Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.2597 | 0.3446 |
Echinococcus granulosus | tar DNA binding protein | 0.0048 | 0.4963 | 0.6586 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0809 | 0.1074 |
Echinococcus multilocularis | GPCR, family 2 | 0.0013 | 0.0809 | 0.1074 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.007 | 0.7535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0809 | 0.0809 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0013 | 0.0809 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.2597 | 0.2597 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0041 | 0.4137 | 0.4137 |
Brugia malayi | TAR-binding protein | 0.0048 | 0.4963 | 0.4963 |
Brugia malayi | RNA binding protein | 0.0048 | 0.4963 | 0.4963 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0091 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.007 | 0.7535 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.007 | 0.7535 | 0.7535 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0013 | 0.0809 | 0.0809 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0013 | 0.0809 | 0.0809 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0048 | 0.4963 | 0.4963 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0091 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0048 | 0.4963 | 0.4963 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.007 | 0.7535 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.007 | 0.7535 | 0.7535 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.007 | 0.7535 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0048 | 0.4963 | 0.4963 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0809 | 0.1074 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 0.4137 | 0.4137 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.007 | 0.7535 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0048 | 0.4963 | 0.6586 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4137 | 0.4137 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.007 | 0.7535 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 0.4137 | 0.4137 |
Loa Loa (eye worm) | TAR-binding protein | 0.0048 | 0.4963 | 0.4963 |
Echinococcus granulosus | GPCR family 2 | 0.0013 | 0.0809 | 0.1074 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.007 | 0.7535 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.2597 | 0.2597 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.