Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0323 | 0.0296 |
Brugia malayi | RNA binding protein | 0.0139 | 0.454 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1456 | 0.2849 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0139 | 0.454 | 0.9807 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0015 | 0.0311 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0323 | 0.0296 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0323 | 0.0296 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Schistosoma mansoni | DNA helicase recq1 | 0.0012 | 0.0194 | 0.0428 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1395 | 0.3073 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0028 | 0.0757 | 0.1296 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1395 | 0.2763 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1456 | 0.2904 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0323 | 0.0291 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0019 | 0.0447 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0323 | 0.0296 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0028 | 0.0757 | 0.0461 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.0012 | 0.0194 | 0.0428 |
Loa Loa (eye worm) | RNA binding protein | 0.0139 | 0.454 | 0.9807 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1395 | 0.2763 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.03 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Echinococcus multilocularis | bloom syndrome protein | 0.0028 | 0.0757 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0932 | 0.1665 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0012 | 0.0194 | 0.4422 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0147 | 0.4782 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.1395 | 0.2763 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1456 | 0.2904 |
Loa Loa (eye worm) | RecQ helicase | 0.0028 | 0.0757 | 0.1271 |
Loa Loa (eye worm) | TAR-binding protein | 0.0139 | 0.454 | 0.9807 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.1395 | 0.271 |
Echinococcus granulosus | tar DNA binding protein | 0.0139 | 0.454 | 1 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0025 | 0.0641 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0323 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0323 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1456 | 0.2849 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0139 | 0.454 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0015 | 0.0311 | 0.5 |
Echinococcus granulosus | bloom syndrome protein | 0.0028 | 0.0757 | 0.1296 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0323 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.4625 | 1 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0015 | 0.0311 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Brugia malayi | TAR-binding protein | 0.0139 | 0.454 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1395 | 0.3073 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0015 | 0.0311 | 0.0311 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0012 | 0.0194 | 0.4422 |
Schistosoma mansoni | tar DNA-binding protein | 0.0139 | 0.454 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0147 | 0.4782 | 0.5 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0147 | 0.4782 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0139 | 0.454 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.03 | 1 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0323 | 0.0296 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0932 | 0.2052 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1395 | 0.3073 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0932 | 0.1697 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1395 | 0.2763 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0022 | 0.0555 | 0.1223 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0323 | 0.0296 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1395 | 0.2763 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.0439 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0323 | 0.0711 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0028 | 0.0757 | 0.0461 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.03 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.