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0182 0.327 1
Plasmodium vivax SET domain containing protein 0.0007 0.0012 0.0064
Entamoeba histolytica G protein alpha subunit, putative 0.0008 0.004 0.0097
Mycobacterium leprae Probable lipase LipE 0.0079 0.1356 1
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0391 0.0391
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0008 0.0039 0.0051
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0094
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0712 0.0712
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0383 0.2057
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0039 0.0051
Echinococcus granulosus flap endonuclease 1 0.0027 0.039 0.0512
Trypanosoma cruzi DNA polymerase eta, putative 0.0339 0.6189 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0228 0.4117 0.4117
Schistosoma mansoni cpg binding protein 0.0029 0.0427 0.0561
Echinococcus granulosus L aminoadipate semialdehyde 0.0095 0.1657 0.2175
Schistosoma mansoni GTP-binding protein alpha subunit 0.0008 0.004 0.0053
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0039 0.0039
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.1356 0.1425
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0007 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0648 0.0659
Schistosoma mansoni ran 0.0024 0.0334 0.0439
Trypanosoma brucei RNA editing exonuclease 2 0.0008 0.0039 0.0062
Brugia malayi G-protein alpha subunit 0.0008 0.004 0.0046
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0008 0.004 0.0053
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0496 0.0801
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0648 0.1574
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0039 0.0051
Schistosoma mansoni terminal deoxycytidyl transferase 0.0228 0.4117 0.5405
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0039 0.0039
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0648 0.0648
Entamoeba histolytica deoxycytidyl transferase, putative 0.0228 0.4117 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.1169 0.1535
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.3511 0.461
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0039 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0391 0.0574
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1198 0.1885
Schistosoma mansoni ap endonuclease 0.0041 0.0648 0.0851
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0081 0.0107
Trypanosoma brucei DNA polymerase IV, putative 0.0228 0.4117 0.6653
Leishmania major hypothetical protein, conserved 0.0106 0.1862 0.3008
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0027 0.0391 0.095
Loa Loa (eye worm) hypothetical protein 0.0339 0.6189 0.7054
Plasmodium falciparum importin beta, putative 0.0033 0.0496 0.2664
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0648 0.1047
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0228 0.4117 0.5405
Mycobacterium ulcerans hypothetical protein 0.0071 0.1198 0.2183
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0712 0.0712
Giardia lamblia DINP protein human, muc B family 0.0228 0.4117 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.2699 0.3543
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.039 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0081 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0081 0.0093
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0081 0.0107
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0081 0.0043
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0008 0.0039 0.0207
Trichomonas vaginalis esterase, putative 0.0079 0.1356 0.1356
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0712 0.2178
Onchocerca volvulus 0.0069 0.1169 0.1135
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0602 0.0917
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0008 0.004 0.0053
Schistosoma mansoni synaptojanin 0.0008 0.0039 0.0051
Trypanosoma cruzi DNA polymerase kappa, putative 0.0228 0.4117 0.6632
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0648 0.3481
Trichomonas vaginalis importin beta-1, putative 0.0027 0.038 0.038
Schistosoma mansoni cpg binding protein 0.0031 0.0458 0.0602
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0228 0.4117 0.4693
Loa Loa (eye worm) hypothetical protein 0.0071 0.1198 0.1366
Plasmodium vivax exodeoxyribonuclease III, putative 0.0008 0.0039 0.0207
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.1356 0.1425
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0081 0.0107
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0071 0.1198 0.3664
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0008 0.0039 0.0062
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0383 0.5
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0008 0.0025 0.0033
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0039 0.0207
Echinococcus multilocularis cpg binding protein 0.0031 0.0458 0.0602
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0602 0.1383
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0334 0.1797
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0081 0.0093
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Schistosoma mansoni ran 0.0024 0.0334 0.0439
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0334 0.1797
Trypanosoma brucei DNA damage repair protein, putative 0.0071 0.1198 0.1936
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0081 0.0107
Trypanosoma brucei unspecified product 0.0157 0.2804 0.453
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0008 0.0039 0.0094
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.1356 0.178
Mycobacterium tuberculosis Conserved protein 0.0079 0.1356 0.1425
Mycobacterium leprae conserved hypothetical protein 0.0079 0.1356 1
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0008 0.004 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0157 0.2804 0.453
Brugia malayi hypothetical protein 0.0106 0.1862 0.2122
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0602 0.0602
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.1356 0.178
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.2699 0.3076
Trichomonas vaginalis ran, putative 0.0024 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0385 0.0439
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.004 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0008 0.004 0.0046
Loa Loa (eye worm) hypothetical protein 0.0008 0.0039 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0079 0.1356 0.7284
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.039 0.0862
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0602 0.0973
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0602 0.0687
Mycobacterium tuberculosis Conserved protein 0.0079 0.1356 0.1425
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0081 0.0107
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0648 0.0991
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0602 0.0791
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0008 0.004 0.0053
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0081 0.0107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0007 0.0007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0081 0.0107
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0383 0.1171
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.1862 0.3008
Schistosoma mansoni cript-related 0.0008 0.0039 0.0051
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0008 0.0039 0.0062
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0007 0.0007
Echinococcus granulosus MAM 0.0017 0.0197 0.0258
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0009 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0099 0.013
Trypanosoma brucei DNA polymerase IV, putative 0.0228 0.4117 0.6653
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.3511 0.4002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0081 0.0093
Loa Loa (eye worm) hypothetical protein 0.0008 0.004 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0081 0.0093
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0039 0.0062
Loa Loa (eye worm) hypothetical protein 0.0079 0.1356 0.1546
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.1111 0.1458
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0383 0.0619
Loa Loa (eye worm) hypothetical protein 0.0079 0.1356 0.1546
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0383 0.1171
Trypanosoma cruzi DNA damage repair protein, putative 0.0071 0.1198 0.1885
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.004 0.0053
Onchocerca volvulus 0.0016 0.0175 0.0137
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0228 0.4117 0.441
Leishmania major RNA-editing complex protein MP100, putative 0.0008 0.0039 0.0062
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.1356 0.1356
Leishmania major importin beta-1 subunit, putative 0.0027 0.038 0.0614
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0008 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0118
Trypanosoma cruzi DNA polymerase eta, putative 0.0182 0.327 0.5254
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0095 0.1657 0.1889
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0081 0.0093
Loa Loa (eye worm) hypothetical protein 0.0095 0.1657 0.1889
Loa Loa (eye worm) hypothetical protein 0.0008 0.0039 0.0044
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.1356 0.1425
Trypanosoma brucei DNA polymerase kappa, putative 0.0228 0.4117 0.6653
Loa Loa (eye worm) hypothetical protein 0.0079 0.1356 0.1546
Brugia malayi nuclear receptor NHR-88 0.0011 0.0081 0.0093
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0008 0.004 0.0046
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0008 0.004 0.0053
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0039 0.0207
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0771 0.1012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0602 0.0791
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0039 0.0094
Trypanosoma brucei DNA polymerase kappa, putative 0.0157 0.2804 0.453
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0081 0.0093
Onchocerca volvulus 0.0029 0.0427 0.039
Mycobacterium tuberculosis Conserved hypothetical protein 0.0228 0.4117 0.441
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.1862 0.2964
Schistosoma mansoni hypothetical protein 0.0048 0.0771 0.1012
Mycobacterium ulcerans lipase LipD 0.0079 0.1356 0.2606
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.3511 0.461
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.1862 0.2964
Schistosoma mansoni ap endonuclease 0.0041 0.0648 0.0851
Echinococcus multilocularis 0.0027 0.0391 0.0514
Echinococcus multilocularis dna polymerase kappa 0.0228 0.4117 0.5405
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0081 0.0107
Echinococcus multilocularis deoxyribonuclease 1 2 0.0008 0.0039 0.0051
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0602 0.0602
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0039 0.0062
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.004 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.3511 0.461
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0027 0.0391 0.2102
Brugia malayi beta-lactamase family protein 0.0079 0.1356 0.1546
Mycobacterium ulcerans DNA polymerase IV 0.0228 0.4117 1
Onchocerca volvulus 0.0079 0.1356 0.1323
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.1356 0.2191
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.3511 0.461
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0648 0.0851
Loa Loa (eye worm) hypothetical protein 0.0079 0.1356 0.1546
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.039 0.2095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.3511 0.461
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0228 0.4117 0.6653
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0712 0.0935
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0081 0.0107
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0008 0.0039 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0007
Loa Loa (eye worm) acetyltransferase 0.0151 0.2699 0.3076
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0008 0.004 0.004
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0496 0.0651
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0027 0.0391 0.0514
Echinococcus granulosus synaptojanin 1 0.0008 0.0039 0.0051
Plasmodium falciparum DNA repair protein REV1, putative 0.0071 0.1198 0.6436
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0039 0.0207
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0008 0.004 0.0046
Loa Loa (eye worm) hypothetical protein 0.0008 0.0039 0.0044
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0039 0.0044
Loa Loa (eye worm) hypothetical protein 0.0008 0.004 0.0046
Schistosoma mansoni hypothetical protein 0.0017 0.0197 0.0258
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Mycobacterium ulcerans DNA polymerase IV 0.0228 0.4117 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0197 0.0224
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.1862 1
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0008 0.004 0.0046
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0081 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0228 0.4117 0.6632
Plasmodium falciparum DNase I-like protein, putative 0.0008 0.0039 0.0207
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0071 0.1198 0.3664
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.1356 0.2142
Echinococcus granulosus snurportin 1 0.0351 0.6414 0.8419
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.1356 0.1356
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0008 0.004 0.004
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.039 0.1193
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0099 0.0113
Trypanosoma brucei unspecified product 0.0228 0.4117 0.6653
Trypanosoma cruzi DNA polymerase kappa, putative 0.0228 0.4117 0.6632
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0081 0.0093
Brugia malayi ecdysteroid receptor 0.0011 0.0081 0.0093
Entamoeba histolytica Ran family GTPase 0.0024 0.0334 0.0812
Echinococcus multilocularis MAM 0.0017 0.0197 0.0258
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.004 0.004
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0008 0.0039 0.0094
Loa Loa (eye worm) hypothetical protein 0.0079 0.1356 0.1546
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0351 0.6414 0.731
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.1356 0.1356
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0039 0.0044
Trypanosoma brucei chrX additional, unordered contigs 0.0071 0.1198 0.1936
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0081 0.0093
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.1862 0.5694
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.262 0.3439
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0066 0.0087
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0081 0.0107
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0081 0.0107
Echinococcus granulosus dna polymerase kappa 0.0228 0.4117 0.5405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0081 0.0093
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0008 0.0039 0.0039
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.2699 0.3543
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0081 0.0093
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0039 0.0044
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0039 0.0094
Trypanosoma brucei DNA damage repair protein, putative 0.0071 0.1198 0.1936
Brugia malayi steroid hormone receptor 0.0011 0.0081 0.0093
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.039 0.063
Echinococcus multilocularis synaptojanin 1 0.0008 0.0039 0.0051
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0027 0.0391 0.0865
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0081 0.0107
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0008 0.004 0.0053
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.1356 0.1546
Loa Loa (eye worm) hypothetical protein 0.0011 0.0081 0.0093
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0039 0.0094
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0391 0.0391
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0081 0.0093

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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