Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | importin-beta 2, putative | 0.0032 | 0.0292 | 0.1685 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0096 | 0.1691 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0096 | 0.1691 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0096 | 0.1691 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.1214 | 0.6993 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0991 | 0.1333 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0201 | 0.4017 | 0.5596 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0194 | 0.0563 |
Loa Loa (eye worm) | carboxylesterase | 0.0201 | 0.4017 | 0.5624 |
Echinococcus multilocularis | neuroligin | 0.0034 | 0.0333 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Schistosoma mansoni | pol-related | 0.0096 | 0.1691 | 0.2319 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0028 | 0.0194 | 0.0563 |
Loa Loa (eye worm) | oxidoreductase | 0.0096 | 0.1691 | 0.2368 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0096 | 0.1693 | 0.3837 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0028 | 0.0194 | 0.0216 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0201 | 0.4017 | 0.5624 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0074 | 0.1214 | 0.104 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0028 | 0.0194 | 0.0563 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0486 | 0.0922 |
Plasmodium falciparum | importin beta, putative | 0.0032 | 0.0292 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0028 | 0.0194 | 0.0563 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | ran | 0.0024 | 0.0105 | 0.0084 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Onchocerca volvulus | 0.0096 | 0.1691 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.1214 | 0.6993 |
Giardia lamblia | Aldose reductase | 0.0096 | 0.1691 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 0.1139 | 0.1541 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Loa Loa (eye worm) | oxidoreductase | 0.0096 | 0.1691 | 0.2368 |
Toxoplasma gondii | aldo-keto reductase | 0.0028 | 0.0194 | 0.0563 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0096 | 0.1691 | 0.3832 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1214 | 0.17 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0211 | 0.4244 | 0.5943 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0074 | 0.1214 | 0.6814 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.1693 | 0.2322 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0032 | 0.0292 | 0.0347 |
Onchocerca volvulus | 0.0096 | 0.1691 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1214 | 0.17 |
Echinococcus granulosus | acetylcholinesterase | 0.0201 | 0.4017 | 0.5596 |
Echinococcus multilocularis | acetylcholinesterase | 0.0201 | 0.4017 | 0.5596 |
Echinococcus multilocularis | acetylcholinesterase | 0.0201 | 0.4017 | 0.5596 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0201 | 0.4017 | 0.5596 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0096 | 0.1691 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0343 | 0.7142 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0028 | 0.0194 | 0.021 |
Loa Loa (eye worm) | oxidoreductase | 0.0096 | 0.1691 | 0.2368 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0096 | 0.1691 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1214 | 0.17 |
Echinococcus granulosus | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0028 | 0.0194 | 0.0563 |
Onchocerca volvulus | 0.0096 | 0.1691 | 1 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0096 | 0.1693 | 0.237 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Onchocerca volvulus | 0.0034 | 0.0333 | 0.0926 | |
Schistosoma mansoni | importin beta-1 | 0.0032 | 0.0292 | 0.0347 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.1693 | 0.2322 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.1139 | 0.1541 |
Echinococcus granulosus | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0074 | 0.1214 | 0.104 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0034 | 0.0333 | 0.0405 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0034 | 0.0333 | 0.0405 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0028 | 0.0194 | 0.0563 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.4017 | 0.5624 |
Echinococcus granulosus | neuroligin | 0.0034 | 0.0333 | 0.0405 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0333 | 0.0551 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0074 | 0.1214 | 0.1647 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0034 | 0.0333 | 0.0926 |
Echinococcus granulosus | acetylcholinesterase | 0.0201 | 0.4017 | 0.5596 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.1214 | 0.6814 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 0.1139 | 0.1595 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.007 | 0.0098 |
Echinococcus multilocularis | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Leishmania major | prostaglandin f synthase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.1139 | 0.1541 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0074 | 0.1214 | 0.268 |
Loa Loa (eye worm) | beta-lactamase | 0.0074 | 0.1214 | 0.17 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0028 | 0.0194 | 0.021 |
Echinococcus multilocularis | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0333 | 0.0551 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0074 | 0.1214 | 0.104 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0028 | 0.0194 | 0.0563 |
Brugia malayi | NADH-dependent xylose reductase | 0.0028 | 0.0194 | 0.0216 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0115 | 0.0099 |
Brugia malayi | Carboxylesterase family protein | 0.0201 | 0.4017 | 0.945 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0158 | 0.0334 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 0.1139 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.4017 | 0.5624 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1691 | 0.2368 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0158 | 0.0334 |
Onchocerca volvulus | 0.0074 | 0.1214 | 0.6814 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.1693 | 0.2322 |
Onchocerca volvulus | 0.0096 | 0.1691 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Brugia malayi | RNA, U transporter 1 | 0.0091 | 0.1597 | 0.3605 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.007 | 0.0035 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0096 | 0.1691 | 0.1527 |
Loa Loa (eye worm) | oxidoreductase | 0.0096 | 0.1691 | 0.2368 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0096 | 0.1691 | 0.3832 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 0.1139 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0544 | 0.0761 |
Echinococcus granulosus | snurportin 1 | 0.0343 | 0.7142 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0431 | 0.0543 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.1214 | 0.6993 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0034 | 0.0333 | 0.1437 |
Brugia malayi | TAR-binding protein | 0.0071 | 0.1139 | 0.2499 |
Loa Loa (eye worm) | oxidoreductase | 0.0096 | 0.1691 | 0.2368 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0096 | 0.1691 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | ran | 0.0024 | 0.0105 | 0.0084 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1214 | 0.17 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0028 | 0.0194 | 0.4777 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.1214 | 0.104 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0074 | 0.1214 | 0.17 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.1214 | 0.6993 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1214 | 0.17 |
Onchocerca volvulus | 0.0074 | 0.1214 | 0.6814 | |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0158 | 0.0334 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0096 | 0.1691 | 1 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0105 | 0.0084 |
Trypanosoma brucei | prostaglandin f synthase | 0.0096 | 0.1691 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.1214 | 0.6993 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0034 | 0.0333 | 0.0141 |
Brugia malayi | follicle stimulating hormone receptor | 0.0211 | 0.4244 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0343 | 0.7142 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0068 | 0.1081 | 0.5922 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.1214 | 0.104 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.1693 | 0.2322 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0028 | 0.0194 | 0.4777 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0158 | 0.0334 |
Schistosoma mansoni | gliotactin | 0.0034 | 0.0333 | 0.0405 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0028 | 0.0194 | 0.0563 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0158 | 0.0334 |
Giardia lamblia | Aldose reductase | 0.0096 | 0.1691 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0074 | 0.1214 | 0.104 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.1214 | 0.268 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0158 | 0.0334 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.1351 | 0.3012 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0028 | 0.0194 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1214 | 0.17 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0105 | 0.0084 |
Toxoplasma gondii | ABC1 family protein | 0.0074 | 0.1214 | 0.6993 |
Onchocerca volvulus | 0.0034 | 0.0333 | 0.0926 | |
Brugia malayi | RNA binding protein | 0.0071 | 0.1139 | 0.2499 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0333 | 0.0551 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0034 | 0.0333 | 0.0405 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0431 | 0.0543 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0105 | 0.0147 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0115 | 0.0099 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0028 | 0.0194 | 0.0563 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.1214 | 0.1647 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0034 | 0.0333 | 0.0405 |
Schistosoma mansoni | potassium channel beta | 0.0028 | 0.0194 | 0.021 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.1214 | 0.104 |
Brugia malayi | beta-lactamase | 0.0074 | 0.1214 | 0.268 |
Mycobacterium leprae | conserved hypothetical protein | 0.0074 | 0.1214 | 0.6814 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.1214 | 0.1647 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Entamoeba histolytica | aldose reductase, putative | 0.0096 | 0.1691 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0991 | 0.1333 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0096 | 0.1691 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0201 | 0.4017 | 0.945 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.1693 | 0.2322 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0589 | 0.0824 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.1214 | 0.268 |
Brugia malayi | Importin beta-1 subunit | 0.0032 | 0.0292 | 0.0452 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.1139 | 0.1541 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0096 | 0.1691 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0074 | 0.1214 | 0.6993 |
Trypanosoma cruzi | aldo-keto reductase | 0.0096 | 0.1691 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0074 | 0.1214 | 0.104 |
Plasmodium vivax | hypothetical protein, conserved | 0.0074 | 0.1214 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.0032 | 0.0292 | 0.0347 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0028 | 0.0194 | 0.0563 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0292 | 0.0408 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.1139 | 0.1541 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0333 | 0.0466 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 0.1139 | 0.1541 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 0.1139 | 0.1595 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.1214 | 0.6993 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1251 | 0.1751 |
Onchocerca volvulus | 0.0096 | 0.1691 | 1 | |
Entamoeba histolytica | aldose reductase, putative | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0028 | 0.0194 | 0.021 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0034 | 0.0333 | 0.0141 |
Schistosoma mansoni | aldo-keto reductase | 0.0096 | 0.1691 | 0.2319 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Onchocerca volvulus | 0.0096 | 0.1691 | 1 | |
Echinococcus granulosus | aldehyde reductase | 0.0068 | 0.1081 | 0.1459 |
Onchocerca volvulus | 0.0034 | 0.0333 | 0.0926 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.1214 | 0.6993 |
Echinococcus multilocularis | snurportin 1 | 0.0343 | 0.7142 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.0028 | 0.0194 | 0.0805 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.1214 | 0.6993 |
Onchocerca volvulus | 0.0074 | 0.1214 | 0.6814 | |
Echinococcus granulosus | hypothetical protein | 0.0096 | 0.1691 | 0.2319 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0333 | 0.0466 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0074 | 0.1214 | 0.1647 |
Leishmania major | aldo-keto reductase-like protein | 0.0096 | 0.1691 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.1075 | 0.1452 |
Mycobacterium ulcerans | beta-lactamase | 0.0074 | 0.1214 | 0.6814 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0028 | 0.0194 | 0.0805 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0333 | 0.0405 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0096 | 0.1691 | 0.3832 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0488 | 0.0683 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0034 | 0.0333 | 0.1437 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0115 | 0.0099 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0292 | 0.1178 |
Echinococcus multilocularis | aldehyde reductase | 0.0068 | 0.1081 | 0.1459 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.1693 | 0.2322 |
Toxoplasma gondii | aldose reductase, putative | 0.0096 | 0.1691 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0333 | 0.0466 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.0171 | 0.016 |
Mycobacterium ulcerans | lipase LipD | 0.0074 | 0.1214 | 0.6814 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0096 | 0.1691 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0096 | 0.1691 | 0.2319 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0096 | 0.1691 | 0.3832 |
Echinococcus multilocularis | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Schistosoma mansoni | aldo-keto reductase | 0.0096 | 0.1691 | 0.2319 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0032 | 0.0292 | 0.1178 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Onchocerca volvulus | 0.0034 | 0.0333 | 0.0926 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0096 | 0.1691 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0201 | 0.4017 | 0.5596 |
Onchocerca volvulus | 0.0034 | 0.0333 | 0.0926 | |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0028 | 0.0194 | 0.0563 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0333 | 0.0551 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0034 | 0.0333 | 0.0405 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0096 | 0.1691 | 0.2319 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0074 | 0.1214 | 0.6814 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0074 | 0.1214 | 0.6814 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.1214 | 0.6993 |
Echinococcus multilocularis | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.1139 | 0.1541 |
Echinococcus granulosus | aldo keto reductase | 0.0096 | 0.1691 | 0.2319 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0028 | 0.0194 | 0.0563 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0034 | 0.0333 | 0.0141 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0074 | 0.1214 | 0.104 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0292 | 0.1178 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.1693 | 0.2322 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0333 | 0.0551 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0074 | 0.1214 | 0.104 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0096 | 0.1691 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Log IC50 (binding) | = -1.17 uM | Binding affinity against sigma receptor | ChEMBL. | 2824774 |
Log IC50 (binding) | = -0.88 uM | Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]-spiperone | ChEMBL. | 2824774 |
Log IC50 (binding) | = -0.56 uM | Binding affinity against sigma receptor | ChEMBL. | 2824774 |
Log IC50 (binding) | = -0.37 uM | Binding affinity against sigma receptor | ChEMBL. | 2824774 |
Log IC50 (binding) | = -0.19 uM | Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]-spiperone | ChEMBL. | 2824774 |
Log IC50 (binding) | = 1.04 uM | Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]-spiperone | ChEMBL. | 2824774 |
Log kw | = 0.17 | Apparent lipophilicity (log kw) at pH 7.5 | ChEMBL. | 2824774 |
Log kw | = 0.34 | Apparent lipophilicity (log kw) at pH 7.5 | ChEMBL. | 2824774 |
pED50 (functional) | = -1.7 uM kg-1 | In vivo presynaptic dopaminergic potency, determined by the ability to reduce the accumulation of DOPA by 50% | ChEMBL. | 2824774 |
pED50 (functional) | = 0.21 uM kg-1 | In vivo presynaptic dopaminergic potency, determined by the ability to reduce the accumulation of DOPA by 50% | ChEMBL. | 2824774 |
Selectivity (binding) | = -1.6 | Selectivity of the compound pIC50 (sigma)-pIC50(D2) | ChEMBL. | 2824774 |
Selectivity (binding) | = -0.29 | Selectivity of the compound pIC50 (sigma)-pIC50(D2) | ChEMBL. | 2824774 |
Selectivity (binding) | = -0.18 | Selectivity of the compound pIC50 (sigma)-pIC50(D2) | ChEMBL. | 2824774 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.