Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.297 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.297 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.1907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.297 | 0.297 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.1736 | 0.5844 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.297 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1907 | 0.1907 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.297 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.297 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1907 | 0.1907 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1907 | 0.1907 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.297 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.1907 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.297 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.1736 | 0.5844 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.1907 | 0.6421 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.1736 | 0.5844 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 1 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1907 | 0.1907 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.297 | 0.297 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.297 | 0.297 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.297 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.297 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0072 | 1 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.297 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.297 | 1 |
Toxoplasma gondii | propionate-CoA ligase | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.297 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.1907 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.297 | 0.297 |
Onchocerca volvulus | 0.0027 | 0.297 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1907 | 0.1907 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.297 | 0.297 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 1 | 1 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0008 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.1736 | 0.5844 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.297 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.297 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.297 | 0.297 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.1907 | 0.6421 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.297 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 1 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.