TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 350.242 | Formula: C17H17Cl2N3O
H donors: 1 H acceptors: 3 LogP: 4.75 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: CCCc1nc2c(n1Cc1cc(Cl)c(c(c1)Cl)O)nccc2C
InChi: 1S/C17H17Cl2N3O/c1-3-4-14-21-15-10(2)5-6-20-17(15)22(14)9-11-7-12(18)16(23)13(19)8-11/h5-8,23H,3-4,9H2,1-2H3
InChiKey: OTFWXOOPLLSNJX-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2077	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.1445	0.6566	0.6566
Brugia malayi	Cathepsin L-like precursor	0.1445	0.6566	0.6566
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Echinococcus granulosus	kinesin family 1	0.0846	0.3317	0.3317
Brugia malayi	Papain family cysteine protease containing protein	0.0311	0.0415	0.0415
Entamoeba histolytica	cysteine proteinase, putative	0.0771	0.2909	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0311	0.0415	0.0415
Loa Loa (eye worm)	cathepsin B	0.0857	0.338	0.338
Brugia malayi	cathepsin L precursor	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Entamoeba histolytica	cysteine proteinase, putative	0.0985	0.4073	0.5946
Schistosoma mansoni	voltage-gated potassium channel	0.0884	0.3524	0.3524
Brugia malayi	Papain family cysteine protease containing protein	0.1445	0.6566	0.6566
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0771	0.2909	0.2909
Echinococcus multilocularis	cathepsin b	0.2077	1	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0771	0.2909	0.2602
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0857	0.338	0.1287
Loa Loa (eye worm)	hypothetical protein	0.0311	0.0415	0.0415
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.1445	0.6566	1
Schistosoma mansoni	voltage-gated potassium channel	0.0884	0.3524	0.3524
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.2077	1	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0985	0.4073	0.3816
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Echinococcus granulosus	cathepsin b	0.2077	1	1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0756	0.2832	0.3928
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Trypanosoma cruzi	cysteine peptidase, putative	0.1445	0.6566	0.6417
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0771	0.2909	0.2909
Loa Loa (eye worm)	hypothetical protein	0.0311	0.0415	0.0415
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0771	0.2909	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Brugia malayi	cathepsin F-like cysteine proteinase	0.0311	0.0415	0.0415
Plasmodium vivax	vivapain-3	0.0771	0.2909	0.4054
Entamoeba histolytica	cysteine proteinase, putative	0.0771	0.2909	0.4054
Schistosoma mansoni	cathepsin s	0.046	0.1221	0.1221
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Echinococcus granulosus	cathepsin L	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Entamoeba histolytica	cysteine proteinase, putative	0.0771	0.2909	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Brugia malayi	fibroinase precursor	0.0311	0.0415	0.0415
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0311	0.0415	0.0415
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0985	0.4073	0.5946
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0311	0.0415	0.0415
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.046	0.1221	0.1221
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.1445	0.6566	0.6566
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Echinococcus granulosus	cathepsin l1	0.1445	0.6566	0.6566
Plasmodium vivax	vivapain-2	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.1445	0.6566	1
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0985	0.4073	0.4073
Leishmania major	cysteine peptidase A (CPA)	0.1445	0.6566	1
Plasmodium falciparum	cysteine proteinase falcipain 3	0.1445	0.6566	1
Onchocerca volvulus		0.1445	0.6566	1
Onchocerca volvulus		0.1445	0.6566	1
Entamoeba histolytica	cysteine proteinase, putative	0.0771	0.2909	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0311	0.0415	0.0415
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0857	0.338	0.3093
Echinococcus granulosus	cathepsin b	0.2077	1	1
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0311	0.0415	0.0415
Brugia malayi	Papain family cysteine protease containing protein	0.0311	0.0415	0.0415
Trypanosoma cruzi	cysteine peptidase, putative	0.1445	0.6566	0.6417
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.046	0.1221	0.1221
Loa Loa (eye worm)	hypothetical protein	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Brugia malayi	Cathepsin L-like precursor	0.046	0.1221	0.1221
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.081	0.3121	0.3121
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0311	0.0415	0.0415
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Brugia malayi	cathepsin L-like precursor	0.0985	0.4073	0.4073
Onchocerca volvulus		0.0985	0.4073	0.5946
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Echinococcus granulosus	cathepsin L	0.0771	0.2909	0.2909
Plasmodium vivax	unspecified product	0.046	0.1221	0.1309
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Brugia malayi	Cathepsin L-like precursor	0.1445	0.6566	0.6566
Trypanosoma cruzi	cysteine proteinase, putative	0.0771	0.2909	0.2602
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0771	0.2909	0.4054
Echinococcus granulosus	cathepsin L cysteine proteinase	0.1445	0.6566	0.6566
Plasmodium vivax	unspecified product	0.0771	0.2909	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Brugia malayi	cathepsin F-like cysteine proteinase	0.046	0.1221	0.1221
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0311	0.0415	0.0415
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0756	0.2832	0.3928
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.2077	1	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0985	0.4073	0.5946
Loa Loa (eye worm)	hypothetical protein	0.0311	0.0415	0.0415
Loa Loa (eye worm)	ctsf protein	0.1445	0.6566	0.6566
Trypanosoma cruzi	cysteine peptidase, putative	0.1445	0.6566	0.6417
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Loa Loa (eye worm)	hypothetical protein	0.0985	0.4073	0.4073
Giardia lamblia	Cathepsin B precursor	0.0857	0.338	1
Onchocerca volvulus		0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0771	0.2909	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.1445	0.6566	0.6566
Brugia malayi	Cathepsin L-like precursor	0.0985	0.4073	0.4073
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.081	0.3121	0.3121
Schistosoma mansoni	cathepsin F (C01 family)	0.0985	0.4073	0.4073
Trypanosoma cruzi	cruzipain precursor, putative	0.046	0.1221	0.084
Onchocerca volvulus		0.1445	0.6566	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.0771	0.2909	0.4054
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.1445	0.6566	0.6566
Toxoplasma gondii	cathepsin B	0.0857	0.338	0.4819
Loa Loa (eye worm)	hypothetical protein	0.0311	0.0415	0.0415
Brugia malayi	Cathepsin L-like precursor	0.1445	0.6566	0.6566
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0311	0.0415	0.0415
Echinococcus multilocularis	cathepsin L	0.0311	0.0415	0.0415
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0311	0.0415	0.0415
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2077	1	1
Loa Loa (eye worm)	hypothetical protein	0.0311	0.0415	0.0415
Brugia malayi	Papain family cysteine protease containing protein	0.0771	0.2909	0.2909
Brugia malayi	Papain family cysteine protease containing protein	0.0311	0.0415	0.0415
Echinococcus multilocularis	cathepsin L	0.0771	0.2909	0.2909
Brugia malayi	Cathepsin L-like precursor	0.1445	0.6566	0.6566
Echinococcus granulosus	cathepsin l cysteine peptidase	0.1445	0.6566	0.6566
Schistosoma mansoni	cathepsin F (C01 family)	0.1445	0.6566	0.6566
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0857	0.338	0.4819
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Brugia malayi	Cathepsin L-like precursor	0.1445	0.6566	0.6566
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2077	1	1
Echinococcus multilocularis	cysteine protease	0.1445	0.6566	0.6566
Echinococcus multilocularis	kinesin family 1	0.0846	0.3317	0.3317
Onchocerca volvulus	Cathepsin F homolog	0.1445	0.6566	1
Schistosoma mansoni	cathepsin F (C01 family)	0.1445	0.6566	0.6566
Loa Loa (eye worm)	hypothetical protein	0.0985	0.4073	0.4073
Loa Loa (eye worm)	cysteine protease	0.1445	0.6566	0.6566
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0771	0.2909	0.2602
Trypanosoma cruzi	cysteine peptidase, putative	0.1445	0.6566	0.6417
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Schistosoma mansoni	hypothetical protein	0.0736	0.2721	0.2721
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Schistosoma mansoni	cathepsin S (C01 family)	0.0311	0.0415	0.0415
Brugia malayi	Cathepsin L-like precursor	0.0985	0.4073	0.4073
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Plasmodium vivax	vivapain-1	0.0771	0.2909	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.081	0.3121	0.3121
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.1445	0.6566	1
Entamoeba histolytica	cysteine proteinase 2	0.0771	0.2909	0.4054
Schistosoma mansoni	cathepsin B (C01 family)	0.0311	0.0415	0.0415
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.1445	0.6566	0.6566
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Onchocerca volvulus		0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0311	0.0415	0.0415
Onchocerca volvulus		0.1445	0.6566	1
Echinococcus multilocularis	cathepsin b	0.2077	1	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0771	0.2909	0.2909
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Loa Loa (eye worm)	hypothetical protein	0.2077	1	1
Loa Loa (eye worm)	hypothetical protein	0.046	0.1221	0.1221
Loa Loa (eye worm)	hypothetical protein	0.046	0.1221	0.1221
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0311	0.0415	0.0415
Echinococcus granulosus	cysteine protease	0.0771	0.2909	0.2909
Echinococcus granulosus	cathepsin L cysteine protease	0.0771	0.2909	0.2909
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1445	0.6566	1
Trypanosoma cruzi	cysteine peptidase, putative	0.046	0.1221	0.084
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Entamoeba histolytica	cysteine protease, putative	0.0771	0.2909	0.4054
Entamoeba histolytica	cysteine proteinase, putative	0.1445	0.6566	1
Brugia malayi	Cathepsin L-like precursor	0.1445	0.6566	0.6566
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0857	0.338	0.338
Toxoplasma gondii	cathepsin CPL	0.1445	0.6566	1
Onchocerca volvulus	Cathepsin L homolog	0.1445	0.6566	1
Loa Loa (eye worm)	hypothetical protein	0.0985	0.4073	0.4073
Trypanosoma cruzi	cysteine peptidase, putative	0.0771	0.2909	0.2602
Schistosoma mansoni	cathepsin C	0.0311	0.0415	0.0415
Brugia malayi	cathepsin L-like cysteine proteinase	0.0311	0.0415	0.0415
Trypanosoma cruzi	cysteine protease, putative	0.0771	0.2909	0.2602
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.1445	0.6566	1
Echinococcus multilocularis	cysteine protease	0.1445	0.6566	0.6566
Trypanosoma cruzi	cruzipain precursor, putative	0.1445	0.6566	0.6417
Giardia lamblia	Cathepsin B precursor	0.0857	0.338	1
Onchocerca volvulus	Cathepsin L homolog	0.1445	0.6566	1
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.081	0.3121	0.3121
Leishmania major	cathepsin L-like protease	0.1445	0.6566	1
Onchocerca volvulus		0.1445	0.6566	1
Brugia malayi	Papain family cysteine protease containing protein	0.0771	0.2909	0.2909
Loa Loa (eye worm)	hypothetical protein	0.1445	0.6566	0.6566
Echinococcus granulosus	cathepsin l1	0.0985	0.4073	0.4073
Giardia lamblia	Cathepsin B precursor	0.0857	0.338	1
Entamoeba histolytica	cysteine proteinase, putative	0.1445	0.6566	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Loa Loa (eye worm)	hypothetical protein	0.046	0.1221	0.1221
Plasmodium vivax	vivapain-2	0.1445	0.6566	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.1445	0.6566	1
Loa Loa (eye worm)	hypothetical protein	0.0703	0.2541	0.2541
Loa Loa (eye worm)	fibroinase	0.1445	0.6566	0.6566
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.1445	0.6566	0.6566

Activities

Activity type	Activity value	Assay description	Source	Reference
ED2 (functional)	= 0.15 mg kg-1	In vivo antagonism of Angiotensin II induced dose-pressor response in male rats.	ChEMBL.	No reference
ED2 (functional)	= 0.15 mg kg-1	In vivo antagonism of Angiotensin II induced dose-pressor response in male rats.	ChEMBL.	No reference
pA2 (functional)	= 8.9	Potency of the Angiotensin II-induced contraction of rabbit aortic strips	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL70144

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 111206