Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0076 | 0.0863 | 0.1228 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0283 | 0.0397 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0283 | 0.0283 |
Onchocerca volvulus | 0.0076 | 0.0863 | 0.1787 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0076 | 0.0863 | 0.1228 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0049 | 0.0448 | 0.0635 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0863 | 0.4732 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0863 | 0.2109 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0087 | 0.1025 | 0.1452 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0049 | 0.0448 | 0.0635 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0049 | 0.0448 | 0.0635 |
Echinococcus granulosus | peregrin | 0.0038 | 0.0294 | 0.0294 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0863 | 0.1228 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0177 | 0.0248 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.0481 | 0.264 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.011 | 0.1367 | 0.3341 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.011 | 0.1367 | 0.3341 |
Echinococcus granulosus | lamin | 0.0058 | 0.0586 | 0.0586 |
Loa Loa (eye worm) | glutathione reductase | 0.014 | 0.1823 | 0.2552 |
Brugia malayi | RNA binding protein | 0.0261 | 0.3635 | 0.5088 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0099 | 0.12 | 0.168 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0553 | 0.0784 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0102 | 0.1246 | 0.1246 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.0553 | 0.0553 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0333 | 0.1775 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0049 | 0.0448 | 0.2458 |
Onchocerca volvulus | 0.0286 | 0.4013 | 1 | |
Echinococcus granulosus | lamin dm0 | 0.0058 | 0.0586 | 0.0586 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0076 | 0.0863 | 0.1228 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0261 | 0.3635 | 0.5088 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0936 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.0553 | 0.0788 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.0283 | 0.0283 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.008 | 0.0916 | 0.4887 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.1072 | 0.1072 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0333 | 0.0814 |
Onchocerca volvulus | 0.0041 | 0.0336 | 0.0415 | |
Leishmania major | glycosyl hydrolase-like protein | 0.0041 | 0.0333 | 0.1825 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0761 | 0.0761 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0494 | 0.7144 | 0.7144 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0494 | 0.7144 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0076 | 0.0863 | 0.1208 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0036 | 0.0255 | 0.0356 |
Leishmania major | trypanothione reductase | 0.014 | 0.1823 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.011 | 0.1367 | 0.3341 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0333 | 0.0466 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.0481 | 0.0674 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0553 | 0.0775 |
Entamoeba histolytica | hypothetical protein | 0.0143 | 0.1875 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0311 | 0.44 | 0.6159 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0185 | 0.2022 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0087 | 0.1025 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0863 | 0.1208 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0761 | 0.1066 |
Schistosoma mansoni | lamin | 0.0058 | 0.0586 | 0.0586 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0761 | 0.0761 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.1072 | 0.1072 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0143 | 0.1875 | 0.1875 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.12 | 0.12 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.011 | 0.1367 | 0.1913 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0475 | 0.6863 | 0.6863 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0041 | 0.0333 | 0.0466 |
Schistosoma mansoni | jumonji domain containing protein | 0.0081 | 0.0932 | 0.0932 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0099 | 0.12 | 0.12 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.0682 | 0.0954 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0076 | 0.0863 | 0.1228 |
Brugia malayi | TAR-binding protein | 0.0261 | 0.3635 | 0.5088 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0488 | 0.7058 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0863 | 0.2109 |
Loa Loa (eye worm) | glutaminase | 0.0291 | 0.409 | 0.5725 |
Loa Loa (eye worm) | hypothetical protein | 0.0213 | 0.2919 | 0.4086 |
Mycobacterium ulcerans | glutaminase | 0.0291 | 0.409 | 0.5795 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0355 | 0.5054 | 0.7194 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0099 | 0.12 | 0.168 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.1498 | 0.2096 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.011 | 0.1367 | 0.7289 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0185 | 0.0262 |
Onchocerca volvulus | 0.0058 | 0.0586 | 0.1065 | |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.12 | 0.12 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0761 | 0.1861 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0295 | 0.416 | 0.5823 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1072 | 0.1072 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0049 | 0.0448 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.057 | 0.0798 |
Loa Loa (eye worm) | glutaminase 2 | 0.0291 | 0.409 | 0.5725 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0183 | 0.0257 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.032 | 0.453 | 0.5919 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.0481 | 0.0674 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0481 | 0.1177 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0166 | 0.0235 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.0481 | 0.264 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0863 | 0.1222 |
Brugia malayi | hypothetical protein | 0.0143 | 0.1875 | 0.2624 |
Brugia malayi | glutathione reductase | 0.014 | 0.1823 | 0.2552 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0931 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0049 | 0.0448 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0121 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0863 | 0.1208 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0166 | 0.0166 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0076 | 0.0863 | 0.1228 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.12 | 0.168 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.014 | 0.1823 | 0.2595 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0099 | 0.12 | 0.12 |
Echinococcus granulosus | peptidase Clp S14 family | 0.032 | 0.453 | 0.453 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0319 | 0.4518 | 0.6432 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0657 | 0.0657 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.011 | 0.1367 | 0.1367 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0684 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0863 | 0.1208 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.011 | 0.1367 | 0.3341 |
Loa Loa (eye worm) | TAR-binding protein | 0.0261 | 0.3635 | 0.5088 |
Mycobacterium ulcerans | hypothetical protein | 0.0076 | 0.0863 | 0.1222 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0261 | 0.3635 | 0.5088 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0166 | 0.0166 |
Echinococcus multilocularis | tar DNA binding protein | 0.0261 | 0.3635 | 0.3635 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0185 | 0.0259 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0295 | 0.416 | 0.416 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0049 | 0.0448 | 0.0635 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0143 | 0.1875 | 0.1875 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0076 | 0.0863 | 0.1222 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0058 | 0.0586 | 0.082 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0076 | 0.0863 | 0.1208 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0049 | 0.0448 | 0.0448 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0049 | 0.0448 | 0.0638 |
Brugia malayi | Thioredoxin reductase | 0.014 | 0.1823 | 0.2552 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0168 | 0.2248 | 0.3184 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0355 | 0.5054 | 0.7194 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0049 | 0.0448 | 0.2458 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0333 | 0.0814 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.1498 | 0.2096 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.1072 | 0.1072 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0863 | 0.4732 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0121 | 0.017 |
Mycobacterium ulcerans | beta-lactamase | 0.0076 | 0.0863 | 0.1222 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0087 | 0.1025 | 0.2506 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0863 | 0.0863 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0863 | 0.2109 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0481 | 0.264 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 0.7058 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0185 | 0.0262 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0049 | 0.0448 | 0.2458 |
Echinococcus granulosus | GPCR family 2 | 0.0099 | 0.12 | 0.12 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0333 | 0.0814 |
Brugia malayi | beta-lactamase | 0.0076 | 0.0863 | 0.1208 |
Echinococcus multilocularis | peregrin | 0.0038 | 0.0294 | 0.0294 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.12 | 0.12 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0657 | 0.0657 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0355 | 0.5054 | 0.6765 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0761 | 0.1861 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0185 | 0.0185 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0311 | 0.44 | 0.6159 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0586 | 0.082 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0087 | 0.1025 | 0.1452 |
Brugia malayi | glutaminase DH11.1 | 0.0291 | 0.409 | 0.5725 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0863 | 0.1208 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0168 | 0.2248 | 0.2235 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.011 | 0.1367 | 0.1367 |
Schistosoma mansoni | alpha glucosidase | 0.011 | 0.1367 | 0.1367 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.1498 | 0.2096 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0303 | 0.0742 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0863 | 0.1208 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.0481 | 0.264 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0657 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0185 | 0.0262 |
Loa Loa (eye worm) | beta-lactamase | 0.0076 | 0.0863 | 0.1208 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.1875 | 0.1875 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0475 | 0.6863 | 0.6863 |
Mycobacterium ulcerans | lipase LipD | 0.0076 | 0.0863 | 0.1222 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0761 | 0.0761 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0348 | 0.085 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0295 | 0.416 | 0.416 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0185 | 0.0185 |
Schistosoma mansoni | glutaminase | 0.0291 | 0.409 | 0.409 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0319 | 0.4518 | 0.5901 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.014 | 0.1823 | 0.1823 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0448 | 0.2458 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0049 | 0.0448 | 0.1096 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.011 | 0.1367 | 0.1913 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0475 | 0.6863 | 0.6863 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.0481 | 0.0481 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.0553 | 0.3035 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0333 | 0.0814 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0863 | 0.1208 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.014 | 0.1823 | 0.1823 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0133 | 0.0325 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0287 | 0.4035 | 0.4035 |
Entamoeba histolytica | hypothetical protein | 0.0143 | 0.1875 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0166 | 0.0166 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0863 | 0.2109 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0761 | 0.0761 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.0481 | 0.0682 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0863 | 0.1228 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0041 | 0.0333 | 0.0406 |
Onchocerca volvulus | 0.0076 | 0.0863 | 0.1787 | |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0049 | 0.0448 | 0.0448 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0049 | 0.0448 | 0.0635 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0099 | 0.12 | 0.12 |
Echinococcus multilocularis | lamin | 0.0058 | 0.0586 | 0.0586 |
Plasmodium vivax | thioredoxin reductase, putative | 0.014 | 0.1823 | 0.2583 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.2832 | 0.3965 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0076 | 0.0863 | 0.0863 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0166 | 0.0166 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.1072 | 0.1501 |
Trypanosoma brucei | glucosidase, putative | 0.011 | 0.1367 | 0.7497 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0486 | 0.7025 | 1 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0185 | 0.0185 |
Schistosoma mansoni | alpha-glucosidase | 0.0425 | 0.611 | 0.611 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0149 | 0.0149 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3635 | 0.3635 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0761 | 0.0761 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0448 | 0.0635 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0333 | 0.0814 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.032 | 0.453 | 0.6448 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0185 | 0.0262 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.0497 | 0.0696 |
Echinococcus granulosus | intermediate filament protein | 0.0058 | 0.0586 | 0.0586 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0133 | 0.0325 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0657 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0283 | 0.0283 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0041 | 0.0333 | 0.1825 |
Echinococcus multilocularis | GPCR, family 2 | 0.0099 | 0.12 | 0.12 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0553 | 0.0784 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0076 | 0.0863 | 0.1228 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 0.7058 |
Schistosoma mansoni | lamin | 0.0058 | 0.0586 | 0.0586 |
Onchocerca volvulus | 0.0236 | 0.3263 | 0.8043 | |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0185 | 0.0021 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0185 | 0.0259 |
Toxoplasma gondii | thioredoxin reductase | 0.014 | 0.1823 | 0.2583 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0166 | 0.0232 |
Schistosoma mansoni | hypothetical protein | 0.0213 | 0.2919 | 0.2919 |
Brugia malayi | intermediate filament protein | 0.0058 | 0.0586 | 0.082 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.225 | 0.225 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0076 | 0.0863 | 0.1222 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0333 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0863 | 0.1208 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0348 | 0.085 |
Brugia malayi | Probable ClpP-like protease | 0.0488 | 0.7058 | 0.988 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0494 | 0.7144 | 0.7144 |
Loa Loa (eye worm) | intermediate filament protein | 0.0058 | 0.0586 | 0.082 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.0137 | 0.0137 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0076 | 0.0863 | 0.0863 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.1367 | 0.7497 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0368 | 0.0368 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0931 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3635 | 0.3635 |
Loa Loa (eye worm) | thioredoxin reductase | 0.014 | 0.1823 | 0.2552 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.0481 | 0.0481 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0076 | 0.0863 | 0.4732 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0041 | 0.0333 | 0.0814 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0283 | 0.0397 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0076 | 0.0863 | 0.1222 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0863 | 0.1228 |
Echinococcus multilocularis | lamin dm0 | 0.0058 | 0.0586 | 0.0586 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.1072 | 0.1072 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1072 | 0.1072 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0319 | 0.4518 | 0.6432 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3635 | 0.3635 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0049 | 0.0448 | 0.0635 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0319 | 0.4518 | 0.6432 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0931 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0049 | 0.0448 | 0.2458 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.0481 | 0.264 |
Trichomonas vaginalis | esterase, putative | 0.0076 | 0.0863 | 0.2109 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3635 | 0.3635 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3635 | 0.3635 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.225 | 0.225 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.44 | 0.6159 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0657 | 0.3605 |
Trypanosoma brucei | trypanothione reductase | 0.014 | 0.1823 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0425 | 0.611 | 0.611 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0168 | 0.2248 | 0.3184 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0657 | 0.0931 |
Echinococcus granulosus | neuropeptide s receptor | 0.0475 | 0.6863 | 0.6863 |
Echinococcus multilocularis | geminin | 0.0168 | 0.225 | 0.225 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0166 | 0.0166 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0494 | 0.7144 | 0.7144 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.7058 | 0.988 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0488 | 0.7058 | 0.7058 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.0481 | 0.0481 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0049 | 0.0448 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0166 | 0.0232 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0488 | 0.7058 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0488 | 0.7058 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0261 | 0.3635 | 0.3635 |
Leishmania major | alpha glucosidase II subunit, putative | 0.011 | 0.1367 | 0.7497 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0761 | 0.0761 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0049 | 0.0448 | 0.1096 |
Mycobacterium tuberculosis | Probable reductase | 0.0319 | 0.4518 | 0.6432 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0041 | 0.0333 | 0.1825 |
Loa Loa (eye worm) | acetyltransferase | 0.0295 | 0.416 | 0.5823 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.011 | 0.1367 | 0.3341 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0041 | 0.0336 | 0.0336 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.0183 | 0.0257 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0494 | 0.7144 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0143 | 0.1875 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0168 | 0.2248 | 0.3184 |
Plasmodium falciparum | glutathione reductase | 0.014 | 0.1823 | 0.2583 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.0481 | 0.5254 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0049 | 0.0448 | 0.0635 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.014 | 0.1823 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0143 | 0.1875 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0294 | 0.0412 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.12 | 0.12 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0553 | 0.0553 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0303 | 0.0425 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.2832 | 0.3965 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0553 | 0.0553 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.1072 | 0.1501 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0481 | 0.264 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0041 | 0.0333 | 0.1825 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0488 | 0.7058 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0058 | 0.0586 | 0.0586 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0102 | 0.1246 | 0.1246 |
Onchocerca volvulus | 0.0058 | 0.0586 | 0.1065 | |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0761 | 0.1066 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0311 | 0.44 | 0.6159 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0481 | 0.1177 |
Toxoplasma gondii | hypothetical protein | 0.0168 | 0.2248 | 0.3184 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0368 | 0.0368 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0058 | 0.0586 | 0.082 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.011 | 0.1367 | 0.1936 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0333 | 0.0814 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0087 | 0.1025 | 0.1452 |
Plasmodium vivax | glutathione reductase, putative | 0.014 | 0.1823 | 0.2583 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0166 | 0.0166 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.011 | 0.1367 | 0.7289 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.0481 | 0.0481 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0481 | 0.1177 |
Trichomonas vaginalis | glutaminase, putative | 0.0291 | 0.409 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0087 | 0.1025 | 0.2506 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0488 | 0.7058 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.011 | 0.1367 | 0.3341 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0863 | 0.1208 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0049 | 0.0448 | 0.0635 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0099 | 0.12 | 0.168 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.032 | 0.453 | 0.453 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.0481 | 0.0481 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0863 | 0.0863 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.0481 | 0.264 |
Treponema pallidum | NADH oxidase | 0.0049 | 0.0448 | 0.0635 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.011 | 0.1367 | 0.3341 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0137 | 0.0192 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1072 | 0.1072 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0863 | 0.2109 |
Brugia malayi | jmjC domain containing protein | 0.0102 | 0.1246 | 0.1744 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0049 | 0.0448 | 0.4892 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0355 | 0.5054 | 0.7194 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0481 | 0.1177 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0049 | 0.0448 | 0.2458 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0049 | 0.0448 | 0.0635 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.1367 | 0.7497 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0099 | 0.12 | 0.12 |
Echinococcus multilocularis | musashi | 0.0058 | 0.0586 | 0.0586 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.011 | 0.1367 | 0.3341 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0303 | 0.0329 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0348 | 0.0445 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0448 | 0.0635 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.032 | 0.453 | 0.6448 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0303 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0518 | 0.0726 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0319 | 0.4518 | 0.6432 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0166 | 0.0235 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0143 | 0.1875 | 0.1875 |
Trichomonas vaginalis | set domain proteins, putative | 0.0236 | 0.3263 | 0.7977 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0049 | 0.0448 | 0.2458 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0283 | 0.0283 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.0137 | 0.0137 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.008 | 0.0916 | 0.1298 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0213 | 0.2919 | 0.4086 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0049 | 0.0448 | 0.2458 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.011 | 0.1367 | 0.3341 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0319 | 0.4518 | 0.6432 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0863 | 0.4732 |
Onchocerca volvulus | 0.0076 | 0.0863 | 0.1787 | |
Schistosoma mansoni | microtubule-associated protein tau | 0.0684 | 1 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0076 | 0.0863 | 0.1228 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0049 | 0.0448 | 0.0448 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.008 | 0.0916 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.014 | 0.1823 | 0.2583 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0185 | 0.0259 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0036 | 0.0255 | 0.0356 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.0481 | 0.264 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0303 | 0.0425 |
Loa Loa (eye worm) | RNA binding protein | 0.0261 | 0.3635 | 0.5088 |
Echinococcus granulosus | geminin | 0.0168 | 0.225 | 0.225 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.