Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0285 | 0.0599 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.003 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.2648 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0285 | 0.0822 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.1534 | 0.334 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0827 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0281 | 0.027 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0045 | 0.0394 | 0.0839 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.0066 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.0627 | 0.1351 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0285 | 0.0931 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0194 | 0.0399 |
Echinococcus multilocularis | cpg binding protein | 0.0092 | 0.098 | 0.0969 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.01 | 0.0194 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.3697 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0285 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0285 | 0.0599 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0281 | 0.0811 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.003 | 0.022 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0281 | 0.027 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.01 | 0.0089 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0086 | 0.0542 |
Echinococcus multilocularis | peregrin | 0.0028 | 0.0194 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0627 | 0.1351 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0285 | 0.0285 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0194 | 0.0194 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.01 | 0.0089 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.01 | 0.0089 |
Schistosoma mansoni | tar DNA-binding protein | 0.0266 | 0.3117 | 0.3117 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.0985 | 0.0974 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.2243 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0019 | 0.0079 | 0.0146 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0124 | 0.1372 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.01 | 0.01 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.01 | 0.0194 |
Onchocerca volvulus | 0.0087 | 0.0919 | 0.199 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.01 | 0.0194 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Schistosoma mansoni | cpg binding protein | 0.0092 | 0.098 | 0.098 |
Loa Loa (eye worm) | RNA binding protein | 0.0266 | 0.3117 | 0.6815 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.003 | 0.022 | 0.0627 |
Loa Loa (eye worm) | histone methyltransferase | 0.0027 | 0.0178 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0079 | 0.0146 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0124 | 0.1372 | 0.1362 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0124 | 0.1372 | 0.1362 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0042 | 0.0222 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0124 | 0.1372 | 0.1362 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0042 | 0.0869 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0627 | 0.0616 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0328 | 0.0694 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0328 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1077 | 0.1077 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0031 | 0.0226 | 0.0226 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.01 | 0.0089 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.003 | 0.022 | 1 |
Brugia malayi | DIX domain containing protein | 0.0019 | 0.0079 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0281 | 0.0591 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0042 | 0.0222 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0284 | 0.3331 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0266 | 0.3117 | 0.3109 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0022 | 0.0113 | 0.0101 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0285 | 0.0822 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0194 | 0.0399 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0124 | 0.1372 | 0.1362 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.01 | 0.0194 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.0066 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0285 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.01 | 0.0089 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0266 | 0.3117 | 0.6815 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0285 | 0.0931 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0019 | 0.0079 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0086 | 0.0222 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0086 | 0.2329 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0194 | 0.0826 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.01 | 0.0089 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0019 | 0.0079 | 0.0067 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0281 | 0.0281 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0019 | 0.0079 | 0.0067 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.13 | 0.2828 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0627 | 0.0627 |
Brugia malayi | CXXC zinc finger family protein | 0.0087 | 0.0919 | 0.199 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0042 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0285 | 0.0599 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0027 | 0.0178 | 0.0166 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0266 | 0.3117 | 0.6815 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.033 | 0.0318 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.01 | 0.0089 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.01 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0079 | 0.0146 |
Brugia malayi | Bromodomain containing protein | 0.0028 | 0.0194 | 0.0399 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.0627 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0139 | 0.1549 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.01 | 0.01 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.13 | 0.2828 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.0627 | 0.0616 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.01 | 0.0194 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0285 | 0.0822 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0285 | 0.0931 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.01 | 0.0194 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0079 | 0.0146 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0079 | 0.0146 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0627 | 0.0616 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.01 | 0.0089 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.3697 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.01 | 0.0194 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0194 | 0.6497 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0086 | 0.3102 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0285 | 0.0599 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0086 | 0.0222 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.003 | 0.022 | 0.7508 |
Toxoplasma gondii | hypothetical protein | 0.0019 | 0.0079 | 0.0199 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0281 | 0.0811 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.003 | 0.022 | 0.0414 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.0564 | 0.1212 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0627 | 0.0627 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0019 | 0.0079 | 0.0067 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.01 | 0.0194 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0086 | 0.0542 |
Schistosoma mansoni | cpg binding protein | 0.0092 | 0.098 | 0.098 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.01 | 0.0089 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0019 | 0.0079 | 0.0146 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.0194 | 0.0333 |
Echinococcus multilocularis | geminin | 0.0508 | 0.608 | 0.6075 |
Schistosoma mansoni | hypothetical protein | 0.0508 | 0.608 | 0.608 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0285 | 0.0822 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0285 | 0.1361 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0086 | 0.0167 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0019 | 0.0079 | 0.0067 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.13 | 0.2828 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.003 | 0.022 | 0.0969 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.01 | 0.0194 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.01 | 0.0194 |
Schistosoma mansoni | dep domain containing protein | 0.0019 | 0.0079 | 0.0079 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.01 | 0.01 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0285 | 0.0285 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0285 | 0.1361 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0124 | 0.1372 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0266 | 0.3117 | 0.3117 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0036 | 0.0287 | 0.0605 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0086 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0027 | 0.0178 | 0.0166 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0285 | 0.0931 |
Echinococcus granulosus | peregrin | 0.0028 | 0.0194 | 0.0182 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0285 | 0.0931 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0285 | 0.0822 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.0985 | 0.2135 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0328 | 0.0694 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0124 | 0.1372 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0019 | 0.0079 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0285 | 0.0599 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0281 | 0.0281 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0194 | 0.8653 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.01 | 0.0089 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0014 | 0.002 | 0.0008 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.01 | 0.0194 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0124 | 0.1372 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0285 | 0.0599 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0086 | 0.0074 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.01 | 0.0089 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0124 | 0.1372 | 0.2985 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0201 | 0.2315 | 0.5054 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.01 | 0.0194 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.01 | 0.0089 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.3183 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.3697 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.003 |
Onchocerca volvulus | 0.0036 | 0.0285 | 0.0599 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.01 | 0.0194 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0194 | 0.0399 |
Brugia malayi | TAR-binding protein | 0.0266 | 0.3117 | 0.6815 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0124 | 0.1372 | 0.1362 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0285 | 0.1824 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0285 | 0.1322 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.01 | 0.0194 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0019 | 0.0079 | 0.0079 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.01 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.01 | 0.0194 |
Schistosoma mansoni | dishevelled | 0.0019 | 0.0079 | 0.0079 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0113 | 0.123 | 0.8932 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0285 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | cpg binding protein | 0.0092 | 0.098 | 0.0969 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.0627 | 0.0616 |
Trypanosoma brucei | RNA helicase, putative | 0.01 | 0.1077 | 0.7781 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.01 | 0.01 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.0627 | 0.4394 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0086 | 0.0237 |
Schistosoma mansoni | cpg binding protein | 0.0087 | 0.0919 | 0.0919 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.01 | 0.0089 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.003 | 0.022 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0285 | 0.1824 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.01 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.2315 | 0.5054 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.01 | 0.0194 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.003 | 0.022 | 0.7508 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.01 | 0.0089 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.01 | 0.0089 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0124 | 0.1372 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0285 | 0.0599 |
Brugia malayi | Cytochrome P450 family protein | 0.0045 | 0.0394 | 0.0839 |
Brugia malayi | N-terminal motif family protein | 0.0385 | 0.4568 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.01 | 0.0194 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0285 | 0.0931 |
Schistosoma mansoni | dishevelled | 0.0019 | 0.0079 | 0.0079 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0285 | 0.0273 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.01 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0021 | 0.002 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0285 | 0.1361 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.0627 | 0.0615 |
Onchocerca volvulus | 0.0021 | 0.01 | 0.0194 | |
Onchocerca volvulus | 0.0036 | 0.0285 | 0.0599 | |
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.1534 | 0.1534 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.01 | 0.01 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0194 | 0.0182 |
Brugia malayi | 6-phosphofructokinase | 0.0113 | 0.123 | 0.2674 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0627 | 0.0627 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0086 | 0.0162 |
Schistosoma mansoni | tar DNA-binding protein | 0.0266 | 0.3117 | 0.3117 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0019 | 0.0079 | 0.0067 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0086 | 0.0222 |
Onchocerca volvulus | 0.0036 | 0.0285 | 0.0599 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0285 | 0.0931 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.01 | 0.0194 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0281 | 0.0811 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0285 | 0.0931 |
Brugia malayi | RNA binding protein | 0.0266 | 0.3117 | 0.6815 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.01 | 0.01 |
Trichomonas vaginalis | helicase, putative | 0.002 | 0.0089 | 0.0233 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0019 | 0.0079 | 0.0067 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0285 | 0.0599 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0627 | 0.0627 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0086 | 0.0086 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0627 | 0.0616 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0019 | 0.0079 | 0.0146 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0019 | 0.0079 | 0.0079 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.01 | 0.0089 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0113 | 0.123 | 0.8932 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0113 | 0.123 | 0.7823 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0139 | 0.1549 | 1 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.003 | 0.022 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0442 | 0.0944 |
Schistosoma mansoni | hypothetical protein | 0.0827 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0281 | 0.0811 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0285 | 0.0599 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0285 | 0.1361 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.01 | 0.0089 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0113 | 0.123 | 0.2674 |
Schistosoma mansoni | regulator of G protein signaling | 0.0019 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | phosphofructokinase | 0.0113 | 0.123 | 0.2674 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0285 | 0.2006 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0013 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0139 | 0.1549 | 0.5781 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0014 | 0.002 | 0.0008 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0087 | 0.0919 | 0.199 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0019 | 0.0079 | 0.0067 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0019 | 0.0079 | 0.0146 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0022 | 0.0113 | 0.0101 |
Onchocerca volvulus | 0.0019 | 0.0079 | 0.0146 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0042 | 0.0653 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.01 | 0.0194 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0284 | 0.3331 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0201 | 0.2315 | 0.5054 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.033 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0285 | 0.0599 |
Echinococcus multilocularis | tar DNA binding protein | 0.0266 | 0.3117 | 0.3109 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.003 |
Schistosoma mansoni | tar DNA-binding protein | 0.0266 | 0.3117 | 0.3117 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0113 | 0.123 | 0.2674 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0194 | 0.0826 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0285 | 0.1361 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.0627 | 0.0615 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.01 | 0.0194 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0113 | 0.123 | 0.122 |
Schistosoma mansoni | ras GTP exchange factor | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0285 | 0.0599 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0328 | 0.0317 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0086 | 0.0162 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0627 | 0.0616 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0022 | 0.0113 | 0.0101 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0113 | 0.123 | 0.123 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0086 | 0.0327 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.003 | 0.022 | 0.0414 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0267 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 0.4568 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0019 | 0.0079 | 0.0067 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | geminin | 0.0508 | 0.608 | 0.6075 |
Brugia malayi | 6-phosphofructokinase | 0.0113 | 0.123 | 0.2674 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.0985 | 0.0974 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.01 | 0.0194 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0285 | 0.0599 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.01 | 0.0089 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0285 | 0.0931 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.003 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.01 | 0.0194 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0113 | 0.123 | 0.122 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.0066 |
Brugia malayi | PHD-finger family protein | 0.0014 | 0.0021 | 0.002 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.0751 | 0.0751 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0113 | 0.123 | 0.4559 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0113 | 0.123 | 0.123 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0137 | 0.1534 | 0.334 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.0627 | 0.1351 |
Schistosoma mansoni | tar DNA-binding protein | 0.0266 | 0.3117 | 0.3117 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0201 | 0.2315 | 0.5054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0022 | 0.0113 | 0.0101 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.01 | 0.01 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.022 | 0.0627 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0113 | 0.123 | 0.748 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.01 | 0.01 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0089 | 0.0233 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.01 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0399 |
Toxoplasma gondii | 6-phosphofructokinase | 0.003 | 0.022 | 0.0969 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0165 | 0.1878 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0285 | 0.0273 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0285 | 0.2006 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 0.123 | 0.367 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.003 | 0.022 | 0.0969 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.01 | 0.01 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0089 | 0.0233 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0086 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.01 | 0.0194 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0019 | 0.0079 | 0.0146 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0185 | 0.2121 | 0.2121 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.0627 | 0.1351 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0086 | 0.0074 |
Brugia malayi | P38 map kinase family protein 2 | 0.0124 | 0.1372 | 0.2985 |
Schistosoma mansoni | hypothetical protein | 0.0508 | 0.608 | 0.608 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0019 | 0.0079 | 0.0067 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.003 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0194 | 0.0182 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0079 | 0.0146 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.01 | 0.01 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.01 | 0.01 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0042 | 0.0042 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.3331 | 1 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0113 | 0.123 | 0.3526 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0627 | 0.0627 |
Brugia malayi | phosphofructokinase | 0.0113 | 0.123 | 0.2674 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.01 | 0.0194 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0804 | 0.9723 | 0.9723 |
Schistosoma mansoni | camp-dependent rap1 guanine-nucleotide exchange factor | 0.0013 | 0.0004 | 0.0004 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0113 | 0.123 | 0.8955 |
Loa Loa (eye worm) | TAR-binding protein | 0.0266 | 0.3117 | 0.6815 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0385 | 0.4568 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | = 2 uM | Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay | ChEMBL. | 20304655 |
GI50 (functional) | = 2.9 uM | Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay | ChEMBL. | 20304655 |
GI50 (functional) | = 3.1 uM | Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay | ChEMBL. | 20304655 |
GI50 (functional) | = 3.5 uM | Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay | ChEMBL. | 20304655 |
GI50 (functional) | = 4 uM | Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay | ChEMBL. | 20304655 |
GI50 (functional) | = 5.7 uM | Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay | ChEMBL. | 20304655 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.