Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.038 | 0.0357 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.043 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.043 | 0.0425 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0138 | 0.3556 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0836 | 0.1243 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0431 | 0.0553 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0061 | 0.1154 | 0.1116 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0431 | 0.0646 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.038 | 0.0357 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0036 | 0.038 | 0.0374 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0431 | 0.0553 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0431 | 0.0514 |
Brugia malayi | RNA binding protein | 0.0207 | 0.5715 | 0.8558 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0207 | 0.5715 | 0.856 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0431 | 0.0302 |
Plasmodium falciparum | glutathione reductase | 0.0097 | 0.227 | 0.4446 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0108 | 0.2634 | 0.7202 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0431 | 0.0302 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0431 | 0.0553 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Leishmania major | cathepsin L-like protease | 0.0138 | 0.3556 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.038 | 0.056 |
Onchocerca volvulus | 0.0038 | 0.0431 | 0.0553 | |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.038 | 0.056 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0867 | 0.1837 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0054 | 0.0935 | 0.0872 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0177 | 0.4778 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0315 | 0.0117 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0315 | 0.0247 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0036 | 0.038 | 0.026 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0033 | 0.0296 | 0.0333 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0138 | 0.3556 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0431 | 0.0638 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0431 | 0.0638 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0036 | 0.038 | 0.0569 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0194 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0431 | 0.0255 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0194 |
Onchocerca volvulus | Cathepsin F homolog | 0.0036 | 0.038 | 0.0485 |
Loa Loa (eye worm) | ctsf protein | 0.0036 | 0.038 | 0.0569 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.0867 | 0.134 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0334 | 0.0376 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0867 | 0.1299 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0069 | 0.0078 |
Loa Loa (eye worm) | TAR-binding protein | 0.0207 | 0.5715 | 0.856 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0042 | 0.0557 | 0.049 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0431 | 0.0514 |
Leishmania major | cathepsin L-like protease | 0.0138 | 0.3556 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0057 | 0.1028 | 0.1539 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Toxoplasma gondii | cathepsin CPL | 0.0036 | 0.038 | 0.026 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0097 | 0.227 | 0.2216 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0033 | 0.0296 | 0.0103 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.038 | 0.0569 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0033 | 0.0296 | 0.0075 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0431 | 0.0255 |
Brugia malayi | hypothetical protein | 0.0038 | 0.043 | 0.0636 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0245 | 0.6908 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0245 | 0.6908 | 1 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.038 | 0.0357 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0061 | 0.1154 | 0.1975 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0867 | 0.134 |
Schistosoma mansoni | intermediate filament proteins | 0.0057 | 0.1028 | 0.1157 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0036 | 0.038 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0006 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0431 | 0.0646 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0296 | 0.0103 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.5715 | 0.6435 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0033 | 0.0296 | 0.0075 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0431 | 0.0255 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0177 | 0.4778 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0431 | 0.0646 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0036 | 0.038 | 0.8805 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0431 | 0.0255 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.022 | 0.6139 | 0.8843 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.038 | 0.056 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0054 | 0.0935 | 0.093 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0801 | 0.1199 |
Schistosoma mansoni | bromodomain containing protein | 0.0074 | 0.1551 | 0.1747 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0836 | 0.1243 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0431 | 0.0514 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Leishmania major | cathepsin L-like protease | 0.0138 | 0.3556 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0138 | 0.3556 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0112 |
Leishmania major | cysteine peptidase A (CPA) | 0.0036 | 0.038 | 0.0357 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0036 | 0.038 | 0.0312 |
Toxoplasma gondii | hypothetical protein | 0.0061 | 0.1154 | 0.1975 |
Loa Loa (eye worm) | RNA binding protein | 0.0207 | 0.5715 | 0.856 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0057 | 0.1028 | 0.1531 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0112 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.5715 | 0.6435 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0823 | 0.0927 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0393 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0036 | 0.038 | 0.0374 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0431 | 0.0486 |
Echinococcus granulosus | lamin | 0.0057 | 0.1028 | 0.1022 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0138 | 0.3556 | 1 |
Schistosoma mansoni | lamin | 0.0057 | 0.1028 | 0.1157 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.003 | 0.0202 | 0.0302 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0033 | 0.0296 | 0.0075 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0431 | 0.0302 |
Loa Loa (eye worm) | fibroinase | 0.0036 | 0.038 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0334 | 0.05 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0431 | 0.0364 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0194 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.038 | 0.056 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0054 | 0.0935 | 0.1053 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0061 | 0.1154 | 0.1975 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0036 | 0.038 | 0.0312 |
Echinococcus granulosus | intermediate filament protein | 0.0057 | 0.1028 | 0.1022 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0431 | 0.0553 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.038 | 0.0569 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0431 | 0.0255 |
Trypanosoma brucei | trypanothione reductase | 0.0097 | 0.227 | 0.6095 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0836 | 0.1251 |
Echinococcus multilocularis | tumor protein p63 | 0.0344 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0836 | 0.1251 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0036 | 0.038 | 0.056 |
Brugia malayi | Probable ClpP-like protease | 0.0177 | 0.4778 | 0.7154 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0431 | 0.0553 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0126 | 0.3182 | 0.8866 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0116 | 0.2873 | 0.2823 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0431 | 0.0302 |
Plasmodium vivax | vivapain-2 | 0.0036 | 0.038 | 0.026 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Echinococcus multilocularis | lamin dm0 | 0.0057 | 0.1028 | 0.0965 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0033 | 0.0296 | 0.0228 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 0.4775 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0995 | 0.149 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0069 | 0.1421 | 0.1416 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0033 | 0.0296 | 0.0051 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0295 |
Loa Loa (eye worm) | cysteine protease | 0.0036 | 0.038 | 0.0569 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.038 | 0.0485 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0054 | 0.0935 | 0.1053 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.043 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0033 | 0.0296 | 0.0103 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0431 | 0.0426 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0431 | 0.0302 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.043 | 0.0485 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0033 | 0.0296 | 0.0075 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.038 | 0.0485 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0033 | 0.0296 | 0.5 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0033 | 0.0296 | 0.0103 |
Loa Loa (eye worm) | glutathione reductase | 0.0097 | 0.227 | 0.3399 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0431 | 0.0255 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.043 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0036 | 0.038 | 0.0357 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0036 | 0.038 | 0.0312 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.022 | 0.6139 | 0.8843 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.043 | 0.0485 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0033 | 0.0296 | 0.0103 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0033 | 0.0296 | 0.029 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0033 | 0.0296 | 0.0377 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.038 | 0.0428 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0177 | 0.4778 | 0.538 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0194 |
Brugia malayi | TAR-binding protein | 0.0207 | 0.5715 | 0.8558 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0935 | 0.1401 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.038 | 0.0428 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0097 | 0.227 | 0.2265 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0116 | 0.2873 | 0.3929 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0238 | 0.6677 | 1 |
Onchocerca volvulus | 0.0271 | 0.7703 | 1 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0207 | 0.5715 | 0.5685 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0097 | 0.227 | 0.3399 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.038 | 0.056 |
Leishmania major | trypanothione reductase | 0.0097 | 0.227 | 0.6095 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0116 | 0.2873 | 0.3929 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.0867 | 0.1837 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.022 | 0.6139 | 0.8843 |
Mycobacterium tuberculosis | Probable reductase | 0.022 | 0.6139 | 0.8843 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.022 | 0.6139 | 0.8843 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0033 | 0.0296 | 0.0075 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.003 | 0.0202 | 0.0294 |
Echinococcus granulosus | cathepsin l1 | 0.0036 | 0.038 | 0.0374 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0245 | 0.6908 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0024 | 0.0006 | 0.0007 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.0867 | 0.134 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0025 | 0.0018 | 0.0018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0177 | 0.4778 | 0.6711 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0097 | 0.227 | 0.4446 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Schistosoma mansoni | lamin | 0.0057 | 0.1028 | 0.1157 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0431 | 0.0255 |
Echinococcus multilocularis | cysteine protease | 0.0036 | 0.038 | 0.0312 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0116 | 0.2873 | 0.377 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0207 | 0.5715 | 0.8558 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.5715 | 0.6435 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.043 | 1 |
Onchocerca volvulus | 0.005 | 0.0823 | 0.1061 | |
Plasmodium vivax | vivapain-2 | 0.0036 | 0.038 | 0.026 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Echinococcus granulosus | tar DNA binding protein | 0.0207 | 0.5715 | 0.5713 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0006 | 0.0009 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0032 | 0.0262 | 0.0194 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.038 | 0.8805 |
Onchocerca volvulus | 0.0057 | 0.1028 | 0.1327 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Plasmodium falciparum | thioredoxin reductase | 0.0097 | 0.227 | 0.4446 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.022 | 0.6139 | 0.8843 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0431 | 0.0375 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0431 | 0.0255 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0069 | 0.1421 | 0.1361 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0036 | 0.038 | 0.026 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0097 | 0.227 | 0.6095 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0245 | 0.6908 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0238 | 0.6677 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0108 | 0.0161 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0431 | 0.0255 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Echinococcus multilocularis | lamin | 0.0057 | 0.1028 | 0.0965 |
Brugia malayi | Thioredoxin reductase | 0.0097 | 0.227 | 0.3393 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.038 | 0.0357 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0027 | 0.0108 | 0.0102 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0431 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0823 | 0.1233 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.5715 | 0.6435 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0431 | 0.0646 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0867 | 0.1837 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0156 | 0.0224 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0276 | 0.027 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0033 | 0.0296 | 0.0075 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0256 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0042 | 0.0557 | 0.0551 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 0.4742 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0431 | 0.0646 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0033 | 0.0296 | 0.0435 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Onchocerca volvulus | 0.0038 | 0.0431 | 0.0553 | |
Trichomonas vaginalis | glutathione reductase, putative | 0.0033 | 0.0296 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0731 | 0.1095 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0069 | 0.0063 |
Brugia malayi | Isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0384 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0867 | 0.134 |
Onchocerca volvulus | 0.0057 | 0.1028 | 0.1327 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0177 | 0.4778 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0097 | 0.227 | 0.4446 |
Plasmodium falciparum | glutathione reductase | 0.0033 | 0.0296 | 0.0075 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.043 | 0.0363 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Brugia malayi | glutathione reductase | 0.0097 | 0.227 | 0.3393 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0431 | 0.0255 |
Brugia malayi | isocitrate dehydrogenase | 0.0032 | 0.0262 | 0.0384 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0431 | 0.0638 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0431 | 0.0375 |
Trichomonas vaginalis | set domain proteins, putative | 0.0271 | 0.7703 | 1 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4778 | 0.7156 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.0867 | 0.1837 |
Plasmodium vivax | glutathione reductase, putative | 0.0097 | 0.227 | 0.4446 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0116 | 0.2873 | 0.2869 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0294 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1028 | 0.1539 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0057 | 0.1028 | 0.1539 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0296 | 0.0103 |
Echinococcus granulosus | lamin dm0 | 0.0057 | 0.1028 | 0.1022 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0296 | 0.0103 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0315 | 0.0354 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0061 | 0.1154 | 0.1915 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1822 | 0.2729 |
Brugia malayi | intermediate filament protein | 0.0057 | 0.1028 | 0.1531 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0431 | 0.0646 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0097 | 0.227 | 0.3021 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0036 | 0.038 | 0.026 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0036 | 0.038 | 0.8805 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.5715 | 0.6435 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0025 | 0.0018 | 0.0018 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0334 | 0.0491 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0431 | 0.0646 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.038 | 0.0485 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.022 | 0.6139 | 0.8813 |
Brugia malayi | Bromodomain containing protein | 0.0087 | 0.1978 | 0.2956 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0315 | 0.0463 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Onchocerca volvulus | 0.0036 | 0.038 | 0.0485 | |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.038 | 0.056 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0431 | 0.0553 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0645 | 0.0966 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0315 | 0.0117 |
Echinococcus multilocularis | musashi | 0.0057 | 0.1028 | 0.0965 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0431 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0006 | 0.0009 |
Brugia malayi | Bromodomain containing protein | 0.0045 | 0.0643 | 0.0954 |
Leishmania major | cathepsin L-like protease | 0.0036 | 0.038 | 0.0357 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0027 | 0.0108 | 0.0038 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0867 | 0.1291 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0242 | 0.68 | 0.9838 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0431 | 0.0514 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0138 | 0.3556 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0315 | 0.0354 |
Echinococcus multilocularis | cysteine protease | 0.0036 | 0.038 | 0.0312 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0033 | 0.0296 | 0.0103 |
Onchocerca volvulus | 0.0034 | 0.0315 | 0.0401 | |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0177 | 0.4778 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0431 | 0.0486 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0033 | 0.0296 | 0.0075 |
Onchocerca volvulus | 0.0038 | 0.0431 | 0.0553 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antibacterial activity against Escherichia coli DH5[alpha] at 50 uM after 23 hrs by broth dilution assay | ChEMBL. | 20219378 | |
Activity (functional) | Antibacterial activity against Escherichia coli DH5[alpha] at 100 uM after 23 hrs by broth dilution assay | ChEMBL. | 20219378 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.