Detailed information for compound 112160

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 396.172 | Formula: C6H14Cl2N2OPt++
  • H donors: 3 H acceptors: 1 LogP: 1.3 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1CCC2C(C1)[NH2+][Pt]([NH2+]2)(Cl)Cl
  • InChi: 1S/C6H14N2O.2ClH.Pt/c7-5-2-1-4(9)3-6(5)8;;;/h4-6,9H,1-3,7-8H2;2*1H;/q;;;+4/p-2
  • InChiKey: HSNQSSGKQWCXRH-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0304 0.045 0.045
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0132 0.0316
Trypanosoma cruzi heat shock protein 90, putative 0.0114 0.0125 0.2563
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0369 0.7542
Echinococcus granulosus neuropeptide receptor 0.0475 0.0741 0.1157
Echinococcus granulosus voltage gated potassium channel 0.0175 0.0228 0.0356
Schistosoma mansoni hypothetical protein 0.0475 0.0741 0.0741
Plasmodium falciparum plasmepsin V 0.0045 0.0007 0.0137
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0114 0.0125 0.0299
Loa Loa (eye worm) voltage-gated potassium channel 0.0175 0.0228 0.0518
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0009 0.0182
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0006 0.0009
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0304 0.045 0.0702
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0085 0.0074 0.0138
Schistosoma mansoni hypothetical protein 0.0592 0.0941 0.0941
Schistosoma mansoni opsin-like receptor 0.0475 0.0741 0.0741
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0475 0.0741 0.1157
Echinococcus multilocularis cyclin B3 1 0.0048 0.0011 0.0018
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0114 0.2236
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0164 0.021 0.0389
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Echinococcus multilocularis neuropeptide receptor 0.3786 0.6406 1
Brugia malayi mbt repeat family protein 0.0073 0.0055 0.0101
Brugia malayi aspartic protease BmAsp-2, identical 0.0045 0.0007 0.0012
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0073 0.0055 0.0124
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0114 0.0125 0.2563
Echinococcus multilocularis short transient receptor potential channel 6 0.0085 0.0074 0.0116
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Echinococcus granulosus cyclin B 0.0091 0.0085 0.0133
Schistosoma mansoni cathepsin D (A01 family) 0.0566 0.0897 0.0897
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Loa Loa (eye worm) MBCTL1 0.0084 0.0072 0.0163
Plasmodium falciparum serine/threonine protein kinase, putative 0.0326 0.0487 1
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Echinococcus granulosus tm gpcr rhodopsin 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0085 0.0074 0.0074
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0114 0.0114
Echinococcus granulosus potassium voltage gated channel protein 0.0175 0.0228 0.0356
Loa Loa (eye worm) LGC-31 protein 0.0304 0.045 0.1022
Echinococcus granulosus voltage gated potassium channel 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0143 0.0174 0.0396
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0517 0.0813 0.1847
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0175 0.0228 0.0356
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0085 0.0074 0.0116
Echinococcus granulosus nAChR subunit 0.0304 0.045 0.0702
Echinococcus granulosus TRP transient receptor potential channel 0.0085 0.0074 0.0116
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.009 0.0083 0.0188
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0304 0.045 0.0836
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.0074 0.0074
Plasmodium falciparum membrane associated erythrocyte binding-like protein 0.0065 0.0041 0.0837
Echinococcus granulosus hypothetical protein 0.0475 0.0741 0.1157
Trichomonas vaginalis cyclins, putative 0.0091 0.0085 0.1652
Onchocerca volvulus 0.014 0.0169 0.2082
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0091 0.0085 0.1756
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0057 0.0027 0.0547
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0082 0.0068 0.5
Echinococcus granulosus shaker cognate 0.0175 0.0228 0.0356
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0475 0.0741 0.1684
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Schistosoma mansoni glutamate receptor NMDA 0.0268 0.0388 0.0388
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.014 0.0169 0.0384
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0192 0.0257 0.0402
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0048 0.0011 0.0018
Brugia malayi Furin-like cysteine rich region family protein 0.0304 0.0449 0.0835
Echinococcus multilocularis fmrfamide receptor 0.0475 0.0741 0.1157
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.014 0.0169 0.0315
Leishmania major hypothetical protein, conserved 0.009 0.0083 0.1704
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.0112 0.0121 0.0274
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.0074 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0369 0.7542
Plasmodium vivax aspartyl protease, putative 0.0045 0.0007 0.0137
Schistosoma mansoni neuropeptide receptor 0.0475 0.0741 0.0741
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0475 0.0741 0.0741
Brugia malayi hypothetical protein 0.0085 0.0074 0.0138
Trypanosoma brucei btb/poz domain containing protein, putative 0.009 0.0083 0.1599
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0084 0.0072 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0084 0.0072 0.0112
Echinococcus multilocularis shaker cognate 0.0175 0.0228 0.0356
Schistosoma mansoni neurotransmitter gated ion channel 0.0164 0.021 0.021
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0091 0.0085 0.0194
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0114 0.0125 0.0195
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0475 0.0741 0.1157
Loa Loa (eye worm) ion channel NompC 0.0085 0.0074 0.0168
Echinococcus granulosus biogenic amine 5HT receptor 0.0475 0.0741 0.1157
Toxoplasma gondii apical membrane antigen 1 domain-containing protein 0.0276 0.0402 0.8257
Giardia lamblia Cyclin A 0.0048 0.0011 0.0112
Schistosoma mansoni potassium channel tetramerization domain-containing 0.009 0.0083 0.0083
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0028 0.0028
Schistosoma mansoni neuropeptide receptor 0.0475 0.0741 0.0741
Onchocerca volvulus 0.0475 0.0741 0.9118
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0592 0.0941 0.1749
Trichomonas vaginalis AGC family protein kinase 0.0326 0.0487 1
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0326 0.0487 0.076
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0108 0.0114 0.2236
Brugia malayi Protein kinase domain containing protein 0.0043 0.0003 0.0005
Echinococcus granulosus hypothetical protein 0.0085 0.0074 0.0116
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0085 0.0074 0.0168
Brugia malayi Cytochrome P450 family protein 0.0048 0.0011 0.002
Schistosoma mansoni tyrosine kinase 0.0097 0.0095 0.0095
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0048 0.0011 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Echinococcus granulosus tm gpcr rhodopsin 0.0475 0.0741 0.1157
Echinococcus granulosus peptide allatostatin:somatostatin 0.0475 0.0741 0.1157
Onchocerca volvulus 0.0447 0.0694 0.8534
Plasmodium falciparum plasmepsin VIII, putative 0.0045 0.0007 0.0137
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis BTB:POZ domain containing protein 0.009 0.0083 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Echinococcus granulosus sodium leak channel non selective protein 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.1278 0.2116 0.4806
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Giardia lamblia Hypothetical protein 0.0048 0.0011 0.0112
Trichomonas vaginalis heat shock protein, putative 0.006 0.0031 0.0519
Echinococcus granulosus sex peptide receptor 0.0475 0.0741 0.1157
Toxoplasma gondii transporter, cation channel family protein 0.0085 0.0074 0.1523
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.0074 0.0074
Plasmodium vivax K+ channel tetramerisation domain containing protein 0.009 0.0083 0.1704
Trypanosoma brucei btb/poz domain containing protein, putative 0.009 0.0083 0.1599
Brugia malayi Protein kinase domain containing protein 0.0396 0.0607 0.1128
Schistosoma mansoni neuropeptide f receptor 76f 0.0475 0.0741 0.0741
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Echinococcus granulosus cyclins 0.0048 0.0011 0.0018
Brugia malayi Eukaryotic aspartyl protease family protein 0.0045 0.0007 0.0012
Echinococcus multilocularis neuropeptide FF receptor 2 0.0475 0.0741 0.1157
Echinococcus granulosus histone acetyltransferase MYST2 0.0084 0.0072 0.0112
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0304 0.045 0.0702
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Toxoplasma gondii apical membrane antigen 1 protein 0.0065 0.0041 0.0837
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.0074 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0085 0.0074 0.0116
Echinococcus granulosus Dipeptidyl peptidase 9 0.0057 0.0027 0.0042
Schistosoma mansoni growth hormone secretagogue receptor 0.0475 0.0741 0.0741
Schistosoma mansoni adenoreceptor 0.0475 0.0741 0.0741
Echinococcus granulosus glutamate receptor 2 0.0048 0.0011 0.0018
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.017 0.0219 0.0343
Loa Loa (eye worm) mbt repeat family protein 0.0073 0.0055 0.0124
Loa Loa (eye worm) ryanodine receptor 0.0085 0.0074 0.0168
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.0074 0.0116
Onchocerca volvulus 0.0085 0.0074 0.0912
Echinococcus multilocularis neuropeptides capa receptor 0.0475 0.0741 0.1157
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0085 0.0074 0.0138
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.0074 0.0116
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0085 0.0074 0.0912
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0085 0.0074 0.0138
Loa Loa (eye worm) hypothetical protein 0.0592 0.0941 0.2138
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.009 0.0083 0.0188
Loa Loa (eye worm) latrophilin receptor protein 2 0.0592 0.0941 0.2138
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0475 0.0741 0.1377
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0006 0.0014
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.0074 0.0074
Schistosoma mansoni transient receptor potential channel 0.0085 0.0074 0.0074
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0475 0.0741 0.1157
Echinococcus granulosus cyclin b3 0.0048 0.0011 0.0018
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0447 0.0694 0.0694
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0475 0.0741 0.1157
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Loa Loa (eye worm) pigment dispersing factor receptor c 0.2615 0.4402 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Onchocerca volvulus 0.0447 0.0694 0.8534
Plasmodium vivax plasmepsin IV, putative 0.0192 0.0257 0.5289
Loa Loa (eye worm) hypothetical protein 0.0045 0.0007 0.0015
Schistosoma mansoni protein kinase 0.0326 0.0487 0.0487
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0085 0.0074 0.0138
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.009 0.0083 0.0083
Entamoeba histolytica protein kinase, putative 0.0326 0.0487 1
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Plasmodium falciparum plasmepsin VI 0.0192 0.0257 0.5289
Trichomonas vaginalis heat shock protein, putative 0.0114 0.0125 0.2469
Trichomonas vaginalis cyclin B, putative 0.0091 0.0085 0.1652
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Onchocerca volvulus 0.0475 0.0741 0.9118
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0475 0.0741 0.0741
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0189 0.0252 0.0393
Plasmodium falciparum cyclin 0.0048 0.0011 0.0235
Plasmodium falciparum heat shock protein 90 0.0134 0.0159 0.3258
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.014 0.0169 0.0315
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0085 0.0074 0.0116
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0085 0.0074 0.0912
Schistosoma mansoni amine GPCR 0.0475 0.0741 0.0741
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0304 0.045 0.1022
Brugia malayi RNA binding protein 0.0058 0.0028 0.0052
Brugia malayi cation channel family protein 0.0085 0.0074 0.0138
Brugia malayi Pepsin A precursor 0.0045 0.0007 0.0012
Echinococcus multilocularis cyclin dependent kinase 5 0.0045 0.0006 0.0009
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0517 0.0813 0.1269
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni neurotransmitter gated ion channel 0.014 0.0169 0.0169
Loa Loa (eye worm) serotonin transporter b 0.009 0.0083 0.0189
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0085 0.0074 0.0074
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0304 0.045 0.0836
Toxoplasma gondii aspartyl protease ASP1 0.0192 0.0257 0.5289
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Loa Loa (eye worm) voltage-gated calcium channel 0.0085 0.0074 0.0168
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0085 0.0074 0.0138
Echinococcus multilocularis cyclin B 0.0091 0.0085 0.0133
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus granulosus G protein coupled receptor 139 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni voltage-gated potassium channel 0.0175 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0304 0.045 0.1022
Loa Loa (eye worm) voltage-dependent calcium channel 0.0085 0.0074 0.0168
Echinococcus multilocularis sodium leak channel non selective protein 0.0085 0.0074 0.0116
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0085 0.0074 0.1416
Trichomonas vaginalis cyclin B, putative 0.0048 0.0011 0.0112
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0475 0.0741 0.1157
Brugia malayi RNA recognition motif domain containing protein 0.0058 0.0028 0.0052
Trypanosoma cruzi cyclin, putative 0.0091 0.0085 0.1756
Trypanosoma cruzi btb/poz domain containing protein, putative 0.009 0.0083 0.1704
Trypanosoma cruzi btb/poz domain containing protein, putative 0.009 0.0083 0.1704
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.014 0.0169 0.0264
Loa Loa (eye worm) TYRA-2 protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0085 0.0074 0.0074
Onchocerca volvulus 0.0475 0.0741 0.9118
Schistosoma mansoni heat shock protein 0.0134 0.0159 0.0159
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0085 0.0074 0.1523
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni opsin-like receptor 0.0475 0.0741 0.0741
Onchocerca volvulus 0.0304 0.045 0.5533
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0084 0.0072 0.0163
Plasmodium falciparum membrane associated erythrocyte binding-like protein 0.0065 0.0041 0.0837
Brugia malayi glutathione reductase 0.0047 0.0009 0.0016
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0085 0.0074 0.0138
Trichomonas vaginalis cyclins, putative 0.0048 0.0011 0.0112
Brugia malayi K+ channel tetramerisation domain containing protein 0.009 0.0083 0.0154
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.0074 0.0116
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0108 0.0114 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Entamoeba histolytica cyclin, putative 0.0048 0.0011 0.0112
Echinococcus granulosus serotonin transporter 0.009 0.0083 0.013
Schistosoma mansoni voltage-gated potassium channel 0.0175 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Echinococcus multilocularis G protein coupled receptor 139 0.3786 0.6406 1
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0592 0.0941 0.1469
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0304 0.045 0.045
Brugia malayi Transient-receptor-potential like protein 0.0085 0.0074 0.0138
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0058 0.0028 0.0064
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus multilocularis epidermal growth factor receptor 0.0163 0.0209 0.0326
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0304 0.045 0.0836
Toxoplasma gondii thioredoxin reductase 0.0047 0.0009 0.0182
Loa Loa (eye worm) hypothetical protein 0.0517 0.0813 0.1847
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Echinococcus multilocularis heat shock protein 90 0.0114 0.0125 0.0195
Brugia malayi hypothetical protein 0.014 0.0169 0.0315
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0084 0.0072 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Trypanosoma brucei heat shock protein 90, putative 0.0134 0.0159 0.3173
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Echinococcus granulosus 7tm_1 domain containing protein 0.0475 0.0741 0.1157
Loa Loa (eye worm) GABA receptor subunit 0.0164 0.021 0.0476
Loa Loa (eye worm) G-protein coupled receptor 0.0475 0.0741 0.1684
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0085 0.0074 0.0074
Trichomonas vaginalis heat shock protein, putative 0.0114 0.0125 0.2469
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.187 0.3128 0.7105
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis glycine receptor subunit beta 0.0304 0.045 0.0702
Toxoplasma gondii transporter, cation channel family protein 0.0085 0.0074 0.1523
Loa Loa (eye worm) hypothetical protein 0.0307 0.0454 0.103
Schistosoma mansoni tyrosine kinase 0.0163 0.0209 0.0209
Toxoplasma gondii K+ channel tetramerisation domain-containing protein 0.009 0.0083 0.1704
Echinococcus multilocularis BTB:POZ domain containing protein KCTD16 0.009 0.0083 0.0129
Loa Loa (eye worm) hypothetical protein 0.009 0.0083 0.0188
Entamoeba histolytica protein kinase, putative 0.0326 0.0487 1
Onchocerca volvulus 0.0073 0.0055 0.0671
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.0074 0.0074
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0057 0.0027 0.0547
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0475 0.0741 0.1377
Echinococcus granulosus cyclins 0.0048 0.0011 0.0018
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.0074 0.0116
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Brugia malayi Tachykinin-like peptides receptor 99D 0.0475 0.0741 0.1377
Loa Loa (eye worm) melatonin receptor type 1A 0.0475 0.0741 0.1684
Echinococcus multilocularis voltage gated potassium channel 0.0175 0.0228 0.0356
Loa Loa (eye worm) neuropeptide F receptor 0.0475 0.0741 0.1684
Loa Loa (eye worm) ACC-1 protein 0.0304 0.045 0.1022
Trichomonas vaginalis cyclin B, putative 0.0091 0.0085 0.1652
Onchocerca volvulus 0.0475 0.0741 0.9118
Brugia malayi Serotonin receptor 0.0475 0.0741 0.1377
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0175 0.0228 0.0356
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Plasmodium vivax protein kinase Crk2 0.0045 0.0006 0.0125
Echinococcus granulosus voltage gated hydrogen channel 1 0.0085 0.0074 0.0116
Echinococcus multilocularis cyclin b3 0.0048 0.0011 0.0018
Echinococcus granulosus nmda type glutamate receptor 0.0113 0.0123 0.0192
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0304 0.045 0.045
Plasmodium falciparum plasmepsin VII 0.0045 0.0007 0.0137
Schistosoma mansoni amine GPCR 0.0475 0.0741 0.0741
Schistosoma mansoni voltage-gated cation channel 0.0085 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.03 0.0442 0.0442
Echinococcus granulosus cyclins 0.0048 0.0011 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0006 0.0006
Treponema pallidum sodium- and chloride- dependent transporter 0.009 0.0083 0.2603
Toxoplasma gondii aspartyl protease 0.0045 0.0007 0.0137
Trypanosoma brucei Heat shock protein 83, putative 0.0134 0.0159 0.3173
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0475 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni nAChR subunit 0.014 0.0169 0.0169
Echinococcus granulosus transient receptor potential gamma protein 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0475 0.0741 0.1157
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0592 0.0941 0.1469
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.009 0.0083 0.0188
Trichomonas vaginalis cyclins, putative 0.0055 0.0023 0.0351
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0085 0.0074 0.0074
Loa Loa (eye worm) endoplasmin 0.0134 0.0159 0.036
Brugia malayi latrophilin 2 splice variant baaae 0.1278 0.2116 0.3931
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Entamoeba histolytica protein kinase , putative 0.0326 0.0487 1
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0045 0.0006 0.0125
Brugia malayi Dopamine receptor protein 2 0.0475 0.0741 0.1377
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.0074 0.0116
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Plasmodium vivax aspartyl protease, putative 0.0045 0.0007 0.0137
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0475 0.0741 0.1157
Plasmodium vivax kelch protein K13, putative 0.009 0.0083 0.1704
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0006 0.0006
Brugia malayi mbt repeat family protein 0.0073 0.0055 0.0101
Plasmodium falciparum plasmepsin III 0.0045 0.0007 0.0137
Brugia malayi Calcitonin receptor-like protein seb-1 0.2615 0.4402 0.8181
Echinococcus multilocularis epidermal growth factor receptor 0.0304 0.0449 0.0702
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Brugia malayi ion channel NompC 0.0085 0.0074 0.0138
Brugia malayi Melatonin receptor type 1A 0.0475 0.0741 0.1377
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0304 0.045 0.1022
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.0074 0.0116
Echinococcus granulosus geminin 0.03 0.0442 0.069
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0175 0.0228 0.0424
Schistosoma mansoni opsin-like receptor 0.0475 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) norepinephrine transporter 0.009 0.0083 0.0189
Brugia malayi Endoplasmin precursor 0.0134 0.0159 0.0295
Echinococcus multilocularis microtubule associated protein 2 0.1127 0.1857 0.2899
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0192 0.0257 0.523
Echinococcus multilocularis glycine receptor subunit beta 0.0304 0.045 0.0702
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.009 0.0083 0.0188
Trypanosoma cruzi potassium voltage-gated channel, putative 0.009 0.0083 0.1704
Brugia malayi serine/threonine kinase 12 0.0326 0.0487 0.0904
Schistosoma mansoni neuropeptide F-like receptor 0.0475 0.0741 0.0741
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus granulosus alpha 1A adrenergic receptor 0.0475 0.0741 0.1157
Trichomonas vaginalis cyclins, putative 0.0091 0.0085 0.1652
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0475 0.0741 0.1157
Trichomonas vaginalis cyclins, putative 0.0091 0.0085 0.1652
Schistosoma mansoni biogenic amine receptor 0.0475 0.0741 0.0741
Plasmodium falciparum plasmepsin IX 0.0045 0.0007 0.0137
Echinococcus granulosus neuropeptide FF receptor 2 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Echinococcus multilocularis dro:myosuppressin receptor 0.0475 0.0741 0.1157
Echinococcus granulosus glycine receptor subunit beta 0.0304 0.045 0.0702
Brugia malayi aspartic protease BmAsp-1, identical 0.0045 0.0007 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0304 0.045 0.0836
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Schistosoma mansoni alpha-1 adrenergic receptor 0.0475 0.0741 0.0741
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0475 0.0741 0.1157
Brugia malayi larval opioid receptor 0.0475 0.0741 0.1377
Brugia malayi neuropeptide F receptor 0.0475 0.0741 0.1377
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.0074 0.0116
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0085 0.0074 0.0138
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0085 0.0074 0.0116
Onchocerca volvulus 0.009 0.0083 0.102
Onchocerca volvulus 0.0164 0.021 0.2578
Schistosoma mansoni calcium-activated potassium channel 0.0085 0.0074 0.0074
Brugia malayi Serotonin receptor 0.0475 0.0741 0.1377
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Brugia malayi serine/threonine-protein kinase 6 0.0326 0.0487 0.0904
Echinococcus granulosus neuropeptide receptor 0.3786 0.6406 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0175 0.0228 0.0424
Trypanosoma cruzi btb/poz domain containing protein, putative 0.009 0.0083 0.1704
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0073 0.0055 0.0671
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0085 0.0074 0.0116
Echinococcus granulosus glycine receptor subunit beta 0.0304 0.045 0.0702
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0164 0.021 0.021
Leishmania major hypothetical protein, conserved 0.009 0.0083 0.1704
Plasmodium vivax aspartyl proteinase, putative 0.0045 0.0007 0.0137
Brugia malayi K+ channel tetramerisation domain containing protein 0.009 0.0083 0.0154
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.1977 0.3311 0.5168
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0175 0.0228 0.0356
Mycobacterium ulcerans heat shock protein 90 0.0114 0.0125 0.0147
Schistosoma mansoni endoplasmin 0.0134 0.0159 0.0159
Plasmodium vivax apical membrane antigen 1 0.0276 0.0402 0.8257
Trypanosoma cruzi cyclin, putative 0.0091 0.0085 0.1756
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0028 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.009 0.0083 0.1704
Plasmodium vivax endoplasmin, putative 0.0134 0.0159 0.3258
Schistosoma mansoni sex comb on midleg homolog 0.0073 0.0055 0.0055
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0045 0.0006 0.0009
Leishmania major hypothetical protein, conserved 0.009 0.0083 0.1704
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0114 0.2236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0108 0.0114 0.2333
Echinococcus granulosus endoplasmin 0.0114 0.0125 0.0195
Schistosoma mansoni neuropeptide receptor 0.0475 0.0741 0.0741
Onchocerca volvulus 0.0045 0.0007 0.0082
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0057 0.0027 0.0027
Echinococcus multilocularis hyperpolarization activated cyclic 0.0085 0.0074 0.0116
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0033 0.0033
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0517 0.0813 0.1269
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Toxoplasma gondii kelch repeat and K+ channel tetramerisation domain containing protein 0.009 0.0083 0.1704
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0011 0.0018
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.0074 0.0116
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Brugia malayi Cation transporter family protein 0.0304 0.045 0.0836
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Brugia malayi cell division control protein 2 homolog 0.0045 0.0006 0.0011
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0006 0.0125
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0085 0.0074 0.0116
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0111 0.0264
Onchocerca volvulus 0.0304 0.045 0.5533
Echinococcus multilocularis insulin receptor 0.0097 0.0095 0.0149
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0009 0.0014
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0085 0.0074 0.0138
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0257 0.0369 0.0685
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0164 0.021 0.0389
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0108 0.0114 0.2236
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0114 0.0125 0.0036
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Schistosoma mansoni edp1-related 0.009 0.0083 0.0083
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.009 0.0083 0.0188
Loa Loa (eye worm) hypothetical protein 0.009 0.0083 0.0189
Onchocerca volvulus 0.009 0.0083 0.102
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.014 0.0169 0.0384
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.014 0.0169 0.0315
Entamoeba histolytica cyclin, putative 0.0091 0.0085 0.1652
Echinococcus granulosus epidermal growth factor receptor 0.0304 0.0449 0.0702
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.0074 0.0074
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0085 0.0074 0.0138
Entamoeba histolytica cyclin family protein 0.0048 0.0011 0.0112
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0048 0.0011 0.0018
Echinococcus multilocularis potassium voltage gated channel protein 0.2067 0.3465 0.5409
Giardia lamblia Grp94/Hsp90 0.0114 0.0125 0.2469
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0083 0.0083
Brugia malayi TAR-binding protein 0.0058 0.0028 0.0052
Brugia malayi AKH receptor 0.0475 0.0741 0.1377
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus granulosus two pore calcium channel protein 1 0.0085 0.0074 0.0116
Echinococcus multilocularis sodium channel protein 0.0189 0.0252 0.0393
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0304 0.045 0.0702
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0164 0.021 0.021
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0257 0.0369 0.0837
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0304 0.045 0.0836
Plasmodium falciparum protein kinase 5 0.0045 0.0006 0.0125
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0057 0.0027 0.0428
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0304 0.045 0.0702
Schistosoma mansoni voltage-gated potassium channel 0.2067 0.3465 0.3465
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0085 0.0074 0.1416
Loa Loa (eye worm) AUR protein kinase 0.0326 0.0487 0.1106
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Brugia malayi hypothetical protein 0.0045 0.0007 0.0012
Onchocerca volvulus 0.009 0.0083 0.102
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0592 0.0941 0.1469
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0475 0.0741 0.1377
Echinococcus granulosus heat shock protein 90 0.0134 0.0159 0.0248
Trichomonas vaginalis cyclin D, putative 0.0048 0.0011 0.0112
Loa Loa (eye worm) hypothetical protein 0.0414 0.0637 0.1446
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.009 0.0083 0.0154
Echinococcus granulosus potassium voltage gated channel protein 0.0175 0.0228 0.0356
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Schistosoma mansoni ryanodine receptor related 0.0085 0.0074 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Loa Loa (eye worm) hypothetical protein 0.0045 0.0007 0.0015
Brugia malayi Cation transporter family protein 0.0447 0.0694 0.1289
Loa Loa (eye worm) hypothetical protein 0.0043 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0592 0.0941 0.0941
Trichomonas vaginalis AGC family protein kinase 0.0326 0.0487 1
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0304 0.045 0.0836
Giardia lamblia Hypothetical protein 0.0108 0.0114 0.2236
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Echinococcus multilocularis aurora kinase A 0.0326 0.0487 0.076
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0192 0.0257 0.5289
Brugia malayi transcriptional regulator, Sir2 family protein 0.0108 0.0114 0.0211
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.0074 0.0116
Echinococcus multilocularis histone acetyltransferase MYST2 0.0084 0.0072 0.0112
Brugia malayi G protein-coupled receptor 0.0475 0.0741 0.1377
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0175 0.0228 0.0356
Schistosoma mansoni hypothetical protein 0.0204 0.0279 0.0279
Trypanosoma cruzi btb/poz domain containing protein, putative 0.009 0.0083 0.1704
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0304 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0085 0.0074 0.0116
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.017 0.0219 0.0343
Plasmodium falciparum thioredoxin reductase 0.0047 0.0009 0.0182
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0475 0.0741 0.0741
Echinococcus granulosus g-protein coupled receptor 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni endoplasmin 0.0134 0.0159 0.0159
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0085 0.0074 0.0116
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0164 0.021 0.0477
Echinococcus granulosus neuropeptide s receptor 0.2127 0.3568 0.557
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.0074 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0326 0.0487 1
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.014 0.0169 0.0264
Echinococcus multilocularis transient receptor potential gamma protein 0.0085 0.0074 0.0116
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0475 0.0741 0.1684
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0085 0.0074 0.0116
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Echinococcus granulosus voltage dependent calcium channel 0.0085 0.0074 0.0116
Echinococcus granulosus hyperpolarization activated cyclic 0.0085 0.0074 0.0116
Brugia malayi hypothetical protein 0.014 0.0169 0.0315
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.2067 0.3465 0.6438
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.0074 0.1416
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0073 0.0055 0.0055
Onchocerca volvulus Huntingtin homolog 0.0112 0.0121 0.1485
Trypanosoma cruzi cyclin 6, putative 0.0091 0.0085 0.1756
Brugia malayi Dopamine receptor 0.0475 0.0741 0.1377
Chlamydia trachomatis glutamine binding protein 0.0082 0.0068 0.5
Echinococcus granulosus heat shock protein 90 0.0114 0.0125 0.0195
Trypanosoma cruzi aurora B kinase, putative 0.0326 0.0487 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0164 0.021 0.0389
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.014 0.0169 0.0315
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0304 0.045 0.0836
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0475 0.0741 0.1157
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0085 0.0074 0.0116
Echinococcus multilocularis somatostatin receptor 0.0475 0.0741 0.1157
Echinococcus multilocularis calcium activated potassium channel 0.0088 0.008 0.0125
Loa Loa (eye worm) hypothetical protein 0.0192 0.0257 0.0585
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0475 0.0741 0.1157
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0111 0.0264
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0192 0.0257 0.0257
Echinococcus granulosus allatostatin A receptor 0.0475 0.0741 0.1157
Schistosoma mansoni two-pore calcium channel 0.0085 0.0074 0.0074
Trypanosoma cruzi heat shock protein 90, putative 0.0094 0.009 0.1859
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0326 0.0487 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Schistosoma mansoni voltage-gated potassium channel 0.0175 0.0228 0.0228
Trypanosoma brucei potassium voltage-gated channel, putative 0.009 0.0083 0.1599
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0475 0.0741 0.1157
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0304 0.045 0.0836
Echinococcus granulosus cyclin dependent kinase 5 0.0045 0.0006 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0592 0.0941 0.1749
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Echinococcus multilocularis potassium voltage gated channel protein 0.0175 0.0228 0.0356
Trypanosoma cruzi Heat shock protein 83, putative 0.0134 0.0159 0.3258
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0045 0.0006 0.0125
Echinococcus granulosus polycomb protein SCMH1 0.0073 0.0055 0.0085
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0304 0.045 0.0702
Echinococcus granulosus microtubule associated protein 2 0.1127 0.1857 0.2899
Plasmodium vivax aspartyl protease, putative 0.0045 0.0007 0.0137
Loa Loa (eye worm) hypothetical protein 0.0112 0.0121 0.0274
Plasmodium falciparum plasmepsin IV 0.0192 0.0257 0.5289
Echinococcus granulosus short transient receptor potential channel 6 0.0085 0.0074 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0111 0.0264
Trypanosoma brucei mitotic cyclin 6 0.0091 0.0085 0.1652
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0304 0.045 0.0836
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0517 0.0813 0.1269
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0108 0.0114 0.0177
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.014 0.0169 0.0264
Schistosoma mansoni voltage-gated ion channel 0.0085 0.0074 0.0074
Schistosoma mansoni 60S ribosomal protein L21 0.0085 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Giardia lamblia Heat shock protein HSP 90-alpha 0.0114 0.0125 0.2469
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0326 0.0487 0.076
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0011 0.0025
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Onchocerca volvulus Putative nachr subunit 0.0517 0.0813 1
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.2313 0.3887 1
Onchocerca volvulus Huntingtin homolog 0.0112 0.0121 0.1485
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0011 0.0018
Echinococcus multilocularis glutamate receptor 2 0.0048 0.0011 0.0018
Brugia malayi Cyclin, N-terminal domain containing protein 0.0091 0.0085 0.0159
Echinococcus multilocularis allatostatin A receptor 0.0475 0.0741 0.1157
Echinococcus granulosus aurora kinase A 0.0326 0.0487 0.076
Echinococcus multilocularis two pore calcium channel protein 2 0.0085 0.0074 0.0116
Schistosoma mansoni voltage-gated potassium channel 0.0175 0.0228 0.0228
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0192 0.0257 0.0585
Entamoeba histolytica hypothetical protein 0.0164 0.021 0.4234
Echinococcus granulosus glycine receptor subunit alpha 1 0.0304 0.045 0.0702
Loa Loa (eye worm) hypothetical protein 0.2067 0.3465 0.787
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0233 0.472
Echinococcus granulosus orexin receptor type 2 0.0475 0.0741 0.1157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.014 0.0169 0.0315
Loa Loa (eye worm) prolyl oligopeptidase 0.017 0.0219 0.0498
Schistosoma mansoni transient receptor potential channel 0.0085 0.0074 0.0074
Echinococcus granulosus neuropeptides capa receptor 0.0475 0.0741 0.1157
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.009 0.0083 0.1704
Entamoeba histolytica heat shock protein 90, putative 0.0134 0.0159 0.3173
Treponema pallidum heat shock protein 90 0.0114 0.0125 1
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Echinococcus multilocularis neuropeptide Y receptor 0.0475 0.0741 0.1157
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.009 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0475 0.0741 0.0741
Onchocerca volvulus 0.0143 0.0174 0.2146
Trichomonas vaginalis cyclin B3, putative 0.0048 0.0011 0.0112
Leishmania major cyclin 0.0091 0.0085 0.1756
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0108 0.0114 0.2236
Echinococcus multilocularis voltage gated potassium channel 0.0085 0.0074 0.0116
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0114 0.0125 0.5
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Echinococcus granulosus potassium voltage gated channel subfamily A 0.2067 0.3465 0.5409
Echinococcus granulosus glycine receptor subunit alpha 1 0.0304 0.045 0.0702
Brugia malayi K+ channel tetramerisation domain containing protein 0.009 0.0083 0.0154
Schistosoma mansoni cyclin B3 0.0048 0.0011 0.0011
Echinococcus granulosus potassium voltage gated channel protein 0.2067 0.3465 0.5409
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0369 0.7542
Schistosoma mansoni vesicular amine transporter 0.0175 0.0228 0.0228
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0085 0.0074 0.0138
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0045 0.0006 0.0125
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0175 0.0228 0.0356
Loa Loa (eye worm) hypothetical protein 0.0447 0.0694 0.1576
Loa Loa (eye worm) calcium channel 0.0085 0.0074 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0369 0.7542
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0085 0.0074 0.1523
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0108 0.0114 0.2333
Brugia malayi ORL1-like opioid receptor 0.0475 0.0741 0.1377
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0293 0.043 0.0672
Onchocerca volvulus 0.009 0.0083 0.102
Trypanosoma cruzi CYC2-like cyclin, putative 0.0091 0.0085 0.1756
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0159 0.3173
Schistosoma mansoni nAChR subunit 0.014 0.0169 0.0169
Echinococcus multilocularis potassium voltage gated channel protein 0.0085 0.0074 0.0116
Giardia lamblia Aurora kinase 0.0326 0.0487 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0085 0.0194
Schistosoma mansoni microtubule-associated protein tau 0.1127 0.1857 0.1857
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0085 0.0074 0.0116
Schistosoma mansoni hypothetical protein 0.0475 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni biogenic amine (5HT) receptor 0.0475 0.0741 0.0741
Brugia malayi follicle stimulating hormone receptor 0.0697 0.1122 0.2084
Echinococcus multilocularis g-protein coupled receptor 0.0475 0.0741 0.1157
Echinococcus multilocularis geminin 0.03 0.0442 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0369 0.7542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Echinococcus granulosus neuropeptides capa receptor 0.0475 0.0741 0.1157
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0475 0.0741 0.1377
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0304 0.045 0.0836
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.0074 0.0116
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0009 0.0182
Toxoplasma gondii apical membrane antigen AMA1 0.0065 0.0041 0.0837
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0304 0.045 0.0702
Brugia malayi solute carrier family 40, member 1 0.0414 0.0637 0.1183
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Trichomonas vaginalis cyclins, putative 0.0091 0.0085 0.1652
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Brugia malayi Cyclin, N-terminal domain containing protein 0.0048 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0011 0.0018
Echinococcus granulosus insulin receptor 0.0097 0.0095 0.0149
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0304 0.045 0.0702
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Plasmodium vivax plasmepsin V, putative 0.0045 0.0007 0.0137
Echinococcus granulosus hyperpolarization activated cyclic 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Leishmania major potassium voltage-gated channel, putative 0.009 0.0083 0.1704
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Giardia lamblia G2/mitotic-specific cyclin B 0.0091 0.0085 0.1652
Echinococcus multilocularis polycomb protein SCMH1 0.0073 0.0055 0.0085
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0475 0.0741 0.1157
Echinococcus granulosus tar DNA binding protein 0.0058 0.0028 0.0044
Echinococcus multilocularis nAChR subunit 0.0304 0.045 0.0702
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.0074 0.0116
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0369 0.7542
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0475 0.0741 0.1157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0304 0.045 0.0836
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Brugia malayi hypothetical protein 0.014 0.0169 0.0315
Brugia malayi mKIAA0176 protein 0.009 0.0083 0.0154
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0393 0.0601 0.1365
Toxoplasma gondii heat shock protein HSP90 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.009 0.0083 0.0188
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.009 0.0083 0.0188
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0189 0.0252 0.5172
Echinococcus granulosus nAChR subunit 0.0164 0.021 0.0327
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0517 0.0813 0.1269
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0304 0.045 0.0702
Loa Loa (eye worm) voltage-gated potassium channel 0.0085 0.0074 0.0168
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.0074 0.0074
Trichomonas vaginalis heat shock protein, putative 0.0114 0.0125 0.2469
Echinococcus granulosus voltage dependent calcium channel 0.0085 0.0074 0.0116
Schistosoma mansoni glutamate receptor NMDA 0.0048 0.0011 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Giardia lamblia Heat shock protein HSP 90-alpha 0.0134 0.0159 0.3173
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0304 0.045 0.0836
Echinococcus multilocularis two pore calcium channel protein 1 0.0085 0.0074 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Echinococcus multilocularis conserved hypothetical protein 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Brugia malayi prolyl oligopeptidase family protein 0.0057 0.0027 0.005
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0006 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Trypanosoma brucei BTB/POZ domain/Regulator of chromosome condensation (RCC1) repeat, putative 0.009 0.0083 0.1599
Schistosoma mansoni histamine h1 receptor 0.0475 0.0741 0.0741
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0083 0.0083
Echinococcus granulosus 7TM GPCR rhodopsin 0.0475 0.0741 0.1157
Toxoplasma gondii aurora kinase 0.0326 0.0487 1
Brugia malayi putative neuropeptide receptor NPR1 0.0475 0.0741 0.1377
Trichomonas vaginalis AGC family protein kinase 0.0326 0.0487 1
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.009 0.0083 0.0154
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.017 0.0219 0.0219
Echinococcus multilocularis serotonin receptor 0.0475 0.0741 0.1157
Echinococcus multilocularis neuropeptide Y receptor 0.0475 0.0741 0.1157
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.187 0.3128 0.5812
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0175 0.0228 0.0356
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0132 0.0316
Leishmania major protein kinase, putative 0.0326 0.0487 1
Schistosoma mansoni hypothetical protein 0.0592 0.0941 0.0941
Loa Loa (eye worm) cyclin domain-containing protein 0.0048 0.0011 0.0026
Schistosoma mansoni hypothetical protein 0.0085 0.0074 0.0074
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0268 0.0388 0.0605
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0011 0.0018
Echinococcus multilocularis heat shock protein 0.0134 0.0159 0.0248
Echinococcus granulosus neuropeptide receptor A26 0.2127 0.3568 0.557
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.0074 0.0116
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0006 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0028 0.0028
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Schistosoma mansoni sex comb on midleg homolog 0.0073 0.0055 0.0055
Onchocerca volvulus 0.0091 0.0085 0.1051
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Schistosoma mansoni tyrosine kinase 0.0162 0.0206 0.0206
Echinococcus multilocularis endoplasmin 0.0114 0.0125 0.0195
Echinococcus granulosus cyclin dependent kinase 1 0.0045 0.0006 0.0009
Schistosoma mansoni amine GPCR 0.0475 0.0741 0.0741
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0045 0.0007 0.0015
Toxoplasma gondii hypothetical protein 0.0085 0.0074 0.1523
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Leishmania major hypothetical protein, conserved 0.0085 0.0074 0.1523
Echinococcus granulosus fmrfamide receptor 0.0475 0.0741 0.1157
Onchocerca volvulus 0.014 0.0169 0.2082
Echinococcus multilocularis SAM and MBT domain containing protein 0.0073 0.0055 0.0085
Echinococcus multilocularis chromatin regulatory protein sir2 0.0108 0.0114 0.0177
Echinococcus granulosus chromatin regulatory protein sir2 0.0108 0.0114 0.0177
Schistosoma mansoni hypothetical protein 0.0408 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Loa Loa (eye worm) acetylcholine receptor protein 0.014 0.0169 0.0384
Loa Loa (eye worm) hypothetical protein 0.009 0.0083 0.0188
Schistosoma mansoni biogenic amine receptor 0.0475 0.0741 0.0741
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0085 0.0074 0.1523
Echinococcus multilocularis GPCR, family 2 0.0592 0.0941 0.1469
Schistosoma mansoni myosin xvIII 0.0475 0.0741 0.0741
Echinococcus granulosus ryanodine receptor 44f 0.0085 0.0074 0.0116
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0326 0.0487 1
Echinococcus multilocularis potassium large conductance calcium activated 0.0085 0.0074 0.0116
Brugia malayi cation channel family protein 0.0085 0.0074 0.0138
Loa Loa (eye worm) hypothetical protein 0.0447 0.0694 0.1576
Loa Loa (eye worm) transcriptional regulator 0.0108 0.0114 0.0258
Plasmodium falciparum endoplasmin, putative 0.006 0.0031 0.0637
Schistosoma mansoni neuropeptide F-like receptor 0.0475 0.0741 0.0741
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.0044 0.0004 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0475 0.0741 0.0741
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0304 0.045 0.0836
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni nAChR subunit 0.0304 0.045 0.045
Onchocerca volvulus 0.0414 0.0637 0.783
Entamoeba histolytica heat shock protein 90, putative 0.0134 0.0159 0.3173
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0085 0.0074 0.0074
Brugia malayi hypothetical protein 0.0045 0.0007 0.0012
Schistosoma mansoni voltage-dependent calcium channel 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0517 0.0813 0.1269
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Entamoeba histolytica cyclin family protein 0.0048 0.0011 0.0112
Schistosoma mansoni amine GPCR 0.0475 0.0741 0.0741
Plasmodium vivax glutathione reductase, putative 0.0047 0.0009 0.0182
Echinococcus multilocularis transfer RNA-Gly 0.0175 0.0228 0.0356
Echinococcus granulosus tachykinin peptides receptor 99D 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0114 0.0114
Mycobacterium tuberculosis Probable reductase 0.0106 0.0111 0.0264
Trichomonas vaginalis cyclin A, putative 0.0091 0.0085 0.1652
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus granulosus epidermal growth factor receptor 0.0163 0.0209 0.0326
Loa Loa (eye worm) TK/ROR protein kinase 0.0043 0.0003 0.0007
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.014 0.0169 0.0264
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0475 0.0741 0.1157
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0011 0.0112
Brugia malayi hypothetical protein 0.0143 0.0174 0.0324
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0517 0.0813 0.1269
Brugia malayi excitatory GABA receptor EXP-1A 0.0304 0.045 0.0836
Schistosoma mansoni cyclins 0.0048 0.0011 0.0011
Schistosoma mansoni myelin transcription factor 1 myt1 0.0084 0.0072 0.0072
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0475 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus granulosus two pore calcium channel protein 2 0.0085 0.0074 0.0116
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.077 0.1246 0.1945
Echinococcus multilocularis cyclins 0.0048 0.0011 0.0018
Onchocerca volvulus 0.014 0.0169 0.2082
Leishmania major hypothetical protein, unknown function 0.0085 0.0074 0.1523
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0475 0.0741 0.1157
Echinococcus granulosus biogenic amine 5HT receptor 0.0475 0.0741 0.1157
Plasmodium falciparum plasmepsin II 0.0192 0.0257 0.5289
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0175 0.0228 0.0518
Trypanosoma brucei aurora B kinase 0.0326 0.0487 1
Echinococcus multilocularis cyclin dependent kinase 0.0045 0.0006 0.0009
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0057 0.0027 0.0547
Brugia malayi sulfakinin receptor protein 0.0475 0.0741 0.1377
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0045 0.0006 0.0014
Schistosoma mansoni tyrosine kinase 0.0304 0.0449 0.0449
Trypanosoma cruzi heat shock protein 85, putative 0.0114 0.0125 0.2563
Echinococcus granulosus g protein coupled receptor 0.0475 0.0741 0.1157
Onchocerca volvulus 0.0045 0.0007 0.0082
Schistosoma mansoni transient receptor potential channel 0.0085 0.0074 0.0074
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Loa Loa (eye worm) glutathione reductase 0.0047 0.0009 0.002
Echinococcus multilocularis hyperpolarization activated cyclic 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0447 0.0694 0.0694
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0475 0.0741 0.1684
Trypanosoma cruzi btb/poz domain containing protein, putative 0.009 0.0083 0.1704
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0011 0.0018
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.0074 0.0116
Brugia malayi olfactory channel protein osm-9 0.0085 0.0074 0.0138
Echinococcus multilocularis g protein coupled receptor 0.0475 0.0741 0.1157
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Trichomonas vaginalis cyclin B, putative 0.0091 0.0085 0.1652
Echinococcus granulosus BTB:POZ domain containing protein 0.009 0.0083 0.0129
Echinococcus granulosus GPCR family 2 0.0592 0.0941 0.1469
Brugia malayi G-protein coupled receptor 0.0475 0.0741 0.1377
Echinococcus multilocularis g protein coupled receptor 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Echinococcus multilocularis neuropeptides capa receptor 0.0475 0.0741 0.1157
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.017 0.0219 0.2699
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Trichomonas vaginalis endoplasmin, putative 0.006 0.0031 0.0519
Brugia malayi serine/threonine protein kinase 6 0.0326 0.0487 0.0904
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0304 0.045 0.0836
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0085 0.0074 0.0116
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.0627 0.0979
Plasmodium falciparum plasmepsin X 0.0045 0.0007 0.0137
Plasmodium falciparum glutathione reductase 0.0047 0.0009 0.0182
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0009 0.002
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0085 0.0074 0.0168
Plasmodium falciparum plasmepsin I 0.0192 0.0257 0.5289
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Echinococcus multilocularis tar DNA binding protein 0.0058 0.0028 0.0044
Brugia malayi Thioredoxin reductase 0.0047 0.0009 0.0016
Schistosoma mansoni biogenic amine receptor 0.0475 0.0741 0.0741
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Echinococcus multilocularis nmda type glutamate receptor 0.0113 0.0123 0.0192
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0326 0.0487 1
Brugia malayi hypothetical protein 0.0112 0.0121 0.0224
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus granulosus glycine receptor subunit alpha 1 0.0304 0.045 0.0702
Loa Loa (eye worm) hypothetical protein 0.009 0.0083 0.0189
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0164 0.021 0.0389
Echinococcus multilocularis nAChR subunit 0.0164 0.021 0.0327
Echinococcus granulosus neuropeptide Y receptor 0.0475 0.0741 0.1157
Brugia malayi Cyclic-nucleotide gated cation channel 0.0085 0.0074 0.0138
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0159 0.3258
Brugia malayi hypothetical protein 0.014 0.0169 0.0315
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis neuropeptide receptor 0.0475 0.0741 0.1157
Schistosoma mansoni cathepsin D (A01 family) 0.0566 0.0897 0.0897
Plasmodium vivax merozoite adhesive erythrocytic binding protein 0.0065 0.0041 0.0837
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Echinococcus multilocularis g protein coupled receptor 0.0475 0.0741 0.1157
Echinococcus granulosus cyclin dependent kinase 0.0045 0.0006 0.0009
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0045 0.0007 0.0137
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.0074 0.0116
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0475 0.0741 0.1157
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0304 0.045 0.0836
Trypanosoma cruzi heat shock protein 90, putative 0.0134 0.0159 0.3258
Toxoplasma gondii heat shock protein 90, putative 0.0134 0.0159 0.3258
Schistosoma mansoni biogenic amine (5HT) receptor 0.0475 0.0741 0.0741
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0057 0.0027 0.0428
Trypanosoma brucei RNA helicase, putative 0.0204 0.0279 0.5675
Echinococcus multilocularis neuropeptide receptor A26 0.2127 0.3568 0.557
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0085 0.0074 0.0168
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.0074 0.0074
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0326 0.0487 1
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0085 0.0074 0.0138
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0475 0.0741 0.0741
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0159 0.3258
Schistosoma mansoni amine GPCR 0.0475 0.0741 0.0741
Plasmodium vivax heat shock protein 86, putative 0.0134 0.0159 0.3258
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0475 0.0741 0.9118
Loa Loa (eye worm) TK/EGFR protein kinase 0.0304 0.0449 0.1021
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0163 0.0209 0.0326
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0475 0.0741 0.1684
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni serine-type protease inhibitor 0.5887 1 1
Echinococcus granulosus dnaJ subfamily B 0.0408 0.0627 0.0979
Echinococcus multilocularis fmrfamide receptor 0.0475 0.0741 0.1157
Trypanosoma brucei btb/poz domain containing protein, putative 0.009 0.0083 0.1599
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0082 0.0068 0.0154
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Schistosoma mansoni acetylcholine receptor-related 0.014 0.0169 0.0169
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0111 0.0264
Onchocerca volvulus 0.0447 0.0694 0.8534
Onchocerca volvulus 0.0475 0.0741 0.9118
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0111 0.0264
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0475 0.0741 0.0741
Loa Loa (eye worm) heat shock protein 90 0.0134 0.0159 0.036
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0697 0.1122 0.2547
Plasmodium vivax aspartyl proteinase, putative 0.0192 0.0257 0.5289
Echinococcus granulosus SAM and MBT domain containing protein 0.0073 0.0055 0.0085
Echinococcus granulosus cyclins 0.0048 0.0011 0.0018
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0006 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0233 0.472
Echinococcus granulosus sodium channel protein 0.0189 0.0252 0.0393
Schistosoma mansoni hypothetical protein 0.1278 0.2116 0.2116
Echinococcus granulosus g protein coupled receptor 0.0475 0.0741 0.1157
Echinococcus granulosus heat shock protein 0.0134 0.0159 0.0248
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0475 0.0741 0.0741
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0304 0.045 0.0702
Brugia malayi putative neuropeptide receptor 0.0475 0.0741 0.1377
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.0074 0.0116
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0085 0.0074 0.0116
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0293 0.043 0.0672
Brugia malayi G-protein coupled receptor 0.0475 0.0741 0.1377
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Leishmania major silent information regulator 2, putative 0.0108 0.0114 0.2333
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0085 0.0074 0.0138
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Schistosoma mansoni voltage-gated potassium channel 0.0175 0.0228 0.0228
Echinococcus granulosus rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Echinococcus granulosus neuropeptide Y receptor 0.0475 0.0741 0.1157
Schistosoma mansoni voltage-gated potassium channel 0.0175 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Schistosoma mansoni memapsin-2 (A01 family) 0.0045 0.0007 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0028 0.0028
Onchocerca volvulus 0.0475 0.0741 0.9118
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Echinococcus multilocularis neuropeptide s receptor 0.2127 0.3568 0.557
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0095 0.0149
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0517 0.0813 0.1511
Brugia malayi GnHR receptor homolog 0.3187 0.5382 1
Echinococcus granulosus BTB:POZ domain containing protein KCTD16 0.009 0.0083 0.0129
Brugia malayi RE15519p 0.0475 0.0741 0.1377
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0189 0.0252 0.0626
Leishmania major trypanothione reductase 0.0047 0.0009 0.0182
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0475 0.0741 0.1157
Onchocerca volvulus 0.009 0.0083 0.1022
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.2313 0.3887 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.0074 0.0116
Trypanosoma brucei potassium voltage-gated channel, putative 0.009 0.0083 0.1599
Echinococcus granulosus glutamate NMDA receptor subunit 0.0268 0.0388 0.0605
Echinococcus granulosus tm gpcr rhodopsin 0.0475 0.0741 0.1157
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0095 0.0217
Brugia malayi G protein-coupled receptor F59B2.13 0.0475 0.0741 0.1377
Echinococcus granulosus serotonin receptor 0.0475 0.0741 0.1157
Echinococcus granulosus potassium large conductance calcium activated 0.0085 0.0074 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0304 0.045 0.0702
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Brugia malayi Dopamine receptor protein 1 0.0475 0.0741 0.1377
Brugia malayi Cyclin, N-terminal domain containing protein 0.0091 0.0085 0.0159
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0304 0.045 0.0702
Echinococcus multilocularis sex peptide receptor 0.0475 0.0741 0.1157
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0475 0.0741 0.0741
Brugia malayi hypothetical protein 0.014 0.0169 0.0315
Leishmania major heat shock protein 83-1 0.0134 0.0159 0.3258
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni transient receptor potential channel 4 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.014 0.0169 0.0384
Echinococcus granulosus somatostatin receptor 0.0475 0.0741 0.1157
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0475 0.0741 0.1377
Onchocerca volvulus 0.0475 0.0741 0.9118
Brugia malayi prolyl oligopeptidase family protein 0.017 0.0219 0.0408
Schistosoma mansoni hypothetical protein 0.03 0.0442 0.0442
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0475 0.0741 0.0741
Trypanosoma brucei trypanothione reductase 0.0047 0.0009 0.0059
Trypanosoma cruzi btb/poz domain containing protein, putative 0.009 0.0083 0.1704
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0304 0.045 0.1022
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.2313 0.3887 1
Onchocerca volvulus 0.0164 0.021 0.2578
Onchocerca volvulus 0.009 0.0083 0.102
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.014 0.0169 0.0315
Echinococcus granulosus short transient receptor potential channel 6 0.0085 0.0074 0.0116
Trypanosoma brucei btb/poz domain containing protein, putative 0.009 0.0083 0.1599
Schistosoma mansoni sodium/chloride dependent transporter 0.009 0.0083 0.0083
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0048 0.0011 0.0018
Onchocerca volvulus 0.0475 0.0741 0.9118
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0132 0.0316
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0475 0.0741 0.1684
Echinococcus multilocularis orexin receptor type 2 0.0475 0.0741 0.1157
Trypanosoma brucei heat shock protein 90, putative 0.0134 0.0159 0.3173
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) ACC-1 protein 0.0304 0.045 0.1022
Trichomonas vaginalis cyclin D, putative 0.0048 0.0011 0.0112
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni hypothetical protein 0.045 0.0699 0.0699
Schistosoma mansoni tyrosine kinase 0.0163 0.0209 0.0209
Plasmodium falciparum kelch protein K13 0.009 0.0083 0.1704
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.0074 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Schistosoma mansoni tyrosine kinase 0.0097 0.0095 0.0095
Loa Loa (eye worm) AUR protein kinase 0.0326 0.0487 0.1106
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0085 0.0074 0.0116
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Onchocerca volvulus 0.0475 0.0741 0.9118
Onchocerca volvulus Glucosylceramidase homolog 0.0169 0.0217 0.2674
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.0074 0.0116
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0113 0.0123 0.0192
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0475 0.0741 0.0741
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Loa Loa (eye worm) hypothetical protein 0.009 0.0083 0.0189
Schistosoma mansoni neuropeptide receptor 0.3786 0.6406 0.6406
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.014 0.0169 0.0264
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0006 0.0125
Brugia malayi Angiotensin-converting enzyme family protein 0.0164 0.021 0.039
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0304 0.045 0.0702
Brugia malayi Protein kinase domain containing protein 0.0097 0.0095 0.0177
Brugia malayi Cation transporter family protein 0.0304 0.045 0.0836
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Brugia malayi hypothetical protein 0.0475 0.0741 0.1377
Echinococcus granulosus cyclin B3 1 0.0048 0.0011 0.0018
Echinococcus granulosus calcium activated potassium channel 0.0088 0.008 0.0125
Schistosoma mansoni acetylcholine receptor subunit beta 0.014 0.0169 0.0169
Loa Loa (eye worm) aspartyl protease 6 0.0045 0.0007 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0022 0.0449
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0192 0.0257 0.0402
Echinococcus granulosus cyclins 0.0048 0.0011 0.0018
Brugia malayi K+ channel tetramerisation domain containing protein 0.009 0.0083 0.0154
Brugia malayi hypothetical protein 0.0044 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0592 0.0941 0.0941
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Toxoplasma gondii aspartyl protease ASP3 0.0045 0.0007 0.0137
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0057 0.0027 0.0042
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0175 0.0228 0.0356
Schistosoma mansoni hypothetical protein 0.0475 0.0741 0.0741
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.0162 0.0206 0.0206
Trypanosoma cruzi potassium voltage-gated channel 0.009 0.0083 0.1704
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.0487 0.0487
Onchocerca volvulus 0.0475 0.0741 0.9118
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.0074 0.1416
Loa Loa (eye worm) RNA binding protein 0.0058 0.0028 0.0064
Brugia malayi neuropeptide F receptor 0.0475 0.0741 0.1377
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0217 0.4397
Entamoeba histolytica protein kinase domain containing protein 0.0326 0.0487 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.021 0.0476
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0168
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni neurotransmitter gated ion channel 0.014 0.0169 0.0169
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0132 0.0054
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0085 0.0074 0.1523
Trichomonas vaginalis cyclin B, putative 0.0091 0.0085 0.1652
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.0074 0.0116
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0095 0.0149
Echinococcus multilocularis short transient receptor potential channel 6 0.0085 0.0074 0.0116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0475 0.0741 0.0741
Plasmodium falciparum apical membrane antigen 1 0.0276 0.0402 0.8257
Loa Loa (eye worm) hypothetical protein 0.0475 0.0741 0.1684
Schistosoma mansoni voltage-gated potassium channel 0.2067 0.3465 0.3465
Onchocerca volvulus 0.0304 0.045 0.5533
Toxoplasma gondii transporter, cation channel family protein 0.0085 0.0074 0.1523
Loa Loa (eye worm) TAR-binding protein 0.0058 0.0028 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0475 0.0741 0.0741
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Echinococcus multilocularis serotonin transporter 0.009 0.0083 0.013
Echinococcus multilocularis potassium voltage gated channel protein 0.0175 0.0228 0.0356
Echinococcus multilocularis heat shock protein 90 0.0134 0.0159 0.0248
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0028 0.0028
Echinococcus granulosus g protein coupled receptor 0.0475 0.0741 0.1157
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0592 0.0941 0.1469
Loa Loa (eye worm) hypothetical protein 0.0304 0.045 0.1022
Echinococcus multilocularis ryanodine receptor 44f 0.0085 0.0074 0.0116
Echinococcus granulosus dro:myosuppressin receptor 0.0475 0.0741 0.1157
Echinococcus multilocularis 0.0094 0.009 0.0141
Schistosoma mansoni heat shock protein 0.0134 0.0159 0.0159
Onchocerca volvulus Neuropeptide F receptor homolog 0.0475 0.0741 0.9118
Schistosoma mansoni cyclin B 0.0091 0.0085 0.0085
Loa Loa (eye worm) AUR protein kinase 0.0326 0.0487 0.1106
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0304 0.045 0.1022
Trypanosoma brucei heat shock protein, putative 0.0134 0.0159 0.3173
Echinococcus multilocularis serotonin receptor 0.0475 0.0741 0.1157
Brugia malayi heat shock protein 90 0.0134 0.0159 0.0295
Brugia malayi voltage-dependent calcium channel 0.0085 0.0074 0.0138
Toxoplasma gondii hypothetical protein 0.0085 0.0074 0.1523
Loa Loa (eye worm) solute carrier family 6 member 4 0.009 0.0083 0.0189
Loa Loa (eye worm) G-protein coupled receptor 0.0475 0.0741 0.1684
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0011 0.0018
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0057 0.0027 0.0547
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0114 0.0114
Echinococcus multilocularis rhodopsin orphan GPCR 0.0475 0.0741 0.1157
Schistosoma mansoni tyrosine kinase 0.0162 0.0206 0.0206

Activities

Activity type Activity value Assay description Source Reference
MST (functional) = 13.5 day Antineoplastic activity in P-388-tumor cell infected CDF1 mice, administered intraperitoneally at a dose (80mg/kg), calculated as Median survival time (MST) ChEMBL. 2909734
MST (functional) = 13.8 day Antineoplastic activity in P-388-tumor cell infected CDF1 mice, administered intraperitoneally at a dose (10mg/kg), calculated as Median survival time (MST) ChEMBL. 2909734
MST (functional) = 15 day Antineoplastic activity in P-388-tumor cell infected CDF1 mice, administered intraperitoneally at a dose (20mg/kg), calculated as Median survival time (MST) ChEMBL. 2909734
MST (functional) = 18 day Antineoplastic activity in P-388-tumor cell infected CDF1 mice, administered intraperitoneally at a dose (40mg/kg), calculated as Median survival time (MST) ChEMBL. 2909734
T/C (functional) = 137 % Antineoplastic activity of the compound in P-388-infected CDF1 mice, administered intraperitoneally at a dose (80mg/kg), calculated as Percent treated /control (T/C). ChEMBL. 2909734
T/C (functional) = 141 % Antineoplastic activity of the compound in P-388-infected CDF1 mice, administered intraperitoneally at a dose (10mg/kg), calculated as Percent treated /control (T/C). ChEMBL. 2909734
T/C (functional) = 153 % Antineoplastic activity of the compound in P-388-infected CDF1 mice, administered intraperitoneally at a dose (20mg/kg), calculated as Percent treated /control (T/C). ChEMBL. 2909734
T/C (functional) = 183 % Antineoplastic activity of the compound in P-388-infected CDF1 mice, administered intraperitoneally at a dose (40mg/kg), calculated as Percent treated /control (T/C). ChEMBL. 2909734

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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