Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0038 | 0.0445 | 0.1219 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.2429 | 0.6648 |
Plasmodium vivax | vivapain-2 | 0.0034 | 0.0357 | 0.8026 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0079 | 0.1356 | 0.4017 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0079 | 0.1356 | 0.3712 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0445 | 0.1219 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0474 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0079 | 0.1356 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0034 | 0.0357 | 0.8026 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.3654 | 0.3581 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0079 | 0.1356 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.3654 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0945 | 0.2203 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0079 | 0.1356 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0079 | 0.1356 | 0.3712 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0945 | 0.2586 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0079 | 0.1356 | 0.4017 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0079 | 0.1356 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0079 | 0.1356 | 0.4017 |
Mycobacterium leprae | putative cytochrome p450 | 0.0079 | 0.1356 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0034 | 0.0357 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0357 | 0.0357 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0079 | 0.1356 | 0.4017 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0038 | 0.0445 | 0.0445 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0945 | 0.5881 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0184 | 0.3654 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0034 | 0.0357 | 0.0978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0034 | 0.0357 | 0.0247 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0034 | 0.0357 | 0.0247 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Onchocerca volvulus | Cathepsin L homolog | 0.0034 | 0.0357 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0023 | 0.0114 | 0.0311 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0079 | 0.1356 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0357 | 0.0357 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0034 | 0.0357 | 0.0357 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0079 | 0.1356 | 0.3712 |
Brugia malayi | cytochrome P450 | 0.0079 | 0.1356 | 0.1356 |
Echinococcus granulosus | cathepsin l1 | 0.0023 | 0.0114 | 0.0311 |
Toxoplasma gondii | exonuclease III APE | 0.0038 | 0.0445 | 0.088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0079 | 0.1356 | 0.5 |
Trypanosoma brucei | cytochrome P450, putative | 0.0141 | 0.2713 | 0.7425 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0945 | 0.2203 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0357 | 0.0357 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0079 | 0.1356 | 0.3712 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0445 | 0.1219 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0945 | 0.2586 |
Onchocerca volvulus | Cathepsin F homolog | 0.0034 | 0.0357 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0079 | 0.1356 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0038 | 0.0445 | 0.1219 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0038 | 0.0445 | 0.1219 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0079 | 0.1356 | 0.4017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0184 | 0.3654 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0023 | 0.0114 | 0.0311 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0079 | 0.1356 | 0.4017 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0141 | 0.2713 | 0.7425 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0945 | 0.2586 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0079 | 0.1356 | 0.4017 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0117 | 0.2185 | 0.5981 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0128 | 0.2429 | 0.6648 |
Plasmodium vivax | vivapain-2 | 0.0034 | 0.0357 | 0.8026 |
Leishmania major | cytochrome p450-like protein | 0.0141 | 0.2713 | 0.7146 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0034 | 0.0357 | 0.0978 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0445 | 0.1219 |
Brugia malayi | Cytochrome P450 family protein | 0.0141 | 0.2713 | 0.2713 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0357 | 0.0357 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.2429 | 0.6648 |
Loa Loa (eye worm) | cysteine protease | 0.0034 | 0.0357 | 0.0247 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0034 | 0.0357 | 0.0978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0079 | 0.1356 | 0.4017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Brugia malayi | Cytochrome P450 family protein | 0.0216 | 0.4347 | 0.4347 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0023 | 0.0114 | 0.0311 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0079 | 0.1356 | 0.4017 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0038 | 0.0445 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0079 | 0.1356 | 0.303 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0079 | 0.1356 | 0.4017 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0079 | 0.1356 | 0.4017 |
Echinococcus multilocularis | 0.0079 | 0.1356 | 0.3712 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0079 | 0.1356 | 0.4017 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0079 | 0.1356 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0141 | 0.2713 | 0.2713 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0079 | 0.1356 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0445 | 0.1219 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0079 | 0.1356 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0038 | 0.0445 | 0.5 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0038 | 0.0445 | 0.0267 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0184 | 0.3654 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.2429 | 0.6284 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0034 | 0.0357 | 0.0978 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0357 | 0.0357 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0079 | 0.1356 | 0.4017 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0945 | 0.2203 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0184 | 0.3654 | 1 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0079 | 0.1356 | 0.4017 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0023 | 0.0114 | 0.0311 |
Entamoeba histolytica | cysteine protease, putative | 0.0034 | 0.0357 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0079 | 0.1356 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0141 | 0.2713 | 0.7425 |
Echinococcus multilocularis | cysteine protease | 0.0034 | 0.0357 | 0.0978 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0445 | 0.1219 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0141 | 0.2713 | 0.2629 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0079 | 0.1356 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Echinococcus granulosus | cathepsin l1 | 0.0034 | 0.0357 | 0.0978 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0034 | 0.0357 | 0.0978 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0184 | 0.3654 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0184 | 0.3654 | 0.3654 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0184 | 0.3654 | 1 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0184 | 0.3654 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0445 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0038 | 0.0445 | 0.0335 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0079 | 0.1356 | 0.4017 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0184 | 0.3654 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0034 | 0.0357 | 0.0247 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0079 | 0.1356 | 0.303 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0977 | 0.0873 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0079 | 0.1356 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0023 | 0.0114 | 0.0114 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0184 | 0.3654 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0079 | 0.1356 | 0.4017 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0079 | 0.1356 | 0.4017 |
Loa Loa (eye worm) | cytochrome P450 | 0.0079 | 0.1356 | 0.1257 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0079 | 0.1356 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0034 | 0.0357 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0079 | 0.1356 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0079 | 0.1356 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0141 | 0.2713 | 0.2629 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0357 | 0.0247 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0079 | 0.1356 | 0.4017 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0079 | 0.1356 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.2429 | 0.6284 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Leishmania major | cytochrome p450-like protein | 0.0079 | 0.1356 | 0.303 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0079 | 0.1356 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0141 | 0.2713 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0079 | 0.1356 | 1 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0184 | 0.3654 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0079 | 0.1356 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0945 | 0.1782 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0023 | 0.0114 | 0.0114 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Brugia malayi | Cathepsin L-like precursor | 0.0023 | 0.0114 | 0.0114 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0034 | 0.0357 | 0.8026 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0023 | 0.0114 | 0.0114 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0184 | 0.3654 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0079 | 0.1356 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0445 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0034 | 0.0357 | 0.8026 |
Echinococcus multilocularis | cysteine protease | 0.0034 | 0.0357 | 0.0978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0079 | 0.1356 | 0.3712 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0034 | 0.0357 | 0.0978 |
Loa Loa (eye worm) | ctsf protein | 0.0034 | 0.0357 | 0.0247 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.1356 | 0.3712 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.2429 | 0.6284 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0079 | 0.1356 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0945 | 0.2586 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0101 | 0.1828 | 0.5002 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.2429 | 0.6648 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0184 | 0.3654 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0079 | 0.1356 | 0.1356 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.2429 | 0.6648 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0079 | 0.1356 | 0.4017 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0184 | 0.3654 | 1 |
Onchocerca volvulus | 0.0034 | 0.0357 | 1 | |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0216 | 0.4347 | 0.4282 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0079 | 0.1356 | 0.4017 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0141 | 0.2713 | 0.2629 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0184 | 0.3654 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0184 | 0.3654 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0945 | 0.5484 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0038 | 0.0445 | 0.1219 |
Schistosoma mansoni | cytochrome P450 | 0.0079 | 0.1356 | 0.3712 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0445 | 0.1219 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0357 | 0.0357 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0184 | 0.3654 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | = 1 uM | Cytotoxicity against human MT4 cells after 96 hrs by MTT assay | ChEMBL. | 20359898 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.